<?xml version="1.0" encoding="UTF-8"?>
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<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBB3</accession>
    <name>A0A2H5VBB3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">eIF2_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HRbin05_00001</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73973">
        <property type="protein sequence ID" value="GBC73973"/>
        <property type="gene ID" value="HRbin05_00001"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015256">
        <property type="entry name" value="eIF2g_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09173">
        <property type="entry name" value="eIF2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eIF2_C" evidence="4">
        <location>
            <begin position="2"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF09173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC73973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="63" mass="6862" checksum="912A297FA1F461A9" modified="2018-02-28" version="1">MKVNESLRLNIGTAAVLATVKSVHDGRLNVKLKRPVCAIAKSRVAISRRIADRWRLIGAGVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBD9</accession>
    <name>A0A2H5VBD9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S19e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps19e</name>
        <name evidence="5" type="ORF">HRbin05_00043</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">May be involved in maturation of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74012">
        <property type="protein sequence ID" value="GBC74012"/>
        <property type="gene ID" value="HRbin05_00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01474">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001266">
        <property type="entry name" value="Ribosomal_S19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027548">
        <property type="entry name" value="Ribosomal_S19e_archaeal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018277">
        <property type="entry name" value="Ribosomal_S19e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11710">
        <property type="entry name" value="PTHR11710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01090">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01413">
        <property type="entry name" value="Ribosomal_S19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00628">
        <property type="entry name" value="RIBOSOMAL_S19E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="151" mass="17042" checksum="4F268C2D6AF5F05B" modified="2018-02-28" version="1">MVKAYDVPADRLIARLAATLKQDQNIVPPPWARFVKTGCHAMRLPYDRDWWYVRCASLLRKIYIHGPIGLSDLRSEYGGRQRRGSSPSHHRDAGGAIIRKALHQLEQAGYVMKIHGKGRVLTSKGMSLVDSTANEVFNELVKIMPELSKYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBF9</accession>
    <name>A0A2H5VBF9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
            <shortName evidence="5">CDG synthase</shortName>
            <ecNumber evidence="5">4.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Archaeosine biosynthesis protein QueE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">queE_1</name>
        <name evidence="5" type="synonym">queE</name>
        <name evidence="7" type="ORF">HRbin05_00028</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:27974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="EC" id="4.3.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </cofactor>
        <text evidence="5">Binds 1 S-adenosyl-L-methionine per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74000">
        <property type="protein sequence ID" value="GBC74000"/>
        <property type="gene ID" value="HRbin05_00028"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00917">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024924">
        <property type="entry name" value="7-CO-7-deazaguanine_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="18"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="37"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="238" mass="27202" checksum="B5BC8AF8B6192EB6" modified="2018-02-28" version="1">MRVSISEVFTSIEGEGIYLGTKTLFIRLAGCPLRCFYCDTPYALSIGNGTYYSIDEAKTIIARKVERGTFKANFTGGEPLLQHEAVRELARYVRDELLLKTYLESSCYDASRFLHVLPYIDICKIEFKLKDSNAIDDKHYTRLLENEMLCLRHAIASRKVTYIKVVLSSLSKREEVEELARMIFEGDTSKAIDGFVLQPVNGVNEPTLEHMLAMYDAVHQYYPNVRIIPQMHKVMGIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBG4</accession>
    <name>A0A2H5VBG4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Branched-chain-amino-acid aminotransferase</fullName>
            <shortName evidence="14">BCAT</shortName>
            <ecNumber evidence="14">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14 15" type="primary">ilvE</name>
        <name evidence="15" type="ORF">HRbin05_00054</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 14">Acts on leucine, isoleucine and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 14">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 14">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 14">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 14">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 13">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="14"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74023">
        <property type="protein sequence ID" value="GBC74023"/>
        <property type="gene ID" value="HRbin05_00054"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005785">
        <property type="entry name" value="B_amino_transI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01122">
