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<entry dataset="TrEMBL" created="2005-07-05" modified="2022-08-03" version="37" xmlns="http://uniprot.org/uniprot">
    <accession>Q4VMI2</accession>
    <name>Q4VMI2_9TOMB</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA silencing suppressor p19</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">19 kDa symptom severity modulator</fullName>
        </alternativeName>
    </protein>
    <organism evidence="4 5">
        <name type="scientific">Grapevine Algerian latent virus</name>
        <dbReference type="NCBI Taxonomy" id="208084"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Kitrinoviricota</taxon>
            <taxon>Tolucaviricetes</taxon>
            <taxon>Tolivirales</taxon>
            <taxon>Tombusviridae</taxon>
            <taxon>Procedovirinae</taxon>
            <taxon>Tombusvirus</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="journal article" date="2006" name="J. Gen. Plant Pathol." volume="72" first="119" last="122">
            <title>Characterization of Grapevine Algerian latent virus isolated from nipplefruit (Solanum mammosum) in Japan.</title>
            <authorList>
                <person name="Ohki T."/>
                <person name="Uematsu K."/>
                <person name="Nakayama Y."/>
                <person name="Lesemann D.-E."/>
                <person name="Honda Y."/>
                <person name="Tsuda S."/>
                <person name="Fujisawa I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5">nipplefruit</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <dbReference type="EMBL" id="AY830918">
        <property type="protein sequence ID" value="AAX76895.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308433.1">
        <property type="nucleotide sequence ID" value="NC_011535.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q4VMI2"/>
    <dbReference type="GeneID" id="7042879"/>
    <dbReference type="KEGG" id="vg:7042879"/>
    <dbReference type="Proteomes" id="UP000202829">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044423">
        <property type="term" value="C:virion component"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004905">
        <property type="entry name" value="Tombusvirus_p19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036131">
        <property type="entry name" value="VP19_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03220">
        <property type="entry name" value="Tombus_P19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103145">
        <property type="entry name" value="SSF103145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="AAX76895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000202829"/>
        </source>
    </evidence>
    <sequence length="172" mass="19457" checksum="7949D96A827D0C88" modified="2005-07-05" version="1">MERTIQGSDVREQANSERWDGGCGSTITPFKLPDESPSLYEWRLHNSEESEDKDHPLGFKESWCFGKVVFKRYLRYDGTEASLHRALGSWERSSVNDAASRFLGLGQIGCTYSIRFRGSCLTLSGGSRTLQRLIEMAIRTKCTMLQLAPCEVESDVSRRCPEGTEAFEKESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2005-07-05" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>Q4VMI3</accession>
    <name>Q4VMI3_9TOMB</name>
    <protein>
        <submittedName>
            <fullName evidence="8">24K protein</fullName>
        </submittedName>
    </protein>
    <organism evidence="8 9">
        <name type="scientific">Grapevine Algerian latent virus</name>
        <dbReference type="NCBI Taxonomy" id="208084"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Kitrinoviricota</taxon>
            <taxon>Tolucaviricetes</taxon>
            <taxon>Tolivirales</taxon>
            <taxon>Tombusviridae</taxon>
            <taxon>Procedovirinae</taxon>
            <taxon>Tombusvirus</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="journal article" date="2006" name="J. Gen. Plant Pathol." volume="72" first="119" last="122">
            <title>Characterization of Grapevine Algerian latent virus isolated from nipplefruit (Solanum mammosum) in Japan.</title>
            <authorList>
                <person name="Ohki T."/>
                <person name="Uematsu K."/>
                <person name="Nakayama Y."/>
                <person name="Lesemann D.-E."/>
                <person name="Honda Y."/>
                <person name="Tsuda S."/>
                <person name="Fujisawa I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9">nipplefruit</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Host membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the tombusvirus/aureusvirus movement protein p22 family.</text>
    </comment>
    <dbReference type="EMBL" id="AY830918">
        <property type="protein sequence ID" value="AAX76896.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308432.1">
        <property type="nucleotide sequence ID" value="NC_011535.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7042878"/>
    <dbReference type="KEGG" id="vg:7042878"/>
    <dbReference type="Proteomes" id="UP000202829">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033644">
        <property type="term" value="C:host cell membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019028">
        <property type="term" value="C:viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046740">
        <property type="term" value="P:transport of virus in host, cell to cell"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005332">
        <property type="entry name" value="TBSV_p22"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03558">
