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<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULD9</accession>
    <name>A0A832ULD9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="109" mass="12234" checksum="0776F85DD62D115F" modified="2021-09-29" version="1">MEKLTRAPALERFVSEIRPEDIRVRVVGTVSDKSENSFELGDETGKILVKSASGFSFENGNKVRVFGRPVVAEKGVELEFELAQDMNLLNEKLYKKTITLNQNKDTDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULK5</accession>
    <name>A0A832ULK5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">H1011_01145</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="62"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="240"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="404"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="423"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="439"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="469" mass="52406" checksum="7DD3E5171571A008" modified="2021-09-29" version="1">MKENTKKVEKGNHQKPTPDATKTAINLSSVEAFKNLGITEDLLISIAEQGFVEPTEIQTKSIPSVLSGMDLMAKASTGSGKTLAFGSGIIQNSERKKGLQALVLTPTRELAIQAAKALQEFSKHKSLSVSAIYGGVSIRAQIQALRRVEIAIGTPGRLLDHMERGTIQLDNLKTLVLDEADRMLDMGFIDDVQKIIRACPKDRQTLLFSATLSSGVKKLARKYMRDPQEVFAESYVDPAKLEQCYYDVDDRLKFSLLLHLLKNEESELVMVFCNTRRFVDFVSKELNKNGVNATAIHGGFRQAKRTKTMDRFHSQNVQVLVCTDVAARGLDIPMVSHVYNFDIPKESNQYIHRIGRTARAGKEGKVINILGSRDYENFRKVKQESIGDIPRAEVPQFEQIIAQISRGRSQKPRYGGGNRRGPQRGGSQRSGPQRGGSHRRTGSHSHSSKYPRSRSSRRPTHRTSNYSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULL3</accession>
    <name>A0A832ULL3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TraB/GumN family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14726">
        <property type="entry name" value="TraB_PrgY-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002816">
        <property type="entry name" value="TraB/PrgY/GumN_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005230">
        <property type="entry name" value="TraB_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046345">
        <property type="entry name" value="TraB_PrgY-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21530">
        <property type="entry name" value="PTHR21530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01963">
        <property type="entry name" value="TraB_PrgY_gumN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00261">
        <property type="entry name" value="traB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="384" mass="42176" checksum="A344E57176461FEF" modified="2021-09-29" version="1">MAVEIVEIGGKRITIVGTAHVSKKSITEVKEVIAKEKPDSVAIELCRGRYEQLISGDGWQDMKINEILKSGKSHMLLLHLILMNFQRRIGDELGVKPGEEMLEAAKSAEKIGSNVVFADRPVEITMQRMLSMMGTREKIRVLFHLLAGMFETQVDEELIEKMKEKDVITEAIETLSGIAPSAKKALIDERDSYMAARILEAKGDNIVAVVGAGHVEGIKNLLERGVLVKVSSGPKTQEKRISRLRIVMYAIPVLFLGMIGYGLYTGGAELTLRLLLWWFLINGTLSAIGTAAAFGHPITIITAFLAAPFTSLNPMIAAGWVAGYVEALVRVPRVRDLDGLGKLNNWKGFWKNRVTRILLVVVLANLGSSIGTFVALPYLLTLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULU0</accession>
    <name>A0A832ULU0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">YhbY family RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_01930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001890">
        <property type="entry name" value="RNA-binding_CRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035920">
        <property type="entry name" value="YhbY-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01985">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01103">
        <property type="entry name" value="CRS1_YhbY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75471">
        <property type="entry name" value="SSF75471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51295">
        <property type="entry name" value="CRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="CRM" evidence="4">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00626"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="90" mass="10016" checksum="E4960146AB986BDD" modified="2021-09-29" version="1">MSSEFPPGLKKRANQLPPSIRVGKSGLTEKAINEIKARLEKKELIKVKFLNTAINGNKKELFKELAERTDSVLVLTVGFTASLYKKKSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULV9</accession>
    <name>A0A832ULV9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="193" mass="22236" checksum="D2BF13666D899C04" modified="2021-09-29" version="1">LTGEEKYLDAVTNSLENLHKYSDWGRTDAYADTVESALYLASYVEMPDSVFIWMDEMMGDMNRIGLEHDYKDGNYIRTSLMYALYHTKGAYLEEWRSGTRIGGHIENGTLYLHISVDEPRNVTIMLDTPRHANILGLERNYPRLNAFPEWYVVSDSSYTITVDEFSETISNIKNGFLVYVDDSVNIKIEPNYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UM85</accession>
    <name>A0A832UM85_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Signal peptide peptidase SppA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">sppA</name>
        <name evidence="4" type="ORF">H1011_03120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S49 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07023">
        <property type="entry name" value="S49_Sppa_N_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004635">
        <property type="entry name" value="Pept_S49_SppA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002142">
        <property type="entry name" value="Peptidase_S49"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01343">
        <property type="entry name" value="Peptidase_S49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00706">
        <property type="entry name" value="SppA_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S49" evidence="3">
        <location>
            <begin position="102"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="295" mass="31732" checksum="74CD9043E84492A4" modified="2021-09-29" version="1">MAKKVGRRTKTLIISLIIISVILILSGWSDGVSFENSVAVVKLEGIITSSGGFMDETMTVSEFSKLFGRAEDSSNVKAIVVEINSPGGSPVASAEIASIIMKSEKPVVAWIADVGASGAYWVATSADKIVSHPLSITCSIGAYIQISDFSRLLEDYNVSQTTIKSGEHKDIGSPFRQMTEDEEAIFQNIVDQINEEFVRVVRERREGADLSEVSDGRPCTGKEALELGLVDSVGSRESAISLAEELAGEEDLNIVEIESEGSFLESLIGSYTDRIARTIGLTIINSINSLPSFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UM95</accession>
    <name>A0A832UM95_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HIT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="PTHR46648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="7"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="94"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="130" mass="14564" checksum="F60CAD5E33978494" modified="2021-09-29" version="1">MASENCIFCKIAAGDIPAKRLWEDGSHIAFLDIRPASKGHALVIPKEHSESFLDMTKDSEKELFGAVQEVGKKLKESFGAEKIFVLLMGEEVPHTHVHLIPYYGKMPLSLNHEEGLDLDKILEEFGNTEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UMB7</accession>
    <name>A0A832UMB7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Minichromosome maintenance protein MCM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_03390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the MCM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032508">
        <property type="term" value="P:DNA duplex unwinding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031327">
        <property type="entry name" value="MCM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041562">
        <property type="entry name" value="MCM_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033762">
        <property type="entry name" value="MCM_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11630">
        <property type="entry name" value="PTHR11630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00493">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17855">
        <property type="entry name" value="MCM_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17207">
        <property type="entry name" value="MCM_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00350">
        <property type="entry name" value="MCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50051">
        <property type="entry name" value="MCM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MCM" evidence="3">
        <location>
            <begin position="281"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="681" mass="76058" checksum="8A597745A13CCA01" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UMC6</accession>
    <name>A0A832UMC6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="478" mass="54879" checksum="2E5BCEFF64E733F2" modified="2021-09-29" version="1">MKRLIIILIALILIAPSVYAHHSSTNLESITDSSRIVKERELVEEIDDDIMDVDSLETLDEMGIVKGHDDEGLFKPETETALKELNLILTDFGMSKKTNGIIKDLSSSIDAASEGISEFDKEMQMRNLENLRSLISESGESEEEKKNAMALVEQVQMFFDNPRITDMEANEPRGIEEVDPGQMIRQGISEVRQILNRINSENKEAIQFEAMSLLKEIKSFTDSAKLDDDERERFDSQIEKLKFLIRSVESSDVKQARLIKKKAATLSKDEIRKVRVRVTKVSEDADCEESDDREERIRCRLSVVKKHGTYLVSEERHDSDECRNLEGEQKESCNLKYRAYRKCTEIHEGRADVLVCVRKALGTEKNVKEDVSECRQMEGEDRTECNSEVKDRVYDTIKIRLQGLQDKAEEYLSRAYVSEELASRLINAIELKKEEFDSAETLGEKREVINQVKRIWSAFVETGKSEYRIQQGAEINEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UMD8</accession>
    <name>A0A832UMD8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="74" mass="7867" checksum="9935FBA7EC5C30D2" modified="2021-09-29" version="1">MSKYSLGSKERLAKLFLSATALSLLLFMFVYTGNSTSGLSISESLGPAGGLYAIVLASVTVLLGAVIWLVYYKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPC3</accession>
    <name>A0A832UPC3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Galactokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001174">
        <property type="entry name" value="Galkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014606">
        <property type="entry name" value="Heptose_7-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036406">
        <property type="entry name" value="Hept_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00960">
        <property type="entry name" value="LMBPPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_C" evidence="1">
        <location>
            <begin position="230"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="328" mass="36091" checksum="AAB2635FDF06431E" modified="2021-09-29" version="1">MIISKTPLRVTFGGGCTDFPSYYEDHGGFLVNAAIDKYTFIILHRKFDNKIRAKYSICEVVDDVEDLKNPIIKEALKSVGSPTGIEIVSLSDIPKETQLGQTGSYTVGLLEALNQWNDEHIPTEELATKSCNILIDILKKPVGKQDPYIAAYGGITCFDISKDGEVKASPLQISSETTEDLEKNILFFFTDFTQASAEILGDQLSKGGKLASDVVENLHKVKDVSYRIKDALEKGDTIEFGKLLSEHWKLKKERSPSSTTPQVDKLYSSALENGAIGGKLVGAGGGGFLMFYAEDAKKLREKMAEAGAREMKFSFDFEGSRVMLNTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPD6</accession>
    <name>A0A832UPD6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="299" mass="33672" checksum="E0A3299F8B149611" modified="2021-09-29" version="1">MKNRKAQLIFLQFFLIALLLSAEVTVTYMAKKNAAGIEAKSEVKNIILGSIQEFEGKTVFYDSFLRESIRRYAIDEIQADCDTEYTISEFYTDISTHQKIFLEREDYDAYTQGGSSKFDPWAESPVDCSDQTQSGFQLQSCVIPQCDCDLGQLYIGPGTDELEDTDCNGYENPTKTVSVGTPPVTQTIAMEIGDRCWDVYQPSMDSTDLNYAVFTTTGDEENNKELTYADAELQLRFGKQDLIKTLSLNYNGNMNFVKDFCTISVVSNYGYRVTEQLKGKFGIYGSSDEITNCRAPLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPJ8</accession>
    <name>A0A832UPJ8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_01000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051276">
        <property type="term" value="P:chromosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="3">
        <location>
            <begin position="348"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="495"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="829" mass="92815" checksum="C48E76AECC8FBF96" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPR9</accession>
    <name>A0A832UPR9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific)</fullName>
            <ecNumber evidence="2">2.5.1.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Undecaprenyl diphosphate synthase</fullName>
            <shortName evidence="2">UDS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Undecaprenyl pyrophosphate synthase</fullName>
            <shortName evidence="2">UPP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">uppS</name>
        <name evidence="3" type="ORF">H1011_01775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>geranylgeranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + tri-trans,hepta-cis-undecaprenyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27622"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:60388"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="2.5.1.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.89" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000010">
        <property type="protein sequence ID" value="HIJ99536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="177"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="222" mass="25468" checksum="7AE6650E83488692" modified="2021-09-29" version="1">MNYPLHMAIIPDGCRRWSSEKGSLPWDGHLKGIEVMETVSKWLLSETPVKHLTAYGLSASNLRRPSVQLKALEKLYVKYFTKLSKDEDIHENQVRVGIIGSRDLVPEKVLKATDIAVEATADYDSKFFRVALAYSGRQEIVDAAKKSEGNLSVESISRNLYSDYPDVDLIFRTSECRLSDFMLWGSSYSELYFLDKYWPDVTIDDIKTALEDYDSRQRRHGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPX6</accession>
    <name>A0A832UPX6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Peptide chain release factor subunit 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Translation termination factor aRF1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">prf1</name>
        <name evidence="11" type="ORF">H1011_02355</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of two subunits, one of which binds GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the eukaryotic release factor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00424">
        <property type="entry name" value="Rel_fact_arch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_1_Pelota"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024049">
        <property type="entry name" value="eRF1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020918">
        <property type="entry name" value="Peptide_chain-rel_aRF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004403">
        <property type="entry name" value="Peptide_chain-rel_eRF1/aRF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10113">
        <property type="entry name" value="PTHR10113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55481">
        <property type="entry name" value="SSF55481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03676">
        <property type="entry name" value="aRF1/eRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1_1" evidence="10">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="397" mass="44223" checksum="DE2C956CD87C9F13" modified="2021-09-29" version="1">MTQQEFELKKKLKYLGSLKGRHTEFITVYISAGYDMNKTIRLLSEEIGTASNIKSKATKKHVTNSLEKIIGELRLFKKTPDNGLAVFCGNIAEGVGQTDYLIETIIPPEKLSINLYRCSKTFVLEPLLDLLEHHDTYGIILVDRRDADIGTLKGRRIEILNSLDSMVPGKFRAGGQSAQRFERVIEGMAQDFYKKVSEAANKELGDIENLKGIVLGGPGPTKNDFLDAGHLRPELVKKILGIVDTGYTGKSGIDEMLHKSDDIIAESEIIQEKKLLEKYFEEISKKKGLATIGYLHVKDLLAQGAVELLLISEKLDQPVSIYVCEQCGKEYIDEKNCRRCEMALEPEAENIDIADELTEIANTMGTSVEIIGTSSQLGLQFYKLGVGIGAFLRYKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPY4</accession>
    <name>A0A832UPY4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="239" mass="27930" checksum="D15140F4C6E75406" modified="2021-09-29" version="1">MRIGARVFSISVDEDEYLTIINRLEKKYSLIVDPRKFDTPLKINARFKPRDSKTRYIELNSSGMAYVEHSGLKKDAEKILAAFKVLISSMMGEMQVKEEDFEIVTMELLSRKKPLLMPNDKEELQTFRRLETKNILSRAQPVKCPRCSQSFLLLYENLINPEHRVLCSDCTFWFSPKNKKEVYVVNEEYMKVMSGVWNKVQKIINASWREVTRHGLPMMGRGSTIDEKKPEKKTPSKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQ03</accession>
    <name>A0A832UQ03_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UL30 family ribosomal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039699">
        <property type="entry name" value="Ribosomal_L7/L30"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524">
        <property type="entry name" value="PTHR11524"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L30" evidence="2">
        <location>
            <begin position="19"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="129" mass="14011" checksum="3868E57A90CAEE9F" modified="2021-09-29" version="1">MTEEPKSKKAKEKKGKICVILLRGSVGVNPKIRETLKTLNLNSVNNCIILEDTSSTKGALKVLQGYTTWGEADASLEKDIKASGREKVPYGLHPPRGGLERKGKRNLFSGGGSLGYRGSAINSLVRRML</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQG8</accession>
    <name>A0A832UQG8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000017">
        <property type="protein sequence ID" value="HIJ99881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="640" mass="73405" checksum="60C7423C815106BE" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832USY5</accession>
    <name>A0A832USY5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Redox-regulated ATPase YchF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_00005</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013646">
        <property type="entry name" value="MMR_HSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08438">
        <property type="entry name" value="MMR_HSR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="2">
        <location>
            <begin position="3"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="3">
        <location>
            <begin position="307"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="385" mass="42071" checksum="56E9DF3D281AA6AD" modified="2021-09-29" version="1">MGKLVGVVGKPNAGKSTFFNANTLGNAETGSYPFTTIKPNRGVGYIRADCPCTELGNSCGKCKKGTRFIPVELLDVAGLVPDAHKGRGLGNQFLNDLAQADAFIHVVDASGSTDVEGQICEAGSHNPEEDVTFLENELDLWFLSLIEKGWGKITREAAHSKKEVHKELADKFSGIKVKEWEILAAARKAELDLEKAKDWPEEDLKKFATALREVSMPILICANKIDLETAKLLENSVPTSADSELALRKADESEIIDYKPGDSDFKILEASDEHMKVLEIIKRDVLEKYGSTGVQQCLEKVVSETLNLIPVYPVEDESKLTDKKGNVLPDVHLVPAGTTAKDFAYLIHTDIGDAFLCGIDARTKKKVGADYELKAGDVIKIVVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UT70</accession>
    <name>A0A832UT70_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Exosome complex exonuclease Rrp41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_00735</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016896">
        <property type="term" value="F:exoribonuclease activity, producing 5'-phosphomonoesters"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11366">
        <property type="entry name" value="RNase_PH_archRRP41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011807">
        <property type="entry name" value="Rrp41"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02065">
        <property type="entry name" value="ECX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_PH" evidence="5">
        <location>
            <begin position="24"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="6">
        <location>
            <begin position="156"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="240" mass="26328" checksum="1C3A628AAF502305" modified="2021-09-29" version="1">MMGTSKGEALIVDGKRLDGRKFDELRPIKIEAGVLEQADGSAYVEMGGSHVLAAVYGPVEMHPRHKMLPDRVVLQTQYEMAPFSVPDRKRPGPDRRSKEIAKVTKEALESVIYVEDYAQSAIRLHIEILQADAGTRVTGLTAASVALADAGIKMRDMVAACASGKIDDTIVLDLNGIEDNTGQADLPVAYAVGLDEITLLQMDGLMTEDEFEQGLKYAIDGCKTIYELQKDALKRRYKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTR5</accession>
    <name>A0A832UTR5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Divalent-cation tolerance protein CutA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004323">
        <property type="entry name" value="Ion_tolerance_CutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419">
        <property type="entry name" value="PTHR23419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03091">
        <property type="entry name" value="CutA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="97" mass="11313" checksum="EB8F489062E02995" modified="2021-09-29" version="1">MIYTTTRNKEDAKKIGKTLVEEGLAFCVNIIPNCSSIYFWKGKMEESDEAVLIIKTQENFEGVQKRIDELHNYEVPEILKINIDDLNKKYLDWSSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UU96</accession>
    <name>A0A832UU96_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF424 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007355">
        <property type="entry name" value="DUF424"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04242">
        <property type="entry name" value="DUF424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="97" mass="10511" checksum="1BDE43A1E75D9B7F" modified="2021-09-29" version="1">MIYARIISSGSDSILAACDKELLGKTFSEGDISITVDKDFYGDEEVDLESFKEMLNLSSISNLVGEKCVSISIELGLVTENNVLKIEGVPHAQILSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UUA7</accession>
    <name>A0A832UUA7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Magnesium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_03455</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045349">
        <property type="entry name" value="SLC41A1-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16228">
        <property type="entry name" value="PTHR16228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="126"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MgtE" evidence="7">
        <location>
            <begin position="53"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="MgtE" evidence="7">
        <location>
            <begin position="265"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="403" mass="42601" checksum="6533CA94A01F296F" modified="2021-09-29" version="1">MKFLLSFISENAKELKESSAALFLSIFASAVAGAFLSNSKEMLLIIPGLIILIPGATNMRGAIFGAVGARLGSAFHLGQIKSFSLKNDIVKTNVLSSVYLSVIFPVMLASLASLFSRLLGYKGATISTFITIAFIGSIVAGSILLVVTFFIAFTAYGRGWDPDNVTAPLIASIGDIITLPSLLFAAWLTLRFSRFSGYFSLAVIGLLMALVVSILLGGDSKTRTIVIQSAVVLSVTTLLNTLSGLLLQEKLVALIAIPSILVLLPAFLSQGGNIGSIFASRFSTKLHLGIIQEKGRGRIETIKEMLGAYTFALLIFPAVGVISIGISGFMGIPNILGAKLVLVSLFGGLIVTTIVVLASFYISIFFMRRSIDPDNVIVPIITSLADILGVVSLVIVLTLFGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UXR1</accession>
    <name>A0A832UXR1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CCA-adding enzyme</fullName>
            <ecNumber evidence="8">2.7.7.72</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">CCA tRNA nucleotidyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNA CCA-pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNA adenylyl-/cytidylyl- transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNA-NT</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">cca</name>
        <name evidence="11" type="ORF">H1011_00050</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a tRNA precursor + ATP + 2 CTP = a tRNA with a 3' CCA end + 3 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:14433"/>
            <dbReference type="Rhea" id="RHEA-COMP:10465"/>
            <dbReference type="Rhea" id="RHEA-COMP:10468"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:74896"/>
            <dbReference type="ChEBI" id="CHEBI:83071"/>
            <dbReference type="EC" id="2.7.7.72"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">A single active site specifically recognizes both ATP and CTP and is responsible for their addition.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Archaeal CCA-adding enzyme subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.72" evidence="8"/>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004810">
        <property type="term" value="F:tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016437">
        <property type="term" value="F:tRNA cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042245">
        <property type="term" value="P:RNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001680">
        <property type="term" value="P:tRNA 3'-terminal CCA addition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05400">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01264">
        <property type="entry name" value="CCA_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008229">
        <property type="entry name" value="CCA-adding_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042090">
        <property type="entry name" value="CCA_tRNA_nucleotrans_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006116">
        <property type="entry name" value="NT_2-5OAS_ClassI-CCAase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011068">
        <property type="entry name" value="NuclTrfase_I-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015329">
        <property type="entry name" value="tRNA_NucTransf2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39643">
        <property type="entry name" value="PTHR39643"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09249">
        <property type="entry name" value="tRNA_NucTransf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005335">
        <property type="entry name" value="CCA_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55003">
        <property type="entry name" value="SSF55003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03671">
        <property type="entry name" value="cca_archaeal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0692">RNA repair</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 8 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="9">
        <location>
            <begin position="27"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA_NucTransf2" evidence="10">
        <location>
            <begin position="149"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF09249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="449" mass="51031" checksum="9CC46D0A5A284E3F" modified="2021-09-29" version="1">MEKLLKDVLERVIPSKEEVDAINKFTKSVLRTANDLGIEATVQGSIAKGTWVSGTHDVDVFICFKEDVSRSKLEKDGISFGKKIIKKLGGKPELVYAEHPYTRSTINEFILDIVPCYKLKSASKIKSAVDRTPFHTEYILKNFSGTQANEVRLLKRFMQGIGVYGAKEKVRGFSGYLCELLILEYGTFLNLLSSSGKWKLGHSIDNEDFGTTQNFDDSLIVIDPTDKNRNVAAALDKDKYEIFINACRAFQKKHSIEFFFPNEVESFSKDRLKKDLSKGGHLLIMEFKPPKVVEDILYSQLRKSAHTIVSFMKRANFPVLGYSYTSGELSHILIELETGSLPKKQKVDGPPTDVDQKFQDEFAKKHKKRKTWISGGRWHVEIDRTHTSPESLLNEIIKSPIDYGIGKYVIESLSKECKILTSSEILDSDSEELAKFITSYLSKKKPWEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UY61</accession>
    <name>A0A832UY61_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">V-type ATP synthase subunit D</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">V-ATPase subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpD</name>
        <name evidence="8" type="ORF">H1011_01170</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the V-ATPase D subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00271">
        <property type="entry name" value="ATP_synth_D_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002699">
        <property type="entry name" value="V_ATPase_D"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11671">
        <property type="entry name" value="PTHR11671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01813">
        <property type="entry name" value="ATP-synt_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00309">
        <property type="entry name" value="V_ATPase_subD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="144"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="204" mass="23505" checksum="AEDCB9D80E34EA31" modified="2021-09-29" version="1">MAEDIKPTRSELIKLKRKIKLAKNGYELLKKKKDGLIQEFFSILDEVRKNRDVLGEIHKKSITSLELSRAMDGTLAVESTAFSVTKNPEIKVHTKNIMGVSVPEIEIIQGEVLDERNYGIIGSSSYVDTVVDDYQELLEKIVLSAEMETAMKRLLLEIEKTRRRVSALEYIVIPRMEGQAKFIRARLEELERENLFKLKLIKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYI2</accession>
    <name>A0A832UYI2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_02200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="17"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="271"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="366" mass="39624" checksum="215C5A90447898E8" modified="2021-09-29" version="1">MLWEVIRAQLSRHKLRTALTILSIFIGIFLLTSTVSFSEGLRVTLEENMGLFSGVVVVMEEGASMTDPFSSELDDSLIEEIEALGDVEMARGFTMELSDAGIIAGMTSDAFAVYGFDVGFKDGEMFDDNSDKEVVLGSTYAKRNDKTVGDEVSIYGKKYEVVGILESIGSAGDDSSIFMPIEETQKISGKEDTVMMISVKSANIDDAENVANQIIGEFDVMALSDKEMMRQVQDLMGNLNIAIYAIGIISSLVAGIVIMNVMFMSVSERTSEIGAMKAIGATNKQILSEVITESVTMSLIGGISAVLLSFGLAKSLNLYLDTRLMEVTGRLIIIAVLYSGFLGALGSFLPARQAMNIDPIEALRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYJ1</accession>
    <name>A0A832UYJ1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative pterin-4-alpha-carbinolamine dehydratase</fullName>
            <shortName evidence="4">PHS</shortName>
            <ecNumber evidence="4">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pterin carbinolamine dehydratase</fullName>
            <shortName evidence="4">PCD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_02275</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00434">
        <property type="entry name" value="Pterin_4_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTHR12599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="SSF55248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="110" mass="12561" checksum="78DE1C5C2869A64E" modified="2021-09-29" version="1">MVSELTKMKCKPCEGGVPPLKGEDLQKNLEQVEGWEIIEEHHLVKEWKFPDFKTALEFVNNIGEIAEEQGHHPNIDFTWGKVKISFWTHSIGGLSVNDFIMAAKIDDLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYK9</accession>
    <name>A0A832UYK9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YIP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="277" mass="29984" checksum="B641C49F42BF4514" modified="2021-09-29" version="1">MTKEGLGEYIKQQIALGHSEENIRQHLISFGHDIRKIDTAIEGITKPKPRQVQVGPRQAVKKTLKERELSIADYLTMWVRVFVSPTAIFTKERTAARLPNSMAHLAIAGVFGGLIGGLITVISTIFTGASTEALDSGIGISSIFGKAGALKSFSHILVYPLVAILLWISFSALLHFFSLAIGGKKSFRTHSHLIAISMAPIVLLLAMVSAIPNTCVIFIAYLIAGMMWFYPLTIATKVSHGFDTVKAILAWAIPMIVIVAYTAPYIVSVFATIAAAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYP5</accession>
    <name>A0A832UYP5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1624 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="HGSNAT_cat" evidence="2">
        <location>
            <begin position="5"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="237" mass="27319" checksum="3D16B6F57690C9D7" modified="2021-09-29" version="1">MEKDRLWEIDALRGIAISAMIAFHFLFDLNYFGSLGWKIGQGGWWIFARSIALTFILLVGISLTLSYNRNRRSLAHYTRRGLKIFSWGLLITAVTWIFLKEGTIYFGILHFIGLSIILAYPFLARRKSAFVVGLLALFAGIVMMEKRVQTYSLLWLGIAPSNFYTFDYFPLFPWFGYVLFGIFIGNSLYKNGKRHYRLPDFSKMKVIKFLSFLGRNSLLLYLIHQPISIALVLAIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYS3</accession>
    <name>A0A832UYS3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytidine/deoxycytidylate deaminase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_00020</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016473">
        <property type="entry name" value="dCMP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="PTHR11086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006019">
        <property type="entry name" value="dCMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="5">
        <location>
            <begin position="21"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="165" mass="18340" checksum="AC5CF609E9A24B17" modified="2021-09-29" version="1">MEKETPHYSLPNEEAEKNRTSWDTYFVDITNLVKERSTCNRAKVGAILVKNRRIISTGYNGAAKGTKHCSEVGCNVIKAGENPENLRDHCSRTIHAEQNAIIQAALFGVGIDGATLYCTHTPCYTCAKMIANAGVKEVIYMKTYDDKDSIAAFEEAGIKLREYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYU5</accession>
    <name>A0A832UYU5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MoaD/ThiS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="66" mass="7185" checksum="912B6E62D571BFC9" modified="2021-09-29" version="1">MKIKIVRKEGKKIIELPDGARASDIFGKLGESSETYIIKRASDIIIGEEPLSDGDELELIKIISGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYW9</accession>
    <name>A0A832UYW9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">H1011_03415</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="PTHR42780"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="12"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="10">
        <location>
            <begin position="660"/>
            <end position="811"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="946" mass="109905" checksum="4A78A10913FA9401" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYY0</accession>
    <name>A0A832UYY0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="550" mass="62075" checksum="A5DB2C42EA4A8276" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYZ0</accession>
    <name>A0A832UYZ0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="196" mass="22613" checksum="07B444812ACBA0ED" modified="2021-09-29" version="1">MAKNTLSKKADMHFKEVLVAIKKKKDWLSGDFKGLTQPANNPKKELDILLDLIEELGDDEEELRAALLAVGVETRRLLDSIESEEELAHFGKKGEFLLGKEKELSRAIDHQVNLLFNLHNLIRDIISDILKKSDLHIKSGRVISNIDNQLSYLETIIFEEELPNLSISFNELEFEHWPKMHKRLHELKLKVKPMPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZ36</accession>
    <name>A0A832UZ36_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate kinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="7"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="312" mass="34348" checksum="83F236D111D69E5A" modified="2021-09-29" version="1">MASKFDLVTVGNISIDTILVDKKCYRVPGGSAAAVATAAVANSSKCGIVSKLGRDYPSKWLDELKKSGVDASGLGKKKTSTRFELSYNRNKRLIKFNEVFSSDAVLSFSDMPDSYRNARQIHLSAAKPQHQENFLESLSNRKNQSVSLTLWSTYSDSYTDNFINLLKKTDVLFCNNHEISSISNEENIYDAVKVVQKKGPKIIVLTKGELGSAICTSRKIHLFPALKTSRTDTTGCGDSFAGGFISEYLRTGNVARAGWVGSALASFTMQKSGAWFPLDIQREKILKTVKRAKEAHASNGKRKTKGTLLDYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZ52</accession>
    <name>A0A832UZ52_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lysine biosynthesis protein LysW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005906">
        <property type="entry name" value="LysW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40393">
        <property type="entry name" value="PTHR40393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="54" mass="5836" checksum="D78EF036FCFB4351" modified="2021-09-29" version="1">MTKCIECEAEISLPAGLEKGEVIDCPECGVELEVVNAEKGELRVAEVEGEDWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZ76</accession>
    <name>A0A832UZ76_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="139" mass="15578" checksum="621E583711AD8F18" modified="2021-09-29" version="1">MPAPNSRELETQLRSIKKSTLDALNPETGVMDNKTIFEQGVALKVWLGEFETLYLNEAASKPSKTGKLKTEGEKILEFGWHCYEILVEADLQSGSASSPARRWEPIEYGTVLGKLKEQIVSSLTKLENDYTVFIKTVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZE1</accession>
    <name>A0A832UZE1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="7">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA threonylcarbamoyladenosine biosynthesis protein Kae1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">kae1</name>
        <name evidence="9" type="ORF">H1011_00010</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="7">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="7"/>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01446">
        <property type="entry name" value="Kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022449">
        <property type="entry name" value="Kae1_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034680">
        <property type="entry name" value="Kae1_archaea_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF14">
        <property type="entry name" value="PTHR11735:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03722">
        <property type="entry name" value="arch_KAE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="8">
        <location>
            <begin position="28"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="129"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="327" mass="35301" checksum="40CC1944AB56EC17" modified="2021-09-29" version="1">MRVLGIESTAHTLGIGVVEGDGKVLSSARQTYIPEEGGILPSESADFLASKFEEVLQESLDVSGCSFNDIDGIAFSQGPGLGPCLRVGAAAARYLALKHKKPLIGVNHCIAHIEIAKVTTGAKDPVILYVSGGNSQVIAYAEGRYRVFGETLDIAVGNCLDAFSRVLGLQHPGGPKIEKLAAKGKNYIELPYVVKGMDLSFSGLYSDLKRKKLSGQYSDEDLCYSFQETAFAMLTEATERAMAHLDKEEVLATGGVAANSRLQNMLEIMAKERGAKYYGCPREHCGDNGAMIAWAGLLMLKSNDTLDIKNSKINPKFRTDDVDVTWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZG1</accession>
    <name>A0A832UZG1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000010">
        <property type="protein sequence ID" value="HIJ99532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="161" mass="17811" checksum="122918A9E6FE78F2" modified="2021-09-29" version="1">MIKNRKAWIKLVGLVLASVLIFASIMYLQSLQLTESSQPGDWGNVILNTYAKDSLNSLWRSDLNNDSSKDLAKFVIDQVWTSADGPFNLEGELTKMLPDHIGFTFYLYDNGTISRKGGSLVGLQPSTKEIVSVDRTISGANVNSTCTVVPCSIYLALWFIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V059</accession>
    <name>A0A832V059_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
            <ecNumber evidence="6">4.2.1.136</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ADP-dependent NAD(P)HX dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nnrD</name>
        <name evidence="7" type="ORF">H1011_03635</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01049">
        <property type="entry name" value="YJEF_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="264" mass="28481" checksum="992B4407D057FB5F" modified="2021-09-29" version="1">MKIVLERHSDSHKGSNGRVLVIGGSEIYTGAPALTGEAAFRSGVDIVYIAAPYRAADACANRLPDFITLPLHGNIFEHRHVEELDRWIKKSTSIVIGPGLGRDERTLVAVKELILEIDKPLVIDADGLRAIFDDLSVLKGKEVVLTPHRLEFEMLSGKNAIKTNVSSFAKENKCVVLLKAPNDIVSDGEQTYLNKSGNAGMTVGGTGDVLAGIVAGFLAQGLSSYDAAQYAAYVNGRAGDECYRQFGYSFIASDLLKMIPQVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V063</accession>
    <name>A0A832V063_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="308" mass="35852" checksum="0AF6C98756E48C88" modified="2021-09-29" version="1">MVSLEELEKFEEILKNGKITPETVGALRELRKVKTQRKGQIHKDKRRDSAEVRKRAEEILENFIDSYIINVLNEEREDIVNDVIGEKGTEVRTLFHTRVVNELEFTGRGIFSTQNCVDSIKRLQKRAEKEPEISEILKYYEAALYMNERYTVKIWTYMRFIEKDPDVDYASLGENQFWWGSSGEINDSENLEILEQAVKDKKIPKKIKERLAGLIEVRKLGREKLEAIETKLATSVAAKLAELIEKEPDITEKDAFDKLFRVEGIDEDNIRELIRLAVKNLTKQGERDSDLCRSLVKLYGKVSTRRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0C0</accession>
    <name>A0A832V0C0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="57" mass="6543" checksum="27A0C6EF699DCA8B" modified="2021-09-29" version="1">MNINKANKILRYSSLAAIVLVLLTGVSLNWNFFITISIVFAILLVRISMLLYFIRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0G6</accession>
    <name>A0A832V0G6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000010">
        <property type="protein sequence ID" value="HIJ99537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="105"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="353" mass="39135" checksum="552694B6375AED4E" modified="2021-09-29" version="1">MDSQVTIVGGGPAGLHLSRKLKEKGIDSTVYESSPDLGRPVQCSGVFSNNFAELLEMPKKIILNQVKGAKLYSPSKKIVEISKGEKQADIVDRGEYDRHLAKGLDVREGEHVNSLDFDSEYIVGADGAHSTVARLAGFPPLEKHVIGVQVEIDNDSYDKDFVELHLGQSVAPGFFAWIIPTDKNLRVGLGTTEKPKEYLDRFIEERFGKIEQRECLAGFIPMRVRKPMWKGNIALVGDAAGQVKATTGGGIYMGMKSAEILADAIEAKDLNIYEKRFTKEIYPDLKKAVAINKVLSSMTDEELNKFWDTLGKESMVKLMQEYGDMDKPTLLLKGFLKNPGLITQVPFIRGLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0H5</accession>
    <name>A0A832V0H5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor 1-alpha</fullName>
            <shortName evidence="6">EF-1-alpha</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Elongation factor Tu</fullName>
            <shortName evidence="6">EF-Tu</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">tuf</name>
        <name evidence="8" type="ORF">H1011_01860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_A">
        <property type="entry name" value="EF_Tu_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004539">
        <property type="entry name" value="Transl_elong_EF1A_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SSF50465"/>
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    </dbReference>
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        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EF-1_alpha"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
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    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="4"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="13"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="90"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="145"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="426" mass="46688" checksum="605FCE59A18CFF35" modified="2021-09-29" version="1">MADKSHMNLVFVGHVDHGKSTSVGRILFDTGNIPEQEMKKIQEEAKTLGKETFGLAFVMDRLKEERERGLTIDVAHKKFETQKYNFTIIDAPGHRDFVKNMITGASQADAAVLVVSAKEGIQPQTKEHAWLLKTLGVNQLIVTINKMDEVDWKEERFNEVKKTVEDLLKPVGVKIDEVTFIPTAAYVTGENMTADAGEHMGWYKGLSLVKRFDELVPPEKATDKPLRMPIQDAYSITGVGVVPVGRVESGILKPGMKLIFQPSGATGEVKTVEMHHEQLTQAEPGDNVGINVRGLDKGSVKRGDVAGEVSNPPQVAETFEAQVVILQHPSAITAGYTPVIHCHTAQVACTIEEIIKKMDPKTGQEVTENKEMLKSGDSAVIRFRPTKPFVLETAADFPPLGRFAIRDMGATVGAGIVTKVTPKKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0J7</accession>
    <name>A0A832V0J7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="70" mass="7519" checksum="91DCF0649712D8B7" modified="2021-09-29" version="1">MQTETPDGLVTKAEEIVRESPRGVSIQDVAQKLRVSRYQANGILGILIGSGKVGVSQIGPVKVHYWKGGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0X3</accession>
    <name>A0A832V0X3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="409"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="2">
        <location>
            <begin position="58"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="533" mass="62197" checksum="11A6DD420D7627BE" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0X9</accession>
    <name>A0A832V0X9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000017">
        <property type="protein sequence ID" value="HIJ99882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="320" mass="36620" checksum="A12EBC09BE2DD4DD" modified="2021-09-29" version="1">MKDLIKSLDFAKSSDMDSSIMQSGQGISKYDLNPVSPELFSAYEPYEAPKDFKLAAFDGGSLMIYETPTIGFAYYKLAFRQFQVNLEEKTCTTVEINKDIQHGLFLLSHNPSEGFESYKDFENGSLLKTKETEFILGKLDLIDESDLLLIDGSIERETLPILEKHPNTMAVSKRTFHTIGGYSAQSFMAKKAKEYEKDSVPWFAYPIVKKYPERSPSQISFGTFRKNSVVFRLDFPNDFSENNVLDCMRKVGICALDSKYGAYPYPLGAVHSDAVMRRGTKDKLRRFIKKELREGNANAYERLKEDLHHAEWYDKMRGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V219</accession>
    <name>A0A832V219_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="612" mass="68638" checksum="14FE51B71608E384" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V249</accession>
    <name>A0A832V249_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="249" mass="27621" checksum="4D009CC983FBA5F6" modified="2021-09-29" version="1">MNITARGSVYFILLAFFLLSAGMLASESELTAKLTGKVVGAPDCIATLKMTPGHAEIVLAPGSSAETTLTISDVQCGASYIRLDIEDLPSEYFGFAPTYLRTLTPGDTGRFIIYLDIPLDAEYKAYTATYKLYTSEGRYAGPELTLSIEDVKKPQFSARTESITEGSPAEKESMGNKQFWWMIMLGAVVFVTAIYASEYFEKKVHENEVKRKGPSQGKTTLRSLVKRAKKREEGKIERVSKALKKVKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V268</accession>
    <name>A0A832V268_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Cysteine desulfurase</fullName>
            <ecNumber evidence="3 5">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_02480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="3 5"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="25"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="407" mass="45442" checksum="8FEBAA32E3067DE7" modified="2021-09-29" version="1">MSLNTEKIRKDFPILKREINGNALVYFDNASTSQKPQSVIDSISSFYTNSNANVHRGTSTLSEEASELYEGAHRKVADFIGADSIAEIAFTNNTTESLNLIAYSWGLNNLRKNDEVVITRMEHHSNLIPWQQICNKTGAQLKFIELNEDYTLNLEKAEEIMSSRTKLVSAVHVSNSLGTINDVKTLGKIAHDNNALMVVDGAQSAPHMEIDVKDIDCDFFAFSGHKMLGPTGIGALYGQEERMKELEPFNFGGGMISEVEYDSAKWNVSPWKFEAGTPNIAQGIGFGEAVDYLSNVGMNKIYKHEKELTKYALEELENFEDLRMYIPPLEKLAGIISFTMEGIHPHDISALVDEEGVAIRGGHHCTQPLMKLLGIDATARASFYLYNTKEEIDIFVEALKKARDLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2H5</accession>
    <name>A0A832V2H5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1206 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="151"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="237" mass="26966" checksum="33183C45C21D9D06" modified="2021-09-29" version="1">MSKARTRSKAPKNPKKRASRKKVVEEAGIEIIEAEDVKKTAQAQEVKPIKVVLKENKADEELETPKDIQEKKVEKVLETLGEAVSQEVSTKIEKDIRKINKNPITFTLESPTVRRQIGNLKEVAGSGLHSTRRNVIIFYERASIIGDRTRGFLYLLLGMSIFFTGFFATQENLLTFKDIISTLMTEWIGRLLVVVIGLSLGAFGMDRMFPGHLEKWKKHTVPKVRKKYTQRKLNEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3J5</accession>
    <name>A0A832V3J5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="1">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">carA</name>
        <name evidence="3" type="ORF">H1011_00375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="1 3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="2">
        <location>
            <begin position="3"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="335"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="361" mass="39760" checksum="31B3A4D39326F777" modified="2021-09-29" version="1">MGEKALLVLEDGVVFKGEFFGASSEVFGEVVFSTGMTGYQEALTDPSYRGQILTMTYPLAGNYGINSEDFESNEIQVRGLLVSGACEFPSNHRAEKTLGTFLKDYKIPGLQGIDTRALTRKLRKHGTMRGKICREGIDTEKVAEELRKTPYPDNEDLLPEVSRNNEEIYEADGNLKVTLIDCGAKENIIRCLVKRGVTVRVVPARTGAEDILKEADGVMISNGPGDPSKASYVIDTVKSLFGEIPLFGICLGHQIIGLAAGAKAYKLKFGHRGLNHGVKELETGRVHITTQNHGYSIDEKSLEKTGFEVTHVNLNDGSVEGMRHKDLPIFSVQYHPEGCPGPRDNEYLFDKFVEAMNAKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3S3</accession>
    <name>A0A832V3S3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphate uptake regulator PhoU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="9"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="82"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="314" mass="36035" checksum="B0600FC5E7556E3F" modified="2021-09-29" version="1">MAEVRKIQKTGGSTYIVSLPKKWIVRQKLSKGASLLLSENGDGSLSVRIGKQNPKTLSETEIFAGPNVERHLLEKYLLGYDIVKVSDGKESLEKRKKELKNTLRFLLGYEIMEEASNRIVIHNLLNPSEISISKSVRRMYTIVSVMHKDIIKSLKTGSKTLLKDVAQRDEEVNRLYFLVVRQIRKVLETPSLMDHEKISAPDCIDYRLVARFIEQMGDSLQSIAESLLTLKKLPRQKQVLNYMENSYEMHQMASRGFFKKKELFALEAISLGKNIKYDKISESKDLAPIIHNLIKLNDYTQDLADIVRTEYISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3S9</accession>
    <name>A0A832V3S9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2391 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024464">
        <property type="entry name" value="DUF2391"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09622">
        <property type="entry name" value="DUF2391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="11"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="190" mass="21588" checksum="B09720D85BD3B46A" modified="2021-09-29" version="1">MPKAAKKTKKKTETQKGLEKIEEDIETLEQLVRTERKEEKLEFGEFEKELAGLRKLSNPIIEKFTFKDFSRGFIGGIIGMSSIAWHEVVIEGARAMHPAFVFIITLFTLFAGASVLYFSQYRKIKEQKIIFKLLPKRFVVFYFLSLLIVLTTYTFFGIVGPGHSFTESVKLILVVALPTMIGASAADIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3Y2</accession>
    <name>A0A832V3Y2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5652 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043712">
        <property type="entry name" value="DUF5652"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18893">
        <property type="entry name" value="DUF5652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5652" evidence="2">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="76" mass="9235" checksum="729C08F9ED499696" modified="2021-09-29" version="1">MLMSNPTYPLFWLVLIWAVIWKGFALWHSVRNLQKKWFIALLVINTLGVLEIAYLFLFRKDRFKKDILGRKIKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3Y6</accession>
    <name>A0A832V3Y6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Signal recognition particle 54 kDa protein</fullName>
            <shortName evidence="8">SRP54</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ffh</name>
        <name evidence="8" type="synonym">srp54</name>
        <name evidence="10" type="ORF">H1011_02030</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="8">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="9">
        <location>
            <begin position="265"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="106"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="186"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="244"/>
            <end position="247"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="443" mass="49046" checksum="01559256ABFED1E1" modified="2021-09-29" version="1">MVLEGLGKSLRDGIRRIAKAGYVDRNTLDEVIKDIQRAMLSADVNVKLVFGMTENIKSRAWDEKPPEGLSKREHILKIVYEEITAALGGKVEAKELGKVSRIMLVGLFGSGKTTTCGKLARHLKKQGLKVALISTDTWRPAAYEQLKQIGEEIDVPVFGNPKEKSALKVLKASLKEAKSFDVIIVDSAGRDTVDKELSKELKKLDKEFNAEEKLLVIPADLGQKAEPVAKGFNELIGIDGVILTKLDSTAKGGGALSACSSLNVPIKFVGIGERSEDFEAFKPDKFVGKLLGMGDLESLVKKTQEIFGEVEEDQVQAMLKGDFNLKDLYKQIEGMKKMGPLKKVMEMMPMGADIPTDQMDMSQERMNSFMVIMDSMTNSEMEDSDLLDKSRVERIATGAGTSVENVRTLLKQYKMTKKMMKRFGKNQGSLKKMMKNFKGFPGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3Z9</accession>
    <name>A0A832V3Z9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">H1011_02180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000179">
        <property type="term" value="F:rRNA (adenine-N6,N6-)-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="31"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="259" mass="29563" checksum="B4BED449E387111D" modified="2021-09-29" version="1">MLLQDLKKILKENNFFLSKSLDQHFLYSDSILEREVEYAEINSEDKLLEIGPGIGTLTEKILEKTRNLAVIEIDPKFASILNKNVEEVIIGDALKVEWPECNKIISNVPYSISSPLIFKILEQPIELAVLCLQKEFARRMVAEPGTKNYSRLSVNCAVRADVEFLETVPKGKFFPVPRVDSAFVRLRPKNIVLPRKFADITRAIFQHKNKKLRNSLMDSYHEIGTKEEVASFVKSLGEIAQTKVLNLSPEDIINISKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V460</accession>
    <name>A0A832V460_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prolyl oligopeptidase family serine peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="77"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="268" mass="30110" checksum="3D9AAB280592ACC8" modified="2021-09-29" version="1">MTGEHTQVKFKNSRELELVGILSESPGSKSAVVLCHGFGGYKEMKLLHSTAEAIRSRGISVLRFDFSDCMLESEGDCKNLTVTNQIDDIGAAFDYLEAQGFEKIGIAGHSLGGFDSIIFSVKDSRPKAVVTFGAIASARNDVFFRDHIEEWKTSGHKKFSLEKWGEVEIPYTFYEDFKKYDASELIKEMKAPIRIIHGKQDKIVTMLNAEQLFDNAAAMKDVRIIMSAGHMFSEEFEQTHAAKMAAEWFEEFLLGKSNKFKQPEPIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V474</accession>
    <name>A0A832V474_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="323" mass="38230" checksum="8E6C1109146D4770" modified="2021-09-29" version="1">MKPTTYRKSREEYKIEKFFETLEGYESDTHLLPIGERVNKLDELHRVGSLALEVLKGGKTWKVYLRETRGGVKKYYKHFPRIRRFENREKVTQKLEKFLWEIEEELKLAKETLEDMERIFSKYGARLKKQKIGQITVPPSLRPVKLSVKDHLTQRKFVKKTILCLSSKDTDAWYEKVIKKFEKSMEKTYGRFSLSSSKIPLIDIEHRHVKEQKAFAFTQYRIEKKLMTVDYIQLVIYYLKGVRPSNTGYFYAGSRSPRKANIHKAELLLLYHLLKIAEEDKVEEIKISLHARREGHGEGIFPVYEEVKTASTEIEGSWVIFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V480</accession>
    <name>A0A832V480_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">tRNA-intron lyase</fullName>
            <ecNumber evidence="3">4.6.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">endA</name>
        <name evidence="3" type="ORF">H1011_03045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.16" evidence="3"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000213">
        <property type="term" value="F:tRNA-intron endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006388">
        <property type="term" value="P:tRNA splicing, via endonucleolytic cleavage and ligation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036167">
        <property type="entry name" value="tRNA_intron_Endo_cat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006677">
        <property type="entry name" value="tRNA_intron_Endonuc_cat-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006678">
        <property type="entry name" value="tRNA_intron_Endonuc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036740">
        <property type="entry name" value="tRNA_intron_Endonuc_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006676">
        <property type="entry name" value="tRNA_splic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016442">
        <property type="entry name" value="tRNA_splic_arch_short"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21227">
        <property type="entry name" value="PTHR21227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01974">
        <property type="entry name" value="tRNA_int_endo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02778">
        <property type="entry name" value="tRNA_int_endo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005285">
        <property type="entry name" value="tRNA_splic_archaea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53032">
        <property type="entry name" value="SSF53032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55267">
        <property type="entry name" value="SSF55267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00324">
        <property type="entry name" value="endA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_int_endo_N" evidence="2">
        <location>
            <begin position="8"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA_int_endo" evidence="1">
        <location>
            <begin position="86"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="177" mass="19698" checksum="8B1D9CBFE67AC498" modified="2021-09-29" version="1">MPSNKVASGMLVGGNVLVSDQKEANSLNQKGYFGEIGKGGKLTIPLVEALYLVENTKLRVSKGKKVMDFDTLLAYAEERDAGAFVQYLAFSDIRDRGYIVKSGFKFGAHFRIYERGNVPGEDHAKYLIHALPENFSMTLTEFSRLVRLGHSVKKELWIAVVDNDSGVTYYTLGRVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V494</accession>
    <name>A0A832V494_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="11"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="193" mass="21997" checksum="47DD01209C096A50" modified="2021-09-29" version="1">MTLIDTVQASYPIGSEAIDFNLPGIDNQDHNLASFKDKEVLIIVFTCNHCPFAQGYFPRLIKIQEDYKDKGVQLVGINPNDSENYPDDSFESMKPFAEEYEINFPYLRDESQETAKAYHAACTPDIFVFDKERKLRYRGKIDETTGAINEPGYTPEEGNEHYLRDALDAILEGTEIETPEIPVIGCSIKWKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V7W6</accession>
    <name>A0A832V7W6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NTP transferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_00380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023915">
        <property type="entry name" value="Bifunctiontional_GlmU_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03992">
        <property type="entry name" value="Arch_glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="7">
        <location>
            <begin position="2"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00007947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="407" mass="44089" checksum="D315CD01A72982E5" modified="2021-09-29" version="1">MKGVILAAGGGTRLAPLTNTRAKPAIPVANKPLIEHIIASLKGAGIEDIVIIVNTSGELEKLLEDGSQLGVKLKYVVQEEQLGTAHAISLVKEMVTEPFILVNGDNLVPRSVVNELIEKFNGTATITLLKAEDLSSLSTCELDGNKVLKIIEKPKPGEELSPYASIGTYAFSPEIFDYIDKVEKSPRGEYELPSAMDLMLRDGKEMTWVETEQFQHLSHPWDMLSETVVFLDVMEESREGTIEEGAILKGKVSIGKGTVIKSGAYIEGPVLIGENCTIGPNCFIRAYTTIGNNCRVGNAVEIKNSVIFDGTNIPHLSYIGDSVIGENVNFGAGTVLANFRLDKKNIKMEIKGELVDTERKKLGAIVGDNTKFGSNVVVNPGRKIGANCNIWPGTVVTKDLDDGEDYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V825</accession>
    <name>A0A832V825_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000005">
        <property type="protein sequence ID" value="HIJ99355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="573"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="637"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="677"/>
            <end position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="702" mass="78080" checksum="D76EE3F83D024AF5" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8H5</accession>
    <name>A0A832V8H5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="147" mass="17171" checksum="3742D4B941D654DF" modified="2021-09-29" version="1">MAKDLENDLEKARVRTEAVIQQCKVALEDYHTAEEHASEMLARIWLLYDDIEVQQVWPDHEDRILELQEEYVRLGGSANNRLIAKVKNFESIMKEKVTSIKDSIGLIEETRQETEEDAEFFNNITAEMQRVADALEEIRNTFQRETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8L7</accession>
    <name>A0A832V8L7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl12p</name>
        <name evidence="4" type="synonym">rpl12</name>
        <name evidence="6" type="ORF">H1011_02260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006414">
        <property type="term" value="P:translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05832">
        <property type="entry name" value="Ribosomal_L12p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_L12/P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022295">
        <property type="entry name" value="Ribosomal_L12_arc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03685">
        <property type="entry name" value="ribo_P1_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="69"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="103" mass="10294" checksum="748302D46D38696E" modified="2021-09-29" version="1">MQYVYGALLLHSAGKPVDEASLKKVVEASGTASDEAQIKALVASLDGVDIEQAIKEAAVPVAAPAAAAAPAAEKAGEAKEEKSAEDEAKEEEAASAGLSALFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8M9</accession>
    <name>A0A832V8M9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Valine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Valyl-tRNA synthetase</fullName>
            <shortName evidence="6">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">valS</name>
        <name evidence="10" type="ORF">H1011_02350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02005">
        <property type="entry name" value="Val_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022874">
        <property type="entry name" value="Valine-tRNA_ligase_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="8">
        <location>
            <begin position="16"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="9">
        <location>
            <begin position="604"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="6">
        <location>
            <begin position="44"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="6">
        <location>
            <begin position="526"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="529"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="803" mass="92295" checksum="41588459933C5637" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V900</accession>
    <name>A0A832V900_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Orotidine 5'-phosphate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="234" mass="25819" checksum="3B5D913C3606B77C" modified="2021-09-29" version="1">MDFGKTPKIVVSADIAPNEAVQLAEKLLPARDKIAALKLGSLHAMDVGLRETIKMMKEVSDFPLIYDHQKGCSDIPDIVERQVLLASDCGIDAVIGVPHGAGPRSLERFCTSCKSAGIEAIVLLEMTHEGAHDYHKEDTPRKIFDHIMELGVRNIVAPGNKYERLREYRKWIDESGSEMKIMSPGIGAQGGQAEKAVEIGTDYPIVGRAIYLSEDPLKAVEEIYESAVRGYEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V910</accession>
    <name>A0A832V910_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">30S ribosomal protein S19e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_03400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01474">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001266">
        <property type="entry name" value="Ribosomal_S19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027548">
        <property type="entry name" value="Ribosomal_S19e_archaeal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018277">
        <property type="entry name" value="Ribosomal_S19e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710">
        <property type="entry name" value="PTHR11710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01090">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01413">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00628">
        <property type="entry name" value="RIBOSOMAL_S19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="132"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="138"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="193" mass="21741" checksum="9EF24894AF0D1A41" modified="2021-09-29" version="1" fragment="single">MVSTLDTNTNALIDAAKEELKSLESLKKPEWAHYAKSGAHKERPPHTDDFWQIRAAALMRKLYKKGPIGVSRLRKEYGGRKNRGAKPEKHYDGSGNIIRKILQQLETAGYVKKVKGGRELTSAGMKFLDGISHKVETSSQSSEEKAPKESKKEAETERIEAPEAKEIKKEAETERIEAPEAKEIKKEAETERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X4X3</accession>
    <name>A0A832X4X3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isopentenyl phosphate kinase</fullName>
            <ecNumber evidence="3">2.7.4.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_00485</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + isopentenyl phosphate = ADP + isopentenyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:33963"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:65078"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the isopentenyl phosphate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.26" evidence="3"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04241">
        <property type="entry name" value="AAK_FomA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024192">
        <property type="entry name" value="Fosfomycin_R_FomA-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF1">
        <property type="entry name" value="PTHR43654:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016496">
        <property type="entry name" value="Kin_FomA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="12"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR016496-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR016496-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="268" mass="29136" checksum="B5FB0EF37BCC18FC" modified="2021-09-29" version="1">MSEDVKKTVFVKLGGSAITHKGKESQANLPVIDLSSSQISELYNDFSLILAHGGGGFAHPVAERHNVSKGIEKCKALGLANTRMAIQGLNSIVLTSLLSKEVPALTISPSTCSEMENGRFTDFNLSPIHHAQKLGAVPLLHGDVVYDSVKGCSVASTEMIFSYLSTRIKPERIVIGANVDGVFWDNPDNGKRELVEEINSRNLEDVLSAVEEPKTSDVTGGMRHKIEELYNISKHKIEIFIVNLSKKNYLRGAILGKPEVGTRIKAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X504</accession>
    <name>A0A832X504_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutathione S-transferase N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004045">
        <property type="entry name" value="Glutathione_S-Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13417">
        <property type="entry name" value="GST_N_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50404">
        <property type="entry name" value="GST_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GST N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="80" mass="9385" checksum="41D727FEEAA16F29" modified="2021-09-29" version="1">MKLYIYETCPYCIKVRNTLKELGYKEGKDIILLDANKEENANELIELGGKLQVPFLIDGETMMYESSDIMEYLREKKNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X590</accession>
    <name>A0A832X590_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="48"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="106" mass="12477" checksum="03ED6608C7132753" modified="2021-09-29" version="1">MKKNIFEGVPENLELSEEFIDKIINTENLIIKRIISKGHKSPKGEWYDQDKNEWVLLIKGSARLAYEDGEKISLKEGDHINIPAHTKHRLDWTDPEQDTVWLLVYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5G0</accession>
    <name>A0A832X5G0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glycine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.14</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glyS</name>
        <name evidence="8" type="ORF">H1011_03070</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="PTHR10745"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="7">
        <location>
            <begin position="7"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="488" mass="56589" checksum="F612DAF925B32F0D" modified="2021-09-29" version="1">MPERKYDRILRIAKSRGFMWPSSEIYGGIGGFFDYGPLGSLLKQNIENKWREIFIIREGMSEIETPTLMPESVFLASGHIDHFDDPLVECKKCQENYRADHIVEEKLEISTDAMGVKELQKLISENKIKCKCGGTFSEVWAFNLMFKSEAGAGKIKRDVYLRPETAQGMFVAFDRLYQVGRKKLPMGVCQIGRSFRNEISPRQGMIRLREFTQAEAEIFYNPRKKEHPKFSRIKNHILPLYTEKYQEEERKEVLEMTVEDAVKDGVIASQLQAYYLVLAEKFFEEIGIPRSKMRCRQQLSDERAHYSSETWDIEILSEDFGWVEVAAIADRTDYDVSRHAATSRKKLEVHDEGEKFIPHVMEASFGIDRPFYCLLEQSFVEEEDRTYFKFTSEMAPIKAGIFPLVKKDGLPEKAEEIFSDLIKNKIIVKYDSGGSIGKRYARFDEIGTPYCITVDHDTLEDGKVTIRKRDTTEQEYCKTEDIVEKLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFM2</accession>
    <name>A0A832XFM2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_00580</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007238">
        <property type="entry name" value="DNA_primase_lsu_euk/arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04104">
        <property type="entry name" value="DNA_primase_lrg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0639">Primosome</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="388"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="390"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="417" mass="48174" checksum="3A7BB824B9DDE532" modified="2021-09-29" version="1">MYKEEIESYYSRTDVQRAILEVSENREVIPVLSTGSFGSRPNAVYYEKDVGQMVKSGAIEFHCSVERWKDPLKLKTGMRKEDQDALRIGWDLIIDIDCKKTLEEAKTACIILLDRIEELNIHNYGVKFSGNRGFHIVVPFEAFPAEIMGMGKIAKNYPDLPRKMIQYLADTTFETMKEEFGEDPRNVLEIDQGVISPRHLFRAPYALNRKTWLASIPLEKKEIRNFDPQSAQPSKVKVKRKFLKETKENEAIELLRASAYWTSTRKKDSERKEIAFEVPKDAIPVKFFPGCIENIMSGLDDGRKRSVFILVSFLHRIGWERDDVWAFLVDWNKKNKPPLADNLLKSSFTSQYTGEGPKMSPNCSNPGYYGGFGEEQCEHRNPVSYTLGRVRALKRKRPKKRRAKTKKETKQEKEVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFP8</accession>
    <name>A0A832XFP8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class III-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="394" mass="43194" checksum="4780CAABC3571E74" modified="2021-09-29" version="1">MEKERYSYMDKEDKFIESVYSKRKIELVRGKGAIVFDSEGKEYIDCFNGQGVALVGHGVEEINSAVKEQMDKISVVALSFYNDVRAEFGEKLASISPKGMTQAFLANSGTEAIECAIKLSKKYTGKPGIVAMSGGFHGRSLGSLSATWKPMYRKQYEPLLPDFSHAKFNDIESLKQTITEKTGAVMLELVQGEKGVVLADKEYVKELREFCTEKELLLIIDDVQAFARTGNFFSSQTYNIVPDITAIAKGMAGGIPMGACIASPEIMDAFKPGDHGTTMGGNPIACAAGTATIDYIQKNNLIEHGASMGERMLKGLKELESFNVVREARGIGAMLALEYKFKMAGVLPKIQESGVIPLTSGKRALRFLPPLCISEEQADKVIEVTKKVTEEFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFX6</accession>
    <name>A0A832XFX6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TrkH family potassium uptake protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_02150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="405"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="461"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="495" mass="54106" checksum="09098BC773838F4C" modified="2021-09-29" version="1">MKHQFVRTVLYYLGLALTITGFIMLLPAVAAYFFQELVSAFLIPATISIISGIFMMTRYEAGEVTMGRAMTLSALAFIVIALVGAIPYMMQAQTVYGEVGVNAYVSAYFESMSGFTTTGLSTLPDITAVPESLLFWRSLTQWIGGVGIVVLFLLFFVSKTIGSSVPGMSAYYLFRGGANEERLEPSTSKSVKGIAKIYIFYTIAGLAIYRIAGMPLMDAINHILTSVSTGGFSTQAASTGTYGSAWLDASIGVFMIVGATSFLLHYKLLGLRWKDLGKFAKSYEMKVWFIFMAIFSGALSLYLWSSGVENPAWKGIFQIVSASTTTGFVNMDLAGMGDLGLLLLIFVMFIGGSAGSTAGGLKIIRFLILLEAIPWTVRKFLLPKKAVLPLKFGTRIFGKDEISQVSVYLFIYLFITFIGTIILTIIGYPFIESLFEITSAAATVGMSTGITQYTMPIIGKIVLILEMLLGRLEILPVLVLFMAALNRKRWGSFYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFZ2</accession>
    <name>A0A832XFZ2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Agmatinase</fullName>
            <ecNumber evidence="4">3.5.3.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">speB</name>
        <name evidence="4" type="ORF">H1011_02390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.11" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="293" mass="32493" checksum="9C6FED29AC557652" modified="2021-09-29" version="1">MDFYLNKFCRLSGARNSVKDSKVIFLGVPYDWSTIDRPGSRYGPLHIRKSFEQFLGYDSTSEKDLYESLLPCDLGDIEVVPGDYTETLKRTEETLGKILSENSKAFLVGLGGEHSITYSFLKSLRKVNEDFVVVSFDAHPDLKEDYMGNTETNVTYLRRVCDFVEPSSIILVGIRDADRDEMDYVKKNNITILHGKAIKDDLGASLSAFKKAIKGKKLYLTIDVDVLDTAIAPGTSSPSPGGLSMDEMKAFLDICVPQAIGMDIVEVSPPFDIGETTSFTAAKLIYYALSLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG12</accession>
    <name>A0A832XG12_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">30S ribosomal protein S14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="48" mass="5492" checksum="82134EFA026E7D30" modified="2021-09-29" version="1">MASRKIGKTSSNCTLCKSYNRKVRKYGINLCGRCFREEAPSIGFKKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG23</accession>
    <name>A0A832XG23_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Diphosphomevalonate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_02775</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041431">
        <property type="entry name" value="Mvd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18376">
        <property type="entry name" value="MDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="5">
        <location>
            <begin position="88"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="MDD_C" evidence="6">
        <location>
            <begin position="182"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="314" mass="34535" checksum="7530DF787460C38D" modified="2021-09-29" version="1">MARASAHPMQGLVKYHGLKDPVKRIPYHGSISVCTDPLESITSVEFHEGEHDQLEIDGNLISGRAFERVVAVLDKVRELSETTERAIVHSKNSFPQGVGLGSSSSGFAALALAAFEDSGADYDMKLVSETARLGSGSACRAVTGGISEWITDDSGSYSIQIGAPEDFKDWSIVVPLVESITVTEKAHEEVETSPLFKARLDYIEKTLCQMKDAVENKEVEKIWKLAEQDTRNLHAVTMTGNEGLFAWNAATAEIIHRTTELREEFPVYYSIDTGATPYLNTYREHEKQLISEFRETHGVTDILVCSVGGPAKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHE0</accession>
    <name>A0A832XHE0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonuclease P protein component 2</fullName>
            <shortName evidence="2">RNase P component 2</shortName>
            <ecNumber evidence="2">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Pop5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rnp2</name>
        <name evidence="3" type="ORF">H1011_00715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Consists of a catalytic RNA component and at least 4-5 protein subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00755">
        <property type="entry name" value="RNase_P_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002759">
        <property type="entry name" value="Pop5/Rpp14/Rnp2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016434">
        <property type="entry name" value="Rnp2_archaea"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01900">
        <property type="entry name" value="RNase_P_Rpp14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004952">
        <property type="entry name" value="RNase_P_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160350">
        <property type="entry name" value="SSF160350"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="117" mass="13129" checksum="7D02AFE967FBB85F" modified="2021-09-29" version="1">MVKFKVKPTLKENWRYISFELLSENKISEKQIVSEILNSLLSLLGELGASNANLWLIEYDSKTSSGIVRCSNKALTEVIASFATITNIGGSRTTFRVLGVSGTIKKTKDKYLNRKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHJ4</accession>
    <name>A0A832XHJ4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridoxal phosphate-dependent aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="33"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="391" mass="43360" checksum="B440B5AE224EFFD3" modified="2021-09-29" version="1">MSPILSSVESSITESPIRRIAQLLEKAGDDSSIISFGGGAPSLAPPKEVVDAMISSLRKDPFKAVSYTSTKGLPSLREKIAEDLTKSGDSVDSNQIALSTGATGGLFMALEDIVNPGDEVIVSDPTYVGYEGPALIERAKLRRIPVKKENDFQLTPDAVNETITKKTKIIIILSPDNPTGRIQKKKNVKGIADIAKDNNLWIVSDDTYKDIIYEGSHTYIHKYAPENTITACTFSKSSSIPGLRLGYVYGPKEAIDGITKFSQYVMLCTNKLSQAAAEAFYPVKETYLNKTVIPTYKKRRDVMGNMIKKHLSVCDYVKPHGAFYYFVDLCDSKLDDEEFCNRLLEEQKVVAIPGKYFGNEGKGHIRLTFVSENEKRIEEGILKIKDFMEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHL7</accession>
    <name>A0A832XHL7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="264" mass="30976" checksum="C03A09FF7C750978" modified="2021-09-29" version="1">MELHDEEFLETEQALIERIRNFGQDDFADALENAIEFGGLDRRKRPGETEEAYEDFLRDCPWACFGSETSILFNRSSPGVVRYQRQATRITHVFTYFLGSKYLPKRGDSTRVWFKDKLHSQLVTGVSKRRGGSKGMGNILYSINYEKRFFRIMMLYASADHRPTWQRVLEYLYEHPRSSAPDISEGVGLGKNSFTSMIIPASGPIPNMLRGENPILIKEAQQYKYNLRDEFREVYEDFYPWISSEEGIEIYKDWLELYHHPIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHU8</accession>
    <name>A0A832XHU8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA (Adenine-N1)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_03675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016429">
        <property type="term" value="F:tRNA (adenine-N1-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="PTHR12133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08704">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017269">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017269-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="247" mass="27397" checksum="092C55F76571E83B" modified="2021-09-29" version="1">MKIKKNDLVLLIGDRDYLVQAGAGKFGTRRGEIDLNALSKKKYGDTVKTHLGQSYTAVEPRTGDILKKIKRAPQIIGQKDAGYIAGRVCLGKDDIVLEAGTGSAAMTIFMAGIAKKIISYELRKDFYKIAKGNIERFGIKNVTIRNKSAEKGFTERNADIAMLDMGSPELVIPHIPKSLKPGGYLVVYSPVIEQVQRVHDAIKKSNSFTQADTEEVIMRRWDIGGNKTRPKTQMLGHTAFLTFARRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIG7</accession>
    <name>A0A832XIG7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="148" mass="16502" checksum="F7E41A191A19E72B" modified="2021-09-29" version="1">MEYIISQMTEVVRFNLFGSHYMMEMWSLAMVLGVVTYLQTAILTGSVPMSSMRGKINRIFGLVVISPIFEEIIFRMVLISALYGFFGAWLPAILVSAVMFGGAHTFYGRTRFVDSTITGLIFGWAFVSFGIFVPILAHATHNALASIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIJ5</accession>
    <name>A0A832XIJ5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="7">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">gltX</name>
        <name evidence="11" type="ORF">H1011_00795</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="7"/>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="9">
        <location>
            <begin position="99"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="10">
        <location>
            <begin position="414"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="106"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="533" mass="60692" checksum="6D9DD4BDB8E8DDA0" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIN7</accession>
    <name>A0A832XIN7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dihydroorotate dehydrogenase</fullName>