        <property type="entry name" value="ilvE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 14" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="14 15" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="12 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14 15" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00003109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU364094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="GBC74023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="238" mass="26627" checksum="275C99F6F8918A04" modified="2018-02-28" version="1">MDLRYGFDEMIDAVIETVKVNGLRSCYIRPIAYYSYGKMGVNPLPNRVDVAIAIWQWDEYLSSEQGIRCMVSSWRRIDARTMPVGAKATANYANSALARIEALKNGFDEAIMLNINGMVAEASAENVFIVRDGVICTPPTTDGALAGITRDTVLQIAKHEGIMYEVRSISRDELYLADEVFLTGTAAGIKPVVMIDNRKVGDGNVGVITKRLKSMYEDVVRGRDERFIKWLTYVEMYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBH3</accession>
    <name>A0A2H5VBH3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74037">
        <property type="protein sequence ID" value="GBC74037"/>
        <property type="gene ID" value="HRbin05_00068"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="217" mass="25214" checksum="D34CE77B2421F783" modified="2018-02-28" version="1">MNRLVQLEHSKSCPLCKGNLLHAVDGEIICSRCGAVLGYSNNNDDSIIRYRRIEPNLYNAVHVGTEAYLSRSARFYSSSKDEQLLSLFSNLCERLSLPWNIAFECWSYYSKLLKCVKMGSAELAMLVVYTVCNRYSLRKSQEEIRDAVELVYARRYLPTIQRILLNFANEVYRCKDANMVEMYMHFLDIDERARRRARKILSIINNVNLKKVMNVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBI4</accession>
    <name>A0A2H5VBI4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00061</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74030">
        <property type="protein sequence ID" value="GBC74030"/>
        <property type="gene ID" value="HRbin05_00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="201" mass="22335" checksum="DB640B70ABBFA9F3" modified="2018-02-28" version="1">MYAGAFTFLGVAVMLLISTYIMGSIPMFGRAEVTIQAGPSVEYVKRLPEKIKAIEREVGTETCYYHGICGMELFNYDGIAIPIDDSIIAKFPRADEFRKAFKVLEERHLDPDECGGGPLRGSADICDTANMYEFEIGKSDADALKSIMKELALQHGKSKDGRSAVVWDYGLNREIVTQGMVITVKYNDIYYNIGVAIYSMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBM4</accession>
    <name>A0A2H5VBM4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Muconolactone Delta-isomerase</fullName>
            <ecNumber evidence="2">5.3.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">catC</name>
        <name evidence="2" type="ORF">HRbin05_00101</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.4" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74070">
        <property type="protein sequence ID" value="GBC74070"/>
        <property type="gene ID" value="HRbin05_00101"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016159">
        <property type="term" value="F:muconolactone delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026029">
        <property type="entry name" value="MLI_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02426">
        <property type="entry name" value="MIase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="86" mass="10081" checksum="2A969DD32F447EB5" modified="2018-02-28" version="1">MKFLILWSFKKVALTPDLVRAVLDMRIYAKRLKDDGKLEAYYHIVGRHGGAWILNVESNDELENLIAGMPVYNYAEYEIYPLTEMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBM9</accession>
    <name>A0A2H5VBM9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Teichoic acid glycerol-phosphate transferase</fullName>
            <ecNumber evidence="6">2.7.8.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tarF</name>
        <name evidence="6" type="ORF">HRbin05_00128</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-glycerol glycerophosphotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.-" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74095">
        <property type="protein sequence ID" value="GBC74095"/>
        <property type="gene ID" value="HRbin05_00128"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047355">
        <property type="term" value="F:CDP-glycerol glycerophosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007554">
        <property type="entry name" value="Glycerophosphate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043149">
        <property type="entry name" value="TagF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04464">
        <property type="entry name" value="Glyphos_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0777">Teichoic acid biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="382" mass="45857" checksum="7513EE45FB5C1AC9" modified="2018-02-28" version="1">MILNFMLTILSYIIPKDRNLILLGSYNTFAGNTKTFYLYCLSKARNNFKIYWITHNKCIYRLLVNRQLPVLYIYTLDAFIHILRARYLLLTHGPIDISYFYFLFGKFNMIQTWHGIALKDITPTAEQKAPLYMRIINYFSRLTDRNYKLILATSEDTRRIFISAFNNENVKIIGYPRNDVFYNKELLYEDYREKLHLYNFSKVILYCPTFRENPTLQPFSNDFLNVLNEYLKFNNFIMLIKRHPYDNFLLNSINESHLSNIIDISAIVIDVQDLLPHVDILITDYSSILFDFPLLDRPIIFYPYDINLYTEKCRSLNYDYFEELPGPFATNEKELLEVIKRIDIIGMDDSYREKYKTFKRKFHYYDDGKACERLLDYLLKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBN4</accession>
    <name>A0A2H5VBN4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="1">2.7.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cysC_1</name>
        <name evidence="2" type="ORF">HRbin05_00130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the APS kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74097">
        <property type="protein sequence ID" value="GBC74097"/>
        <property type="gene ID" value="HRbin05_00130"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="126" mass="14416" checksum="6F22CA5FAA06AA3D" modified="2018-02-28" version="1">MKGFTVWLTGLSGSGKTTIGRTLQHRLINLGYRAELLDGDEVRRNLSPDLGFSKQDRELHARRVVYISKLLTRNGIIAIVSLISPYRAFRAYAREELKDFVEVYVKCSINTCIKRDPKGLYRKALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBN7</accession>
    <name>A0A2H5VBN7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00136</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74103">
        <property type="protein sequence ID" value="GBC74103"/>
        <property type="gene ID" value="HRbin05_00136"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="72" mass="8587" checksum="FE2332491EB8F92B" modified="2018-02-28" version="1">MDKIQVSISKGLYEEIKKRFSCKDSKFSSIDEYIEYLLLYAMNNISDEQKLAKSIDEEEEELKERLKRLGYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBP6</accession>
