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    <accession>H9L4C7</accession>
    <name>H9L4C7_STRCO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Major plasmid transfer protein, TraA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">traA</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)</name>
        <dbReference type="NCBI Taxonomy" id="100226"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Streptomycetales</taxon>
            <taxon>Streptomycetaceae</taxon>
            <taxon>Streptomyces</taxon>
            <taxon>Streptomyces albidoflavus group</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2 3">
        <name>SCP2</name>
    </geneLocation>
    <reference evidence="2 3" key="1">
        <citation type="journal article" date="2002" name="Nature" volume="417" first="141" last="147">
            <title>Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).</title>
            <authorList>
                <person name="Bentley S.D."/>
                <person name="Chater K.F."/>
                <person name="Cerdeno-Tarraga A.M."/>
                <person name="Challis G.L."/>
                <person name="Thomson N.R."/>
                <person name="James K.D."/>
                <person name="Harris D.E."/>
                <person name="Quail M.A."/>
                <person name="Kieser H."/>
                <person name="Harper D."/>
                <person name="Bateman A."/>
                <person name="Brown S."/>
                <person name="Chandra G."/>
                <person name="Chen C.W."/>
                <person name="Collins M."/>
                <person name="Cronin A."/>
                <person name="Fraser A."/>
                <person name="Goble A."/>
                <person name="Hidalgo J."/>
                <person name="Hornsby T."/>
                <person name="Howarth S."/>
                <person name="Huang C.H."/>
                <person name="Kieser T."/>
                <person name="Larke L."/>
                <person name="Murphy L."/>
                <person name="Oliver K."/>
                <person name="O'Neil S."/>
                <person name="Rabbinowitsch E."/>
                <person name="Rajandream M.A."/>
                <person name="Rutherford K."/>
                <person name="Rutter S."/>
                <person name="Seeger K."/>
                <person name="Saunders D."/>
                <person name="Sharp S."/>
                <person name="Squares R."/>
                <person name="Squares S."/>
                <person name="Taylor K."/>
                <person name="Warren T."/>
                <person name="Wietzorrek A."/>
                <person name="Woodward J."/>
                <person name="Barrell B.G."/>
                <person name="Parkhill J."/>
                <person name="Hopwood D.A."/>
            </authorList>
            <dbReference type="PubMed" id="12000953"/>
            <dbReference type="DOI" id="10.1038/417141a"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3">ATCC BAA-471 / A3(2) / M145</strain>
            <plasmid evidence="2">SCP2</plasmid>
        </source>
    </reference>
    <dbReference type="EMBL" id="AL645771">
        <property type="protein sequence ID" value="CAD12013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="PIR" id="S58315">
        <property type="entry name" value="S58315"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_639782.1">
        <property type="nucleotide sequence ID" value="NC_003904.1"/>
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    <dbReference type="RefSeq" id="WP_011039594.1">
        <property type="nucleotide sequence ID" value="NC_003904.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1095077"/>
    <dbReference type="KEGG" id="sco:SCP2.20c"/>
    <dbReference type="PATRIC" id="fig|100226.15.peg.8315"/>
    <dbReference type="HOGENOM" id="CLU_570971_0_0_11"/>
    <dbReference type="OMA" id="WNIMKER"/>
    <dbReference type="Proteomes" id="UP000001973">
        <property type="component" value="Plasmid SCP2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0614">Plasmid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="CAD12013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000001973"/>
        </source>
    </evidence>