            <shortName evidence="8">DHOD</shortName>
            <shortName evidence="8">DHODase</shortName>
            <shortName evidence="8">DHOdehase</shortName>
            <ecNumber evidence="8">1.3.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pyrD</name>
        <name evidence="10" type="ORF">H1011_01570</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of dihydroorotate to orotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(S)-dihydroorotate + A = AH2 + orotate</text>
            <dbReference type="Rhea" id="RHEA:18073"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="8">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.-.-" evidence="8"/>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04740">
        <property type="entry name" value="DHOD_1B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00224">
        <property type="entry name" value="DHO_dh_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033888">
        <property type="entry name" value="DHOD_1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024920">
        <property type="entry name" value="Dihydroorotate_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01037">
        <property type="entry name" value="pyrD_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="9">
        <location>
            <begin position="5"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="70"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="190"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="46"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="241"/>
            <end position="242"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="263"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="300" mass="30875" checksum="F25162338553F572" modified="2021-09-29" version="1">MKPKLSVTLCGIKLDNPTVLASGIIGNTGELLKRAGDEGAGAVTTKSISLEPWDGHPSPNVVELEKGLLNAMGLPNPGAEDFVEEINIAKQGDAPVIASIVESTIQGYADVISILESSEPHMYELNASCPNVKGGQDISRSPELAGKLVEKACGVTNAPISFKISPDAGKLADVARAVDESGASAITAVNTLPAKAIDSKANLPVLYNKIGGLSGDLLRPIALRCVSEISDAVEIPIIGTGGVSTGQHAAEMISSGARAVGIGTAVWHHGVGVFKKVSNELSSIMEKKGFESVGDIEHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIQ9</accession>
    <name>A0A832XIQ9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">50S ribosome-binding GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003034">
        <property type="entry name" value="SAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02037">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00513">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68906">
        <property type="entry name" value="SSF68906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50800">
        <property type="entry name" value="SAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAP" evidence="1">
        <location>
            <begin position="112"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="276" mass="30847" checksum="092722E37643B152" modified="2021-09-29" version="1">MVRKLIKKLKGAFSRLFGRKRVIRLGIYGEPNTGKTTLANKISMDWMGKEVGIVSEMPHETRTIQKVEHIEVKAGKKTLVMNLLDMPGLSASVDFKEFTKFRESVSNTDTDFKDLKVSDLKRIAEEEDLSKTGKKAAIIQRLKAKISKKELQTYVKDLKIKVTAKKGKKISKASARKIAEEATKGIVEAIKWLDNVDSVIVMMDSTKDPMTQVNIMLLGNLEAKNIPIVIAANKIDAKNSKPNNIMSAFPQHPVVPISAKEGRNLENLYKTIAENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIR7</accession>
    <name>A0A832XIR7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Proline--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="6">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">proS</name>
        <name evidence="8" type="ORF">H1011_02300</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PTHR43382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="SSF64586"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="7">
        <location>
            <begin position="19"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="481" mass="55006" checksum="54E8012E59A1DDC1" modified="2021-09-29" version="1">MAEDQTAGITVKKDDDFGEWYNQLVLKAELADFTAIKGFMAIRPNGYSIWEKIQAYLDARFKETGHRNSYFPALIPEKFLTKEAQHIEGFAPEAFWVTQEGENDLEERLALRPTSETIMYDSYSKWIKSWRDLPLLLNVWCSVFRYETKTTKLFLRTREFLWQEGHTVHATREEADVEVRQQLDTYKDLCETLLAIPVIQGLKTDRERFAGALTTTSIEAIMPDGKALQMGTSHNLGQNFSKAFGIKFIDKDEKEKFAWQTSWGVSTRLIGALIMVHGDDKGLVLPPKLAETKAVVVPILFEDSKKKVLAASRKIAEKLSKDIAVHFDDRENYSAGWKFNEWELVGIPLRIELGPKDIEKKQAVVVRRDTGTKSFVKLSELNKFASAELEKMQKDMLSSARKFLKDNTHEVKSYNEFKKLMGSSRGFIIAQWCGSEDCEIKIQEETTATLRCIPLNKGKGSGKCVRCSKKSQHRAYFAKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIS2</accession>
    <name>A0A832XIS2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="19"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="251" mass="27363" checksum="CDC33C164690C279" modified="2021-09-29" version="1">MVLEALFTVEEAKQEPSNLFLLGVVISTVALWLSFYIFPQGASTWMLFIITLAIVPLMHKAFMGEEAKDMAHSKKLLRGHLPIIKMYLYLFLGIFVSLLFWYIFLPTHLLEIIFSVQMNVASTILTDGAILIMSLKVLTLFMLLTFIYGAGGILILAWDAALTSVIVGNLLKHVILGSYVPGMAAILLPAVFQIIAYSIAAVAAGILSVAFYKGHLKGKLAKYILIDFTVLSLVALVMLAVGALIAQGVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIT9</accession>
    <name>A0A832XIT9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl23</name>
        <name evidence="5" type="ORF">H1011_02685</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L29.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_A">
        <property type="entry name" value="Ribosomal_L23_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="86" mass="9602" checksum="94F84747665A9A3D" modified="2021-09-29" version="1">MEPYEILLYSLMTEKAVGMATSENKLTFAVSKNANKEEIANAVEKAYKVKVQKVVTQRTFKGLKKAIVRLDSQFSAEEIASRIGAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIZ1</accession>
    <name>A0A832XIZ1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="5">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aspartate transcarbamylase</fullName>
            <shortName evidence="5">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">pyrB</name>
        <name evidence="9" type="ORF">H1011_03680</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer of catalytic and regulatory chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="154"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="308" mass="34476" checksum="D34974DD1CFBD07E" modified="2021-09-29" version="1">MALKGKDIITLKDITKEDIEFILENAEIFEKKLKNGPLKLLEGKILATIFLEPSTRTRLSFESAMHKLGGRVLTVSKDEMTSLAKGETLSDTVRVIEGYCDVIVIRTPIEGAPKMVSDMVSVPVINGGDGAHSHPTQPFLDLYTLKKEFGKLEDLKVAIVGDLKYGRAVHSLAYALATMGTEMVFVSPKELRMPDSIIKVLKNEFGVEAEEKEKIEDVISEVDALYMTRIQRERFPHESEYEKMRSVYKLDSKIMKNAKEGMKILHPLPRMDEISPELDATKHACYFNQAHNGVPVRMAILAGVLGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL42</accession>
    <name>A0A832XL42_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_01035</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="346" mass="37910" checksum="7172D1C07A1D17B8" modified="2021-09-29" version="1">MVAASDLVLAAGNEYIQSAFYAMITVIAAIAMRYLTGTLLGTILGKFGSGRVLVAKVGRILSVIILLFGLSVSLSPLTVLTPYLSLINKVLYTVIIIITIRVVMLLTDKAIDRWVKKWAEKTEDTTDDQIIALLHKLTKAIGIIIVAVIILDIWGADIGPLLASLGIAGLAIAFAMQNTLGNLFGGVSIIIDRSVRPGDVIEIDTTIGTVEDVGLRSTRIRTFSNELIVIPNGQVADAKIINHILPSKRVRLTIPFGVEYGSDVDKVKKIVIKSVEKIENVLKDPKPMVRFTNMGDSALEFKVYIWINRFQNKFSVKDVANTAIYKDLNKAKIAIPFPQMDVHLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL62</accession>
    <name>A0A832XL62_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <shortName evidence="8">GAPDH</shortName>
            <ecNumber evidence="8 10">1.2.1.59</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">NAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gap</name>
        <name evidence="12" type="ORF">H1011_01425</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 8 10">
            <text>D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10300"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>D-glyceraldehyde 3-phosphate + NADP(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10296"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="1.2.1.59"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8 10">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 8 10">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.59" evidence="8 10"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00184"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00559">
        <property type="entry name" value="G3P_dehdrog_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006436">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_2_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01546">
        <property type="entry name" value="GAPDH-II_archae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 8 10" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="11">
        <location>
            <begin position="4"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="8">
        <location>
            <begin position="142"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="8">
        <location>
            <begin position="197"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="13"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="339" mass="37146" checksum="A32698EA48852F6B" modified="2021-09-29" version="1">MSKVKVAINGYGTIGKRVADAVSLQDDMEVLGVTKTKPTFEARLANDKGYPLYGISKESVKSFEEAGLKTEGVFDSLLEQADIIVDCTPGKVGAKNKEDLYIPKKLKAIYQGGEKASVGETSFVAQINYDSSIGKDHVRVVSCNTTGLSRAIGALSSKLSIGTVRAFLVRRSVDPRDSSKGPINAIIPDPLTVPSHHGPDIQTILPDLKVITSAVKVPTTLMHLHSLMVELKDDASESDVKNVLEQARRTKVLHSKEGFRSTAEVIEYARDLGRSRYDLYENMIWEDSIVVKDKEAYFFQGIAQESIVVPENIDAIRAVLELETDAEKSMDKTDKTLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLB5</accession>
    <name>A0A832XLB5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="132" mass="15263" checksum="5C7A3C684DEE389D" modified="2021-09-29" version="1">MKLLHHALAGLVLGWAFGYDLWLSMLFSIGPDIPQALILYPLLAYKHKRIILPLDGDWKNFSKSAWSHLYFAPHSLLFVAILNFSDFSAFFIGLYALHILVDIPTHTGEWSIRLMWPASWKIEGFFDAWKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLC4</accession>
    <name>A0A832XLC4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl4</name>
        <name evidence="6" type="ORF">H1011_02690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_A">
        <property type="entry name" value="Ribosomal_L4_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_L4_euk/arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019970">
        <property type="entry name" value="Ribosomall_L4-archaea"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="PTHR19431"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03672">
        <property type="entry name" value="rpl4p_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="73"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="278" mass="30226" checksum="EBA7C099A06C4871" modified="2021-09-29" version="1">MKATILKLDGTKGKSIDIPLVFSEEIRPDLIRRAFHAVTSRRYQPKGADPMAGFRTTAASWGTGGGMSRIPRTKAGPKRKGRSAKGRRYRSKGRWFPAAGRGAIIPGTVGGRQAHPPKSCKILIKKINTKELDKAMRSAIASTAVPELVKGRGHSIGDITLPLVVDDTFMSLEKTKVVKETLSAIGLSAELERTSKRSIRAGIGKLRGRKYRTKTGPLLVVPSSEEKQPILKAARNVPGVTAVSVNELDMDMLAPGSHAGRLTIWTESAIKDLQRRFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLD6</accession>
    <name>A0A832XLD6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="676" mass="78038" checksum="5D5543F20A1F7769" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULU8</accession>
    <name>A0A832ULU8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_02025</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="4">
        <location>
            <begin position="62"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="272" mass="29331" checksum="0C3AD2CAA2575A66" modified="2021-09-29" version="1">MAKKKSTSKKKSTVPKKSGLSKKARKSLTAKTPVQKVLLAGMAVLIIAALSLFLPSEGAEMGDTVTFSYSLQTADGGLSESGNLTLTLGGGRLILGVESALLGMSVGDTSSITVLPKDGYGEKNLSLVAKQFRYINLPLTTEADRSYIEEVLGDTPLGYGVEVELPGTHWKTTVGSISGDTVNITHYLVNGSLYYIFNYPYSLKVIDVTDDGYIVENLAKVGGPIQIQGRLGYIESVDDTFIYTDFNHPMAGKTLLFDLELLDIQRASEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPG2</accession>
    <name>A0A832UPG2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="154" mass="16955" checksum="D5AE7CD90A9609C1" modified="2021-09-29" version="1">MTVFGDLYSGFMSMLIFMFVAILVISLIAAFIIIKYGKRKEEGEQGTTSQAKFLTTKIGLILGVLLLVFMLIAGMSFKAAVLVFVIIIAISLIIDLVKSAGNKKPADTVSEKTEPAKKATQSGEKKGVLNPEDPRTAKLYEEYPFLKEKKDKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPH6</accession>
    <name>A0A832UPH6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-CASP ribonuclease aCPSF1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_00770</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019975">
        <property type="entry name" value="aCPSF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033769">
        <property type="entry name" value="KH_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17214">
        <property type="entry name" value="KH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03675">
        <property type="entry name" value="arCOG00543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="KH" evidence="2">
        <location>
            <begin position="91"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="3">
        <location>
            <begin position="194"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="4">
        <location>
            <begin position="422"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="638" mass="71316" checksum="A83760E366AE3497" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPI2</accession>
    <name>A0A832UPI2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YIP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_00845</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000005">
        <property type="protein sequence ID" value="HIJ99356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="6">
        <location>
            <begin position="9"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="212" mass="22725" checksum="B080FE0B7E8B57FA" modified="2021-09-29" version="1">MQVSAGTLKVLITPKAELTELKEHANWKHGAAVWLMLTFAGLAIYAAAEARLGTGFIPLDFGAGLELLPIPILTAMAKAFATLFIFIAIAHYVAKALGGKGNLETTFGLACYEQMLAPLMGLTAAGLQFKFVSMRAAFYEITTTGSIPDPFAYFGIYTVYLSVTVAIFTAWAFWIRSAAVSASHDLPYWPGLLSVFLAFAAIGLVNLGISFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPM5</accession>
    <name>A0A832UPM5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent DNA helicase Hel308</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">hel308</name>
        <name evidence="4" type="ORF">H1011_01310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the helicase family. Hel308 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00442">
        <property type="entry name" value="Helicase_Hel308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022965">
        <property type="entry name" value="Helicase_Hel308"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="38"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="235"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="699" mass="78602" checksum="CA4B8A3B293A92CA" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPN6</accession>
    <name>A0A832UPN6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flippase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_01470</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="212"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="320" mass="35844" checksum="95B22EA9E59010D2" modified="2021-09-29" version="1">MLSAKRFLPLIGLFLFAYIVNSVGVSVITEAFLKANPLYFIFALLLVFASSGIKAYKWKLGVDAQKPGFKFIDAWKAFIIGIFAAVITPGRIGEIIKAIYVADDRKIRTGKAFATVFIDRVVDTMLLFLLAIIGIYYMTAEFAIGFSTPKIAIVVFVVFAIVILLVLEEGVTRRMMRPIFRKLVPKRHQNILRTNFEEFYEGVRVIRRKRFLLTKIAGLTLIAWGIVFLQYYLLSLAAGINISFFYMTMIIPITMLAELIPISISGIGTRDLVLIGMLGLLGIGAGSAVAFSLIILLFNYFIASLGLLFWLADPVKIWRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPS6</accession>
    <name>A0A832UPS6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps10</name>
        <name evidence="6" type="ORF">H1011_01855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005729">
        <property type="entry name" value="Ribosomal_S10_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01046">
        <property type="entry name" value="uS10_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="6"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="103" mass="11846" checksum="F2E690D8DD66B365" modified="2021-09-29" version="1">MTTKARIRLTSRKIDLLNDICNKIKDIASDSKVKFAGPISLPTKKLKVTTRKSTDGEGTATFDRWEMRIHKRLLDVEPNERVMRQIMRIPIPDAVNIEIQVKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UT27</accession>
    <name>A0A832UT27_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNH" evidence="1">
        <location>
            <begin position="6"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="70" mass="8186" checksum="8056DC8EFE07674B" modified="2021-09-29" version="1">IEKLGYDHIIPLSKAPSGFVYTIDDIQPLCNPCNASKGNRLMKEYYKEYYEREEVKAKLKDTKIGRIVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTC0</accession>
    <name>A0A832UTC0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type-4 uracil-DNA glycosylase</fullName>
            <ecNumber evidence="3">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_01045</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="3"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005273">
        <property type="entry name" value="Ura-DNA_glyco_family4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00758">
        <property type="entry name" value="UDG_fam4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="9">
        <location>
            <begin position="31"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="205" mass="23311" checksum="5BAE5756454708A6" modified="2021-09-29" version="1">MNNQEKLDQIRKNILENKNLSLRESATNLVFGKGNSDAEILLIGEAPGEKEDLQGIPFVGRAGKELDKLLHMINLSLEEVYIANILKYRPPKNRDPKQSEIEEHTPYLIEQIKVIEPKVIVTLGNFATKFVLAGFDSNKMKEIDGITKLRGNPVKVSVDNAKFTVIPIYHPAAVLYRPAWREQLEEDFQKIGKLLQEKDKYSGKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTI6</accession>
    <name>A0A832UTI6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ParB N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023098">
        <property type="entry name" value="SerK/SbnI_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="1">
        <location>
            <begin position="13"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="245" mass="28079" checksum="AD0711880445EA13" modified="2021-09-29" version="1">MEILERSGDTIIALLNIEDLKDHEQINESYLAELTRKIKEDKEIKVPIVVDKHSNVVLDGHHRFYALKKLGCRRIPAFVVDYYNPDIKLNCWNHFVKTEEEREAVFDCLKEHNFLTSTVESEDVIKTLLSSGQAILGIAARNGGNNFFIVQSEDKKQTFEDALKCIKTGLSKELDYIPDAISMEEAMREQKASLVMIIPTVEKSDVVKKAVEGHPYPPKTTRHILSKHSEYPVPLRNLMSEERKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UU72</accession>
    <name>A0A832UU72_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">ftsZ</name>
        <name evidence="10" type="ORF">H1011_03175</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 6 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="8">
        <location>
            <begin position="25"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="9">
        <location>
            <begin position="218"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="330"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="338"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="33"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="121"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="363" mass="38093" checksum="2D352132A28C4252" modified="2021-09-29" version="1">MEFLVKNAMNREPEHSAAPAVGKAKIVVVGAGGAGNNSISRLMKMGGVHGAETVAVNTDMQHLESIKADTKILLGYKLTQGLGAGGYPDVGRKAAEDSRNEIREVMKGAHLVFLTCGLGGGTGTGAIPILADIAKKEGAIVIATVTTPFDLEKARLLKAEEGLSELRQVADTVIVIDNNKLVEQVPNLPLEEAFAVCDELIATMIKGISEIITVPSLVNLDFADIKSIMTGGGVAMIGIGESDTTNKVEEAVKSAMQHPLLDVDYTGGTGALIHIAGGPGMTLSEVTQAGDLISAELDPSAQVIWGARVDPELEGRIRVMTIVTGVKSPHILGRHSSQDVPEKNSTSSSEAPELMKELKIDYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UXS2</accession>
    <name>A0A832UXS2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lrp/AsnC ligand binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="14"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="75" mass="8300" checksum="7DEA2298FBD8C7F0" modified="2021-09-29" version="1">MVNAFILIMSKTGTERSVIRELSKLEEVVDVSVVYGDYDIIAKIQAETLEDLNSVILDKIRALDEVSNTSTLIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UXW5</accession>
    <name>A0A832UXW5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mevalonate kinase</fullName>
            <ecNumber evidence="2">2.7.1.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">mvk</name>
        <name evidence="12" type="ORF">H1011_00480</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="9">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GHMP kinase family. Mevalonate kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.36" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="PTHR43290"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="10">
        <location>
            <begin position="87"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="11">
        <location>
            <begin position="220"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="307" mass="32211" checksum="A81C322A32D711B2" modified="2021-09-29" version="1">MIRASAPGKLILFGDHAVVYGEPGIATAINKRVYSTACELEGRKIIIESKDTGETIECGIRDKSKNPIVAAVQEAQKFSKSRSGVGVEINSQIPIGAGLGSSAAVATATIASVATLFNGKEPSTMEIAEMAYKADKLAHESPSGIDTAITSLGGTIFFKKGNISQLDSDPLTFVVANSGVRRNTSDMVLRVKNSIMDPRVALSMFSIGSLAKEARTVFMNKRPVDLGPLMDRGQSLLKDLGVSSTAIEDLVKLAKDSGAIGSKITGAGGGGCIISLSDDPEDLIKAFKENGAFAYSVRTNQPGVRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UXZ5</accession>
    <name>A0A832UXZ5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L15e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_00705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_L15e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="PTHR11847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="158"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="189" mass="21976" checksum="CBDBEAE9B8034687" modified="2021-09-29" version="1">MGYYKYMREAWKKPNVELQRKRYLKWRAEQRFTRLEGPTRIDSARSLGYRAKGGYIIVRTRMTKGGRKRPAPRAARKPTSYGRFVTPGKSLQSLLENRVSRKYPNLEVLNSYWVGDDGKNVWYEAILVDPYHPQIVADSRINWICSNKHKKRVYRGLTSSGKRGRGLHKKGYGVEKSRPSLAANKNRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UY32</accession>
    <name>A0A832UY32_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA primase DnaG</fullName>
            <ecNumber evidence="1">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dnaG</name>
        <name evidence="4" type="ORF">H1011_00930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a ternary complex with MCM helicase and DNA. Component of the archaeal exosome complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the archaeal DnaG primase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01029">
        <property type="entry name" value="TOPRIM_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00007">
        <property type="entry name" value="DNA_primase_DnaG_arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020607">
        <property type="entry name" value="Primase_DnaG_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034154">
        <property type="entry name" value="TOPRIM_DnaG/twinkle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="1" id="KW-0271">Exosome</keyword>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="1" id="KW-0639">Primosome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Toprim" evidence="3">
        <location>
            <begin position="172"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="273"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="428"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="273"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="489" mass="53612" checksum="CAB84C036BA2357B" modified="2021-09-29" version="1">MAKIGVAAIKYMVRAKISTTGVVERPDVIGAVFGQTEGLLGEDLDLRELQKNGRIGRIEVELETKDGKTEGKIEIPTSLSKEDTALIAAGLETIERIGPSNSTISVEAIEDVRSSKRDYVVGRAQALLEKLGADVPESQELSSRVRTAIKTGEIKDYGPDKLAGGPDVESASEIILVEGRADVLNLLKGGIGNCLSTGGTKVPHSLKDLCKGKQVSVFLDGDRGGILILKALTSLIDIVNVSVAPNGTEVEEITQKEILKALRSKVPLDVFLGRERSPRREAPRGHDRDRRRDDRRNGRGRDRDRRREDRPRPQIEITPEMESLDKLVTEDFRGSGDAFLLKKTGSKFKKAGSIPKGDLKEVIKNLSEGQYQGIIVDGPLEQTMVTEASDRGINFIIGSIKPRFLKKRPGVLAMDYTFLRHIIEKNRERSGSPNGFEAPKKAEAERKTLKPKPVAKDRKTEKKPAVKKSAMKRGKEGKKSASKSKSKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYA2</accession>
    <name>A0A832UYA2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="229" mass="25447" checksum="9AD2C8CBAE0C8995" modified="2021-09-29" version="1">MKVIIVMPAYNEEKTIKQSLQSLEAGFPGANVVVVNDGSSDKTEEIALKEGAFVASHIINRGLGATLATGINSAIRKNADIIVTFDADLQHSGRDIKNLIEPIQKKRANAVIGSRFLRTEDLEMMPPVTKFGNWFLTGFTNLLARTKVTDSQSGLRAFDKKAAKAISIVCDRYDVSSEIVYELGRCGMKIEEVPIKALYDERSKRKGTNVREGVKIMYGILLKRLWLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYE6</accession>
    <name>A0A832UYE6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Elongation factor 2</fullName>
            <shortName evidence="7">EF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fusA</name>
        <name evidence="9" type="ORF">H1011_01865</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_A">
        <property type="entry name" value="EF_G_EF_2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004543">
        <property type="entry name" value="Transl_elong_EFG/EF2_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00490">
        <property type="entry name" value="aEF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="19"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="28"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="94"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="148"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="Diphthamide" evidence="7">
        <location>
            <position position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="734" mass="81523" checksum="DB2BC0D963345AE5" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYF7</accession>
    <name>A0A832UYF7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="174" mass="20372" checksum="27F6308C8B4FAB60" modified="2021-09-29" version="1">MADYKDSVIYERYTRSFQALITTNFSIKTREWMIVPVGDDEEHHYKWLASSYFVRDLCNDATTSAQYGFYTVLPYLTMMWEEGELNVSTVRKRLDGKSWRVLFRSGVVRDDTDQSRLYTRLKSGLARQLGTAYEIIEGIEEAGKGFVINNELRHKLEEKLSDDNLRKSGVFKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYT4</accession>
    <name>A0A832UYT4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oligosaccharide repeat unit polymerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002760">
        <property type="entry name" value="O_anti_polymase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01901">
        <property type="entry name" value="O_anti_polymase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="345" mass="38394" checksum="F70A3714B0F4D46F" modified="2021-09-29" version="1">MKNDEARLDIFFRPSVLLSILTFLFLLASSHSISLISLSFVVLCLLMFFVGELLGIRSFKQKVVKKSLPQALKIAYWMYAVSIVSLHLNFYASGGIPLLQPAIRQFMNPLLTTLSFLIVPAALLLMVGYSEHRKSKIRMLAIFAVTLFLISLTGFRTEVMVFLFSTLLVLRYTGIVSTKQVMQLGILAVLFFFALTLLRTGSFDSNRISSTVSAYDFVVSQSDLTGYTKGFVQFADFIDIFSSFPIYGGRTLISSLIGVRSGVSTTSMLYGPPYADFGFVGSLIFLFFGWVLGFGYKAASKGSGYAILHSLVLVFLLIGIETGIVDLIVWLYFIAAFSYYKYNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZ20</accession>
    <name>A0A832UZ20_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000005">
        <property type="protein sequence ID" value="HIJ99352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="167"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="259" mass="28281" checksum="999325BB1B92F284" modified="2021-09-29" version="1">MAILKKKKSDYDPLEDLPPEKEKLKSQSAGADIESIKEEVGFPEAPEEEAPLEAMPPAPPVPPAPEAPQSLQAPSEAPPSETGQVPEFIQPAPAGQEAQPQEEDPLAFLGGAGDLEAPQEEGQEMPPAPTSELPQVPPKTEFQEAPLPAPTDPSYDSIIRNETEVIRREFETKMSLLKDEIQSLKKLDEEIKGVVEAMDRIEQKYEKVETRAEDNNTLLTETLNDVKSTVSAIDKIMSSALPALIKEVRSISEIKSKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZC0</accession>
    <name>A0A832UZC0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDP-mannose 4,6-dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="2">
        <location>
            <begin position="5"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="246"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="310" mass="34125" checksum="CC1A7D5FF8D926D0" modified="2021-09-29" version="1">MAKAIVTGAAGFIGSTLSDTLLEQGKDVIGIDCFTDYYERSTKEKNLESSKTCENFSFLELDLAEADLSDAFSGVDVVYHLAAQPGVRYSWENFDVYLKNNIKATQRVLEAAKESGSRVIFSSSSSVYGDAELPLTEDTKARPVSPYGASKLACEHLCRIYSESFKVPTVSLRYFTVYGPRQRPDMAINIFTHKILAGEPIKIYGSGEQTRDFTYVQDIVDGTIAAGESSLSNDILNIGGGSQIMLNDLVSKIEKALGKEAKIEKEESQRGDMKHTKASLEKAKKDLGYEPKISIDEGIKRYTDWVVSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZE9</accession>
    <name>A0A832UZE9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_00090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="305" mass="34458" checksum="1B287BD389B455EF" modified="2021-09-29" version="1">MKPAISIQNLVKNYDSVEAVKGISFDIKKGEFFGLLGPNGAGKTTTINAITGLVNISSGQVKVFGHDVIKDYRETRKRIGLSQQDLMSLDRFLSVEGILTYQAGYFGIRRYEAEKRAEELLEHFDLTSKKNVDIRKLSGGMKRRLSIAKALVHDPDILILDEPTAGLDVELRVDMWRDLRKFVKEGKTVLLTTHYIEEAERLCKRVGIIDHGRLIELDTTKNLVDKLSAQRITVVVSGTIRRLSTPLKKLGVSVKGNRMRIYIDGDYSKVGKALYEIEKMGLKIIEIRTAENRLENVFLRLTGHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZG0</accession>
    <name>A0A832UZG0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="151" mass="16233" checksum="5A173149D5106F6F" modified="2021-09-29" version="1" fragment="single">MKTQMRKAQGGLPFGASLIIAIVLSLIGAAFIFNMGGQIFGVVKSVPTEGSEIVAIARDGGVCLQRPSSELYEDYIVDYDIDELTFTTGALQFPPDYFEGNSWFQGICELSNTEDLCEYDEWGIITGGGSLPSVSGQPCEWKDLGGGSFIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZJ7</accession>
    <name>A0A832UZJ7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="117" mass="13600" checksum="0452DF5D1568BF0F" modified="2021-09-29" version="1">MSSKQKVSIVDMHLLRDPRFSKLNKNIAPVFTRTIDGEFIPDDKKLRLLLLIEKWVENNPEELSSPVEGSEMEVGDFLEGVSDVVNNIPSMDPQTVKAWKTLRAKNRRRRRKRNPRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZL4</accession>
    <name>A0A832UZL4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exosome complex protein Rrp42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_00740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_PH" evidence="2">
        <location>
            <begin position="31"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="3">
        <location>
            <begin position="177"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="250" mass="27107" checksum="B57A2DA5A11C3986" modified="2021-09-29" version="1">MSRAIVSKIEKENVLALAEEGKRLDGRKFDEIRPITIETGLYARAKGSANVKLGNMEVAAGVSIGTMEPYPDSPDSGTLSVTAELTPLSYEHFSMGPPSDDDIELSRVVDRGIRESKAIEMDKLVVESGVEVRSVFVDLWTLNYAGNPIDAASLAGVAALHNAEDEELGKLPVVKKPIANTFIKIGEHILLDPSLEEEKALEARFTVTLEDTGNVCAMQKAGSSNWTTDEILACVKIAAKHSKETRKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZR6</accession>
    <name>A0A832UZR6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF106 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_02565</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038978">
        <property type="entry name" value="MJ0935"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42198">
        <property type="entry name" value="PTHR42198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="35"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="151" mass="17385" checksum="A589F8C714E2A2DA" modified="2021-09-29" version="1">MSILASPMYFIMVVSAVLTLTLSIVNKVFTDPDRMKEIQAAMKSYNKELMAATRAKDNEKIEKLQKDKPKISQMQQEMMKMQKPIFLSMIPFLVVFYFLGKLATGQGWGEFIQLPFTISLFSVGNDLTWIGWYMWCSLPFTMLFRKALGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V047</accession>
    <name>A0A832V047_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="62" mass="6973" checksum="2847D07769D2A22F" modified="2021-09-29" version="1">MKYKIIALLIVLAVLVSGCTAMDGVADEISEEEEQERQDIEELFEDDLDDALGDLDELEELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V050</accession>
    <name>A0A832V050_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Proteasome assembly chaperone family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000502">
        <property type="term" value="C:proteasome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004426">
        <property type="entry name" value="CHP00062"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00162">
        <property type="entry name" value="TIGR00162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0647">Proteasome</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="280" mass="31149" checksum="F5583EBA4CF51AD1" modified="2021-09-29" version="1">MIPRTSTENIGDRHEQMETFVKYRKKPKLNNPVLIEGLPGFGQVGRLVAEHLVKEFKGEKFAELYSPHFPPQVMIKNDGLIDMISNNFFAIKRPKKRDILVVIGESQAATITGQYEICEKILDVAKEFGVKDVITVGGYAMGRLMKRPKVYGAANDKKVIKEFSKLGAIFKTKGDRGGIVGASGLLLGLGQLRGMSAVCLMGETPGHPLLIDAKAAEEVLNIIGAYLGEDIPMGELDKRAKELEKFRLGLEKMMKKAIQQVERQEESEQKKTEEKVKYIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V089</accession>
    <name>A0A832V089_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Segregation/condensation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="225" mass="26408" checksum="D2176FD669F716FF" modified="2021-09-29" version="1">MELNLDQILQSERAWEYVLLDIVRSENLDPWDIDISRLTAKYTERINQMKEFDLKVPARLLLAAAILLRMKSDRLVDSEEREAYAELLRGDEEFLFGDDDEESGPSEEVPLLTLITKRKHLRKITLEDLIGKLEVSMRPKERKVKVEPFVLVFDEVDITEQIEELYTKIMESKKDKIPFDDLLPSKTREDMINTLMPLLHLANDSKVKLVQEKLFEDLYVLSEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0B2</accession>
    <name>A0A832V0B2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDCD5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002836">
        <property type="entry name" value="PDCD5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01984">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015730">
        <property type="entry name" value="TFAR19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="SSF46950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="109" mass="12671" checksum="457F5933EE25474F" modified="2021-09-29" version="1">MDDSELEKIRRQKLTEMQAASEQEEVRAYQEAQAKNQVESVLKLILTQKAWDRWNNAKMANQNVAYSAAMSILQQTRGKVTQKISEEELKKILSQVASSQRREFNITRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0C5</accession>
    <name>A0A832V0C5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="9">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cysS</name>
        <name evidence="11" type="ORF">H1011_02945</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="9"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="10">
        <location>
            <begin position="355"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="266"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="494" mass="57282" checksum="BCEB6F3372929605" modified="2021-09-29" version="1">MRQRIYNTLSGKKEDFKPRKRGKVHMYVCGPTVYDYSHLGHARAYVAFDVIRRYLEHSGNEVIYVNNLTDVNDKIIKRAEETMDTPESVAERFSDEFFIDMDALGVKRADFYPKVSEHMQEIIGMVAGLIEKGYAYESAGDVYFDTSKAKDYGKLSRQKMGKILAGARVKPNKKKKTQADFALWKNAGENEQKWKSPWGQGRPGWHIECSAMAMKYFGENLDIHAGGQDLVFPHHENEIAQSEAYSGTQFAKYWMHNGFVTVDREKMGKSLGNFFTVREILKKHRPEVVRYFLLSTQYRKPIDFTDKSLAEAKSSLEGIENSLANLKHAITIKQGSKKTKEDKEVLKKVEYHRKQFFAAMGDDFNTREAISSIHQMCTVLNAYLAEKPNNEVLRESLDSFEEFSQILNLFEEKDIDQDEEIIAHLRRLMRELEVKKLKDDYTVSGLMRLVLLEREKARKENNYESSDKIRESLSHMGIVIEDTEEGPRWQLRRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0E7</accession>
    <name>A0A832V0E7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_03105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00796">
        <property type="reaction ID" value="UER00771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033320">
        <property type="term" value="P:UDP-D-xylose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="PTHR43078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="7">
        <location>
            <begin position="7"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="312" mass="34779" checksum="98D5BA0CFA7C1214" modified="2021-09-29" version="1">MAKQKILVTGGSGFIGSHLCDFLLGKGNDVVCVDNFFTGTKSNVEHLLENDSFELLEHDIIEPLEMEVEQIYNLACPASPVHYQENPVKTVKTSVMGMINMLDLAQSSNARILQASTSEVYGDPEVHPQPETYNGNVNPLGPRACYDEGKRVAETLMMDYHRENQVDIRIARIFNTYGPKMAQDDGRVVSNFIIQALTGKDLTIYGDGKQTRSFCYVSDMVLGLYEMMNQNNIGPINLGNPHEITVGDLATEIIELSDSISQVIFKELPEDDPKQRQPDISLARELLGWAPQVSLKEGMSLTVKYFREVLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0E9</accession>
    <name>A0A832V0E9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="166" mass="19661" checksum="7CE41AAFBF77049A" modified="2021-09-29" version="1">MSEKLLQWVDSTETVPRKGDFILFMRGNSLHKGVVEMCGDDFIKLSKMWIWRKMKGRRLEEFIENPGKDMDKLWKGSRWEMYAGGEELPRGIEYIVVGLPEINYMEEYVGKKVLVYSFKGRNLVSFKGKYIRSELVKNSFIFKLKKQIIPVHFEELIHIRKTFMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0F7</accession>
    <name>A0A832V0F7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="76" mass="8608" checksum="E4BE4960559CD5AA" modified="2021-09-29" version="1">MVRKSKKTKEEQRVMFAVEEIVLSFVGALVLAFGFVVISTAEGSTFWANFVLGLFVIWLGLLLFTVPLIRKIEELM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0N7</accession>
    <name>A0A832V0N7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">30S ribosomal protein S5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsE</name>
        <name evidence="8" type="ORF">H1011_02590</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_S5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="7">
        <location>
            <begin position="129"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="283" mass="30946" checksum="01CFEDE283A54481" modified="2021-09-29" version="1">MSEEKTPAEKKVEIKTEKKSEETKAPAKKESTTPSTGKKEAPAKKESTPPSTEEKPKTSAQTSGNRRSKFGRPSTIDLENWKPKTELGREVLAGNYESLDSIWDNAKVIREPEIVDFLLPGLEERILKIGKGQRPFKWVQRMTDSGRRSKYFVAAAVGDKNGYVGFGIGRAKDFGGAISQAMRRARLNLTKVEFGSGSWDEASSEGKHSIPYKVTGKCSSVSLDLLPAPKGTGLVANKISSDLISLAGISDLWTKSRGHTKTRVNMAAATFNALKKLSKDNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0P6</accession>
    <name>A0A832V0P6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps3</name>
        <name evidence="10" type="ORF">H1011_02665</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Binds the lower part of the 30S subunit head.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_A">
        <property type="entry name" value="Ribosomal_S3_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027488">
        <property type="entry name" value="Ribosomal_S3_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_S3_euk/arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="9">
        <location>
            <begin position="17"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="207"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="207"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="222"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="256"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="293" mass="32026" checksum="857A841F1B309DEC" modified="2021-09-29" version="1">MAIERKLIKEAIDKVRVKKFVLDSLDNVGVGSVDVKRTPLGTRIIVTAVKPGLVIGRKGKNIQMLTSELSKRFKIENPQIEVQEVEVPEFNPAIMAEQLVSTIERGIHFRRASHSLIKRIMGKGALGVLIEISGKLSGERSRKEKFMAGYIKYSGETALQSVSMSVKQAKRKAGVIGIKIRLAPPADPVKLAALVFDDSHIVSESIEMNGKKSEDELQKLQDSISDSSNESADASSSKPDLTKKELSKVKKAKAPKKAVVKETKAKAPKKAVVKETKAKTESGKTNEKTEGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0T7</accession>
    <name>A0A832V0T7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="203" mass="20999" checksum="6FBD6F1C3C7B358E" modified="2021-09-29" version="1">MQGKIKTNIAILAIIPTAIIVIMLILSSIGSFNISLSGFTTAGSNNTTLMASVNVSETITLSLSAATINFGALVQGTANNTTNDAPNPFVLVNGGNIGIDLTIKMNQSPFSGTGSGNNTNTFRFKAGNCSTIVCGTGNSSFFNWGTSQTNFQNFTTVNQNLIKNLSYSSGNDVAEAEILLSVPSDESTGSKSVSITFTASKTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V199</accession>
    <name>A0A832V199_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Malate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_00015</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the LDH/MDH superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01339">
        <property type="entry name" value="LDH-like_MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011275">
        <property type="entry name" value="Malate_DH_type3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="6">
        <location>
            <begin position="1"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="7">
        <location>
            <begin position="145"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="302" mass="31923" checksum="85F24AC4350E78F0" modified="2021-09-29" version="1">MKISVIGTGNLGSEIAFMLAQKGLGDIVLLDINKELAEGHQMDIEHASSGISYGGTVNSASSSEEIAGSDLVIVTAGAPRQPGMSREDLLAGNATIIKSVCADIKKNAPDSIVLVTTNPSDLMLMLVLQETGFSSKRVLGLGNLLDSYRLRSLIAIETGKNLTEVEAIILGQHGDRMLPVLSSCKVSGKPLSELLDSDKISKIFERTKSAASELISKKGATVFGPAAATIELAESIVKDLKKELPVIALLKGEYGLSEVCMGVTGILGKSGLESISELDLSDSEKKTLQETSDFLKKKFSEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1B3</accession>
    <name>A0A832V1B3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Regulator_TrmB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021586">
        <property type="entry name" value="Tscrpt_reg_TrmB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11495">
        <property type="entry name" value="Regulator_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Regulator_TrmB" evidence="2">
        <location>
            <begin position="13"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="270" mass="29308" checksum="8AC9203F1B3F6F69" modified="2021-09-29" version="1">MAKSSPDLYRKVLLLIIAVFFFAVVFKVILAEESTLEFTGANIYRAVYAQQLISNAGFASNLQVEGTWRSTGEQFSDEGRILSASKGVFTILYNGRQVLVGGPSTGSEDISAKALRIVVQNADVIRVGVEPIYGDDFSFFTSSLASIPIKLAGENIMETSLSGSVSVDSVDTISPTIAQDLENILGFGSSVTIYDKGLTIFLDGVLLKTLEELSSYFSETGILLSRVSSSRLELDVRTVSDSNLSETELSSRAPASFDYYMLRVIDEPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1H5</accession>
    <name>A0A832V1H5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase sliding clamp</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Proliferating cell nuclear antigen homolog</fullName>
            <shortName evidence="3">PCNA</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 8" type="primary">pcn</name>
        <name evidence="8" type="ORF">H1011_00595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022659">
        <property type="entry name" value="Pr_cel_nuc_antig_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PTHR11352:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00590">
        <property type="entry name" value="pcna"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01251">
        <property type="entry name" value="PCNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCNA_N" evidence="6">
        <location>
            <begin position="7"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="PCNA_C" evidence="7">
        <location>
            <begin position="122"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="248" mass="27363" checksum="1DDFCEBBD1B98980" modified="2021-09-29" version="1">MAFKFILDEPDLLKDCVIASSSLLNEAVLTVDSNGVSLVSMDSANVALVEFNILAGAFRELEASEKTEFGVNMSDLVSVMRRVKSTETLEMSMDDGMLSIKISGNAKRAFQIPLIDVKKETKIPQLEFPASIEIKTEFLEDGISDAEIISDAVIFEADPDSFKIRSRGDNRTAELQMQKGEDGIVSLEAKDHVKSTFSLDYLKKMIKASKISDVASIKIGNDYPLRMTFTVLDKAHIGFVLAPRIEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1Y1</accession>
    <name>A0A832V1Y1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="447" mass="51519" checksum="62BCAC18B1F1ACCC" modified="2021-09-29" version="1">MRKYLKRPKVGMEVELFTLDNTGTPVPAVDRLIKNCPVQKRQYAIQREYAKHLLEIGAFPTIQVRNLALSFLENLEAVAETAEELDLLLYPLGTYPGKFTSEVRRDYSYVTKEKVIGEPFKNIAPKVAGFHFHYGLPRGILNRSTYELRMTKNSGAREAFLSEYNFLIAADPALTTFMQSSPFFEGRLLGKDSRTLLYRDMKTKVNDEIIRGIYREERTFGRIPRYANTTADLNFLVEKRRSSWEALMKDVGMSYKKISLRKNPLDLYWGPVRINKLGTLEQRGMDMNEPKYVVGMAILLRHILRQINKMELKVKASDVGAYKPFKLEGDTIHIAPFSKVKNDLQYKSAVDGLEDKEILNYCRSFYRLSKKFIKHDRSLALKAIKNMLKTKRTKSDMVIRAAKRKGYSGDSELPQEVAAEIAIKYSKKFITEIEKTKSDIKNISLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2L2</accession>
    <name>A0A832V2L2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Vitamin B12-dependent ribonucleotide reductase</fullName>
            <ecNumber evidence="13">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">H1011_03545</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the ribonucleoside diphosphate reductase class-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="13"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02888">
        <property type="entry name" value="RNR_II_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013344">
        <property type="entry name" value="RNR_NrdJ/NrdZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="SSF48168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02504">
        <property type="entry name" value="NrdJ_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="11 13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="13" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="7 12 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 13 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="14">
        <location>
            <begin position="8"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU364064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="HIJ99861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="683" mass="75525" checksum="0AAB74F06EE94502" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2P5</accession>
    <name>A0A832V2P5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000019">
        <property type="protein sequence ID" value="HIJ99906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="297" mass="31710" checksum="2CDF510F647816D2" modified="2021-09-29" version="1">MKHSRVLPLILLLLVVSISGCAGKDTEALPSGDGVAVRSFQSDFGDVYSGESASITLVAENRGDFTASNVKAKLIRSGSFTNTTALEITGSNLGIPLGDTYASDAFFWELDAPTILQDRSEEVQAEVSYDYKSSAVSTVHFVPNYVLRETGLGAYPDASSSSRSPIFIDIVANQPVQVRNTGSMTVRFTVILVNKGGGKVESLGTGINSSNKKGDCTQAFGCIDNITVRGLGPGCTGFNKDVTGVKLIQGKEGRKNFDVTYNIIDDSVSTSCQLQVTAEYRYKLLSPIESLMVLKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3N3</accession>
    <name>A0A832V3N3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Prefoldin subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">GimC subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pfdB</name>
        <name evidence="8" type="ORF">H1011_00760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 7">Heterohexamer of two alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00307">
        <property type="entry name" value="PfdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012713">
        <property type="entry name" value="PfdB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02338">
        <property type="entry name" value="gimC_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="116" mass="13297" checksum="0C44C47F8963F108" modified="2021-09-29" version="1">MSEETKNTLREFQEYQQQLRMILTQKTQLEMRFAETKKALDEISKHNPSEVYKIVGQVMLKTDSDKAKKGLDDEAEIIDVRLKSLKKQETSVNNKLKAIQEKLEGSFKPPAQGGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3P7</accession>
    <name>A0A832V3P7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histone family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_00910</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Chromosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal histone HMF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003958">
        <property type="entry name" value="CBFA_NFYB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00808">
        <property type="entry name" value="CBFD_NFYB_HMF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="SSF47113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0158">Chromosome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBFD_NFYB_HMF" evidence="5">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="66" mass="7345" checksum="3DD9138D9E5E822C" modified="2021-09-29" version="1">MAELPIAPFERLLKKAGAGRVSEEAAERLRDTIEEQTLDLARKAVSYAIHAKRKTVRKEDVALAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3V3</accession>
    <name>A0A832V3V3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choice-of-anchor D domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_01535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000008">
        <property type="protein sequence ID" value="HIJ99489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="996"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="4">
        <location>
            <begin position="52"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1048"/>
            <end position="1087"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="1121" mass="119012" checksum="3B200CCB5C743BA4" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3X6</accession>
    <name>A0A832V3X6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF357 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000011">
        <property type="protein sequence ID" value="HIJ99549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036809">
        <property type="entry name" value="AF1782-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023140">
        <property type="entry name" value="DUF357"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04010">
        <property type="entry name" value="DUF357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158372">
        <property type="entry name" value="SSF158372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF357" evidence="1">
        <location>
            <begin position="14"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="85" mass="9224" checksum="210FE0BBCBC5CD6D" modified="2021-09-29" version="1">MELTPKYVQGLIEKTSKALESLEVLEGGKAVYDMALSYRDDAKHFAEKGELVTALAAVEYSHGLLDGAVGSGAMKVLENEELFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3Z3</accession>
    <name>A0A832V3Z3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">30S ribosomal protein S28e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_02105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_S28e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="PTHR10769"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="113" mass="12417" checksum="F4329940236B399C" modified="2021-09-29" version="1">MAKKDAEPENQELKEKPKKDSKEEPKTGSKTKSKKGSKQEVIPLAAESSIPARVTEIMRRTGATGGIIQVRAEVLDGRDKGRVVKRNVKGPIREGDILLLKRGLMDVGDIRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V440</accession>
    <name>A0A832V440_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Preprotein translocase subunit SecY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">secY</name>
        <name evidence="12" type="ORF">H1011_02575</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019561">
        <property type="entry name" value="Translocon_Sec61/SecY_plug_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10559">
        <property type="entry name" value="Plug_translocon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="114"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="403"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Plug_translocon" evidence="11">
        <location>
            <begin position="36"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF10559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="470" mass="50113" checksum="F137CA6411856611" modified="2021-09-29" version="1">MSFQKILQNLPSVAKPSKTLSFKQKLKWTALPLISFFILGEVALFGLEAGAAGGDIFGSLRAILATSFGTVLTLGIGPLVMGSIILQLLNGAGVFKFDMSTPEGKATYQGAQKVLALAFTIFEAAVLVISGQIASSAILAASKGLLFANSIVIAQIILGGIIIIYLDEVVSKWGFSSGISLFIAGGVSLEIITRSLDPFRLGPGQPINGAIPAFISSLVEGSIQFIRVHPNDMLALFATIIVFVVTMYAQTLKVEIPISYGRIRGFARRYPLPLVYASNMPVIFIAALIANLNFWVAMLNKAGINFFGYFDPAGGSHGFIFYISPYTSFAKDLIQRNVGSLDLLHAFTYFLVVVLGSIMFSKLWVGISGTNSKALAEKLVKSGMQIPGFRTDARIIEKVLDRYIPSLTILGGAFVGALAAIAEFSGALGGGTGVLLTVGIIYQLYQEIASEQLMEMHPAIRGFLGEGGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V4A0</accession>
    <name>A0A832V4A0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="158" mass="18041" checksum="61F626BF6962440C" modified="2021-09-29" version="1">MTGLIQYIGAAAGIVWIIHYIFYQQKEVIIHWEMTPRRMFYVVSHIIRKYWVKLVGKLVAKELLVGEAAFIGRGLTGRLSARYGTTVVGTDVAAKTGFISMNPQTMLIFLLLFFVIIELGLAYRSNKNIFREYKSLGKIGLEIFIIYSFADILATMMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V4B3</accession>
    <name>A0A832V4B3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">50S ribosomal protein L37e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpl37e</name>
        <name evidence="12" type="ORF">H1011_03485</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10 11">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 11">Belongs to the eukaryotic ribosomal protein eL37 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00547">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_L37ae/L37e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001569">
        <property type="entry name" value="Ribosomal_L37e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018267">
        <property type="entry name" value="Ribosomal_L37e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01907">
        <property type="entry name" value="Ribosomal_L37e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01077">
        <property type="entry name" value="RIBOSOMAL_L37E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 10 11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="8 10 11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7 10 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 10 11" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 10" id="KW-0863">Zinc-finger</keyword>
    <feature type="zinc finger region" description="C4-type" evidence="10">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="53" mass="5965" checksum="7BF9AFFDCBA0AD6F" modified="2021-09-29" version="1">MGKGTPSRGKHNKRTHIRCRRCGKHAYHATHEVCASCGFGKSAKLRSFAWHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V7T7</accession>
    <name>A0A832V7T7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor E</fullName>
            <shortName evidence="4">TFE</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">TFIIE subunit alpha homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Transcription initiation factor TFIIE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tfe</name>
        <name evidence="7" type="ORF">H1011_00125</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.</text>
    </comment>
    <comment type="domain">
        <text evidence="4">The winged helix domain is involved in binding to DNA in the preinitiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TFE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01909">
        <property type="entry name" value="TFE_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016481">
        <property type="entry name" value="TF_E_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017919">
        <property type="entry name" value="TFIIE/TFIIEa_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002853">
        <property type="entry name" value="TFIIE_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024550">
        <property type="entry name" value="TFIIEa/SarR/Rpc3_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02002">
        <property type="entry name" value="TFIIE_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00531">
        <property type="entry name" value="TFIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51344">
        <property type="entry name" value="HTH_TFE_IIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH TFE/IIEalpha-type" evidence="6">
        <location>
            <begin position="129"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="20"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="288" mass="33350" checksum="FD7363E943A3052F" modified="2021-09-29" version="1">MARGIKTMRTRLKKIIKTSKRKNAIAVKSSKTLKSSSVKSPVKRMKVSPRKKSPSKTVKKTSSRKAILRKVSVKGAGPIRKISVKKIAVGTSKKIIVRKKKTEAEKAKIKVLAKKKLKKIRANRPDFLEDKKYNEFLLSVVGEEGIEVAENVSFEEISDVELAEGMDLKANIIRKYLYALYEVGVVTYRRHRSKTGWYTYYWKLHPERIDMALNEIAGKDINYYETELRQERENQFFTCKNREECGRVIFDHALETEFRCHKCEKKLEFTDNSNIIEGLEKDLARLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V7Z7</accession>
    <name>A0A832V7Z7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transcription factor S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_00615</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019761">
        <property type="entry name" value="DNA-dir_RNA_pol-M_15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001529">
        <property type="entry name" value="DNA-dir_RNA_pol_M/15kDasu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006288">
        <property type="entry name" value="TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="PTHR11239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="TFIIS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00661">
        <property type="entry name" value="RPOL9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01384">
        <property type="entry name" value="TFS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01030">
        <property type="entry name" value="RNA_POL_M_15KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="8">
        <location>
            <begin position="61"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="103" mass="11787" checksum="0BC7723267B42341" modified="2021-09-29" version="1">MKFCEKCGSLMKPNDSGSEFLCDCGHTESVGEGHITTEKMEKGIPDIVVKEEGDKILLPETDADCECGNKKAYYWMEQTRSADEAPTRFYRCTKCMHTWREYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V857</accession>
    <name>A0A832V857_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Winged helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_01075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="3">
        <location>
            <begin position="111"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="10"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="201" mass="23299" checksum="701752FD73B155FF" modified="2021-09-29" version="1">MGLLDLFRPKKKKSVKKASGKGKLRKPSRQKRLQSKATQKPLQSRQLSKKRANLVVIDPGIEVKPEIEDPLISISRQLTKIQDALEKSHRTMQSGMQSLRDDHHTIIERQVTPDNVAEAFENRKHELEQQKENIEDELDILEIDQKILDSLNEKKLRSITISEELNLSRQYTASRLSHLIDSGFVKRTKRGRSVYYTLNKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V861</accession>
    <name>A0A832V861_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_01155</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08768">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="57"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6_C" evidence="5">
        <location>
            <begin position="307"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="69"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="397" mass="44853" checksum="29593EA9988B3F24" modified="2021-09-29" version="1">MKQKTLEDLFDSFLSKQSFFISKQALQDTYTPDTVPHRNEQINQLAAILAPGLRGERPSNVFIYGKTGTGKTLVSKFVCQELESKAIKQNTPLKTLYMNCKMEKINTPYRLLARFLSFIDIEVPPTGLPTDEIYKIFLREINKVGGIFTLILDEIDTLVETDVLYNLTRINTELTNAKISIIGISNDLNFTNNLDPRIKSSLSEEELVFPPYNAIQIQDILLDRAKIALSPTSIGEGTIAKCSALAAQEHGDVRRALDLLRVACEIAERNVDIKVNEKHVDEAMRKIDIDRVVEIVKTQPRQSQIVLYSIIYLKELNKNEVATGEVFEVYHNLCKQIGLVPLTQRRVSDLISELDMLGVINSLVVSKGRYGRTRKIKLDMTPIALEKTSEILRGELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8D6</accession>
    <name>A0A832V8D6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DegT/DnrJ/EryC1/StrS family aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="376" mass="41774" checksum="50EDAF2A34F515A3" modified="2021-09-29" version="1">MKVPLFKTYWNQEDIDSVKTVIERGTYWATGPEIEEFEKKIAEFVGTKYCLAFNSGTSALHTLLLVHGVKEKEVIVPSFTFIATANAVVLAGGIPVFAESEPETYGLDADDVESRITEKTAAILNLDFGGFPARDHEKLREIADRHNILYIGDSAESLGSSINGKMLGSIADSTIFSFCQNKVISTGEGGVIVTNNESVYEKAKLIRSHGRVELADDYFSSTEDNDYIQIGYNYRMPTMCAALGISQMNKISENIKMRRTNAEHLNLGLGKIKNVKTPVLIEGHLQVYQMYTIQLNDKSTRDALQNHLSKNGITTKVYFNPVHLKTVYKNMGCSEGDLPKTEALSGKVLTLPMYPSLTEAEMDHIINSVEEFFNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8J7</accession>
    <name>A0A832V8J7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L24e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpl24e</name>
        <name evidence="6" type="ORF">H1011_02110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00472">
        <property type="entry name" value="Ribosomal_L24e_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00773">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023438">
        <property type="entry name" value="Ribosomal_L24e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_L24e-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10792">
        <property type="entry name" value="PTHR10792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TRASH" evidence="5">
        <location>
            <begin position="4"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="65"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="4"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="112" mass="12834" checksum="BFB7CC878479F878" modified="2021-09-29" version="1">MERCSFCGTEIERGTGKILVKKDGTLLYFCSSKCEKNLIKLGRNPVKFGWTRKYQKAKGRIDIAAEVRAKSEAQPKKEKGKPPSPEAEVVKKKSEEKKEDKKEEQKEEEKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8P8</accession>
    <name>A0A832V8P8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">tRNA-splicing ligase RtcB</fullName>
            <ecNumber evidence="9">6.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rtcB</name>
        <name evidence="11" type="ORF">H1011_02500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP + H2O = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:68080"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP</text>
            <dbReference type="Rhea" id="RHEA:68076"/>
            <dbReference type="Rhea" id="RHEA-COMP:10463"/>
            <dbReference type="Rhea" id="RHEA-COMP:13936"/>
            <dbReference type="Rhea" id="RHEA-COMP:17355"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:83062"/>
            <dbReference type="ChEBI" id="CHEBI:138284"/>
            <dbReference type="ChEBI" id="CHEBI:173118"/>
            <dbReference type="EC" id="6.5.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8 9">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 9">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the RtcB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.-" evidence="9"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="PTHR11118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="8 9" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="160"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="GMP-histidine intermediate" evidence="6">
        <location>
            <position position="395"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="197"/>
            <end position="201"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="320"/>
            <end position="321"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="369"/>
            <end position="372"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="395"/>
            <end position="398"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00033766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU371113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="472" mass="52337" checksum="F12645C97F2233B9" modified="2021-09-29" version="1">MKKESENTYVFEKKGDMKVPLKVFASEKLMKDIEKDRALEQGINMAKLPGICKHAIMMPDAHQGYGFPIGGVAAFDAEKGIISPGGIGYDINCGVRILTSNLGVDEVREKLEEILNVLYENIHTGIGSESKIRLETSELEELLDTGIDWAIKKGYATEEDKERCEENGRMPQADSSKVSDRAKKRGRKQVGSLGAGNHFIEIQAVEKILDKSTAEKFGIKEEGQVVIMIHSGSRGLGHQVCTDYLRRMETEQPEIFKSLEDKELIYAPLGTEIAEDYYKAMSAAANFGWCNRQVMTYETRNSFKKVFPDSDLKLMYDVCHNMAKLETHEIDGKMKKVYVHRKGATRAFGPGHKEIPEIYRDVGQPILIPGSMGTSSYVLVGTDEGMKETFGSTPHGAGRLMSRHQANKLYTGEQVQKDLKSKGILVRSASWRGVSEEAPGAYKDIDEVVKVSHEVGIGKIVAKLVPLGVLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8X0</accession>
    <name>A0A832V8X0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="144" mass="15863" checksum="1118BF84513A0E08" modified="2021-09-29" version="1">MAKRPRKDKGLVIFGVRMNPQAWVLIGLVAMFVFATLGYYITGSGDTGQANQDFVQAVVVFGMEGSVSRVITLEEGKSAIDLFREIASLNSDLSTVTVGNISKTSNSTHAWKYYVNGALRLDGPTSHFPLSGDYIELRMSKRFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V923</accession>
    <name>A0A832V923_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative snRNP Sm-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_03490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the snRNP Sm proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01731">
        <property type="entry name" value="archaeal_Sm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044641">
        <property type="entry name" value="Lsm7/SmG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="LSM_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022901">
        <property type="entry name" value="snRNP_Sm-like_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10553">
        <property type="entry name" value="PTHR10553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sm" evidence="3">
        <location>
            <begin position="7"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="75" mass="8460" checksum="BD66E7394F985883" modified="2021-09-29" version="1">MGERPFDSLNQSLGNTVILRLKDGKEIRGVLKAFDVHMNVVLEDAEETDTENTKRFGTLIVRGDNIIFISPNNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X4W2</accession>
    <name>A0A832X4W2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="147" mass="16584" checksum="519F4970ACA69282" modified="2021-09-29" version="1">MGFYNRKGSTAIFEQVCFAVMGVFIFVMFLTVFGGIKDDMSDFQAGHQFRNVASYVHLAISNSYIYGRYVDNYSLNIELPPYLAGRRYVIITNNTSILVRDEFYDINRTLPILKFNISINGSFSSTAGGQHRIAYNSTAGIMVLEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X4Y1</accession>
    <name>A0A832X4Y1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatase PAP2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="59"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="164" mass="18893" checksum="15F8AC521FDBBFF3" modified="2021-09-29" version="1">MLQELIAFDKSLFLYIYSLSGSTLPDFFFSAISHLADFWIWFIVLPIVYYYDGKEKNYFKLVLLGLIAIEFFTGFLKVSVERLRPLSAIATSFPSGHATRAFYIYSVLSLKMKNHAWILGLLAIFVGISRIYLGHHYPADVIFGALLGYYIGWFTLKYKDKLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X4Z5</accession>
    <name>A0A832X4Z5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000006">
        <property type="protein sequence ID" value="HIJ99359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="102" mass="11075" checksum="4050EF5351F861B0" modified="2021-09-29" version="1">MRNNKAVSLGINMLVILALAVFVVFLVSSFFFSEARESASGIRMISDLATEDKAEIGTMISDIPACYQAVDLGSECEDPVCCGLTYAQCKLAINEGCVWEIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X545</accession>
    <name>A0A832X545_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="275" mass="30266" checksum="22F97707EF0F74DF" modified="2021-09-29" version="1">MKRIFLGILICTVILSGQAYAALDERCSVESIGISSEYTNRLFVDIVYSFKCSAGASDEGQLTRARMHYGTRDIGNLILKDSYGELTTDTLPSDYEIDKGLRNSELGLVFRKSLEMTNYETNYILNVSFETGAIVSKADDGKLQAQPSDLIGNITGTSIRSTLESSDLGIGTISYSIKVPKGTVITNAQPDTCLVSGETVVCSGLDEDAFSEILVEWKQSEEVTQENSKLTEIADKVSTKIEELAKEVAEEETKEQVKGFLEKMKEKLSGLFDWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X563</accession>
    <name>A0A832X563_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">30S ribosomal protein S7</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_01870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005716">
        <property type="entry name" value="Ribosomal_S5/S7_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01028">
        <property type="entry name" value="uS7_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="6">
        <location>
            <begin position="48"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="200" mass="22210" checksum="C67844F11A6280E0" modified="2021-09-29" version="1">MDFKVFGKWDSTNLVVRDIGIKAYLNTGGNTVPHSYGKYAKVKFGNLHYSMVERLANKMMVTGHLKDNRTHKKNSGRDSGKKQMALKSVRKALEIVEKKTSENPLQVLIRAVEYSAPIEETTRIRQGGIIAHRPVNVAPIRRVDLALRFLSHGASARAFKKKQSVEASLAAEIISAGSGDQKCYSVSKRDELERVAASAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X569</accession>
    <name>A0A832X569_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">C1 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_01960</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Pept_C1" evidence="3">
        <location>
            <begin position="172"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="543" mass="59733" checksum="223D5157C2B8E6E3" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X597</accession>
    <name>A0A832X597_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PIN_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_02370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09876">
        <property type="entry name" value="PIN_Nob1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039907">
        <property type="entry name" value="NOB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033411">
        <property type="entry name" value="Ribonuclease_PIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814">
        <property type="entry name" value="PTHR12814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17146">
        <property type="entry name" value="PIN_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN_6" evidence="4">
        <location>
            <begin position="5"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="161" mass="17866" checksum="4B83655A684B6160" modified="2021-09-29" version="1">MTTYILDASAIQSGFEALGFSEDLFSTPSVIEEVRNKFLAYNLSLAVSLDKIKLEIPAENYINHVSETARKSGDRLSDNDIGLIALALKRKSAGRVRIVTDDYGIQNVSSLLGIDFLPMGTEGIKEIIEWVYYCPACFKKHSPSIDICDVCGTKIKRKKRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5A2</accession>
    <name>A0A832X5A2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribonuclease Z</fullName>
            <shortName evidence="8">RNase Z</shortName>
            <ecNumber evidence="8">3.1.26.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">tRNA 3 endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNase Z</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">rnz</name>
        <name evidence="11" type="ORF">H1011_02445</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="8"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02651">
        <property type="entry name" value="RNase_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="10">
        <location>
            <begin position="19"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="299" mass="33194" checksum="2771D993BF137341" modified="2021-09-29" version="1">MFSITFLGTSSGTPTVARAHSAIALQLNGEIILFDCGEGTQRQMMKAKTSMMKVRRIFITHWHADHSLGLGGLIQTMSLLGRTEALEIYGPSGTKKYMKSLLDVGHFNPKYQLRVNELKDGEKVEAKGYTVLAIDAKHSVPALSYRMDEPQKPGKFDRKKAESFGLKPPQFGELQRGNTQKVGRKTIKPSDVMGPFREGASFVYSGDTAYNEFLVKLSKKATVLVHESSFANDKKDFAKEVLHSTAEDAATVAKKAGVKSLVLTHISPRYLETDVLLKEASKIFKNTTIVKDFDKLEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5B7</accession>
    <name>A0A832X5B7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L19e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl19e</name>
        <name evidence="7" type="ORF">H1011_02600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_L19/L19e_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_L19/L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_L19/L19e_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015973">
        <property type="entry name" value="Ribosomal_L19e_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015974">
        <property type="entry name" value="Ribosomal_L19e_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="RPL19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="PTHR10722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="SSF48140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L19e" evidence="6">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="58"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="150" mass="17309" checksum="86268B441F7984D2" modified="2021-09-29" version="1">MKRRGEANTQRRLAASVLKIGQTRVWFDPEALDEINSAMTRGDVRKYIGLGYIKKRPKIGNSRGRIRKRHAQKAKGRQKGQGKRRGSANARLGKKSKWMVKIRGQRSLLKHLRDSEKISKTVYRKVYRLAKAGSFKHKAHLITYLRSKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5G6</accession>
    <name>A0A832X5G6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="77" mass="7972" checksum="58614E1C036752BB" modified="2021-09-29" version="1">MKETISIRSFSVLLIAVVFISVIGTTLVLQSLGFLSLPTSVDSGSATVSVTVVSPDSVVGIETTGEVKVDIITEEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFM7</accession>
    <name>A0A832XFM7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1512 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009995">
        <property type="entry name" value="DUF1512"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07431">
        <property type="entry name" value="DUF1512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016495">
        <property type="entry name" value="UCP016495"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="423" mass="47010" checksum="3698D892FBD793BC" modified="2021-09-29" version="1">MVIGIPADTSIWGTIVNWTILLIMFMYVLPKLYLYQIFSKLEMAAQKFEAISKKGQGLIVKKTAPFGRAKKDIRERVTRFVDFFIVPPVNLDPFGIIKKLDHVIDNSDTRFRRAADYIAPDADSEQKMNVFMGMQAAVMINMVAKIVRHYVEMTKKFKNLQFAMLLQMQLPMLEKMIESELKGLEAFLNGHAIGDGIGPMVIASQLDTEGKEIAKEAIATTKTVNGRRITFVKATGPGGRLGKIGEAVEKIAAKGKIARIITIDAAQKLEGEKTGTISEGVGIAMGGAGVQRYKIEEVATKYRLPMDAIAIKMSPFEAISPMPEKVVDSLNDAVDMLNERIAEVPKGQHIIVVGVGNTCGIPNTKKNLEKLVKILKERARKIKKAEKEKNKTWWGGTRKETEVWNFNRADILNLGKTAGFIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFT1</accession>
    <name>A0A832XFT1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoacyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_01430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PTHR12649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="SSF102462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="114" mass="12285" checksum="DFCE3326CF2FA778" modified="2021-09-29" version="1">MPHKQVIVVRKDLKLSPGKMSVQVAHASVESLWKSDGKVASKWSEEGSRKVAVYAEDEKQLLEIFEKAKSMGITVALITDAGKTEIPPGTKTAVGLGPDTQENLNKITGNLSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFU3</accession>
    <name>A0A832XFU3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dihydroorotase</fullName>
            <ecNumber evidence="5">3.5.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrC</name>