        <property type="entry name" value="TBSV_P22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1043">Host membrane</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <keyword evidence="6" id="KW-0916">Viral movement protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="AAX76896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000202829"/>
        </source>
    </evidence>
    <sequence length="210" mass="23787" checksum="526E3F3AC1A6C83B" modified="2005-07-05" version="1">MIWAHLSACQARKGLLEQDQFMDTEYEQVNKPWNELYKEATLGNKLTVNVGMEDAEVPLLPSNFLTKVRVSMSGGYITVRRVRIKIIPLVSRKAGVSGKLYLRDISDTTGRKLHCTELLDLGREVRLTMQHLDFLVSARSDVPIVFGFEDLVSPYLEGRELFSVSLKWQFGLSAQCYSLPPAKWKVMYQEDALKALKPSKKKASKTDSSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2005-07-05" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>Q4VMI4</accession>
    <name>Q4VMI4_9TOMB</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Capsid protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Coat protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">p41</fullName>
        </alternativeName>
    </protein>
    <organism evidence="9 10">
        <name type="scientific">Grapevine Algerian latent virus</name>
        <dbReference type="NCBI Taxonomy" id="208084"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Kitrinoviricota</taxon>
            <taxon>Tolucaviricetes</taxon>
            <taxon>Tolivirales</taxon>
            <taxon>Tombusviridae</taxon>
            <taxon>Procedovirinae</taxon>
            <taxon>Tombusvirus</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="journal article" date="2006" name="J. Gen. Plant Pathol." volume="72" first="119" last="122">
            <title>Characterization of Grapevine Algerian latent virus isolated from nipplefruit (Solanum mammosum) in Japan.</title>
            <authorList>
                <person name="Ohki T."/>
                <person name="Uematsu K."/>
                <person name="Nakayama Y."/>
                <person name="Lesemann D.-E."/>
                <person name="Honda Y."/>
                <person name="Tsuda S."/>
                <person name="Fujisawa I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10">nipplefruit</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homomultimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the icosahedral plant coat protein family.</text>
    </comment>
    <dbReference type="EMBL" id="AY830918">
        <property type="protein sequence ID" value="AAX76897.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308431.1">
        <property type="nucleotide sequence ID" value="NC_011535.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7042877"/>
    <dbReference type="KEGG" id="vg:7042877"/>
    <dbReference type="Proteomes" id="UP000202829">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039617">
        <property type="term" value="C:T=3 icosahedral viral capsid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000937">
        <property type="entry name" value="Capsid_prot_S-dom_vir"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029053">
        <property type="entry name" value="Viral_coat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00729">
        <property type="entry name" value="Viral_coat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00233">
        <property type="entry name" value="ICOSAHEDRAL"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0167">Capsid protein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-1142">T=3 icosahedral capsid protein</keyword>
    <keyword evidence="5" id="KW-0946">Virion</keyword>
    <feature type="domain" description="Viral_coat" evidence="8">
        <location>
            <begin position="67"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="AAX76897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000202829"/>
        </source>
    </evidence>
    <sequence length="376" mass="39735" checksum="792650E3C06F5DC0" modified="2005-07-05" version="1">MALALNTRRNNNGKVMEMLAYKAATAGAELALANVGGITRGVAQLGKSMMGKKKRNKNVSQVGALGGAVVAPVAVTRQIRGSKPRFSGRGTGSITVTHREYLGQVVTTADLQVNGGITGNLLKVNPLNGILFSWLPTIAAGYDQYAFNRLSLQYVPLCATTATGRVAMYWDKDSTDLEPTDRVELANQAILKETSPWAEANLTIPTDRIKRFCDDSAVADRKLVDLGQLGVATYGGTAVVAGDVFVSYTVTFYNPQPLATLMDTTRINASNTVITNVGPQYSRIDVVSGNQWLITFRGVGKFVIFGSIRGTGAVVLALSGVIVNSSTTLTTPTGAMYVANVTVSSLPASLSYTMTTVTAGLHSAVRATRANDMGTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2005-07-05" modified="2022-08-03" version="43" xmlns="http://uniprot.org/uniprot">
    <accession>Q4VMI5</accession>
    <name>Q4VMI5_9TOMB</name>
    <protein>
        <submittedName>
            <fullName evidence="3">33K protein</fullName>
        </submittedName>
    </protein>
    <organism evidence="3 4">
        <name type="scientific">Grapevine Algerian latent virus</name>
        <dbReference type="NCBI Taxonomy" id="208084"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Kitrinoviricota</taxon>
            <taxon>Tolucaviricetes</taxon>
            <taxon>Tolivirales</taxon>
            <taxon>Tombusviridae</taxon>
            <taxon>Procedovirinae</taxon>
            <taxon>Tombusvirus</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="journal article" date="2006" name="J. Gen. Plant Pathol." volume="72" first="119" last="122">
            <title>Characterization of Grapevine Algerian latent virus isolated from nipplefruit (Solanum mammosum) in Japan.</title>
            <authorList>
                <person name="Ohki T."/>
                <person name="Uematsu K."/>
                <person name="Nakayama Y."/>
                <person name="Lesemann D.-E."/>