    <sequence length="478" mass="50421" checksum="40C54F2BE2FFF1C7" modified="2012-05-16" version="1">MRVEAPDTQLLALPRLPLARALGVEDPELLMIETDGMAHGVVTLYREHPLLTVREATPDDLVMDRHGRIAIGMRHDGRPARWPLYDPELGALTDLLVGAPGSGKSVTLLTLIAAERTNGIVSVVADAQDGMSLPEAEGRVFHFGAGQAEAAATLAAYSAVASYRQEVSAANGWGSFTLGKPWRLAILTMDEINRMLAMDSGLPAPFRMWVAGMLGAGQITWRKVGMGVRIAGQSIHLADLADSEKIRANAKNGSVWLGRVNSSMTRSMASDMTTGAVEITPVPKYFGVTGTAELDAAWSGDEAPTGPVTAGTAWLIQSGQPYLSRVWRAVKEARTYPSLIGLMESSPLVDFTPPEADVFRRAYDEALTIAVALLEGDEDGGGAPAPAAPRRTEQAADAGSSRVPTPPATARTLQVLVLDALAAGQLRTREIRKAVGAGTDGGPSSGSVDNALQALQDAGLVARVTHGVWARTDQADPS</sequence>
</entry>
<entry dataset="Swiss-Prot" created="2013-10-16" modified="2022-05-25" version="59" xmlns="http://uniprot.org/uniprot">
    <accession>Q7AKG9-2</accession>
    <name>SIGR_STRCO</name>
    <protein>
        <recommendedName>
            <fullName>Isoform SigR prime of ECF RNA polymerase sigma factor SigR</fullName>
            <shortName>ECF sigma factor SigR</shortName>
        </recommendedName>
        <alternativeName>
            <fullName>Alternative RNA polymerase sigma factor SigR</fullName>
        </alternativeName>
        <alternativeName>
            <fullName>RNA polymerase sigma-R factor</fullName>
            <shortName>Sigma-R factor</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name type="primary">sigR</name>
        <name type="ordered locus">SCO5216</name>
    </gene>
    <organism>
        <name type="scientific">Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)</name>
        <dbReference type="NCBI Taxonomy" id="100226"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Streptomycetales</taxon>
            <taxon>Streptomycetaceae</taxon>
            <taxon>Streptomyces</taxon>
            <taxon>Streptomyces albidoflavus group</taxon>
        </lineage>
    </organism>
    <reference key="1">
        <citation type="journal article" date="1998" name="EMBO J." volume="17" first="5776" last="5782">
            <title>sigmaR, an RNA polymerase sigma factor that modulates expression of the thioredoxin system in response to oxidative stress in Streptomyces coelicolor A3(2).</title>
            <authorList>
                <person name="Paget M.S."/>
                <person name="Kang J.G."/>
                <person name="Roe J.H."/>
                <person name="Buttner M.J."/>
            </authorList>
            <dbReference type="PubMed" id="9755177"/>
            <dbReference type="DOI" id="10.1093/emboj/17.19.5776"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [GENOMIC DNA]</scope>
        <scope>PROTEIN SEQUENCE OF 5-24</scope>
        <scope>FUNCTION AS A SIGMA FACTOR</scope>
        <scope>INDUCTION</scope>
        <scope>AUTOREGULATION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <source>
            <strain>ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <reference key="2">
        <citation type="journal article" date="1999" name="EMBO J." volume="18" first="4292" last="4298">
            <title>RsrA, an anti-sigma factor regulated by redox change.</title>
            <authorList>
                <person name="Kang J.G."/>
                <person name="Paget M.S.B."/>
                <person name="Seok Y.J."/>
                <person name="Hahn M.Y."/>
                <person name="Bae J.B."/>
                <person name="Hahn J.S."/>
            </authorList>
            <dbReference type="PubMed" id="10428967"/>
            <dbReference type="DOI" id="10.1093/emboj/18.15.4292"/>
        </citation>
        <scope>FUNCTION AS A SIGMA-FACTOR</scope>
        <scope>INTERACTION WITH RSRA</scope>
        <scope>SUBUNIT</scope>
        <source>
            <strain>ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <reference key="3">
        <citation type="journal article" date="2001" name="Mol. Microbiol." volume="42" first="1007" last="1020">
            <title>Defining the disulphide stress response in Streptomyces coelicolor A3(2): identification of the sigmaR regulon.</title>
            <authorList>
                <person name="Paget M.S.B."/>
                <person name="Molle V."/>
                <person name="Cohen G."/>
                <person name="Aharonowitz Y."/>
                <person name="Buttner M.J."/>
            </authorList>
            <dbReference type="PubMed" id="11737643"/>
            <dbReference type="DOI" id="10.1046/j.1365-2958.2001.02675.x"/>
        </citation>
        <scope>FUNCTION</scope>
        <scope>SUBUNIT</scope>
        <scope>REGULON</scope>
        <source>
            <strain>ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <reference key="4">
        <citation type="journal article" date="2002" name="J. Mol. Biol." volume="323" first="225" last="236">
            <title>Identification and structure of the anti-sigma factor-binding domain of the disulphide-stress regulated sigma factor sigma(R) from Streptomyces coelicolor.</title>