        <name evidence="5" type="ORF">H1011_01580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="5"/>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016812">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="4">
        <location>
            <begin position="52"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="425" mass="46527" checksum="7888047D090A4B6D" modified="2021-09-29" version="1">MAVDFVLENCKIARPDGILEASIAINNGRIQKIALSDAMPKADNAIDMSEKIVLPGAIDPHVHFRDPGFTEKEDFETGSLSALFGGVTTILDMPNTKPFTGTSEEFEKKKTLAEKKSYIDFSLYFGAMDGNIWEMRKVNPIGYKFYLDHPDIVGYSGLKAAASSLENKIFAVHAEDPDIMHDNLKKNSAADPKSHGKIRTAEAEMESVKAILNIEMGSNNLYFCHLSTPSSVKAVHEAGHFAELATPHLFLSRENSAELGNFARTNPSLKSEEDRLGLWKVLSLVSTLATDHAPHLISEKESASPPSGMPGVETFLPLMIDSVNKGFLDWTDVARLCSAGASNIFGLVNKGIIEEGKDADLVIIDRKKVWEIKASKLHSKCAWTPFEGRKLKGKIDSVFRGGKLAIDKGKLLAKPGQGKYIAPER</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFY1</accession>
    <name>A0A832XFY1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF87" evidence="1">
        <location>
            <begin position="40"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="452" mass="51150" checksum="C2AB5D9BC60ADA73" modified="2021-09-29" version="1">IPRHGSGIYELEESDFDILQLPKLDFAYVRSGSRKLDTKVGFEKDAYVTHWLISGWTNSGKTNSSKILLGVTLKGDGNSPFAGGIVIDPHGEYYRDLKAFNTPNDTRIVHLTMSPDSNDENEKSLHIPLNILTPNDLCEVKDFASETQIPFMWACRKLHRNLNLNGPSGSEDEVSAQKEILEKAKNWVDMILNCDTQLLMRALPDYGQQSKGDAIIGAVKRRVRGIIREDSDIWLEEYYPIIEEVIEGTTRGVWYVLDVSRISDDTSKLLSSLFSYKLFNAYKKASLEDRKAWESFKPAGVLIEEAHNYLSPEESSKGNTIAKIAKEGRKFKVFTIVVEQDPSGIDQRVLKQIHNKITLQLIPKDARALTETTPYMDELVDKIPYYEQGEGVFVSTGSFNFALPVKFPHISEWLDSNSELCKKCNNKKTFSSDKICAACQGKKKRDDIRSMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG44</accession>
    <name>A0A832XG44_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">P-loop NTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010224">
        <property type="entry name" value="MinD_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025501">
        <property type="entry name" value="MinD_FleN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003092">
        <property type="entry name" value="MinD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01969">
        <property type="entry name" value="minD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="256" mass="27419" checksum="A117CDB71884D679" modified="2021-09-29" version="1">MTRIMAIAAGKGGVGKTTTTVNLGSALAKLGKNVIIVDTNLTTPNVGLHLGMHGKMTTLNDVLEGNANIIDAIHIHESGMRVIPAGLHMRYLKTTNPNRIWDTVLDLFGSADFVLLDTPAGLEEGAKAVLNAGEEVLIVTNPEIPALTDALKTVRMAYESGAYVVGAVINKYRKDPKALRKEEIEAMLDLPVIGIIPHDDEVRKSIQAKNPVVLRKPKSPGAMAYKRLASELAGVEYTVPAEGLPVVNALKRMFGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHB3</accession>
    <name>A0A832XHB3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein translocase SEC61 complex subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023391">
        <property type="entry name" value="Prot_translocase_SecE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008158">
        <property type="entry name" value="Translocase_Sec61-g"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103456">
        <property type="entry name" value="SSF103456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00327">
        <property type="entry name" value="secE_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="54" mass="6211" checksum="128343526252F31C" modified="2021-09-29" version="1">MGKLNDKFQQYVRIMRIAKKPGSHEFKTILKVTGLGIFLIGFLGFIIKLLARLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHF2</accession>
    <name>A0A832XHF2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chromosomal protein MC1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_00940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Protects DNA against thermal denaturation and modulates transcription.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042262">
        <property type="term" value="P:DNA protection"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008674">
        <property type="entry name" value="MC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036620">
        <property type="entry name" value="MC1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05854">
        <property type="entry name" value="MC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102875">
        <property type="entry name" value="SSF102875"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MC1" evidence="3">
        <location>
            <begin position="3"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="17"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="96" mass="10827" checksum="F0DA32252D712AC9" modified="2021-09-29" version="1">MAEKKYYVLRNRSGDTEHVFSGSSPRQAALKAATRGNSSIMLRERGRRNKDGTYSVHCFKGSVKVVDAPENRPSWLPARVKKPIVRKSGVERINKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHG1</accession>
    <name>A0A832XHG1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="156" mass="16961" checksum="55F54FC8C73B0137" modified="2021-09-29" version="1">MVEFKTIKSEEIQFGNNNFIEVARKEAVAEEGSNEFVAISRGYYAPDGGKRFKKSFAVPLSPEVVDFICTKVKELAGEISVADTAPAEESAAEEAPVEETEAEEAPAEAVEEVSEETTEAEEVVPEEPAAEPVEEASEEETTEAEEPAEDEEEKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHL3</accession>
    <name>A0A832XHL3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2073 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012017">
        <property type="entry name" value="UCP004977"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09846">
        <property type="entry name" value="DUF2073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="144" mass="15856" checksum="97469919471EB5FF" modified="2021-09-29" version="1">MAKARKKPLKKKKIVKRKSRSSKKSLKIDFISMSKLKGDTIEAKIDIILDKVKIGHVVILDEALSPDEEAHLVTETMEGINEEFSGIEFCSLPRQSGKARMLLSRVAKLLGIEMTSPGVTLVGPSTIISDIKRDLGAFHVSAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHP3</accession>
    <name>A0A832XHP3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl2</name>
        <name evidence="7" type="ORF">H1011_02680</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_A">
        <property type="entry name" value="Ribosomal_L2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023672">
        <property type="entry name" value="Ribosomal_L2_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="90"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="190"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="239" mass="25341" checksum="85AA004E8A83B25A" modified="2021-09-29" version="1">MGKRIRAQRIGVSPRRRSPGHRFKGAIKHASLQSFAEGTSKGEVIDFLHDPGRTAPVARVKFEDGSIESLIAPNSLSIGDEVSKGPSAKTSLGNSVFLSKIPEGTLVYNVEANPGDGGKFARASGTFIKIVSHDPTGTVVQMKSGAFKTLNAKCRANVGVVAGGGRLEKPFVKGGTKRKVMRARGKLHPRVSGVHMNPTDHPFGGGNHPHIGKPKTVSRHAPPGRKVGSISPKRTGKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHT8</accession>
    <name>A0A832XHT8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="85" mass="9173" checksum="819D2667D0DEEC73" modified="2021-09-29" version="1">MAEAKKTQVGTVIHYYGNASVAVVDLTKVLKVGDKISIVGENTDVQQTVESMQLEHTQIEKAKKGDSVGLKVDGRVGKNSKVFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIQ5</accession>
    <name>A0A832XIQ5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="186" mass="20620" checksum="CC32B34535C2F983" modified="2021-09-29" version="1">MAEDIQEISVVPKGESLGSEDVKKELEAMEEILGKIVHPIAVRHRDIASNMKDAIHSLKKELKHPEMSSAEAHEGEDENLFIVSLSLVSIVRSLITYYTERKKGASEDEKAHIGKILSSLNFATSIKRGVTTWTGEGPLMSAARNIRQLAEIESKKTGKKTWRLRGHEVRIAGKEAHETGQELAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIT0</accession>
    <name>A0A832XIT0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flavin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="2">
        <location>
            <begin position="10"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="186" mass="20991" checksum="5EA8CCC03061CE11" modified="2021-09-29" version="1">MDLKWDDERTRKFVTNVGLVTSNGPHGNNIMAAEWTHHISYAPSLLAVCIGPNKATLDNIRETKEFGVHLAAFDQSVFSSIAGGNTGKEVNKIAILKDLGLRFYKASKVDLLMLKDAVMQAECKLMQEIELGDHTMMVGEVVEIRSTKKEPLIYRGGKYWNFGDQIEKPRQELLDKIKELVEKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIT5</accession>
    <name>A0A832XIT5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpl6</name>
        <name evidence="5" type="ORF">H1011_02610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_A">
        <property type="entry name" value="Ribosomal_L6_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019907">
        <property type="entry name" value="Ribosomal_L6P_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03653">
        <property type="entry name" value="uL6_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="4">
        <location>
            <begin position="11"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="4">
        <location>
            <begin position="103"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="176" mass="19466" checksum="2C3AD159C8FEF1BA" modified="2021-09-29" version="1">MAENLTKIIEVPPEVTADVSGFVLKASGEKGSIEKELIYPGVSMKKEGSSIVFESKNTRKEFKAIIGTYSAHLKNMIKGVSEGFEYTLKVVFTHFPITLKEEKGVVEIHNFYGEKVPRKAKILEGVDVDLQKDQVIVSGIDKESVGQTASNIQNATKVKGRDTRIFQDGIYVVSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIV2</accession>
    <name>A0A832XIV2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stage II sporulation protein M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002798">
        <property type="entry name" value="SpoIIM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01944">
        <property type="entry name" value="SpoIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="261" mass="28863" checksum="84A5657A39889DAF" modified="2021-09-29" version="1">MVIENIIRPEWVERNPLYGFILGACISTIGIFLGPMIFPNDASLAGVLLTTIAGLPFLHKIMRIEQQVGSYMAGTESFIKRNAHLMLIYFMFFMGMTASYLIWAIVLPGWMISLVFSKQFAAFSGGTYTTALGKFIMGTSVFMAIFMNNMRVLFTLMLLSVIYGAGSMIILVWNASVLGVFITSLFSRAGLLVSSIPHIILEFTGFFLAAVAGGLLSIAFLRVDWHSEQFWQTITDSLYLIVFGIAFIFAGAFVESMLILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIW0</accession>
    <name>A0A832XIW0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="7">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="7">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pheS</name>
        <name evidence="9" type="ORF">H1011_03080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="7"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00282">
        <property type="entry name" value="Phe_tRNA_synth_alpha2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022917">
        <property type="entry name" value="Phe_tRNA_ligase_alpha_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="235"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="485" mass="55187" checksum="E2EFAD468EA521AA" modified="2021-09-29" version="1">MDLHPIESKVIKGLKTLGGKGSASEVAEAGGIEKIQEERFGYSLSEKGFVKLNKNVSDSLKLTKLGEKYLKKGLPERQILDALKTGLKSSKELAEELNIDENAISACIGIFKKNAWADVRKGDKGLVFEITDLGEKLLGRGEFGSLANLDSFGPEQANELKKRGIVENDDTTTYLLELLKEPKTSRGRAIENITPEILKNKSWKGRKIRGYDINAQTQPYFGGTLHPHTLATEKIRRTFLELGFEEMGGNYVESTFWNFDALFQPQDHPSRDLADTFYLKNPEKSRLPEKKYVDAVKRAHEEGTQGSTGWQYDWKRSLAEKPVLRTHTTAVSARWLTKIKPPAKVFCIGRVFRNETVDYKHLPEFTQIDGIVIDENASFRDLLGYLKEFFTRLGFDKIRFRPAYFPYTEMSTEIEVYLKDKKEWIELGGSGLFRPEVTEPLGINVPVLAWGLSIERPLMMSLGLKDIRSFFYKNDLKWLREVPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XKZ0</accession>
    <name>A0A832XKZ0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TrmB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="8"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="130" mass="15767" checksum="6F076232313ED46D" modified="2021-09-29" version="1">MEENIRYLKRLGLTEYQSKAMVVLLNKRKTTAKDISDLSGIPLTKVYQVLKDLEEKKLLYSEEDKPRMYRTLPAYKIMNRLLAEKRRHLDRLLKERGRRLESIRKLDFEEYIRIYEEKIHPCVGVEQYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL00</accession>
    <name>A0A832XL00_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl11</name>
        <name evidence="10" type="ORF">H1011_00250</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="9">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="8">
        <location>
            <begin position="69"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="227"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="162"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="230"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="286" mass="30263" checksum="7425950D96720D58" modified="2021-09-29" version="1">MANQIKTLVTGGQASAGPPLGPALGPLGVPVNQVVEKINEATKEFAGMRVPVIVTVDPKTRAFEIEVGSPPVSALIKKELNLERGSGSPTTEKVADMVIEQAIKIAMMKENSLMAGSRKAGVKTIIGTCQAMGILVQGKTAPETLKDIDAGMYDEKIESGKTELSEAELQKIEDDKIRLAEEAEKMREENEAKAKELIGALKGKPDDEVRAALKEAGIPNNLILELLPKEVEPAEGEEGAEGAKEEGAEGAKEEGAEGAKEEGGKDKKEGGKDKKEGGKDKKGRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL12</accession>
    <name>A0A832XL12_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Diphthine--ammonia ligase</fullName>
            <ecNumber evidence="2">6.3.1.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.14" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01994">
        <property type="entry name" value="Alpha_ANH_like_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002761">
        <property type="entry name" value="Diphthami_syn_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030662">
        <property type="entry name" value="DPH6/MJ0570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022427">
        <property type="entry name" value="MJ0570_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196">
        <property type="entry name" value="PTHR12196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01902">
        <property type="entry name" value="Diphthami_syn_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039123">
        <property type="entry name" value="Diphthamide_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03679">
        <property type="entry name" value="arCOG00187"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00290">
        <property type="entry name" value="MJ0570_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Diphthami_syn_2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="227" mass="24796" checksum="15D2EC3A258BA7F9" modified="2021-09-29" version="1">MRLAALFSGGKDSTVSLYRAMQDGHEITHLVTAVAANPDSYLFHTSAINMAELAAEAMGIPLVKVIIESTFDTGEAEELKEALSKLDIDGITLGGVSSNYQGNIFTGIASKLGLEVVAPFWEKPHEELIEYALDSGFKIIFVSISADGLDQSWLGRELNRETYEELKKIRETHRIDIGGEGGEYCTLVLDGPIFKKSIKIEDSEISWKGMAGKLIINKAILSEKATQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL38</accession>
    <name>A0A832XL38_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type 1 glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01741">
        <property type="entry name" value="GATase1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044992">
        <property type="entry name" value="ChyE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42695">
        <property type="entry name" value="PTHR42695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="31"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="222" mass="25451" checksum="39490FB80D21B6CB" modified="2021-09-29" version="1">MKILIYDCHKSRVQESEKIKKALLRGHPDLEIDIAEVRKFQFPDTENYDAFIVSGADGHSEKHAWPRLIKEQIAKIIGIGKPVLGVCFGSQILAELYGFEIITLKKPEIGWVQVKLTDLGKEDQLFKELPTSLPIYQYHIRAVKGGGKVLAESRNCIQAVKYSDTIYGIQFHAEESPESGKEYLKTDRKCENYEEASTLAPEEYIEWKIYRNFIDIITKTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL68</accession>
    <name>A0A832XL68_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dihydroorotate dehydrogenase electron transfer subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_01575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="2">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019480">
        <property type="entry name" value="Dihydroorotate_DH_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10418">
        <property type="entry name" value="DHODB_Fe-S_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1 2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="3">
        <location>
            <begin position="4"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="263" mass="29248" checksum="F5B8E64B370D5A6C" modified="2021-09-29" version="1">MEFDVEKTYKVSEIRQETDKVKTFFFDFPKKAKPGQFIMLWIPGKEEVPMSVSYSDGKRLAISAFAVGETTETLHTLQVGDLVGIRGPLGNPWTLEGRKLAFVAGGYGSAPLAFFAEELGEDSEISAFLGARTKDLLLFEERLKKSCKEVICTTDDGSYGEKGLVTEPLEKLLQKKEFDTVYVCGPEGLEKAVFDLCEKYDVEMQASLERIFKCGLGMCGACVAGKYRICTDGPVLNREQLRGVEDFGKFSRDKSGRKKNYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL83</accession>
    <name>A0A832XL83_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-directed RNA polymerase subunit A</fullName>
            <ecNumber evidence="3">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="3"/>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb1_5" evidence="2">
        <location>
            <begin position="37"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="379" mass="41816" checksum="7D2706984F653D04" modified="2021-09-29" version="1">MSESSKSSEEAVSLLPPKLRKEAEEFASKIKSRKQSEDFLNLVTSTYLKAKVEPGEGVGVVAAQSLGEPGTQMMMRTKHYAGTAMDVTRGLPRLIEIFDARRTPKTPMMEIYLDKANNTIENAESIAHRLKETRIKNIMTEMSTDFAKYSVTVTLDRNELKKRNITPKKLENTLIEIYGNRVSVEGGNKAVIKTEKKVASLLQKLKEDLRETHLSGIGGISYVVVQKKDRDFILYTSGTNLKDILLVPGVDASRTKSNDILEVEKVFGIEAARNMLVEETILTLDDAGLSVDNRHITLVSDTMCADGRVKAVGRHGISGDKASILARASFEETVKHLLRAAAYNESDPLNGVVENIIVGQVINLGTGVPELIMKKVDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLB1</accession>
    <name>A0A832XLB1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="73" mass="8427" checksum="1CB9D408F99EEFC5" modified="2021-09-29" version="1">MSDEFSEKKPIVDKEKCIGCCLCPTVNFEDPDFKMVQTEQGEKAEVIKKKKYNTKMIEESIEYCPVDAISQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLC0</accession>
    <name>A0A832XLC0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps8</name>
        <name evidence="6" type="ORF">H1011_02615</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_A">
        <property type="entry name" value="Ribosomal_S8_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="129" mass="14360" checksum="C68E6D3BE6B7FDE4" modified="2021-09-29" version="1">MMHDPLSDAMVNIQNYSSNGKSECTILVASNMLKSLLEVFKSKGYIADFKEVENRKGGSFQVSLLGKISKCGVIKPRFPVQVSDIEKYERRYLPAKGVGHIILSTSQGILTHEEAYEKKIGGVLLAYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLC8</accession>
    <name>A0A832XLC8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="69" mass="8033" checksum="BB467A8F065E7142" modified="2021-09-29" version="1">MALTLEAILYYLFVVDSSIYFVLSHTTGKFHKRKDHHIVKWVPLNKLFALIYIGHVVWVGISLHRLGIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLD9</accession>
    <name>A0A832XLD9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="100" mass="11129" checksum="082511D4984A853F" modified="2021-09-29" version="1">MPLLLLAVIVISGCISYSGDSENASPEITLALEEIDISVQGEACWKTEEVLEVNYLGKYLVAEEEITLYLQGKPVNKKYIEILDEEEGLERILLKKVATV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLG1</accession>
    <name>A0A832XLG1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="67" mass="7399" checksum="41BC1CB57C846AC7" modified="2021-09-29" version="1">MAKGIISCPKCGHAQDMEIPEAICQFSYLCFGCKETILSETKCCVFCDYGDKPCHSGKKEAEVMIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLG9</accession>
    <name>A0A832XLG9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA-directed RNA polymerase subunit Rpo3</fullName>
            <ecNumber evidence="4">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">DNA-directed RNA polymerase subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpo3</name>
        <name evidence="4" type="synonym">rpoD</name>
        <name evidence="6" type="ORF">H1011_03600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the RNA polymerase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00320">
        <property type="entry name" value="RNApol_arch_Rpo3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001514">
        <property type="entry name" value="DNA-dir_RNA_pol_30-40kDasu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022842">
        <property type="entry name" value="RNAP_Rpo3/Rpb3/RPAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00446">
        <property type="entry name" value="RNA_POL_D_30KD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4 6" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOLD" evidence="5">
        <location>
            <begin position="28"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="203" mass="22274" checksum="E04B93E909E308E4" modified="2021-09-29" version="1">MAISGRRVAGEGGEYKMKISNVKKEEDVLEFTLEESTTAFANAIRRIIMSEIPVLAIRDVTFIDNGSALYDEVLSHRLGLIPLKTPVRMRADTEVKYTLVKKGPCTVYSGDMKSSDSKLAPSDEKIPIVKLLEGQNIKLEATAILGTGKDHAKWQAAIASYSIDKDKFNFRVEKTGAMDPERAVVSAAKVLSGKAKELEKLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UL75</accession>
    <name>A0A832UL75_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">H1011_00025</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022495">
        <property type="entry name" value="Bud32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209">
        <property type="entry name" value="PTHR12209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03724">
        <property type="entry name" value="arch_bud32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="201" mass="22724" checksum="3C52F8B0FA47EAD5" modified="2021-09-29" version="1">MNKLLKVGAEAKLSLEDGIVVKERISKGYRIPEIDSSLRKKRTRREASLLDKARRAQLKVPAVKDLDKDNNTIYMEFIDGEMFHKVMNSPLSKKLGSELAKLHDAEIIHGDLTTSNILVKAKDIYFIDFGLGEISDSIEKKAVDIRVLKESIKASHPKDSGKHIESILEGYSSSRSFDAVLERLETLEGRGRYKKKVNKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UL98</accession>
    <name>A0A832UL98_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">tRNA (cytidine(56)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="6 10">2.1.1.206</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">tRNA ribose 2'-O-methyltransferase aTrm56</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">H1011_00200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>cytidine(56) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(56) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42968"/>
            <dbReference type="Rhea" id="RHEA-COMP:10308"/>
            <dbReference type="Rhea" id="RHEA-COMP:10309"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.206"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the aTrm56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.206" evidence="6 10"/>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002128">
        <property type="term" value="P:tRNA nucleoside ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00077">
        <property type="entry name" value="tRNA_methyltr_aTrm56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002845">
        <property type="entry name" value="tRNA_mtfrase_aTrm56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42197">
        <property type="entry name" value="PTHR42197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01994">
        <property type="entry name" value="Trm56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016123">
        <property type="entry name" value="UCP016123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 11" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 10" id="KW-0819">tRNA processing</keyword>
    <feature type="binding site" evidence="10">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="170" mass="18927" checksum="8DBBED3CEFEC2209" modified="2021-09-29" version="1">MEAEVLRLGHRAHRDARVSTHIGLVARALGASKLHYSGQKDDSLEKSINDISDRWGGDFEADYVKNWKKFAKEFDGIKVHLTMYGDLVQNKIEKMVGKKVLIIIGGQKVPGEVYDIADYNIAVTGQPHSEIAALAVFLDRHSRGKALETEFPDADISVKPSERGKDIVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULH0</accession>
    <name>A0A832ULH0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000005">
        <property type="protein sequence ID" value="HIJ99353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="59"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="146" mass="16952" checksum="A57C7D4FC09BA529" modified="2021-09-29" version="1">MATTQQAQKQADVSDFGWRLNSLITKVRINEQNVINERKHAQLLNKNLIDFKGEIRGKMESITQQNRELKLSMDRVKEQIKTLTKKLNDLPSKAELNELRRIQESATLYGRDMSKDEADEILDKVLSQIEHRESGEENGNTKEKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULI2</accession>
    <name>A0A832ULI2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prepilin peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="2">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="288" mass="31891" checksum="1D6605D253974CC3" modified="2021-09-29" version="1">MFGYIALIVLLSGSLIGSWTDIKIREVSNWLTFGLIFSMLAIRLGQGIYLGQYVYLLEAATAGFLFLTLGVILFYSGQWGGADWKLLTAYGIGFGSLWGEFSPLFEPIWPFYLTLLMNIMIVSVLYTLPLALLYALRNKRVLAKCRKEVGNKEKLMMLAGFGVSATAVFYTGESVLWVFSLLAPLYALSKFLRPIENTYLTKLKKINELVEFDIPVKDVKVSGKLIISSEGPNGMTLANLKQLKKLSKSKKIPGTMLVKWGFPLAPAFPIGLVLSLIVGDFVIAFASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULJ1</accession>
    <name>A0A832ULJ1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ribonuclease HII</fullName>
            <shortName evidence="10">RNase HII</shortName>
            <ecNumber evidence="10">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rnhB</name>
        <name evidence="13" type="ORF">H1011_00985</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10 11">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 10 11">Belongs to the RNase HII family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="10"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_A">
        <property type="entry name" value="RNase_HII_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004649">
        <property type="entry name" value="RNase_H2_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020787">
        <property type="entry name" value="RNase_HII_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023160">
        <property type="entry name" value="RNase_HII_hlx-loop-hlx_cap_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00729">
        <property type="entry name" value="TIGR00729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10 11" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 10 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="12">
        <location>
            <begin position="5"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="HIJ99383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="219" mass="24236" checksum="90F30573554C9A24" modified="2021-09-29" version="1">MTRILGVDEAGRGAVIGPLIVAGALIDEKDEGKLIEIGVKDSKLLTHKKRGELHQQLGQILAESRLEVISAAEIDSSKEEGINLNELEAIKSSEIINNLKPDTAFIDAVDTTPLKYKGRLVNHLSVDPKLVIEHKADSTYPIVSAASILAKEAREDAISELKKKVGDFGSGYPSDPLTKEFLTRWLNEHNSFPTWVRHSWKTISTKLGNKTQKNLEEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULQ6</accession>
    <name>A0A832ULQ6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alanine--glyoxylate aminotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="2">
        <location>
            <begin position="20"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="350" mass="38555" checksum="97139C86D5A0220D" modified="2021-09-29" version="1">MVPLLMTPGPTEVPERIRTALAHPIVHHRTPEFTEILDDCGSRLKKVFKTDNTVYTMSGSGTTAMCAALENTVSKGDKVLSIVFGKFSERFRDIALSIGADLETLQFDWGQAPDIEKIEEALDDDVKAVTMVHNETSTGVRADVEAVGKLVKDTNALFICDTISSMAGDNVETDNWNIDLCIAGSQKCFSMPPGIGFLSVSDKAWPVIESKKQNYLTDLNKYRSKYPQTPFTSPISLIFGLQEALSIIEEEGLDKRVQRHRENAEFTRTAVKELGLELYPASEDICSATLTSIRSDRAEEILSALKEKGILVAGAQAPENGKMFRIGHMGSIGRPEIERTLEALKEVLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UM30</accession>
    <name>A0A832UM30_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L31e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl31e</name>
        <name evidence="7" type="ORF">H1011_02725</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ribosomal protein L31e family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00410">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_L31e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_L31e_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="PTHR10956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="SSF54575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="135" mass="15610" checksum="341C35DFDAC343FB" modified="2021-09-29" version="1">MAETTKKDTKTAKKAEKAEKPEKLEEAETAKAEEVPKKQKKSKEEEPVEEFKAVLTRVYTIPLRKQYNTTSKAKDASKRVRSYIEQHIKPTAIYIDPELNEKIWKRGYKKSPASIRVSVEKNKEGFARVSLRKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UM48</accession>
    <name>A0A832UM48_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_02880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="40"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="207" mass="22773" checksum="86CACC8BD247928D" modified="2021-09-29" version="1">MERKYISIWIVAITSGAFLVQMNAPITDSFALISSQAAIHPWTLITHMFMHGGATHLLYNMFALALFGTILEVTIGWRKFLVIYFAGGLVAGFAALPFYSASIGASGAVFAVMGALAVLKPKMIVYVGWIPMPMAIAAAVWAFGDLVGMFAPSGIANAAHLGGLAFGLGYAFFLLKEFHEWGNKNKRHNTEEDWEDSYFDEAEMRWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UME4</accession>
    <name>A0A832UME4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="7">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">metG</name>
        <name evidence="10" type="ORF">H1011_03640</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="7"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="B3_4" evidence="9">
        <location>
            <begin position="598"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="325"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="759" mass="87060" checksum="F210D4A31874A9D2" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UP66</accession>
    <name>A0A832UP66_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Site-2 protease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_00130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001193">
        <property type="entry name" value="MBTPS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13325">
        <property type="entry name" value="PTHR13325"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01000">
        <property type="entry name" value="SREBPS2PTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="6">
        <location>
            <begin position="110"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="396" mass="43218" checksum="5D4A024D5C9254CF" modified="2021-09-29" version="1">MGAVFVWTIVIGLILVGQLVLSKHKGVSIYGPLAVYNTKRGVKLLDKISGISPRFWKVFGNLGVITGFFLMALVTYSLLINAIRIFRIPEAAPGAALAIPGITIPLWEGIIGIVILLVFHEMSHGVLARREKVKVESVGTLSLGFIPIGAFVRPNEKSIRKAKLSARMRIYAAGSFMNVTLAIILVSLLAFVVLPYMTEPVDGIKLLAVEEGSPAELAGLSEGMIIQEVEDGKIHDLVSFVNTLDRQDLSPGDEIIIKIDDSEYTVTTAERNGRAFMGITFCGAIPAGEIVKLFIASPMTIRILSPECYPSTLLPQKTMWFIIYAIMWTAILNFGVGLINLLPFRPLDGGLMFSDAVRRIIKNEKLAKQIIIVVGSLVFLLLLFNFIGPKLLGILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UP84</accession>
    <name>A0A832UP84_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MauE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_00220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030416">
        <property type="term" value="P:methylamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009908">
        <property type="entry name" value="Methylamine_util_MauE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07291">
        <property type="entry name" value="MauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="MauE" evidence="8">
        <location>
            <begin position="67"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="189" mass="21086" checksum="25E6DFE7831EF392" modified="2021-09-29" version="1">MSKKDPICGMDGTIEKHGYYFCSQNCIEKYESRPALMSQSWFKPVLYSVIAVLLIVLTAVLQMTGYMILFMGVFFVAVSLLKIADWKGFAQAFTMYDILAKKSKVYAHIYPLIELGLGISYLLTWQITIAAYVTFVIMAIGTVGVAQNLLSKNPVKCACLGTLVKIPLTKFTLFEDITMAAMALMILFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPM9</accession>
    <name>A0A832UPM9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF371 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007171">
        <property type="entry name" value="DUF371"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023131">
        <property type="entry name" value="Mth639-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40696">
        <property type="entry name" value="PTHR40696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04027">
        <property type="entry name" value="DUF371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="137" mass="15190" checksum="8C2D0B3072EA3C7A" modified="2021-09-29" version="1">MVMEIIASGHANVLGTHPTTIEITKEAELSLQGNCIIAVRADTACSDLPEEIKKEILGGGKFKVTLQAGELTEEVIGEGSPNLFFIHHTDIVLRKSEFIDDRTLLVNCDKACSDLNREFIEELKNPETKLHFTIEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPP4</accession>
    <name>A0A832UPP4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000008">
        <property type="protein sequence ID" value="HIJ99491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="196" mass="22151" checksum="C37AECB09F4B02F6" modified="2021-09-29" version="1" fragment="single">MVKSDIKAKETNLKAVQAHLRGIGNSQELFTYMHNYCEFLLSNDLSSLRRLLLSPSLFRHMVLHSADKNKIASFRQKISTEFGIEVIILPQQEPVLPEIFFVPKIQGTGAHWSQLSKDMEWFRKNVDKLLGGTEPVMTLSRASKVRNRARRFLTNYTTILDDFASVITGGHPVDEIGSKGILSMKIMGSLQELGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPQ3</accession>
    <name>A0A832UPQ3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="8">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">thrS</name>
        <name evidence="11" type="ORF">H1011_01620</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="8"/>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 8" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGS" evidence="10">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="262"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="505"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="630" mass="72794" checksum="E09BB21905A06796" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPV1</accession>
    <name>A0A832UPV1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="1">NDK</shortName>
            <shortName evidence="1">NDP kinase</shortName>
            <ecNumber evidence="1 3">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 5" type="primary">ndk</name>
        <name evidence="5" type="ORF">H1011_02115</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="1 3"/>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDP_KINASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="4">
        <location>
            <begin position="2"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="139" mass="15369" checksum="7D2CE0C19AF1E68B" modified="2021-09-29" version="1">MTERTFCMIKPDSVKRGLVGEIIKRIEAAGFTIRAAKLSNVSQEQAETLYQEHVEKDFYQGLVDFAMEGSALPMVLESEGAVQKVRDLIGATNPENAEPGTIRGDLGEEELPRNLVHASDSIESAEREIPIFFSESELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPW7</accession>
    <name>A0A832UPW7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_02265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="123" mass="13852" checksum="6693CCEC12B9BA70" modified="2021-09-29" version="1">MVKRKYAGFFLRFVAWVLDGFILAIPTGVLAYLIPAIHPVLYIWLYYAYMESSAYQATLGKMLLGIKVTDLKGKRITFLRATGRYFGKILSGLILGIGFLMIVFTEKKQGLHDIIAKCLVVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPZ2</accession>
    <name>A0A832UPZ2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="184" mass="21356" checksum="83A28243BECD7CD2" modified="2021-09-29" version="1">MPINIKQLKKCDYFKELPEESQKVLHEFIIDSQKNATQWQYPNYFFAPPHDEAETMQLWIAIMKSSCQEHNEIRKLRGKVISPFVGPVLVEFYSRYAETKKKGNPLLVLSVDSLLRLMKKKWLVITPLTNSVALFRDFDIERLKRATDVYNIISSMSNTLMKVGPGKGNARITEHAIELIEKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQE1</accession>
    <name>A0A832UQE1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="85" mass="9104" checksum="8C57275CDC4A0305" modified="2021-09-29" version="1">MNPEESETECPCAEDCTCGDCKCEKSDCGCCKKEEAPAEESTETPEEAPAEEKPAEESEEAPAEESTETPEEAPAEESEEKPADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQF6</accession>
    <name>A0A832UQF6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">tRNA (Guanine(10)-N(2))-dimethyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.213</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_03570</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.213" evidence="8"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004809">
        <property type="term" value="F:tRNA (guanine-N2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002905">
        <property type="entry name" value="Trm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042296">
        <property type="entry name" value="tRNA_met_Trm1_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10631">
        <property type="entry name" value="PTHR10631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02005">
        <property type="entry name" value="TRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00308">
        <property type="entry name" value="TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51626">
        <property type="entry name" value="SAM_MT_TRM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 7" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="355" mass="39583" checksum="CEEAA595ECD21C64" modified="2021-09-29" version="1">MGVSSTEISEGKVKILVQGGEHKPEKTVGFYNPRMEFNRDFTIATLAAVCKKGWKALDAFGASGIRGIRFCKEIDGLEVTINDISQGAISLIKKNVKRNKVLAEILKRDAAALMNERKFDFIDLDPFGSPAPFLEPAFRSIRNKGIVGITTTDMTALCGIYPKVAKRNYGGTSLRTEYCHEIGARLVIAAAVRAAARFEKGIQVLSVLNADHYLRITLRATEGAEDANKSLENIEPAYHCFDCGEHGFEKKCKCKKKLSEFGPIWSGSIFDEKFIKSGLKIVETRDFGTQKRLIKTLELMKEEAGGSVFYYDLHKRYKGNVPRIAEAIEKLNEKGIKATRTHFNPTAIRSEKFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832USZ4</accession>
    <name>A0A832USZ4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_00085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="8"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="254" mass="27869" checksum="E94F21FF038A4055" modified="2021-09-29" version="1">MNNLIGLSALARREIKRFLSISGDTLVTPLISSLLYLFIFGYSIGKLVPSFSGISYMEFIIPGIIMMSVIQSSYTNTSFSIFISKWAGNIADLLTAPLSYMEIVIAITIGGVARGLLVAAGVYLVSAFFAGFLMYSFLHTFVFLVLITIVFSLAGIVVAIVSDDFEHLTVFNAFILTPLVFMGGVFHPVSILPPLFQKITMFNPLFYMVSGFRYGLTGVAETSVLSSFLVLVAFIVVLFATVVTMFKRGYKLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UT03</accession>
    <name>A0A832UT03_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">L-2-hydroxyglutarate oxidase</fullName>
            <ecNumber evidence="2">1.1.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lhgO</name>
        <name evidence="2" type="ORF">H1011_00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.3.-" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="5"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="391" mass="42835" checksum="96F56559531D2134" modified="2021-09-29" version="1">MEKKHYIIIGAGIIGSSIAREISLRGLGKVTVLEKEGKLGMHASGRNSGVVHSGINQKPGSIKAELCLKGNQLLKQFCRKHKVRVEEVGTLVISNSDEDDKILEQLMSRGKKIGVRGLKIINSEELKRREPEVVGRKALLSPSGAIVDSVGFLEAVVKDAKKHGAEFIMDAKVTGIRGNSVKTRKGIFEADHIINCAGLYSDKIAHVMGAGRGIRIVPFRGEYMEVENLDIRSMVYQAPDLNFPFLKVHLTKTVDGKVLAGPTATLALGREAYRKGINPVEFIGMASSVNFLRLLFGKSFRKLVAENVKVTVSKKAFLKEIRRISPSVKRGDLKKHPPGIRAQPVNRKGELVNDMLVEFTDDVTHILNAVSPGLTASLSFAEYVVDRIEGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTD1</accession>
    <name>A0A832UTD1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="198" mass="22302" checksum="92ABA1AD838E9225" modified="2021-09-29" version="1">MPKTNKEAIKVSKRSLLVFFLAVVSIITFIFIIPSFNWASHGKYFVLPFAFLAILITRRADSWKVGIEVFYFSPFLLAYTYNLFIALAISFLAFYFVVKTKPSEGNGIVIHSVIITIIATIASVLSGHFGTNITEMQFFWSAYGTVLFAIWVDAIIVKFSAPVPLPKNIITHTMGSFSNYILISKIGYPVFLYILTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTF1</accession>
    <name>A0A832UTF1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">DNA repair and recombination protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">radA</name>
        <name evidence="10" type="ORF">H1011_01275</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the eukaryotic RecA-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01123">
        <property type="entry name" value="Rad51_DMC1_radA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00348">
        <property type="entry name" value="RadA_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="DNA_recomb/repair_Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011938">
        <property type="entry name" value="DNA_recomb/repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033925">
        <property type="entry name" value="Rad51_DMC1_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02236">
        <property type="entry name" value="recomb_radA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RECA_2" evidence="8">
        <location>
            <begin position="131"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="9">
        <location>
            <begin position="307"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="160"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00018144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR005856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="366" mass="39891" checksum="0BE579370C57F9B9" modified="2021-09-29" version="1">MAEEKIEETEEEALDEKEESSAEEAPVEEAEESEEATEEDSDEDDEIDNDAEEDAGEGSLEDLEGIGPATAKKLMDGGYSTIKSVATAAIGDITEAAEISEAKAKKVITLAKEKCNMGFESADRLLIKRQDIGKLTTGSETFDTLLAGGMETQAITECYGEWGSGKSQVAMQLAVTVQLPVDKGGLDGEALFIDTENTFRPERIVQMAKGMGLDPDEALKKIHVARAYTSDDQMLMTEKAAEMVRDSNVRIVIVDSLTSLFRSEYVGRGTLAARQQKLNRHLSTLHKLADLNNCVVYVTNQVMSKPDMFFGDPTKPIGGHILGHSATFRIYLRKSKAGKRIARLVDSPNLPDGEAVFKVTENGLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTG3</accession>
    <name>A0A832UTG3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="165" mass="18517" checksum="A0DF257D5E813C9B" modified="2021-09-29" version="1">MAKKSTAKKGKKNGKGKLTMKHRELIEDAGWFNAGIIIEVQGNNKEHVSSTLEALVERLGKEEDVKIYSTDYDEMQEFKDGFFSLMVDTRFITKDFGRLVHIALLYSPSVFEIYSDKKDVGIAIGDAQNILVDVSNLVNRLAHQVFILKGHINRLESGEKNGKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTQ4</accession>
    <name>A0A832UTQ4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="175" mass="19907" checksum="B11693D7FB2E1683" modified="2021-09-29" version="1">MNLSEVEFRQPSIEDSETCMEYINCLVDEGTHIAHLEKFTLEEEQEYLTYIQKMCEADRGVTLAAMYKGKIVGLCGIDREYMKKSAVDHIGLMHIGVSSNWRGSGLAKLLFENTLEASKSLGIEAVTLSCDSNNERALKFYEKLGFSRVASLKNYVKRDDNYSDLILLEMWLPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTX7</accession>
    <name>A0A832UTX7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="2">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="2">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">truB</name>
        <name evidence="5" type="ORF">H1011_02550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01081">
        <property type="entry name" value="TruB_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026326">
        <property type="entry name" value="TruB_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="PTHR23127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DKCLD" evidence="4">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="3">
        <location>
            <begin position="244"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="326" mass="35889" checksum="44E29F09FEEB31C0" modified="2021-09-29" version="1">MNPGKLPFEKERELLIRREEETNPDFGCLPTERTIEELLKGCIINIDKPAGPTSARITDFVKEIIGTKKCGHSGTLDPGVTGVFPVGVGTGTKALHSLLIAGKEYLTLMRLHEEISERKLKKVLKRFTTKLYQTPPIKSNVNRVLRIREVYYTKLIESEVKDALFTVGCEAGTYIRRLCYDIGEVTGSGAHMQQLRRTRVANFNEDTLFTLQQLKDAFVFWKEGDESELRKALLPMESALSHLPKVTLSDSAIPSVTTGAQLAVPGILSVESGISPGELVAVLSQKGEGVLYGSALVSSEDMVSLPKGLAIKTERVLMNPSIYSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UUB9</accession>
    <name>A0A832UUB9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Vitamin B12-dependent ribonucleotide reductase</fullName>
            <ecNumber evidence="9">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">H1011_03535</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the ribonucleoside diphosphate reductase class-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="9"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02888">
        <property type="entry name" value="RNR_II_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013344">
        <property type="entry name" value="RNR_NrdJ/NrdZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02504">
        <property type="entry name" value="NrdJ_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="8 9" id="KW-0170">Cobalt</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuc_red_lgN" evidence="10">
        <location>
            <begin position="49"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="RIBORED_LARGE" evidence="11">
        <location>
            <begin position="130"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="824" mass="92394" checksum="7257BAE1AFA24476" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UXX6</accession>
    <name>A0A832UXX6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Ribosome biogenesis protein Nop10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nop10</name>
        <name evidence="9" type="ORF">H1011_00555</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NOP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00803">
        <property type="entry name" value="Nop10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007264">
        <property type="entry name" value="H/ACA_rnp_Nop10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036756">
        <property type="entry name" value="H/ACA_rnp_Nop10_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023532">
        <property type="entry name" value="Nop10_arc-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04135">
        <property type="entry name" value="Nop10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144210">
        <property type="entry name" value="SSF144210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 7" id="KW-0698">rRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="26"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="57" mass="6628" checksum="5CFFC10781F0D441" modified="2021-09-29" version="1">MMAKILRCTKCRQYTIKTICPNCKTSTASPEPAKYDPKDKYGKYRRQARTDGNLRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UY50</accession>
    <name>A0A832UY50_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="258" mass="28778" checksum="251CBBC18627A29F" modified="2021-09-29" version="1">MYEVFPELRPAFDRIGEGDLSGAAEELEKAEEELAKTILGRKFSKGMGKTEEFVENIRDLLKRMKITLKVQSAAAVIVEREGGDADLRKQNQELIRMSVQETREIMSLTKELDEMDKKDIFEDVLEEYQRIMKTEDSELISSGEFLEKLNVLLEGVGMSRKERTAIMNVLKSGKGNLKPGTFGWSSFTIVLGSSISASGILMMDFLSNFEGGVAGQSIRASFGATLMGLLLVQGGIFQIINEVGQGYDIKTLKKIFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYG6</accession>
    <name>A0A832UYG6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="122" mass="13634" checksum="54F43C967AEBD928" modified="2021-09-29" version="1">MKRQVWKVFQFTGWFVVLLAITLGLLYASILVGEQIYGSALLVVVGIILVIVGEHFISIKYAKRYLLVWQAGSIAGAFSITIGVIWLVIQFLQAYQSWYSILILLALGIGLIVVGENFKLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYM8</accession>
    <name>A0A832UYM8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl18</name>
        <name evidence="6" type="ORF">H1011_02595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_A">
        <property type="entry name" value="Ribosomal_L18_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005485">
        <property type="entry name" value="Rbsml_L5_euk/L18_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23410">
        <property type="entry name" value="PTHR23410"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17144">
        <property type="entry name" value="Ribosomal_L5e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="194" mass="21432" checksum="A15ADDD5E926A386" modified="2021-09-29" version="1">MKRRKIAGFRRRKSNQTDYRTRLSLLRSGKPRLVVRKSLRNIQVQLVNYTDSGDTILASASSTELNGLGWNYGCSNLPAAYLTGLLCGTRSKALKVKNAVLDIGLYRPIGGSKLYAAAKGASDTGLGVPYGDSEKLSEERLSGGHIAAYAEKLEKDDKKKYESQFSEYISSKTNPKDIQTQFEATKKKIMEGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYN6</accession>
    <name>A0A832UYN6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplV</name>
        <name evidence="7" type="ORF">H1011_02670</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005721">
        <property type="entry name" value="Ribosomal_L22/L17_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593">
        <property type="entry name" value="PTHR11593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01038">
        <property type="entry name" value="uL22_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="225" mass="25436" checksum="56A8C3317DD7D3DB" modified="2021-09-29" version="1">MAKLGYTYQGGQEGIVKALVKSERISPKEAYEVANAIRSMSLPRAETFLSNVMEKKEVVPYRRYNRGVAHRKKIGPGRYPLNTSKGFMKALKLLRANAVYKGMEADSLELFHVATHRGEITPGRYKGGAHNHPTVHIELVAKESVSIQKKEEEKPEEKKVELKTEKKSEEKKAKTEKKSKVKLSEEKSEEKSEKTTDDIISEAEDVMDAEPRTSDVSEKDDKESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYQ4</accession>
    <name>A0A832UYQ4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2238 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014509">
        <property type="entry name" value="UCP020606"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09997">
        <property type="entry name" value="DUF2238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="194" mass="21674" checksum="9936A407408BE877" modified="2021-09-29" version="1">MIIKARNLKVAIATAAYMLFFTVFYIIGENYEFLLHVLVLLSFASLILYSDRKVNYPVWMLWALSLWGFLHMTGGAVYIGETRLYELILVPLSQALNLFRYDQALHAYGFGVITLVFHYIIGRPKITPAIGIVVVMAGTGAGALYEIIEFLVSLVVLQHGIGGYINNSMDLIFNFIGALLALALIKWKGFDTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYW1</accession>
    <name>A0A832UYW1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026363">
        <property type="entry name" value="CxxC-x17-CxxC_dom"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04272">
        <property type="entry name" value="cxxc_cxxc_Mbark"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="47" mass="5684" checksum="53C60EE0A9138334" modified="2021-09-29" version="1">MAEFERPQREMHKATCAECKNECEVPFKPAEDRPVYCRDCFAKRRNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZ97</accession>
    <name>A0A832UZ97_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SMC-Scp complex subunit ScpB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_01290</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="217"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="245" mass="28299" checksum="318E59BEBBAF5E29" modified="2021-09-29" version="1">MKKTLEAALFISGRRMDIKELADLVEANESDVRPLLAELVLEYGARDSPLEIIHDQEEYKMDIDSAYLHQVKAFAPQMDMSRALVKVLSFIAFKQPVKQSVVVQRFGNRVYDYVKDLLGRGLIKTEPYERTRMLSTTYKLVEYLGEGDASDMKEKIDAAKTKFGEMKSRKEEKTKKKPLGISLSEIRARKDLSANEWENLLLQEKLQETVPILDKFEKSHNESDEDDEDDDLEFLGFKKRTPRAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZC9</accession>
    <name>A0A832UZC9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000008">
        <property type="protein sequence ID" value="HIJ99487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="154" mass="17018" checksum="FC0E580FC3CEFB57" modified="2021-09-29" version="1" fragment="single">MSITMMSIFAALPGNSIAMETLWLFAFVMMLFVSELLFFYVPGFSISNLILTVIAMSFGFGPTFVIGLLSILPAHFILRKDMTMMIVSFFTLVPMVTLASFYGAYIVNLLGWPMLGFVVSVVKWGSSIVIGVLMGRAMPKKILNIMLEPLISIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZK8</accession>
    <name>A0A832UZK8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="334" mass="37530" checksum="EEF8A8CD56B67587" modified="2021-09-29" version="1">MKKVPRVAVILPAYREDPALFEDALRAVSAQTYRSFVFYIILDSACSEEVRNTAQKFAKSRKNVKVIQDKKRGSAAHRNLGTRKAGSVDYFAFIDSDCIAKKDWLENLVSEMDVQPPSIGCVGGLNLSKERSLMPRAIARAESSFMGGGSISGQTSTRRKKRFVNSLPNCNALYRRECWSENQQDESFIKGQDAEFNLRLSEQGWKFLQIPSAVVYHKRDDSLSSYSKRMREYGSAVVDIIRKQGLQGLRRFWYSAGVSTFYVLLFALLVYSSLSPPVFGIFLNLALAYLALLSFSALLTVRWGSFLPCLLAVPVLVIQHASYSIGFVRRLLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZQ7</accession>
    <name>A0A832UZQ7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster assembly scaffold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="1"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="122" mass="13407" checksum="49C550F086922A6C" modified="2021-09-29" version="1">MEHYKNPRNYGRLENADITFTGENPLCGDKLVYTLKIDNKILTDIMFEGKGCAISLAASSMLTEKIKNLAVEEIKALERSDILDMLKISIGPVRTKCAILGLVTVKCALDSSKAEGSIEVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZV0</accession>
    <name>A0A832UZV0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AMP phosphorylase</fullName>
            <shortName evidence="3">AMPpase</shortName>
            <ecNumber evidence="3">2.4.2.57</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nucleoside monophosphate phosphorylase</fullName>
            <shortName evidence="3">NMP phosphorylase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_01515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>AMP + phosphate = adenine + alpha-D-ribose 1,5-bisphosphate</text>
            <dbReference type="Rhea" id="RHEA:36975"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:68688"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.57"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>CMP + phosphate = alpha-D-ribose 1,5-bisphosphate + cytosine</text>
            <dbReference type="Rhea" id="RHEA:36987"/>
            <dbReference type="ChEBI" id="CHEBI:16040"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:68688"/>
            <dbReference type="EC" id="2.4.2.57"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + UMP = alpha-D-ribose 1,5-bisphosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:36991"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:68688"/>
            <dbReference type="EC" id="2.4.2.57"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.57" evidence="3"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016763">
        <property type="term" value="F:pentosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006196">
        <property type="term" value="P:AMP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046125">
        <property type="term" value="P:pyrimidine deoxyribonucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02132">
        <property type="entry name" value="AMP_phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017713">
        <property type="entry name" value="AMP_phosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036566">
        <property type="entry name" value="PYNP-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013102">
        <property type="entry name" value="PYNP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013466">
        <property type="entry name" value="Thymidine/AMP_Pase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000053">
        <property type="entry name" value="Thymidine/pyrmidine_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10515">
        <property type="entry name" value="PTHR10515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07831">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000478">
        <property type="entry name" value="TP_PyNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00941">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54680">
        <property type="entry name" value="SSF54680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03327">
        <property type="entry name" value="AMP_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02645">
        <property type="entry name" value="ARCH_P_rylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PYNP_C" evidence="4">
        <location>
            <begin position="424"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="193"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="508" mass="53747" checksum="94FD802DF93B5B76" modified="2021-09-29" version="1">MLKVKTIDIDFGAVEVVLNHNDALEFGLNPHDRIRVKGKCGSVVAIVNTSESLIGEGEIGIFTEIAKKICVRNGHKIDYERVGKPESLGAIKKKLDGGKLSQEEIASIVGDIVSKRITLVEMSAFVAGLQAVGMDLDEAEHLTKEMVAAGKTINFEAETFDKHSLGGVPGDKTTLIVVPIVAAAGLLIPKTSSRSITSPAGTADRMEVFAPVEHDINAIKKIVNKTNACIVWGGAVDLSPADDALIKVEHPLSLDPRPLLLASIMSKKKSVGSNFVVIDMPTGEGAKIKDKKEARDLARDLIEIGRRLDMTVECAVTYGAQPIGDSMGPALEAREALNTLEGNGTPSVIEKATAIAGIILEAGGVAGKGKGAEKALEILENGEALKKFREIIKAQGGNPNVTVEDIEKIIGKKKKVIISGRSGYVTKINNKAIGQVAKTAGAPHDKGAGVLLHAKGGTRVKKGGALYTIYAEQGFKLKEAEALALKTKPVLVEGMLLEDIPPTFLGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZZ2</accession>
    <name>A0A832UZZ2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed RNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_01900</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_1" evidence="8">
        <location>
            <begin position="15"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="7">
        <location>
            <begin position="193"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_3" evidence="9">
        <location>
            <begin position="404"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="490" mass="55187" checksum="3F9548E0BB712D81" modified="2021-09-29" version="1">MDRRSLVNKFFEENGLVEHHISSYNAFIDNGLQSVIDEIGVINPEIEGFEVRLEGIRVGKPCIKEATGAVRQVLPNETRLRDLTYASPLILELTPIQNEVEQPKMEVPIGSLPTMLRSKICNLYGMDREELIGANEDPIDPGGYFVVNGTERVLILVEDLAPNLMNVSHVKLGPTTETARVFSEGGWYRRRNSVSRKKDGGLIVEMPPFSKPVPFVAVLKALGMEKDSDIVREVASTPSLASELYVSFEDSEEAKNRNEALDLLGKKVAFGQEQEARMERAEKVLDTFLLPHIGTTPEARIYKAVYLCRMANRVIRLHLGMVEVDDKDHYSNKRLGLAGSLLEDLFRVAFRALVNNTTYSLEKAFKRNRKLAIRNSIRSNFLTERIQHAVATGAWIGSRQGVSQHLDRMNHLSSISHRRRVRSLLSTTQPHFEARDLHSTHWGRLCPSETPEGSNIGLVKNLSLTTKLTTQSDDALIEETLRKRGVKRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZZ9</accession>
    <name>A0A832UZZ9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDP-mannose 4,6-dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="4"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="337" mass="38029" checksum="0CE1F1EE82D9A50E" modified="2021-09-29" version="1">MKLLITGGAGFIGCNSADYFLGKGHDVSVLDNLSRAGTDKNLEWLQKRHPSVKFIKADVRTDQAVLDEEVSKADAVLHLAAQVAVTTSVTNPREDFDINALGTFNVLEAIRKSDNKPSLIYSSTNKVYGKMEELEVLEGEKRYKYKDIEGVDEKQNLDFHSPYGCSKGAADQYVLDYARIYDLKTVVLRQSCIYGTRQFGIEDQGWVAWFIIATSLGTPLKIYGNGKQVRDVLYIDDLVRCFEMVFDKIDKTLGNAYNIGGGPNNSLSLLELISQIESLHGREIEHSFHDWRPGDQPVFICDINKARNDFGWEPKVSPEEGVKKLFNWVQENKELFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V017</accession>
    <name>A0A832V017_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="8">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">lysS</name>
        <name evidence="9" type="ORF">H1011_00135</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="8"/>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00177">
        <property type="entry name" value="Lys_tRNA_synth_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002904">
        <property type="entry name" value="Lys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042078">
        <property type="entry name" value="Lys-tRNA-ligase_SC_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37940">
        <property type="entry name" value="PTHR37940"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01921">
        <property type="entry name" value="tRNA-synt_1f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00467">
        <property type="entry name" value="lysS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="43"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="551" mass="62335" checksum="88EE1288A9ED666D" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V024</accession>
    <name>A0A832V024_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="80" mass="8804" checksum="19EED4B127B1D567" modified="2021-09-29" version="1">MNPIIIAVVVIIVIFFLLRAIKKGRKEGFSKGVTAGKKIEDDKPTAVDSSGKEGKLAEAAKIINRPPKKDKKDKKEENED</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V037</accession>
    <name>A0A832V037_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lrp/AsnC ligand binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="9"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="75" mass="8465" checksum="A65A50508DD9D8DA" modified="2021-09-29" version="1">MVTAFILATTKTGKEREVLNDLKEIGEIKEVHNVYGDYDVFIKAESSSLDNLNEFLVRKIQSVPNIMMTTTMIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V045</accession>
    <name>A0A832V045_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">50S ribosomal protein L18e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_02320</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="4">
        <location>
            <begin position="34"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="115" mass="12242" checksum="B8BCC3C5C3EAB944" modified="2021-09-29" version="1">MKDSFATAIMGELERAGRGKDEKFLGNISRLMGKPRKNLASVNLSKLDRITKKGEVIVVPGKLLGTGSLDHKLEIYSFGASKAAVVGVEKSGGSISPILEIAKKHPKGTGVRIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V076</accession>
    <name>A0A832V076_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000005">
        <property type="protein sequence ID" value="HIJ99357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="221" mass="24109" checksum="AAA66A53E82F87E9" modified="2021-09-29" version="1" fragment="single">MITNRKGATAQRWMMIVIAGVVGLGLLVGIFFFLGNLLPKAEMESAGTYCYSGTGEKVRMQVSFEKVIQKMRDAQGDLLEGAEMTWKDVAVAFVPVYGQYKTAQNAWNVGTAAVETGAYDDAIAGMKGLEDQVNALMGDLEDNWPTRCRQGQTEKIDISMNADSLSYFLYQASVNAFYSLHGSTENAVTDFDIYEIAATVNGPGTFLMDGPCTKWIDGSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0D4</accession>
    <name>A0A832V0D4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2304 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019277">
        <property type="entry name" value="DUF2304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10066">
        <property type="entry name" value="DUF2304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="116" mass="13041" checksum="4EE8271230A1D8F2" modified="2021-09-29" version="1">MIAGIQAFGLALGLIMFYYAVKLYRQGKFKDRDFITWGSVAIVIVGVSVYPTVLDSVLSWLKIGRGLDALLVLGILGVYGFVFQVYIRNQETQRQITNLVRKVALELEQKGRKKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0I0</accession>
    <name>A0A832V0I0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="151" mass="17017" checksum="E31BE22255E662C2" modified="2021-09-29" version="1">MFTQVITLFGLVILGALISIGARRADLQGIELWLPFGLLVSYAYSPLWGFLIAFLMLLISWIVFPYGLQYLALTSVLLIPTFAITKFFPVTEASFFTVAMGIVIAYNIISNAAYIVLGANIVRIIKFAAFSIAFNWTVMYYFGWTFIQWLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0L1</accession>
    <name>A0A832V0L1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation-translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_02270</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="680"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="711"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="753"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="780"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="816"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="847"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="870" mass="94657" checksum="D3E817DFB6095BC9" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0Q3</accession>
    <name>A0A832V0Q3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Glutamyl-tRNA(Gln) amidotransferase subunit D</fullName>
            <shortName evidence="5">Glu-ADT subunit D</shortName>
            <ecNumber evidence="5 7">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 11" type="primary">gatD</name>
        <name evidence="11" type="ORF">H1011_02745</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Heterodimer of GatD and GatE.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the asparaginase 1 family. GatD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="5 7"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08962">
        <property type="entry name" value="GatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00586">
        <property type="entry name" value="GatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006033">
        <property type="entry name" value="AsnA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011878">
        <property type="entry name" value="GatD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040918">
        <property type="entry name" value="GatD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037222">
        <property type="entry name" value="GatD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18195">
        <property type="entry name" value="GatD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500175">
        <property type="entry name" value="Glu_ADT_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141300">
        <property type="entry name" value="SSF141300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="SSF53774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00519">
        <property type="entry name" value="asnASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02153">
        <property type="entry name" value="gatD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatD_N" evidence="10">
        <location>
            <begin position="6"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase" evidence="8">
        <location>
            <begin position="79"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase_C" evidence="9">
        <location>
            <begin position="293"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="431" mass="47375" checksum="D767F3E55B671004" modified="2021-09-29" version="1">MAQPGIGDKVKIKTRKASYEGILMPRSELSDKEHIVLKLDSGYNIGISKQDISKIEQVPESRKTRAPKVIVKAGKGLPKISVVSTGGTITSKVDYKTGGVSPFKTGEELLAGMPKLAEIVQINDIKQPFSLLSEDISHKDWSKIAKEVYSELKKDTEGVIVTHGTDTLHYTSAALSFMIEGLNKPIAVVGAQRSADRGSFDGLMNMLCATHYCLSDIAEVAIVMHAGSSDEYCIASQGTKVRKMHTSRRDAFRPINDEPIVKIWPDGNLVMTGTQYNERSSGNPKLLDKVEERVALIHSYPGARPEILEHYIDKKYKGIIIAGTGFGHVATQPLDKKESWLKAVTNTVDSGIFVGMTSQALYGTTDSMIYSAGRLLKNAGVTYLKDMLPETAYVKLAWALGNFKRSELEEKMLENISGEINERIQPGSFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0R0</accession>
    <name>A0A832V0R0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="4">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pcm</name>
        <name evidence="5" type="ORF">H1011_02825</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 4">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="213" mass="23657" checksum="D77972677C26C7B2" modified="2021-09-29" version="1">MKEELISYWKTYGVIRDKDVLQAFKDVPRENFVPEKFADQAYIDSPLPIAGGQTISQPSTVMVMTEELKVKTGQKILEVGTGSGYQAAILSKLVGSKGKVVSTEIVLELVDFARKNLERSGIENVEVIEHDGSLGYEKEAPYDRIIITAACPKIPEPLIKQLKNGGILLGPVGSILRGQEMIRITKKDDELKEEILGEFLFVPLRGKHGFKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0Y4</accession>
    <name>A0A832V0Y4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Methionine aminopeptidase</fullName>
            <shortName evidence="6">MAP</shortName>
            <shortName evidence="6">MetAP</shortName>
            <ecNumber evidence="6 7">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">map</name>
        <name evidence="9" type="ORF">H1011_03735</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="6 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="6 7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="6 7">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6 7">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="6 7"/>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01975">
        <property type="entry name" value="MetAP_2_arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028595">
        <property type="entry name" value="MetAP_archaeal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002468">
        <property type="entry name" value="Pept_M24A_MAP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018349">
        <property type="entry name" value="Pept_M24A_MAP2_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00501">
        <property type="entry name" value="met_pdase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01202">
        <property type="entry name" value="MAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 7" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="8">
        <location>
            <begin position="11"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="298" mass="32022" checksum="B60F69D2A2FA4F94" modified="2021-09-29" version="1">MIAMEKEAVEGFKEAGEISRKAKALIRKLVKPGALVLDLVNKVEDLIEKEGAKPGFPLNFSINSIAAHYTPPSGAELEVGEDDIIKIDTGVHVDGYPADTAITISTSESETHLNLIAAAEAALEKATEIVSPGILVGELGAVIQKEIESYGLKPIENLCGHSVERYNLHAGMTIPNVAGKGPELKEGMAIAIEPFSTDGVGRVSDAPDVYIYEYMRDVPTRNRDARKILAMARDDFSKLPFATRWLGIPELKSRIALKELVNSKAIYSYPVLKEAGGGLVAQAEHTMIVTADGAKVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1M9</accession>
    <name>A0A832V1M9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine biosynthesis protein LysX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lysX</name>
        <name evidence="6" type="ORF">H1011_00975</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimK family. LysX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009085">
        <property type="term" value="P:lysine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011870">
        <property type="entry name" value="LysX_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004666">
        <property type="entry name" value="RpS6_RimK/Lys_biosynth_LsyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02144">
        <property type="entry name" value="LysX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00768">
        <property type="entry name" value="rimK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="92"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="280" mass="31668" checksum="42DEB465222D79DC" modified="2021-09-29" version="1">MLRVGFLYSKIRQDEKLLLEEMRKRNLEIVKIDDKELNLSLEKQDFGIDILLERSVSHSRALYALKFFQSYGIPTINTFDVATVCGDKAYTSLALENHGIPTPKTRVAMTEESALQAMEELGWPCVIKPVTGSWARMCAKLNDKDAAEAVLEHKKVLGEYMHSIFYIQEYIEKPGRDIRAFVVGDETIAAIYRESEHWITNTSRGAIARNCEITEELNEICLKTAEAVGGGVLAMDVFEGKEGLMMNEVNYTMEFKNSVEPTGVDIPKKVIDYVVETARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1N6</accession>
    <name>A0A832V1N6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="298" mass="33230" checksum="6EAC16B5F14832E8" modified="2021-09-29" version="1">MWERNIEPAVVVTKWVRTFDDTQVAGLLTEEGDSVTIVDLKITLDEIIENLGEGWSTRIKIEEQSAGNGAILEMNKLTYEGEDALRGYDEIDRHLNVYPNLDLHATVTYNGNEYHIGPDYNKVVYDCPSFAQCSGNSYSVEWMFFPDDAEATYYVTDHDTGALNLESPVDIGYVIQYFNLDEEGRHMTREYEGGITNNAGKFTTKFYTTPDTDSFILAYDKQAGIPANQKDFETTLVDIEILDRLDLYNMGESIIVDTMMTPGEEQLPLGEAREGDEEGEPTDGLGGFDTGGVGGGLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V292</accession>
    <name>A0A832V292_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpl24</name>
        <name evidence="5" type="ORF">H1011_02635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Located at the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="2">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_A">
        <property type="entry name" value="Ribosomal_L24_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_L26/L24P_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="PTHR11143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="4">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="122"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="179" mass="20169" checksum="CD187342B4720101" modified="2021-09-29" version="1">MKTKWSSSWSGSTQPRKQRKYLHNAPLHIRQHLVTSNLDKKLRQKLETRSISLRKGDEVKIMRGSLKGIKGKILEVNLSTGRVHVEGQTRDKVAGGKAILTFQPSNLMVTAINTSDLRRFKRVEKSKRPEVKAEIPKKESEGKKEDSKESPAKSSSTKGEDSDTDKVKSSSKNTKEETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2I7</accession>
    <name>A0A832V2I7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="1">
        <location>
            <begin position="10"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="268" mass="29862" checksum="60F1511BC4A116E6" modified="2021-09-29" version="1">MEIDALKEKARQVRRDIVQMVYDAKCGHPGGSLSAVELLCSLYYNAAKVNPKNPKDESRDRIIYSKGHACPALYAILGDLGFFPKSEFKKFRKLGGLLQGHSDIAVPGVEMSAGSLGMGLSFAHGMALARDIDRKNHYVYAFLGDGECQEGQVWEAAMTAGSMKTRNFIAIIDRNQIQNDDFVKKTKDLSPLVEKWKAFNWHTIKVENGHDFEEILSALEDAKKLDGPVAIIANTRKGYGVSFMELNPKFHGMAPSDEEFKKAMEELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2K3</accession>
    <name>A0A832V2K3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="97" mass="11720" checksum="D5AE9252BC2DEDC7" modified="2021-09-29" version="1">MFWTKDPREKVRTILMNMYGAVTSKTPWGAPLWKKYDRNTKKLRRLIEKESSVRAMRFDIDEEKMSLEAILNRLDRMEPTQFREMSKIIYKTTRSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2N8</accession>
    <name>A0A832V2N8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0219 protein H1011_03705</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. UPF0219 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01409">
        <property type="entry name" value="UPF0219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004656">
        <property type="entry name" value="FabH-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00748">
        <property type="entry name" value="HMG_CoA_syn_Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III_C" evidence="2">
        <location>
            <begin position="219"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="347" mass="37077" checksum="58001382D54EAEC8" modified="2021-09-29" version="1">MDVGIVGYGSYIPYYRIKTEEIARVWGANPESIKKGLMVSEKSVPGPDEDAVTIATEASRNALALADIDPEKIGAVYVGSESHPYSVKPSSTIVAEAIEATPIMTAADLEFACKAGTAGMQICMGLVGSGMAEYGLAVGADTSQGAPGDPLEYTAAAGGAAFIIGKDNLLAKIESTSSFTTDTPDFWRRPGEAYPKHGGRFTGEPAYFKHIVSCTEQILKDSGYEVKDFKYFVPHQPNGKFPRIAAKKLGFTEEQVSPSLLVERIGNTYSGASVLGLAAVLDQAEEGDKILLTSYGSGAGSDSFILETTGRLEKVRGNAPSVESQIEHKHYIDYATYAKYRGKIKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V406</accession>
    <name>A0A832V406_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="95" mass="10803" checksum="DCBFD1037A11659D" modified="2021-09-29" version="1">MNHCESGGALSYISRKGGVYILFKDREESPMYFAYICPDCKHDEAGESDDFKKPYTLKCAECGIIIYKQEKAKKGGGRRKKEKPVEISEKKAFRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V432</accession>
    <name>A0A832V432_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Archease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_02495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the archease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002804">
        <property type="entry name" value="Archease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023572">
        <property type="entry name" value="Archease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036820">
        <property type="entry name" value="Archease_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12682">