    <name>A0A2H5VBP6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00146</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74113">
        <property type="protein sequence ID" value="GBC74113"/>
        <property type="gene ID" value="HRbin05_00146"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000892">
        <property type="entry name" value="Ribosomal_S26e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038551">
        <property type="entry name" value="Ribosomal_S26e_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12538">
        <property type="entry name" value="PTHR12538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01283">
        <property type="entry name" value="Ribosomal_S26e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="95" mass="10560" checksum="A582043FB3AC9F3C" modified="2018-02-28" version="1">MTKKRSNRGRSKGGKGHSSLVQCTNCGRWVPRDKVKKVTSRLSLVDPSLAKELRASGAYIASPTVIKYYCVSCAVYYGVVKVRAEDERKSPEPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBQ7</accession>
    <name>A0A2H5VBQ7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00159</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74126">
        <property type="protein sequence ID" value="GBC74126"/>
        <property type="gene ID" value="HRbin05_00159"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="174" mass="19607" checksum="1F06C1FDF1B4416A" modified="2018-02-28" version="1">MDKGMDTNYKKSAYNSNNIIKIATILQKSLNNGKCSSTEMREVSRYIMQYTRANLEDCIKGLDEIIRNSKDDRLGDVQSTLQRILHDVKGIARAYEHVIAENGSVDKAILAALINIDNEMTSNLKLLNNHIASIKGTEINENEIKELSFLAGEIELNIKERGELIKKLELKGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBR0</accession>
    <name>A0A2H5VBR0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pectate_lyase_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74100">
        <property type="protein sequence ID" value="GBC74100"/>
        <property type="gene ID" value="HRbin05_00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024535">
        <property type="entry name" value="Pectate_lyase_SF_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12708">
        <property type="entry name" value="Pectate_lyase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pectate_lyase_3" evidence="1">
        <location>
            <begin position="45"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="583" mass="64663" checksum="3CD6D9FC6502301B" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBR3</accession>
    <name>A0A2H5VBR3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA polymerase sliding clamp</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Proliferating cell nuclear antigen homolog</fullName>
            <shortName evidence="3">PCNA</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pcn</name>
        <name evidence="8" type="ORF">HRbin05_00052</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Sliding clamp subunit. Responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the PCNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74021">
        <property type="protein sequence ID" value="GBC74021"/>
        <property type="gene ID" value="HRbin05_00052"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030337">
        <property type="term" value="F:DNA polymerase processivity factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00317">
        <property type="entry name" value="DNApol_clamp_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000730">
        <property type="entry name" value="Pr_cel_nuc_antig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022649">
        <property type="entry name" value="Pr_cel_nuc_antig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022648">
        <property type="entry name" value="Pr_cel_nuc_antig_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11352:SF0">
        <property type="entry name" value="PTHR11352:SF0"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02747">
        <property type="entry name" value="PCNA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00705">
        <property type="entry name" value="PCNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00339">
        <property type="entry name" value="PCNACYCLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 3 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCNA_N" evidence="6">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="PCNA_C" evidence="7">
        <location>
            <begin position="164"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="287" mass="32023" checksum="D1A8AA25FC0015E5" modified="2018-02-28" version="1">MLIARSKSAEEWKTIVSAISTIVEEATFEATSEGISFRGMDPSHVALIDVQLLNSAFEYYKCDGSIRFAVRVDEFLKLLKRAGKEDSIEVSIGGAGAVGESRRERGEEEVEEEGEVTALEESKEKEMVALASDENMLSIKMVSKYTRQYKMRLIESTSSSTPLPKITFNTKVVMKMAQFIEALKDVEIVSDYITMRCDGNMLQLIGKGDSGDAVITFNKGDEGVEEMSSNGESNATYSLEYLGSIVKAVDNADSIVIEYSTRMPLRLEFKMPYMCRIYFYLAPRVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBR7</accession>
    <name>A0A2H5VBR7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative [LysW]-lysine/[LysW]-ornithine hydrolase</fullName>
            <ecNumber evidence="2">3.5.1.130</ecNumber>
            <ecNumber evidence="2">3.5.1.132</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">lysK</name>
        <name evidence="4" type="ORF">HRbin05_00169</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[amino-group carrier protein]-C-terminal-gamma-(L-lysyl)-L-glutamate + H2O = [amino-group carrier protein]-C-terminal-L-glutamate + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:48684"/>
            <dbReference type="Rhea" id="RHEA-COMP:9693"/>
            <dbReference type="Rhea" id="RHEA-COMP:9715"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:78525"/>
            <dbReference type="ChEBI" id="CHEBI:78526"/>
            <dbReference type="EC" id="3.5.1.130"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[amino-group carrier protein]-C-terminal-gamma-(L-ornithyl)-L-glutamate + H2O = [amino-group carrier protein]-C-terminal-L-glutamate + L-ornithine</text>