            <authorList>
                <person name="Li W."/>
                <person name="Stevenson C.E."/>
                <person name="Burton N."/>
                <person name="Jakimowicz P."/>
                <person name="Paget M.S."/>
                <person name="Buttner M.J."/>
                <person name="Lawson D.M."/>
                <person name="Kleanthous C."/>
            </authorList>
            <dbReference type="PubMed" id="12381317"/>
            <dbReference type="DOI" id="10.1016/S0022-2836(02)00948-8"/>
        </citation>
        <scope>X-RAY CRYSTALLOGRAPHY (2.38 ANGSTROMS) OF 23-109</scope>
        <scope>INTERACTION WITH RSRA</scope>
        <source>
            <strain>ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <reference key="5">
        <citation type="journal article" date="2002" name="Nature" volume="417" first="141" last="147">
            <title>Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).</title>
            <authorList>
                <person name="Bentley S.D."/>
                <person name="Chater K.F."/>
                <person name="Cerdeno-Tarraga A.M."/>
                <person name="Challis G.L."/>
                <person name="Thomson N.R."/>
                <person name="James K.D."/>
                <person name="Harris D.E."/>
                <person name="Quail M.A."/>
                <person name="Kieser H."/>
                <person name="Harper D."/>
                <person name="Bateman A."/>
                <person name="Brown S."/>
                <person name="Chandra G."/>
                <person name="Chen C.W."/>
                <person name="Collins M."/>
                <person name="Cronin A."/>
                <person name="Fraser A."/>
                <person name="Goble A."/>
                <person name="Hidalgo J."/>
                <person name="Hornsby T."/>
                <person name="Howarth S."/>
                <person name="Huang C.H."/>
                <person name="Kieser T."/>
                <person name="Larke L."/>
                <person name="Murphy L."/>
                <person name="Oliver K."/>
                <person name="O'Neil S."/>
                <person name="Rabbinowitsch E."/>
                <person name="Rajandream M.A."/>
                <person name="Rutherford K."/>
                <person name="Rutter S."/>
                <person name="Seeger K."/>
                <person name="Saunders D."/>
                <person name="Sharp S."/>
                <person name="Squares R."/>
                <person name="Squares S."/>
                <person name="Taylor K."/>
                <person name="Warren T."/>
                <person name="Wietzorrek A."/>
                <person name="Woodward J."/>
                <person name="Barrell B.G."/>
                <person name="Parkhill J."/>
                <person name="Hopwood D.A."/>
            </authorList>
            <dbReference type="PubMed" id="12000953"/>
            <dbReference type="DOI" id="10.1038/417141a"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain>ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <reference key="6">
        <citation type="journal article" date="2003" name="J. Mol. Biol." volume="333" first="461" last="472">
            <title>The role of zinc in the disulphide stress-regulated anti-sigma factor RsrA from Streptomyces coelicolor.</title>
            <authorList>
                <person name="Li W."/>
                <person name="Bottrill A.R."/>
                <person name="Bibb M.J."/>
                <person name="Buttner M.J."/>
                <person name="Paget M.S."/>
                <person name="Kleanthous C."/>
            </authorList>
            <dbReference type="PubMed" id="14529630"/>
            <dbReference type="DOI" id="10.1016/j.jmb.2003.08.038"/>
        </citation>
        <scope>FUNCTION AS A SIGMA FACTOR</scope>
        <scope>INTERACTION WITH RSRA</scope>
        <source>
            <strain>ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <reference key="7">
        <citation type="journal article" date="2008" name="Mol. Microbiol." volume="68" first="861" last="870">
            <title>Mycothiol regulates and is regulated by a thiol-specific antisigma factor RsrA and sigma(R) in Streptomyces coelicolor.</title>
            <authorList>
                <person name="Park J.H."/>
                <person name="Roe J.H."/>
            </authorList>
            <dbReference type="PubMed" id="18430082"/>