        <property type="entry name" value="PTHR12682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01951">
        <property type="entry name" value="Archease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69819">
        <property type="entry name" value="SSF69819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Archease" evidence="5">
        <location>
            <begin position="4"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="144" mass="16423" checksum="0370C8DEF1162BB9" modified="2021-09-29" version="1">MKNYEYLEHTADAKFRAFGKTIEEAFSNAALAMFGIITDTEKIQPIVEKTVEVQGNGLPELLYEYLDELLFLLDTDNFILNKMKELKIKKEATGYTLKALAVGDLHMREDTKYLVSGNIKSMTYSEMIVDDRPEKCTVQVVVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V7S7</accession>
    <name>A0A832V7S7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RdgB/HAM1 family non-canonical purine NTP pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rdgB</name>
        <name evidence="3" type="ORF">H1011_00035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside-triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009143">
        <property type="term" value="P:nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="183" mass="20472" checksum="F4EBC355AC9D318D" modified="2021-09-29" version="1">MKYLFATSNASKFNEISEIFNDIGLELEHCEIEIEELQSDSFEEIALHSARKAYEQLGKPVFVEDAGISVDSLEGFPGPFTKYVFYTIGIAGLLKLLEGVSDRKAEYTSVLAYTDGNQEKVFKGSCRGSIAREYRGDGGWGWDPVFIPEGEDFTFGENYSSKKEHSHRSKSARALADWLKTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V818</accession>
    <name>A0A832V818_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cell division protein SepF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sepF</name>
        <name evidence="1" type="ORF">H1011_00765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007561">
        <property type="entry name" value="Cell_div_SepF/SepF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038594">
        <property type="entry name" value="SepF-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04472">
        <property type="entry name" value="SepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="145" mass="16239" checksum="0433C6AF5F92EEA3" modified="2021-09-29" version="1">MMGENMMAAFKNIFRRSSNSSTPTSVTREPKFMEIDWKGHEPQSSTSIRVLSMNDFSDVEGVLDHLRDRNNIIVLKVKPRLMQEKLELKRALKRIQRTCQAIGGDIVGIKEDVILISPPSVGIVRVGEIAESSQVSAKPEETVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V837</accession>
    <name>A0A832V837_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">dCTP deaminase</fullName>
            <ecNumber evidence="3">3.5.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dcd</name>
        <name evidence="3" type="ORF">H1011_00915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.13" evidence="3"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="2">
        <location>
            <begin position="63"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="162" mass="18163" checksum="50D12EAE25E6229E" modified="2021-09-29" version="1">MILGNSEIKRLIEDKKLIEEHEEKNIQGAGVDFRARTFYRPSGDTKVHKESRTLPEISEISGDTVSIKPNELILVETIEKVNMPSDIAARILPRSTLCRCGVYLLTAFVDPGFSGRLTVGLKNMSNHSFELEKGARIMQVMFEKTEGDTVDYDGRYQGGKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V847</accession>
    <name>A0A832V847_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aspartate--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="6">AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">aspS</name>
        <name evidence="8" type="ORF">H1011_00995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="PTHR43450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="7">
        <location>
            <begin position="143"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="6">
        <location>
            <begin position="198"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="219"/>
            <end position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="360"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="367"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="408"/>
            <end position="411"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="437" mass="49692" checksum="630921A02E0C2784" modified="2021-09-29" version="1">MDLDNIGKLRKTHYAAEIVPTLDNKDVVLMGWAREIRLLGNLVFVVLADRSGDCQVTFLPKTKKVFETAQKLNREDVIAIKGKIKKSEKTTRGVEVLASEILVLNKSKTPLPLEITEKTPSDLDTRLNSRVLDLRKPRNIAVFKIRNQILESAREYFTEQGFMEIESPKIIASASEGGAALFPVSYYGKEAFLRQSPQLYKELMTACFERVFEIGHVFRAEPSDTIHHLSEVTQMDIEMGFATEEDTWEILEGLINRIYSDISKKQKDALGVLGQKIKVPKMPFKKMTYDDAVNLLNKKGTKFKWGDDTSREQEKLLTDHSGGPVIVHDYPMEMKPFYIAHHENNPKLSYGFDLLIDGIEICSGGRRIHEAEQYIENLKAKGLNPDSFADIIKFYEYGMPPHAGWAIGVDRLTMLISGVDNIRETVLFPRDLKRLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8A4</accession>
    <name>A0A832V8A4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="10">5.4.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">glmM</name>
        <name evidence="10" type="ORF">H1011_01465</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="10"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03087">
        <property type="entry name" value="PGM_like1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024086">
        <property type="entry name" value="GlmM_arc-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03990">
        <property type="entry name" value="Arch_GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="7">
        <location>
            <begin position="3"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="8">
        <location>
            <begin position="149"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="9">
        <location>
            <begin position="253"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="6">
        <location>
            <begin position="365"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="442" mass="47621" checksum="4B9875470DA2944B" modified="2021-09-29" version="1">MALFSTTGIRGIANIDITPEFMLDLGKTFGTMVGPCKVLVARDTRTTSEMLSNSLIAGLLSTGCDVFDTGIAAGPVVNHAAQSAYDAGVMITSSHNPPEYNGAKFILKGGKEVGEKEEIEFEKILNSGKFTTVSWDKVGSYSECDSVSPYIMDALALVDLEKIKSKKFRVVADPGNGAQIDAVPRILKELGCEAIIINGENTGKFGRLPEPRPETLSELFEEVRKQKADFGVAFDCDGDRAVFCNEKGEFIMGDVTGSMIADSLAEKGDKIVTPVATSSIIDDVASNSGAEIVRTRVGAKYVSDSVISGGAVFGFEENGGCIFPKLSPGRDGSMTLITMLDLLTDYDSFSSAVSTLPKYFQLKAKVECSDDKKADTMKRAMERAKQDGLKFSDIDGLKFFEEDGWILVRASGTEPVLRVFSEAKTESRAQELLERGKALLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8S3</accession>
    <name>A0A832V8S3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein translation factor SUI1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yciH</name>
        <name evidence="6" type="ORF">H1011_02655</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11567">
        <property type="entry name" value="YciH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005872">
        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037511">
        <property type="entry name" value="Transl_init_SUI1_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="SSF55159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="5">
        <location>
            <begin position="29"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="98" mass="10602" checksum="EC6950E4B0E19312" modified="2021-09-29" version="1">MAEDLTCSVCGLPKELCLCEDVKREQTTVTIRTEKRTYGKLVTIVEGVSADMLKQVASELKKACATGGAVKNGTIELQGDNVRKLNTILPKKGFTVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8V2</accession>
    <name>A0A832V8V2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="284" mass="33238" checksum="55E28BBD6D91BB3E" modified="2021-09-29" version="1">MFGRKTTKITGKVGVQEYPYIDGRLKTLFRENGILDTRDNRIQNILLVDPWWNDDADTIFGTPFLLNHLLQGQANIYALYSKPVDMDYFEKLKEAVNKGYAEEDVGFDAKNIFIAGGINPEDGRRGFGKTGWRLERDSFQLVFKPKQQNNITKGAFELYNYILEEGGILFATLEGGIVRKTENIMCGWNYGRRRAEPEERMAPIERVFRVAPELSRVERYAGGPFAGDERNFIQRARHWKIYVKCDRRRLRRGNEEIWRFLRDKRTELRPLRILPSQDYPGEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8W0</accession>
    <name>A0A832V8W0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF378 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007211">
        <property type="entry name" value="DUF378"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37304">
        <property type="entry name" value="PTHR37304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04070">
        <property type="entry name" value="DUF378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="66" mass="7270" checksum="3EE537FC6DB8C777" modified="2021-09-29" version="1">MAKNNRLDMAALGLVILGGLNWGLIAAFQWDFVDALLGSLPTLQRLLYLLVGLSALYMLYNTVTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X4U7</accession>
    <name>A0A832X4U7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Holliday junction resolvase Hjc</fullName>
            <shortName evidence="10">Hjc</shortName>
            <ecNumber evidence="10">3.1.21.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hjc</name>
        <name evidence="11" type="ORF">H1011_00055</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the Holliday junction resolvase Hjc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="10"/>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00523">
        <property type="entry name" value="archeal_HJR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01490">
        <property type="entry name" value="HJ_Resolv_Hjc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002732">
        <property type="entry name" value="Hjc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014428">
        <property type="entry name" value="Hjc_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39651">
        <property type="entry name" value="PTHR39651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01870">
        <property type="entry name" value="Hjc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004985">
        <property type="entry name" value="Hlld_jn_rslvs_ar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8 10" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="10">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="140" mass="15841" checksum="C73EA474C7C0DF2D" modified="2021-09-29" version="1">MVIKDKYGKGARAERELIEMLWERGFAALRVAGSGVSRRPCPDVVASDGKMTFAFECKSVAGDYVHLSYDEIVKLITFSQTFGAKPWIAVKFGSKDWVFLDMAKIQMTKGENFKVSKSFAYDDGKRLDELIEMNRDHSDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X516</accession>
    <name>A0A832X516_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">V-type ATP synthase beta chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">V-ATPase subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">atpB</name>
        <name evidence="9" type="ORF">H1011_01175</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 6">Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00310">
        <property type="entry name" value="ATP_synth_B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022879">
        <property type="entry name" value="V-ATPase_su_B/beta"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43389">
        <property type="entry name" value="PTHR43389"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039114">
        <property type="entry name" value="V-ATPsynth_beta/V-ATPase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="7">
        <location>
            <begin position="129"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="455" mass="50315" checksum="5F975CE8C955672A" modified="2021-09-29" version="1">MKEYKTINQVAGPLIFLEKTHDVGYGELVDIKLSNGDRKRGQVLDTSKDIVVVQVFGETVGMDKKASVKFTGETIKLGVSEDMLGRVFSGFGVPIDGGPEIIPEERLDINGAAINPYSRSSPSEFIQTGISTIDGMNTLVRGQKLPIFSGSGLPHNDIALQIARQAKVPGQEGEFAVVFAAMGITNEEAKYFIKDFEETGALEHAVVFLNLANDPAVERIITPRLALTTAEYLAFEKDMHVLVILTDMTNYCEALREIGAAREEIPGRRGYPGYMYTDLANLYERAGIIHGRKGSITQVPILTMPGDDITHPIPDLTGYITEGQIVLGRELHRSGIYPPIDVLPCLSRLMNSGIGKGKTREDHKDVSNQLYAGYAEGRELRGLVSIVGEEALSDRDRRFLRFADAFENLLVKQGGDENRSIEDTLNLGWKMFADILDEKDLTRIDPEEIKKRLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X536</accession>
    <name>A0A832X536_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GDP-mannose 4,6-dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="4"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="292" mass="31616" checksum="ADCB1906E5D6FFA6" modified="2021-09-29" version="1">MKVLVTGGAGFIGPYLVGALKNTGHEVVILDNFSSGNKSNLEGSSAKIVEGDIRNLENVESAMEGCELVFHLAAQSSVQRSMENPEEDSEINVLGTENVLEAAEKAGVKKLVFFSSAAVYGNPLEFPVTEETETKPISPYGESKLAAEKLCAESSIPTFILRIFNIYGNGGQGVITKMLVEANLGRSPEIYGDGEQTRDFLYVKDLVRACILCLENESGKSTILNIASGEETSINDIVSAMENALGKELNVVKTTEKEGDIKRSWTSISRASEKIGYRPEYSIEDGIKDMLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X555</accession>
    <name>A0A832X555_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Purine nucleoside phosphorylase</fullName>
            <shortName evidence="1">PNP</shortName>
            <ecNumber evidence="1">2.4.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mtnP</name>
        <name evidence="3" type="ORF">H1011_01790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Purine nucleoside phosphorylase involved in purine salvage.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Dimer of a homotrimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000010">
        <property type="protein sequence ID" value="HIJ99539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01963">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="PTHR42679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01694">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="2">
        <location>
            <begin position="6"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="1">
        <location>
            <begin position="55"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="210"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="1">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="1">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="264" mass="29160" checksum="4E7CECC2C5EE384A" modified="2021-09-29" version="1">MENQVDIGIIGGSGVYDAEFLKNSEEITLESKYGSPADSYLVGEYLGKQVAFLPRHGKDHALAPHQVNYRANIDGFRQLGVRRIIAAQAVGSLKEEYTPGDLAFTDQFIDRTLGRDSTFFDEGKVAHVSMAEPMCQSLREILIKGAQKLELAHHEKATYVCIEGPRFSTRAESELFKSWNADLIGMTLVPESVLAKEASICYAPVSMVTDYDCWKEGHVVSHEEVISVMEQNVGKIKKLLSEVIAKIPDERSAECENAMEGATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X585</accession>
    <name>A0A832X585_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="218" mass="24293" checksum="1A70A4B20A587AC5" modified="2021-09-29" version="1">MSWLDDLMGTGDEGQYPSHRLAGALGILLLIIYASLGLSYAPFTALWARLLELLTAVKGNYVMMLSLAPLYLNWVSSDYFQERRGATLGNAASNGFTGLWVAFDWGRAAYVGYAVTKSAAYFSAKIFLAFTMAVYGGLVIFEAARGKRIARIIGRVREISFFAILLTPVAYGVYPFDKLTLLTLIVFYPLFYGLIEFINFFVLPVPKTEAPREEDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFJ7</accession>
    <name>A0A832XFJ7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="47" mass="5192" checksum="9750DDAD30CF0F85" modified="2021-09-29" version="1">MKNPHYICTGGCGGVSEEQKNCGAEDCKNYDMPLEECKCTDGRHIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFL7</accession>
    <name>A0A832XFL7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PhoU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoU" evidence="1">
        <location>
            <begin position="77"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="261" mass="30379" checksum="754241C32CF50EDF" modified="2021-09-29" version="1">MNILKGISRSFKALGDMYYIWKERPFSTFREISDIYHKRPLLDSAYVSAVEMLKRDSYMFSEACAAILDDVTIRTPKNKGAIITTLESEDERINLYERDIRKHILKYLAENSAPDVKRSLVLTSLVIDLEQLGDYTVEMARLTLLNPHKLDNNLHMKTMRNYRDRLNVMFSLSIEALSEKSKKNASQVSKLNQVLLADSEKFLRKLEQGKSLRMADVMFYILLTRYFQRVGGHLENISTGIFQPFQYVGFKRHTKHKPKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFV3</accession>
    <name>A0A832XFV3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3096 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021446">
        <property type="entry name" value="DUF3096"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11295">
        <property type="entry name" value="DUF3096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="38" mass="4218" checksum="664C0E7601804264" modified="2021-09-29" version="1">MIFFGVLIFLYPNSLNFLVASYLILVGTVKLITKIKGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFX1</accession>
    <name>A0A832XFX1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.</text>
            <dbReference type="EC" id="3.1.21.7"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007581">
        <property type="entry name" value="Endonuclease-V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28511">
        <property type="entry name" value="PTHR28511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04493">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="219" mass="24391" checksum="4841E8C4414332DF" modified="2021-09-29" version="1">MSKFFPDKITILSASELQKKFHEDLIIEDDLPIKIETIGGVTSYSRGKIIKVSLAILKVDENYSKFEVLKQDFIEEQSKIPDLPTFGGFREGRAIADSITSFDIPDVLMIKGHGINHPRKFGIACHVGLSMNIPTIAVSSDLLCGEMKTIDGKNVIVDEEEIVGEVVKTSATSPRLYVSPGHRVSIRTAAEIVRKTTLEKMPEPLRVANEQLIQKMRQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG32</accession>
    <name>A0A832XG32_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="46" mass="5221" checksum="3F3CE56B38F3D478" modified="2021-09-29" version="1">MVESSSSKKKVKKAEKDPFKEVYVELKKYRKGVPPEESEPSECACS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG38</accession>
    <name>A0A832XG38_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglutaminase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="120"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="212" mass="23714" checksum="76D3B76B0A4E2521" modified="2021-09-29" version="1">MKKLLVMAVLLVAPMMFFGISVEKSAAMAPFTASVSEAEYEWSANRESFSSIYLYQTENCESGGVFRSRTKNVQLSGPTALLVASELSTGSQMENVESMFNYVSNMPYLRYSEWRNTEDILKTMNGDCADKSVALVSLLKGAGFESYVVYGDEIDGYSHAWVSVNIDGYWLQLDATTNDMFSIYKCIEEGCDFSSHYKIVGFFDNSESYDCS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG54</accession>
    <name>A0A832XG54_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_03285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001976">
        <property type="entry name" value="Ribosomal_S24e"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01282">
        <property type="entry name" value="Ribosomal_S24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="82"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="139" mass="15662" checksum="F1086C883175FEF8" modified="2021-09-29" version="1">MNIKILNEKENKLIGRKEYEILVENPGPTVSKESLLPEVCKALKCEEGLMVILQINQVYGAKHSIARVDVYNSEDILKQYRREEKSVEEKPESEEAPSETSEESPKESGKKTEEAKEDSPADEKPAEEAKEADNAAEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG71</accession>
    <name>A0A832XG71_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="114" mass="13490" checksum="926D091A8DD31AB1" modified="2021-09-29" version="1">MMNKRKLAEKRNDTQRLYHVPGMANITNRKRNAVFISPSNSLEHEIGKMKVCYELRKEKMQFITEAVCNKTQKRRDVVCLDDGMIFEIETDKKRAERFKDQKGVVVIKLWKEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHB8</accession>
    <name>A0A832XHB8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II/IV secretion system ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="262"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="105"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="639" mass="72039" checksum="84DF74D5EFA1F047" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHC6</accession>
    <name>A0A832XHC6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Isopentenyl-diphosphate delta-isomerase</fullName>
            <shortName evidence="7">IPP isomerase</shortName>
            <ecNumber evidence="7">5.3.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Isopentenyl diphosphate:dimethylallyl diphosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Isopentenyl pyrophosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Type 2 isopentenyl diphosphate isomerase</fullName>
            <shortName evidence="7">IDI-2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fni</name>
        <name evidence="9" type="ORF">H1011_00490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>isopentenyl diphosphate = dimethylallyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23284"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="5.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6 7">Homooctamer. Dimer of tetramers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the IPP isomerase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="7"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02811">
        <property type="entry name" value="IDI-2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00354">
        <property type="entry name" value="Idi_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011179">
        <property type="entry name" value="IPdP_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43665">
        <property type="entry name" value="PTHR43665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003314">
        <property type="entry name" value="IPP_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02151">
        <property type="entry name" value="IPP_isom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="5 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 7" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0521">NADP</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_dh" evidence="8">
        <location>
            <begin position="5"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_dh" evidence="8">
        <location>
            <begin position="174"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="6"/>
            <end position="7"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="95"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="65"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="265"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="286"/>
            <end position="287"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="346" mass="36714" checksum="1DAA068482FCDD2C" modified="2021-09-29" version="1">MSTSERKLDHIKIVSNERVEAREKTTLLDEVELIHNSLPDLDRDSVDTSTEIFGKKLKIPFLISGMTGGHPNAEKLNLALAEAAEAAGVAFGLGSQRAMLEDKSLSQTYKVRSVAPNTLIFGNIGIPQISDYSPSDISSMLDDVGADALAVHLNPLQESIQPEGDVNMEGLAGSLKDLIKSLGFPVLVKETGAGISKDVAKILIDCGVSAIDTGGAGGTSFAAVELFRKDDFELSEFWDWGIPTAASILEIRASSKEILLIATGGIRNGLDAAHALALGANAVGMAGPMIKAAAKGSSEVLIEIEKVHKSLRTAMFLCGASEVSKMGRDKTVLTGSLRSWQKQREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHE9</accession>
    <name>A0A832XHE9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000006">
        <property type="protein sequence ID" value="HIJ99360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="65" mass="7190" checksum="46F1C54018990CE5" modified="2021-09-29" version="1">MNERGIQLTLQLVIVIILLAITLAVILTFFLGSTDIMFGTLGETVSGTAEEFQKQVPDYLTKLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHI2</accession>
    <name>A0A832XHI2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_01490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="295" mass="32106" checksum="846F09313616D8D3" modified="2021-09-29" version="1">MVSFDALPVFSAFVLSIVLTVIFIKRFKRIGRVSEDIHKEGRPMQANFGGIAVAAALGTILLGMYLVTSSAIYMTLTLVFLISASVGLLDDLFRFSPYQKLALSAIPALPLILFWGFGVYQVLAVVVAIVVLSNWTNMLAGFNGLEAGMGAIALFFLGLNTWNFEVRTALFAYSLALLGFLIFNRYPAKVFPGDVGTLPIGAFLAASVALGAPLIALAILSIPYFLDMSLKLATMGVASSKNIVPTRVENGILVPQKSYLSLTNLILRIKRMREWQLVTIYWLVEIALGMVTLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHJ0</accession>
    <name>A0A832XHJ0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lrp/AsnC family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_01640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="163" mass="18969" checksum="006D8301D043F1C9" modified="2021-09-29" version="1">MTNLDKKNCIILNMLQENCRVSLTDMAKRVGLSVDSVKKRVKKMENSKIFYPRVQIRPRHFGFENIVDVKIKLYNYTDEDLNSFIKFLKENQQVPEVFLVSGEWDVSLVIMAKNSEDLGELTSSIRKRFGNIIREWSESLTTIAHKFETYDMLELMGHGSGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHR1</accession>
    <name>A0A832XHR1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">pyrG</name>
        <name evidence="12" type="ORF">H1011_02995</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="3"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="299"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="380"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="379"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="505"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="146"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="186"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="532" mass="59333" checksum="DE76C8E44590180D" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHS4</accession>
    <name>A0A832XHS4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">K(+)-insensitive pyrophosphate-energized proton pump</fullName>
            <ecNumber evidence="10">7.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Membrane-bound proton-translocating pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Pyrophosphate-energized inorganic pyrophosphatase</fullName>
            <shortName evidence="10">H(+)-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">hppA</name>
        <name evidence="11" type="ORF">H1011_03270</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>diphosphate + H(+)(in) + H2O = 2 H(+)(out) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="7.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="10"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:pyrophosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="PTHR31998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="349"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="379"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="444"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="481"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="549"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="574"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="site" description="Determinant of potassium independence" evidence="10">
        <location>
            <position position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="662" mass="68256" checksum="D9B89569CA475AA9" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHU3</accession>
    <name>A0A832XHU3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps4</name>
        <name evidence="10" type="ORF">H1011_03590</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_A">
        <property type="entry name" value="Ribosomal_S4_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005710">
        <property type="entry name" value="Ribosomal_S4/S9_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022802">
        <property type="entry name" value="Ribosomal_S4_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018079">
        <property type="entry name" value="Ribosomal_S4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01018">
        <property type="entry name" value="uS4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00632">
        <property type="entry name" value="RIBOSOMAL_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="9">
        <location>
            <begin position="5"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="8">
        <location>
            <begin position="102"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="154"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="169"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="219" mass="24672" checksum="40A8198F2C6398F9" modified="2021-09-29" version="1">MGDPVKTRKKYSTPSHMWIQERITRETKLSGKYGLKKRQEIWRAESLVKKFRSLARQIAGIRGDSSAEQERLLGKLLRMGVIGSDSKLNDILTLDATDFLERRLQTIVLKKGLASTAKEARQIVLHGFVTIDGERRRVPGSLLSVNEEDSIAYVGPSREQTVQKPTRALEAAADEKEDKSRDDKALEEKPKEVVEEKPKEVVEEKTKSSPAEEKKGDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIG5</accession>
    <name>A0A832XIG5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="317" mass="34120" checksum="293DC5A34A9A3D93" modified="2021-09-29" version="1">MRVKLGGSEGYKNYRSLWMDGLTVKVIDQRSLPFSFKIAELKTAKETLSAIRDGVIRGSLSTGAASAYAVAQSANEFDGSAYELFRLSVYGSADLFKDEFDSPDVSLSVGKLVSSIKNLDSIELAKKAALAAAEEVSSTYLDVCKRIGLRGGNLVSNGSKILIHCNGGALGSVDFGTALAPIRSAHILGRNFQVYVDKDCPGTNSWELSQEGISVAAIPPFGTGHVMRSGEIDICIMAAEKADTNGDIYSYPGTYETAVLAKEHSIPFYVALPRSSVDISGKKLEENSSFVPSDYITAYITEYGLFRPENFKDLLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIV6</accession>
    <name>A0A832XIV6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polysaccharide biosynthesis C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_03000</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="430"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="341"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="496" mass="55142" checksum="EEDCA4B90C452310" modified="2021-09-29" version="1">MSKSRKISGEVAFSYFIIALNVVLGPILIILLTRTLGVELYGVFMLLVALISLLSLVLQPGLSQYLVARLPGMPKKKWPQIFHSILAFELIFLSSALLLFYFTPLRGWFLEFNRLSGYSELFSISLFITFTATLIVVYEFYFKAKQRINFSNLMGFMRGKGWVIFLLAFFALYRTLSLIDVLMIWLVSNIAVLLIFMWASRSDIALFIRSGGIKFSAAKQGFWFGFPLILMSVMTWVIMTSDRYILNYMGSVELVGLYAVPYALFSLIFNLGNAPNNVLLPYFSESRINDRKKYSFYVSAALKYGLLVLVPGTVGAYILGAELISLLSGNAFMASVPLVATLMAFPLFALLGAIGTNVLMIHGKTKFIGLIYSFGALLNIVFNIILIPLYGMHGAAVATVISYFVIAILVFYPASGLVRFDYRYVKIPHILLSAAIMGISIAFIHPASAVSKLMTIALGVAVFGASAYATGVFNIKEKTLFRSIMSLPFRRKASKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIW9</accession>
    <name>A0A832XIW9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA-directed RNA polymerase subunit Rpo7</fullName>
            <ecNumber evidence="5">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DNA-directed RNA polymerase subunit E</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpo7</name>
        <name evidence="5" type="synonym">rpoE</name>
        <name evidence="7" type="ORF">H1011_03275</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="5">Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="5"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00865">
        <property type="entry name" value="RNApol_arch_Rpo7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036898">
        <property type="entry name" value="RNA_pol_Rpb7-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004519">
        <property type="entry name" value="RNAP_E/RPC8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046399">
        <property type="entry name" value="RNApol_Rpo7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045113">
        <property type="entry name" value="Rpb7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005576">
        <property type="entry name" value="Rpb7-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12709">
        <property type="entry name" value="PTHR12709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03876">
        <property type="entry name" value="SHS2_Rpb7-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88798">
        <property type="entry name" value="SSF88798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00448">
        <property type="entry name" value="rpoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="6">
        <location>
            <begin position="82"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="194" mass="21859" checksum="1E413E492EEAC7EC" modified="2021-09-29" version="1">MYQIVRIEDMVRVPAEHFNEELEVTLKNILAEQYEGKLDREVGSLISVLDVKSDGIGRVIPGDGAAYYNASFRALTYKPELQEIVEGDVIEIVEFGAFIRLGPLDGLVHVSQITDDYLNYDEKGQKFVGKESKKTLAQGDKVRARIVTISLKKAKENKIGLTMRQPGLGKLEWINEKEPVPTEKKALKKKEGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIX6</accession>
    <name>A0A832XIX6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acylphosphatase</fullName>
            <ecNumber evidence="1">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_03430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="3">
        <location>
            <begin position="3"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="89" mass="9996" checksum="1B9B96DB455E19B1" modified="2021-09-29" version="1">MKRVHLFISGKVQGVYFRTFVKENAERIGVKGWVRNTEDKVEAVAEGNDNKVSVFIEVCKDGPTAAVVEKVEVKTEDYAGEFSEFGILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIZ5</accession>
    <name>A0A832XIZ5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative metal-binding motif-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021655">
        <property type="entry name" value="Put_metal-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11617">
        <property type="entry name" value="Cu-binding_MopE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="328" mass="35153" checksum="08E395A0C7D2FE73" modified="2021-09-29" version="1">MAVNKGLIIGGLVLVLVVVGYMFFGSGAETGGKFVGVFGPAGPQIIEYRTPIDLQCASFFPAGSRDFDTYLQLSDCPNGQLDCSAGEQCMGFMEAVCSISTEAQCNLNMNCNWDSYVRKCGLANPSNTGGPYCFTQTSAQKARVYDYEKVRFDECRKLAHADPDGDGYPTGNLVTAGTTYPWQVVWSKIFQEDEIDLAWNNGGWDCAGENSEIFPGAKDVCDGMDNDCNGVVDNDPLAVATTLYLDGDSDGYGDASQSEIFMIGPNTCVDTTGYVTDSTDCNDDSASAYPGATEVCDDIDNDCDGVVDEGTFDGMTKDEWVEIFGGCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL05</accession>
    <name>A0A832XL05_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system F family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_00325</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="183"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="74"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="276" mass="30570" checksum="3D823C1F549BE6F8" modified="2021-09-29" version="1">MDIKNLSVKTQHIVLAISAAFAVILMIIPFAIGKTDLLPPAFSVAILFVFLPYSYFSYTSRKEIEEIEDKLPAFLRDIAESRKSGLTLPQAVSKSSKTDYGVLSKYVKKMAVQLSWGVPFTEALRRFSTKSRSRFVQRAIAIIIETQMSGGALSETLDAVANDARIIKEAEAERKTKLQQQTVIMYAIFFLFLMIVISLQRLLVPLVFSGGFAIASIDPEGVLSFYQGIFFSMIVIQAIFTGLIAGQIADDSVKLGLKHSAIFLVTGVMASWIFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL09</accession>
    <name>A0A832XL09_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="7">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">hisS</name>
        <name evidence="9" type="ORF">H1011_00425</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="7"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="8"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="421" mass="47541" checksum="8C4FAB4FA35C86DB" modified="2021-09-29" version="1">MAFEKAKGTRDFSPQEMSLRNYVFDTIRRVYKTYGYQELETPAFERWETLSAKSAGGEDVSKEIFRFTDYGEREMGLRFDLTVPMARYIANNPMIPRPFKRFQIGRVWRYDQPQAGRYREFWQADVDVVGSTEVEADLDALGAVVASLKALGFKDFTVEINNRALLEELAELFEIPRVKCPDLFRCIDKLDKIGMNSVKKEIADKGIKNVDKFLKFIETSGMKELEEKLPESAELAKTKELLKASKALGLGKWLKLTLSMVRGLAYYTSFVFEIKVKGMEKYGSVGAGGRYDDLIGVYGKSDMPATGCSIGVERIIEIMKERKMVDIPKTETKVLVIPIGNTFKDAAKIVQQLRDAGIPSTIDLMKRGPSKLFSYANSLGIPYSLAVGEKEVNSKKYTLKNMESGKQEELGIDKIISKLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLA1</accession>
    <name>A0A832XLA1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="229" mass="23966" checksum="AE53CA6C5D0C2D6D" modified="2021-09-29" version="1">MAYGEYKEKTTATSKDEVLTIEGKVRHKLGRNNKGTLVITGNVGDVVGRDNEGTITITGNAGDNVGLDNKEIITVNGNARNGVGTDNKGTITITGNAGNGVGESNKGTIIVNRNAGKGVGSGNEGTITVEGNAGDNVGLDNKEIITVNGNAGNFVGESNEGTIIVKGDAGERVGHDNHGIIIVEGTIKELHKKASGIIIAKDVKKDHGILWFKRDSNEVRFEYINARST</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLG5</accession>
    <name>A0A832XLG5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TrmB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="36"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="297" mass="34343" checksum="1BA206A3736AE0E3" modified="2021-09-29" version="1">MGNMLDPEFRILLKEEYDFRENHLILLSHFMSKKGKKLSAETLWTETEVPKGRIYEFLNDLVDWGFLDVEYKKPKTYSIRNLKEALQNAINRKERKLTQTEKKTLEVANKIEKAWRAELGEKTGSITIISSPEEFYIKAREMLMDSTTAKISERTPLLFLSTERNSTWRRRTYEIMIDMTESKRLDLKYIFSLENVRKVASESENADEVIKSLKGALENENLACRYVKGTGIESMLIVKDRALLGMVSPKTGSVENGLYIESKEMVDSLDKMYDLIFEEAEPLGLKALQILGKALEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UL88</accession>
    <name>A0A832UL88_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002760">
        <property type="entry name" value="O_anti_polymase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01901">
        <property type="entry name" value="O_anti_polymase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="318"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="392" mass="43136" checksum="5AFDAD1426820288" modified="2021-09-29" version="1">MKAKKFDLMGPVLVPALYAVFLLLAGISFLLGLTPTKPSLLGFLFILISTPFYFAGMKAANKVYGKKVALLTPKLLILLSVIFYTFVVQGVFHPGLPVSALFAGLAGLLTYYLLSKWKTSNKSLDRIPYYFLLSGIAFILLTIYDVGAIPLFEGAVRYALLDNVYWGLGYVLYFIGYMLLLPQIKTGKSLFALIFVSSLLFILMAFRTELLVILIAGIASGYYRQKLSLKSVLAGFASALALIIILGYIFMPLLSPVEILLYRAGTTYVVFDEIAQESGLGGIEHGALSFKGDPRFYVGKMLLGLHRNITSTLLGPPVIDFGLAGAAVFMFLLAFILQLSRKSIASKSLVLQPFYPILLAYSVVWIETGLDQLDLVFFVAFFTAYLLVTSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULE9</accession>
    <name>A0A832ULE9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004557">
        <property type="entry name" value="PrmC-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00537">
        <property type="entry name" value="hemK_rel_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="25"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="180" mass="19984" checksum="D35296BD6EBAFEFE" modified="2021-09-29" version="1">MKTFYRDFVFEVSDDVYSPREDSFLIADSFELKGSEKVLDLGTGSGILAIIAASKGCEVTAADINPEAVKYAKKNAERNQVSIEVIESNLFENIPGDFDIILFNLPYLKITEEPEKAIDLSYNSPGTIEGFLREYKEHLKPGGRAIVVSSSLSGIKPESLGKIIARQKLPFEEIFVVELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULG1</accession>
    <name>A0A832ULG1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CTAG/PCC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015419">
        <property type="entry name" value="CTAG/Pcc1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09341">
        <property type="entry name" value="Pcc1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="75" mass="8275" checksum="9660DCC986EEED98" modified="2021-09-29" version="1">MYTTIIEVEADDADAIVSSLKPDLDDAIRFKADLRSEDGKIVLEFEARDAAAMRAAVNSYLKLVGMLVDSEPEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UM18</accession>
    <name>A0A832UM18_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">30S ribosomal protein S17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsQ</name>
        <name evidence="3" type="ORF">H1011_02645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="121" mass="13521" checksum="EA30DD5CFE11EABC" modified="2021-09-29" version="1">MVKEEEKSAKAAPKKAAKKATEKKVPSTAEPEALSIGFSTTGYPFRAIVVSDKMRNSVVVVRQFVRKITKYERYEKRTTRLTVHNPESIGAKTGDEVVVQNCRPISKTKSHTIISVVERSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UMA7</accession>
    <name>A0A832UMA7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable transaldolase</fullName>
            <ecNumber evidence="9">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fsa</name>
        <name evidence="9" type="synonym">tal</name>
        <name evidence="10" type="ORF">H1011_03310</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the transaldolase family. Type 3B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="9"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00956">
        <property type="entry name" value="Transaldolase_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00494">
        <property type="entry name" value="Transaldolase_3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022999">
        <property type="entry name" value="Transaldolase_3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004731">
        <property type="entry name" value="Transaldolase_3B/F6P_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033919">
        <property type="entry name" value="TSA/FSA_arc/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00875">
        <property type="entry name" value="fsa_talC_mipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00958">
        <property type="entry name" value="TRANSALDOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="214" mass="23466" checksum="8863A147E2BF51C3" modified="2021-09-29" version="1">MKFFIDSADIEEIRKAKSYGIVDGVTTNPSLIAKIGTERDETVKDILAESDWPVSIEVISTDTEGMLKEAYEIAKLGKNAVVKIPMTLEGLAAVKELSAKGVKTNVTLIFSANQALLAAKVGANYVSPFIGRLDDKGEDGMQLVRDIVQIYRNYGFETEVLVASIRSKEHVLQAALTGAHVSTVPMKVLEELAKHELTDAGLAKFLEDWKNRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UP95</accession>
    <name>A0A832UP95_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="67" mass="7472" checksum="CF6D7E53827533D0" modified="2021-09-29" version="1">MTTRKSRKIVIQITIILAFIFSLVIAYIARGTGMSSMLLIFMAGLQVIVLLSILYVLETVIEIIEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPT2</accession>
    <name>A0A832UPT2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="143" mass="15436" checksum="36333CB5EAFBF288" modified="2021-09-29" version="1">MCPKNIPMVFYSAPEGELSAISGTGQNNFGRRNNGFLVVVGDAGSDSGFLNSNIIYISGDAGENLGGENKGTIIVEGSIESLHEKASGTIIASEVSDSKGRNWLEPDGRKAKIIIAKVKKKLMKKGLKKELKRQRLELSWVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQ39</accession>
    <name>A0A832UQ39_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydrofolate reductase</fullName>
            <ecNumber evidence="1">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_02815</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017925">
        <property type="entry name" value="DHFR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000194">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00075">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHFR" evidence="5">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="156" mass="17645" checksum="658DA3997D49C02E" modified="2021-09-29" version="1">MTEIIIIAAVAKNRVIGKDQSLPWSLPEDLKYFKETTRGNAVIMGRRTFESIGGGKALPERLNIILSRSMHEIDGSYVSRSLDEAVQLCEDKGYNKIFIIGGSSVYAEALGRATKMILSEIPEDYEGNVFFPEFGEEWKEVSRDKREGFDIVTYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQ63</accession>
    <name>A0A832UQ63_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="83" mass="9265" checksum="F71C6910033CA3CB" modified="2021-09-29" version="1">MEESVKMSEPTMFVEVEVKCKNCDHLDKVHVPVVCGVDKTSSDKTLYCDLEGDLKDYAPDCKECGKKDYEVEKEPVFIGEGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQ74</accession>
    <name>A0A832UQ74_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyhypusine synthase</fullName>
            <ecNumber evidence="2">2.5.1.46</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.46" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008612">
        <property type="term" value="P:peptidyl-lysine modification to peptidyl-hypusine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="PTHR11703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="323" mass="36503" checksum="799AE288C7998705" modified="2021-09-29" version="1">MAKEYTDSKPVKDIILEANEGADSIVRQMFESGGFVAKKLAVGVNILEKMNRDEGCVKFFSSPSAPVATGCRGIYRDLIKNQLVDVFITTSGMVDHDYARVWRDYYHGDFEMDDSELYKKGINREGNVLIPNECYGEILEDRIQPLLEKLYAEKTEYSTKELCWALGESLKDEDNKESSILYWAWKKQIPIYIPGPTDGAFGSQMWLFSQKKPDFKIDLFKDGHELNSIVMDAKTTGAFMIGGGISKHHTIWWNQFRGGLDYAVYITTAPEWDGSLSGARIKEAISWGKVKEKADHIDIEGDATTMLPLMISSLMERLGTSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQ89</accession>
    <name>A0A832UQ89_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="391" mass="42532" checksum="802CFC3B553CE033" modified="2021-09-29" version="1">MRLGKLLTIGLILFFILVSSVQAIGITPARVTVDFEPGMEGVKNFCVINNQKKSMGVELFVNGGLAEYIELSATRATMNPAEYSKCFSYIYSLPDRLEPGTHEARIGVIEIPPVSVFEGTGISTRASVLSQFRVFVPPEGSHIQIERILTSQAEVGYQVTIKLLVRSIGTEDTEFYGDVKISDSNNINLGTLTVPKTLVTAGAVKIVELKWGGSTIPGRYSILASLTYDEGVETTGTVEIKIGGEHVDIIAEDSMQVALDDISKFILTVENFWSEEIEDVSGRIVIQDSTGKIIEQLSIDSFDLKALGTKNLNLFWDSRDASAGEYLVTVVLDYLDGKVSTKKITLSIGAVSAVSEKISVDAPSQELVATLSLLLIILVILTIIYVVVRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UT81</accession>
    <name>A0A832UT81_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000005">
        <property type="protein sequence ID" value="HIJ99349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="63" mass="6631" checksum="EB3FA5242421652E" modified="2021-09-29" version="1">MASYILIIMSVIDIAAGFLLAAVPQSQVFLASFSVSPVLATYLAGILLVKGAYSLFHGVIRSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTS7</accession>
    <name>A0A832UTS7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_02155</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Part of a potassium transport system.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="136"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="219" mass="23215" checksum="4F734DE588D01218" modified="2021-09-29" version="1">MYIIIAGGGNSGEALAKTLVKEKEDVVLIESDKDKAEKLSEELDALIICGDSTNIDILKDAGISKADAVVAMTGDDKANLMICEIANQANVKRVLARINEPENEALFIQAGVESAISSTNSIVTDFKNVLRGKSSKTVATLAAGAIELIEIYIGDNSKIVGKTVSNVGIDKNVAKISSIERSGEIIIADDTRIINKGDILGVIAKSSSAKKIVEHFEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTT9</accession>
    <name>A0A832UTT9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF63 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002749">
        <property type="entry name" value="DUF63"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40700">
        <property type="entry name" value="PTHR40700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01889">
        <property type="entry name" value="DUF63"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="267" mass="29788" checksum="52BA31F6B7B6016A" modified="2021-09-29" version="1">MGITEFVQSYYINPLTVNPDGPYNIYNTITYGILLAVAVYYLYGFLNKLKMKFDGRFFVATIPFIALAAVLRVLRDGNIIESVWLVSPLIYVSVFLMTVIPLVGSFLIERKIPRLKYHVVTFTLGVGLIFIFGSLLSVVNVAGAAKIFGLGLASSGAIFFASTLVKNDFFSKINLGILYAAMFDAASTYIGVAQYGYFEKHVLPNLLFEMFGPWAMFPLKLLVLGAILYILDKYEEDLNFNNFIKFAILVLTLAPAFRNTLRLLVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTU9</accession>
    <name>A0A832UTU9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpl13</name>
        <name evidence="4" type="ORF">H1011_02315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005755">
        <property type="entry name" value="Ribosomal_L13_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545:SF3">
        <property type="entry name" value="PTHR11545:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01077">
        <property type="entry name" value="L13_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="141" mass="16095" checksum="9A20F942120BBE8E" modified="2021-09-29" version="1">MTIIDGTNLRLGRLASSVAKRALRGEEIIILNTEKCVITGKKRSVIKDKRDMRQIGSRYKGPFLPKRADRIVKRAIRGMLPYKKKRGREAMGRIRTYIGIPEEFKDQVKDLETLENAELGAVMKKNYITVETLSKEAGYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UU86</accession>
    <name>A0A832UU86_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S27ae</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rps27ae</name>
        <name evidence="9" type="ORF">H1011_03290</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eukaryotic ribosomal protein eS31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00777">
        <property type="entry name" value="Ribosomal_S27ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002906">
        <property type="entry name" value="Ribosomal_S27a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022845">
        <property type="entry name" value="Ribosomal_S27ae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01599">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01402">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Ribosomal_S27" evidence="8">
        <location>
            <begin position="7"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="47"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="54"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="92" mass="10317" checksum="FD6B3B6653BD8C0D" modified="2021-09-29" version="1">MPQKRNKHELYDTSEGISRKNRICPRCGPGIFLAKHADREACGACGYTEFPNNPKEDESPKEKAPEAIEGEEEKAPDKKEEQPAEEAKESSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UUD1</accession>
    <name>A0A832UUD1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="55"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="238" mass="26704" checksum="9CCD4519B4917784" modified="2021-09-29" version="1">MSKLKDSIGFGEYSTRGDYHRSPNKKWLYYPIFMEKQNYVKKLCKNLNTEGSKFLDVGCGEGVLVDELSKSGIDISGLDLNYKSKLVKRGSILDMPFKANSLDVVLCLDVLEHIDYNGQKKALSEIKRVLKKGGTAIISLPNIGHIAGRFVFLLGGFSRTAAPERHIGERTYKEWKTLIGEELSVNHSKGLFPTFPLISLYTLASPKASLWLHRLENTVFGGWLQSFCFLSVFTASKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UUD9</accession>
    <name>A0A832UUD9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zn-ribbon domain-containing OB-fold protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002878">
        <property type="entry name" value="DUF35_OB-fold_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022002">
        <property type="entry name" value="DUF35_Znr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12172">
        <property type="entry name" value="DUF35_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01796">
        <property type="entry name" value="OB_aCoA_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF35_N" evidence="2">
        <location>
            <begin position="8"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="OB_aCoA_assoc" evidence="1">
        <location>
            <begin position="47"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="130" mass="14554" checksum="B95FAAF006D09687" modified="2021-09-29" version="1">MSVSRFWREIPSRYNLSGGKCTGCNLINFPRRERCKDCGVSDFETIKLSGLGKILTYTKIHAAAEAFEHETPYYLAIIELEEGPRLTAQIVDAHKGEVSIGAEVESCFRKISEDGKAGAISYGYKFKPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UY17</accession>
    <name>A0A832UY17_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000006">
        <property type="protein sequence ID" value="HIJ99358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="125" mass="13338" checksum="0D3391ABD5DE7DF2" modified="2021-09-29" version="1">GISISIGIVITIVMLVVAFGMVVNILITGKEAPQSQIEETVGQTGRAVDSIDISKKFERFETECVADNEDPTCTSIGSRSLCEDLGCDWSNFKCTGGTVTCSDLDSVNCIKVSGCSWKMGETSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UY40</accession>
    <name>A0A832UY40_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H-hydrate epimerase</fullName>
            <ecNumber evidence="2">5.1.99.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.6" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="1">
        <location>
            <begin position="172"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="362" mass="39291" checksum="8070EBAC7B5B5728" modified="2021-09-29" version="1">MKRKMKIDVEAIWDAVEMPKPLRTHCKTVKKSCDKVVKALEARGIYPDKEIVNYGALLHDVGRVIDGGVRQGFEGYKILLELGVPEEVALCARNHVGSGIPKEEAVVKGLPEEDFIPETLEQKIVAYGDNLVAFDKITSYAEFRAGFVEKFGEVSTQVAMSDLLHSEMADFITCDEMLNAEQASEIPVHQLMDNVGKGLAEILDKRFGVEGKKIVIYCGPGNNGGDGYSAALYLKEKGANIEVLSFGEPHSPESKEFKSLSLEKKTNIAVVLSSKDLENIKADIIIDCLLGTGSEGSVKDPIKSAISKINNSKAVIVSVDLPSGIGTKVHVKPDLTVAIHKIKRKMVGFGKVGDTIVLNIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYT0</accession>
    <name>A0A832UYT0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="275" mass="31685" checksum="0AB1C8DA2F0913C7" modified="2021-09-29" version="1">MNFEELTKDQEKLQKALSPLNKLKRDASKLANDRDSLNEIVKKSSSDVKKLKKERDKLNESVQRRKYEREALNKQREEAKKIQEKNPQTPAAPSTYAILKKRIKSLLWKIETSGVSFKEEKKMREEFDVLSKEAGTLETQVSATRVLKSSTREASKKHQDVVGLAQKSESVHKDLIKAYAELRKSRSSANKTHGKLMETREQIKNFEELNKEDIDKLEKITKGIKAEKKKAREIASIGGIKVLKKAEKVKKEFEAGKRVDLRDLQATIEIKKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYT9</accession>
    <name>A0A832UYT9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="208" mass="21413" checksum="926C27967D71789D" modified="2021-09-29" version="1">MVKQIESGTAAFVLTLVAIVSVLGTTAILTSSGPVPFITGFASGAYNTTATASVNVSDYVIMSLNSSVLKFGEDAPLTPGASDDTTDGTPDPLILTNDGNVEMNVSVQKNDDLFTTDVSGSLQIKVANVTAGDNAGCNHGGSGTLALTFTDIVSSPNPTQIIRNLGYVAANDTCAIHFKVTVPSDEPAGNYTSVLTFTGVKRGYLLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYU7</accession>
    <name>A0A832UYU7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Translation initiation factor IF-2 subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_03260</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01888">
        <property type="entry name" value="eIF2_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15490">
        <property type="entry name" value="eIF2_gamma_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015256">
        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044128">
        <property type="entry name" value="eIF2g_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022424">
        <property type="entry name" value="TIF2_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03680">
        <property type="entry name" value="eif2g_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="3"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="400" mass="43493" checksum="1C34308B4C806BA1" modified="2021-09-29" version="1">MSLPELTIGLVGHVDHGKTTLTKKLTGVWTDRHSEELKRGITIRLGYADATFYKCKDSKGNIFYTAQEKDKLCEGKATKVRSVSFVDAPGHETLMATMLSGASIMDGALLLVSANEDCPQPQTKEHLMALEIVGIKNIIIVQNKIDLVTEEKAIENYKQIKEFVKGTVAEKAPIIPVSAEHGTNLDVLIETIQDDIPNAEPRKDAKPLMYIARSFDINKPGSDPVKMKGGVIGGALVEGALKVGDDIDIGPKRDGTFIRTKIVKLTTGGDEVKSVGRGGTFGIETGLDPCLTKTDKMAGKIAGHTGTLTKSVKIVNMEVHLLDRAVGSEEELEIKPLSKHEPLMLNIGTSTNVGVVQSGKKKGQYEFKLKFPACVENGSRITIARRYGSRWRLIGYGIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYZ5</accession>
    <name>A0A832UYZ5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="87" mass="9109" checksum="C5BF9F5C5C5B4650" modified="2021-09-29" version="1">METKIILKTALIALVVFVAIISVAEARRGAADEDAQDCILKPVTGLSIASVTGGFSYIFAGGASPLIILAVAFIVGFISSHFIWHGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZI4</accession>
    <name>A0A832UZI4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="75" mass="8861" checksum="41E899B105418570" modified="2021-09-29" version="1">MIWGFEAIVYYLFVLDSSIYFVMAFSKGKLHNKVKHWYSKYAKYFFEFPLNRGVAILYLALVIWVGLSLSRLAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZK4</accession>
    <name>A0A832UZK4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="206" mass="23265" checksum="3941796A1894B6EF" modified="2021-09-29" version="1">MSLKILGSEKALIGKSGIPEKLVLPSQILKKIAKVSKKRLTFKKTGIEYLGVLRGRREGGVKILSKGGKPGSSQGGYFIVTDVEHVDEEYCFPYLVRTSHLSREESDMIGIAHSHIKHIVPGEFPNDDYFEKDFYSKPAKERLLSPSANDAQSARTFISEQNRENGMGAVILMVNKRKHIWSKLPLKAYFVRWNDEGMYPLKIELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZN5</accession>
    <name>A0A832UZN5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="10" type="ORF">H1011_00890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Part of the protein translocation apparatus. Forms a complex with SecD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_A">
        <property type="entry name" value="SecF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024921">
        <property type="entry name" value="SecF_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="190"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="261"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="287" mass="31162" checksum="9AB81EFDB6621208" modified="2021-09-29" version="1">MKISESTYKKLVVIPIILILASVSILFINYSNTGEFLVKGIDLEGGTQIIIHHSAPVDISDAELTIEKFLGADDVDVVTTTNPASRKQETVIISASGDIEGEDIVEAAEDYFGITLAPNTYSIKILGSSLAVTFWSQAKWAFTFAFIFMASVVFIYFRTPYPSFTVVLAIFCDILVILGFMSLFGIKLSLATIAALLMILGYGVDSNILLANKILKESGGLVIDRIYDAMKTGLVMSASTISAMLALVILSNSIVLQQIGLVLLIGLIADLLNTWILNGNLLLWHQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZQ6</accession>
    <name>A0A832UZQ6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Serine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Seryl-tRNA synthetase</fullName>
            <shortName evidence="6">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">serS</name>
        <name evidence="8" type="ORF">H1011_01050</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11778">
        <property type="entry name" value="PTHR11778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="7">
        <location>
            <begin position="138"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="6">
        <location>
            <begin position="229"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="260"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="347"/>
            <end position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="423" mass="48024" checksum="302075FB916EFDB7" modified="2021-09-29" version="1">MIDISLLRDNPELFKDDLRKRKEPQNIVDDVLKLDKEWRNLLTDRDNLKAERNKVNLDIAKLKQAKKPATTEIKAMQAIASKIKKADEKTEKKLAERDELLCTLPNLMHDSVPPGEDDKDNVIIKTVGKKPAIKKPLDHIDLGLKHDLFDTERAAKTSGARFYFLKNEGAELEMALAQYAMKVMIKEGFTPMIPPVLVREEVMYGVGMLPKSRNEIFKIENEDLYLALTAEHSLGGYLMNETFEKTELPIRLAGLSSCFRTEAGSHGRDTKGIFRVHQFQKVEMFSFTEPEKSWDEHEKLLAVAEKLVKDLEIPYRVVNICTGDLGNVASKKYDIEAWLPGQGKYREIISCSNCTDYQARRLNIKYRPQAGERGIPLHTLNSTALALGRTIVAILENHQQADGTIKVPKVLHPYMSTKVIGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZR5</accession>
    <name>A0A832UZR5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="23"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="156" mass="17679" checksum="A8F40A8A853971B2" modified="2021-09-29" version="1">MGVRALLSGIFKKIKGRFSDEDDLEDELGSDEDLEDDLPEDEEDDEDDLDDLNEKPEPSPTPPPSTKPPVSESPLTPSPQAQKVSSVPHDSEKISTELATIRTKIDLLESHLQNIESKEALYKSEADRYMQYLTYISDKLDNLAREHAELERLIRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZS6</accession>
    <name>A0A832UZS6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpl14</name>
        <name evidence="5" type="ORF">H1011_02640</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="131" mass="13972" checksum="5D4CD37A73687009" modified="2021-09-29" version="1">MKTKGDITKSLPVGAVLVCADNSGAKKLQIIAVKNMKTRKRQIMSAGVSDIAMCSVVAGNPDMKKTVVPAVIVRQRKEYLRADGTRIKFSDNAAVVMTPEGTMKATEIRGPVAREAVQKWSSIGSAAKVVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZS9</accession>
    <name>A0A832UZS9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_01280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04476">
        <property type="entry name" value="RPA1_DBD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="OB" evidence="3">
        <location>
            <begin position="75"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="OB" evidence="3">
        <location>
            <begin position="194"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="Rep_fac-A_C" evidence="4">
        <location>
            <begin position="320"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="455" mass="49637" checksum="A7EBAC1C29949FDF" modified="2021-09-29" version="1">MGELEELIHTVSEKTGLGEDEIKKKVKEKQRELSGLVSETGAAYIVANELGVKTKNRVIESTVRIGDILPEMRAVSVLGRIKAISPTREFVNKTGVKGKVANLEIVDNTESIRVAIWNQSDIDKLESGEIKEGQIIQVKNGYVREGYRGGLEISIGNKGKLIENPEDVNESEFPSEDEFTSAVEIGKIVPDSSVNIVGRVIRNFGVNEFERDGRAGKVANLVIGDKSGTVKLVLWNEKAEESVELGVGDLVRVGNGFVKQGQEGLEVQANWGTTLVKNPEGVEVPDADDIIYEGRGSSNNGAPRENVEVKISELKEGDKYRQVRGAIINVFGENFVHLMCPECNKKIREGQCEKCGIIEKPNKLLIINGTIDDGSGTISVSFFREAAEKLIGISSDEINSASVDIAAKVNEALGKEIVIEGSVKRNDYMDRLELNAYDVKPVDAVQAAEKMIGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZV2</accession>
    <name>A0A832UZV2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-ketoacid dehydrogenase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="325" mass="35573" checksum="F6A2B1EC4387F28D" modified="2021-09-29" version="1">MTEMHMVQALNSALDNLMKEDDSVIVLGEDVGVDGGVFRVTDGLLDKYGEKRVFDTPLAEAGIVGTSIGLAIKGFKPVAEMQFMGFVLPAMQQIISHAARMRNRSRGRYTCPLVVRMPCQGGVKALEHHSESTEVFFAHTPGLKVIMPSTPYDAKGLLISAIKDPDPVIFLEPKKLYRSIKQEVPEEAYEIPIGKASVLVEGDDITMISWGSMMRSTISAAEKLAKEGVNPEVIDLRTISPLDHDTIIESVKKTGRCIIVHEAARTGGMGAEIMARINERAFYSLEAPMKRVTGYDIVIPLPMGEDCYFPDAKRVYSGAKEVLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZV9</accession>
    <name>A0A832UZV9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribose-5-phosphate isomerase A</fullName>
            <ecNumber evidence="2">5.3.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Phosphoriboisomerase A</fullName>
            <shortName evidence="2">PRI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">rpiA</name>
        <name evidence="3" type="ORF">H1011_01590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>aldehydo-D-ribose 5-phosphate = D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14657"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="EC" id="5.3.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose 5-phosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009052">
        <property type="term" value="P:pentose-phosphate shunt, non-oxidative branch"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01398">
        <property type="entry name" value="RPI_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00170">
        <property type="entry name" value="Rib_5P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020672">
        <property type="entry name" value="Ribose5P_isomerase_typA_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004788">
        <property type="entry name" value="Ribose5P_isomerase_type_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11934">
        <property type="entry name" value="PTHR11934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06026">
        <property type="entry name" value="Rib_5-P_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00021">
        <property type="entry name" value="rpiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="28"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="80"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="93"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="217" mass="23519" checksum="B7ECA2E2AA857AE4" modified="2021-09-29" version="1">MDSEEKKKLVAEEASKIAEDGQIVGLGTGSTASYFIKALAARNLDITCVSSSKRSSELAESLGIKTLEPDNVEKIDLYVDGADEVSKDLDLIKGGGGAHTLEKNLAYRAERFIVIVDDSKLTHLLGDFPLPVEVREESLDESKKALEALGAKVTLRENFKTDLGNSILDCKFSAIIKPAELERIINNIDGVIDNGIFSKEKVSEVLVGTDEGIRHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V008</accession>
    <name>A0A832V008_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001593">
        <property type="entry name" value="Ribosomal_S3Ae"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01015">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01397">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="192" mass="21961" checksum="B0A0B91D653AA8F6" modified="2021-09-29" version="1">MAAPRTVDKWKSKKWYSVIAPDLFKNVVLCDTVAENPRLIPGRIVETNLSEVVAGYDSRRPTTKLRFRIKDVQGEKASTVFLGHRLHNEFERGLVRKNSSKVYSNDVFSTNDGKKIRLKGVLVTPSPINQSMKHDMRTKYLEIVKKEASSKNLNDFIHFILSGKLSGKLRSELKSIYSLKHALIKKTEIIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V009</accession>
    <name>A0A832V009_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gamma-glutamyl-gamma-aminobutyrate hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="191" mass="21467" checksum="F6734F285ECBFEA3" modified="2021-09-29" version="1">MLLLIDNGSKHTPELIAYFKKRKIKYIIAHPDSSLKSLMEHKFKGVIMSGGPLLYDEAVDIEEVDIDLAVLLDLNVPTLGICFGHQTIAEAFDGRMKKLPAKVEKNETIVIVKSNKLFKGVPKEFQAQEFHTDCVSELPYNFDLVARSDSCGVESMKHKSKEIYGVQFHPEASGEIGEQILDNFIKICDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V032</accession>
    <name>A0A832V032_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="9"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="210"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="496"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="597"/>
            <end position="638"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="816" mass="93031" checksum="45F5B212A4C99E9C" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V043</accession>
    <name>A0A832V043_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="114" mass="12538" checksum="46FAD9C453372F22" modified="2021-09-29" version="1">MKKRSILLIILLIIFISGCLTYSKSEKVKFLGEGDEISLTGYIFSEGSKFCFDSEATDCFPAFSNILSEDMFSTADCIVVVGVDATMSVSDGEKTLFLNSVSVIDEISFCKERT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V051</accession>
    <name>A0A832V051_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cob(I)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00561">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="200" mass="22298" checksum="94F0154D6FD82959" modified="2021-09-29" version="1">MRLGDTPNSRTGLGLVHVYTGDGKGKTTAALGLAMRAIGHGIKVYMIQFLKGGTYVGEYLASESFMPNFTIKQFGKKCTYSDMYKQDRDYSCGSCRDCFMTSSEMISSSKEALELSKEITSSGDYGLVILDEINIALSFKYIKIEDVLEMITNKSESTELVLTGRGAPEEIREVADYVTVLQREKHPFDRGIMGRWGVEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V080</accession>
    <name>A0A832V080_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF167 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0235 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="SSF69786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="95" mass="10738" checksum="03392392C619B233" modified="2021-09-29" version="1">MRFTVKVKPQSPAKRAQVAGSHELTVWVQSEAKDGKANKELLSFLTKSIRKSTGRKSSIHIISGGISKIKVLESDSTWEEIRKTFSHKNDRENEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V082</accession>
    <name>A0A832V082_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000019">
        <property type="protein sequence ID" value="HIJ99907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="201" mass="21578" checksum="D674F2673027AEE6" modified="2021-09-29" version="1" fragment="single">MKSKLLLTILIISLAVSISGCADIVDKFPLPTEEAEVTSAGFGKSLTYGIIIRDFSPSQSSVDSGDEVELGLDIENVGAHDAENIEVNLFQKSGFSIVSENSVSATSLLAPDLEFEQPGERLYSYWVMTAPSVSVNQQKSLKARISYDYSSLATSNIHLVSRDIYNEQGPGAFSIQSTTSSAPVSFAIYDVPPIKVSSSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V090</accession>
    <name>A0A832V090_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="302" mass="33391" checksum="A47BEFE0D0AE3615" modified="2021-09-29" version="1">MALRIFKKKVQEHYIEEGGPGLEGLKAEKNIQELTLEEEIFNGLKNEFVEVDGEESLKQSTSPRDPPILVIRTDYNPMSVWHRLPIRGDSGARHIPDFVLYSGSHKVPPAGKSPELIIECRQMPEEASNRIDARAVGDLVAKTVDLLPSNAILVTNRDLADYAKSFASQYGIALMTNDLDLSGKVSKIVNAHDKKVQDKLREHVEKAGKRLGNMESSRAPRKTPEESAKAEANLGQQISDSLGAQASMNADDISSVLKIPSSVIVNELYKLERTGKVGRVANKNGNEESNVIKQEWALRKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0E3</accession>
    <name>A0A832V0E3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dockerin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000272">
        <property type="term" value="P:polysaccharide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002105">
        <property type="entry name" value="Dockerin_1_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016134">
        <property type="entry name" value="Dockerin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036439">
        <property type="entry name" value="Dockerin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00404">
        <property type="entry name" value="Dockerin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63446">
        <property type="entry name" value="SSF63446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51766">
        <property type="entry name" value="DOCKERIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dockerin" evidence="1">
        <location>
            <begin position="814"/>
            <end position="883"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="906" mass="97014" checksum="C887F36FA20A84B9" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0F4</accession>
    <name>A0A832V0F4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">asnS</name>
        <name evidence="7" type="ORF">H1011_03180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="6">
        <location>
            <begin position="131"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="429" mass="49257" checksum="CBF2D7FC88BD4B60" modified="2021-09-29" version="1">MKKSIAIKEALSEKNVGKTVSIRGWVHRERGSNKFKFFVIRDVSGTIQAIVKSEDKKLFKIAEDATRESSVIVSGKIRKDKRAPTGYELQVTDLEIVGKAETFPISRDKSEEFLLDVRHLWVRSRKLTNVFKIRSTVVGAIHEYFRKNEFIETQVPILTPTACEGGSSLFKVDYFGDTVYLTQSWQLYSEALAASLEKLYTIAPSFRAEKSRTPRHLTEYWHAEMEVIYCDLPQLMKYGEELVSYVCQEVARKNTDELKELGQDPRELKKIKAPFPKITYKEALDILAKNGMKVKYGKDLRTLEERELMKHFERPVFVTNYPKEIMAFYKPEDPENPGTALCFDLIVPEVGELIGGSVRDLDVDAMKKVLTDEGEDLSTYEWYFDTRKYGAVPHAGFGLGVERLVMWICGLEHIRDAIPFPRTINRKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0G5</accession>
    <name>A0A832V0G5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 15" type="primary">rpe</name>
        <name evidence="15" type="ORF">H1011_03295</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="171"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="193"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="HIJ99815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="216" mass="23190" checksum="C45F70C82200B4E8" modified="2021-09-29" version="1">MKIAPSILSADFANLGKDIGMVEQHTDLLHIDVMDGHFVPNISIGIPVVESIRKFTEMRLDAHLMIENPEKYIEAFALAGADTIIVHAETIKDGKPLQDIKDHNKRAGVSINPETPVSEIESYLGGVGQVLVMSVNPGFGGQSFMPEALPKIEELKKLRKENDFQFEIAVDGGVNTETSPKIVEAGADILIAGSAIFGSDDPLGAIIKMKGDGDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0H2</accession>
    <name>A0A832V0H2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translation initiation factor IF-2 subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_03375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-beta/eIF-5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045196">
        <property type="entry name" value="IF2/IF5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002735">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016189">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016190">
        <property type="entry name" value="Transl_init_fac_IF2/IF5_Zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23001">
        <property type="entry name" value="PTHR23001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01873">
        <property type="entry name" value="eIF-5_eIF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00653">
        <property type="entry name" value="eIF2B_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100966">
        <property type="entry name" value="SSF100966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75689">
        <property type="entry name" value="SSF75689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eIF2B_5" evidence="4">
        <location>
            <begin position="22"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="135" mass="15104" checksum="EA350F8B9FD4EA45" modified="2021-09-29" version="1">MKSYEELLKKAKEQLPEVASEKARFEIPVFESFIQGSETIISNFVEVANKVERDPAHLQKFILSEAGTSGTLSGQRLTFKGNKTPKFLNLKLSDYYKAFVACKQCDLPDTILNEGDDSAELKCKACGTNYMVKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0J8</accession>
    <name>A0A832V0J8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lon proteolytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_03620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="591"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="3">
        <location>
            <begin position="26"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="258"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="623" mass="68585" checksum="3E7C8186A057B2B0" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0K8</accession>
    <name>A0A832V0K8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thiolase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiolase_N" evidence="1">
        <location>
            <begin position="5"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="2">
        <location>
            <begin position="261"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="386" mass="40449" checksum="D5D4BDAE3884C220" modified="2021-09-29" version="1">MNQEVAIIGIGMTKFGELWNRSFRQLFVEAGSEALEDAGIKSEEIGALFGGNMSAGQFIGQEHLASLIMDHSNMTPQPATRVEAACASGGLALRTAYMSIKSGMHDVVIAAGAEKMTDVLPSKTTGALATAADQEWEAGFGATFPGLYAMIARRHMHEFGTTEEQLASVSVKNHYNGSKNPKAQFQNEITIDDVLSSPMVADPLKLFDCSPVSDGAAALVLASAEKAKELCENPVWIAGSGQASDTLALHSRKSLTTLNATVEAGRQAYKQAGITSKDIGAAEVHDCFTIAELCAIEDLGFCEKGDGGKFTEQGETGLKGSIPVNTSGGLKTKGHPVGATGIAQAIEASLQLRGEAGDRQIDDLEYVLTHNVGGSGGTAAVHIFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0U7</accession>
    <name>A0A832V0U7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S6e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps6e</name>
        <name evidence="6" type="ORF">H1011_03255</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00512">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001377">
        <property type="entry name" value="Ribosomal_S6e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020924">
        <property type="entry name" value="Ribosomal_S6e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018282">
        <property type="entry name" value="Ribosomal_S6e_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11502">
        <property type="entry name" value="PTHR11502"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01092">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01405">
        <property type="entry name" value="Ribosomal_S6e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00578">
        <property type="entry name" value="RIBOSOMAL_S6E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="118"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="126"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="177" mass="19126" checksum="B5E65E1EF928F11B" modified="2021-09-29" version="1">MKVVIGNARTGKTYSVETDVSNFTGKKVGDAVKGEILNLTGYELEITGGSDASGTPMRRDVSGATSRKLLLSKSTGFRGKRKGERRKKRIHGNIVSGNIVQLNTKVVKEGKEALDKLLAPAAEEAPSEKGADEVKVEEKPEKESPEEKKEEAPAKEKAEEVAEEKTEEDSDKKAVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0V3</accession>
    <name>A0A832V0V3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032751">
        <property type="entry name" value="Fuseless"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15993">
        <property type="entry name" value="Fuseless"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="71" mass="8415" checksum="F3DA147468963078" modified="2021-09-29" version="1">MVHRKFWKLQRHHRALFGSLIIIAIIGVWRGLWGLMDKYIFPEQYLLSHVTTLVGGFFVLWMTQNTIKSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1D6</accession>
    <name>A0A832V1D6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="599" mass="65874" checksum="F084FCA3D0133461" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1F7</accession>
    <name>A0A832V1F7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-sulfur cluster assembly factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="8"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="98" mass="10911" checksum="94846D9F9FE16118" modified="2021-09-29" version="1">MNQELTKERAIELLKECKDPELGLDVWTLGLIYELDVSASSVKIKMTLTSPTCPFGQMMISEIKDRLKLSGGASDVEVELTFTPPWEPPAKVRTMLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1I4</accession>
    <name>A0A832V1I4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_00670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01896">