            <dbReference type="Rhea" id="RHEA:52676"/>
            <dbReference type="Rhea" id="RHEA-COMP:9693"/>
            <dbReference type="Rhea" id="RHEA-COMP:13328"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:78525"/>
            <dbReference type="ChEBI" id="CHEBI:136763"/>
            <dbReference type="EC" id="3.5.1.132"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="2">Binds 2 Zn(2+) or Co(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M20A family. LysK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.130" evidence="2"/>
    <dbReference type="EC" id="3.5.1.132" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74136">
        <property type="protein sequence ID" value="GBC74136"/>
        <property type="gene ID" value="HRbin05_00169"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00039"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01120">
        <property type="entry name" value="LysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010175">
        <property type="entry name" value="LysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01902">
        <property type="entry name" value="dapE-lys-deAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0170">Cobalt</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="159"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="368" mass="39841" checksum="AD45FAEA88492BD9" modified="2018-02-28" version="1">MVTVSNSYAIELLKQALELYTPSKQEYPLARLIAEKASSELGFEHVHMDDVGNVIARKGYGSPRVLLCGHMDTVPGYIPVSIRDGLIYGRGASDAKAPLLALLLAASLARDCGTITFAGLVDEEGNATGIKNLMRDSIDADYAIFGEPSGLEKITIAYKGRVALNITCDVGDSAHASAPMLAGNAIEEAYELWQSIKDALASMNNKGLTYCITEIKGGSSHNVTPARCSLTIDIRVPNGLSTLNVLNLLDLTLNRVAEKKGIKVEYSIEDRTEAFEARHDSPLVRALVLAVMDVRGKRPMLIRKSGTGDMNILGNALNIPIVTYGPGDAHSSHSADEHVSIDEYIASIDVLKRTLYHLSRLHKREIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBS2</accession>
    <name>A0A2H5VBS2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin reductase</fullName>
            <ecNumber evidence="2">1.8.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trxB_1</name>
        <name evidence="2" type="ORF">HRbin05_00062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74031">
        <property type="protein sequence ID" value="GBC74031"/>
        <property type="gene ID" value="HRbin05_00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="322" mass="35518" checksum="8DA896B266FE46E7" modified="2018-02-28" version="1">MHHDIIVVGGGVAGLSAALFIARQGSDVLVLSQDLGGQLNLIPKLENYPGIILTSGELLARTLEQQVLTFGGKIRYERVESVDAIDDGFKVISNEREYTCKALILALGKVPRELGVEGERRFLGRGLTYATKSEAPFYQGRMVATTGVGNYLVESALLLSRFARKVYVIYRTSKMAGDKEMIEALERKDNIEYVPNSEVIALDGDERLRSITIRDQSGGTKRLEVDGLFVEMGYKVYIEFVKHLVRINQRGEIEVNEYCETSYKGIFAAGDATSVPYKQVIVAAGEGAKAAISAYNYLQRLAGKPGIKADWRKSIGAQVYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBU0</accession>
    <name>A0A2H5VBU0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00189</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74155">
        <property type="protein sequence ID" value="GBC74155"/>
        <property type="gene ID" value="HRbin05_00189"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="87" mass="9776" checksum="66746976E8BB9466" modified="2018-02-28" version="1">MKRVKEEVIDRGVEVFKAESQRGDLIQIFEINGNPAMGWEAGDKNSLVILDGKVISSEPSSYPAVVAMIDQKELFTMVLVVMYQWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBU3</accession>
    <name>A0A2H5VBU3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Chorismate pyruvate-lyase</fullName>
            <ecNumber evidence="1">4.1.3.40</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00082</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.40" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74051">
        <property type="protein sequence ID" value="GBC74051"/>
        <property type="gene ID" value="HRbin05_00082"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008813">
        <property type="term" value="F:chorismate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002800">
        <property type="entry name" value="Rv2949c-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01947">
        <property type="entry name" value="DUF98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="192" mass="21751" checksum="E5026B6C5F41ACDA" modified="2018-02-28" version="1">MIKQVSVEVGSGDFGTSMLSALKKLEDAACIKLSRIEKLLLAEVGTVEQLLSILVDAPVSVDVVRQEEVGKVIEREVNIRKAYSDEILLDAKSIINVDVLPDGVVCDIRAKRLGIGSVIMKHRLETFRRIVEIGCYYSNDESKYGKGEDEDEDKERVLRVYRLYSIFYVGTEAFRIREEFRSSVIRRLASFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBV0</accession>
    <name>A0A2H5VBV0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATP phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisG</name>
        <name evidence="9" type="ORF">HRbin05_00199</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74165">
        <property type="protein sequence ID" value="GBC74165"/>
        <property type="gene ID" value="HRbin05_00199"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="7">
        <location>
            <begin position="48"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="8">
        <location>
            <begin position="240"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="324" mass="36903" checksum="F2FF1B594E20EB7F" modified="2018-02-28" version="1">MIKFAIPKGSIEEATYRFIEQAWFSLHGKGRSYRVRVNDPEIQMKILRPQEIPTFVSNGLYDIGITGKDWVTETSADVKVMLDLEYGWVRLVYAIPKSSNYNTLAEMLKDYADKGRTLRISTEYLNISSKYIMGNEEYKRLYGDKEPMVITPWWSNGSNSKVQIILSFGATEAKPPEDTDAIIDITETGTTLEQNNLKPVESIMESTAVLIANKESLKDPKKRVKIYDVLTLLKGVVDSRKKLHIFANVKAENLQELLKSLPALKRPTVSPLSEEGWYAVNTVISKDEFVRILPMLRRLAQGLVVHEPRQILALEEIMKDEEST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBV2</accession>
    <name>A0A2H5VBV2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="4">IGPD</shortName>
            <ecNumber evidence="4">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">hisB</name>
        <name evidence="5" type="ORF">HRbin05_00203</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74169">