            <dbReference type="DOI" id="10.1111/j.1365-2958.2008.06191.x"/>
        </citation>
        <scope>REGULON</scope>
        <scope>INDUCTION</scope>
        <scope>DISRUPTION PHENOTYPE</scope>
        <source>
            <strain>ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <reference key="8">
        <citation type="journal article" date="2009" name="Mol. Microbiol." volume="73" first="815" last="825">
            <title>Positive and negative feedback regulatory loops of thiol-oxidative stress response mediated by an unstable isoform of sigmaR in actinomycetes.</title>
            <authorList>
                <person name="Kim M.S."/>
                <person name="Hahn M.Y."/>
                <person name="Cho Y."/>
                <person name="Cho S.N."/>
                <person name="Roe J.H."/>
            </authorList>
            <dbReference type="PubMed" id="19682253"/>
            <dbReference type="DOI" id="10.1111/j.1365-2958.2009.06824.x"/>
        </citation>
        <scope>INDUCTION</scope>
        <scope>ALTERNATIVE INITIATION (SIGR PRIME)</scope>
        <scope>PROBABLE CLEAVAGE</scope>
        <source>
            <strain>ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <reference key="9">
        <citation type="journal article" date="2012" name="Mol. Microbiol." volume="85" first="326" last="344">
            <title>Conservation of thiol-oxidative stress responses regulated by SigR orthologues in actinomycetes.</title>
            <authorList>
                <person name="Kim M.S."/>
                <person name="Dufour Y.S."/>
                <person name="Yoo J.S."/>
                <person name="Cho Y.B."/>
                <person name="Park J.H."/>
                <person name="Nam G.B."/>
                <person name="Kim H.M."/>
                <person name="Lee K.L."/>
                <person name="Donohue T.J."/>
                <person name="Roe J.H."/>
            </authorList>
            <dbReference type="PubMed" id="22651816"/>
            <dbReference type="DOI" id="10.1111/j.1365-2958.2012.08115.x"/>
        </citation>
        <scope>REGULON</scope>
    </reference>
    <comment type="alternative products">
        <event type="alternative initiation"/>
        <isoform>
            <id>Q7AKG9-1</id>
            <name>SigR</name>
            <sequence type="displayed"/>
        </isoform>
        <isoform>
            <id>Q7AKG9-2</id>
            <name>SigR prime</name>
            <sequence type="described" ref="VSP_053231"/>
        </isoform>
    </comment>
    <dbReference type="Proteomes" id="UP000001973">
        <property type="component" value="Chromosome"/>
    </dbReference>
    <proteinExistence type="evidence at protein level"/>
    <sequence length="282" mass="30956" checksum="482A1917C58C9858" modified="2012-05-16" version="1">MGSAFCPSRSSRADLDWTVLHAAKTAPIRAAGGPDRRLSSDSSETGLGFTTTSEEMGPVTGTDAGTEHGQAEQPEGRGTGAESTAERSARFERDALEFLDQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRKKQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKQALQAIPEEFRIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGLVPAGAGESNEAKGSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2001-06-01" modified="2022-01-19" version="133" xmlns="http://uniprot.org/uniprot">
    <accession>Q9ACS8</accession>
    <name>Q9ACS8_STRCO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase III subunit alpha</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">dnaE</name>
    </gene>
    <organism evidence="12">
        <name type="scientific">Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)</name>
        <dbReference type="NCBI Taxonomy" id="100226"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Streptomycetales</taxon>
            <taxon>Streptomycetaceae</taxon>
            <taxon>Streptomyces</taxon>
            <taxon>Streptomyces albidoflavus group</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="12">
        <name>SCP1</name>
    </geneLocation>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2002" name="Nature" volume="417" first="141" last="147">
            <title>Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).</title>
            <authorList>
                <person name="Bentley S.D."/>
                <person name="Chater K.F."/>
                <person name="Cerdeno-Tarraga A.M."/>
                <person name="Challis G.L."/>
                <person name="Thomson N.R."/>
                <person name="James K.D."/>
                <person name="Harris D.E."/>
                <person name="Quail M.A."/>
                <person name="Kieser H."/>