        <property type="entry name" value="DRG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031662">
        <property type="entry name" value="GTP-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="PTHR43127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16897">
        <property type="entry name" value="MMR_HSR1_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="2">
        <location>
            <begin position="61"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="3">
        <location>
            <begin position="280"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="357" mass="39158" checksum="524B9C225F778BEB" modified="2021-09-29" version="1">MSVEDKIKEIEDEIRKTSYNKATEHHIGKLKAKLSKLRASAEKGSSQGVGLAYGIKKSGDATIIFAGFPSVGKSTLLNALTNAKSEVGHYDFTTLTVVPGAMKYKSAELQLLDVPGLIAGAASGKGRGREVLSVIRMGDLLCLVIDANKPGQYKQMLKELYDANLRIDERPPRISIEKRAYGGIQIEKISKCKLTNSLIKSVLSEFGYLNASITIQDAVDLDQLIDGIVKNRVYLPSLVIVNKSDSVKKIPKLHKEQVSISAKEGEGLDILKESIFTKLKLIRIFMKPQGEKADLEEPLLVTDGSTVGEVCSKLHKTFRKNFRYAMVTGKSAKFANQKAGLNHVLKDGDVLTIVQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1K6</accession>
    <name>A0A832V1K6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000005">
        <property type="protein sequence ID" value="HIJ99351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="97" mass="10883" checksum="2EFC63639E0BCEF2" modified="2021-09-29" version="1">MVYYYAPHWYTIHWSLAVAPLFIIFFGVLYLLGRKYFGGDKKVNMLIAAMAASGAYYAVGAQTNIYRFLLFNGNMIADLAVVAAIIAGVYYLLRIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1X2</accession>
    <name>A0A832V1X2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acetyl sugar amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020022">
        <property type="entry name" value="N-acetyl_sugar_amidoTrfase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03573">
        <property type="entry name" value="WbuX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="409" mass="48252" checksum="B0FF03CB2F52F60F" modified="2021-09-29" version="1">MSENLEAYFGLPNEVKFCTRCVISNQRPNSSIEFKHTKESKKKTINFDSEGVCDACRHAENKYNKIDWEKREEELYTLLDKYRKTDGSYDILVPGSGGKDSVYASHILKYKYDMHPLTITWAPHLYTNYGWENFQGWIHKGGLDNMLFTPNGKIHRLLTRQAFKNLLHPFQPFIFGQKNLAPKIAEKFDIPLVFYGENEAEYGNPIHDTSTAERDWKYFASNDLESTYLGGTSIQDLIEKHGVTMNDLDIYMPADPKMVEKKQIKVHYLGYYLKWIPQDNYYYSVEHTGFKPNDQRTEGTYSKYNSIDDKTDPYHYWTTLVKFGIGRTTYDAAQEIRNNHINRDEGVALVKRFDQEFPKRYFTEFLDYISMTEEEFWKTSDKFRSPHLWKKENGDWKLRHTVWKGGTDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1Z5</accession>
    <name>A0A832V1Z5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-directed RNA polymerase subunit Rpo5</fullName>
            <ecNumber evidence="2">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">DNA-directed RNA polymerase subunit H</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpo5</name>
        <name evidence="2" type="synonym">rpoH</name>
        <name evidence="4" type="ORF">H1011_01905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the RNA polymerase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.940.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00025">
        <property type="entry name" value="RNApol_Rpo5_RPB5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014381">
        <property type="entry name" value="Arch_Rpo5/euc_Rpb5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000783">
        <property type="entry name" value="RNA_pol_subH/Rpb5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035913">
        <property type="entry name" value="RPB5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10535">
        <property type="entry name" value="PTHR10535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01191">
        <property type="entry name" value="RNA_pol_Rpb5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55287">
        <property type="entry name" value="SSF55287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2 4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb5_C" evidence="3">
        <location>
            <begin position="8"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="81" mass="9213" checksum="C79074D598C8A8C7" modified="2021-09-29" version="1">MAEEKETFDVSAHSLVPKHEIMEEKDVEIILAKYGAERRQLPKISKNDPAIKGLKASKSQVIRITRKSETAGKTIYYRVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2B5</accession>
    <name>A0A832V2B5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyruvate dehydrogenase (Acetyl-transferring) E1 component subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdhA</name>
        <name evidence="3" type="ORF">H1011_02790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017596">
        <property type="entry name" value="PdhA/BkdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11516:SF41">
        <property type="entry name" value="PTHR11516:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03181">
        <property type="entry name" value="PDH_E1_alph_x"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="2">
        <location>
            <begin position="47"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="366" mass="41686" checksum="AEE96226435455C0" modified="2021-09-29" version="1">MAKKKDLFEEFNPLEGKVYQILDKDGKVVGDEPKLSEEQLKDMYFYMLYTRVSDEKAVNMQRQGRMLTYAPVSGQEALHVGSALALEKDDWVVPAFRENGVFLVKGLDLHKIYLYWKGNEEGALIPEGMNILPVTIPVASQTLHGVGIGWAQALKGEKAATVTYFGDGATSEGEFHEAMNFAAVFKANIVFICNNNQYAISVPVEKQTASKTLAQKAIAYEMPGIKVDGNDVLAMYSITKYALERARSGKGPSMIEGYTYRIGYHTTADDPTKYRDQKEVDEWRTKDPIIRFREYLKGKKIWTEKYEEEVQKKVKEMVSNEVKIAESFSKPPIKAYFEHTYAEMYPYLKEQLKEMSACEEEKEAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3M3</accession>
    <name>A0A832V3M3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Potassium channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0407">Ion channel</keyword>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK C-terminal" evidence="1">
        <location>
            <begin position="117"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="202" mass="22729" checksum="13CB7160E1A530E2" modified="2021-09-29" version="1">MADETYEVSEIVDELLTKKRGIKEIIKEMKNVSELMVDLAYSAILFNNNDLAEEVKGLEEEMNKLRLQIEISAMLAARTSEDASKLSGIIRVAAAAESISNAAERIADTVLRDIELHPVLKEALEEAEETVERIIVTAKSGIDGMAIKDIRDNEKYAVDILCIKRGGKWIFDPKWDVKLKTEDMVIVTGFKENVEQFKDLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3N9</accession>
    <name>A0A832V3N9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II/IV secretion system ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000005">
        <property type="protein sequence ID" value="HIJ99354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="1">
        <location>
            <begin position="364"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="764" mass="86457" checksum="D2FEA8BD7737346B" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3Q1</accession>
    <name>A0A832V3Q1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF5379 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="88" mass="9845" checksum="C75B99E531DDA0E1" modified="2021-09-29" version="1">MKFGIEQKTALIHVGLGAIVGFTSNLMGGGLTTILVAIIFLAVSAQLTSRLIPTLYPEVEYNKKWWLANALYPLVSFWLFTWVLLFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3R6</accession>
    <name>A0A832V3R6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="159" mass="17969" checksum="924E0F7ECB127C6A" modified="2021-09-29" version="1">MIAETKKDGRGRPVGSPIREKIKQILGALGCAYGYKIHKIYLLAFEPLEARQIYYHLKKGVQQDEFKEYGIEKIQGNYTWGSTSTRKYYSLDPTVVVEIPDSVFSAMRVLGLKYKETPEDSNKVVIKESDSSEKVSVDKDGGKNKVDDSDVSRPHKTYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3T8</accession>
    <name>A0A832V3T8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="104" mass="11429" checksum="C839751BB36E4E66" modified="2021-09-29" version="1">MGLLFNSAAIISSAITSVSLYLGATEIYAFILGAVLLYIPVKMLLPFGSKKPLSQTAIVASMCAVAYSSAGMTYASSFLFAVISAYVYIYWWLLIYPKFFLKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3W4</accession>
    <name>A0A832V3W4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="132" mass="14553" checksum="F3D0CC8E16EC73CA" modified="2021-09-29" version="1">MENDDRFDEWKPPEIKDGELTKWNWMVQNVEGLKLGKNTDIGAFTYINAKHGVEIQDKVQIGSHCSIYSESTIDEKSGKVTIEENARIGSHSLIMPGVTIGKNAVIGAFSFVTSDVPENSLAYGIPAKVVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V468</accession>
    <name>A0A832V468_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Endonuclease III</fullName>
            <ecNumber evidence="5">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DNA-(apurinic or apyrimidinic site) lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">nth</name>
        <name evidence="7" type="ORF">H1011_02885</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="5"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003906">
        <property type="term" value="F:DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00942">
        <property type="entry name" value="Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005759">
        <property type="entry name" value="Nth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01083">
        <property type="entry name" value="nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 5" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="6">
        <location>
            <begin position="47"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="222" mass="25168" checksum="8D72246E2C337368" modified="2021-09-29" version="1">MEVKKDSPQDIKKRALRVYKTLNKIHPVSRTALRHRNPFQLLVATILSAQCTDKQVNKVTPALFKKYRTVKEFVESDQTELESLVKSTGFYKSKARYIKGSSIKILSDFKGKVPKTMEELITLPGVARKTANIVLSSAFGINEGIAVDTHVKRVSYRLGLTEHKDPIKIEKDLVKLIPKADWDKFSLLLIYHGRDTCFARTPKCSECPFKKICPKTDVITSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V486</accession>
    <name>A0A832V486_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="18"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="108" mass="12437" checksum="70CEFFD670DAC184" modified="2021-09-29" version="1">MAGDSKKSEAKEKIPETEDHVLDALKDLQAQLEQLSEEKRKLENTVASVEGKIESTTQKEDDTRRQLAELVKHEDALRRTERALHKKLEMLKSESSRVLEIKSRLQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V4B8</accession>
    <name>A0A832V4B8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007504">
        <property type="entry name" value="H/ACA_rnp_Gar1/Naf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04410">
        <property type="entry name" value="Gar1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="75" mass="8151" checksum="35D41518D9E62565" modified="2021-09-29" version="1">MGLLGKVLHLSKNGNIIVSSSKLRNLPRTGVKAFDSDRILVGKVSEVFGPVSSPYVSVKPFNKDNESMIGKMVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V4C6</accession>
    <name>A0A832V4C6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="60" mass="5809" checksum="C187BC7B158960B7" modified="2021-09-29" version="1" fragment="single">MSSAAEDAKKRIRLGIKVTVIILVVGGLLFAVDKGFDIGIYSAIGSGIGSISTGGGGGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V7V8</accession>
    <name>A0A832V7V8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="194" mass="22024" checksum="891CB981995C30FE" modified="2021-09-29" version="1">MAEESESYEVVASSPYDELERKEEKLEHDINEIKSALRGTVGLTKIESHADEFIKKMMGLLESTQQMQMQVSKSNQQVAEKIQQALDLMNETNRGLSQKLSKILTIFAEATEAMETEEEGSMKEVSSAIGEMKSAMTDFKEQNKKLSKTLDSLERYLRRQSVAPQRAAMTLAPVQRQQQQQPRRQLPPPPLPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V884</accession>
    <name>A0A832V884_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="172" mass="20330" checksum="62BA7FC032133526" modified="2021-09-29" version="1">MAELLKVAGIEIKPLKKNEIEAQERVLSENSKIYKLILRYSAEEEREKAEETEVEVLDVISHVYNGLHEHDKIRSEVFKVASKGRGKKKEFYCYITPHTHVLKDAELEGLKNYHILRIFIEDGDVKIWLYLHKDQKKRDAREEDHFILILDIIKKRLWKEGIIFATEKNSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8B4</accession>
    <name>A0A832V8B4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000008">
        <property type="protein sequence ID" value="HIJ99490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="277" mass="32018" checksum="4155BE72C0E7DC66" modified="2021-09-29" version="1">MSIEIIAEGAHDVAHSVFESREILKKRPDAVFLELPSTPFQKILSAYSSGKLTDAQLKKNLLAAISAEKKEIDHDLVDKFIVGELEMEELESIETEGREFHVMKSAKKVGAELHAVDIPLDKLDPYLTKKVKEEHLEMAKVAFSTKRLPFIAWELADLFHYPFYFLERLVRNPSIKITNPFIHNINENKMAKLGAKYDRWVQRLVLPLFMHMPLSRELKDAIKVGYILGEMDVLRERFMAAKITKRYRELETELGREPNIIVIVHLWSSAELERLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8R1</accession>
    <name>A0A832V8R1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl15</name>
        <name evidence="8" type="ORF">H1011_02580</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027386">
        <property type="entry name" value="Rbsml_prot_L15/27a_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="7">
        <location>
            <begin position="28"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="110"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="151" mass="16238" checksum="D5DDB555294EEB7D" modified="2021-09-29" version="1">MSTTNKKIRKYRGRKTGGGAKKKRRGAGNRGGRGNAGRWDHKKMSARARDLTNKKLKSIKTRIPVINLSQVESMVIKDDLKEIDLSGYKVLGKGSLTKAISIKASSFSKSAAEKIKKIGGNAEGSVSGEEGTSEPDAIKEDVISENTSESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8U3</accession>
    <name>A0A832V8U3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thymidylate synthase</fullName>
            <ecNumber evidence="1">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">thyA</name>
        <name evidence="5" type="ORF">H1011_02810</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="4">
        <location>
            <begin position="2"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="280" mass="32341" checksum="4C7E78C9CF4722FB" modified="2021-09-29" version="1">MKEYLDLVKLVMDKGEYKHNERTGVGTISYFGASYKVDLSKKYPLLTTKKVNFNAVIYELLWYLSGEDHIRNLRKHTKIWDAWADDDGNLETAYGYFWRKFPSAQKDSAGNWQVKEIDQIQYVIDTLKNDPSSRRMVVTAWEPGNATVSKLPPCHYTYVFNVQKDRLNCHLTQRSADIALGVPFNIACYAALTKIMAQETGFKPGQFSHTLVDAHIYHAKPGSGMEEYDHLEGLKMQLERAPRELPTLEIAQKPINELKFEDFQLKDYNPHEPIRFKVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8Y0</accession>
    <name>A0A832V8Y0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="489"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="573" mass="61130" checksum="AA16B6D0E59C3B19" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V960</accession>
    <name>A0A832V960_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glyceraldehyde 3-phosphate phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_03725</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the dephosphorylation of D,L-glyceraldehyde 3-phosphate in vitro.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011950">
        <property type="entry name" value="HAD-SF_hydro_IA_CTE7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02253">
        <property type="entry name" value="CTE7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="216" mass="24638" checksum="62D2EAAF8E1C60C9" modified="2021-09-29" version="1">MKCIFFDLDGTLFDTRKLVEQSRRNSVAAMIEAGLPGTEEEVYDSLLKIVEKTGSNYDRHFNELLKERQVQMAGRIIAAGVISYHESKQKNIKTFDGIPEMLEELRKKYTLCVLTNGKLVKQWEKIIRLEIEKYFEFVFVSEEVGKRKPDHAIFLHALKNTGFKAEECIMVGDRDTDLVPAKELGMSTISVGDIEGADFSVTNPKDILDRVKQIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X4V6</accession>
    <name>A0A832X4V6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">ftsZ</name>
        <name evidence="9" type="ORF">H1011_00235</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5 6 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="34"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="8">
        <location>
            <begin position="227"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="42"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="129"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="366" mass="38872" checksum="C6CDF89847365E80" modified="2021-09-29" version="1">MDSTTENKAEGNGNVYTLSSDSGLEEVVQAKKTSIKVIGAGGAGNNTINRLMEVGIDGAECIAVNTDAQDLLYTEADQKVLIGKDVTGGLGAGSNPDLGMEAAKEDEKELKELIKGSDLVFVTCGLGGGTGTGSLPVLSELAKKEKALTIGIVTMPFSIEGAVRWDNAQAGLKQLREHTDTVIVIPNDKLLEIVPELPLNAAFKVADEILVNAVKGITELVTKEGLVNLDFADIRTIMSNGGTAMIGLGESDTDDRARDAVEKALSNPLLDVDITGATGALINVIGGPDMSLQDARIVMETVSDKLDPNAKIIWGSRIDPDFQNTLRTMLVITGLKPQQQILGPETSEEKKVYKSKMEKEYGIEFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5D3</accession>
    <name>A0A832X5D3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Glutamyl-tRNA(Gln) amidotransferase subunit E</fullName>
            <shortName evidence="6">Glu-ADT subunit E</shortName>
            <ecNumber evidence="6">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">gatE</name>
        <name evidence="8" type="ORF">H1011_02755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of GatD and GatE.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the GatB/GatE family. GatE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00588">
        <property type="entry name" value="GatE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004414">
        <property type="entry name" value="GatE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659:SF2">
        <property type="entry name" value="PTHR11659:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00134">
        <property type="entry name" value="gatE_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatB_Yqey" evidence="7">
        <location>
            <begin position="478"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="623" mass="69991" checksum="4AED4F9C8585ACBB" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5F3</accession>
    <name>A0A832X5F3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protease HtpX homolog</fullName>
            <ecNumber evidence="11">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">htpX</name>
        <name evidence="13" type="ORF">H1011_02990</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the peptidase M48B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="11"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00188">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022919">
        <property type="entry name" value="Pept_M48_protease_HtpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11 13" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 11 13" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="12">
        <location>
            <begin position="67"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="HIJ99764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="280" mass="30727" checksum="98EA4B4839548AEE" modified="2021-09-29" version="1">MPQTQNKMRTFILFSVLLGIFLAVGSLWGTFGMLTALIFALLLNFASYWYSDKVVLAIYRAKIVSKKESPRLYRVVEKLANKAKLPMPKVAIMKSSNPNAFATGRNKENATVCATTGILDLLDNNELEAVFAHELGHINNRDILVSTISATLAGAIMILGRLAWFMSLGRNSRQGGNALGFLLTMFLAPVAAMIVQLAISRDREYGADIFGASLTKKPKYLISALTKISSAGSRHPMRLGNQASAHMFILNPFRAQRLAGLFSTHPPLAERVKRLEGLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5K0</accession>
    <name>A0A832X5K0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps13</name>
        <name evidence="7" type="ORF">H1011_03585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="134"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="148" mass="16955" checksum="23BF7EC169BCBDEE" modified="2021-09-29" version="1">MAEKIKTIIRLLRKDVPGDLTIENALTRVNGIGFSVASAVRLKLDIPRSTRLSELSDEQLKELNLLLESTDELNLPEWMRNRRKDNETGTDVHLLDTNLMFANRDDLIKYKKLKNYRGLRHMFGLKVRGQRTRSTGRKGTSMGVSRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5K8</accession>
    <name>A0A832X5K8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032751">
        <property type="entry name" value="Fuseless"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15993">
        <property type="entry name" value="Fuseless"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="70" mass="8004" checksum="3590A2E871D7305F" modified="2021-09-29" version="1">MSVLLDRWRRRHIVLFSLIIGISTLSFAWGTWRLMDIYLFPTSPGTAAWSAILLGFFILSITGFVSKELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFJ1</accession>
    <name>A0A832XFJ1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NPCBM_assoc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018905">
        <property type="entry name" value="A-galactase_NEW3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10633">
        <property type="entry name" value="NPCBM_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1205"/>
            <end position="1226"/>
        </location>
    </feature>
    <feature type="domain" description="NPCBM_assoc" evidence="2">
        <location>
            <begin position="1001"/>
            <end position="1079"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="1316" mass="140487" checksum="F65385E449188050" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFS5</accession>
    <name>A0A832XFS5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="120" mass="13895" checksum="D5B3DB63795E66CF" modified="2021-09-29" version="1">MEKGVPESLRMWFLFHFAVDLAFGLPLLFQPEFLFKLFGLPFVELLTARLLGAGLLGLGFVSLYAHKKGREVYDTLLTMKIAWSLVAIFALLISRPILWPIVAIFVIFSATWIYYRRRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFW7</accession>
    <name>A0A832XFW7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="4">6.3.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">H1011_01990</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="108"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="432" mass="46855" checksum="00E0A62278E72CCC" modified="2021-09-29" version="1">MKSLLIGDGAREHAIAKRMVEGSELYAFVSLPNPGISSLASEIKVGNILDANEVILFARHVSPEYIFIGPGTVIAAGVGDALSEAGFQVVAPSRAGARLEWDPAFFRFFIQDHAPDASLKFAACESRHEVNNAFRDIGTSLSIITSESPENHFENPYLAREYAYRSIGAKSSGSSSVVLQEKAEGEDFTLQVFTDGETVSAMPLVKKYALSENEKTNLSEGVGTYSESNHLLPYISAEDAEKSLSILRKLLRALKSAHNSVYRGVLCARFVITLGGPKLLNISAGFGDPEALNVLSLLKTDFSHLCMSILGGKLWPSIEFKKKASVCKYLVPLGYPEKPKIGVPLSVDEDKISRAGAELYYNSVSIKDGKLYTSEGRSLALLSVADAHEDAEDFVESAISAVNSENLFYRKDIGTVGLSQKGVNRMEELRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG00</accession>
    <name>A0A832XG00_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="133" mass="14724" checksum="948C1674C0FDA9CE" modified="2021-09-29" version="1">MKMLLPQEIQANYVLPALRRELALALIDQRKLKQGDAAALLGVTSSAISQYRSAKRGGTLKFGDEILEEISISSKKLEKGTSEPLQELLRLLNLPRAFDIVCNIHKKDDPRAENACAGCHIAPENRSVEENND</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHA4</accession>
    <name>A0A832XHA4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hsp20/alpha crystallin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_00060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="87"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="197" mass="22869" checksum="40D499C4F374E6E4" modified="2021-09-29" version="1">MTKKMERKGDWWRKYTKRYIDEDVSQKKSVNRLKGLTKSKSQEFPYTEVSDPFREIQKISKGINQMFTDMLNRDFSKSPELPRTLKMQEGLFRQPIVQVKEGRKDLIVKVELPGLRKDDITLKVEGSHLIIDASVKSEKKREESGYIGFSSDYIGFRNVVRLPVLVDKNLSKATYKSGILTVILRKLPPDEGEIDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHC3</accession>
    <name>A0A832XHC3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_00410</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="9">
        <location>
            <begin position="183"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="7">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="423" mass="46309" checksum="DB237D035DEC9870" modified="2021-09-29" version="1">MDASLNPFENALKQLENAQNIEPIDEDIYQILRRPQRIIELSIPVKMDSGELKFFTGYRVQYNDAPGPTKGGIRYHPQVSLDEIMALASWMTWKCAVVGLPYGGAKGGVICNPKDMSEGEIERLSRAYVQAIANCIGPTVDIPAPDVYTNPQIMAWMSDEYNKIVGKELPAAFTGKPVENGGSEGRNISTGVGCSFIVREISKKLGLKPKETTVAVQGYGNAGSIVAQKLHEMDYKIVAVSDSQGGIYSEKGFDPHKILTCKSKVGTVGECGHIGVLAEGAEFQKITNEELLELEVDILIPAALENQITVENADKIKAKAVVELANGPTTPAADEILFKKGITVVPDILANAGGVSVSYYEWYQNMNNESWTEEDIFKKLDTLLTKAFVNISEKSDKNKIDMRTAAFILAVHKVAEKVKERGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHG5</accession>
    <name>A0A832XHG5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 13">V-type ATP synthase alpha chain</fullName>
            <ecNumber evidence="4 13">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">V-ATPase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpA</name>
        <name evidence="17" type="ORF">H1011_01180</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13">Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="4 13"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033178">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, catalytic domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00309">
        <property type="entry name" value="ATP_synth_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031686">
        <property type="entry name" value="ATP-synth_a_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005726">
        <property type="entry name" value="ATP_synth_asu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022878">
        <property type="entry name" value="V-ATPase_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43607">
        <property type="entry name" value="PTHR43607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16886">
        <property type="entry name" value="ATP-synt_ab_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01043">
        <property type="entry name" value="ATP_syn_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="6 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="15">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_Xtn" evidence="16">
        <location>
            <begin position="83"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="14">
        <location>
            <begin position="207"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="227"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF16886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="HIJ99420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="590" mass="65717" checksum="7620554FF8D91E5B" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHI5</accession>
    <name>A0A832XHI5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="73" mass="7817" checksum="F3FFC3E913FE1875" modified="2021-09-29" version="1">MAARDKLFGAALSLASLGLGTAYFYALFGPGGYALWAMSIAVSALVVLFLLIFAWAGWVIMTSPTVEELEEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHN1</accession>
    <name>A0A832XHN1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="152" mass="17154" checksum="ED62C2FC5A8D6C87" modified="2021-09-29" version="1">MGFKKFFVVIGIGLIFTIFFAYGMEVFYESPDYDCWDLLDKNETRDPYFNPKNDPTYRACEETYDIESEKHARVGFIALGSIAIVAIAAGILLTGLDAVGSGLLSGGIFLFIYTTLRYWGFLNKYLRLSLIGFALAALLYFGYTKIDKKAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHQ3</accession>
    <name>A0A832XHQ3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="78" mass="8997" checksum="D660288F9BF5B5D2" modified="2021-09-29" version="1">MEEEVMVGCKVCGQENCVESRKTEWACAKCGEETERLFFSYRCEKCESQKFNITRKLACKECGAESELSEEHDTTEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHS9</accession>
    <name>A0A832XHS9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Type 2 DNA topoisomerase 6 subunit B</fullName>
            <ecNumber evidence="1">5.6.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Type II DNA topoisomerase VI subunit B</fullName>
            <shortName evidence="1">TopoVI-B</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 4" type="primary">top6B</name>
        <name evidence="4" type="ORF">H1011_03350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Relaxes both positive and negative superturns and exhibits a strong decatenase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer. Heterotetramer of two Top6A and two Top6B chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TOP6B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00823">
        <property type="entry name" value="TopoIIB_Trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00322">
        <property type="entry name" value="Top6B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005734">
        <property type="entry name" value="TopoVI_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015320">
        <property type="entry name" value="TopoVI_B_transducer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF4">
        <property type="entry name" value="PTHR10871:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09239">
        <property type="entry name" value="Topo-VIb_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006553">
        <property type="entry name" value="TopoVI_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01052">
        <property type="entry name" value="top6b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="HATPase_c" evidence="3">
        <location>
            <begin position="34"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="516"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="520"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="102"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="112"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="439"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="550" mass="61607" checksum="7D76497D8677F144" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHT3</accession>
    <name>A0A832XHT3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="48" mass="5782" checksum="E5C785AA4F58C9C4" modified="2021-09-29" version="1">MNEEEKAKRYVKKLESEDEVDEHTEKLMIHDSLEDKKPKKANKPRIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIG9</accession>
    <name>A0A832XIG9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription elongation factor Spt5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">spt5</name>
        <name evidence="7" type="ORF">H1011_00245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Stimulates transcription elongation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Spt5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00950">
        <property type="entry name" value="Spt5_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005100">
        <property type="entry name" value="NGN-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011590">
        <property type="entry name" value="Spt5_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03439">
        <property type="entry name" value="Spt5-NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00405">
        <property type="entry name" value="KOW_elon_Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NGN" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="6">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="143"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="175" mass="19068" checksum="BEFAD03B6334AB62" modified="2021-09-29" version="1">MGIYAIRTTANKEKNVASKLADRVEKEGYNISSIIVSGLKSYILVEGDRADIDKAYRGVAHARGLVSGEAKLDEIQHFLKPKLAVTNLVEGYIVEVISGPFKGEKARITRIDTTKNEITIELLEATIAIPITVPAESVRVLEKVEPEVEEKETKGDIREGNSEESSSGGDFPVPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIK5</accession>
    <name>A0A832XIK5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="12"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="70"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="266" mass="30161" checksum="50EA87940CB7256F" modified="2021-09-29" version="1">MRSPNNKAEDFMTKNPETVSPDAVLEDILLKMKERRRDGLLVVKGKSLVGILFYVDTLLQSPKTKVNEIMEKKVVAVPPEMDMQGVARLMFRRGFSRLPVVDKQGKLLGLLRNYDVIRASIERVTPRKIETTKKMISAIHKVGMSIKREEIKIQTLIPTQPKVYLDELRAREYELQKGLAEPILIIRNGSREILVDGHHRVVAAGNLKIEKMKAYVITLDKEISLGLEKNAEKQGLKNPKDIEIVDGYSPYALPIVLENGEVKKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIS6</accession>
    <name>A0A832XIS6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="230" mass="25826" checksum="66C23F332F6078B8" modified="2021-09-29" version="1">MRNDLASKVEGGLGMKDAVTKGRQYSSGTPNPGKFITTIVMVFLVGLIITLAWAANVGGENEAINAILLLSVIFLLSRMSILNQIGIAFVHIILFGLMLYFSLWLVLSIIVVTTLIMVRINTKPRLIDFAIIKDSQIAITQLIYLSIWTLIISVVFELAGTNGILINLGFYYFLSLTVYMVFFVILTLILTARPVPEVVIRIVLIYMFNWILYHYVLIDFLNYLRSVAPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIY1</accession>
    <name>A0A832XIY1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">8-amino-7-ketopelargonate synthase</fullName>
            <ecNumber evidence="7">2.3.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_03520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42288"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9955"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78846"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="EC" id="2.3.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.47" evidence="7"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010962">
        <property type="entry name" value="AONS_Archaea/Firmicutes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004723">
        <property type="entry name" value="AONS_Archaea/Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00858">
        <property type="entry name" value="bioF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01825">
        <property type="entry name" value="gly_Cac_T_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="8">
        <location>
            <begin position="40"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604723-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="392" mass="43415" checksum="915D235F7134168A" modified="2021-09-29" version="1">MTERTNWLKEEVQNLKDQNLFGELPVMETPAGPRIRINGKDVITLSSNNYLNFTNHPRVIAAAKKAIDDWGFGTGAVRQINGTMTIHNELEKELAEYKGTESSLVFVAGIAANRGTIQALMGPEDAIISDELNHGSIIDGVRLTKSDRKIFPHNDMEGLRKALQETKGARRRLIVADGVFSMDGDISPLDQIVELAEEFDAMVMVDDAHGDGVLGREGRGIVDHFGLHGRVDIDMGTLSKAFGCVGGYIAGDQELRDYLTNRARSFIFTTAHPPAIVQACREAIKIIQDEPEHHKRLWDNTKHFQEQMKDLGFNTGRTQTPITPVIVGEASKAQELSKRMWDEGVFVKPIVFPLVAKDMSRIRANVTAGHTKEDLDECVEKFAKVGKAMGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XKZ6</accession>
    <name>A0A832XKZ6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LPXTG cell wall anchor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="52" mass="5860" checksum="A54E52BD4E0F3230" modified="2021-09-29" version="1">MASDLGLTGLYVTANAMYIEILTRTGSWLLISGLAIIILTAFYIKRKRNQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL25</accession>
    <name>A0A832XL25_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribosome assembly factor SBDS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_00725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SDO1/SBDS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036786">
        <property type="entry name" value="Ribosome_mat_SBDS_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018978">
        <property type="entry name" value="Ribosome_mat_Sdo1/SBDS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019783">
        <property type="entry name" value="Ribosome_mat_Sdo1/SBDS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002140">
        <property type="entry name" value="Sdo1/SBDS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039100">
        <property type="entry name" value="Sdo1/SBDS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037188">
        <property type="entry name" value="Sdo1/SBDS_central_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10927">
        <property type="entry name" value="PTHR10927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01172">
        <property type="entry name" value="SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09377">
        <property type="entry name" value="SBDS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109728">
        <property type="entry name" value="SSF109728"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89895">
        <property type="entry name" value="SSF89895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00291">
        <property type="entry name" value="RNA_SBDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBDS" evidence="2">
        <location>
            <begin position="9"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="SBDS_C" evidence="3">
        <location>
            <begin position="100"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="231" mass="25739" checksum="FB69F0682B512853" modified="2021-09-29" version="1">MVSIEASILARYSSGGKHFEVLVDSDKAQALKAGESVELSELMAVQEVYSDARKAERVTEADLQKVFNTTNPLQVGKEIVLKGEIQLTTDQRRELLDKKKKRISTLIARDAFNPQTGHPHPPNRIEAAMDESKVHIDPLRKAEDQIQKVVEAISKFLPISVEKLRMEVVVPAVHTGKAYGILRNFGIESEQWLDDGSLKVTIKIPAGVEESFYNELNGATQGSFECKKLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL76</accession>
    <name>A0A832XL76_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="491" mass="53249" checksum="3F4ECC48C5C6144A" modified="2021-09-29" version="1">MKLKIIIATFVLFLVLASPILAEGNLQTPRTGDAFNPGDSLLITGSLTSSSSVAGATVEIYAYSRELNQRIPILSKFYSFTEDIPVTISQVNQGVLSWTVSQDSRSSGDWVIYTNVSKGVQVYSLTSSGEFEVSSELSLSYGVNAYKFNLGESLTVTGTVLGIGRNPVDGTAKISFLETVLGTSYMDFSDISGGYFVYSKAFTSSSDEGSFDVTISAEDGSNNSALSGTFSVTVTNDLSLSCVISTKDIEPGGTISITGELKDIHGNTLSGVSVTGLITDPASADTLRQDGVTDGNGRYGLDFTLPKLGMAGIYRVSVDAADSSGNEGQCDMSFDLEGSRSLKADQFKLNGTRHYPGDDIILDVKIENDGNVDIDGVIKLYFGDDEVHTFDISIERAETKEISETFSLDTNPGTHIVKLLVIVQGQTLLEKSLDSTVDVLERKEPEKFKLKTSHIISGLIIFLIAYVIIFYWKDARDYLWQRQHRGHLKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLE4</accession>
    <name>A0A832XLE4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phenylalanine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phenylalanyl-tRNA synthetase beta subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_03085</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004531">
        <property type="entry name" value="Phe-tRNA-synth_IIc_bsu_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00471">
        <property type="entry name" value="pheT_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B5" evidence="9">
        <location>
            <begin position="271"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="543" mass="60904" checksum="557AA1179DE81282" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULJ9</accession>
    <name>A0A832ULJ9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Winged helix DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13463">
        <property type="entry name" value="HTH_27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="31"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="117" mass="13112" checksum="380EECAA9A9FFB86" modified="2021-09-29" version="1">MGTETLEENQHQATLENLFLRPKPARLLVSVGSGEKPYALALAKEIDCTYAHTVKLLMKMEELGLVTFNKKGRTKFVELTDHGKDLADEFEILLTRRIPKRMLPAESVVEGSEGKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULM3</accession>
    <name>A0A832ULM3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NFACT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008532">
        <property type="entry name" value="NFACT_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05670">
        <property type="entry name" value="NFACT-R_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NFACT-R_1" evidence="1">
        <location>
            <begin position="364"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="571" mass="64461" checksum="DF45B4A4002A03C3" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULW7</accession>
    <name>A0A832ULW7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF655 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007003">
        <property type="entry name" value="DUF655"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40734">
        <property type="entry name" value="PTHR40734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04919">
        <property type="entry name" value="DUF655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="225" mass="25973" checksum="7D45FD450C2040BD" modified="2021-09-29" version="1">MPSDETAIVLDYLPEGRMESNIPGYRREKNVSQIIGNRFFSLLEVVLREGRSTSASKVLYIGKGVREDVHHIVKRLNYDELTSTGKVELEFTLDKLISEQEERFIKFFNECGPLTTRLHRLELLPGVGKKHMMEIVRIRNMKLFESFEDLTKRVKLLPDPKKLLIKRIIWELRGEDDRGKQIKYKLLVGIPLFADDVPAPEELPEETPAEEAAQESKPEPEASKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UM12</accession>
    <name>A0A832UM12_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Adenylate kinase</fullName>
            <shortName evidence="8">AK</shortName>
            <ecNumber evidence="3 8">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">adkA</name>
        <name evidence="9" type="ORF">H1011_02570</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the archaeal adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="3 8"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00234">
        <property type="entry name" value="Adenylate_kinase_AdkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023477">
        <property type="entry name" value="Adenylate_kinase_AdkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="10"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="190" mass="20337" checksum="A61198D17D0C0BD2" modified="2021-09-29" version="1">MTDRIIAITGVPGSGKTTVLKNAISKAPNVSVVNFAEVMLSVGAELGLGSDHDAIRTQPLDVQRDLQKKAAEKIAKDSKGVTIVDTHATIKTSAGYLPGLPQWILSALNPSTIVIVESSPKDINFRRKMDKSRSRDDEGEAGIELHQSLNRAITLAYSASSGATVKIITNEQNKLEEASKELLDLFGGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UM72</accession>
    <name>A0A832UM72_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-loop NTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="3"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="255" mass="27300" checksum="14F32E9F13F82448" modified="2021-09-29" version="1">MTRYIVVLSGKGGVGKTTTAVNIGASLNDIGQKVVVIDANIITPNVALQLGLPPRPNNNLNGALKQDYSIFDAVSRHSSGLDVIPAGLSIFGAKNGFSGSMRDALSPLEEKYEIVIMDCGIGLWGSDIKTLNAADEVLIVTNPELPALIDSLKALKMAEKMSVPVRGIILNKVTGSSYELKDETVKGILNNYPIIAKIPFDKNVSKSLGARNPIVLNKPNSPAAHAFKRLAGDLVGEKYKTNIFWKTVNKFRGVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPA8</accession>
    <name>A0A832UPA8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable thymidylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">tmk</name>
        <name evidence="4" type="ORF">H1011_00385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="3">
        <location>
            <begin position="16"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="18"/>
            <end position="25"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="199" mass="22645" checksum="D44A8FB87A7315FD" modified="2021-09-29" version="1">MTGKITSDMAGKFIIFEGLDGSGKSTHAKLLSEWLESKALKVLHTKEPSQGKIGKLLRDYLKDTDSGGRVDALLFTADRAEHLEREILPALERGDIVICERYKYSTIAYQAAQGEDMDWLIGLNEFARKPDLSLFLDLESDIALRRSDESEKFEALDFLTTTRENYMKFSDSFIIVDANKNRDDVQNELRRIVGEFLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPK5</accession>
    <name>A0A832UPK5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">5'-nucleotidase SurE</fullName>
            <ecNumber evidence="4">3.1.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">surE</name>
        <name evidence="6" type="ORF">H1011_01080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="4">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="5">
        <location>
            <begin position="4"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="250" mass="26798" checksum="9114412FC2554EA4" modified="2021-09-29" version="1">MKKILVTNDDGIDAPGIKALEESMSELGEVIVVAPLSQQSATGRGFTLGSPVRVNKRDDNHFSVDGVPVDCVFIGMTKLVKDVDLVVSGINIGANLGIHSLMRSGTCGAAFEAANLGVPSIAVSIESTPEEAHNMEGSHLFDEAQKIMKKLVSGIIEKGLPGDVKMLNVNVPIGEPKGVEVTRLGEEYVTPLLKEVEDSVYVIGGVIEPKEKPGTDIYTLHDERKISITPIAIEGFEHGIIDFGEWLKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPL7</accession>
    <name>A0A832UPL7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">trxA</name>
        <name evidence="3" type="ORF">H1011_01235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="1">
        <location>
            <begin position="33"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="110" mass="12401" checksum="B59006B24A5BC4EA" modified="2021-09-29" version="1">MINSIDSEADFTEKVLKAPESTPILIDFFATWCGPCKILSPILDELSEEYKDKVEFYKIDVDQNKAIAESYGVMGIPSIKIFKNGEIIEELTGLQQKEVLSDILERTLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPU3</accession>
    <name>A0A832UPU3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NTP transferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="238"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="278" mass="31582" checksum="B912A259DDDA1888" modified="2021-09-29" version="1">MKCSAVLLSPGLREGKDPSFLDVYGETILEIAFRNAKKAFKRTLVVAENYKGQKAYEKLVDCDVVADMSPDKSFLTRLLIGLKSCKTQYAFVTTCTMPLIDPKTIGMMMSKIEEHEYDAVIPKIGNSLELLHSIYRTGPVSKSLENSIGDLAYDLETALTKMNTLFIPESEFSELDPALSTFFKVGSEIDYQTLKNRYRKKTYRNRLKKASRISSGTSAEIETENTAYYRVPGTEKSHEVVLNKRKNMWSCDCRYFTMRGNYCSHILASQKTREKDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPV9</accession>
    <name>A0A832UPV9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CARDB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011635">
        <property type="entry name" value="CARDB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07705">
        <property type="entry name" value="CARDB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="CARDB" evidence="2">
        <location>
            <begin position="261"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="383" mass="41509" checksum="A2530E10C5B395C0" modified="2021-09-29" version="1">MEIKKILALFILLIAMSQAAYALEGPLNVTFLLPEENIQPGETLEFRMILKNTGASGITNVQYEVVGGPDLTGFPSGVTLLGGVADGSSVSRNIPVAVSGDASSGKHTLSFLIKYLLNSVEQTLVTSFDFDVGSNVLFRISEVTYEGGLLEPGQTSRTYVTLSNIGSDDASEILATFSSSNPEVKSVLEGGTYFVSSIQSSRSSVLEFIIEVESGTEAKVYDSEIELAYKDSKGNKYTETLTLGLPVKGVPNLEVLNTELDNEDFKVEIENLGTAKAKAISVKLIQNGKLMGVKIDNELKPDKLSTLRFKNFKGGTGQLELHYLDDENQEYDETVYVEVPGKAAPISTLTILLLLIVTAETVYIYRKKKGKSLLPFTSSKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQ23</accession>
    <name>A0A832UQ23_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="326" mass="35697" checksum="839326BAB01B4F51" modified="2021-09-29" version="1">MTLEKEMASRSKMLDAAIDAALEGRLEQLSGPMKYHTLPGGKRVRPILCILACELSGGTPDEAVHAASAIELAHSFSLVHDDIVDGDDLRRGKESLWKKYGNSVAINSGDGLFSLSYSEILKIDADSEILVRVMKEFSKSIIKMCEGQSLDLDFESREKVSLDEYIEMSSLKTGAFIEASALIGGILGGASDAQLEALSLYSKNWGLAFQLWDDFIDFSSESTGKTQNSDIKRGKKTSVVCHALSSLESEDRKKLLEILNAPSESTSDELVLEAVSLLEKSGSIDFVKQMAEELLSEAKSALDAFPDSDVKNILLEFADYCIKREF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQ52</accession>
    <name>A0A832UQ52_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_02895</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005958">
        <property type="entry name" value="TyrNic_aminoTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000517">
        <property type="entry name" value="Tyr_transaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="31"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="397" mass="44435" checksum="1F843C322ABD3B45" modified="2021-09-29" version="1">MDINKRIDGMTYAIREIVVNAREVEKEGHDVLKLNIGDPNKYDFDTPDFLKQALADAALGGNNYYGDSEGIPAVCEAIANREKKYKNIDIAPEQYLPTSGASEGMNMVFASLVGSGDNVVMPGPSYPLYISLTNFYGGSPREYRTIEEEGWQPDIDDIRSKVNENTKAIVVINPNNPTGALYPEKLLKEITDIAAENDVPIICDEIYDLIVFDKKFVSTASLADDVNFIVIGGLSKVYFAPGWRIGYMGFKGPDDEINKLKEACYKMARGRLSTNTPAQLALKTAMESDHSYLNDYLPKLKERAKFSFKRLNEIEGISVTEAHGAMYMFPKIELESYKGRDKQFVLDLLKEKHVLTVQGSGFGEQYGGDHFRIVFLPPMETLANAFDKLEDFCKSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UT13</accession>
    <name>A0A832UT13_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Acidic ribosomal protein P0 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplJ</name>
        <name evidence="2" type="synonym">rpl10</name>
        <name evidence="2" type="synonym">rplP0</name>
        <name evidence="5" type="ORF">H1011_00260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00280">
        <property type="entry name" value="Ribosomal_L10_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022909">
        <property type="entry name" value="50S_L10_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="RL10_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="RL10P_insert"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RL10P_insert" evidence="4">
        <location>
            <begin position="106"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="283"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="283"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="323"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="359" mass="39003" checksum="66D663EBB65F13F9" modified="2021-09-29" version="1">MREGEVPQKKVDLVNDLVSLINENSVVAVVDISNLPSKQLLQMKHALRGKAVVRMARKSAISRALEQTDGKGLVEYLKGMPALLVSSENPFMLSKILKESKATAPAKEGTTLNKDIVIPAGETSFAPGPIVGELQTMGVKAAIEGGKVVVKEDSVLAKEGEVVDKQKADLMAKLELEPVEIGLGIVAAYENGLIFTSDVLDIDTEETLGQLAAAAANAFSLSYSIKYPTSDNIEMFIKEAFVQAKGLAMEAGYMCSATAEDFLKQAVREASVLESKVPEVPVELLKEESEEKSEETSSEKESKDEKSEEEPAEEASTEESKEETPAEEEKPAKEEKPIEEKSTEDLLAQNEEEIEKEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UT92</accession>
    <name>A0A832UT92_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HesA/MoeB/ThiF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="8"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="308" mass="33487" checksum="DB44B22687073113" modified="2021-09-29" version="1" fragment="single">MSSEIHARQQLAIGKKEQRKLENSRVCIVGVGGTGCAVAGLLGRAGLGLILVDRDIVEKSNLGRQILYTEKDIGTLKALAAKKNILAANPDAKITAITDELKAENAERFLNTDLIIDCTDNIAARFLINEVSLKKKIPWIYTGAIKNEGMIAIFSGAGKPCFRCMVPRVPKAGSLEICSTAGVLGPLPSVVGSIAARSAIEILLGHSENGKLLKIGDEFEMLNIKEREWCDTCKKEFPILTGRENLEKSMQFCGAIVLKSDVPFSEARKRMKKNSKIISSSGTAIVSEHKNSRVIPLKSGKIIFRNVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTA9</accession>
    <name>A0A832UTA9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">AA_kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_00965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_kinase" evidence="3">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="259" mass="28656" checksum="17274D1AED7FFBBD" modified="2021-09-29" version="1">MFIVKIGGSVLSQSEEIVKDLANYKDFIVVHGSGPQVDKLTKERLGKEPRWVYSVSGVKCRYTDSEVILLHQEVCREQTSKLVELLKTNGMDAIGFAESPIIFAKRKEAIKVIENKKKYILREDQSGKIERIDSESLNSVLSKGKIPVIPPLAIGHNGEPLNVNGDRVCAYLARELGVDTIINLSNIPGFLRNEKVVPEIKLNELEQLRKETRGGMSIKLIGVQEAMNFGVQKFVISSGEIDKPVTSALDGKGTVFLHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTV9</accession>
    <name>A0A832UTV9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045901">
        <property type="term" value="P:positive regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045905">
        <property type="term" value="P:positive regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019769">
        <property type="entry name" value="Trans_elong_IF5A_hypusine_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00302">
        <property type="entry name" value="IF5A_HYPUSINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="146" mass="16409" checksum="6DD8B2466F612CD9" modified="2021-09-29" version="1">MTTSSVIATRLKQGDLFLLDGKGDEIFKVKKLNTSSPGKHGHAKVRIMYVNFFTGSGGEVTYSGHKEMDKPVIEKERSQIISITPGKTSNDPNVPHVPAELQLMHLETFETYELPCPSEIPEPDLVVGKEVEVRKFESRKWIEKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTW9</accession>
    <name>A0A832UTW9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe-S cluster assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufB</name>
        <name evidence="3" type="ORF">H1011_02470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="135"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="475" mass="53107" checksum="F513098F1C3AF2E4" modified="2021-09-29" version="1">MTDSQILEKQKLATKINRERFDHANEERHRLKPDPGLREEVVRLISSEKNEPDWMLEHRLKCLNIFEKIPMPSWGPNLDKLDLNKIHFYMSPDAERNSKTWDDVPEDIKNTFEKLGIPEAEQKSLAGVGAQYESDVVYHNLKKEWETQGVVFLDMDVGVQEYPELVKKHFMTKCIPPSLHKFAALHGAVWSGGTFLYIPEGVKVDMPLQAYFRMNSEAGGQFEHTLLIADKNSEFHYIEGCSAPKYDAYSLHAGGVEIFINEGAKGRYSSVENWSKTTFNLNTKRGLVEKNGTLEWVNGNMGSCVTMLYPSSLLIGRGARSDYLGIAFASGDQNQDTGSKMYHLAPNTSSTITAKSISKGGGVTSYRGYLGISKGAVDSKASVQCDALLVDDISVSNTYPYMKINEDAVDVAHEASVGKISSDDIFYLMSRGLNEIEAKKMIVSGFIEPIVKELPLEYAVELNRLIEMEMEGSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UU13</accession>
    <name>A0A832UU13_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="6"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="106" mass="12220" checksum="0FDA3F2FE044CD06" modified="2021-09-29" version="1">MAEEVENVKTETQAGDEAYLLDFYGTECTHCHEMDPLTERLQKEEGMKIKKIEVWHNAQNAAYLQELDQGKCGGVPYFYNLRTKKGLCGAVKYEKLKEWALEEPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UXT3</accession>
    <name>A0A832UXT3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_00230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040825">
        <property type="entry name" value="FKBP26_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18046">
        <property type="entry name" value="FKBP26_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="3">
        <location>
            <begin position="8"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="228" mass="25509" checksum="F1A8923F8A658184" modified="2021-09-29" version="1">MVDKISKGDFINVDYTGSEKDTGRVFDTTNEVLAKKENIYNEDSKFGTITLVVGAGHVLPGLDKELTSLSVGDKKKITISKEDAFGSKDSDLVKLVPRSVFKRSRMNPVPGMPVEVGGRQGIVKTVSGGRINVDFNHPLAGKELEYEIEVKGKVTDQKEKVLSFFYLHLPKLDLKDLDIKISSGIAEIRTPNDENTRRYISMVKPIISRDILNYISEIKRITFIDVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UXU0</accession>
    <name>A0A832UXU0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="216" mass="23737" checksum="20306B2D1360BD31" modified="2021-09-29" version="1">MVSHHRSRKAQSPVISSVVMILVVTALVILTFTWGNEMLETQQVSVTVTYSQAKLLDIKNAILEVAQEQINSTRIVRMNLRMGSLSVLNGSHCSGANVNKNAILYNLTHNRKLIDSLDWVSIDPIEPNFRCSANQTNGSSGVLVARPFKAGNSYANSFMIWFRQINDTTSSTSYLINISIGEVSRISGTSTTIIARNIGRVNSSGTIHTNVLVDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UY81</accession>
    <name>A0A832UY81_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="36"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="115" mass="13373" checksum="0C01F1F064C5DEE2" modified="2021-09-29" version="1">MKFNFDTFKDVANLVKSTERYDLYDMKLDHLTLSMTRMKPKQETRGHDHEGVEEVYFCLDGEGQIQVGEEKVDFKKGDVVTIPPGDFHKVFNPSDSELVFFSIFESYDRDSANYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYD6</accession>
    <name>A0A832UYD6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000010">
        <property type="protein sequence ID" value="HIJ99538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="82" mass="9540" checksum="50411B0EAD71AC9B" modified="2021-09-29" version="1">MVEQEYLEELKRAVLELEGHANMFSFEDLENYAKGHGIPEKEVDGLIHELIAEEYIHKIHGTELYSRTVHKDYSQAAEKQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYK0</accession>
    <name>A0A832UYK0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AI-2E family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_02365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="352" mass="39235" checksum="305AFA7918DF95C6" modified="2021-09-29" version="1">MAIHRWRFIGIFILLAILGGAAMVMWNFVGLLLISFAMAYIIYPLAGYFSGGDRKAGRKYLTACLSSVLLVALPVIYILIYSLNVILQWLIENFGMIQSGSFTEGLKSGLDSAGFGVVSERLGSELGRLISSATDAVWSQVIQPTWFLETSISLALFFVATFYFLYEGPRLMELIRNHIPSREKFLHELMSTIDKIFYGLFIGHLLTSVIIAGLAAIGFWAILRPPLLTLGFLVGMMFVVSFLPLIGPWLMYVPMGLWYMILLPGGTMSGILILIYGALMLTIVPDFYIRPKLVRRDADIHPLLILLGFFGGPFVMGFKGIIIGPLVLGLAQAIVMLYIEKRHMLEDLFSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZ00</accession>
    <name>A0A832UZ00_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000017">
        <property type="protein sequence ID" value="HIJ99883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="135" mass="15633" checksum="66313BCF98B585C9" modified="2021-09-29" version="1" fragment="single">MEKVGSVDYFDGAKRRLYFFVERENFVEEEGFYKVVSGDKIFYIFVTSLSEHPLESDVGSRYSPAGFDFDFGERFLLYGQASVLLEYRKEGNTKIVGYKTIPRHGSGIYELEESDFDILQLPKLDFAYVRSGSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZ66</accession>
    <name>A0A832UZ66_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Zn_ribbon_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025868">
        <property type="entry name" value="Zn_ribbon_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12674">
        <property type="entry name" value="Zn_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_ribbon_2" evidence="1">
        <location>
            <begin position="6"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12674"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="85" mass="9577" checksum="BEB4525CF956FDC9" modified="2021-09-29" version="1">MEGNPCESCNRPMHSEKNHGGGFAGNPYCDFCTDGDGNLNSFEEIRKGMVDFAVSRDDIGTREAQEVANQHLRKMPAWRHLYEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZ86</accession>
    <name>A0A832UZ86_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="107" mass="11709" checksum="70206E4015E11494" modified="2021-09-29" version="1">MFEILLFTVLGCFLGTFTGIVAYFLQVKIGEFAAMHLGKVSGSSYRKLTSAVILLVVILVFVMTGFLGLIILLIGTIIGLFPPNLGVRRAQCMGFFLIPVLLFYSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZA8</accession>
    <name>A0A832UZA8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_01375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030382">
        <property type="entry name" value="MeTrfase_TRM5/TYW2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02475">
        <property type="entry name" value="Met_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51684">
        <property type="entry name" value="SAM_MT_TRM5_TYW2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_TRM5_TYW2" evidence="3">
        <location>
            <begin position="32"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="280" mass="31404" checksum="E8029AC6214A4240" modified="2021-09-29" version="1">MDSKKVKRPKSLKEALKGKLTESEMKLLGRAFDYLGEIAIIEIPEELHHKEKLIGEALLKVHKALRAVFRKSGKVSGEHRTRSLKRIAGSGSAETTYKENACAYHFDAEAVFFTGRLSTERQRVSDLIGKKEKVLDMFAGVGPYTILIAKEHPETKLTAIDTNEAAINYLQKNAELNKVSSQIITLIGDASEVASELKQKFDRIIMNLPAGCSGHIPVAVKALKKKGIIHYYFFSSTTEEAKEEVERVFSDYNSKILKIKKVKPYSPRTFTFVADVELSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZG9</accession>
    <name>A0A832UZG9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="8">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">argS</name>
        <name evidence="13" type="ORF">H1011_00345</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="8"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="12">
        <location>
            <begin position="109"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="562"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="HIJ99260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="678" mass="78359" checksum="889C826166CA4283" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZM7</accession>
    <name>A0A832UZM7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA repair exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="1"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="412" mass="46264" checksum="A235E3DF57B91AD5" modified="2021-09-29" version="1">MRVAIISDLHFGFANASEREEDSFIQGREAIEAALDGKADVILIAGDVFDSRVPTQDILAKTMEIFQEPLHAKSSKVKVVDSINKKRGEIAQAPFRGVPVIAIHGTHERRGRGLTNPLQVTEKAGLLVHLHCQTIVLEVGGEKLAVHGLSGVPERYAKDVLEEWNPKAVEGATNILLLHQNIDEFLYTGTDFKSLELADMPKGFDLVVNGHIHWACQDELKQGGKFLIPGSSIRTQLTKQESEIEKRIYFFENGELEFKKLESPREFHYKTLEINEGTPSSIISELESFLEEIPTKERKPLVKVILKGSLKKGYSKTDISLSYLEKKFKSKLILRIAKNKLESETVLDRSDLLSKKEGRAISIEERGQELLKMHLGEIQFEFGIEQDELLGILSTDSKEMALQKIKEAVRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZP6</accession>
    <name>A0A832UZP6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_02410</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="7">
        <location>
            <begin position="206"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="282" mass="30261" checksum="8E4366E9AC64630B" modified="2021-09-29" version="1">MEKSGSIATTVGVVVNTILFVLKLVVGISTGSLAVISDAINSLTDVLTAIAVAISFRISRKKADPGHMYGYRRAEPVAGLIVALFAGLAAYEIITAAVSRIINPTDVFFSWLAIGVLAMSVIVKAVMSIYHTKVSEKLSSPSIKAIAIDGRYDSISSAVALVGVIGTKYFPLADSIAAGLVAFFILWAGYRIASENMNYLMGATPDPEMVNSIRNTAKEVRGVIGIGAVRPHYVGNQVHVEIEIYVDEKDTVTLVHKIQEEVRDDIEALEGIEEAFVHIVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZS3</accession>
    <name>A0A832UZS3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">V-type ATP synthase subunit I</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_01205</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the V-ATPase 116 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033179">
        <property type="term" value="C:proton-transporting V-type ATPase, V0 domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002490">
        <property type="entry name" value="V-ATPase_116kDa_su"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11629">
        <property type="entry name" value="PTHR11629"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01496">
        <property type="entry name" value="V_ATPase_I"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="352"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="498"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="532"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="564"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="615" mass="68571" checksum="A98E0EFF9776970D" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZT5</accession>
    <name>A0A832UZT5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-layer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022651">
        <property type="entry name" value="S_layer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006454">
        <property type="entry name" value="S_layer_MJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022650">
        <property type="entry name" value="S_layer_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05124">
        <property type="entry name" value="S_layer_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05123">
        <property type="entry name" value="S_layer_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01564">
        <property type="entry name" value="S_layer_MJ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S_layer_N" evidence="1">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="S_layer_C" evidence="2">
        <location>
            <begin position="617"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="756" mass="79092" checksum="4EF8977457DB9237" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZU4</accession>
    <name>A0A832UZU4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Dolichyl-phosphooligosaccharide-protein glycotransferase</fullName>
            <ecNumber evidence="6">2.4.99.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Oligosaccharyl transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">H1011_01440</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Protein modification; protein glycosylation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the STT3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.21" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00378"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004576">
        <property type="term" value="F:oligosaccharyl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006486">
        <property type="term" value="P:protein glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003674">
        <property type="entry name" value="Oligo_trans_STT3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13872">
        <property type="entry name" value="PTHR13872"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02516">
        <property type="entry name" value="STT3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0464">Manganese</keyword>
    <keyword evidence="13 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <keyword evidence="9 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="150"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="379"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="408"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="HIJ99470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="675" mass="75867" checksum="0AECD335D3722426" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZW6</accession>
    <name>A0A832UZW6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="10">RnfABCDGE type electron transport complex subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_02875</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004338">
        <property type="entry name" value="NqrB/RnfD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03116">
        <property type="entry name" value="NQR2_RnfD_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0288">FMN</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="107"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="251" mass="27680" checksum="C78C3AD93CD7CBBF" modified="2021-09-29" version="1">MKLSLKTIRDADWRYYVGSIILILAFLSALDTGFSLFRNVFIALATTIGTDYTYNRVVRKKSFWPRSAVVSGLLIGVILQGLWWHTVIAAVLAILLKRTIRWKGHNIFNPAALGMLVAGIFLPISLVWSASAVPLATIVLGLLLAYIIGRIPLILAYFAAHAVFMAGYSLLTGTPFIDNFMFIEFFMVFLMLVEPVTSPSKRNIRLVYGVVAAVLINILILTIGWFSFLPAFDPVLTGLLGANLVGRALSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZY9</accession>
    <name>A0A832UZY9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CARDB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_03035</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011635">
        <property type="entry name" value="CARDB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07705">
        <property type="entry name" value="CARDB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="500"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="domain" description="CARDB" evidence="3">
        <location>
            <begin position="26"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="600"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="661"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="600"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="663"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="713" mass="78711" checksum="F9F48A3A12188097" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V023</accession>
    <name>A0A832V023_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045509">
        <property type="entry name" value="HD_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19276">
        <property type="entry name" value="HD_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="50"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="394" mass="44498" checksum="897354DB75276D51" modified="2021-09-29" version="1">MKIIRDPIHGNLTISRDELQVLDAPEMQRLRRVRQLGFVYFVYPSATHSRFEHSLGAFHIAGRIAEAVGLENDEAEQVKLAALLHDLGHGPYSHSSEIASNFFKKTTHEMYTSKIIRKSAVSDALKDTGHNPDEIAKIATGRKKPNSDIVSGDIDADRMDYLMRDSYYTGAAYGIVDLDHLLLKLMMTKQGLVVDEEGLSAVESMLIARYLMYPAVYSHKTSRIADSMFTNALIECLQEKAFTIDELFRMDDAEVFQKIRSHGGEGENLLDSIERRDLHKAALRLSKEDFGKSFEEIMSLKSDIKNLKKLEAEITEECGLERNELLLDVPPPQYTKEVKTLISDSGKLKKLEEFSPLVKALREAQWKYWNVGVYASAGDLEKVSKKAKEILLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V053</accession>
    <name>A0A832V053_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calcium/sodium antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_02400</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00367">
        <property type="entry name" value="TIGR00367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="9"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="172"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="311" mass="32673" checksum="A4349C01CB0ABF22" modified="2021-09-29" version="1">MIAGFPLESVGIFIISIAILLKGATVFTNRSVYIARQLGISDFAIGLTLVAFSTSLPELAISMTASLSGSDGIAIGNIIGSNIANIGLIIGIAAIFMPLVLKKEDFKQALLMIAVLFLGSIFMYNGLSRLEGLILVSVLIAYVINALRQGKVGTAKASKGRSLSSNLFFAFAGAGAVVVGGKFVVDSSVVIARWAGISEVLIGITIIAIGTSLPELVTSLIAAKNNMPGMAIGNIIGSNIFNIAAVLGLTSLISPISVSLDVFLFDIPAMMLFSIILASFMYFGANRISKKSGIYLLTLYVIYLGVHIFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V064</accession>
    <name>A0A832V064_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fe-S cluster assembly protein SufD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">sufD</name>
        <name evidence="1" type="ORF">H1011_02475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="398" mass="44256" checksum="ADE1D0B167FFDC0F" modified="2021-09-29" version="1">MSSELSIDAIRVFSAGRDEPKWLLKKRLDGLKQFEKFEAPTFSYGLGINLNTDTLDLEIAVPKNLWSVASEITSTADKEIIVKKLSDAVKDEDLKDYLFKTSPINKIEALHQAVWSEGLFVKIPEGKEVKTPVNITSDAKAIAIAEHNLFIAEPGSKMTVVQKSIGKPQFKTANSEIHVQDSARIQYGEFQNLSEKTNYFSKKIAYVQKDATIDWIACDIGARFGGVTLITNLEGRGSKVSSRSMFFGRGEQNFDFYLVANHKAKDTTSYLDVKGALDGKSKAIYRGLVRIEKGAPNSDGYQNEETLLLSSDAEASAVPNLEIDNNDVKCSHGTAIGQIDKSKLFYMMTRGMDEITAKRKLVEGFFEPFIQKIPVDVVKADLKKIILERIGGINELKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V067</accession>
    <name>A0A832V067_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Proteasome subunit beta</fullName>
            <ecNumber evidence="9">3.4.25.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">20S proteasome beta subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Proteasome core protein PsmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">psmB</name>
        <name evidence="11" type="ORF">H1011_00775</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="9"/>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02113_A">
        <property type="entry name" value="Proteasome_B_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019983">
        <property type="entry name" value="Pept_T1A_Psome_bsu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03634">
        <property type="entry name" value="arc_protsome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="7 9 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="8 9" id="KW-0865">Zymogen</keyword>
    <feature type="propeptide" id="PRO_5033192935" description="Removed in mature form; by autocatalysis" evidence="9">
        <location>
            <begin position="1"/>
            <end position="7"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033192934" description="Proteasome subunit beta" evidence="9">
        <location>
            <begin position="8"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="205" mass="22072" checksum="A3D0BA35F9E6A65C" modified="2021-09-29" version="1">MQKYLKGTTTLAFICKDGVVVGSDTRSTMGFLISDKKSKKIYNIDDRMALTTAGLVGDNVTLVRIMKAQAALSRLEKKPLTVKGAANLLSNILYSRRGFPFMVQLVLAGYDSEPHVYELDAVGGMSEKSVSATGSGSPTAYGVLESEYSEGMSMEDGIKLATKAVKSAIERDAASGNHIDIVTVTKDGYAEVPQETIKEILKSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V072</accession>
    <name>A0A832V072_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="75"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="120" mass="12935" checksum="3BF0272EBFD92E87" modified="2021-09-29" version="1">MIKVGTVCTKTAGRENGNICIILENIDDIFVIVAGPSVRKKRCNVKHLSQLPRELIVSKGASRADASKLLADAGLVEESEESAPKKKTDAKTPAKKPVKKAEKKKDSKKAVSKKTVPAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V096</accession>
    <name>A0A832V096_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="6">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Leucine aminopeptidase</fullName>
            <shortName evidence="6">LAP</shortName>
            <ecNumber evidence="6">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pepA</name>
        <name evidence="8" type="ORF">H1011_01085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="6"/>
    <dbReference type="EC" id="3.4.11.10" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008283">
        <property type="entry name" value="Peptidase_M17_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02789">
        <property type="entry name" value="Peptidase_M17_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00631">
        <property type="entry name" value="CYTOSOL_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 8" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0464">Manganese</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="7">
        <location>
            <begin position="335"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="487" mass="52081" checksum="8E405D69D8C57B81" modified="2021-09-29" version="1">MKVNVSSEGSDRVKADLLAFAVYEGSGISKDLQKIDSSLGSAISKAIKLKRFSGKCGETYMLQTYGKLSVECILLVGMGKKEEFELDHVRKYAGASICSAKVMKAKSLAISMPSCKEKVSDVSHALAEGCVLADYVFDDYVTKTETENNLAVSILSGDKKSTDYGVLVAESINYTRKLQNFPPAVVTPAYLASEAQRMGKELKLKVSVLGNKELEKKGMNGILAVGKGSVNEPRLIQLDYNGGKTGEKPVILVGKGITFDTGGISIKPSRAMDEMKFDMSGAAAVLGIMRIAAKSGLKKNLIGLMACAENRPSSSSYLPGDIIKTYNKKTIEVLNTDAEGRVVLSDALGYAAEMKSEIIVDIATLTGSVVVALGSTYSGMVGNSQRHMDLMRKAGEKTGDKVWQMPLHEDYREMVKSKIADVKNIGSGKGEAGSLSAAAFLEAFVGDSKWIHLDIAGTAWTTEPKPYFGLGGTGAGVHVISEFLRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0B4</accession>
    <name>A0A832V0B4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PRC-barrel domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="85" mass="9388" checksum="81D277F482F8533D" modified="2021-09-29" version="1">MARIPFKEVQTKTVVSEGGRMFGKVLDITVDVGTGELINLIVEPTKYILAHFEDLVRDKKGRILLPFSAVTAVGDFVLVNENDVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0I3</accession>
    <name>A0A832V0I3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="47" mass="5509" checksum="070DC400FE44C5B9" modified="2021-09-29" version="1">MPAKLLLGVYGIYVLVKLLLVAFLGAVIVRKYRNFFNRVIPQRFRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0I8</accession>
    <name>A0A832V0I8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="74" mass="7889" checksum="F94F51B25403D68C" modified="2021-09-29" version="1">MVIKFGQSTISLQEVGSSSENEESLTESSSEEAEESTEEGTLAKCPNCEQNTLKIEQGCSSCTNPECGMSKCDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0K7</accession>
    <name>A0A832V0K7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_02195</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="16"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="270"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="366" mass="39829" checksum="EAEF7DDC8237944A" modified="2021-09-29" version="1">MIDLALKDLRSHRMRTFLTILGIVIGITTIVSLGSISSGINSLVEGQLNIVSGKIVVTQHGAEPASGPPSGKVSTDIVDEIRQISGVEEVAGMRLEHWGDFMINGAELDKRDSIGLGQVELEEGDWAEVGAYEVTMGYHAKEQYDLNLGDSISVEGVDLRVVGHLEEVGGFMDFGLITSWVILDEIFEDGDFFTIVFVKPQDLSISKEISEKIKEEFPELSVETTESASENARESLAQIRLITFGIGFIATIVAMFGIINTMIMSVHEKRRQIGIMKAIGATKRQIVTRFFEESIIMGLVGSFVGLFFGYLGTSALNVQIGMKMARVTPGLVAFSVIFAMSITIIATIYPAIKAMKVDPISAIRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0L5</accession>
    <name>A0A832V0L5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000019">
        <property type="protein sequence ID" value="HIJ99905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="452" mass="48166" checksum="515A734A9A508652" modified="2021-09-29" version="1">MEKSSTVHNKFFLTLIVLSATLLIAGCTGGDTGAAAGTAGADSLIISIDTEGRDLFDSNEAFLISVQAENIGPVNAENVKVRLQGYDGISSGTSLGTYVSLSPLALERPNREEGLAGGVGNIEWDVIAPYVSATSPDREISLTAAVRYDTKSIVSQKVVIAEASHLTELEARGERVPASPTQEARNGPVGIAMEAPAPYVRMSGSEDEFILRITIYNDGSGTVYDAASERDRVSSIRLSVPSGLTVDESKCDFDLRTSNSLDGVKVLLIDSSSSSAKQNKLRLTEGGYTRTVQCHLQSYSERVNGYNTFAIESEVSYRYVQSVSTTLDIIGTSEGALALEITDPSTTSQRTWGSSSSEEILFTLTYQGEPVTDINPSFDVTSASYLNFTLFNGSTELNVPVSTSGNSYTDGVWNVTVTAPTGTTTDHITLRGTANYLGETAADRNVNSVELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1J4</accession>