        <property type="protein sequence ID" value="GBC74169"/>
        <property type="gene ID" value="HRbin05_00203"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="195" mass="21526" checksum="0BCE7683907595F7" modified="2018-02-28" version="1">MQEKERRSRVERYTNETSVEVEVDLDGNGLYSVETGIRFLDHMIASISKHSLIDIRLKGVSKDGIRHHLIEDVAITLASALDKALGGRDGIERFGYAMVPMDDALAFVALDLVRRAYHAIDLKLVNGVEDMVKEDIEHFFTSFALNLNACIHVVVQYGSNDHHKVEAACKALGVALRNAAVINPRKGIASTKGTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBV4</accession>
    <name>A0A2H5VBV4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Release factor glutamine methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.297</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prmC</name>
        <name evidence="4" type="ORF">HRbin05_00092</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic/archaeal PrmC-related family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74061">
        <property type="protein sequence ID" value="GBC74061"/>
        <property type="gene ID" value="HRbin05_00092"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004557">
        <property type="entry name" value="PrmC-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00537">
        <property type="entry name" value="hemK_rel_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTS" evidence="3">
        <location>
            <begin position="35"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="212" mass="23004" checksum="C27950A824DC69B4" modified="2018-02-28" version="1">MDQQNNKGGGMKEEKDDNDNGYSSDIYNPAEDTFMLASAVDGLHGDDALEIGTGSGYIASILSKGFKRVVATDISLEALIYAKSSNYSSGDVEFVCCNSADAISGISFDLIAVNPPYLPSERIEDATVDGGRYGIEVAMSMLKSASRLLRDDGRIIMVISSLARYDLLLSSLHGIGLEGRITARKRYGFEDLLLIEMRSIKHAAQQHQDHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBW6</accession>
    <name>A0A2H5VBW6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00211</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74177">
        <property type="protein sequence ID" value="GBC74177"/>
        <property type="gene ID" value="HRbin05_00211"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="71" mass="8070" checksum="918B65AD4984E66F" modified="2018-02-28" version="1">MGIFDKGKDRCSICGSKITFPYRLERYGIPGFVCGKCYDERLREIYGIDLSRREESKESKQQGLGLGLSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBX4</accession>
    <name>A0A2H5VBX4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="3">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="3">PPC decarboxylase</shortName>
                <shortName evidence="3">PPC-DC</shortName>
                <ecNumber evidence="3">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="3">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="3">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="3">PPC synthetase</shortName>
                <shortName evidence="3">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">coaBC</name>
        <name evidence="7" type="ORF">HRbin05_00227</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme A biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="3"/>
    <dbReference type="EC" id="6.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74193">
        <property type="protein sequence ID" value="GBC74193"/>
        <property type="gene ID" value="HRbin05_00227"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="5">
        <location>
            <begin position="18"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="6">
        <location>
            <begin position="191"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="3">
        <location>
            <begin position="196"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="407"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="428" mass="46589" checksum="CA71417D81BF1CCF" modified="2018-02-28" version="1">MHPSKEIIGSHGDELKGKRIVLCVTASIAAYKAVDLARLLMRHGADVYPVLTRKATKLVGSELLSWATGNRAVVDLTWELEHIQLADKDRADLIIIYPCTANTLSKIANGIDDTSVTTVASVALGSRIPIIIALAMHEVMYHNPMVARNVRALQGIVEFVDPVIEEGKAKVAEPEHVLAKAIEVLKRRALLKGKSILITAGATVEHIDNVRVITNLSSGRFGTAFAREAMLMGADVTLIYGHGSSEPPPNVRTIKVSTSKDMLNALTNELRSKHYDAVVMNAAVADFRPAQVSSSKIESRDSNGLMLRLEPTEKIVDVVKMLSPDTFLIAFKADDCSREELIAKAKAKLQECRGDIVVANYASRSISKDGCDAVIVSSDGSIMDLHGRKDDVARRILAYMAERMASLSSQSPLSSSQQQQQQNKNDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBY2</accession>
    <name>A0A2H5VBY2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Xaa-Pro dipeptidase</fullName>
            <ecNumber evidence="5">3.4.13.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pepQ</name>
        <name evidence="5" type="ORF">HRbin05_00229</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.9" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74195">
        <property type="protein sequence ID" value="GBC74195"/>
        <property type="gene ID" value="HRbin05_00229"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102009">
        <property type="term" value="F:proline dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="4">
        <location>
            <begin position="6"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="3">
        <location>
            <begin position="136"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="360" mass="41005" checksum="C77BB402A2D2F558" modified="2018-02-28" version="1">MSEESRSRRVLDEAYRMGCSTVIAFEPEDVFYLTGFWGEGIVVLNQSDTRLIVPQLEADRARSIARCEVLEAERGSSMLDKALSFVAEDANVCTDCNDHSIFERMRVKLVDSSRLRYSKDIFYNARKVKDEYEIRMIEHAARILDELFKVCEYVIRTGLSERQIQAMLMYEAMRRGAYPPSYRYTLSPLIVASGTNSSLPHAEPSDRILSMGDLVTVDLTLRYGGYIADATRTFALGSIDREKEDIYHIVREAQERALEAVHDDVECREVDGAARAYIEGKGYGERFIHSTGHGIGLDVHEPPWISRNSQERLARGMCITIEPGIYIANRYGVRIEDSLAISRDGRVVVMNRYTKDLIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBZ4</accession>
    <name>A0A2H5VBZ4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00248</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74213">
        <property type="protein sequence ID" value="GBC74213"/>