                <person name="Harper D."/>
                <person name="Bateman A."/>
                <person name="Brown S."/>
                <person name="Chandra G."/>
                <person name="Chen C.W."/>
                <person name="Collins M."/>
                <person name="Cronin A."/>
                <person name="Fraser A."/>
                <person name="Goble A."/>
                <person name="Hidalgo J."/>
                <person name="Hornsby T."/>
                <person name="Howarth S."/>
                <person name="Huang C.H."/>
                <person name="Kieser T."/>
                <person name="Larke L."/>
                <person name="Murphy L."/>
                <person name="Oliver K."/>
                <person name="O'Neil S."/>
                <person name="Rabbinowitsch E."/>
                <person name="Rajandream M.A."/>
                <person name="Rutherford K."/>
                <person name="Rutter S."/>
                <person name="Seeger K."/>
                <person name="Saunders D."/>
                <person name="Sharp S."/>
                <person name="Squares R."/>
                <person name="Squares S."/>
                <person name="Taylor K."/>
                <person name="Warren T."/>
                <person name="Wietzorrek A."/>
                <person name="Woodward J."/>
                <person name="Barrell B.G."/>
                <person name="Parkhill J."/>
                <person name="Hopwood D.A."/>
            </authorList>
            <dbReference type="PubMed" id="12000953"/>
            <dbReference type="DOI" id="10.1038/417141a"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12">ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="AL589148">
        <property type="protein sequence ID" value="CAC36747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_639831.1">
        <property type="nucleotide sequence ID" value="NC_003903.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_011039523.1">
        <property type="nucleotide sequence ID" value="NC_003903.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1095304"/>
    <dbReference type="KEGG" id="sco:SCP1.224c"/>
    <dbReference type="PATRIC" id="fig|100226.15.peg.8167"/>
    <dbReference type="HOGENOM" id="CLU_001600_0_0_11"/>
    <dbReference type="OMA" id="KQRFHLC"/>
    <dbReference type="PhylomeDB" id="Q9ACS8"/>
    <dbReference type="Proteomes" id="UP000001973">
        <property type="component" value="Plasmid SCP1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041931">
        <property type="entry name" value="DNA_pol3_alpha_thumb_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="11" id="KW-0347">Helicase</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="10">
        <location>
            <begin position="19"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="92"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="CAC36747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000001973"/>
        </source>
    </evidence>
    <sequence length="1213" mass="132858" checksum="7944D3EF7DB503A4" modified="2001-06-01" version="1">MRLHETALGGARLVADSFVHLHNHTEYSMLDGAQKLKPMFAEVDRQGMPAVAMSDHGNMFGAYEFQQVAKGFGSVKPIIGIEAYVAPSSRRNRRQEFWGPGGQRAVSDDGEGSKDVSGGGRFTHMTMWATGAQGLRNLFYMSTEASYTGQFPAGKPRMDMELIAEHAEGVVATTGCPSGAVQTRLRLNQYDEARQVASAYQDIFGKENYFLELMDHGLSIERDVREGLLRLARELSLPLLATNDAHYIHESQADAHDNLLCIGVGKNKADEKRFRFSGSGYYLKTAAEMRALFAELPEACDNTLLIAERVGSYDEVFDNVDEMPQFPDVPDGETQESWLRKEVLTGLAMRYGDPVPTEVLERFETEMSVIGPMGFSSYFLVVADICKYARDNGVPVGPGRGSATGSIVAYATRITELCPLEHGLLFERFLNPERINPPDVDLDFDDRQRDKMVRYVTEKYGDEYTAMVNTFGKIKAKNAIKDSSRILGYPFSHGERITKALPPDIMGKSIPLDGIFDPEHPRHGEAGEIRTMYENEPDVKTVIDTARGVEGLTRGTGVHAAAVILSKTRLTDRIPLHMRASDGVKITGFDYPSCENMGLVKMDFLGLRNLGVIDHAIENIRENRGVRLATVDPMDGDSGTVVIPLDDKKTFELLGRGDTFGVFQLDGGGMRALLKLMEPSRFEDIAAALALYRPGPMAANAHTNYALRQNGKQEPDPIHPELKEVLDPILGSTHHLLIFQEQIMAIARILAGYTLGGADMLRRAMGKKKPEVLAAEWEKFHDGMKANDYSEEAIKAIWDVMLPFSGYAFNKSHTAGYGLVSYWTAYLKANYPAEYMAALLTSVGDDKDKAGIYLADARKLGVTVLPPDVNESVAEFTAVGDDVRFGLRSVRNVGDNVIDTVITARKTKGKFTSFADFLDKADLPALNKRAVESLIKAGAFDSLGHTRRGLCAVHETAIDAVVPLKKAAAYGQDDLFAGLGGGTGDDGESGFGLDVRIDDGEWSRKQLLSTEREMLGMYVSAHPLDGTEHILAAHRDTTIPDLLASGRTEGTVRLSGLITGVQNKVTKQGNAWAIVNLADRDGTIEVLFFPAAYQLVLGALVEDSVISVQGRINDRDGAISIFGQELKVLDVTAAERNGAAPVQLAFPYHRVNEPMVSELRRIMGAHPGESPVHLFVRGPQKTTVYLLRSTVNAATIASDIKGSFGQDTWHGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2001-06-01" modified="2022-01-19" version="116" xmlns="http://uniprot.org/uniprot">
    <accession>Q9AD31</accession>
    <name>Q9AD31_STRCO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dnaN</name>