    <name>A0A832V1J4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L37Ae</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Ribosomal protein L43e</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpl37ae</name>
        <name evidence="4" type="ORF">H1011_00745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00327">
        <property type="entry name" value="Ribosomal_L37Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013955">
        <property type="entry name" value="Rep_factor-A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_L37ae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_L37ae/L37e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08646">
        <property type="entry name" value="Rep_fac-A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Rep_fac-A_C" evidence="3">
        <location>
            <begin position="25"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="2">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="103" mass="11612" checksum="D82A9B8D159F6502" modified="2021-09-29" version="1">MRTKQVGSSGRFGQRYGRRVRLRTATIEKHSKAYHPCPSCKAKKVRREFAGVWRCRKCNMQFSGGAYSPSSSIEEIKARFTSAVVLQKTKSPGQSQEESLDVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1L5</accession>
    <name>A0A832V1L5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_00895</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="484"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="518" mass="55716" checksum="11BCE191EBD786EE" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1P5</accession>
    <name>A0A832V1P5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DEAD/DEAH box helicase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_01135</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12089">
        <property type="entry name" value="Hef_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039686">
        <property type="entry name" value="FANCM/Mph1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041755">
        <property type="entry name" value="Hef_ID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="PTHR14025:SF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="4">
        <location>
            <begin position="20"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="5">
        <location>
            <begin position="342"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="724" mass="81722" checksum="76916C9350B81E44" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1Q3</accession>
    <name>A0A832V1Q3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="105" mass="12066" checksum="EE3006E87A8F016E" modified="2021-09-29" version="1">MSKEDIIRRINKIEQEGSEKILLAETGKKLKLAEAEKYSSGLLEKFHENSAVYAQERIDTERKNQMKRAKRSLSVAGGKAAKLEESAKKKMTKAIDYIFKEFMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1T4</accession>
    <name>A0A832V1T4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">H1011_01445</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028357">
        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="315"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="158"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="255"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="412" mass="44435" checksum="21A6A05CED07C4EA" modified="2021-09-29" version="1">MKVSVIGTGYVGLISGVGYASQGHDVICVDVLEEKVAKINAGEPPIHEAGLPERLRQVLDKGNFKATTDITDAIENSDICFISVGTPSAADGSIDLKYIEQASKDLGTALKNKDSYFTIVVKSTVTPGTTEGTVIKNVEAASGKKAGQDFGVCMNPEFLREGKAIEDFDNPDRIVIGRLDEKSSEALKALNKAFTCPVLETPLSTAEMIKYVSNAFLAVKISYANEVAEFCKKIGADPYEVFKGVGMDKRINPAFFNSGLGWGGSCFPKDTKEFAAAAKREGANPRIVDAAIETNKILPSKIVELAGDVSGKTVAVLGLAFKAGTDDVRESQAVEVIKLLNEKGAKIQAYDPEASEVEGLEREETMEKALEGAEICLVLTEWPEFENIPFSGKIIDGRNIVENRENYEGLFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1U6</accession>
    <name>A0A832V1U6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="197" mass="21824" checksum="38B3E175241C014B" modified="2021-09-29" version="1">EDYDAYTTGGSNKFDPWAESPVDCYDQSLSGFQRQSCVIRQCDCDLGQLYIGPGTDELEDTDCNGYENPTKTISVGTPPVTQTIAMEIGDRCWDVYQASMSSSALSYAVFTTTKTTLEGVVNDYITNYNTRYGIVSYSVPWVSGFLFTEESDYLEIVTVFNEELNPPSLKIASKGVTMNAGESMTIEIHNPMDFCVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V259</accession>
    <name>A0A832V259_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cation:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_02405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="9"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="387" mass="42280" checksum="045A47C6661175DB" modified="2021-09-29" version="1">MIDLLVSVIILLFLARLCGALAEIIGLSAIVGEIFAGISVGSTLFPQFTYLFTESVLLEGMADIGIIFLIFLVGLKINLKSFEKFLRTGAIIAMFGAFIPFFAGTYLGFAYFSWNPVQSLFLGGIMMASSMAIAGRMLYDCRLLNKRVGTLAIDAVLVGELLSLLMLIFLVQLVNNSTFSLQSLAKSTVYVAVFFAAVILLGKYISKYIEILGKFLNLRVKEGLLSMVIILVFTLSLIAEAIGVSMVIGAFLAGLVLHERHLKKIEHEIYSMAYGLFIPLFFALLGVYVNLFEMIAMWPLLLSIFSVAVISRLFSAYLGARVSGMNSKNSFIISLVMTPRAEVAFIISSVALLNGVFSSSVYSAVIGALILTIVVVPPVFRRVVWTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2J3</accession>
    <name>A0A832V2J3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OB-fold nucleic acid binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OB" evidence="1">
        <location>
            <begin position="42"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="200" mass="21773" checksum="0EAC2335BF140CDA" modified="2021-09-29" version="1">MTENSQLASKKVHIDKIVSGEYVESEGYGVLRAADGSELSRVRILGTIVDKFVSADGEYSSVTLDDSSETIRAKAFKKRASTLAKLEVGDIADVTGTIREYDDEIYINSFVAQKIIDPNFELLRRIELAQPGESQPGNSHEDVEALILKTISDTGADGASLEVLASVLKDLDDNDILAAVKSLLHKGDLYEPVRGVFKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2M6</accession>
    <name>A0A832V2M6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methionine adenosyltransferase</fullName>
            <ecNumber evidence="6">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">H1011_03625</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="13" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="5"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="117"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="236"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="HIJ99876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="387" mass="42649" checksum="B445BACA5F95F122" modified="2021-09-29" version="1">MIRGKYHFTSESVTEGHPDKLCDQISDGVLDAILEKDPEARVAVETLATTGLVVVAGEVSTEAYIDIQEVVRKVIKEAGYDKLGESGFNYDDCSVLVSLHEQSPDIAKGVRKKTKEKQGAGDQGLMFGYATNETEEFMPLPIMLSHKITQRMAKLRKNGDIPWIRTDGKAQVTIEYEDGKPIRADTIVVSTQHSSNVKHEQIVKEIKKKVILPVCENWVDEKTNYFINPTGAFIRGGPGADTGLTGRKIIVDTYGGVGSHGGGCFSGKDPSKVDRSASYMARHVAKNIVAAELADKCEVQIAYAIGVSEPVSVYIDTFGTGKYPETEIKAAVLKVFDLRPGKIIDYLNLKRPIYRKTAAYGHFGRSEAEFTWEKTDRVRELKELIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3H5</accession>
    <name>A0A832V3H5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="58" mass="6369" checksum="06FB712B49A31B0E" modified="2021-09-29" version="1">MTNLPDYKAVVKTGDKRWDELGAGWSKENGNISLQLKVAPLPSEGKVNFLLVPNATEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3K9</accession>
    <name>A0A832V3K9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="395" mass="45166" checksum="09C385A5D499D1C8" modified="2021-09-29" version="1">GDDPDRRYREIEIGDIDGDGKNEIILLKNLKYPTRSPQCPEDDPDSYYFNKLIDYKGVAVVVFGMNDYIKASKESAFPIEGIDSIIRTRYGEWRIYELESEFNGCDLEGEGNEAWGMSKNAIEVIDFDGDGKDEILLFAEQKIFVIEEDANGDLTHYVIDQDAQYHHSGGISKHDFFLLGNINIGKDYEALYIFRNPDITQTDVKIGVTQLIFNEEDGTYESVKTKDMDTWNIPENSWYEDATICDFDHDGWDDELVLIRGEKRSPYIGASTLQPSDFRLQIYEFEQNSDGEIWINSEPLHTTNKLPYRGRWEELVCDDFDGDGWDEVVLIPLGISTEQDVEGTIYVLETENILTLGDDVYNYGIEEIRNKLPWGILEIGDRAWISIAGGNLIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3U6</accession>
    <name>A0A832V3U6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="297" mass="33047" checksum="5DAC4B870ECB08DB" modified="2021-09-29" version="1">MEISVVIPSYNEEGNVERLYMELATVLTRMKKSHEILFVDDGSSDGTVGKLEKIAKHDKSVKLIKHGSNKGQTAALLTGFKVSRGRIVISMDADLQNDPSDIPKLVEGLEKADVVCGWRADRKDSFGKRMASKLNNFLVRRFFGLSLHDQGCTLRAYKSSAIKDLELHGEGHRYIPAMLSVKGHKVIEMKVKHHERKSGKTKYGLSRLPKGFLDLITLKFLTSYGSRPIHIFGAAGFALMGLGFLGGVKLLYDKYVLGHGIGSRPLLILVVLLVLLGMQFIFNGLLAELIIRTRERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3V7</accession>
    <name>A0A832V3V7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ZIP family metal transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_01610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="247" mass="26672" checksum="A68B927589A9A835" modified="2021-09-29" version="1">MEISWIYAIISVIIVSLVSLVGVFILSSRKSLLENNLLYLVSFATGAILGNVFLHLIPEIVQTNGFGLEISLYILAGLLTAFVIEKIVHWKHMHKAGESHVHPISYLILIGDGIHNFIDGMVIGAVYLTNIPIGIATTISIIFHEIPQEIGDFSILINSGMTRAKALFYNFVSALTALLGTAIVLVIGSTTPSLEGILIPFAVGNFIYIAAADLIPEMHKETELSKSAIQFLTFLAGIGIMLVLALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V455</accession>
    <name>A0A832V455_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Prefoldin subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GimC subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">pfdA</name>
        <name evidence="7" type="ORF">H1011_02730</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterohexamer of two alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the prefoldin alpha subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the prefoldin subunit alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00308">
        <property type="entry name" value="PfdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011599">
        <property type="entry name" value="PFD_alpha_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004127">
        <property type="entry name" value="Prefoldin_subunit_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12674">
        <property type="entry name" value="PTHR12674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02996">
        <property type="entry name" value="Prefoldin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00293">
        <property type="entry name" value="TIGR00293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="4"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="141" mass="15894" checksum="0EF820183F2CBAAD" modified="2021-09-29" version="1">MTDNKNLQETIENYNMKKAQIENLAREMEALANTQASLDVSKEALEELDGAEKGKEMLVPVGVNTFVKAVIEDPSKVIRGIGAGLFKDSDIKEALKETEEAAKNFENIKNNIETEFKKTAKEMEKLEPELEKMMAERKTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V7U9</accession>
    <name>A0A832V7U9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_00215</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="3"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="100"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="200" mass="22900" checksum="71A8DAD53334C080" modified="2021-09-29" version="1">MASHELPKLNYAYDALEPFIDAQTMEIHHSKHHQAYVNNLNKALDGQDELAKLSPSELLKDLSVIPDDIRQTVINHGGGHANHTFFWTLLEKDVEIPEPFMEALKNDFGSFDAFKEEFTKVASSVFGSGWAWLVLDSGKLSITESSNQDTPLSQGLKPVLTIDVWEHAYYLKYQNRRADYIDAFFKVINWEQVHNNFKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V7Y4</accession>
    <name>A0A832V7Y4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="120" mass="13360" checksum="72E2C013049AA29F" modified="2021-09-29" version="1">MSSNTEDPCEDFTVSMIAGGGNIPAVSGQPCEWREFDGSIDGGWSHFKFEIRFLDSAESIRWQAGNEPRQSNEVSEIIQYLPIISGNNQNVNRIKLTLHTWDSNSDRATRQNVARSGGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8C3</accession>
    <name>A0A832V8C3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="152"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="287" mass="31638" checksum="C264DFA5934F93AD" modified="2021-09-29" version="1">MYWYVLAIISAFFEALYYTLIKKLVRKEDIRVIASGVFLTGAVILFSASLVRGIPEIGTQFYSSVFVTGILNVFAVVLYFRALKKTDISLSLPMLSFTPLFLIVTSFLILGELPSYVGGMGILLIVSGSYVINMSTDHKELFYPIQQILRNKGVLDMLGVAFIFSISANYNKIAVLNSDPILSSAGIFLVTAVPFLVYAKTTGENIIRSHKKVWGWVLATGLVISLTAVLINIALTMQIVPYVISLKRLAVLFAVIFGGVIFHEKHIARRLIGTLIMLAGAIIIVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8K7</accession>
    <name>A0A832V8K7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_02185</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="228" mass="25127" checksum="1297E48C27C56B9A" modified="2021-09-29" version="1">MAEIMFKAEDVWKTYIMGDTKTHALAGASLEVKKGEYVSIIGQSGSGKSTLMHMLGCLDSPTSGKVFVEGRDVSKLSSNELARIRRVKLGFVFQSYNLVSGLTALENVSLPQRFEGATKEKAEKEAAKNLKALGLEDRMLHKPTELSGGQQQRVAIARALVNDPDAILADEPTGNLDSKTSREIVDLLNHLNSKKKKTLITITHDKNIAEDADRKIYIKDGKIQKSWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8T4</accession>
    <name>A0A832V8T4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="4">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">ftsY</name>
        <name evidence="7" type="ORF">H1011_02735</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
            <orientation evidence="4">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="6">
        <location>
            <begin position="338"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="40"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="177"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="259"/>
            <end position="263"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="317"/>
            <end position="320"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="365" mass="40468" checksum="71654446419A110F" modified="2021-09-29" version="1">MFGNLKKKLKSFFDKAGKEAETEEVEEEVLVEVEEDLEAPKVTSKKKPKEKKEAEKEELEEEKKIEDSKTEKPKRKRSIFKKITRRHISEKSLDSILWELELALLENDVAKEVTESITKDTKERLLETDLKKGETAEKAITSALKAAIEKTLDVGDFDIIEKIREKEEGPTLILFVGFNGSGKTMTIGKFAQVLQNEGISVVMAAGDTFRAAAIEQLDVHAKALKVPIVKQQRGSDAAAVIYDAVEHAKAKGIDVVLGDTAGRSHADLNLMDELKKVVRVNKPDITIFVGDSLTGNDAAEQAKRFNEAVGIDASVLTKADCDVKGGACISISHMTEKPIIYLGTGQGYEDIEEFNPDWFVEKVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8Z2</accession>
    <name>A0A832V8Z2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleotide pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside-triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009143">
        <property type="term" value="P:nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11537">
        <property type="entry name" value="NTP-PPase_RS21-C6_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025984">
        <property type="entry name" value="DCTPP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12643">
        <property type="entry name" value="MazG-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029826">
        <property type="entry name" value="UCP029826_pph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="116" mass="13230" checksum="3D1FB99BB8D16B5B" modified="2021-09-29" version="1">MGDWQELKNKVDEFIKVRDWGQFHNPKDIAVSISIEAAELLENFQWVRSDDVEAHLGNGKLAEVKDELADVVIYCLSMASALDVDLEALVLEKLRKNGEKYPVDKSKGSYKKYTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X4X7</accession>
    <name>A0A832X4X7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S1 RNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="PTHR10602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="SSF110993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="SSF116742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="14"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="262" mass="29470" checksum="9EC964D0EC7C0358" modified="2021-09-29" version="1">MENKTRAQKFPEEGEFVMGTVSKIFPYGVFVKLTDYNGVEGMVHVSEVSNKWVKNIKDHVKDKQVVIVKVLKVVPGRGHVDLSIKSVKDIHRKKILDSHKRKQRVERILAMSEKNVKKESVEEVMDALEDGYEEAYSALEKILSEGEKALDGIELSDKWKKELVKISNDNIELPVVSIKAILELESDEGNGIETIRTAVKKARAANDDKEVSLELKYKGAPHYSIRLIGPDYKKIEKVLEKISAAAIDEMEGKGGSGQLIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X4Z1</accession>
    <name>A0A832X4Z1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">30S ribosomal protein S2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_00785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005707">
        <property type="entry name" value="Ribosomal_S2_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11489">
        <property type="entry name" value="PTHR11489"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01012">
        <property type="entry name" value="uS2_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="216" mass="23776" checksum="5ACAAAD65B92D178" modified="2021-09-29" version="1">MEEETQTISDGNLVPLDKYLAAGVHIGTQRKMKDMLPYIYKVRPDGLSILDIGLIDKKLGEAADYISKHPSAKVVVVCARDAGKKAADKFAEVTGAHAYTKRYMPGTFTNPEYKGFREPTLLIAVDPAGDRQAITEARSNNVPVLALCDTNNMTENIDFVLPVNNKGKKSLALVFWVLAREVLKKQGKLKSAEAFKVPLEDFEDTSEPQPEVVPKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X520</accession>
    <name>A0A832X520_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="42"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="213" mass="24427" checksum="1FEFC4DD250E55BE" modified="2021-09-29" version="1">MAEKQKLEEQLLSPDYLESDEWKLIKNVEDYSKDRLNTVAHGFDHTQRVFQNSLIIGLTEHADLLTLLTAALLHDVGRDIEIAIGADHADASAHEAKDFLKSVNFPAPKIKRVFEAIHGHRSSREGDQGFLESRILSDADKIDSLGAIGIARVFTFGGKINRDVQETITYFKKRLDKVMEQLHTDRGKRMAEERYNYCIDYLKRIENERTNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X526</accession>
    <name>A0A832X526_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="24"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="164"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="262" mass="29142" checksum="CEE776DC5661A014" modified="2021-09-29" version="1">MGLLDKFKKKKEDLIDDELMKDLGVPDLPLAPKPPKPSQTIAPKPRVAPIPKIPAKLPAPISRPSPTKPAQLSEKQVAKLPLFMKVENYQKVVGELKTLVDSLNNIGTTLNEMSNLEHEHEEALGRWRQQLDITKDQVHKLLSDMPETGRLKALVSAKTKTKSQEKIKKELTDLKKGMSEEEKKDSTIVQKEIKDMRSGITSLHDEMNRLHLELKTLNNLTQLSSSQVVGGIKEKAKAATPANIPLPSSRKPSLKKSKAKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X531</accession>
    <name>A0A832X531_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Elongation factor 1-beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ef1B</name>
        <name evidence="5" type="ORF">H1011_01410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the EF-1-beta/EF-1-delta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036219">
        <property type="entry name" value="eEF-1beta-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014038">
        <property type="entry name" value="EF1B_bsu/dsu_GNE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00736">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00888">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54984">
        <property type="entry name" value="SSF54984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF1_GNE" evidence="4">
        <location>
            <begin position="3"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="86" mass="9705" checksum="F63FE2F5477C15F1" modified="2021-09-29" version="1">MGKAALIYSIRPDGPDVDMKKLEEDIRKVPYFETLEKKPFIYGMDQIIATFILDDKDPKSDPDSIEKTLSETKGVSSIEQLALTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X574</accession>
    <name>A0A832X574_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="82" mass="9124" checksum="106EA3F9D7A3029C" modified="2021-09-29" version="1">MKQKTKFMLVATLVIMLVLSAAIEARSSRTADAPAKTDSGGVSGQFLQSFTCIFTQCGWPAIIILILPVFGMWVYKKYFSLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5D9</accession>
    <name>A0A832X5D9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="142" mass="17639" checksum="78FD91E713013F5B" modified="2021-09-29" version="1">MNLKKENEESLRKAFEKDPSVQNTYELVRFYFKEKNNESYTKSEKVVEDYVDSLEFSREQWWYEVVDEWWYSVKIFELRGIMRWRKEQYALSRRAYINALKIFNKNGYNKESRKLLGPRWLCARRLKKGLRRADMKIPRYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5E8</accession>
    <name>A0A832X5E8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="242" mass="26344" checksum="BC78397E374CC678" modified="2021-09-29" version="1">MSIGGRIMASQLTIGIVIAAALADSINPCVFGVLIFLMGYMLTAFKSKARLLIGGLIYIATVYVTYFLIGLGILSAAYSANLTNSLYMVAAVIAILAGILEVKDFFWYGKGPSLQIMPGGAERIKKYTYKFSKFNDKHPAFNMVLAVGLGVLVVFVELPCTGAPYLAIIGLLASGEYSNGVPLLLFYNLIFILPLLVILGLVYTGKASKQLEAWRKKHRGLMRLFIGIFLLALGTYMFWLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFN7</accession>
    <name>A0A832XFN7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000005">
        <property type="protein sequence ID" value="HIJ99348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="127"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="510" mass="56859" checksum="147FFDEE4266B571" modified="2021-09-29" version="1">MRAYYWVGIVIVVGYFINGFLTGQFSLHPFWRATMTDVMKLIIYILMYSFVFDYLSKGGEKGVPEFRLMVGTFYGALIIGTLFVDGDQAELIMIGVVLLVFVMRQGRKLMEERYGDKLKRFWADDIPKELEERIEHLKKVKKELEQRKEEIKEAGKMTIDLAEIRAAASTTGTTATNTFEVKNVSEEMLKMITKKDPTGKDFDIASLGAEALDGLIDKIEDFLKRYGTGKRRDLTARLSKESGGGDETIITEIYEEALIASQRLYLVASQLRGRGISPKIKTAKVRTSIITGEDDDRKAISVARHGQVYKLFTGESDVMKKLSDSLTLVNGAVQTVSAISENARISENGIGKDLEYNNWDIVDDAHIEYACGVKGWNLSGLGGAGPNNPLENDSYTQAAEKLNNIIMDGDTSFKERLDDRDLEVLDFNEACDGSSSDATHRRIPRQLLRWESSCALDDAHHRNFCNSEGADGHLGGTQGENENGRIYAIGETTTTGGQDWSDEVLTVRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFP2</accession>
    <name>A0A832XFP2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000006">
        <property type="protein sequence ID" value="HIJ99363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="178" mass="19802" checksum="045B93704F8C46B6" modified="2021-09-29" version="1" fragment="single">MRRGFFRNKKAVEEPTTADIMAVVGTIVIAVSIVVVFSVNIPSSIESAEVVLEEAETGAAARMMMSTILSSYDENLDMTGAQIISRMGADRQWAQAVGLDEIDEIVPLARVGDFCLLRPSSELYEDYIVDYDIDELTFTTGALQFPPDYFERIQSSDLSWWQGICMSSNTEDPCEDFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFQ4</accession>
    <name>A0A832XFQ4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043998">
        <property type="entry name" value="Put_Metallopep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18894">
        <property type="entry name" value="PhageMetallopep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhageMetallopep" evidence="1">
        <location>
            <begin position="4"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="115" mass="13752" checksum="ED7D0ED1BED52FE3" modified="2021-09-29" version="1">MVIKYEPAPDVKMRLVELITENGFSNVDPSKIYCFRSRGSKSKRILARIWSFPKIWQMALFMPPRYVIEVLSERYDKLSKEKQDYVLIHELKHIPKKFSGGLRTHHRENPKHLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFU8</accession>
    <name>A0A832XFU8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="255" mass="27809" checksum="B561D8669C1CE037" modified="2021-09-29" version="1">MKKFSLKGKTAAVFGGLGLIGKEIASALGQAGAKVLLIDIDEEKGHKIASELGAEFIELDITDIESYDEKISAIWKEQGQIDIVVNTAYPRTEDWSDKFEDVKSESWRKNVDMQMNSYCLLTIKFAELMKKNEIKGSIINLGSTYGVLGADFEIYKGTELSCPPAYAAIKGGIINFSRHAASYYGKYGIRVNALCPGGIFDNQNPEFVKAYESKTSLKRMGDPEEIASAAVFLASDASSYVTGTAFMVDGGWTSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFW3</accession>
    <name>A0A832XFW3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit Rpo1N</fullName>
            <ecNumber evidence="8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">DNA-directed RNA polymerase subunit A'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpo1N</name>
        <name evidence="8" type="synonym">rpoA1</name>
        <name evidence="11" type="ORF">H1011_01890</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.</text>
    </comment>
    <comment type="function">
        <text evidence="9">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8 9">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds at least 2 Zn(2+) per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the RNA polymerase complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="8"/>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00863">
        <property type="entry name" value="RNApol_arch_Rpo1N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012758">
        <property type="entry name" value="RPO1N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02390">
        <property type="entry name" value="RNA_pol_rpoA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 8 9" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 9" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="10">
        <location>
            <begin position="204"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="453"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="457"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="853" mass="96162" checksum="FCAAE3B10DD5A7A3" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHD6</accession>
    <name>A0A832XHD6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pyruvate, water dikinase</fullName>
            <ecNumber evidence="6">2.7.9.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Pyruvate, water dikinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">ppsA</name>
        <name evidence="13" type="ORF">H1011_00640</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:11364"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.2" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01418">
        <property type="entry name" value="PEP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="11">
        <location>
            <begin position="22"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="10">
        <location>
            <begin position="396"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="12">
        <location>
            <begin position="495"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="336"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="791"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="350"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="791"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="808"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="838"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="HIJ99315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="855" mass="94384" checksum="ECD9AB4EF6E5A51F" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHE4</accession>
    <name>A0A832XHE4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNase J family beta-CASP ribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_00790</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004613">
        <property type="entry name" value="RNase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00649">
        <property type="entry name" value="MG423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="8">
        <location>
            <begin position="15"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="445" mass="49584" checksum="674A58E4472FF653" modified="2021-09-29" version="1">MAIDIFAIGGYEEVGMNMTAVKIDEKVFILDMGIALDRMVLLQESGLPINKKTLLEARAIPDDSILNDFKGKVEAIILSHAHLDHIGAVGYLAAKYNAPVIGTPFTIELLKSNIKDDKLNFNNFVVMNAGEELEFGDVTLEFIHSTHSVPQTVFPVLHTKYGAVFYGIDYKLDNKQKLSAPPDYKRIRQIGKEGVHALIVEAIRAGEKGKTPSESVALEMLRDTLRDNFASKNAIVIACFSSHIERLNTIVEASKGMRRKVVFLGRSIGKYTDVSKKINFKSFPNVEIAGHQRAVRAILKKIARDRSKYIIVCTGGQGEPNAILSRIARKEYALTVEPGDKIMFSCITIPTPVNIRNRKSLEDLLSSQGARIFRDVHVSGHSAREDHREFLHMVQPEHIIPCHGDIEKLTAFGTLAEEINKELGHDKYIIGKNVHLLKNGRKISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHM3</accession>
    <name>A0A832XHM3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YIP1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="190" mass="21971" checksum="AB91866E551CAF52" modified="2021-09-29" version="1">MARKKIDLGEHFSKHLHDILLYPKAAIRHILKEDSNTMGLWVPAFVVVGAAILTSLGGAIWSIIITDSTLIGLMEVAKFYLSFVVLPFWYLSLWIVWALVIHFMASVYTGKDITNWDVFYRTMKVVGIAWAPLFLNILPFFVRITWFWWIYLVFWGVKYNYGASKKIAFIVIFPALFIEVLKLYTLLASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHN5</accession>
    <name>A0A832XHN5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">VRR-NUC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_02525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014883">
        <property type="entry name" value="VRR_NUC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08774">
        <property type="entry name" value="VRR_NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VRR-NUC" evidence="4">
        <location>
            <begin position="56"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="169" mass="19561" checksum="C0A5F40DD9D0D243" modified="2021-09-29" version="1">MPFYFIPHSRNFSSKRGFAESSLRRRLEKQGWSVWKGLLIGAVRMQDDYSTATGKYELLSKFLEKHSAELLEKLQYYCSVHFGFPDFICHKNGEWKFVECKLGYEPLSEKQKKCIMELQLLGFNVEVHKLVSSPAGTRSAMVNLEGSGKIVTRKQLTLNNRLFIKCQNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHP8</accession>
    <name>A0A832XHP8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_02760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016668">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="3"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="301" mass="32591" checksum="2066CB200B57D958" modified="2021-09-29" version="1">MHDCIVIGGGAAGLGAALYAARFSLDTILIAPDMGGTGNIAHKVDNWIGDPGITGIDLMQKFIKHVKEYKVPMINETVTKIEKTSEGFKVTTNKSEYAGKTVIYSTGMKHRKLGIPGEDELQGKGVSYCYTCDAHFFKDKVVGVVGGGDSAGLGTLLLSTIAKKVYVLYRGDRIRAEPIITKEVYELENENVKVMHNINVTEVLGEKTITGVKLDNGEELALGGLFIEIGANPINELVKELNVELDERGFIKVDKTMTTNVDGFYAAGDITNNSTLKQFITSASEGSVAAQTIYKYLRGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHQ6</accession>
    <name>A0A832XHQ6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="145" mass="15914" checksum="AF71DF520D5A374F" modified="2021-09-29" version="1">MAIVRTRLTKILASVNKSKKATSSSIEISNKNSIESVKKEKIKGIGDVIEVEFSLETQYEPNIGNIEIEGTIVYHDKDLKKQIEEKDGKIVLLEDAFLEVNNTILAIGSVQSLLMAKEMNLPSPIQLPMVEASKKPKGKGGKGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIH3</accession>
    <name>A0A832XIH3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Type II secretion system F family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_00320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="126"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="293" mass="32802" checksum="A017BBB285696FD1" modified="2021-09-29" version="1">MAEKQSSYEKYVEVASRLFRDFVETKIDKFRWVHPFLRQANMGIMLREYICLCFLNALITPAIALPITYLYIILLGKPFLLALVLSLAVTAVLTAGIFVGSLYYPKMVAAERKKDIENNLPFATLYMNTIAGTGAPPFAMFKLLADFKEYGEVSKEAQKIVEDVEVMGRDIDAALHKAAEQTPSDQFKEMLLGISTTIVGGGNLRVLLSGKSKILMNEYRRKIEKYTNELSIYIELYITLVIVGSIFSTVMLTIMGSISGFESFRFLQQALVYIFLPVAGIVMIGLLKIASPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIH4</accession>
    <name>A0A832XIH4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5679 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044044">
        <property type="entry name" value="DUF5679"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18930">
        <property type="entry name" value="DUF5679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5679" evidence="1">
        <location>
            <begin position="8"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="50" mass="5402" checksum="354B6D2AC2FFB526" modified="2021-09-29" version="1">MADYKGRCMKCQKEVDITGAKVVTTKNNRKMAKGTCGSGCGTTVCRFLPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIK2</accession>
    <name>A0A832XIK2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="185" mass="19881" checksum="DEAD43BC0B4094E1" modified="2021-09-29" version="1">MPEKIQVKVPNSWIHFSKAGVSILIMLLLIRLGFGVAWSTLLTILAYIAAGMLSRLPVRYGGSPVAGIELATTLTIITSIQYGPMAGSIVGAFSYGLPIMYTRESPSDVFVGTLGYIVIGLFAGGLYGMLGNLAMTALVIVILYDLIENLIYLTLGHTLIGCIKFSVIHIPAVYLITKYLGIILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIP7</accession>
    <name>A0A832XIP7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ahcY</name>
        <name evidence="8" type="ORF">H1011_01800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 6">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000010">
        <property type="protein sequence ID" value="HIJ99541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="7">
        <location>
            <begin position="183"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="149"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="212"/>
            <end position="217"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="416" mass="45554" checksum="969C6C46D258592F" modified="2021-09-29" version="1">MSKIADEKLAAQGRKKIEWAESRMPVLMSLREKYGKSKPLKAQRIAGCLHVTKETAVLIETLKEAGAEVSWSGCNPLSTQDDVAAALAEEGTDIYAWHGLSNEEFYWCIEQTLNFKPTLTLDDGADLIFTIHKKHPELAKEIIGGTEETTTGVHRLRAMGEEGKLLYPVIAVNDAETKWDFDNVYGTGQSTLDGIMRSTSVLFAGKTVVIAGYGHCGRGLALRASGLGANVIATEVNPIAALKATLEGHRVMKMDDAAKLGDIFITATGMKDVIIGRHFESMKDGAIVCNTGHYDLEINLNDLESLAKTKREVRANNEEYVLKNGNRIYLLAKGRLVNLAAAEGHPSEVMDMSFANQFMSMISLVENKGSLENKVHDIYAEQDCDIATLKLKTMGFSLDKLTAEQVKYLTDYAAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIQ0</accession>
    <name>A0A832XIQ0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">NusA-like transcription termination signal-binding factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_01880</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010212">
        <property type="entry name" value="NusA_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01952">
        <property type="entry name" value="nusA_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="KH_5" evidence="7">
        <location>
            <begin position="35"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="6">
        <location>
            <begin position="86"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="135" mass="15036" checksum="7C79F3D773382C74" modified="2021-09-29" version="1">MTLLITNDTLALVSALEKISNARVIECIDSEKELIYIVQEGDARLAIGKNGENAKRLSRDAGKNVQIVEISEDPVKFVKNYIGNRMDYSVELKESSIIITTDDYNKGRIIGKGGTKVKILGSLLKRHYNLQVKVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIU4</accession>
    <name>A0A832XIU4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exodeoxyribonuclease III</fullName>
            <ecNumber evidence="4">3.1.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">xth</name>
        <name evidence="4" type="ORF">H1011_02765</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.2" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020848">
        <property type="entry name" value="AP_endonuclease_F1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="PTHR22748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00728">
        <property type="entry name" value="AP_NUCLEASE_F1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="251" mass="28721" checksum="77BABF55B292C62D" modified="2021-09-29" version="1">MKLLSWNVNGIRASLKKGFLDFVEKENPDILCLQETKAHPDQVDEILDDYHKFWNSAEKKGYSGTAVFSKEEPLSVTNGIGIEKHDKEGRVVSCEFDDYFLVNVYTPNAQNELARIDYRIDWDKAFLNFIKTLEKSKPVITCGDLNVAHKAIDLARPKQNEGNAGYSEQERAGFDAYINAGFVDSFRIFNQEPENYSWWSYRAIGARDRNVGWRIDYFLVSESLKDKVKTAFILNKVMGSDHCPVGIELKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIU7</accession>
    <name>A0A832XIU7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="182" mass="20549" checksum="48C66ED5DE175BEC" modified="2021-09-29" version="1">MLRPDLEELGRFYKRLGEQGFERGKPWFYISGALTGVSNIDDMKKFYEELSDVIMNHGGFAYVPHRITDPVENPDVSPMEVYEVDMKSVINCRRKGAMVTVLEHPSLGVGAEIQKSFSSGVKMIYLAPAGKGISRLIMGGGEALRGVSEDIFVIEYKNHKDALKKFSEHLDEHFSVERGYRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL17</accession>
    <name>A0A832XL17_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA replication complex GINS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036224">
        <property type="entry name" value="GINS_bundle-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158573">
        <property type="entry name" value="SSF158573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="192" mass="22260" checksum="597595E80A68F5EB" modified="2021-09-29" version="1">MTEVIITYETLREIQRDEKRSSKLYSLDENFYSIVQDYLGRDLPADDISRNEILNARKILEDIQDRREKKIINYALAIARNNEKFDVSELTTEEHLLLENLVETLKKYRSNIDKASPSEAKKMTETVEEPVEEEKIPEDIEKALIKIKILKDLPQIVGADMEEYGPYSAGEIAEIPEENAKILIENKTAEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL59</accession>
    <name>A0A832XL59_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="171" mass="19595" checksum="419FD690CD9617B7" modified="2021-09-29" version="1">MEIEVIQNRKKWASLMDELEPKRLKDPDEGVDFTVNKKGAVHCLFSATCLLIMMSGKKSAVAHIDTFFLRGSDRKRNIREAARIFEDLEKAFGSRRNVEIAILSGSEEIRQLVKESFPNKFTVEYCEKFPRGILSHPMKRAIADPESEKIFIFVSDQDRLGSIITKSSVWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL65</accession>
    <name>A0A832XL65_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="HTH iclR-type" evidence="2">
        <location>
            <begin position="258"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="317" mass="34649" checksum="D4638333F3D63424" modified="2021-09-29" version="1">MKTSVKVIVFALFSALLMAQTVSAYDVVVAGEDYPVDFFLAQTYTSKEGILLIGVSKKGFTQPIASELLGYAQQGYTEAVIIGGIEAVPESVERSLIAMNYSVIRIWDWNRYGTAARLAVTLWEESETVIIAEGDIQGAVMPAARIAIDYGSPVLLTERGGLSESAEQAIKKLGARRIVVVGDLSDEAMKKLDSLGGVEQTKLTQSPLVETGGKSSFLVGLIAGGLIIFLITSLWGAEIIRKKENEIPYDILQDDERRIVELVESQGGRMKQQDVDEMTGFSRPKVSRLISELVERGILSKRKSGKTNILELIKKMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL93</accession>
    <name>A0A832XL93_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="222" mass="24834" checksum="D614B3CB793A1149" modified="2021-09-29" version="1">MSDPIMLGTEKEYADCVLRLIDESSSFIDDIRSRKIKFLTASSRCRIDELIESADSCEMQKVRSIAPSLQALNGDLSILLKKFQIIKSAYRTDETLKSFLGDYTQNPSNSCSKLINFIDSSITQMDSVIAKYSDVDRAKKPAHTWIMTVLSNHSGDSVYKKARKARLVLESIRNLIGELQGVCHSSKLELLNIRNTASKNLSKAGRLTYKSPFDNNQEKGAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL97</accession>
    <name>A0A832XL97_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribulose-bisphosphate carboxylase large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016984">
        <property type="term" value="F:ribulose-bisphosphate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033966">
        <property type="entry name" value="RuBisCO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000685">
        <property type="entry name" value="RuBisCO_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036376">
        <property type="entry name" value="RuBisCO_lsu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017443">
        <property type="entry name" value="RuBisCO_lsu_fd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036422">
        <property type="entry name" value="RuBisCO_lsu_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42704">
        <property type="entry name" value="PTHR42704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00016">
        <property type="entry name" value="RuBisCO_large"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02788">
        <property type="entry name" value="RuBisCO_large_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00014">
        <property type="entry name" value="RuBisCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51649">
        <property type="entry name" value="SSF51649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54966">
        <property type="entry name" value="SSF54966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RuBisCO_large_N" evidence="2">
        <location>
            <begin position="45"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="RuBisCO_large" evidence="1">
        <location>
            <begin position="150"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="466" mass="51427" checksum="F2E235C685661967" modified="2021-09-29" version="1">MAVQFNYLAPKGWKPKNAEENYLITLLKMELSKEAIKEAGKTSKKIIFEEAAASVAAESSTGTWTKVYDGPGSGIPLAREKRALAYDLDYKNLMFKVAYPVELFEPDNISGLLAGIVGNIAGMKMVSAMRFYDVRFPRKMVEVFLGPKFGVHGIRKLLKKPKGPIVATVPKPKIGRTSSEQAALAWELFTSGHGTYDGIKDDENLTSLEFNKFDDRAKKVLAKLKDAELRTGKKKFYLANITHSNIGIMETRAETIKKNGGIYMMIDVVTTGFSAVDTMRRKETGLAIHAHRAMHGFITRDNSPGVHGKGKLFGFSISMIVLAKIFRLLGVDSLHGGSPLAKMEDYGEAEYIKQVLQDTETQEHEKIPSLGQKWHHIKPVWMVASGGLHPGDFEAVIRTLGEDIMLQCGGGLLGHPGGVEAGVMAIEQAREIAMQGIPIREWVKKNPDSELAEAVKFWGYGPKIVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLF3</accession>
    <name>A0A832XLF3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription elongation factor Spt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">spt4</name>
        <name evidence="4" type="ORF">H1011_03280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Stimulates transcription elongation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer composed of Spt4 and Spt5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal Spt4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00949">
        <property type="entry name" value="Spt4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022800">
        <property type="entry name" value="Spt4/RpoE2_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007178">
        <property type="entry name" value="Spt4_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038589">
        <property type="entry name" value="Spt4_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40704">
        <property type="entry name" value="PTHR40704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06093">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01389">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="SSF63393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Spt4" evidence="3">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="60" mass="6540" checksum="21B6C5C3D146C0DE" modified="2021-09-29" version="1">MSKACKNCSRLNESNVCVSCGATDFSSRWSGMVIIINPEKSIVAEKLAIKEKGEYALTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLF7</accession>
    <name>A0A832XLF7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Translation initiation factor 1A</fullName>
            <shortName evidence="1">aIF-1A</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">eif1a</name>
        <name evidence="5" type="ORF">H1011_03360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05793">
        <property type="entry name" value="S1_IF1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00216">
        <property type="entry name" value="aIF_1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001253">
        <property type="entry name" value="TIF_eIF-1A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21668">
        <property type="entry name" value="PTHR21668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00652">
        <property type="entry name" value="eIF1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="1 2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="19"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="103"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="105"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="162" mass="18672" checksum="C4354E489D5764F6" modified="2021-09-29" version="1">MAYYKKRKKHGSFDPNAPVRVRMPRKENREVLGIIIEHYGTKLLVECMDGYTRLCRVPGKIRYKLRVKPGDVILVQKWPVQENEKGDYLYKYRPNQVNILRRKGLLTTESEEAEQSEEKSETPPELPEKEAENKSEEATKEKGDTADGSEKTESEGENSVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULC5</accession>
    <name>A0A832ULC5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipoate--protein ligase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="28"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="248" mass="28067" checksum="0C679A77EAB0157E" modified="2021-09-29" version="1">MRLIKLREEDGAMAMAVDEAILKARSKGLVPDTCRLFVFKPSTVTIGYFQSYAEEIYDENRRKVGIDAVRRITGGGAVYHDQQGEITYSIVMGEDTLNKKIPESYGFLCQPIIEALDILGIKSEFKPINDILTNGKKISGSAQTRKWGAVLQHGTLMYNTNIDELFSVLNVSKAKIADKILDSIKDRVTTVKQEIGDISRKEVEKAMIEGYRRVFGELEEEELTAEELEMAEELRESKYATDEWLNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULS4</accession>
    <name>A0A832ULS4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000010">
        <property type="protein sequence ID" value="HIJ99533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="330" mass="36099" checksum="17E3E1891A3043BF" modified="2021-09-29" version="1">MNKNRKALIGVAAIAGAVIVIVVATSVFIEAEQAEEITTQQAQSIVSQNPGEVFEVIREVMDECVSEALFFANFEDIGDPRAYEDFLNVICSESLLELEYFITSKGFSQNITFVVDTALQEVMSINVSAQLSSAAGRISQDFVSSDAVYVCVPQTEAVDLECITDSANLKDFNKSPLNPTTDCELHFTILDESLNYLQMPVMIGFGDTLPPIGGVPGTPYTVRFITAEDPLATVKVEDYRLSLCRLDANFSSTGEILDLTLDTSTCLVREVVVSPLGPVCEDCAQCESVNPHYYRFLSLNLAIEHPEDFSVSHCRIENLTDCFPVLGVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULX8</accession>
    <name>A0A832ULX8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_02250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="70"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="237" mass="25739" checksum="23EEA45C7577AAFD" modified="2021-09-29" version="1">MIYAEILASLFILIGLAYLFVVIVLSFKERKKVAWLVILNIAIFTYISFSDPRLMYEYMLSGTAISSNAGYALVTYMFLHANFTHLFLNSIALLFFGYHVEREFGAGQMIFVYLTSGLIAGGFFILTSSPNASVVGASGAIFGLMAYLTLLRPFKISPMPFLIPLPIALAAVLYTVATIPLFLSGNISGGISHSAHIGGLLGGSIMAFGLNYIEARRGLLIVLAILILILMMPVVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULZ6</accession>
    <name>A0A832ULZ6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="2">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="2">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="2">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="2">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="2" type="primary">folD</name>
        <name evidence="5" type="ORF">H1011_02415</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="2"/>
    <dbReference type="EC" id="3.5.4.9" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="1 2" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="3">
        <location>
            <begin position="6"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="4">
        <location>
            <begin position="120"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="162"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="276" mass="28889" checksum="B88A843F15BCDB28" modified="2021-09-29" version="1">MPAQLIDGQQIAKDKYIALQLAIDKLDFQPGIATIVTEDNAASKLYASKRGEIAKSIGMYSEVHDLGGSSKDEDIIRLISDLNKDVKIHGIIVQMPLPKNSDITAILGSLNPKKDADGMHPSNLGNLFLGTPLIIPAASKAILELINSTGISLPGTKVTVIGNGLASGKPTAILLQNKGAVVTVCNSKTKNLKSHTLDADIVIASVGKAKILTEDMIKEGAIIIDAGINIIDGKLVGDIDFKGVSKKAAYITQVPGGLGPVTSASLLENVIFLATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UM05</accession>
    <name>A0A832UM05_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fe-S cluster assembly ATPase SufC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sufC</name>
        <name evidence="5" type="ORF">H1011_02490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="9"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="250" mass="27395" checksum="02C6698287C615C4" modified="2021-09-29" version="1">MADLSKDKLVVKNLEVSVDNEKILKGVNLEIGKGEVVALMGPNGSGKSTLANVIMGNPNYKVDSGEVTYKGKNILELSPDKRSKLGIFLSFQYPSAITGVTVANFLRTAMQSRLGKNEKIDILKFYDEIKEKADELNIDEAFLSRYLNDGFSGGEKKITEILQMAVLKPEIAILDETDSGLDVDALKAVASGINKIRSDNMGVLIITHYQRILNYIKPDRVIVMSKGKIVKAGGPELAEEIEEKGYEGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UM61</accession>
    <name>A0A832UM61_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="80" mass="9291" checksum="CC3F650AC208652C" modified="2021-09-29" version="1">MKTKGYSDQTEKQWLILGTVFVVLVFSLHFFTVLPTSFEAESAEDALFVSENCPAYERFFYEKNDIERQESETNNIPQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPE9</accession>
    <name>A0A832UPE9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Signal peptidase I</fullName>
            <ecNumber evidence="5">3.4.21.89</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_00620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="5"/>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001733">
        <property type="entry name" value="Peptidase_S26B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027245">
        <property type="entry name" value="Sec11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806">
        <property type="entry name" value="PTHR10806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10806:SF6">
        <property type="entry name" value="PTHR10806:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02228">
        <property type="entry name" value="sigpep_I_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="171" mass="19074" checksum="54A4848B4F75EB31" modified="2021-09-29" version="1">MDRKEIAETILYLFFGFVIALIGHSALGYALDTEYPVVSVVSESMEHDDPETYSGWFIDRNFDETELGNWPFSGGMNKGDLVLVKGSVVSELNAGDVIVYKIGGGKPIIHRIVWINDSKVYTKGDNNKNTDQEGVHLTPPVQDQHVQGRAVFRIPLLGWIKIAFMNIVGFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPL4</accession>
    <name>A0A832UPL4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">DNA polymerase II small subunit</fullName>
            <shortName evidence="12">Pol II</shortName>
            <ecNumber evidence="12">2.7.7.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Exodeoxyribonuclease small subunit</fullName>
            <ecNumber evidence="12">3.1.11.1</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">polB</name>
        <name evidence="14" type="ORF">H1011_01160</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 12">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 12">Heterodimer of a large subunit and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the DNA polymerase delta/II small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="12"/>
    <dbReference type="EC" id="3.1.11.1" evidence="12"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000738">
        <property type="term" value="P:DNA catabolic process, exonucleolytic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00325">
        <property type="entry name" value="DNApol_II_A_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024826">
        <property type="entry name" value="DNA_pol_delta/II_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011149">
        <property type="entry name" value="Pol2_small_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10416">
        <property type="entry name" value="PTHR10416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000803">
        <property type="entry name" value="Arc_Pol2_small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 12" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="12" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 12" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Metallophos" evidence="13">
        <location>
            <begin position="216"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00024817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="HIJ99416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="487" mass="54476" checksum="3E444EFF12241CEC" modified="2021-09-29" version="1">MNIQTQKDLLRLVLGKNLQITTDAIRLISEQSDPKKALENSIQKLEPQEFLLTTTHFTKTQSISEKKIGSLFKTEVSIIQNFTKTPYADNLQTISDFFRARYNHFKKVLSPRTNNTMSLAHAEKAKGEKCSLIGIVSDKRVTKNSVILELEDPTGVLKTITTSPEANTQAESIVLDEVVALEGSMGDDIFFTNNIIQPDLPTGKHMKKLSDSSYAAFLSDIHIGSKKFLRKEFKNLLDWFNSDVESNMQREITDNINYIFIAGDLVDGIGVYPNQKDGLYETDITKQYTEAAKLLSKIPENIEIIICPGNHDYTHLAQPQTPLTKDIAPELNELNNVTMVSNPSLVNIHTSDGGGLNTLLYHGTSIDTIVASDKTFKDGYKHPEIVMLALLKKRHLSPIYSSDLVTSGQDSMVIPSDIDIFHTGHVHSNGAMNYRGVTMLNSGTWQGKTDFQELCGHEPTPGNLPVINMKSREMQLINFYKNEPTRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQA1</accession>
    <name>A0A832UQA1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">infB</name>
        <name evidence="9" type="ORF">H1011_03250</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_A">
        <property type="entry name" value="IF_2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029459">
        <property type="entry name" value="EFTU-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004544">
        <property type="entry name" value="TF_aIF-2_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14578">
        <property type="entry name" value="GTP_EFTU_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00491">
        <property type="entry name" value="aIF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="2"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="73"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="127"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="583" mass="63994" checksum="85B99E4C22B0EA49" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQB5</accession>
    <name>A0A832UQB5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="6" type="ORF">H1011_03325</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="45"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="117"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="200" mass="22165" checksum="40A0DDFA4A7EB708" modified="2021-09-29" version="1">MNNIVEKIWEYGAILVSTDDGFDLASGKKSPIYIDCRSLISYPDVMDLIAKEASKIVKKTGVEILAGGETAGIPYAAWISARTNIPMAYIRRRPKGYGRTSQVEGSMDSGKKVLLVEDLITTGYSKESFVEGIRNTGATIEHCLVVFDREQGGRERLKENGIELHSLVTLSETLDYGLKTGELSQEDYEKIQKYLEDGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQC7</accession>
    <name>A0A832UQC7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonuclease P protein component 4</fullName>
            <shortName evidence="2">RNase P component 4</shortName>
            <ecNumber evidence="2">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Rpp21</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rnp4</name>
        <name evidence="3" type="ORF">H1011_03405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Consists of a catalytic RNA component and at least 4-5 protein subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eukaryotic/archaeal RNase P protein component 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00757">
        <property type="entry name" value="RNase_P_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016432">
        <property type="entry name" value="RNP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004878">
        <property type="entry name" value="RNase_P_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="108" mass="12632" checksum="B90943E284F2D509" modified="2021-09-29" version="1">MGKKKGKDRILASERITRLFSLSGKVFKESPELSNRYVKMARDLGMRFRVKIPKKYKKLYCKKCHSYLKPGISSRVRLSQKRQPKLVISCLACGNIMRYPYSKEKEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQI0</accession>
    <name>A0A832UQI0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Threonylcarbamoyl-AMP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="181" mass="19934" checksum="D5AD2082DD715161" modified="2021-09-29" version="1">MNLDISESLSSLKSGGIIIYPTDTVYGLGADIHSETAVEKIHTLKERSSKEKPISILLKKEWIPDYTDLSELAEKRVEELLPGPYTLVLKKTDKVPVWIANQDYVGIRVIDTIVVNELLDKFSSPITTTSANLRGAPPPKSIEEIPDAIINSVDSIIDTGPIISKGPSTVIKINEKEEVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UT38</accession>
    <name>A0A832UT38_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TIGR00270 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004451">
        <property type="entry name" value="CHP00270"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00270">
        <property type="entry name" value="TIGR00270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="67"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="120" mass="13515" checksum="42A356A46B3A4744" modified="2021-09-29" version="1">MECELCGLVLDTERKVSVGGSTVSVCEHCTRYGKEIFTRNVEASKIGQSNYKIPEEAFLVDDFGKMISQQRQKLEMTQKEFGVFLGVKLSELKMIENGKLRPDDTTVKKMGNKLGLSLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UT62</accession>
    <name>A0A832UT62_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004384">
        <property type="entry name" value="RNA_MeTrfase_TrmJ/LasT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42786">
        <property type="entry name" value="PTHR42786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004808">
        <property type="entry name" value="LasT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00050">
        <property type="entry name" value="rRNA_methyl_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="229" mass="25410" checksum="26D1E8466F5AE682" modified="2021-09-29" version="1">MVSVILLKPLYQGNIGSVARAMKNFGFSELVLVGSEIGEEARKMGMHSQDILDETKVFESLEDAVESFDLLVGTTSYETDKDNKFLKMNFTPAELKKKLSQVSGKTALLFGPEDSGLTNDELARCDMTVSIPTTGEYRSMNLSHAVAVLLYELSSLKGKRDVRIAGRKELDIMRKNIEEIANLAGHTEKEKIFNEMIGKIIGRSMITGREASTLIGFLKKVKGELRKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTL6</accession>
    <name>A0A832UTL6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="122" mass="13319" checksum="BBCFCB1F110CFB9D" modified="2021-09-29" version="1">MAKKRKEKGEKVDFFGILDVVDLFLELIPGKAATLMLIIGVIGGGYFGYQYGLAAAPECPEISCPEIICPEIVVCQEVEDCPPVEDCPTCPKDVTEYTCEELNDLLKPKCVCSTPIYTSSGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTN2</accession>
    <name>A0A832UTN2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
            <ecNumber evidence="3">5.3.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="3"/>
    <dbReference type="EMBL" id="DVAD01000011">
        <property type="protein sequence ID" value="HIJ99544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="286" mass="30891" checksum="D23DF3B3149D1BE3" modified="2021-09-29" version="1">MSVESVARDIREMKIQGAVTIAMAAEEALEEFIKNCQAGSRDDFLSQLRAEGNKLAEARPSAIALPNAVDMFIEKVEAINLGMPDLKDAALLAGKELMEDTKDSFKELTEKGSEIVRDGQLILIHCHSSTVTGILKKAWDSGKRFNVICTETRPSKQGFISAKELAEHEIPTTIVIDSAVASVMAGVDIALVGADTILKNGDVVNKIGTLGVALAAKEFGVPMYVATQRLKFDTKGKGVGIESRPAEEILEGAELPGVEIENLVFDITKKSYFKGIITEGGIRLKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UU01</accession>
    <name>A0A832UU01_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="128" mass="14097" checksum="5D1BBC0EAAA7232E" modified="2021-09-29" version="1">MSKKTILLAVSLIVIISGVLLFKPQVSGFISLGHDYTLDNFTECLAENNAIMYGAYWCPHCTTQKEMFGDSLSGVLYIECDSKGKNAKPELCRQNNVQSYPTWIISGTKYSGVQSLQDLSDITGCSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UU23</accession>
    <name>A0A832UU23_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="88" mass="9912" checksum="EB3CAA7918773F37" modified="2021-09-29" version="1">MRKSNTLPETFLFVSKVESKTGKDVVTCLRLTMEQAVAKRKALEGGEEDIFNTGDSFKSIRILPPGTAKVGDLVEYTREDWVPVDYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UU37</accession>
    <name>A0A832UU37_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="64" mass="6913" checksum="99B4496F1322AA56" modified="2021-09-29" version="1">MEAKTVEEITAIALSLVVFIHVIRAIMGIPVSIGSVEIPIWASIAAAGTVGYLAYLNWNAYKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UUF0</accession>
    <name>A0A832UUF0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000019">
        <property type="protein sequence ID" value="HIJ99904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="280"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="841" mass="92005" checksum="7977D3B3B7F084D0" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UXV0</accession>
    <name>A0A832UXV0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lrp/AsnC family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_00400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="164" mass="18421" checksum="139630768386227A" modified="2021-09-29" version="1">MVICAGTMTKLDDKDKKILHELQDNCRQSSRDLSKKLDLPASTIHQRIKKLEKSGVISGYTAIVNPEKVGYHSSAIIFIEYNHYEAKQNNLSQETLVEKISKLPNVQEAHMVTGLEDIVIKVVGKTDRDIGAFVIKTLREIPGILKTKTGIILASTKDSRRIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYC4</accession>
    <name>A0A832UYC4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetate--CoA ligase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="10"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="216" mass="23246" checksum="F0E45EB1188A6807" modified="2021-09-29" version="1">MRVLTEIQSKKLLKDHGIKTTKQIFAASPQEAASAASKLGFPLVMKIVSPDITHKTEVDGVRVDIKSIPEVIESYKSIISSARKARPKAVIEGVSVQEMADGVEIIIGVSRDSQFGPVIMIGTGGIFVEVLKDVSFRVAPISESDALEMISEIKGNILLKGVRGKKPSDIKSLVSMLLKMSKLAMSDESILEIDMNPVFVNPSGAMAADARVVLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYH4</accession>
    <name>A0A832UYH4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="204" mass="22190" checksum="3CEEA96641B653FA" modified="2021-09-29" version="1">MTGMLDNVLAAAILLIVGIIVGKVIGAAILELLKRFKIDSYVGIKREHLKVSKLISDISKWLIYLLFLSEAAAVLEIQIIANALTSLVNYLPNVLTAILVLTVGYVVARYIEDAIEDTHVAYSGLMSRVFFFFVVYLSAAISLNSLGSRIINTVLVDQILLIIVATFGVGLSIAMGLGFKSMFKSLGDEIGKDLVSGLRRKRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYL9</accession>
    <name>A0A832UYL9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">VIT1/CCC1 transporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_02515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:cellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="PTHR31851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="228" mass="24966" checksum="EE43CE5EA72AD7EE" modified="2021-09-29" version="1">MEEEHFIDEKKYLSDAVLGLNDGLISNLALVAGVAGAIAHSNIVLIAGIAEVLAGSISMMSSNYLSTKSDSELYDKELEREKQEIRDMPDVERQEIRDIYAKKGFKGKDLERVVEVITSDEEVWLRVMMEEELGFGKVSNKNPMKAAGYTGLAFVFGAIIPVIPFMIFSLSAQALPYAVAFTAAVLFAGGAAKSKFTLKKWYIGGFEMVAIGIFATALTYNLGLLFQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYW7</accession>
    <name>A0A832UYW7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="209" mass="23341" checksum="86A41410C494A51B" modified="2021-09-29" version="1">MVKQTQFFAFLKKRGSLGLVTAVFFLLAVYGLIASSNILFIVGLFTILSIYSRIYSCKAPLDISVIGIGSICIAVISDVWLAAIFGLSIWLVTMVWQPYIEFSYQIPHAIASFIVMFFFPIFISYAGKNLVLIAVSYGVAKFVIESMVFTPLLRPATIIPDLIFNLQELPFTIFYTALVMQFFAGPILLSLGIPGWETGSLWLFIKTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYX9</accession>
    <name>A0A832UYX9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dna2/Cas4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas_Cas4" evidence="1">
        <location>
            <begin position="32"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="228" mass="26680" checksum="EF69AF8CEF33081F" modified="2021-09-29" version="1">MIDFDELVDNYLKRESKKKTIGRYYPSEIGGCLRKIWYSYKFPEEEKDKDLIKIFALGDMIHDFVVKVLESDKNAHIDSIGVEIPFTREVEDFIISGRIDNLILFKEDSKKLLIEVKSIKNINSLDDAKPEHKMQLQLYMNSLDIKNGVVLYIDKQNLKSKVFPLAYDEEMANKIIGRFKALHASLVNDIIPIPEARIEDKTYICRFCEYEDRCYAETPKLEAQKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYY9</accession>
    <name>A0A832UYY9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">flpA</name>
        <name evidence="5" type="ORF">H1011_00525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006540">
        <property type="entry name" value="Nop17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="73"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="91"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="116"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="217" mass="24943" checksum="362175C29CEE7590" modified="2021-09-29" version="1">MKLLKKLGNDYATLSLVSGRKVYGERLKKIDGKEYRFWDSYRSKLSAALTLGLNNMHFEEDSTVLYLGAANGTTASHISDLVPKGIVYCVEFSPRAMADLYPLCKKRKNMVPILADANQPIQYAHRIGQVDIVYQDVAQRHQADILIKNAKMFLKPRGWTYLMVKARSIDVSENPNKLFNIIINQLRSTFDTEEKLKLDPYEKDHMCIVSRLRKTIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZ07</accession>
    <name>A0A832UZ07_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2085 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019206">
        <property type="entry name" value="DUF2085_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09858">
        <property type="entry name" value="DUF2085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="171" mass="19110" checksum="08ADB6C8C922D19B" modified="2021-09-29" version="1">MKLKKFMCHQRHERSFKFSKYLVVCSRCTGVYLGAFVSTILLLLWFGSFTAVSGLLLPLAFMAPLALDGLAQLVLGTESDNTRRFFTGYLAGASLAILFFSTLSRVLNPYTALIITFSTSRIIVASIPLFFIIKKFENKSAPWLEFTLNFIVIKSIIGFGLVSVYLLISLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZ08</accession>
    <name>A0A832UZ08_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="SSF47113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="166" mass="19170" checksum="0B35D26C648EFA2C" modified="2021-09-29" version="1">MAEENADEQAEEPTEEAVSEDAELEKELESEEEQERLPFPNARVVRLLKSELDPDKMVRARVKKELNEWLGELVRRIGREINKSPYTVVEAQDLHKATKKYDQLDEVAQQKERLISYMNRIKGDCNILIEDVEKSFDVGGNVRRGRKLSAAAQEEQDAQQAENEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZE5</accession>
    <name>A0A832UZE5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_01600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="3">
        <location>
            <begin position="6"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="4">
        <location>
            <begin position="107"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="303" mass="32928" checksum="4CE4D09987B3494F" modified="2021-09-29" version="1">MRSLKILAADPISEEAAKEIRDMGELELSPTISSEELLEKIADVEILIVRSRTKVTSELISAAKNLKAVIRAGVGLDNIDREAAKERGIKILNTPEAPTQSVAELTVGLMLNLSRNICSANASIKAGNWEKGGLSGTELSGKTLGIIGFGRVGKMVSELALAFGLNILAYDPYSSEEEMQKASVKSSELGELLSESDIISLHVPLTEETRNLIGENEFSQMKDGVLIVNAARAELLDEEAFYSAIERGKIRRAALDVYWGKKPSEKLLAFGDRVLLTPHLGSSTIEARERIGKLLVERVKDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZF6</accession>
    <name>A0A832UZF6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylneuraminate synthase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006190">
        <property type="entry name" value="AFP_Neu5c_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036732">
        <property type="entry name" value="AFP_Neu5c_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013132">
        <property type="entry name" value="Neu5Ac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03102">
        <property type="entry name" value="NeuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51269">
        <property type="entry name" value="SSF51269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50844">
        <property type="entry name" value="AFP_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFP-like" evidence="1">
        <location>
            <begin position="317"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="373" mass="41358" checksum="A1D10827D177DE16" modified="2021-09-29" version="1">MIKIRDSELGGDKPVYIIAEAGVNHNGSIELAKKLVDAASEAGADAVKFQTFRADLIVTEDSEKAEYQKKDSDETHFNMLRNLELSDEDFKELKDYCNTKRVEFLSTPHSGEWSVNLLEELGISAYKIASGDLTNIPILKYIAKLGKPVIISTGMATMDEIQEAKEAINSEGNDNLIVLHCTTMYPCPEGKVNLRAMQTILDKTENLVGYSDHTQSIEASIIATCLGASLIEKHFTLDQDMPGPDHSSSIEPDELENLIRAVRFVRKNNISNPSEAFEVLNSQGYSLDSNLIETILGSPEKLPDEKELEIAKVARKSIVAMKYINAGDELTGKNIGILRPGEGLHPRHFSEIIGKHTVRNIQKNDYVLLEDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZF7</accession>
    <name>A0A832UZF7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="124" mass="14367" checksum="F62B54AFDE29BE33" modified="2021-09-29" version="1">MGILRRRRPSEAVETVTVTFVFTPGNDIARAFFRPDHKEFLVTSGAQKQYIRLETESRKSREPQTDYPLQIPKGEECEFSEPGSDPKLVVILNGKRLKRKGRSIHANLGKIKKDTRFEFELLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZJ4</accession>
    <name>A0A832UZJ4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="281" mass="31604" checksum="E68B08C0EE1D6DCC" modified="2021-09-29" version="1">MSNKKDFGFYYSVALLSLLAIIVFMQPQAGEKIPDFDEVTTINGVNIEEDLVIPEERLEEIIKFEGTLQETECNVDPDWPEHCPIKKGSREFRTCWIESTSGSSDLFATIGCGAMTIHAEFKQMASMATSREARIVLLPIPNVTARYLLALDMRINGLPRTENQEQGLVINIEEVQNHRKVVISVSDGKICVRESAEECIETPEVAEATQPGRMKWDIVGENDELRIYVDDSMIAEFTDLSLLSYQQTGNLVSLYARLNPDDVSGSVLDVEIRKAEFYNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZM5</accession>
    <name>A0A832UZM5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000005">
        <property type="protein sequence ID" value="HIJ99350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="100" mass="10680" checksum="BB3161ED1AF8F614" modified="2021-09-29" version="1">MTSPGAVVVGVFVLLAAMHIRTRLAFAFLSLCDVLAGLLLMSVPRYANVSLFSLGIESQLMFYVGVALVVKGVYSIVAGMRQPMWITVGTLITVMLAMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZT9</accession>
    <name>A0A832UZT9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L39e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl39e</name>
        <name evidence="5" type="ORF">H1011_02720</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00629">
        <property type="entry name" value="Ribosomal_L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_L39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_L39e_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="SSF48662"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="51" mass="6162" checksum="0D7E6442E49BD370" modified="2021-09-29" version="1">MGSRKHTNYKQRLGKIARHAKRVPLWVIVKTHRRVNSHPKRRHWRVGKTKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V002</accession>
    <name>A0A832V002_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="105" mass="12601" checksum="76E9A00D8EE6B0C9" modified="2021-09-29" version="1">MARKFEEWNHAYLWLQEFFDYHQRNLDLVNKYPGESTEDAIAYSLRDLLDLVEECSKVLFPGGSQVDTGRVLQKFKGVQNNFKGLRRKHHMPADERRQLEQFRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V014</accession>
    <name>A0A832V014_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="128" mass="14586" checksum="2642B2CFAA466DB2" modified="2021-09-29" version="1">MNKIPNKVRLVLKDLNQDDSELAELCISRVTELLQSSGCSDARSWATNILPMVLGEMAEVEEAGDLDEWLLDLDGAEYEVVFGVQQVFSEIQDKLAKRSSEDIRDTLIYSIEKTLSEIDRVRYQRLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V034</accession>
    <name>A0A832V034_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_03385</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006639">
        <property type="entry name" value="Preselin/SPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010545">
        <property type="entry name" value="SPP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06550">
        <property type="entry name" value="SPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00730">
        <property type="entry name" value="PSN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="268" mass="28705" checksum="08CC5B0F1CF13E8B" modified="2021-09-29" version="1">MSLFLAVQIIGIYVAIQISAFEVIPVAETVPAVKGFLLMFAAATALFLVLIKFFKRRLGFMKVLMAFIIFVGSETVFSVIFSELTALLLALSLVVIRFTYPTILVQNVSLILALAGVGATIGLLFNVSTIFIILAILSVYDIIAVYKTKHMLTLFKGTLDSGVPLALIASEKLSDMGSELKKATLKTPTTKREYTFLGTGDVAFPLILAVSALRTGFSVSAFVIVGGLVGILIIHSLLIYGKGKPIPALPPLAACTMGAYLLASYFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V081</accession>
    <name>A0A832V081_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_02630</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_S4e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013845">
        <property type="entry name" value="Ribosomal_S4e_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038237">
        <property type="entry name" value="Ribosomal_S4e_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013843">
        <property type="entry name" value="Ribosomal_S4e_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018199">
        <property type="entry name" value="Ribosomal_S4e_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="PTHR11581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00900">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08071">
        <property type="entry name" value="RS4NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00528">
        <property type="entry name" value="RIBOSOMAL_S4E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="7">
        <location>
            <begin position="165"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="217" mass="24150" checksum="7542444ED65D84C4" modified="2021-09-29" version="1">MAHLKRLNAPRSWPVKRKAHSWVTSPVPGAHSAKEGIPLRSLIRDVLGHARTAKEVTHILKTRKILVNGRVITDSRFSVGAMDVLDLGEEGRSIVMFTNKGKLYLEPYSKDYRLCRVEGKTLLKGGKIQLNLWGGSNLLVQKDEYSTGDSLKLELKDGKLSGKIELKPGGMVYVLSGNSVGRTGKIKNIDEKTKEVVLEDGKDEFKTQVSRLYPVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0N3</accession>
    <name>A0A832V0N3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="232" mass="25810" checksum="A5CA936EEE69FC09" modified="2021-09-29" version="1">MIPKKYLASLKSVGELSDDVSYFTFNLDSPMLFEPGQFVMISMDIDGETVKRAYSIASSPESTEVLAFCVKLLKDGKLSSALDKLETGDTVEIQGPYGNFLLSEPELDQLFIAAGTGVAPLIPMLKSYLENNNCEATLLFGFRHEKDFLFKKDLEKLTSSYANFKLVPITSRPHEGWTGLSGHVTAYLEDHINDIARTISYVCGHNDMVVDVRKILIESGLSPERIKIDNWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0R9</accession>
    <name>A0A832V0R9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="65"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="207" mass="23244" checksum="46CF1CF4348B1161" modified="2021-09-29" version="1">MSKNTKINMNNIIMLAVVFGALSGALTTYYITSVQTPSQEDLIKSHYDTETAVLVSPHGLRKRLGDGTTVLVDVRSQEEYEEEHITGALNVPAYRDRDHSDYGAVERIATSFAEIKADNPNKDIIIYCYSMPCMTGRKVGKMLADRGIFVKELGIGWNEWRYFWTLWNHAHEWNITKPEDFITSGPEPGEMLIETGSGCPIEGDFGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0S4</accession>
    <name>A0A832V0S4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cupredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028096">
        <property type="entry name" value="EfeO_Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13473">
        <property type="entry name" value="Cupredoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="COX2_CUA" evidence="2">
        <location>
            <begin position="48"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="149" mass="15741" checksum="CA18A830B668EF32" modified="2021-09-29" version="1">MVNKILMGILLSIVLIVSGCTGSAPESQSTQDIQEEGASVSDSPSEESDSQSADSTGEVKEFSLTVKKFSFTPGEITVKKGDTVRLTITSEDTSHGFSLPDFDVNEQIPSGESVSIEFIADKSGEFTFRCSVFCGSGHGSMSGTLIVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0S9</accession>
    <name>A0A832V0S9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_03060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="371" mass="42820" checksum="DB93F04D10F20221" modified="2021-09-29" version="1">MAKEYTVTPWEVHGDVDYNEIVKEFGTKEIDDSLLKKIEKYGKLHHFLRRKHFFAHRDLDIILKDYDKGKKFYLYTGRSPSGPIHLGHMIPWMFTKWLQDTFDAPLLFQIPDEEKFLFKNNLTMEESEKWATDNILDIIALGFDHKKTSIFKNTEYAKTMYPVAVEISKRITLSKAKAVFGYTNETNIGSIFYTAMQSVPAFLPSIREGEPTNCLIPYAIDQDPHFRITRDVAPKLGYPKPASINCKFLPSLKGDSKMSSSINETCIYAGDSPEEVSSKIRKYAFSGGRDTLKEHRKKGGNPNIDVAYQWLTYFEEDDKKLEQVYHAYKSGELLSGELKEICIETINKFLSTHQKARAKAESKVEKFMLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0W1</accession>
    <name>A0A832V0W1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phorbol-ester/DAG-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_03410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002219">
        <property type="entry name" value="PE/DAG-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="SSF57903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50081">
        <property type="entry name" value="ZF_DAG_PE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Phorbol-ester/DAG-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="54" mass="6188" checksum="60EF56033B30E003" modified="2021-09-29" version="1">MDCVKCKQKTEDGIQCESCDSSLHRKCGRKYADQFLCKKCLKNARFETTMSSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1G6</accession>
    <name>A0A832V1G6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nop domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D RNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="PTHR10894"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="SSF89124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nop" evidence="2">
        <location>