        <property type="gene ID" value="HRbin05_00248"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007153">
        <property type="entry name" value="Adenosine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036902">
        <property type="entry name" value="Ta1353-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36155">
        <property type="entry name" value="PTHR36155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04008">
        <property type="entry name" value="Adenosine_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103165">
        <property type="entry name" value="SSF103165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="160" mass="17864" checksum="03B040A31F4AAC10" modified="2018-02-28" version="1">MNILSVRLEAPPNTNMIVGQAHFIKTVEDMYEMLVSSSPTIRFGIAFCEASGKALIRYDGNDDMLVRKAIEFASMISAGHVFVLLISNAYPINILNRVKMMDEVACIYCATANPVELIIVETEQGRGVLGVVDGVKSKGVESDEDRRERHELLRRLGYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC03</accession>
    <name>A0A2H5VC03_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate cyclase 1</fullName>
            <ecNumber evidence="3">4.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cyaA</name>
        <name evidence="3" type="ORF">HRbin05_00253</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74218">
        <property type="protein sequence ID" value="GBC74218"/>
        <property type="gene ID" value="HRbin05_00253"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="92"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="279" mass="31119" checksum="B4A0713BF55AD563" modified="2018-02-28" version="1">MNVGSNGVEENRDNTNGGERARGGDGRMVTEDIINIIMGELSSTRVVDTQTYIAEVQARMWKALKRGMHFKALTRSSEEFLKRHLNSKVKLVVLYADMVGSTRLSRMLPVERLATIIQAYSQEMSLIALNFDGLVLKYVGDAVIAYFPATHNLLLAADDAVNCAVAMIEVLRQGINPVLLQYDYPELAMKVSMDVGEHSVIQYGSDKSMDVDVVGYGISMAAKIHALAESNSIVISHNVYDVLHPNMQSRFKQLNLDISKWGYTDEDSGELYKVYIYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC10</accession>
    <name>A0A2H5VC10_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Periplasmic pH-dependent serine endoprotease DegQ</fullName>
            <ecNumber evidence="7">3.4.21.107</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">degQ</name>
        <name evidence="7" type="ORF">HRbin05_00234</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.107" evidence="7"/>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74200">
        <property type="protein sequence ID" value="GBC74200"/>
        <property type="gene ID" value="HRbin05_00234"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001193">
        <property type="entry name" value="MBTPS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13325">
        <property type="entry name" value="PTHR13325"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01000">
        <property type="entry name" value="SREBPS2PTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="225"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="401" mass="43919" checksum="A334D55D0CD70700" modified="2018-02-28" version="1">MVFGDNTSIVALLLAWVIIIASAKALRLEKRGFEIKPFMLTYKNHAVSSTLDRLLAINRSAVRAFADVSIVAGAIMMVFAVWFLLNNLIHFFADSGKFSEVTLLIPGVTIRSVPNLVYFLLAAPIVLVVHEVAHGIVARLERIKVKSGGFAIIIALIAGFVEPDEDEFNRARRVSKVRVIAAGSTSNILLSFLVASLLMFNPAFGNILELLSPQVRSIFYNDPLGVPVVQVIEGSGAAQAGMRAGDIITAINDTQVKTPADLARVKLVPGEQVSVSILRDGEPMRLTVTVMGAEDDPNRGMIGIIRDVFPYMPPKVPFWIPWPHEVFMFLLWLWMLSFFIGIFNMLPMIPLDGEKYVSSMLEKRVSARSLKATRIGINALGFGLLGANIIATVIKSGFITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC25</accession>
    <name>A0A2H5VC25_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elp3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74246">
        <property type="protein sequence ID" value="GBC74246"/>
        <property type="gene ID" value="HRbin05_00281"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Elp3" evidence="1">
        <location>
            <begin position="268"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="575" mass="65616" checksum="3822CC44A960C1C8" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC29</accession>
    <name>A0A2H5VC29_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HRbin05_00164</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SEC61-beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74131">
        <property type="protein sequence ID" value="GBC74131"/>
        <property type="gene ID" value="HRbin05_00164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016482">
        <property type="entry name" value="SecG/Sec61-beta/Sbh"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03911">
        <property type="entry name" value="Sec61_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="57" mass="6111" checksum="67C0DCBBFA773770" modified="2018-02-28" version="1">MSVRKSKKGAPLPASSAGLLRFFEDETKGIKVRPEIVFAVASGLIGISILIKILFPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC34</accession>
    <name>A0A2H5VC34_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">High-affinity zinc uptake system membrane protein ZnuB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">znuB</name>
        <name evidence="7" type="ORF">HRbin05_00282</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74247">
        <property type="protein sequence ID" value="GBC74247"/>
        <property type="gene ID" value="HRbin05_00282"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="278" mass="29763" checksum="BC1213F0D71D0AA3" modified="2018-02-28" version="1">MLDILAYTFMQKALITGIAISAACSILGLFLVLKRYSLFGDALSHVALSGVAIGLFLNIYPLWTALLTSVTASLGITRLRQSIRIQGDALIAVLLIFGVAFAVLLISASGGFRADLFSYLFGSITLISNEDALTAVIASLAIVASVIALKDKLFYMALDERQAKISGLNTTLLNYIFMIMASIMVIVAMRLVGILLVSSLIVLPNIAAMMLGRGFKTTMLISLCISLASVISGIITSYYLNVATSGMIVMICIGIMVSIIISKHLKIPRSEQNVLDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC52</accession>
    <name>A0A2H5VC52_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00309</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74273">
        <property type="protein sequence ID" value="GBC74273"/>