    </gene>
    <organism evidence="14">
        <name type="scientific">Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)</name>
        <dbReference type="NCBI Taxonomy" id="100226"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Streptomycetales</taxon>
            <taxon>Streptomycetaceae</taxon>
            <taxon>Streptomyces</taxon>
            <taxon>Streptomyces albidoflavus group</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="14">
        <name>SCP1</name>
    </geneLocation>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2002" name="Nature" volume="417" first="141" last="147">
            <title>Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).</title>
            <authorList>
                <person name="Bentley S.D."/>
                <person name="Chater K.F."/>
                <person name="Cerdeno-Tarraga A.M."/>
                <person name="Challis G.L."/>
                <person name="Thomson N.R."/>
                <person name="James K.D."/>
                <person name="Harris D.E."/>
                <person name="Quail M.A."/>
                <person name="Kieser H."/>
                <person name="Harper D."/>
                <person name="Bateman A."/>
                <person name="Brown S."/>
                <person name="Chandra G."/>
                <person name="Chen C.W."/>
                <person name="Collins M."/>
                <person name="Cronin A."/>
                <person name="Fraser A."/>
                <person name="Goble A."/>
                <person name="Hidalgo J."/>
                <person name="Hornsby T."/>
                <person name="Howarth S."/>
                <person name="Huang C.H."/>
                <person name="Kieser T."/>
                <person name="Larke L."/>
                <person name="Murphy L."/>
                <person name="Oliver K."/>
                <person name="O'Neil S."/>
                <person name="Rabbinowitsch E."/>
                <person name="Rajandream M.A."/>
                <person name="Rutherford K."/>
                <person name="Rutter S."/>
                <person name="Seeger K."/>
                <person name="Saunders D."/>
                <person name="Sharp S."/>
                <person name="Squares R."/>
                <person name="Squares S."/>
                <person name="Taylor K."/>
                <person name="Warren T."/>
                <person name="Wietzorrek A."/>
                <person name="Woodward J."/>
                <person name="Barrell B.G."/>
                <person name="Parkhill J."/>
                <person name="Hopwood D.A."/>
            </authorList>
            <dbReference type="PubMed" id="12000953"/>
            <dbReference type="DOI" id="10.1038/417141a"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14">ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <dbReference type="EMBL" id="AL589148">
        <property type="protein sequence ID" value="CAC36640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_639692.1">
        <property type="nucleotide sequence ID" value="NC_003903.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_011039418.1">
        <property type="nucleotide sequence ID" value="NC_003903.1"/>
    </dbReference>
    <dbReference type="SMR" id="Q9AD31"/>
    <dbReference type="GeneID" id="1095197"/>
    <dbReference type="KEGG" id="sco:SCP1.119"/>
    <dbReference type="PATRIC" id="fig|100226.15.peg.8068"/>
    <dbReference type="HOGENOM" id="CLU_038149_1_1_11"/>
    <dbReference type="PhylomeDB" id="Q9AD31"/>
    <dbReference type="Proteomes" id="UP000001973">
        <property type="component" value="Plasmid SCP1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0000318"/>
        <property type="project" value="GO_Central"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="13" id="KW-0347">Helicase</keyword>
    <keyword evidence="13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="126"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="248"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="CAC36640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000001973"/>
        </source>
    </evidence>
    <sequence length="372" mass="39066" checksum="A74B9616F8EB82F2" modified="2001-06-01" version="1">MKLTIDHTAFAAAVSYAVRSLPARPPVPILAGLLLDASSSGLRISAFDYEISADTTAAATVTETGRALVSGRLLSDIVCTVRGDVHLELRGPRLVLKAGSARFILPTLPLDEYPALPEPGTITGTLDGPAFAEAVAQVACAVSREESLPTLTGIGLHHDSEAATLTLYATDRYRFAVRTLSWKDANLPDTSAVIPGRALSDAAKATADDTTVDLALPTGDAGLFTLRSDLTTTAIRALEGELPKYDALFPTEFAHTATVEIAPLKAAAQRVALVSAKKDAPIKLTFTADSTLVLEGGTGDDAQAVDSVDTSLTGGELTIAFNPAFLLDGLNALMAESVQFDFISPTKPAVLRAHDGDDQALRYLLMPIRLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2001-06-01" modified="2022-08-03" version="75" xmlns="http://uniprot.org/uniprot">