            <begin position="207"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="321" mass="35757" checksum="DC1A031664684ECD" modified="2021-09-29" version="1">MSKQIVVTPFGIYSSEGGKLSLESEFSASPAEAAKKLRDYEKTETLPELDSLLEAGAEFSADSEASIDARLRLDELAKERGIEARKYIYSLNQELTKLRMHEELASPDRRIIQAVNSLEEMDPLVNVLSERLREWSSLYSPELSRSVQKHDDFLIKLSQQKEISSELGAVFERADTEVPKDIAHSLSDMYETRTKLREYLEKMMKDHYPNLEAVAGSHIGAQLMALVGGAKRLATKPSSTVQVLGAEKALFRHVTTGAKPPKYGVLLHHPVIQDLPKHLRGKGARILAGKISLAIRADVYGSGFSADKLNESLDKRIKNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1R6</accession>
    <name>A0A832V1R6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HPP family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007065">
        <property type="entry name" value="HPP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04982">
        <property type="entry name" value="HPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="170" mass="18240" checksum="980850ED31E425E2" modified="2021-09-29" version="1">MRESVFVALERTLLTLVTISLFVFLYGQILASPILLAAFASSVFIVFGHPESKMASIRSVVGGQMVGAITGYGVSLVIPGFTPLSAGIAVAAATLFMILLGVQHPPAAGTSMSFVYNAGGLSSGSNFWMAIVVILSLSFLKIIFKTGDWLLHRTGKEWSNLHKWFKEKAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1V8</accession>
    <name>A0A832V1V8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA topoisomerase 1</fullName>
            <ecNumber evidence="10">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">topA</name>
        <name evidence="12" type="ORF">H1011_01595</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="10"/>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03362">
        <property type="entry name" value="TOPRIM_TopoIA_TopoIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005739">
        <property type="entry name" value="TopoI_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034144">
        <property type="entry name" value="TOPRIM_TopoIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PTHR11390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01057">
        <property type="entry name" value="topA_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="5"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="10">
        <location>
            <begin position="200"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="693" mass="78463" checksum="18014F23A16C70E3" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1Y8</accession>
    <name>A0A832V1Y8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF47 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0111 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000011">
        <property type="protein sequence ID" value="HIJ99546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002727">
        <property type="entry name" value="DUF47"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018445">
        <property type="entry name" value="Put_Phosphate_transp_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36536">
        <property type="entry name" value="PTHR36536"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01865">
        <property type="entry name" value="PhoU_div"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="220" mass="25350" checksum="64D1B322AB7844EF" modified="2021-09-29" version="1">MVEFFSILKPDKTDEFFSSLEIFIGHIHDSVVSMQKTLEHYCNDDIDAVKELSEKVLRSEKKADVIRRHMEQMLYKGVLVPFGREDKYNLLEALDDVADRAEIVVRIARIERPKVPDTIKDGLKDMASLVVKTSKNLRKSVLSLDKDLDKAIQEATSVELDRERVRNEEFKLLEILFSDKKNTKLQLMLIKELISLLGRVADRAEEAADRVTTIAVKYQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V208</accession>
    <name>A0A832V208_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="102" mass="12215" checksum="F26A578D3D6D2B8C" modified="2021-09-29" version="1">MSKEEVKLRERIKELRKKSKVGKRSTIQEYIEALTELIPILEKLREIPQRDLEFAEKKLDDLQKRIKTIDDEITLARGEQTKYYTLKLERGEKTRLGEIEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V227</accession>
    <name>A0A832V227_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">50S ribosomal protein L21e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpl21e</name>
        <name evidence="4" type="ORF">H1011_02165</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00369">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_L21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_L21e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022856">
        <property type="entry name" value="Ribosomal_L21e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="96" mass="10817" checksum="6E625BB7750D2570" modified="2021-09-29" version="1">MKHSKGFRSRSRHKLRGGRFSIAEALKKLSDGARVVVRLNPSVHSGMPHPKYHGQQGIVEGRRGRAYLVSINDGNKNKTLLARPEHLVKVKEQVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V238</accession>
    <name>A0A832V238_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_02240</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003568">
        <property type="entry name" value="Cyt_c_biogenesis_CcmF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01411">
        <property type="entry name" value="CCMFBIOGNSIS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="396"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="420" mass="46049" checksum="EB4DCBEA82D7D281" modified="2021-09-29" version="1">MAKKKLDFVDLVFFGIGAIVGTGIFVIPSLAASLADAASFWVWLELGMLTIFMALCFAEFSSVYPNAGGLHQFVKETFGSFIGFMSGWIAWLISWFTIASLAVAFSYYISYFIPLGAVAIPLVAIGILVLTTVINLRGMHWGLTTQYILTSVSILVLWFFVTWGVYWIDVSNYVPTTQITMTSMFAAAVFVIEPFIGWETITFFASDAKNPTRDIPRAIIYSSVFVTILYSAVIFVTLGLLSSGQLSASLSPLADAANVFFNPWGGWIVGIGAIAILLGCINSWIVSTGRLPASLAHEGYFPKFLGKIDEKTGVPTRGLLSQLLFASIAVYFAGFEALIYVLVSLAMILYIILFTAIPFHRRLGKDIPFKLPLNPLVPAISIIVSVFVLLNVERIYLMIAIGLILSGTFVYFASLKLIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2A7</accession>
    <name>A0A832V2A7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="141" mass="16694" checksum="3063A84BAE709243" modified="2021-09-29" version="1">MFKRTKKFGDRPETEIAIEVGLMFIALFITKIVMAELLILLTIVVLLLANFAVRYERNEWKVFVLGTIVGFTMEWAGDALYHQFTWKQTFVDQTLFGMPLWLPALWGYGFVMMRRIGNVLVHEKRYKRDKPKAYHKLFNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2C5</accession>
    <name>A0A832V2C5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="384" mass="43333" checksum="3161421926B83373" modified="2021-09-29" version="1">MADSIIPRVLERASDRRFSNPIEFNKKVQKVKRILRHEDWEEFKRDRFDNKSNLFSDLRLFEDRALPLRGVYISALLEIEAEFLLSQGSSGPVEILNVSDWSTRQRKTFKDLIENCEILKGSQAIAESHIAGSYTISGVSCKSIGNGSYLRKIVLKNIECEAVFSATSSNAAISQIKDAIIEKSSISVVFERAHVSGRVEITELSGYKHRLPSLFKRAVLGIQDRGEDLEVSVIIKDSKISEAFTSALLSGKIYIDGITSISLFSDSALLTNDLVVNNCTVRSILTGAGSRQSPSYGIPVDVQKLVLFNVKGLEDERDVLEDAVFRTSTRKKFHIYYDEGSFLAENFQQIRARFRGRELRGAVISENDLERIVREMFSKQRTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3H0</accession>
    <name>A0A832V3H0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11378">
        <property type="entry name" value="DUF296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025707">
        <property type="entry name" value="DNA_bp_PD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005175">
        <property type="entry name" value="PPC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03479">
        <property type="entry name" value="PCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016702">
        <property type="entry name" value="DNA_bp_PD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51742">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="138" mass="15724" checksum="D8B715194C4590A3" modified="2021-09-29" version="1">MKIYKQMDNEWFGRFSEGADLKESILQLAKENKIESGYFNIIGAVKDSRFSYYDQTQKKYLEMHLDENAEILNCTGNITLLDREPFVHAHITLADNEGRAYGGHLMAATIFSAEIYLKKFPNPVERGPDGSTGLKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3I1</accession>
    <name>A0A832V3I1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="154" mass="16882" checksum="33C4C6BE52205F2F" modified="2021-09-29" version="1">MGDEFGLLMVPKESGSVSTFMKEISSSNFESQVSKTLEKMRISPTKISLSEYDKGLGKKGTSLEGFKFIKYSVKLRGKKKSFLRTVPWKSDSELTILVGTGDNKRDGVMLSSTRGSVSDMRLIFGSLVERVAELMGGEGVLHWSQSTKTGSLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3I8</accession>
    <name>A0A832V3I8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TCP-1/cpn60 chaperonin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_00285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03343">
        <property type="entry name" value="cpn60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012714">
        <property type="entry name" value="Thermosome_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="PTHR11353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02339">
        <property type="entry name" value="thermosome_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00995">
        <property type="entry name" value="TCP1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="547" mass="58478" checksum="138E54E965C69F32" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3R1</accession>
    <name>A0A832V3R1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="170" mass="19870" checksum="5AAC3D88D9C8A287" modified="2021-09-29" version="1">MAEKHHSGMQPASRGIPSKEALWLSDIRKLRDQWKYGKNVRLEMEQILQIVFPDQYQAKYYEVSNAFMALLLEKLELEGDDVGAFLRDNNFSKATFYNVILPRLRRVGMVKTERRRFHHSKSTQKHYQNIIRPSTQFSKFFGHLAKEYESIVETAKARASDASEEERGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3W9</accession>
    <name>A0A832V3W9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Replication factor C large subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000010">
        <property type="protein sequence ID" value="HIJ99534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="37"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="384" mass="42435" checksum="E17A644FA6C2BEBF" modified="2021-09-29" version="1">MGNELWVEKYSPTKIEELVGQEKAAKTLRTFVNNYKPGSGILLIGPSGCGKNVLVSALAKETGNELLETNASDVRKKADIEEIIGGASRQMSLTGDGKIILVDEADGIHGNSDRGGVPAILKIVQNSAFPIVLTANNPDVRAVKELKKKCKVVKMAKLSEADVAKRLKDILSSEGIEAADSVIMQIAWRSEGDMRIAINELQAVSTGRQKITKENLEHLGEHGKRIAISDALKAIFKTKDADFIRKSMFACDVAPEEIMLWIEENIAREYGDASEIAEAYDKVSRADIFLRRIRRGQQWALLSYASELMSIGTARAKKEKNGKSIDYVFPQIIAIMGRTKFQRAKRDSEAAELGEALHCSKKRVLEQMPYFDIIFQHQGQGSNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V808</accession>
    <name>A0A832V808_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="352" mass="40053" checksum="BF5E9B01355B95D0" modified="2021-09-29" version="1">MPKLDEQILGIIRNAGPSTPMEIASRINGTDSLIVGAVLADAESQKKIKKSKRRIGGGLRYYYFPDQLGILQKKISNTLTTHEKEVLQILMKENLLGEFEISEQIKIILPNLEDLIRSFNIEHDGNTYRCWSSPTMNEKLAFDTAMEKITGRLGTGEAEEVRKETAEEKIQKELKTENPRATTEEIKPEVKVQEKVKAAPKIEKKTTTSDSRQEKLSKEEKVQKETEEEMRDRIRKEILREIEGDFGDIVLRWLETKDIDVRSETSVPDENTYELEVKVPTPLGRQTYMVKILDFPKKPASQNDVAAIGTEAVTRRVPAMVISSTGFAKTAIKYVDKELKDLVFLIDKNDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V871</accession>
    <name>A0A832V871_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="2">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="2">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">thpR</name>
        <name evidence="4" type="ORF">H1011_01230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014051">
        <property type="entry name" value="Phosphoesterase_HXTX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02834">
        <property type="entry name" value="LigT_PEase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02258">
        <property type="entry name" value="2_5_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="17"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="101"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 1" evidence="2">
        <location>
            <begin position="48"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 2" evidence="2">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="186" mass="20891" checksum="9CAFBC66C1B194DD" modified="2021-09-29" version="1">MSELKKKPILDRCFVAVDIDEEVRNRLSEVQNNFSDLGLKMIKPENMHITLRFLGDVDSEIAKEDMRFFDGFPEFEISVVGLGSFPRILWAGVKEGASELEELSQIAKKISVGNVYKESRNFSAHITIARDIDGAIKTAAEDIEGMKNMDFGRFSVKEIKLKKSSLSAEGPLYSDIYSVRTMSAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8I5</accession>
    <name>A0A832V8I5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="10">5.4.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">glmM</name>
        <name evidence="10" type="ORF">H1011_02035</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="10"/>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03087">
        <property type="entry name" value="PGM_like1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024086">
        <property type="entry name" value="GlmM_arc-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03990">
        <property type="entry name" value="Arch_GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="7">
        <location>
            <begin position="2"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="8">
        <location>
            <begin position="149"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="9">
        <location>
            <begin position="250"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="6">
        <location>
            <begin position="369"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="428" mass="45919" checksum="EB009B3D0FC20811" modified="2021-09-29" version="1">MELFGTSGIRGIYPDFVSEELFTKIGLSLGTQAEGTVCVGRDFRTSSKQLQSALVSGILSTGAEVLDAGTCPTPVVAYATKKFKASAGAIITASHNPPEFNGVKLWQPDGSAYSPKMEKEIEALIKSGKADRAEWSEVKNLSSVEAVERYMEDITASFSLEGGLKTVADCGNGASVLTAPEVLSRVSENISLFAEPDGMFPNRMSEPSEKNLSELKKKVLSSKADLGFAFDGDGDRVAVIDNQGDFVKQDTLLAILAKSELGKNSTIAVPVDTSMAIDEIGAKVIRTKVGDVYVSEALKRENGVFGGEASGCYIFPEVHLCPDGLLAALKILETMELSGKSMSELVAEIPSYPILRGVVEGDREKSFKKLSEKAKKLGGELSETDGIRIQLEEAWILVRKSGTEEKVRITVEAHSEAMARQLMGSIMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V935</accession>
    <name>A0A832V935_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription initiation factor IIB</fullName>
            <shortName evidence="5">TFIIB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tfb</name>
        <name evidence="8" type="ORF">H1011_03565</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00383">
        <property type="entry name" value="TF2B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023484">
        <property type="entry name" value="TFIIB_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="PTHR11618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="TF_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="repeat" description="1" evidence="5">
        <location>
            <begin position="115"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="repeat" description="2" evidence="5">
        <location>
            <begin position="209"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="5"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="306" mass="34638" checksum="E4C56A89163B2720" modified="2021-09-29" version="1">MAEKCPECNSESVSFDSKRAETVCNKCGIVIDERQIDTTQEWRAFDYEQRKKRDRTGSFLTYTRHDKGLSTSIGDQGYSDLYKLSPSKRASFYRLKRWHKQVSTATERNLRFALSELDRISSTLSLPKNIRETTALIYRKAVTKGLVRGRSMESVVAAALYAACRKHNVPRTLDEIAEASNVKKREIGRTYRFITRELKIRLLPTSPIDYISRFSSSLKLSPLVQEEAIKILKQAQEHDLVSGRGPTGVAAAAIYVSSTLSNEKRTQREVAEVAGVTEVTIRNRYKELIEELGIADKMSEASAKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V948</accession>
    <name>A0A832V948_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000017">
        <property type="protein sequence ID" value="HIJ99880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="174" mass="18536" checksum="B03F259FADAE6E9A" modified="2021-09-29" version="1">GAGGSGGAGGSGGGGGMIILLVAAVAIILFMFMKNRGGGRRGRPARSEPPEDAIPAVPLDPVQDELEIETSNINIVGSRTGPLDMFFTVSLKNHGENPRACGQLHISGVTLKKDVLIDVFDRRAKDPVIIPPGEKVTLYNDGGEYELIVELNPGYYSIPPNDRQFQVEVVRLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X4V0</accession>
    <name>A0A832X4V0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="153" mass="17715" checksum="FFE161A6FE4F27EB" modified="2021-09-29" version="1">MTRNEKSEEVEKANGDLMELEGIHFDNVLRSIDSHIGDVFNTDSLQTQFLNTVETLKEKEIKMREILLLMNGARKTLNEELSHRVKTENNLSENLAVLKQEKERIGELLLLHEQDIYTTQEEQKKLERLTENLSLALVDMQNKLAENGQAPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X4W9</accession>
    <name>A0A832X4W9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Preprotein translocase subunit Sec61beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_00405</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="56" mass="6037" checksum="7BC09CCCBDF38863" modified="2021-09-29" version="1">MAKKTKINMPGSGGGIFRVSDEEGTGLKFKPEHVIMASGLIVVIELILHLYGRALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X540</accession>
    <name>A0A832X540_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021655">
        <property type="entry name" value="Put_metal-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11617">
        <property type="entry name" value="Cu-binding_MopE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="10"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="472" mass="50733" checksum="7B74CF436F4B46F2" modified="2021-09-29" version="1">MSDKAETNKLVIIGVAVLLLAVGSYFFFTGPETGGKFIQIQQFSVKECRQACNIYYGTGVVEDVGPVSIGDTSPPGSGGPPTGGPQAFEYAEACQQLCIMASDGDRDGYAGLPEGSITRMAKDFGLDPAQLEFPDLDCDDAQALMNPGQQEVQCNTLDDDCDGDIDENNPPYGCNAIDGKICTDSDGGSDPYTNGSIVYEKYDVNTGSLLATSYPSDMCLSYYNSAGQEVDGLREYYCDSVNDVQYEYYECSCSNGVCIDGDSDGYNSLVDCDDNDANVNPGSTQREYLRSPDYNCDGKLTSPVGTIFVHGTASTGNLGGLSGANTKCTAEAAAGGLTTSGVTWIALLSDSNNAIKDRLPDVHYRDIWGNSLATNKSDLLDGSLSIGIDRKTDGSRIVSSGNALVWTGSNQEGGNTWWRTQSYAVATCADWTSNRWQGIGGRTSDRSKNWIDTNVQWHCDWDNIYLYCVRTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5A9</accession>
    <name>A0A832X5A9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">2,3-bisphosphoglycerate-dependent phosphoglycerate mutase</fullName>
            <shortName evidence="4">BPG-dependent PGAM</shortName>
            <shortName evidence="4">PGAM</shortName>
            <shortName evidence="4">Phosphoglyceromutase</shortName>
            <shortName evidence="4">dPGM</shortName>
            <ecNumber evidence="4 5">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">gpmA</name>
        <name evidence="6" type="ORF">H1011_02520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="4 5"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046538">
        <property type="term" value="F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01039">
        <property type="entry name" value="PGAM_GpmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005952">
        <property type="entry name" value="Phosphogly_mut1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11931">
        <property type="entry name" value="PTHR11931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01258">
        <property type="entry name" value="pgm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="21"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="183"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="4">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="4">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="247" mass="28656" checksum="BDDF7FFCAE8E6E44" modified="2021-09-29" version="1">MIKLVLLRHGESVWNLENKFTGWTDVGLTEKGEEEARDSAKLLSEGNYVFDEAYTSVLKRSRETLKIVLKEMKLSEIPVHRSWRLNERHYGALQGLNKTETARTEGEEKVFLWRRSYDIRPPALSEDDDRHPKNDELYADLKETELPSTENLEDVVERVLPYWNTQIAPALKGGRKLIICAHGNSLRALIKYLDHISDEKITKLNIPTGIPLVYELDKDLKPIKHYYLGDVEKVRIESEKIAKQLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5C4</accession>
    <name>A0A832X5C4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">30S ribosomal protein S19P</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rps19p</name>
        <name evidence="7" type="ORF">H1011_02675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005713">
        <property type="entry name" value="Ribosomal_S19A/S15e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01025">
        <property type="entry name" value="uS19_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="128" mass="14731" checksum="11569EC82F25B660" modified="2021-09-29" version="1">MARKEFKYRGLTLEALQKISVEEFILLAGSRARRSLTRGMKDRRAIFLKRSRKDSKTVLRTHCRDMIVLPEFIGRTFAIYNGKEFVSVKMLPDMVGMYFGELSPTRKRVMHTAPGKGATRASKFISLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5H4</accession>
    <name>A0A832X5H4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041120">
        <property type="entry name" value="PIN_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18477">
        <property type="entry name" value="PIN_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="135" mass="15035" checksum="40E5DA1FE9816FA1" modified="2021-09-29" version="1">MKVNKVILDTNALLIPGKKGGRDIFSDLEHFLGSYDAIIPSFVADEVRKLSETGRGQTKAAAKLALNHIIPKARLVEVDKGQRTVDSAILAFAQESGAYVYTNDRGLRDRAKKRNILTIYISQKKYPKKSRHPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5I7</accession>
    <name>A0A832X5I7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mrr_cat" evidence="1">
        <location>
            <begin position="23"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="155" mass="18066" checksum="851C33902353387E" modified="2021-09-29" version="1">MKKDLEKIEEELKEGADLEAILEKYDWRDFESLVASIFAERNYKVKTAHRFKHDGRHQIDVVAEGFREIFCVDCKKWSDRKGKLSALKKAILDQKLRTQALKDSTDNKSEVFPLIVTLLQEDIETHGNIPVVPVWKLNSFLEDFPQNRGQLHKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5J3</accession>
    <name>A0A832X5J3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="247" mass="28561" checksum="B9670AFF6AD63399" modified="2021-09-29" version="1">MSHPKFQTLVIPDRSVVRQYPGSPEQMVTIFYDALEQFIEPTRSYTKRKIIIKLAKYVSELLTLPYTETKANKMVADWEQYVSKGIPVPLSYCIKEDLITCFHRSVFLQILFQEHEIESCIQTGFTSDIVDSEKSPVPIEDYMKYSIGVPSWELHVWNIAYDGRVPLYVDSSLLLDKKPSISSLENFEYKSARTYFRANLGDGYYIHNLGDFPDFESRNTRGINVEALTEKSSRSLRTVLKKEALLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFK4</accession>
    <name>A0A832XFK4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl1</name>
        <name evidence="6" type="ORF">H1011_00255</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds directly to 23S rRNA. Probably involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_A">
        <property type="entry name" value="Ribosomal_L1_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023669">
        <property type="entry name" value="Ribosomal_L1_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="226" mass="24680" checksum="24660312A008CFBC" modified="2021-09-29" version="1">MEQKHVQEAIKQARENSKKRNFSQTFDLVVSLKDFDLSKPENKVKEEVVLPAGRGKPVRIGAIAEGELAENAKKSGIEIIVSKADLQKLQDDKKSAKKLVNQVDVFIASPDLMADIGKTLGPLLGPRDKMPKPLPPTAPLEAFIQRTHKVVNVRTRDQPIIQCLVGTEAMKDEEICQNLMAVLTVLENKLPKGLGNIKAAYVKLTMGKPALIGGSKIKADSKGGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFK7</accession>
    <name>A0A832XFK7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="70" mass="7682" checksum="65F3DFCC5C609516" modified="2021-09-29" version="1" fragment="single">MVISATMSILDMAPSVKEASDRFVLQSRTLDISNLLLNDPGLPADWNSGNLPDRIGLAEYNNFSNSTLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFL4</accession>
    <name>A0A832XFL4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="159" mass="17776" checksum="DFDFBC36C383D783" modified="2021-09-29" version="1">MTNRKAYDELSQDNKEKLVCALFATKYPGLSSDCGVDVDVAAYSLRAACVLIAEEEDELVKKIIVLLEEHNDFIESLSSEILTQYVSDLNKSDEFEKGRDELVLITGRKWESSSFSDGGKKVLTVLDMDSLLAGIEKHSSKDTKQAKHLRNLAKTFNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFR9</accession>
    <name>A0A832XFR9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="116" mass="12532" checksum="AB26D2C18AAE5D38" modified="2021-09-29" version="1">MLKNSKGHLRLGNIILSIVVLIFGGILFSLAGKIRVLSPNILTAFILVVVVAQIMNVLINGFMIHDLISIVPVTLISLFILKAVFFGGDAFGSFLIGNVQIVIILLIGLDLYKTIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFV8</accession>
    <name>A0A832XFV8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000011">
        <property type="protein sequence ID" value="HIJ99543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="213" mass="22837" checksum="280242113D48DDAC" modified="2021-09-29" version="1">MTEKEIINYVKEQLAAGHSPDEVRKALDETGWKSIEVEAAISKALPKKVRPQTAETNEDVKKAKTNRIVFISGIVLGVILLIVLVTLVAKSGVWKGVELQECGSDEACLKSALMSCSPATGLTSKGAGDSMAVSYTEVKGMKGDKCKVFVRIEDAGSVLGITVKGRSMDCEIPTSLLKETGTISVSNVDKIKDYCEGTLVEFAEQVVNTVQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFY6</accession>
    <name>A0A832XFY6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_02310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="138" mass="15247" checksum="776F05348B571A04" modified="2021-09-29" version="1">MAKNADTGIISTGKKKTATARASFKEGKGNIRINSQPLEQWGSDYERGLIIEPLQIAQSYISNCDISINVAGGGRVGQAVATRTAIARGIYKWSKNNEKLRQAFLEYDNKLLAGDSRLKEACKPGRSKARARRQKSYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG19</accession>
    <name>A0A832XG19_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpl3</name>
        <name evidence="7" type="ORF">H1011_02695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_A">
        <property type="entry name" value="Ribosomal_L3_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019928">
        <property type="entry name" value="Ribosomal_L3_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044892">
        <property type="entry name" value="Ribosomal_L3_dom_3_arc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="PTHR11363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03626">
        <property type="entry name" value="L3_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="325" mass="35909" checksum="21430B431F557192" modified="2021-09-29" version="1">MPRIHSPRRGSMAYSPRKRAARIYPRVRTWPISDDPKLLGFAGYKAGMTHMFVRDPRKDSPTSGKDVFTPVTILECPDIVPFAIRFYKRSAYGFTPSGELWAENLNSISPHIAKKINIPKKTPSSPPSDADRVTLLVSTLPSEASVPKKKPEIFEIAVGGTEFEDQLKFAKSLLGKRQKPNNVFKAGEYIDVVAVTKGKGMQGPVKRFGVKVDYRKGHSKARHVGSLGNRASPTRWTVPMAGQMGYGSRTEFNKMIVQIGEKGDAINPKGGFVNYGVIEGSYIAIKGSVPGPAKRLVRLRAPIRSKQARVEPEITYISLESKQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG50</accession>
    <name>A0A832XG50_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DASS family sodium-coupled anion symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_03170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="368"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="569" mass="62585" checksum="CD0F9887A0401704" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG82</accession>
    <name>A0A832XG82_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="245" mass="26100" checksum="56304E4429ECDB9D" modified="2021-09-29" version="1" fragment="single">MAANAFGGKNLAVLGSLVLILVLVGYTFFTGGAETSGKFVSVAESDLVAHYTFEGGSPMDNVAPGSLGSHDGTNKEVTFSDGVLVSDGKGYMELQNHADINPVEGFTIASWVNLDESCWADSSSSTGFSGSSPDCTYGKSYGTIINNRDGDINTGLYWLNFHHGNIYGYIVGGTYRPSSSSQAAPPTRNTYTEDWQNAKNCKIPSPTKLSADTWYHIAYTFKPLGTGQAELTCYYNGVAGTVRTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHA8</accession>
    <name>A0A832XHA8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="140" mass="15855" checksum="0B190277C18962A7" modified="2021-09-29" version="1">MIKTKLFEFMYGMDLWSIPIVLALLATAFSLPLRMWIFNGRNYYSTFKGKFRGFVFYSTIMEELALRLIMLPILVGMFGLLGGISALTISYMAYYAIVYGPVFAADALVIGVLFSYAYIDFGLPVVIAAHLFYKMLNATF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHF7</accession>
    <name>A0A832XHF7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">D-tyrosyl-tRNA(Tyr) deacylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_01025</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018033">
        <property type="entry name" value="Deacylase_DtdA_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007508">
        <property type="entry name" value="DtdA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34667">
        <property type="entry name" value="PTHR34667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04414">
        <property type="entry name" value="tRNA_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016210">
        <property type="entry name" value="UCP016210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="235" mass="25923" checksum="C012FF30FF7FC4C5" modified="2021-09-29" version="1">MNIFEHCSELGLDDICIKLEKEAMFLDEPDSKADVFIAASSHYSSTGKPALVTHPTGNWGKAELGGEERTLSMSYPAGQKKGLQFFAQNPVEIFEVTMEVSHHGPTNWEKPLFFIEIGSSEREWKIKEAGELVASAISEIIDDSDEYDSAVAFGGTHYCPSFNRIQIENPNIAIGHIAPRYASEFLDEKIVLEAVKKSSAELAIIDWKGLKSEARGKVISALAEAGIEWKKSSEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHH3</accession>
    <name>A0A832XHH3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF192 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="107" mass="12298" checksum="35EDEDAC30BA7B4D" modified="2021-09-29" version="1">MAKVNGISVEIADSLFEKVSGLMMRKKIKPLLFDFRRDSTILCSIHTFFMLKPIDIVYINSNKVVVQVIKARPWRAYYPQQKSRYVLELPAGMGKKFTTGKKITISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHK5</accession>
    <name>A0A832XHK5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ferritin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071771">
        <property type="term" value="F:aldehyde decarbonylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022612">
        <property type="entry name" value="Ald_deCOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11266">
        <property type="entry name" value="Ald_deCOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="215" mass="24480" checksum="F350499CE8C97085" modified="2021-09-29" version="1">MAETISDIINDPICSFAKGEERGVHLLKQLILFAPNNEAAFELRQQIEDEVGHAELFNTRLKDLDIDCEGLSKNLDSLYDYAQTCVDEKDWVKSVSVQAVIEELAMASFIYRYPELDEKTQTVLKKVIEDEKRHLAFCLNQLVKFADSDSRARTEEVHKNSISIMRAAAEQEGLSKDQLNDAKEIMKKAYFLHNSRLKKIGIALPKVSFSKTKPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHL0</accession>
    <name>A0A832XHL0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="158" mass="17515" checksum="67117AE715BEAE1E" modified="2021-09-29" version="1">MVIAPKVKLELKRTLHQVFEPKKGRVEVQILSDLEPITKDIINTVADVVRNADKGTDIEDMTEEVQKVAEEKVNSGSWNLYGTVVAVGDLLQNGNSLKGLEKDQQAKVRILLGDVIGATMAEIVESLDRLEGAAGIESRTIINRVKNYYSKKWVARSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHP1</accession>
    <name>A0A832XHP1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L32e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_02605</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_L32e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_L32e_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="PTHR23413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="SSF52042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="19"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="123" mass="14107" checksum="279390989F9E407D" modified="2021-09-29" version="1">MTTISERKSLIKRLRKKKPVFRRQESTRYKRVPTTWKAPKGRQSKQRLRKGGSPKCPGTGYGTPKEVRGLHPSGYEDILVKNISDLERVEPKTQAVRFSARLGKNKLKGFRETAKKLGMKVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHR9</accession>
    <name>A0A832XHR9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LamGL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_03155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="LamGL" evidence="3">
        <location>
            <begin position="986"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="1658" mass="176963" checksum="B3B66AFBD56ACDA2" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHV3</accession>
    <name>A0A832XHV3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="90" mass="10678" checksum="C089057A1EBB3001" modified="2021-09-29" version="1">MIRKTIILEDEVYEALQKFRAEMLMVGKDISFNAAVNALLFNGIIEAQDMSRERWRELRGFQSAHDEFSEEIDKHIEQMLKRMKKIIGEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XII1</accession>
    <name>A0A832XII1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L44e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpl44e</name>
        <name evidence="4" type="ORF">H1011_00570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01476">
        <property type="entry name" value="Ribosomal_L44e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_L44e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="PTHR10369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="26"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="92" mass="10967" checksum="6BB379698DF42C57" modified="2021-09-29" version="1">MNIPKTVNMYCAWCKKHNAHGIFVSKKRQKRTLSKGQRRFKRKMEGYGSFPKPMPTGKKPTQRQDLRFKCEECKKSNTRSKMPRVKKFELTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIJ8</accession>
    <name>A0A832XIJ8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000006">
        <property type="protein sequence ID" value="HIJ99361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="143" mass="15576" checksum="6A423389D816738C" modified="2021-09-29" version="1">MTLRSRKAQGGGVPLGVMLVGILVLGMGIGLGAYQIAGASSGDLIRWATIYGGVIDSMMMTDSDISVANDCIKDYVFSLSEDDPYISVKAGDGKEGARYRHLERNNIVVEDSSVDCRNYNVMIIHKEDTEGEMVLWLEGRRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIL8</accession>
    <name>A0A832XIL8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013701">
        <property type="entry name" value="DEAD/DEAH_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017170">
        <property type="entry name" value="Lhr-like_ATP-dep_RNA_helic_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045628">
        <property type="entry name" value="Lhr_WH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08494">
        <property type="entry name" value="DEAD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19306">
        <property type="entry name" value="Lhr_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037307">
        <property type="entry name" value="Lhr-like_helic_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="41"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="270"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="865" mass="98473" checksum="226B2A5635A912B3" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIM7</accession>
    <name>A0A832XIM7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6 9">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="1 6 9">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pgk</name>
        <name evidence="10" type="ORF">H1011_01420</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6 9">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 9">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="1 6 9"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6 7">
        <location>
            <begin position="22"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 7">
        <location>
            <begin position="62"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <begin position="356"/>
            <end position="359"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="406" mass="44149" checksum="3D33F4C3C2B158CE" modified="2021-09-29" version="1">MSSFNTMDDFDFSGKTVLVRLDLNSPIDPQTGDFLDIRRIEKHAITVKELSEKGAKVVVLAHQGRPGSRDFTTLEKHTVYLQKEVGLPIEYIEGGLISPGVVEKIKEMNKGEIILLENVRFLSEENISQPSDVQAKTHFVGVLAPLADIYVGDAFATAHRSQSSIVGFPELLPSCAGRVMEKEILMLSEARNSDARPSVFSAGGAKVRDSLKVIAHFLDREVVDTILTSGLVASVFLVAKGYKIGGLEYMENYNSLIRKAKILYNDYPDKIILPEDLAADKYGERIELPLSELPIPYKISDIGSKTAKNYSEILRSAKTIIANGPAGIFEDENFSKGTNEIAKAIAESGGFTVVGGGHIATAIRNLNLGDKITHISTGGGACILFLAGEKLPAIEALKKAKERESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIP0</accession>
    <name>A0A832XIP0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gfo/Idh/MocA family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="311" mass="35200" checksum="1A068F3F8C699C87" modified="2021-09-29" version="1">MKVIFFGLGSIGERHARLLMDNFEHELYAFRSGKSSGKNSLGIEEVHTLEEIEKISPDVAFITNPTNLHISTAVQCASQGISLFVEKPLSHNEEGVQKLMDAVKSNDLSLYIAYCMRFHPVIKWLKEHLKNNKAIHATVRVSSYLPNWREGVDHLTHYSAIKDSGGGVLLELSHEIDYLYYLFGIPTIIEAVSSKASRVTTDAEDFADILLSFGGNLNCNLHMNFLSRLNRREMILDFEDHTVVADLAESKVRILSDEDDKVIELPFERDDMYLEQLNYFFDNMGKPGMMNGPDEAPKVLNTLMEIKEAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL21</accession>
    <name>A0A832XL21_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">50S ribosomal protein L16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_00650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001197">
        <property type="entry name" value="Ribosomal_L10e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11726">
        <property type="entry name" value="PTHR11726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005590">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="4">
        <location>
            <begin position="19"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="182" mass="20244" checksum="18547C9B476F7722" modified="2021-09-29" version="1">MAERAGGVYARMDGRPYTRVSNKKPRKSYVKGVPHNRIHNFESGTKRNDYTVELILRAQRDVQIKHNALEAARVAVTKTLSPLGNEYFMKIRTYPHHVLRENPLATGAGADRFSTGMSKAFGKIVGRSARVTKNQAIISVNVKKDQILLAKNALRKASMKLPIPCRTEIKELAEGSKTAASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL46</accession>
    <name>A0A832XL46_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Site-2 protease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="189" mass="21280" checksum="352C2C0C5B53110C" modified="2021-09-29" version="1">MKLLESFTKKELQDLGISVIVMSVVVAVSMRMPMMFIFAILAIGPGFILHELGHKFMAQKKGYQAHYKMWKNGLIFAAFLSIFGWTFIAPGAVYFGGRVKHSDRNVGMVAVVGPMINVLLAVFFMAFMYTGNAFLITLGWIGAYVNSFLAIFNLIPIYPLDGQKVFKWDWRIWAGSISIAFWIFSGVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL55</accession>
    <name>A0A832XL55_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004376">
        <property type="entry name" value="CHP00024_Pesterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024173">
        <property type="entry name" value="Pesterase_MJ0037"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30337:SF5">
        <property type="entry name" value="PTHR30337:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000887">
        <property type="entry name" value="Pesterase_MJ0037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00024">
        <property type="entry name" value="SbcD_rel_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="20"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="234" mass="26609" checksum="E615AB440A373A81" modified="2021-09-29" version="1">MNLTNDIEIKGLALYIPKHKAAIISDLQLGYEENLISQGVLVPFTQFEDTKERLSKDLNDLELDTIIVNGDLKHEFGRISRQEWKDVLRIIDFLSSFCKNLILVKGNHDIVLSSITKKKGVGVVDSFQLGDIFITHGHEIPEIPKGVKSIIIGHDHPAVKLRDGDVSETYKCYLKGKWKRKTLIVQPSSFLLTEGTDVLHYTLKSPFLEKGIENFEIFVVADKPFYFGKLKDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL72</accession>
    <name>A0A832XL72_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acylneuraminate cytidylyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="235" mass="26338" checksum="A7B56AA244681C52" modified="2021-09-29" version="1">MILLTICARGGSKGVKNKNIREIAGKPLIAHTIKVAKDWGKADRIVCSTDSEEIAKAAREAGAEVPFMRPAELATDESSKMDVIRHAVYESEKKYGENYNTIVDLDVTSPVRTVEDLEGCLKIFQEKDLDSVFSVTNARKSPYFNVVEINDEGYAHLSKEPLSPIVRRQDAPEVYDMNASIYFYKKEFLMKPETESPISDKSAIYVMDDISSAEIDSELDLAFLEFLIEKGEVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL88</accession>
    <name>A0A832XL88_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_01985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="2"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="304" mass="32920" checksum="54F9A8171C1744A5" modified="2021-09-29" version="1">MLDVVGFGNLNLDLLYKVDSASYGREARILEQREEAGGSAANTLVGLSRLGFRTAALGVVGSDSAGKMIVEILKKESVRISGVARKKGQTSKILALVDRAGSSTFYRDPGVAQEFELDDLDIEQIKKAKYFHMSSFVDSSKMDLQNSLVKKIGNAKLSFSPGKVMSHFGYSELIPILKKTDTLFINESELKYLMDESYEGACNRLFKLGIKRVAVTRGKEGSYVSSRKESYNIPAYPVNVVDTTGSGDAYAAGFLAGILAGRTLSESGKMGSKVASLCIQHMGAREGLPTMKQLLAKSAQEVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLE8</accession>
    <name>A0A832XLE8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 13">DNA ligase</fullName>
            <ecNumber evidence="13">6.5.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Polydeoxyribonucleotide synthase [ATP]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">lig</name>
        <name evidence="16" type="ORF">H1011_03165</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="13 14">Belongs to the ATP-dependent DNA ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="13"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00407">
        <property type="entry name" value="DNA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022865">
        <property type="entry name" value="DNA_ligae_ATP-dep_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000977">
        <property type="entry name" value="DNA_ligase_ATP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="SSF117018"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00574">
        <property type="entry name" value="dnl1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00333">
        <property type="entry name" value="DNA_LIGASE_A2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12 13" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 13" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 13" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="11 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 13 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="15">
        <location>
            <begin position="328"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="13">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="422"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="HIJ99797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="556" mass="62363" checksum="8A490DD44036C27A" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULA5</accession>
    <name>A0A832ULA5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TM0106 family RecB-like putative nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019993">
        <property type="entry name" value="RecB_nuclease_TM0106_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03491">
        <property type="entry name" value="TIGR03491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_H_2" evidence="1">
        <location>
            <begin position="308"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="483" mass="54825" checksum="B82857685B4FD0F1" modified="2021-09-29" version="1">MDTEELFKKCTEGNGKFVKGGDVANYIKDPFVIYCNEFAPEGERDKPNRFQELLSEAGMKHEVDSIEAQHPGMKSLEFTSEREGFRMALDDFFAGKEAVANSPLIYLPENLIGRADLLEKRKGESIFGNYHYIVKEIKVAKNIKRDHILQAAYYNFVLGKIQGFTPEEFYLVNRNNDIIPHKFADYKSALELSIADVLKIKSGDLTPSPTYGSVKYNWTSYTNKLAKEADDVSLIPGISGAMKAKLNASKIFTVSDIQGVDISNLTDIEGIGDVKATQFKLCAESLKSGKPVVKNKDAIVLPDAKAELYFDLEGTDEITSGAAPFDYLMGILESENGSEKYISFLAETPDDEEKIFREFLKYLDSKGDYVLYHWNTYEVTALKKLFEKYQVDGIKILERMVDLYRVSHKSVVFPLYSYSLKAVAKFLKPDSWRHDDVDAMQSIVLYNEFVDTGDREKLQKVIDYNEDDCRATLLVKQYLANLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULD4</accession>
    <name>A0A832ULD4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative HTH-type transcriptional regulatory protein H1011_00530</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_00530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00584">
        <property type="entry name" value="HTH_type_cro_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020886">
        <property type="entry name" value="Arc_TR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="135"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="312" mass="34875" checksum="BE8BBEA3DA4F055C" modified="2021-09-29" version="1">MIPERSQRENLLERAAGLLEALGFSVARQLTPSCFDLLARDGDTIFLLKILSNVDSLTEEQSIDLRRVSNVIGATPMLIGESARGETMMEHTVYERYNIACVSFKTFENALSEHNFPFVYSKKGGFYSHLNTDYLRKLMQKNNISAGALAREAGISKSSLLNYERGQGASIENIERLQEALGDLVLDPIDVFRFEEESPELSSGGSRIERIVESHFGDIGFRTAAVTKASFSLIGRSKKDIIFTGLESKSLEKRAEDIRVSSKVLGQHGMFVLKKTEERQVSGVPVLGEQEFQETVTSKQLLKLLRELEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULN1</accession>
    <name>A0A832ULN1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="438" mass="47647" checksum="826F57E08CA85DB4" modified="2021-09-29" version="1">MKRIVIITLIVFLLLSSSAYAGNILTISNASMENGSIVLHIKNEVSSVMYTNSSKHSTESLSFMVDGNSVDIKSAEANDIAYGSTKKVVLDSVWPTTGAKLINVTYTDSSSTSYPSEFWVVFAQKGLVKIDYSYSPSIADTDSDLIATFTLKSSSEAAITSLDINIPNNPRYFFVDSKGFPNSMSAGDEREFKIYLKSSGSSMSDTTIYTTVYLAINVTYAYLGYNDELSLNESIIVFNPLKVLTLPHIMTKLEGPQSSEQGTTAEINAFAWNDKEGSNKGCSLSLSLSSDDSRLSIPVTTIIPGEDLVHTYAVPADSLGTFKIEIPSDMPDGEYYLTLKGSYKDCEVNAPLSVEESVFVLRVTSATKEEAPVDEPAAGEPAEEESPGLTNQTAEPEVVEKKSFKEKNPFLFLLLLGALAGLGTFAVIHYLIRRTSYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULP2</accession>
    <name>A0A832ULP2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyltransferase family 39 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_01455</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="159"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="88"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="547" mass="62856" checksum="CB42AEE79C285792" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULP6</accession>
    <name>A0A832ULP6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="11">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">alaS</name>
        <name evidence="13" type="ORF">H1011_01530</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="11"/>
    <dbReference type="EMBL" id="DVAD01000008">
        <property type="protein sequence ID" value="HIJ99488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_A">
        <property type="entry name" value="Ala_tRNA_synth_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022429">
        <property type="entry name" value="Ala-tRNA_lgiase_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03683">
        <property type="entry name" value="A-tRNA_syn_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 11" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="12">
        <location>
            <begin position="74"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="598"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="602"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="702"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="706"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="HIJ99488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="939" mass="105292" checksum="F053F6E92ECAE6B4" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULR3</accession>
    <name>A0A832ULR3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-N-acetylglucosamine 2-epimerase (Hydrolyzing)</fullName>
            <ecNumber evidence="2">3.2.1.183</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">neuC</name>
        <name evidence="2" type="ORF">H1011_01680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.183" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020004">
        <property type="entry name" value="UDP-GlcNAc_Epase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03568">
        <property type="entry name" value="NeuC_NnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="377" mass="41458" checksum="C248AC6E86559455" modified="2021-09-29" version="1">MRKILYVTGSRAEYGLMQSTLKLIDSDSGLDLHIVATGMHLMPEFGNTITEIEHDGFALHKINSVYSEDSKEAMARFAGDFLLKFADVLKDINPDLILLLGDRAEMLSAAVAGAYMSIPVAHIHGGEVSSTVDEMARHAITKLSEIHFAATESSAERILKMGEIPSNIYIVGAPGLDSILNDTLPSKEEVFKSLGLNSSEKTVLIVQHPITLEDGKSEEHMRAILEAVKEEGLQVIVVYPNADAGGREMISVIEEYEETFNIFKSMERPLFLSIMKHSDAIIGNSSSAIIEAPSFGIPAVNIGSRQKGRERADNVIDSGYKKEEVLSAIKKAFSPEFIEKAKMCKNPYGDGKAMERIVKILKEVKLGRELLDKKIAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULT2</accession>
    <name>A0A832ULT2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Diphthine synthase</fullName>
            <ecNumber evidence="6">2.1.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Diphthamide biosynthesis methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dph5</name>
        <name evidence="6" type="synonym">dphB</name>
        <name evidence="9" type="ORF">H1011_01835</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine = diphthine-[translation elongation factor 2] + 3 H(+) + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36415"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="EC" id="2.1.1.98"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the diphthine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.98" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000011">
        <property type="protein sequence ID" value="HIJ99548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004164">
        <property type="term" value="F:diphthine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01084">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="PTHR10882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036432">
        <property type="entry name" value="Diphthine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="8">
        <location>
            <begin position="2"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6 7">
        <location>
            <begin position="112"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR036432-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="247" mass="27013" checksum="E0C735C7F545B3BE" modified="2021-09-29" version="1">MIKIIGIGLWDERSMTIKAQEEAADCDIIYAEFYTSKMFGSTLKKLEKKIGKEIQELSREEVESGKEILKKAKKQKVGLLVGGDAMTATTHAQLILDAAKAGVESKIIHGVSIFSAAAGLSGLQSYKFGKTVSIPFEDLESPYNVIEENQSIGAHTLCLLDIRDGKFMTVNEAIRKLLKIEKAREENVFMKDSLAVGIARAGSPKPVVKAGTAEELLKKNFGEPLHVLIIPGKLHFAEEGALELLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832ULY9</accession>
    <name>A0A832ULY9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol monophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="258" mass="28266" checksum="CEE2DC1ABCA81C4E" modified="2021-09-29" version="1">MNWEKLLTEIGEKASGVLKSYYLTEEGKQEVMVGAGGDITMLADIEAEKAIVDSFNNAGKFSILTEEQGLLEVENPEYYAVVDPLDGSFNFKKGVGYFSVSLGILDLNFKPIAGYVHNVVSGNTYFASENGAFKNGQKIKGNSSTDLRSSLLHRAPDSSKKGRDTVSKICMSTRNYRTYGSLALEFCSVAEGSFDFLMHAGVPRLIDVSAAIYICRQAGCSVSDFENKDFDFSNFKVNTTNVLASANDKLHHLVLEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UM40</accession>
    <name>A0A832UM40_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2-oxo acid dehydrogenase subunit E2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_02800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="4">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="5">
        <location>
            <begin position="127"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="161"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="429" mass="47070" checksum="201E6A0344C62D33" modified="2021-09-29" version="1">MVKEFIFPDVGEGISEGKLVKWSVKPGDKVEEDQIIGEIETDKAIVEMPSPYEGIIKELKVPEGGTIHVGEVLVVYEGDGEVELEKPVEKKARESVGIVGDVSTKASGVLPAGLQGRTSSAPSDHIKAAPAARKLAKELKVELSTIKGSGPAGAITVKDVKAASPEEKEPEKKTAAEAPEEEKTEKKIRVVRKYDMYGYVKRVPLSMIRKTIAKTMVKSWKEIPHVTHMDEADVTELVEVRKTEKEIAAEQGIHLTYLPFIMKAMMGALKKYPDFNASYDEENEELVIKEYYNIGFAVDTEAGLMVPVLKRSEQKTLMTLAKEMQDLAEAARSRKINIMDMQGGSITITNIGSLGGLYATPIIRPPEVAILGLGKIYDKIVPGKDGKPEVRKVMPISLSFDHRVLDGANAARFVSEIIRHLADPDILLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UP50</accession>
    <name>A0A832UP50_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps15</name>
        <name evidence="7" type="ORF">H1011_00040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_S15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_S13/S15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_S15P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="PTHR11885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S13_N" evidence="6">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="148" mass="16433" checksum="3BB0D7B2AAECB8A4" modified="2021-09-29" version="1">MARMYSRKKGKSGSERPLNRESPEWVTLSSAEVEKLIKKLSSEGISPAHIGLRLRDEYGVPDVKALTGKRLSTIIDAVEGALPSDLSDLLSKATHLKGHLLTARKDLSSKRGLDFTEAKIRKLAKYYVSSGKLPKTWKYTKSMSEVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPI9</accession>
    <name>A0A832UPI9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="17"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="81"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="187" mass="20448" checksum="29AE9F5BA999E28F" modified="2021-09-29" version="1">MAPKNTRPADISVRDSMSSPVITIRPDSSLLEASKLMRDKDIGAIIVLDKNEAVGIVTEHDFVIFVSNGTDINETKVGDVMSSPLLTISPDSSIIDAAKFMGSKKIRKLPVVENNQLKGIITSEDIAKIAPAELELLMELVSIKIDDVNEYLRETQSGDCENCSNFAEEIVKVEDRFLCRSCATSSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UPR1</accession>
    <name>A0A832UPR1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="469" mass="51796" checksum="0A08E26376D81253" modified="2021-09-29" version="1">MPKLEDMLINQSTSIKEAMAAIDRAGIRMALIVDDNQKLKGIVTDGDIRRGILKGAGNDELVSTVMNDAPLVAEENLPHQDILDLLKKNKVLGIPLLSESGKVLDMLLLEGNDVLSYTKHTIEKKHLRKILVIGGAGYIGSVLVRKLLDKGYKVKVLDNFLYGNESLSSIESDELTILEGDTRHIEDVTEAVQDVDAVVHLAELVGDPASSLNPKLTQDINYLATRNVSSVCKHFHLNRFVYASSCSVYGESEEGNLLTEESPLNPVSLYAKMKIAAEKALVEMKDDSFRPTILRLGTVFGPSPRPRFDLVVNLLTAKAVRDGKITIFGGDQWRPNVHVEDVAETIISVLEAPLDKVGGEVFNVGSEENNHTINELGDIIKNQVPSAELVIEEKDLDKRDYMVDFTKLREGLGIKLQRTVNDGIAGIISFLESHKDFNYEDAKYSNVKFLEQGKLTEFLSNGEAKTETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UQ11</accession>
    <name>A0A832UQ11_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="4" type="synonym">rpl29</name>
        <name evidence="5" type="ORF">H1011_02660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="70" mass="7748" checksum="440DC305441C135C" modified="2021-09-29" version="1">MALLRKSEIMEMSEKDMLEKLLEIRKELLTEYSKLSAGGVAENSGKMGEMKKIIAKIKTIGGIKGYTING</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UT47</accession>
    <name>A0A832UT47_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uridylate kinase</fullName>
            <ecNumber evidence="4">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Uridine monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pyrH</name>
        <name evidence="10" type="ORF">H1011_00510</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009041">
        <property type="term" value="F:uridylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011818">
        <property type="entry name" value="Uridylate_kinase_arch/spir"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02076">
        <property type="entry name" value="pyrH_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="228" mass="24590" checksum="3C92DB82826CD8F2" modified="2021-09-29" version="1">MKAVLKLGGSVFSAEGVDRDFLETVSSKIGEWARVHQIAVVVGGGKISREYGELGRKFTSDEDLLDTVGIMASRVNASLLLAALGDLAATEIPKSEEEFLNISEKNPGKVIVAGGFRPGQRTDAVSAEIAEVWGAEMVIKCTDVDYIYDKDPNKFEDAKKLESVSFEELKKLAGSEEHRANVSTIMDPVAAKILSEKGIKAAVVNGKDLENIGRILDGKEFKGTRVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTE3</accession>
    <name>A0A832UTE3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_01200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033177">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, proton-transporting domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015078">
        <property type="term" value="F:proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="6">
        <location>
            <begin position="12"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="77" mass="7537" checksum="650193F9A8A7603E" modified="2021-09-29" version="1">MAVDIGTGLLAIGAGLAVGLSAIGAGIAEKSIGAAAVGAIVEDRKNFGVALLFTVIPETIVIFGLVIAIMVLQMATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTH6</accession>
    <name>A0A832UTH6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable tRNA pseudouridine synthase D</fullName>
            <ecNumber evidence="4">5.4.99.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(13) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">truD</name>
        <name evidence="6" type="ORF">H1011_01435</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>uridine(13) in tRNA = pseudouridine(13) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42540"/>
            <dbReference type="Rhea" id="RHEA-COMP:10105"/>
            <dbReference type="Rhea" id="RHEA-COMP:10106"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.27" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01082">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020119">
        <property type="entry name" value="PsdUridine_synth_TruD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="PTHR13326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00094">
        <property type="entry name" value="tRNA_TruD_broad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01268">
        <property type="entry name" value="UPF0024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="5">
        <location>
            <begin position="166"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="378" mass="42553" checksum="0CAD83538D3314D7" modified="2021-09-29" version="1">MNDIGIRAYATKSKGIGGTIKEVPEDFVVQEIQNDMSVSSLEPSKNLPPAAAESKEYTHFTLVKKDWNQEQILKRVARRIGISRKRFSVSGTKDKRAISSQKVSAWNISPQNLLNVRIKDCELGDFSYSTERIELGDHWGNHFTVKILGASGSPEQTLSELEELGGIPNFFGEQRFGLRLNNHIVGKHILEGNIESAVREFLAGTSKRESKEGRESRESLAKNWGDFGKALKDFPVYMRFERALLDHLNVHSNDYVGAFKKLSKQTYKFFTHAYQSYLFNIILSDRINKGSSLEGSASILGYKSEPDEVESALLEKEGLSLKDFKVSQFPEASVRGDRRNFLAEIKNLSFQGKNNITLSFDLTKGAYATILLREVQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTJ3</accession>
    <name>A0A832UTJ3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="5">2.7.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prs</name>
        <name evidence="5" type="ORF">H1011_01585</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="5"/>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="4">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="151"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="298" mass="33063" checksum="E8BAE0BA41EE39E2" modified="2021-09-29" version="1">MDVVLACSKAQVLGQRIAKKFSAELVEYETKKFSDGEIYSRILGNINNKEVIIVQAGYPDPNDALIELFLVVDACRSLNSRRIRVVMPYFPYARQDKRFNRGESLSLHVIADLLKSMGVSLVVTADAHFKEDYGSYDFFGIKAYNISGGTVLAEHIKEKFKLDDFVIVSPDLGSRGMIDEAAKNVGAKTMKIDKKRKSETEVEMTAKDLDVKGKDVLIIDDIISTGGTMLKAIELMKKAGANRVFAGATHGIFSKDSFKKLEKATTYLVTTDSIQTGVMEVTLAGEIMKVIEDSRVYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UU46</accession>
    <name>A0A832UU46_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-layer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022651">
        <property type="entry name" value="S_layer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006454">
        <property type="entry name" value="S_layer_MJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05124">
        <property type="entry name" value="S_layer_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01564">
        <property type="entry name" value="S_layer_MJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="304" mass="34161" checksum="C0DC1756210A4EBE" modified="2021-09-29" version="1">MYLVEKKDKGLFTLPAKELSCENLKVMGSPLATRILETLSKGSSYPKEIAERLGVHEQKVYYHIKNFLKNGIVEVSGEESRQGATAKYYSLTRPSFFVRFKDPVRTGKLSEERKSEFLDPFIKNGSLNANIIIGSPHAHGPERSRSRDGFYGIDVALFLGTFLNYASKTNVRLDTELRSEDLRKNLILLGGPVVNKITERFNAKMPIRFDFKTKDIYSSITKKTYSADETGLIVRFPNPYKKDKHVLVLAGKRYSGTRAATIALVEHLETIEKGNALKPKIFAKVVEGIDADSDGTVDSLEFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UU61</accession>
    <name>A0A832UU61_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015774">
        <property type="term" value="P:polysaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007833">
        <property type="entry name" value="Capsule_polysaccharide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05159">
        <property type="entry name" value="Capsule_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="465" mass="55031" checksum="E94D932FE8FB3B30" modified="2021-09-29" version="1">MKQKKTILFGITNNFFKEQLSLISTELISRGYNVIILTSSRKVNNYFLINNPDIRSIYLPQAGRSLGLKYSDSGLDELFKKYNFNQDQFFFRETKIMGRKKKCLRHYCFPILSYLDRFFEEEKIDYFVNCGEALSNIMMWLVSKKTNVEYFHTTWVGYIDNMHYWDSDLNRISWIKPEFLRKKLSKGDLKIAEDFLSASKKEKKVQGFEPRKVFTYYFFKKYLMYLYNYISTGPARMETYSPPTLANLWISRFFKRLYYRSYYKDFDKNEKYFYFPLHLYYDAIIALTNQEFYRQDEAIKMVAKNIPKDHIIITKEHPVLDGTMPFDMMSAISKLDNVKIVKPHINSHEIIKNSSGVITIASSVGWEAMQYGKPVITLADTFFDYKNLTRKAKNEAELKKLAKQAAEGKLKFNRQDLLQYTYSFVKSHQPNDYFAEDSLSLDRSAKNIRGLADAIEAEIKYRESN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UXY5</accession>
    <name>A0A832UXY5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">2-(3-amino-3-carboxypropyl)histidine synthase</fullName>
            <ecNumber evidence="3 6">2.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dph2</name>
        <name evidence="7" type="ORF">H1011_00630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + H(+) + S-methyl-5'-thioadenosine</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DPH1/DPH2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="3 6"/>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035435">
        <property type="entry name" value="DPH1/DPH2_euk_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022428">
        <property type="entry name" value="Dph2_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="PTHR10762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004967">
        <property type="entry name" value="DPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03682">
        <property type="entry name" value="arCOG04112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="325" mass="36691" checksum="4561C1AABE482083" modified="2021-09-29" version="1">MFEEYSDEIREKNAKRIAIQLPSGLKRKAPEILAELQKIVGEEVELLVLGDTSYGACDLRDIEAEKIGADLMVHFGHASFGVKEVLPTIYIEFFSDQDISPVVEKAAREIKEKRIGLLAVVQFTKQIEKARKILEKAGKKVIVGQSQSRSKHAGQILGCDFTAGTSMEKDIDCFLYIGTGDFHPAGVAMGTKKIVYVADPEKNEIRDMEELKDKLLRVRFAKIEAAKKAKRFGIIVSPKGGQNRLPYARKVASLLQKFGKEAFIVVVDEITPQKLDEFMFDYWVCTACSRIAYDDEAVYKKMITPQEVEIVTGNREWKDYVVDHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UY06</accession>
    <name>A0A832UY06_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Enolase</fullName>
            <ecNumber evidence="7">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 12" type="primary">eno</name>
        <name evidence="12" type="ORF">H1011_00780</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cell surface</location>
        </subcellularLocation>
        <text evidence="7">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="7"/>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 7 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="11">
        <location>
            <begin position="3"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="10">
        <location>
            <begin position="123"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="348"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 8">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="7">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="372"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="404" mass="43671" checksum="6D48BE79B376C4FD" modified="2021-09-29" version="1">MTIKNAIAREIFDSRGNKTVEVQVYSGAFYGRAAAPSGASVGAHEVEAFPEGGAAQAIAVFNRTYKDKLIGTEISYKAVDMLLSETDPDKKNLGGNLSVALSLATARLEALEKEIQFYELFGGSTLPRPVGNIIGGGVHSGKGSPEIQEFLCIPSGAPSFSEAALANSLVHKKAGEKLSSSIQDFTRGRNDEGAWAPKITIDSALQVLTESCQEVSADFGFEIRPGLDVAASEFYSNGKYSYGHKELSPEEQANYMLELVDHYEIFYLEDPMQEDDFDGFAGLLKEVGKKCLVVADDLTVTNSERLKTSIDKKSCNSIIIKPNQVGSLTETEKVIKEANQSRYASVVSHRSGETSDNSIAHLAVGFSAPLIKTGVVGGERVAKLNELLRLEEQESRLEMAELII</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UY67</accession>
    <name>A0A832UY67_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="183" mass="21074" checksum="7EECE9304013B3AE" modified="2021-09-29" version="1">MKKIIAVTGMPGAGKTLACEFAKERGYTVFYVGGLTKEELEKRGLEINEVNEREIRESLRREFGMDVYAQKISEKIDNSDEEVILLDGVRSFEEYEFLRNKYGTDFLMLSIVVSPDLRYERLMSREFRGLTKEECISRDMSEIQNINHGNTIAMGDYYIVNGGSDKNEFKEKVNAVLDRVVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UY90</accession>
    <name>A0A832UY90_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="196"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="248" mass="28720" checksum="FFF34CED255A9F13" modified="2021-09-29" version="1">MANDPFKKLMEWVENEELPDREEILEREKSRVIDQISKANKALGMDTTMEIMKLVYPDTSRLTEVSNKIEEDTSLERLKAITSYLRSFAVAYKNSKKREETLSVHEWSLQKKEEILDRYDAAKKKAKKLGIRKIGEYPKTFLDILRLMRDDKIAEANFLLLQIEGNLMRIGNDLEIFQGAHEDAGALKGFTSGKIIDDLKNDFKSCLKQIDQIYKEAQGEADLAKLDELKQDLKAIMDRIRQIMDQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYB2</accession>
    <name>A0A832UYB2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="382" mass="40191" checksum="5C1AB47D9D4FB21A" modified="2021-09-29" version="1">MKRIFLAFILFFLIFTASAHAQQVTVSLHGPDKVNTDFNVYVALSSMDGFSVASFTVLYNSNSLEFKGVSGGNFSTITPQKSGNLVLINIPDVNGVDGSGSIATLSFGPKVLGTANISIRTIQIVNNLANKAQVSFLGKHSVEILSGGSSVPAYTNPFADSSATPMPEPEEEEETQLSDEEIFEAIESGVDIQDLVPAPDPYFVIEDGETVFGGDDITEEQSTGQQDQSGASGADDVVTGDFTESGSEEGRDGKPAGSGEQKDSKDDSKEGAAKGFPLGLVFGSLLVLGLLGGGGFFVWKKVQSEGGAPASAPSGPSRAPSSAPAKAAPAQAAAKPQYTDQQVEQMLLQNYTPEQQQAYQLMSPEQKAQYIAQYRAQLAHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYC0</accession>
    <name>A0A832UYC0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PHB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043202">
        <property type="entry name" value="Band-7_stomatin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001972">
        <property type="entry name" value="Stomatin_HflK_HflKC_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10264">
        <property type="entry name" value="PTHR10264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00721">
        <property type="entry name" value="STOMATIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="32"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="277" mass="31087" checksum="9049923B04D9A9BA" modified="2021-09-29" version="1">MAVWMLIGIPIGIVLILLLIVMAAPGGSVLNSILFEFKEYERAVVFRFGKYNRIAQPGWNFILPIIESFVKYDMRTESIDIPPQQVITQDRVKVLIDAIMYLRVVDPAKAELEVEEDYRKAIEEHLKGRIRNVVGNTELEDVYGNIDKINSQLKNEIQKLTGGWGIEIIEVELISVIPPEAVLEAMEAQQIAQRYKEAAAEEAETTKIRINAIEAAAGKLSEPALNYLYLQTLKEVADGRASKIIFPMEFTKMAQKLSNGLGGKDSGINKLVEQIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYR3</accession>
    <name>A0A832UYR3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="127" mass="13998" checksum="E72C79E59CCEC9CB" modified="2021-09-29" version="1">MKILTSALVLAIVILISGCTGSVETASSELDSFAECIDNNEVKMFGAYTCSVCAKQKDLFGTSFEKIEEVECHPRGENAQTDWCLELNIEKTPTWMRFENGELVNTAVGFQTLEDLSEFSGCPLEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYV7</accession>
    <name>A0A832UYV7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="208" mass="23475" checksum="9DF6723E0D995C97" modified="2021-09-29" version="1">MQENPAVAIITRIIGGVTLVAISLYLLFSKFSTAINTPQQNNILILFLLLLMLLISRMTVLTKVGVAFIFPILFAVNFVYGTLAALLILWLSTMFFIFLALRPTPIDMFIHKGAGPVVTQTIYLSLWLVLVGISFAVIPSHEVLSNLRVFYLSWLAVYVTFMYFAYRIFTVDPIPQILLNVFASAGFQYLFITFFEASYRSYIIAMAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZI0</accession>
    <name>A0A832UZI0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">(2Fe-2S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="1">
        <location>
            <begin position="2"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="93" mass="10220" checksum="27F48C8F0A7BC66D" modified="2021-09-29" version="1">MIEVHFLNDKKTVKAKEGDSIEALAREVDSSLPFGCRNGLCGTCLVTVEEGEENLSPIAPHESRTLATCGSKEKQRLACQCRIQKGMVKIKWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZI9</accession>
    <name>A0A832UZI9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S17e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps17e</name>
        <name evidence="5" type="ORF">H1011_00515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00511">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001210">
        <property type="entry name" value="Ribosomal_S17e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036401">
        <property type="entry name" value="RPS17e-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00833">
        <property type="entry name" value="Ribosomal_S17e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116820">
        <property type="entry name" value="SSF116820"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="68" mass="7779" checksum="63A15C836C8A9B28" modified="2021-09-29" version="1">MGRIIQTFVKRVGDELLERSPDSYSIDFDKNKVAINEIIESGRLICPSKRIRNRLAGYVSRAVVLRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZN6</accession>
    <name>A0A832UZN6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="449"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="550" mass="62042" checksum="2FDFF41C45FE08BF" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZP8</accession>
    <name>A0A832UZP8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="1">AGPR</shortName>
            <ecNumber evidence="1">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="1">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">argC</name>
        <name evidence="3" type="ORF">H1011_00970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="2">
        <location>
            <begin position="2"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="330" mass="36121" checksum="DFC1DAEFFB339ABC" modified="2021-09-29" version="1">MKAAIIGASGYTGADLIRILDSHPDIEISAITSRKYLGKSVWKAHPSMRNLKLRFTEYTKDVDADVIFLALPHTASMEKVPELLETGVKVIDLSADFRLKDVKIWEKTYGAKHTAPNLIEKAVYGLPELHREEIKKADFVSGTGCEATAGILALAPLQGKADKVIIDVKVGGSAAGSTGNAGTHYPARAGNVRPYAPVKHRHQEEIKQETGFEVSMTAHAVDLVRGILATCHIPNFSEDVSKLYRDFYKDSPFIRITPKDPKFLPNPKYVVGSNYCDIGVVTDEEHKRTVVFSAIDNLVKGASGQAIQCMNLMFGLKEETGLEALPLYPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZX6</accession>
    <name>A0A832UZX6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HMA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="133"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="206" mass="22642" checksum="D477302F62DD166E" modified="2021-09-29" version="1">MSDKEIEVQVDKQSLKSGIFGGLIASMCCISPLVIVILGIGSVTFALAIATYQTWFILAGALFAGTSIWYQLRRKNSCNLKGIKRNKALIITSAVTFAVVYSIAIYGIVPFAAPLVFESNVVELDQETGDLYEMTFTVGNLNCASCESGIKWYLENEVRGVFRAEVTSSGLIKVIYDSDTIDAEGIIESEVFVNYPPRQINENKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZX7</accession>
    <name>A0A832UZX7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">M20/M25/M40 family metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_01745</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="4">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="5">
        <location>
            <begin position="177"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="393" mass="43712" checksum="EA1601BF4CE2DF40" modified="2021-09-29" version="1">MNWDLNFERLEGDLCSLIEIPSVSGNEQAISNFVRDTLKKSGLKPKQDKMGNVIIQINGKHEGKHVILNGHLDTVPPGKGWKGDPYKARQANGRIYGLGSADMKAGLAIMMELSRIFHSLKRNFCGKVTFAFTVGEEVEDHKRHGAYHITKKLKGNFAMVLEPSQQDDSKNICVKVGNGGRCILNVKIHGKAAHSGRPFLGVNALEVGSLVVNKIRKEAPKIKEFKIKELGVSFRPGFSVTKMSVDDSPSNVIPDYCELTIDRRTVPGEERTEIITQVRSILDSVKKESGIEFKYELKLLGYRRPVLMPLDSKLLKTLMEKVEKRYSYTPRLLFSLGTSDAGYFEKSGTPTLSFGPGDLHHIHKANEHVSKAGLRAYALICMDMISDVCEVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V025</accession>
    <name>A0A832V025_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901576">
        <property type="term" value="P:organic substance biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044272">
        <property type="term" value="P:sulfur compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="7"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="311" mass="33470" checksum="9AF23192DA75AD62" modified="2021-09-29" version="1">MSSEAFEATRTGYGRGLLAAGKKNENIVSLEADLGASCKTAEFKTEFPERSFNLGISEQDMICTAAGMAAEGKIAFAATFSIFTERAFEQIRNSVARQNLDVKIMGSHSGLHTGEDGSSAQTVEDISIYRTLPNMNVVVPADFVEGEAATLAAAETSGPFYLRFGRNKTPVIYDENYKFELGKGSILKDGSDITIIACGVLVSESLKAAEILEKDGISARVVNMSSIKPIDSELIEKCANETELIVTAEDHSIIGGLGSAVAEVLSERRPTRLVRIGVQDVFGESGSPEELYKKYGLDAESISEKLKEEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V031</accession>
    <name>A0A832V031_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000002">
        <property type="protein sequence ID" value="HIJ99252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013373">
        <property type="entry name" value="Flagellin/pilin_N"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02537">
        <property type="entry name" value="arch_flag_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="165" mass="17962" checksum="B5247AB6B55C5E8F" modified="2021-09-29" version="1">MRFPKFFSSKKGITPIISVILLLMMTIAIAGLAYTFLQRMQGTIQTSSENTSLELLGGLNVQLKVEGFVANCSASTDKVNITIYIRNAGTEQAEKLQLFVDDALQSGMANDTLAAGTVTSYSGGVLDDVSCSEWVNKTKEVRISSRETSAEKLIKFTCTYSSYLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0A2</accession>
    <name>A0A832V0A2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">lipA</name>
        <name evidence="8" type="ORF">H1011_02785</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="49"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="301" mass="33740" checksum="544BD546A5B0C577" modified="2021-09-29" version="1">MADYKKKPDWFKIKLPTSTRFSKTQDIVKSSGVATVCEEASCPNISECWTQGTATFMIMGDTCTRACRFCNVKTGIPKMPPDSKEPENLAEAIKEFGVEYVVITSVNRDELPDGGSGHFAKCIRAIQEKCPSTLVEVLTPDFFANEKQIRNVVEAKPNVYAHNIEVVKELQREIRDPRASYANSLETLRTVKRIDRKMPTKSSIMVGVGETQEQVLQAMGDLRDAGVSFLTVGQYLRPTENHYPVNEFIHPDVFKFYEEEGTKIGFDYVASGPLVRSSYKAGEYYIKNMLDGGNGKEEGFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0A5</accession>
    <name>A0A832V0A5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">DNA polymerase II large subunit</fullName>
            <shortName evidence="11">Pol II</shortName>
            <ecNumber evidence="11">2.7.7.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Exodeoxyribonuclease large subunit</fullName>
            <ecNumber evidence="11">3.1.11.1</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">polC</name>
        <name evidence="13" type="ORF">H1011_01165</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 11">Heterodimer of a large subunit and a small subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the archaeal DNA polymerase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="11"/>
    <dbReference type="EC" id="3.1.11.1" evidence="11"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000738">
        <property type="term" value="P:DNA catabolic process, exonucleolytic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00324">
        <property type="entry name" value="DNApol_II_L_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004475">
        <property type="entry name" value="PolC_DP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016033">
        <property type="entry name" value="PolC_DP2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42210">
        <property type="entry name" value="PTHR42210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03833">
        <property type="entry name" value="PolC_DP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016275">
        <property type="entry name" value="PolC_DP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00354">
        <property type="entry name" value="polC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="11" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 11" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolC_DP2" evidence="12">
        <location>