        <property type="gene ID" value="HRbin05_00309"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="33" mass="3446" checksum="480A9AAECA653C09" modified="2018-02-28" version="1">MIAKVMHTGGGSQAWPKMLAVDARDLSSCDVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC74</accession>
    <name>A0A2H5VC74_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplF</name>
        <name evidence="3" type="synonym">rpl6</name>
        <name evidence="5" type="ORF">HRbin05_00326</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74288">
        <property type="protein sequence ID" value="GBC74288"/>
        <property type="gene ID" value="HRbin05_00326"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_A">
        <property type="entry name" value="Ribosomal_L6_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019907">
        <property type="entry name" value="Ribosomal_L6P_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03653">
        <property type="entry name" value="uL6_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="4">
        <location>
            <begin position="20"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="4">
        <location>
            <begin position="108"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="192" mass="21042" checksum="A267ACA1799DABB5" modified="2018-02-28" version="1">MSISKESVKESIALEAVVDVPDGVQVSMNGRTLEVKGPKGKVSKDLSKIHVDIRVDGSSVRIRPLLARGKPRRKDKAIVNTMHSIVRNMIEGVLHGYTYKLKIVHAHFPISVKVKGKQVLIENFIGERSPRVAEIVGDCKVSVEGEDVIVKGISLEDVAQTAANIENATSIKGKDIRVFLDGIYIYAKEKGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC75</accession>
    <name>A0A2H5VC75_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease P protein component 1</fullName>
            <shortName evidence="6">RNase P component 1</shortName>
            <ecNumber evidence="6">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Rpp29</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnp1</name>
        <name evidence="7" type="ORF">HRbin05_00334</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Consists of a catalytic RNA component and at least 4-5 protein subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the eukaryotic/archaeal RNase P protein component 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74296">
        <property type="protein sequence ID" value="GBC74296"/>
        <property type="gene ID" value="HRbin05_00334"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00754">
        <property type="entry name" value="RNase_P_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036980">
        <property type="entry name" value="RNase_P/MRP_Rpp29_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023538">
        <property type="entry name" value="RNP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023534">
        <property type="entry name" value="Rof/RNase_P-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002730">
        <property type="entry name" value="Rpp29/RNP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01868">
        <property type="entry name" value="RNase_P-MRP_p29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00538">
        <property type="entry name" value="POP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101744">
        <property type="entry name" value="SSF101744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="102" mass="11853" checksum="87F3EEDB93993C2B" modified="2018-02-28" version="1">MRLREDNIFAHELIGLELVVEESSDPTLQGLHGKVVFESKNMLYVKVDEADRYRVKALPKAIVRLVFTLPDGVRCKVEGKDLIGRPEDRIERIERVMRHGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC88</accession>
    <name>A0A2H5VC88_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00347</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74309">
        <property type="protein sequence ID" value="GBC74309"/>
        <property type="gene ID" value="HRbin05_00347"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="84" mass="8985" checksum="40685B2DC64683B8" modified="2018-02-28" version="1">MNFSKKGMVGVVLALAGLMSVVYAQEGGGEDEHHALCEVERDREITLTLSQSSGLLGSTITAEMSVTLVGEDKPRGWRDAVCMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC95</accession>
    <name>A0A2H5VC95_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00346</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74308">
        <property type="protein sequence ID" value="GBC74308"/>
        <property type="gene ID" value="HRbin05_00346"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="101" mass="10638" checksum="426C629F54EB3BFA" modified="2018-02-28" version="1">MQFAWIDSYTIIGDGLVSVVGGAGNPFAGYGTCSVPAGETSTGYATATLMADVELGTTTGYGMCWISIWTRDMHWYDFTVEPFMVVPETVLGIGVVAALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC96</accession>
    <name>A0A2H5VC96_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">glyA</name>
        <name evidence="10" type="ORF">HRbin05_00345</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.-" evidence="7"/>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74307">
        <property type="protein sequence ID" value="GBC74307"/>
        <property type="gene ID" value="HRbin05_00345"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="19"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="129"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="382"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="452" mass="50177" checksum="2189F1E0C8202128" modified="2018-02-28" version="1">MVASNENGNDEAYKHYSNVLRLLREHHSWFNRCIPLIASENVPSPAVREAIVSDFANRYAEGWPGERVYAGCIYIDQVELICIELAKRVFRAEFADVRPVSGVVANLAVYAAFTEPSDTMLALAIPNGGHISHGKREHSGTAGLVRGLQVETFAFNKEEMNIDVDATIKKVEEMKRNSNDSKVPKLAMFGASLFLFPHPVKELADYLRSNNITICYDAAHVAGLIAGNEFQDPLREGADVMTMSTHKTLFGPQGGMILSFEKYAESIKKAVFPGNTSSHHLHNVAGKAIALAEMLAFGRDYARQVVRNAKALAEALYNLGFDVLGAKHGFTRSHQVAVDVSRYGDGGSIEQMLERAGIICNRQLLPGDIKAGRNYKHPGGIRLGTSEVTRLGMREQDMVEIARFIKRVVVDREEVSKVANDVMELRKDFQKVHYAFDDNVGAYEYISLVKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCA9</accession>
    <name>A0A2H5VCA9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00367</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74329">