    <accession>Q9AD49</accession>
    <name>Q9AD49_STRCO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative plasmid transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">traB</name>
    </gene>
    <organism evidence="2">
        <name type="scientific">Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)</name>
        <dbReference type="NCBI Taxonomy" id="100226"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Actinobacteria</taxon>
            <taxon>Streptomycetales</taxon>
            <taxon>Streptomycetaceae</taxon>
            <taxon>Streptomyces</taxon>
            <taxon>Streptomyces albidoflavus group</taxon>
        </lineage>
    </organism>
    <geneLocation type="plasmid" evidence="2">
        <name>SCP1</name>
    </geneLocation>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2002" name="Nature" volume="417" first="141" last="147">
            <title>Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).</title>
            <authorList>
                <person name="Bentley S.D."/>
                <person name="Chater K.F."/>
                <person name="Cerdeno-Tarraga A.M."/>
                <person name="Challis G.L."/>
                <person name="Thomson N.R."/>
                <person name="James K.D."/>
                <person name="Harris D.E."/>
                <person name="Quail M.A."/>
                <person name="Kieser H."/>
                <person name="Harper D."/>
                <person name="Bateman A."/>
                <person name="Brown S."/>
                <person name="Chandra G."/>
                <person name="Chen C.W."/>
                <person name="Collins M."/>
                <person name="Cronin A."/>
                <person name="Fraser A."/>
                <person name="Goble A."/>
                <person name="Hidalgo J."/>
                <person name="Hornsby T."/>
                <person name="Howarth S."/>
                <person name="Huang C.H."/>
                <person name="Kieser T."/>
                <person name="Larke L."/>
                <person name="Murphy L."/>
                <person name="Oliver K."/>
                <person name="O'Neil S."/>
                <person name="Rabbinowitsch E."/>
                <person name="Rajandream M.A."/>
                <person name="Rutherford K."/>
                <person name="Rutter S."/>
                <person name="Seeger K."/>
                <person name="Saunders D."/>
                <person name="Sharp S."/>
                <person name="Squares R."/>
                <person name="Squares S."/>
                <person name="Taylor K."/>
                <person name="Warren T."/>
                <person name="Wietzorrek A."/>
                <person name="Woodward J."/>
                <person name="Barrell B.G."/>
                <person name="Parkhill J."/>
                <person name="Hopwood D.A."/>
            </authorList>
            <dbReference type="PubMed" id="12000953"/>
            <dbReference type="DOI" id="10.1038/417141a"/>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2">ATCC BAA-471 / A3(2) / M145</strain>
        </source>
    </reference>
    <dbReference type="EMBL" id="AL589148">
        <property type="protein sequence ID" value="CAC36622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="NP_639674.1">
        <property type="nucleotide sequence ID" value="NC_003903.1"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_011039400.1">
        <property type="nucleotide sequence ID" value="NC_003903.1"/>
    </dbReference>
    <dbReference type="GeneID" id="1095179"/>
    <dbReference type="KEGG" id="sco:SCP1.101"/>
    <dbReference type="PATRIC" id="fig|100226.15.peg.8048"/>
    <dbReference type="HOGENOM" id="CLU_1843939_0_0_11"/>
    <dbReference type="OMA" id="MRANADR"/>
    <dbReference type="Proteomes" id="UP000001973">
        <property type="component" value="Plasmid SCP1"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="CAC36622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000001973"/>
        </source>
    </evidence>
    <sequence length="137" mass="14794" checksum="76AB51E2EC60E810" modified="2001-06-01" version="1">MSDLAPTTGGAAARTDGDNRYKAVQQKLKTLSTALQLAGDELEQLLRGMRQNAQRAEGLAVDIANAELDRKFIEMTNQVAVALGGAAVEVQKVHETAQEVSGLATDARRTHARLYEGLDTVRSGRSERTPKPGFFAR</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>