            <begin position="5"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="HIJ99417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="1165" mass="131251" checksum="10D336033CED2EF9" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0C6</accession>
    <name>A0A832V0C6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminopeptidase P family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_01400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="5">
        <location>
            <begin position="8"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="143"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="337" mass="37874" checksum="E3C42581A2D27431" modified="2021-09-29" version="1">MIGKEQTERALGIFDEQGIDSLFLMNIQAKDPFFYYFTGASGFESSLVLIGEEPVIYTPGFEMERASEESWIKDVREFSTKNTLKDIKKIVGNNIVGVNWKFLPLRMQEKLQKAGIKTKDVSEALLDLRQYKTKEELGLIEKAVKATKQIIEKIDTSLPGNEIRAELLSQYAMKDMDEFYRAIVAYDADSAVPHYRGVSKPGKQCLLVDTGGSYKGYGADITRTFLLEPEKELKEIYSIVEEAQKAAIVLIEPGARISDISKVADDIIEKAGYKMVHSLGHGIGLEVHERPNIRTGSDEVLEENMVFTLEPAIYIKGKYGVRIEDNILVTKKGCKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0D6</accession>
    <name>A0A832V0D6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="5">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">glmS</name>
        <name evidence="8" type="ORF">H1011_03020</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="5"/>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5 8" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="6">
        <location>
            <begin position="2"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="7">
        <location>
            <begin position="267"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="7">
        <location>
            <begin position="423"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="5">
        <location>
            <position position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="573" mass="63094" checksum="A8139B451CDC9C7A" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0J4</accession>
    <name>A0A832V0J4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP-dependent dephospho-CoA kinase</fullName>
            <ecNumber evidence="3">2.7.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Dephospho-coenzyme A kinase</fullName>
            <shortName evidence="3">DPCK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_02045</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3'-dephospho-CoA + GTP = CoA + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61156"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme A biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP-dependent DPCK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="3"/>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00590">
        <property type="entry name" value="Dephospho_CoA_kinase_GTP_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007164">
        <property type="entry name" value="GTP-dep_dephospho-CoA_kin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40732">
        <property type="entry name" value="PTHR40732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04019">
        <property type="entry name" value="DUF359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DHH" evidence="4">
        <location>
            <begin position="173"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="5">
        <location>
            <begin position="394"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="493" mass="54886" checksum="32ACD1626E350CF0" modified="2021-09-29" version="1">MLTDFKIAEETRKDLKSPIGELTEELPTSGDGLIAVGDVTTLRLLKEGVTPDICVIDYKAEREALSEEDIKTLKSLDVREIKATNNAGEISLSAWRAFEDALKNTPAKIVIEGEDDLLALVALFLAPDGSRVVYGQPDVGTVMFEVSDRIRQKYAEVLIHGKGREFLNAIQGKVVIVHDSDADGACSAIVFAKYLEDRKIEVVLMESSDPLIHSNTKKEIRKEKAGSLIVLDLGSEAYDSLKELSEEMHVMVLDHHKVVGSPDFGKTLILNPHLFNIPDNVVGPTSYLSYVICQELDWVAAIGTIADKGFYPAEELLKSVKKRYKVDFERLSQMFEAGAVLRKLAETRDEVRNAESPEELEKSETLISFEKEYLQELERLKKLHESEAEELAEGRILLFDFTSEYRVRGMVSNMLQSMYPEKSIIVAEKVGQHYYFSMRAGGQNVDLVEIIKYAIDGLADANGGGHTKAAGARVMAGDRDKFINGFVGKFKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0M3</accession>
    <name>A0A832V0M3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="387" mass="43866" checksum="4542DAABF7CCEB7B" modified="2021-09-29" version="1">MQENPFSDSVPSHLAIAATVYTKPLLDLEKLSDTNRSKLFLVIGDYGNGKSHALEKLKNDLNIKKKDTLAVYTSAFATKSLRRIYEQVCAELITGKIEKFEKGSEVRLAMVSKGIPSKIIEIFYEGNHLKNLDGIAECLPFGKVVNSSADAVDFICAISLLVDQLVLLIDDIEEASVLERAERKAFFGYIRALYDQAVRKDLNLSVVLAMTYKKVELLESDRPDLLERTDHFIDFVKPSKKEFYEMVKRRLEVSGLGNYSFTEDTLEATWEGFPSIRSMFNLLRDSLDKAEKEGVEEITSITIPQKKKSEMASALQRAAYKPADDEIVTALRKNDGLYVEEIVSKTKMSSSWIRHRLADLVRGNILRKEQEARNKPAKYYLVKGKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0W8</accession>
    <name>A0A832V0W8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S8e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps8e</name>
        <name evidence="5" type="ORF">H1011_03500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00029">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020919">
        <property type="entry name" value="Ribosomal_protein_S8e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_S8e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_S8e/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="PTHR10394"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="127" mass="14228" checksum="302FB4ACD6965AD8" modified="2021-09-29" version="1">MAIIQERPKRKKTGGRYIAYRKKRFHALGRDQIEVRIGAGKTQSVRGRGGNLKSRAITVKEANILDLKTKKFRKAEILSVSDNKANQHYIRRNTITKGAVIETSAGPAKVTNRPGQEGYINAILLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1C2</accession>
    <name>A0A832V1C2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TIGR00269 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_00190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000001">
        <property type="protein sequence ID" value="HIJ99231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034227">
        <property type="term" value="P:tRNA thio-modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000541">
        <property type="entry name" value="Ncs6/Tuc1/Ctu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035107">
        <property type="entry name" value="tRNA_thiolation_TtcA_Ctu1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004976">
        <property type="entry name" value="ATPase_YdaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00269">
        <property type="entry name" value="TIGR00269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ATP_bind_3" evidence="2">
        <location>
            <begin position="50"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="304" mass="34605" checksum="D96B0B8231CB4417" modified="2021-09-29" version="1">MNCDKCQNPAVAHLRYSDIRLCKNHFIGLTTDRIRKTINKNKFFERGDRVAVAVSGGKDSIVTLRELHDISKKRGIEIVGVTIDEGIADYRPESIDIAERTYKELGVDYTILTYKERVGKPLDKIMEKPDINRACEYCGVFRRRLIEDGAREMGADKIATGHNLDDEAQSIFMNYIRSDFPRIARSGPKTANKKGFIPRVKPLCNIPEKEVGLYAILKGYEIHEDECPNAANAFRLNIRDHMNLIEDKYPGFKFGIYNSAENLRNILADVNIEKNTLKKCENCGQNTSGKICKFCELKAYANKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1S5</accession>
    <name>A0A832V1S5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="195" mass="21283" checksum="5C0518B549D953A4" modified="2021-09-29" version="1">MEHKEPKDRGNLILITSLILFLVISVFLVLPEKNQTPPDIFTCQDQETDFNVNISDCRAVQIIPSEAALVGMLLNSQVNGITLLMDPNKSCTGCHQGGYIGLAVGTVQKPAQALHLPVAFAYTEQWFKTPGIRVSSPSDASTRNPIIWFNPHNQSENTIQVWPDGLITINAKDGHGMQAASCKIAITLIESVLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2E0</accession>
    <name>A0A832V2E0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DsbA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutaredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="33"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="273" mass="30059" checksum="E7275CBC76473696" modified="2021-09-29" version="1">MAKGDKTITVKFKEATLWKAATAVLAILLIISFQSGGGLEVQEEGTVAAGTIKIIELSIDDDPILGNDKAKVTIIEFSDFQCPFCNRIWADAIQGIKSNFIDDGSVRLVYRDFPLNFHPSAGKAATAANCAEEQGQYWEMHDKLFEGQQSDWGYYVQEERKYLALEDAMPFFRQYASELGLDTDNFNDCLDSDKYDSEINKDLIAGQTAGVTGTPSVFVMMSKKKAPKAELQALDDGSNIFYFETSDGKYAGIQVAGALPYGAFEQIINVMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2F1</accession>
    <name>A0A832V2F1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mrr_cat" evidence="1">
        <location>
            <begin position="85"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="271" mass="30852" checksum="2C7223B94BD42E8E" modified="2021-09-29" version="1">MVQITKADGSCTVFKKSKIVGTCLRSGLSKEIAVKIADELDRGVYEGMRTREILKKTLSLIDKYESKQHKYKYNLKQSIAELDPEHHQFERFITHLFRELGYKTRWNVIVQGEVIEHQIDSLLEKGGRKLLIECKHHINPHRLTGLGTVLTTWAVLDDVRKGPNPYNNIWLVNNTKFSNHAKKYSAAKKMKLIGWNFPKGGSLPELIEKTQAYPANIISMSAKERKIIMANNILLAKELASCKPDSLSKKTGLRKSRAEELVEKAKTLLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V2G2</accession>
    <name>A0A832V2G2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="214"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="408" mass="45895" checksum="5AEFAE2A88E62CDE" modified="2021-09-29" version="1">MKLLMVQHHYYPSLGGGQEYAKLLSEGLVKKGHKVTVFTTNSLTNEDILSLSFTPPFISRKKKIKPLKSKETVGGVSVKRFPVKGRFYSFNSIPEMFSSMDDFSDYDIITSYGFNLLSSFEACRKAKKQGKPFVLNGVDVLVPKTLPLPARALKWIYDLSFGRYLAKNSDYIISFTEDQVKDYVKRGVDESKIGIVPPPLILKDYSSKVSESFLKRHGIKKGDKLLLYAGRITEHKGIQDVIESLPAIRKKVPTIKFFIAGGDYGYTEILQRLIKKKGVEDCVFFVGPYKAREKELVQFFAAADVFVLPSNMEGFGIVLAEAMACGTPCIAYNIPAVREVISDRKNGYLVEDKEDLKNHIISMFSNPTELKRMGENGKESVKRLSQSAVVSNLESIYKKVLNSKREKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3K4</accession>
    <name>A0A832V3K4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="168" mass="18017" checksum="15965464CA97D12E" modified="2021-09-29" version="1">MGRLVLATLVLTVIIAGCTGQIDTSELSSEIRDIVSGIENISDMIPENISAMFPDNLSRIQEIINETSEAIENITADIISGAEESPCTTSGTTLVYLKGIYEAEGGAYKAKFEVFKDNSTEIKYIVSGTTEGVNSVTIQVNEILVRSTGGGEVNAYIFGENQTCVYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V3L7</accession>
    <name>A0A832V3L7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="64" mass="6810" checksum="FE397CA6E8D7064A" modified="2021-09-29" version="1">MAIKHGKVWESLLVAGSIIFAFGIIWGSLLLAKEFTEAQGALVLIIIGTVLLILSETSLLSKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V415</accession>
    <name>A0A832V415_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="34"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="276" mass="30237" checksum="A3B28701F4FE2328" modified="2021-09-29" version="1">MNEIVFLGTGGGRWSTITQKRATGGFRLNLEEMNLAVDPGPGYLARSKQFGQDPQKVDAIFISHAHVDHSTETNVAIEAMTRGLTEKRGSVIGSQSIFEKVEENGPIISDFHKRQVFECLNMAREDVAVVNGVDFLFTGAEHKDSTTIGFKMKAKCGTISYTSDTSYFDGLSEQFKGTDVLIMNATRPGNERIPYHLCTDDIIKLVDAVKPKLAIMSYFGLRILKVGPIGEAKQVNDTTGIRTIAAEDGMVISMKEHDQSTLKTFGSPKPIKITGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V423</accession>
    <name>A0A832V423_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="8">SHMT</shortName>
            <shortName evidence="8">Serine methylase</shortName>
            <ecNumber evidence="8">2.1.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glyA</name>
        <name evidence="11" type="ORF">H1011_02420</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.-" evidence="8"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5 8" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7 8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="10">
        <location>
            <begin position="7"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="124"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="352"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="8 9">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="HIJ99654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="415" mass="45763" checksum="0522BA117BC4BCD8" modified="2021-09-29" version="1">MVNLESLKDGDPEMYNLIVKETSRQNSGLELIPSENFVSKAVLEAMGSILTNKYAEGYPGKRYYGGNQYIDLIEQIAIDRAKSLFGAEYANVQPNSGSPANMAVYFALMEPGDKLMGLELSQGGHLTHGSPVNFSGKLYSASSYSVDKETEMIDMDVVRKYAEKEKPKILLSSTTAYPRELDFKEFSEIAKDIGAISMADIAHIAGLVIGKVHQDPFPFTDIVTTTTHKTLRGPRSGLILCKEEYGKAIDKAVFPGMQGGPHEHIIAAKAVCFKEAATPEFSEYAKQIVKNAKKLSESLIEHGFRLVTGGTDNHLILIDLTNKGITGKEAQNSLDEAGITTNRNTIPFEPRSPFDPSGLRLGTPAITSRGMKESEMEQVAGWINRVIENHGDSSLKEKIREEIREFCKEFPLYPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V448</accession>
    <name>A0A832V448_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease P protein component 1</fullName>
            <shortName evidence="6">RNase P component 1</shortName>
            <ecNumber evidence="6">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Rpp29</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnp1</name>
        <name evidence="7" type="ORF">H1011_02650</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Consists of a catalytic RNA component and at least 4-5 protein subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="6"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00754">
        <property type="entry name" value="RNase_P_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023538">
        <property type="entry name" value="RNP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00538">
        <property type="entry name" value="POP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="SSF101744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="92" mass="10267" checksum="4D263977D7F91E1C" modified="2021-09-29" version="1">MISEKNIVQHELVGLDVEVLECTDLSKKGARGTVIDETQSTLILSDTKGESKRIPKAECTFRFLLNGDTIDVVGSLLLGRPADRIKKRLKKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V4A4</accession>
    <name>A0A832V4A4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">TATA-box-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Box A-binding protein</fullName>
            <shortName evidence="4">BAP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">TATA sequence-binding protein</fullName>
            <shortName evidence="4">TBP</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">TATA-box factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tbp</name>
        <name evidence="5" type="ORF">H1011_03395</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00408">
        <property type="entry name" value="TATA_bind_prot_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000814">
        <property type="entry name" value="TBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10126">
        <property type="entry name" value="PTHR10126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00352">
        <property type="entry name" value="TBP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00686">
        <property type="entry name" value="TIFACTORIID"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <feature type="repeat" description="2" evidence="4">
        <location>
            <begin position="100"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="182" mass="19995" checksum="23C68C808FD93BCA" modified="2021-09-29" version="1">MKIENVVASAAVDAEMDLDKIAATLDNAEYEPEQFPGLVLRLKKDVPKGIPKAAILVFSSGKMVCTGSKEIRLVKVALTETLKQIRKCGIKVKGEATIKIQNIVASSDLKSELNLDKIAFTLENTEFEPEQFPGLVFRVAKPKVVFLLFRSGKIVCTGAKKVIDVRRGVEVLVKELKKAKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V4D3</accession>
    <name>A0A832V4D3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_03720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="238" mass="27023" checksum="3E3C32A9D858FA4E" modified="2021-09-29" version="1">MARRKKETKQELEFGIIVFALFIITLLLTFVWYFSALDTAKTDALSKIHSFKSPCQDLAALSSDCSIVNDFYQIQYDAICNDKMDAQLRELKKKVETSQNLIEVLYIKKVQELRPLEAINQDLVTIGEVLLGTEYYLEKMADKQEIMYDTGILLGNCQMNTEKLMTAASCDLSRLELLLPLSGRELSQDAFQKAKDAFEQENYLAAISYTTAAAAFQDGITRDQYSELLNSPSWTVCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V7X3</accession>
    <name>A0A832V7X3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoate--protein ligase</fullName>
            <ecNumber evidence="4">6.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">H1011_00465</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-lipoate + ATP + L-lysyl-[lipoyl-carrier protein] = (R)-N(6)-lipoyl-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10500"/>
            <dbReference type="Rhea" id="RHEA-COMP:10502"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.20" evidence="4"/>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00537">
        <property type="reaction ID" value="UER00594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019491">
        <property type="entry name" value="Lipoate_protein_ligase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10437">
        <property type="entry name" value="Lip_prot_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lip_prot_lig_C" evidence="8">
        <location>
            <begin position="13"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="HIJ99280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="96" mass="10423" checksum="93B87CB50B8C5D9B" modified="2021-09-29" version="1">MGSILKKQFKVAGGKLLKASFSVDDGKLKDVKITGDFFLYPEEAIDGLISVLNGVEFAEESIAETISEYLKVNKAEFVGASPQDFAKLFTDEPEAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V895</accession>
    <name>A0A832V895_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Flap endonuclease 1</fullName>
            <shortName evidence="10">FEN-1</shortName>
            <ecNumber evidence="10">3.1.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Flap structure-specific endonuclease 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fen</name>
        <name evidence="13" type="ORF">H1011_01390</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Interacts with PCNA. PCNA stimulates the nuclease activity without altering cleavage specificity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="10"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017108">
        <property type="term" value="F:5'-flap endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043137">
        <property type="term" value="P:DNA replication, removal of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00614">
        <property type="entry name" value="Fen"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023426">
        <property type="entry name" value="Flap_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019973">
        <property type="entry name" value="Flap_structure-sp_endonuc_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006086">
        <property type="entry name" value="XPG-I_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006084">
        <property type="entry name" value="XPG/Rad2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006085">
        <property type="entry name" value="XPG_DNA_repair_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11081">
        <property type="entry name" value="PTHR11081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00867">
        <property type="entry name" value="XPG_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00752">
        <property type="entry name" value="XPG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00853">
        <property type="entry name" value="XPGRADSUPER"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00484">
        <property type="entry name" value="XPGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00485">
        <property type="entry name" value="XPGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03674">
        <property type="entry name" value="fen_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4 10 13" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 10" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XPGN" evidence="12">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="XPGI" evidence="11">
        <location>
            <begin position="140"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-domain" evidence="10">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="HIJ99460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="336" mass="38114" checksum="CF6BEBF03B06832E" modified="2021-09-29" version="1">MGVNLRDILERDEIRLDSLAGKRVGVDAFNTLYQFLSTIRQKDGTPLMDSKGNVTSHLSGIFYRNVRLLEHKLLPVYVFDGEPPSLKEDTIKERKERKEEARKKWRAAIVAGDLDRAKTYSQATSQLDKKMIDESKKLLDVLGIPHVQAPSEGEAQAAYMCKKSEINVVASQDYDSLLFGSPILVRNITISGKRKVPRRNMYVRVHPEKMVLQEQLERLGISLENLIEIAILTGTDFNPGIKGVGAKTALKVIKKDGFEAAIEKYDFQVDPYAVKKIFTNPETTDDYKLSWGFPDEEKAIELLHEKHEFSRERITNALSKLEEATGSRDQTSLDSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8E9</accession>
    <name>A0A832V8E9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Replication factor C small subunit</fullName>
            <shortName evidence="6">RFC small subunit</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 6">Clamp loader small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rfcS</name>
        <name evidence="8" type="ORF">H1011_01770</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heteromultimer composed of small subunits (RfcS) and large subunits (RfcL).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the activator 1 small subunits family. RfcS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000010">
        <property type="protein sequence ID" value="HIJ99535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005663">
        <property type="term" value="C:DNA replication factor C complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003689">
        <property type="term" value="F:DNA clamp loader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01509">
        <property type="entry name" value="RfcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023748">
        <property type="entry name" value="Rep_factor-C_ssu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013748">
        <property type="entry name" value="Rep_factorC_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08542">
        <property type="entry name" value="Rep_fac_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="38"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="323" mass="35991" checksum="0A10AB4B3A7B520E" modified="2021-09-29" version="1">MEFNTAIWTEKYRPAVLSEVVGQKHIVERLSAFAKEKTLQHLLFSGPAGTGKTTCALALAKETFGDNWQGNFLELNASDERGIDVVRNKVKDFARTKALGDVPYKIIYLDESDALTKEAQQALRRTMENYTHTCRFILSCNYSSKIIDPIQSRCAIFRFGPVERGELEKRLKFIAEEEKLSVDAKGMEALLEISNGDLRTAINLMQSVASSGESISEESVYTISARTKPGEIEDCLKLAMNGGFKEARKKITAMMIEKGVSGGDVIRQMHRALLSMDEIPENALAGLLDRLGEYDFRITEGSNDIIQINAFLAQLYKTGKDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8G1</accession>
    <name>A0A832V8G1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000011">
        <property type="protein sequence ID" value="HIJ99550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="366"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="387" mass="43623" checksum="BF0F72D452A77442" modified="2021-09-29" version="1">MADDDKSVKTLSTILNVIAIIVLIGYTYTLISSGQAELDLSFSQTQVSLMFLALMGSGVMFAYYGKSDKYGAFGTNIAVMILIMSMTAIFVTPRTQLLLPLGILGLVELGIWFWGKKKTEYGQRRAQEKTEVALAKGVDNKEARLIKGVTKTVNKLISSAMEIEEEIDKVIDFLEENGDLRTRINAQMGADKDITRLLAQVKEHIEGDELPQHEELADLVGILKELKIGEEELKEHQEKLILISMLAPLIQAMEKGEDREELEAVEHKIFRRVMRLQKKERTEEGEEAQAVGYEIQLLHHVETAVVTTENYLRNPETNKRTKKDSKTGTKLVEEAGKLSGMITGLIGKYEEQLKLMNREIKKEGKLIRVERREERKGAGESPEAEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V8P2</accession>
    <name>A0A832V8P2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="1">6.3.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="1"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="PTHR23407:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="190" mass="21653" checksum="18663BD142B491B2" modified="2021-09-29" version="1">MKKNLRKKHLQKRSEVPIPTVLKKSEVIGEKLLQLKEISESSKIMIYSSLESEVDTAVIIRSFLKSKKEVYLPRTEIKTRTMEAVRIKKFPGEVETASFGILEPKKELPACESIREIDLVIVPGVAFDERGNRLGYGFGFYDRFLAEIRAPKIGLSFESHILDTIPTESHDIKVDKIVTELRVIDCSNFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X500</accession>
    <name>A0A832X500_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nascent polypeptide-associated complex protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nac</name>
        <name evidence="6" type="ORF">H1011_00935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Contacts the emerging nascent chain on the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Interacts with the ribosome. Binds ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAC-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00814">
        <property type="entry name" value="NAC_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044034">
        <property type="entry name" value="NAC-like_UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038187">
        <property type="entry name" value="NAC_A/B_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005231">
        <property type="entry name" value="NAC_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002715">
        <property type="entry name" value="Nas_poly-pep-assoc_cplx_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19026">
        <property type="entry name" value="HYPK_UBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01849">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01407">
        <property type="entry name" value="NAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51151">
        <property type="entry name" value="NAC_AB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="NAC-A/B" evidence="5">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="109" mass="11768" checksum="CC66BADB8C9C39FA" modified="2021-09-29" version="1">MLPNLNPKQLEKAMKKMGMSVDEIDAEEVLIKLRDGSQITISDPQVAKMNMQGQDSFQISGTVSEGQSEATESDIEMVVQQAGVSEDVAREALKSSGNDIAKAILSLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X509</accession>
    <name>A0A832X509_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="6">IMP dehydrogenase</shortName>
            <shortName evidence="6">IMPD</shortName>
            <shortName evidence="6">IMPDH</shortName>
            <ecNumber evidence="6 11">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 13" type="primary">guaB</name>
        <name evidence="13" type="ORF">H1011_01095</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 11">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6 11">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 10">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="6 11"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 11" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2 6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7 11" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 6 8" id="KW-0630">Potassium</keyword>
    <keyword evidence="6 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="92"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="12">
        <location>
            <begin position="151"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="6">
        <location>
            <begin position="336"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="6">
        <location>
            <begin position="359"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="6">
        <location>
            <begin position="383"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="6">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="246"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <begin position="296"/>
            <end position="298"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="300"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="HIJ99404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="474" mass="50513" checksum="44DB9B95B40730E7" modified="2021-09-29" version="1">MDARTGLTFDDVLLVPRRSAVKSRKDVNVSTKLSRRIPLSHPIVSSNMDTVTEVEMAISMARSGGIGILHRFLPAEEQAKMVSRVKRAASYKIDTPYTTGADAKITELQSFMKEKGVHSILVVDSENKLLGIVTSRDLRFIENGSKVSSIMTPREKLICGDPEISIDKAKGLLSENRIEKLPLVDSNNTLKGLITAKDILNITQRPHASTDDKGRYLVGAAIGVKEGYLDRATTLVEAGVDALVVDVAHGHSDLAIDTVNTVKEKFPSVDIIAGNVATAEGTKDLIDAGADAIKVGVGPGSICITRVVTGSGVPQLTAIIDCAEEAAKSKIPIIADGGIRTSGDISKALAAGASSVMVGNLLAGTEESPGKPLMKDNRKVKVIRGMAGYISNMSKLERDHIHSDALDIVPEGVEGYVPYRGHTSDILNQLIGGLKSGISYCGSHNIEEMQKKSKFIRVTSAGKAESKSHDISKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X550</accession>
    <name>A0A832X550_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="224" mass="24229" checksum="E323B50AC1416209" modified="2021-09-29" version="1">MKTSTEKIQMRALRSFGILIASFIIFFGLLASVQGYNIEKVTQKDVLLDALEPMFSNMLEEECAEAGEFKDSCIAQASSSINLSEKIDGLYMASVKIPLIGAISLYSLNSIASASQGSGLMVAAAGILLILFILKDKLKILKILGGLFVSLSVATYGGAFLVEKAILPRLLSGQLSAVVSLADFFSSQLLNFQFFVGKLFLIAGISVYASYFLIRKYLFSEVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X580</accession>
    <name>A0A832X580_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018645">
        <property type="entry name" value="DUF2072"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09845">
        <property type="entry name" value="DUF2072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="134" mass="15328" checksum="665C941A1EA0D610" modified="2021-09-29" version="1">MHKCLKCGEKFEEDDVPVVSGCSCGGRMFLLLRGDEDEERADEIYEELSEKIEEIKELPETQEEKPEKSPDKTPETENPKFGVETIRIKRPGVYEINIEALMKGRPIVVRQREGSFIISLPSIFGRETEIVLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832X5L4</accession>
    <name>A0A832X5L4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CDC48 family AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_03745</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. CDC48 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005938">
        <property type="entry name" value="AAA_ATPase_CDC48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="SSF54585"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01243">
        <property type="entry name" value="CDC48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48_N" evidence="4">
        <location>
            <begin position="11"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="CDC48_2" evidence="3">
        <location>
            <begin position="111"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="245"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="519"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="762" mass="83932" checksum="5F7A5C19E714C5B3" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFN2</accession>
    <name>A0A832XFN2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exosome complex component Rrp4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rrp4</name>
        <name evidence="6" type="ORF">H1011_00730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RRP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008143">
        <property type="term" value="F:poly(A) binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00623">
        <property type="entry name" value="Exosome_Rrp4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026699">
        <property type="entry name" value="Exosome_RNA_bind1/RRP40/RRP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023474">
        <property type="entry name" value="Rrp4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21321">
        <property type="entry name" value="PTHR21321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0271">Exosome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="79"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="232"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="275" mass="29930" checksum="FD74EA039307C0AF" modified="2021-09-29" version="1">MQEIAEIKTKTKGEKMTLKIKNRDIVVPGELLGTGDLLLGEGTYKRGKNVHSNILGLVDSKENFIKVIALNGRYIPKPKDVVIGVVKDISFSHWSLDLNSAYGGVLTVANGTDYFVNLDDEDISKIYGIGDAIVAKILNVSKAMNAGLTMKDRGLYKLSGGRIITITSTKVPRVIGRKGTMVQMIKDMTGCKITVGQNGRVWISGDNEELAVEAIKLIESKAHTPGLTENIRKFLEKSTGNKSSLKPKPVGSKEPEAESVESKEPEAEESKEAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFR0</accession>
    <name>A0A832XFR0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Adenylosuccinate lyase</fullName>
            <ecNumber evidence="5">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_01120</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="5"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADSL_C" evidence="9">
        <location>
            <begin position="360"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="443" mass="50377" checksum="0384951E5C74F49F" modified="2021-09-29" version="1">MLARYLENQHTTEEMEKIFSDENILEKWLSIEAALAKAQASVGNIPKKAADTIGKNANLKTITLERVEELEEELQHRILAVSTALAEKSGEYGKYVHLGATSYDIIDTGWALIFAEGLGIIEKRLKNLRLVLLDMAKQYRDLIIIGRTHGQHAVPTTLGFKFAIWSCEIDRQLDRVEKSRKNILFGKMTGAVGTGASFGKNATKIQDLVMKDFGLKSPRATTQVIQRDRHAEVIFTLVMIGQTLQKISTEIRNMQRTEVGELEEPFKKGKIASAGMPQKRNPWRSERIAGIVRYLRSNIMPALENIPLEHERDLTNSSCESIIFPETFILTDFIVEETIQIMQGLNVYPDKIHRNIMMTKGRFMSEAVMLKLVEKGMERSKAHEIMKEASMESSKKDIEMMEVLKKKPKIRELLSEDELSEVLDPKNYIGSAKTQIDKIIRTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFT7</accession>
    <name>A0A832XFT7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="48"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="161"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="317" mass="35383" checksum="E7B90717230E1BBB" modified="2021-09-29" version="1">MKAVLGPYPPPYAGTELVVREEFEELGRDGFLIGTSIIPVELDDRILIRRSRFVINGPALIYQIMRRRRQIDSISAHFATTFGYVARIAKILFDIPYTVTCHGTDALINLKRKPHSYFTRKALQGADTVYAVSESVKDSLLIGGVPESKIELVHRKIGKAFSGKKVKRKNQVIFVGSVHHIKGLDTLLTAFAEFSKKNTNFSLKIVGRIADPHYLKLLKNLSEELRISEKVHFVGEMPHDHLPRYLNESKLFVMPSRSEGYGRALDEALSCGLPAVATNVGGLPEVAKGRNCILVEPELPGQMANAMQRALKGREHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG05</accession>
    <name>A0A832XG05_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="1">
        <location>
            <begin position="33"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="226" mass="25386" checksum="AD1E6624ABD7A351" modified="2021-09-29" version="1">MSTEEQEEHYYKEKTKIPLQLVEVYALIKGTELKLLSSPPVFSWRKIDKGSLILAENMLIPEGQGKLLDMGCGYGVLGIFAALQNPLLEVQMVDSSERAVYLSKKNIRKYGLGSRVTVIQGDLFDKLEDKDFDTIVSNPPYSAGKDIVGSLIADSPAYLAEEGTLQIIGRHSKGGKMYREHIKEAFAYEFEFGIQSGFRIYLGSKKDIPELREDKESILESYSTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG27</accession>
    <name>A0A832XG27_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="2">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_02855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="3">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="91" mass="9576" checksum="794A2B4CA2B68F84" modified="2021-09-29" version="1">MENQRAKQGDRVSVDYTLTVDGKVIDTSKGRGLFSFTLGAGEVIPGFDDAVTGMSIGETKTVEISGDKAYTTGDLAGKVLNFELSLKGIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG63</accession>
    <name>A0A832XG63_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="92" mass="10467" checksum="B428D2B2CF1F576D" modified="2021-09-29" version="1">MIKVKIYTTPTCAYCTSAKEFFDKNDIKYEAIDITKDAEGMKWMQERSFQGVPVIVLGEGDKEEILQGFNEEVQAQIEEELGMRSDSDKGYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG67</accession>
    <name>A0A832XG67_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Anaerobic ribonucleoside-triphosphate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008998">
        <property type="term" value="F:ribonucleoside-triphosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012833">
        <property type="entry name" value="NrdD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13597">
        <property type="entry name" value="NRDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="610" mass="68189" checksum="866B1C589FDD4AD8" modified="2021-09-29" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XG76</accession>
    <name>A0A832XG76_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="3">HMG-CoA reductase</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">H1011_03690</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00644">
        <property type="entry name" value="HMG-CoA_reductase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004553">
        <property type="entry name" value="HMG_CoA_Rdtase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="PTHR10572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="SSF55035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="SSF56542"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00532">
        <property type="entry name" value="HMG_CoA_R_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01192">
        <property type="entry name" value="HMG_COA_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="371"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="381"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="397" mass="42043" checksum="F2D35B4A2927D07B" modified="2021-09-29" version="1">MTSSRIPGFYKLSPKERLDAIVEFSGLSEEDRKVLEKSFLTVEQADKMIENAVGSLPVPLGFAANFLINGKDYLVPMATEEPSVIAAASNAAKICRVKGGVKSETTSPIMIGQIHLSGVSNQDEAERKILSEKERIIETCNSCDSTLVRLGGGAKDLEIRKLEKTIVVHLLVDCRDAMGANAVNTMAEKIAPVLEELSGGKAVLRILSNLAVHRLVKSSAVFDKEELGGEDVVDAIVEISEIAKTDIYRASTHNKGVMNGISALVLATGNDTRAVEAGVHSYAGRGKSYLPVTSFRKNSEGDLVGELEIPMAVGIVGGATKNHPIARANLNVLGVSSASELAEIIGAVGLCQNLAALKALASEGIQKGHMKLHSKKAESEKTGTTSGLNISNSKEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHD2</accession>
    <name>A0A832XHD2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="235" mass="26456" checksum="60D4F20A060CAEB9" modified="2021-09-29" version="1">MALPILEVIRWKRLYYFSLFAFIISVVLFKFSPVISAIFMFSMLSWWTLLPGRISPYLMEINMGDFFTVMIALHIGPIEGAVFGFLNIWAGPIFGKAERMQLTSRISIVAIIATLLVPTIYNLTGQSVLYTLYGYSISFYTIHLASSLMISRRAFLNVMKFSLIAVPMAFITNKAYLSVFGEFSGWIVGSGIGIGSEMILATGAIMLFFSLMNFREFLIQKTGSRSPLLKSEKHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHG9</accession>
    <name>A0A832XHG9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium transport protein CorA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">corA</name>
        <name evidence="7" type="ORF">H1011_01255</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Mediates influx of magnesium ions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004488">
        <property type="entry name" value="Mg/Co-transport_prot_CorA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00383">
        <property type="entry name" value="corA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="312" mass="36834" checksum="124869AA940C226E" modified="2021-09-29" version="1">MEIYQFEKGHLKERTKIDLKNPTWIDLRDPTDEDISIVSKKLDIPGFVLRSYRESYRPRVEIYQDYTIVNVKSLATKKITPMKSLRKKQITFFISKKFVLTMHKGAKEIDNIKEKALAKENSKSFKNLNFLTYSILDEVIEGFGPVLESIDDHIDRLQDLIFEEAKQEHLEELFDLKRTMVKFHKVLWAQREAMFSLSRGAPGIDPDNVMYFRELYDSILYSVDREELLREMLTEILDSYLSVVSNNMNEVMKVLTVMATIMLPLTLITGIYGMNFRNMPEIYWEYGYYITLGIMATLGISMWMYFKRRGWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHH7</accession>
    <name>A0A832XHH7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Triosephosphate isomerase</fullName>
            <shortName evidence="2">TIM</shortName>
            <shortName evidence="2">TPI</shortName>
            <ecNumber evidence="2 3">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">tpiA</name>
        <name evidence="4" type="ORF">H1011_01415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="2 3"/>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_A">
        <property type="entry name" value="TIM_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022891">
        <property type="entry name" value="Triosephosphate_isomerase_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 3" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="13"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="204"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="2">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="225" mass="23085" checksum="E15FDA835AD0533A" modified="2021-09-29" version="1">MIGKREMALILLNLKAYEQGIGEKAETLASIAGELAKSSGVRIVISPQATDIAAVSKIVETFAQHVDSAPLGAQTGSILPESAKAAGATGSLLNHAERQISDDDIKTGVARLKALEMESMVCASTPELAAKYAEYGPTYIAIEPPELIGSGVSVSTANPDIVTESIEKVKAVNPSVKVVCGAGISSGEDLRKAIELGSEGALAASAFVKADDPKAVLEDLVGGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHJ8</accession>
    <name>A0A832XHJ8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">apt</name>
        <name evidence="12" type="ORF">H1011_01795</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="DVAD01000010">
        <property type="protein sequence ID" value="HIJ99540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="41"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="173" mass="19429" checksum="16453BAF91D0D270" modified="2021-09-29" version="1">MDLKDKIRDIQDFPKEGIVFRDITTLIQDPEAFQYVVDNFKNEFSGSEIDVIVGVESRGFIFGAALAYAMKIPFAIVRKPGKLPSTIVYEEYELEYGTDRLEVHDDAVKEGDKVLIVDDLLATGGTSRATANLIEKIGGEIAAFAFVIELSFLKGREKLKDYKLYSLVDYKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHK2</accession>
    <name>A0A832XHK2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rps12</name>
        <name evidence="5" type="ORF">H1011_01875</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 4">With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_A">
        <property type="entry name" value="Ribosomal_S12_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022863">
        <property type="entry name" value="Ribosomal_S12_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_S23_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="145" mass="16216" checksum="B9E5D35DD7E670B8" modified="2021-09-29" version="1">MARKPTGLYTARKLKKRRQRFRWSDRLYKRRALALNIRSSPLAGAPQAKGIVLEKVGLEAKQPNSAIRKCVRVQLTKNNKLVTAFMPGNNAISFINEHDEVDIVGIRGPMGKSKGDIPGVRFKVIKVNGISLPELIKGTKERSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHM7</accession>
    <name>A0A832XHM7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stage II sporulation protein M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002798">
        <property type="entry name" value="SpoIIM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01944">
        <property type="entry name" value="SpoIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="310" mass="34740" checksum="E09980BE76B2043E" modified="2021-09-29" version="1">MVLEMIMKPEYAQKSPIKTLLLGFGVSSVALWLSYLATLWLPTYIFPEHANSWFLFLTAVALIPFLNKIYLIEEREDERISEKNIFRRHEDLLFIYIFLFLGMILSFSFWFTILPLKISQIVFSGQVAEIYRIQGLKTSLSGALIATGAGAITGNIFAKITGYTISRVSFLKLVMFNNMRLLLLFMVFSFVFGAGAILLLTWNAAVVGVAMGFIIRDSILVSGSVLLKSAFYLKELPFSFMTFFLHGIFEIVGYFAAAISGGIFSVAILRGMHKTKHFKTILKDVVFFLVLALALVGIGAVLEVYVTPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XHR5</accession>
    <name>A0A832XHR5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_03075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="252" mass="28184" checksum="6CC314CEFE08D143" modified="2021-09-29" version="1">MRDILDKFCGKISKAKLAIRGVHTKEGNEADPEDYFDYRSGKVRYLKSNLTNALDSLQKEAWNLVELRDAHTGNEEIVLQILTTISELSKKTGDAQLLKILNRLEDLSSSLKLGAGSEKTPLFTDIPDIPEDVRADIVADLNEIRKSFEAGCNRAGVIMCGRVLETALLRKYYEATGIDLMETSPGIGLGKIIAKLTERDIRFDPGLTQQIHLINQVRISSVHTKKDSFYPSKGQTQAMILYTLDVIRKLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIH7</accession>
    <name>A0A832XIH7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UbiA family prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">H1011_00495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="286" mass="30903" checksum="793F59402581C77C" modified="2021-09-29" version="1">MGKRSALPKHIQTLDSVLKMTRPSAIVAYVILVFVAFLSTGGLPSAGLLSSTLIAVLSAAAGGFLLSDYYDLYIDKVNRPDRPLPAGKITPAAVWVFSLFFYALSIWAASSLPLISFLFVSGNLFLLFLYATTLKKVGFLGNITVAYLTASVFLLTTSVVGNIAAGAVPAALIFLYMGALEVLKDMEDVQGDFKFGARTLPLTEKDLGKYVAMAFMALTIALSPIPYYLGIFSVNYLILILIVDLSLVLLMHSLWRDSSLSSAIFYVRRIKASIVLSMAAFILGVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XII5</accession>
    <name>A0A832XII5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_00645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="371" mass="43887" checksum="3E598F0BE7D30FC3" modified="2021-09-29" version="1">MVDWRNYYSSGQEAYWASSPLINKSLVTLPRNYEIKIYKKIKKRIKKAKKKGLKTRIIVLGIGAGREFSDLYELHREFPDSLHQIIAVEPTDSLMNLAKKNLRKNGHYSPKFIKKVIFIEELLDRISENKKIKKLFEEPYMDIFTMFGFKFSEYNSTGQRKILENVYNLMDVRKAGEGRVNDELYMVGEPVEYFNKKRDDFVKSMYGMEPCLKSRERKHGRDVSFKKFSHEIKRYIDDKKTHPPYLMERFTFDKTYPCHMSKFGIWRTINEVEDELIDFIEEYEAYEDKNGIDRGEFSAITDNEVLVMPLEAFCNLHQGWTEERFEKKASEVGFRVKVTKGKARKGRSKKGKPSHKSYSQDALIALFWKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIJ0</accession>
    <name>A0A832XIJ0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Proteasome subunit alpha</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">20S proteasome alpha subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Proteasome core protein PsmA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">psmA</name>
        <name evidence="6" type="ORF">H1011_00720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 4">Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="2">The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3 4">Belongs to the peptidase T1A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019773">
        <property type="term" value="C:proteasome core complex, alpha-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00289_A">
        <property type="entry name" value="Proteasome_A_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023332">
        <property type="entry name" value="Proteasome_alpha-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019982">
        <property type="entry name" value="Proteasome_asu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000426">
        <property type="entry name" value="Proteasome_asu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10584">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00948">
        <property type="entry name" value="Proteasome_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03633">
        <property type="entry name" value="arc_protsome_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00388">
        <property type="entry name" value="PROTEASOME_ALPHA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51475">
        <property type="entry name" value="PROTEASOME_ALPHA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2 3" id="KW-0647">Proteasome</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PROTEASOME_ALPHA_1" evidence="5">
        <location>
            <begin position="9"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="244" mass="27310" checksum="389C724CCFCADFE1" modified="2021-09-29" version="1">MQPPQMMGYDRAITVFSPQGRLYQVEYAREAVKKGTISLGIVYSDGVLLAADKNVSEKLMVPGSIEKIYRVDKHIGAATSGLVADGRRIVDKARVMAQSHRITYEESMAVDSLTKEICDYQQLHTQVAGVRPFGTSMLIGGVDGDARLFETDPSGSYWEYMAAAIGENSDKVRDYFTKHYKQDMSRDQAIELALKGMRSADSSRFNEQNIELAYVEKGGKFDILSQDDCRTYMSKLSISKKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIL0</accession>
    <name>A0A832XIL0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PRC-barrel domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_01110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="2">
        <location>
            <begin position="7"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="111" mass="12199" checksum="A814949152846E31" modified="2021-09-29" version="1">MGETMTVTNLTNLTGKDVYTRGAEYVGKIEDAMLDTEKGSISGFTISMSRESFLYKTLSQGDQGVKKSVLIPYKEILACKDIVLVTAPKQIVPKQTEEEDHDESPIPGLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIL4</accession>
    <name>A0A832XIL4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">V-type ATP synthase subunit F</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">V-ATPase subunit F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">atpF</name>
        <name evidence="6" type="ORF">H1011_01185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the V-ATPase F subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00312">
        <property type="entry name" value="ATP_synth_F_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008218">
        <property type="entry name" value="ATPase_V1-cplx_f_g_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022944">
        <property type="entry name" value="ATPase_V1-cplx_fsu_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036906">
        <property type="entry name" value="ATPase_V1_fsu_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01990">
        <property type="entry name" value="ATP-synt_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159468">
        <property type="entry name" value="SSF159468"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="4 5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020758"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="105" mass="11809" checksum="E4A177BD175A45E8" modified="2021-09-29" version="1">MEIAIIGERDFTIGFQLCGIKNIANIEESDYSEFNSVFMQTIENTEVGIIVVNEGYYQKIPVQIRKKLEKLVSPVVVTLSDEESAGGADLRNLIKRSLGVDLWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIM3</accession>
    <name>A0A832XIM3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Small multi-drug export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009577">
        <property type="entry name" value="Sm_multidrug_ex"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36007">
        <property type="entry name" value="PTHR36007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06695">
        <property type="entry name" value="Sm_multidrug_ex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="153" mass="16992" checksum="320ADBF6DE1240BC" modified="2021-09-29" version="1">MVFLYIVLLSAAPFLELRGAIPFGIAAGLDYFTVFLVATTANIIIIPVIYMLFNTFFKELYKFPYIGTMFEKTVHKAHRKSKKYLDKYGYLGLAIFVSIPIPGSGAYTGSIVANFLEMDRRKAMLAIAAGVFVAGILVTLISIGFIESLRFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIN2</accession>
    <name>A0A832XIN2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF354 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_01495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007152">
        <property type="entry name" value="DUF354"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39662">
        <property type="entry name" value="PTHR39662"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04007">
        <property type="entry name" value="DUF354"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005357">
        <property type="entry name" value="UCP005357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="354" mass="39781" checksum="8F708C6C3D52CC2C" modified="2021-09-29" version="1">MKVWIDLLTPKQVMLYSKLIPMLEKSGEEVFVTTRDYKETSELLQTKRIEAVVVGKHGGASLEGKLSASIERMREMKGIVAKESPNIALSLSSPEAARVAFGLGIPHICINDIPEATAQSRLSVPLSEKIVAPKLIPKEVWAKYGMPPERVVQYDALDPVAWLRDFKPSDEVLNILELKNEKIITFRTSETNAAYLNESSNGEKVLIKPMIVEMSESFPDHRIVVLARYQEQADEIRNMRAKRVLVPDKVVDAQSLIYHSDLFIGGGGTMTLESALLGTPTLACRPMRTFYEDYVIEKQLVSRTTKEDLFEQASDLIKRNGEHKRRQRKIAGKMIRSMEDPAEVIANTVRSTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIP3</accession>
    <name>A0A832XIP3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_01720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000009">
        <property type="protein sequence ID" value="HIJ99526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043758">
        <property type="term" value="F:acetate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043938">
        <property type="entry name" value="Ligase_CoA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19045">
        <property type="entry name" value="Ligase_CoA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="1">
        <location>
            <begin position="10"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="460" mass="49097" checksum="0D8C173A8ED16F27" modified="2021-09-29" version="1">MSSKNGMKQLFNPESIAVIGASHNPSKVGSIILKNLKEGGFSGTLYPVNPDTAPILGLKTYSSIGRVKGQVDLAIISTPAKTVPKILEDCGLSGVKAVVIISSGFKEIGDKGEKLEDDLKKIIERHGITVVGPNCLGVYDSDSGIDTIFLPSYRMGRPKHGNISFISQSGAFGSALLDWSAEEGFGISKFISYGNAADVDEVDLLEYLGNDKDTKVISMYLEGASRPRELIEMGKKVTKKKPVVCLKVGRTEAGVKAAASHTGSLAGSDEIYSAAFKQAGILRADTIEEMFDYARAFSSQPQLKGNRIAIITDGGGFGVMAADSAEKHGLKMAELSKRTKNFLKKSLVPYASLGNPIDLTGVANDKHYAAAIDACMADSKVDCILVILLLQPPNVSSGSIETLIEINSQHRKPMLVCSAGGRYTKTHTDILEDSGIPVFPTPDRAAKAMAALYKYSKIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIQ2</accession>
    <name>A0A832XIQ2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="2">N5-CAIR mutase</shortName>
            <ecNumber evidence="2">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">purE</name>
        <name evidence="5" type="ORF">H1011_01980</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="2"/>
    <dbReference type="EMBL" id="DVAD01000012">
        <property type="protein sequence ID" value="HIJ99571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="1 2" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="4">
        <location>
            <begin position="2"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="141"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="HIJ99571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="189" mass="19942" checksum="8F4060CD2A6CF447" modified="2021-09-29" version="1">MKHITLLVGSETDMHIAESVKKVLDVYEVPYLCEVSSAHKNPDRVREIVRDSTSDVFICVASLSAALPGFVASITAKPVIGVPVDAKLGGLDSLLSTVQMPAGVPVAAVGVDNGKNAAYLALRMLGIKYPEALVKSGEGMPASTESPSSFAFFDLPGSSTTDTSSSDQTEDLESAEDEKPKERPSGDWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIR3</accession>
    <name>A0A832XIR3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000013">
        <property type="protein sequence ID" value="HIJ99616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="68"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="144" mass="15281" checksum="EA3FB7502E12F191" modified="2021-09-29" version="1">MAREETTTKKDEVLTIEGKGRDMLGRRNKGTLIIAGDVGDNVGYEQRKTGTITVNGNAGDDVGERNEGTITVNGNAGKGVGTINDGTITVNGNAGDNVGESNEGTIMVFGTIKSLSKGASDRKSKILAIDIEEDHGLPWRKYRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIW5</accession>
    <name>A0A832XIW5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TrmB family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="1">
        <location>
            <begin position="11"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="253" mass="27599" checksum="D6BCBBEEB03734DC" modified="2021-09-29" version="1">MSKNSDVLNLLNRVGLNKYESELYTALLKMGSSTAGELASKSDVPRSRVYDVLISLEKKGFALIQVGRPVKYTATAPERLLGSIVSNYEDDHKERLSEFERIKGSLLKGLSSIHGTEGSEDENMVGIIRGRSNIYSQMKTMISDSKSSIVKIASGESAGHFEKHCSSHIEGAKKRGVSSRLIINSGGKASDSKNINYSSDSRASKRSHGRFLVKDGEELLAFLKGGESALWIRDSSLAGSFAGLFETVWQNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIX3</accession>
    <name>A0A832XIX3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA-processing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019964">
        <property type="entry name" value="KH_domain_protein_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039912">
        <property type="entry name" value="PNO1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF13">
        <property type="entry name" value="PTHR12826:SF13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03665">
        <property type="entry name" value="arCOG04150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KH" evidence="1">
        <location>
            <begin position="3"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="KH" evidence="1">
        <location>
            <begin position="93"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="181" mass="19990" checksum="6C04372D76617881" modified="2021-09-29" version="1">MAEYIKIPKERLKLLTENKGKLIKYIESQSDTKISIDREAQEISIESSGKSEEIFDLWRARDTVKAVGRGAEPEAALDILESGAELQLVDLSEFVGKKHNALVRIKGRVIGTKGKAKNIIENLTNTQIFVYGKTVTIIGEHDMSIIARGAVELLAGGTMHSTAIRHIETELSKLGVKYKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XIY5</accession>
    <name>A0A832XIY5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsK</name>
        <name evidence="4" type="synonym">rps11</name>
        <name evidence="6" type="ORF">H1011_03595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Located on the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000016">
        <property type="protein sequence ID" value="HIJ99871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="74"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="HIJ99871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="130" mass="13923" checksum="FCD32DDD67AAA8E0" modified="2021-09-29" version="1">MANEGKKAIIRIYSSFNNTHITATDVTGAETISSMSGGMVVRLGKDKSKQYAAVQMASQVSEELVSKGFTSADVHVRAPGGNKSRSQGPGAKSAIRTLTRSSIKINKIEDSTPVQHGHLRKKGGRRGRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL51</accession>
    <name>A0A832XL51_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">V-type ATPase subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">H1011_01190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the V-ATPase V0D/AC39 subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1690.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036079">
        <property type="entry name" value="ATPase_su_c/d_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002843">
        <property type="entry name" value="ATPase_V0-cplx_csu/dsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044911">
        <property type="entry name" value="V-type_ATPase_su_c/d_dom_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035067">
        <property type="entry name" value="V-type_ATPase_suC/d"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01992">
        <property type="entry name" value="vATP-synt_AC39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103486">
        <property type="entry name" value="SSF103486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="HIJ99422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="344" mass="39827" checksum="8392D493EA86B4FB" modified="2021-09-29" version="1">MKITKKFAPTRGEISEEYYYAGTRARAGIAKRISDVDYDRFLKMGINEIVKFLEERDYKEAVDTLGMKYSKVELIERALYQNFAQVIDGILKYVPEQSPLITYITKYDIYNIKSILRGRSSGRSNEELERVMIPAGNLRHEFYLNLIENSSSVAEVVQGLKGTQYYKVLDGLDQNDIEELEDSLDKSYYEKSLAAGRGDSEFMDFVREEIDIKNAITILRLGNSKTKAESKYFIAGGKITVKSLKALAEKDLPSMIDFFKKRKFWKYVESGIKDIRKMETGLRKYLMMRSTVLLRDYNPNLKTVLGYIIVKEREMANVRMVVRSKQMKSAEMEVLVRSGMYLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL78</accession>
    <name>A0A832XL78_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="12">mRNA surveillance protein pelota</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">H1011_01805</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic release factor 1 family. Pelota subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000011">
        <property type="protein sequence ID" value="HIJ99542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070966">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, no-go decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070481">
        <property type="term" value="P:nuclear-transcribed mRNA catabolic process, non-stop decay"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071025">
        <property type="term" value="P:RNA surveillance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_1_Pelota"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038069">
        <property type="entry name" value="Pelota/DOM34_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004405">
        <property type="entry name" value="Transl-rel_pelota"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10853">
        <property type="entry name" value="PTHR10853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03463">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159065">
        <property type="entry name" value="SSF159065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00111">
        <property type="entry name" value="pelota"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1_1" evidence="9">
        <location>
            <begin position="4"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="eRF1_2" evidence="10">
        <location>
            <begin position="84"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="eRF1_3" evidence="11">
        <location>
            <begin position="205"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="HIJ99542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="304" mass="33648" checksum="D5E8917AA9BC1C55" modified="2021-09-29" version="1">ERHEKDTVLISVKAENIEFDKTVDRLRVTGNIVAGPETVPTGVTHTLNLKTGMVVTLQKIEWTPSELLRLDEASKAVRSKILLLAIEDGHGAIGMLRDYGVQELGEISESISGKQEEEAHESDTIKFFHLVAKAIENYPDIDRAVVAGPGFIRDDFGSFLKDKYPKLVDKVALEHISAGGNRGLQEIVKRGIIDRIVKETKIRIEMQFLEKFFVEISKDGGLAVRGIEEVMEASNMGAIDTLVVSNARLKKSKIEGITEVETLIKDIRDMKGEILIISGSHEPSEQFESLGGIGATLRFKIKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLA8</accession>
    <name>A0A832XLA8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_02385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="48" mass="5467" checksum="B2DA54C341C4A8F8" modified="2021-09-29" version="1">MAIETSLLLLVILIVIGFIVYRMVRGIWTVLLWVLIAGGVLFVVYYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="2" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLD2</accession>
    <name>A0A832XLD2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">H1011_02850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="131" mass="14827" checksum="6E2625D1EC9857FA" modified="2021-09-29" version="1">MGNRHGGRKWRKKELRDLPPKVIICSYCGELIKAGQGEWVGNEAYHKVPQQDDEKSCLDKAPLSQAPITPSRGARDRIKLEELRTKYLNKGLEELKKVAEGTPIPEVRLLLKKAGVPDSIIEELLNRSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLH3</accession>
    <name>A0A832XLH3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Aspartate carbamoyltransferase regulatory chain</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrI</name>
        <name evidence="10" type="ORF">H1011_03685</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in allosteric regulation of aspartate carbamoyltransferase.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Contains catalytic and regulatory chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PyrI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009347">
        <property type="term" value="C:aspartate carbamoyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00002">
        <property type="entry name" value="Asp_carb_tr_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020545">
        <property type="entry name" value="Asp_carbamoyltransf_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002801">
        <property type="entry name" value="Asp_carbamoylTrfase_reg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020542">
        <property type="entry name" value="Asp_carbamoyltrfase_reg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036792">
        <property type="entry name" value="Asp_carbatrfase_reg_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036793">
        <property type="entry name" value="Asp_carbatrfase_reg_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35805">
        <property type="entry name" value="PTHR35805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01948">
        <property type="entry name" value="PyrI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02748">
        <property type="entry name" value="PyrI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54893">
        <property type="entry name" value="SSF54893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57825">
        <property type="entry name" value="SSF57825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PyrI" evidence="8">
        <location>
            <begin position="8"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="PyrI_C" evidence="9">
        <location>
            <begin position="105"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="154" mass="16935" checksum="191C1D767E0FEC52" modified="2021-09-29" version="1">MIEKKEIKVSKIRNGTVLDHLNEGSAYRVLEMLGVDNDYGNPVIVLMGAESNSIERKDVIKIEDKFLEPDETGMLALISPNATISIIKNYNVVSKRKIGLPKKFIGVGQCPNPKCVSNQNEPISTVFNVETKDPLILSCGFCENVVDSSDISAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XLH6</accession>
    <name>A0A832XLH6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_03760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000018">
        <property type="protein sequence ID" value="HIJ99902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008965">
        <property type="entry name" value="CBM2/CBM3_carb-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49384">
        <property type="entry name" value="SSF49384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="220" mass="22691" checksum="3B7ECBAF38B84EA2" modified="2021-09-29" version="1">MRRTLAISTALFLILTVGVSAQLIIAVTLDAPSSADTSFDLEINTGEVSNLKTAEFTVSHGSEIEIASVSAGDYTSNAEIIFNEQTNSVLMTLPGSVSGSGTLAIINFNVLSQGSPEINLDGLLLGDDTGGEIFSTFGGAISIGVGGAAAVERVEQEVDTAALEEALLAELLGDGEDTADTAEEQSGSDEEPSAGIPTTYYIIGGVLLGLAYFLYSRSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UTZ0</accession>
    <name>A0A832UTZ0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">50S ribosomal protein L5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_02625</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="5">
        <location>
            <begin position="2"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="6">
        <location>
            <begin position="54"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="169" mass="19180" checksum="482000B9216E79ED" modified="2021-09-29" version="1">MIKISKVSVNIGVGSESDNLKKAELLLSRMFTAKPVRTIAKAAVPDFNIKKYSEIGVKLTLRGEDANTFLNQAFEAVENELKPTQIDTGGNLSFGVQEYMDLPHMKYDPDVGMFGMDVSVHLVKPGARIALRKIKRTRLPKKNRISYDESRNFFETNYTIKFVEPEEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UYS1</accession>
    <name>A0A832UYS1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">50S ribosomal protein L40e</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rpl40e</name>
        <name evidence="1" type="ORF">H1011_02985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000015">
        <property type="protein sequence ID" value="HIJ99763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038587">
        <property type="entry name" value="L40e_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="HIJ99763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="55" mass="6520" checksum="7C508A506A908948" modified="2021-09-29" version="1">MAKFPEAMKALFDNVYICMNCNATNRVDIKRFRLGKAKCRECKRKQLRPKKRGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZH2</accession>
    <name>A0A832UZH2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Inorganic phosphate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">H1011_01830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Potential transporter for phosphate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000011">
        <property type="protein sequence ID" value="HIJ99547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022324">
        <property type="entry name" value="Bacilysin_exporter_BacE_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01988">
        <property type="entry name" value="EXPORTERBACE"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="99"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="HIJ99547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="309" mass="32321" checksum="E8C2D15437882C7E" modified="2021-09-29" version="1">MELLAIIFALYLAWSVGVHTMGAMLGISIGSGIMRLREAVIISGLSVIVGAFFLSGRIIDTVGNELVSFGATGMTVVLVITAILLTVTAKKGLPIFTTYIVLGAAAGYAYTAGIAFNYGLFRNILIALFVSPLAGFAGGYLLYNIIKKTSLSKRKSIREREKFERKFAIPGIIALILMSLSIGGNSIGVVVGMLRGAMEVGPLSALGAIGVIIGLTTWSYKIAKTVGINITDLSPIRSFSAQISAGVVALTFIYLSIPISITQTLISATMGVGIARGRVGGEVSRNILFSWFVGLPLAILLAAGVGLIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832UZY5</accession>
    <name>A0A832UZY5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AI-2E family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_01820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000011">
        <property type="protein sequence ID" value="HIJ99545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="243"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="312" mass="32984" checksum="66F969004FA235AF" modified="2021-09-29" version="1">MKVLQVKLALIFALALIVLYPIIAPLVFAIVFGYLGRPLHKRLAEKIGAGTSAATVTALVLLIILFPVAAIVKSLVANAGSIAAFATKIIGKLSVIFEGTALSFDINSLSPAIQAGVEASGTLFISLPILVLNLFIMLLALFELLKNWDSISKYITQLAKKPKHLKIVKDINSLMIGIIDGYFGTAILFGALSYPLFLILGIELATFNAILVSVTTLIPMVGSWVMFAILGIYSYLVGNITTAVVLAIAGGIFGVAQIIVTPMLTKRRSPVHPALLLLGFIGGPMAFGVAGIILGPIIIGSLKIVLDSFKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V0L9</accession>
    <name>A0A832V0L9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglutaminase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">H1011_02360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000014">
        <property type="protein sequence ID" value="HIJ99642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="208"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="HIJ99642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="336" mass="38032" checksum="FEED65C5E4B99D9C" modified="2021-09-29" version="1">MRREKTLFSAKSIIPLVLVIVAGVFLFWNFYTPEVYRNDLVLSMTANISYSNTIPIIEAGDSPLPANMSVITYNIPSDFEAQVVLLSGISEPYSFHTDKFGNKYKKLIFQNPELGINYYELWAIVEVLPISFEIPPTSVGNVNEVLSEYKESSEMVQSDSSSIILLAEEITQEAETQFEEAVAINHWVYTNINYDSAYINVTNDALWTYENRVGVCTEYAHLTSALMRARGIPARIAYGAAPYDYPDGWLPHTWVEAYFNGTWYPFDPTWDLSGRLDATHIKIASLPDQSYVFINVTLSGKNIDLGSLSQSKLQVEIIDSKEESPKLDWEILRKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832V1E8</accession>
    <name>A0A832V1E8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000003">
        <property type="protein sequence ID" value="HIJ99261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="180" mass="20223" checksum="C4CE2613FD43B01D" modified="2021-09-29" version="1">MKTGAKVLLTTIIVCMVLPMLLYPETWKGVILVSLITIASRSSSIYDNLKLEFHSVFLIAAVATLGLSEAMYAIIMSTIFLNPAGKILGNIQKIPWVIMDMISLFCVVIVVSFAPPHLLYQFSLWSIILITNVLFSIIRNRVFFDPLDRRIAFGFFNTIGNYFLLTYYFNGILGIVANTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-05-25" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XFR4</accession>
    <name>A0A832XFR4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">V-ATPase subunit E</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">H1011_01195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the V-ATPase E subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000007">
        <property type="protein sequence ID" value="HIJ99423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033178">
        <property type="term" value="C:proton-transporting two-sector ATPase complex, catalytic domain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2320.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038495">
        <property type="entry name" value="ATPase_E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002842">
        <property type="entry name" value="ATPase_V1_Esu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01991">
        <property type="entry name" value="vATP-synt_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="26"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="HIJ99423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="187" mass="21004" checksum="21E8E9006D0D5A1D" modified="2021-09-29" version="1">MGLKEVEKEIHQRLESKSKAIENLGGKEANSIIAEARDKIKSLTSERNKSIENIIRGLDKKESAFENLQARKIDLSMRKDIMETAYSRAFAEAAKMPTTKRKIFLTELLKKGKKEIEAVGVYTNENDKGIMKTLAPKLKHLGIIETTGGIILVTKDGNVQVDYTFETIFEETRKTSLKGVSDILFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL29</accession>
    <name>A0A832XL29_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="10">50S ribosomal protein L7ae</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">H1011_00800</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000004">
        <property type="protein sequence ID" value="HIJ99347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_L7Ae/L30e/S12e/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_L7Ae/L8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000948">
        <property type="entry name" value="Ribosomal_L7Ae_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00884">
        <property type="entry name" value="RIBOSOMALHS6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Ribosomal_L7Ae" evidence="9">
        <location>
            <begin position="10"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="109"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="114"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="10">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="HIJ99347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="144" mass="15403" checksum="78C6DD8A80A5BB10" modified="2021-09-29" version="1" fragment="single">MTENQELVNKAYSLLNIVSETGKLRKGTNESTKAIERKQTKLVIFAEDVSPPEVVAHITPLCKEREIPCIGVPLRSELGKAAGLSVPTACVAIVDAGEGKNQLTDLVSEISKAGSRKPAEKKAPAEEKPAEAPKEEAPAEKSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A832XL33</accession>
    <name>A0A832XL33_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">H1011_00875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Candidatus Undinarchaeum marinum</name>
        <dbReference type="NCBI Taxonomy" id="2756141"/>
        <lineage>
            <taxon>Archaea</taxon>
            <taxon>Candidatus Undinarchaeota</taxon>
            <taxon>Candidatus Undinarchaeia</taxon>
            <taxon>Candidatus Undinarchaeales</taxon>
            <taxon>Candidatus Undinarchaeaceae</taxon>
            <taxon>Candidatus Undinarchaeum</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="journal article" name="Nat. Commun." volume="11" first="0" last="0">
            <title>Undinarchaeota illuminate DPANN phylogeny and the impact of gene transfer on archaeal evolution.</title>
            <authorList>
                <person name="Dombrowski N."/>
                <person name="Williams T.A."/>
                <person name="Sun J."/>
                <person name="Woodcroft B.J."/>
                <person name="Lee J.H."/>
                <person name="Minh B.Q."/>
                <person name="Rinke C."/>
                <person name="Spang A."/>
            </authorList>
            <dbReference type="PubMed" id="32770105"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">MAG_bin17</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="DVAD01000006">
        <property type="protein sequence ID" value="HIJ99362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000604391">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="HIJ99362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000604391"/>
        </source>
    </evidence>
    <sequence length="266" mass="29981" checksum="7798580DF28C07AF" modified="2021-09-29" version="1">MSRKAQSNALLWMAEMVIFSGLFVMVGITSVDLIKQTQIESTDLVATEILETLIASEECLRVPGSIAKGVIELLGAEQKGDCIQKYPYVWKAEIKDFHSSTTTHILPPVNLHYSHSNHCDFPTYASIPVTIDKGSSGHKKGVLKVEVGSLAFRANPRIQGGELFLTFDSFADCDMNLNITENWYEKGSTEPDYIYVYNETGALSPSIFKLNETWYGEKTRDFAPNVYKHGREITDFSKYDRYSLEISVVDADSDIIYTSRVERFLD</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>