                <person name="Honda Y."/>
                <person name="Tsuda S."/>
                <person name="Fujisawa I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4">nipplefruit</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AY830918">
        <property type="protein sequence ID" value="AAX76899.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308430.1">
        <property type="nucleotide sequence ID" value="NC_011535.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7042880"/>
    <dbReference type="KEGG" id="vg:7042880"/>
    <dbReference type="Proteomes" id="UP000202829">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013707">
        <property type="entry name" value="Tombusvirus_p33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08500">
        <property type="entry name" value="Tombus_P33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Tombus_P33" evidence="2">
        <location>
            <begin position="142"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="AAX76899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000202829"/>
        </source>
    </evidence>
    <sequence length="296" mass="33322" checksum="1EA1954E80D40074" modified="2005-07-05" version="1">METIRRMIWPKKEIFVGDFAIGVNRTAPVDIFQLVCRVVLRYMRTGKIECDSDSMTKFLVELLKTDCAAKWEWFMKRRQRGDYIVPLSIAALPVIPLLSYATKVRAVSVKAFGNELSFNIRVPRPSVPKKGLLLRLAAGLALAPICALAVYATLPREKLSVFKLRTEARAHMEDEREATDCLVVEPARELKGKDGEDLLTGSRMTKVIASTGRPRRRPYAAKIAQVARAKVGYLKNSPENRLIYQRVMIEIMDKDCVRYVDRDVILPLAIGCCFVYPDGVEESAALWGSQESLGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2005-07-05" modified="2022-08-03" version="63" xmlns="http://uniprot.org/uniprot">
    <accession>Q4VMI6</accession>
    <name>Q4VMI6_9TOMB</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">RNA-directed RNA polymerase</fullName>
            <ecNumber evidence="3 10">2.7.7.48</ecNumber>
        </recommendedName>
    </protein>
    <organism evidence="13 14">
        <name type="scientific">Grapevine Algerian latent virus</name>
        <dbReference type="NCBI Taxonomy" id="208084"/>
        <lineage>
            <taxon>Viruses</taxon>
            <taxon>Riboviria</taxon>
            <taxon>Orthornavirae</taxon>
            <taxon>Kitrinoviricota</taxon>
            <taxon>Tolucaviricetes</taxon>
            <taxon>Tolivirales</taxon>
            <taxon>Tombusviridae</taxon>
            <taxon>Procedovirinae</taxon>
            <taxon>Tombusvirus</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="journal article" date="2006" name="J. Gen. Plant Pathol." volume="72" first="119" last="122">
            <title>Characterization of Grapevine Algerian latent virus isolated from nipplefruit (Solanum mammosum) in Japan.</title>
            <authorList>
                <person name="Ohki T."/>
                <person name="Uematsu K."/>
                <person name="Nakayama Y."/>
                <person name="Lesemann D.-E."/>
                <person name="Honda Y."/>
                <person name="Tsuda S."/>
                <person name="Fujisawa I."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">nipplefruit</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">RNA-dependent RNA polymerase that plays an essential role in the virus replication.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.48"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the tombusviridae RNA polymerase family.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.48" evidence="3 10"/>
    <dbReference type="EMBL" id="AY830918">
        <property type="protein sequence ID" value="AAX76898.1"/>
        <property type="molecule type" value="Genomic_RNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="YP_002308429.1">
        <property type="nucleotide sequence ID" value="NC_011535.1"/>
    </dbReference>
    <dbReference type="GeneID" id="7042881"/>
    <dbReference type="KEGG" id="vg:7042881"/>
    <dbReference type="Proteomes" id="UP000202829">
        <property type="component" value="Genome"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003968">
        <property type="term" value="F:RNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0039694">
        <property type="term" value="P:viral RNA genome replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007094">
        <property type="entry name" value="RNA-dir_pol_PSvirus"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002166">
        <property type="entry name" value="RNA_pol_HCV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013707">
        <property type="entry name" value="Tombusvirus_p33"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00998">
        <property type="entry name" value="RdRP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08500">
        <property type="entry name" value="Tombus_P33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50507">
        <property type="entry name" value="RDRP_SSRNA_POS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0696">RNA-directed RNA polymerase</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="9 10" id="KW-0693">Viral RNA replication</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="RdRp catalytic" evidence="12">
        <location>
            <begin position="524"/>
            <end position="641"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="AAX76898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000202829"/>
        </source>
    </evidence>
    <sequence length="818" mass="92185" checksum="D5A7AB645D0FABEA" modified="2005-07-05" version="1"> </sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>