        <property type="protein sequence ID" value="GBC74329"/>
        <property type="gene ID" value="HRbin05_00367"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="190" mass="20918" checksum="6009711C9B1C2A5D" modified="2018-02-28" version="1">MIEKGIALAIEGMHGKKVDEMEVKALMELANRTMTRFPFRLPKQLALYMRMASLLEGIYLTLKVDFQFMRVLSSLLQEEGLIRDAYIEEVKSSIESIVRGLQDYIAVAPMLRDYLERSLMEGSSSSSSRSGRLGYRTRLSSSATLIAGSIVTSSLLISSAIIMESNPTLGQIGFAAAAMAIGVMLIARKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCB3</accession>
    <name>A0A2H5VCB3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Methyl-accepting chemotaxis protein 4</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mcp4</name>
        <name evidence="9" type="ORF">HRbin05_00374</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74336">
        <property type="protein sequence ID" value="GBC74336"/>
        <property type="gene ID" value="HRbin05_00374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="303"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="6">
        <location>
            <begin position="375"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="7">
        <location>
            <begin position="375"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="714"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="603"/>
            <end position="669"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="739" mass="80505" checksum="6CBB733A10F275F2" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCB7</accession>
    <name>A0A2H5VCB7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Methyl-accepting chemotaxis protein McpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mcpA</name>
        <name evidence="9" type="ORF">HRbin05_00373</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74335">
        <property type="protein sequence ID" value="GBC74335"/>
        <property type="gene ID" value="HRbin05_00373"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Methyl-accepting transducer" evidence="8">
        <location>
            <begin position="38"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="357" mass="40252" checksum="E1054D63A5778D09" modified="2018-02-28" version="1">MQVGKAVGFTPSRDNGNSKGKGKEATLEEIADLAYRLTDNTVKAIEEIEKINEEIHLLAVNALIEAARAGEAGKTFSVVASYMSELNKKVESITRRIKDEMNMQELSNVIRKQSIIVKGNRLADIALTNIDMVDRSLYERASDVTWWAHDSYVIEVLKNKNRDSIRNVEKRLSIILDAYTVYHDIVVCDIDGNIVASGRNPTLKGKNCKDTEWFKTAFKSRFGFEYPNYSPLADNRLVFIFSSVIRDDSGSTIGVLANIFKWKEFAQRIVENIPLSDKEKRYTRACITNNEGLIFADSAGKIFDTIEFNGRDELFNNAREFIVGEVKGKRCIVAHALSQGYENYSSGLHSLLIQELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCC7</accession>
    <name>A0A2H5VCC7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74345">
        <property type="protein sequence ID" value="GBC74345"/>
        <property type="gene ID" value="HRbin05_00385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009788">
        <property type="entry name" value="GvpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07088">
        <property type="entry name" value="GvpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="43"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="485" mass="54621" checksum="7CF9FC81BA3E707C" modified="2018-02-28" version="1">MLKYYSSDNLGMESSIIRDDVVREGLEYACITESLLDRFLRTKPTSLLIRGPPGSGKTTLALELLKASNRAGYYISTRVSLKKIKEQFPWIADLLKDEYTVNKDYNVNGNDDGSIPVVDARLGSAKGVLERVLDFILMHGDSVIILDSWDAIAKEADKNERLKAEKSMVYMSDANNGLLIFISEEPEENTVSYLVDGVITLDMEYRDGFRMRKMRFDKMRGVEVKHSIVPYTLKGSRFIPLPVGINYSYPEHPRYFERIDAGEGLISTGSKDLDEALYGGIKKGSIILLERDQSVSKVYITHILSSLVLNSLRSGIPTFTTPAPYVPLKSIMKYVRPFCKAEELNLYTVFTKNDEYDESINVCKLTNDARFNVNQTCNLYMNAISKHSCAVLTCDTSLATVHYDLDDVLNGIKKVKASDGILLMISNKDSPLFNAVQSVADIHIKMWEENGVTMLRLVRPYNGVYAMLLESSIKGYPSYRLIEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCC8</accession>
    <name>A0A2H5VCC8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="11">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 12" type="primary">ctaB</name>
        <name evidence="12" type="ORF">HRbin05_00389</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 11">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cell membrane</location>
            <topology evidence="3 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="11"/>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74349">
        <property type="protein sequence ID" value="GBC74349"/>
        <property type="gene ID" value="HRbin05_00389"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 11" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="209"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="234"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="273"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GBC74349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="297" mass="32383" checksum="EC946CFDDEC4FE76" modified="2018-02-28" version="1">MLYNLGLKGYLLISKLRIVAVLNLVAITSLIAAGKGAVGAWDVAFLLLTGSMASMGSSALNHYYDKDIDVLMNRTSKRPIPSGVMKARNALIYGLGMSIASVIIALLTLNAMTAFFIALGIFFYVLIYTVWLKRRHTSNIVIGGFAGSCASYAGWAAATGGIDPLGFLVGFIVFLWTPTHFWCLSIVGREEYANARVPMLPVLVGDKRAAMYILVNTIVLVPYSIVIAFLGLGVVYLIASILAGIMLLHYNIRLVRNTSKDVAWHTYKLSSPYLAIIFIALMLDSIYNYPLPLITLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCD0</accession>
    <name>A0A2H5VCD0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00358</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74320">
        <property type="protein sequence ID" value="GBC74320"/>
        <property type="gene ID" value="HRbin05_00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002798">
        <property type="entry name" value="SpoIIM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01944">
        <property type="entry name" value="SpoIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="174" mass="19039" checksum="7C225FC476C824E3" modified="2018-02-28" version="1">MSKRRRLILLAIASLAFIAFFNIGANSEISEQDAKNMTEQFKEMVKDIDAYGIFLNNFRIALAMFIPALGILIGLFSAYSTGLVFKALVTTTPELAGIPPLLVLATPFGIMEVISYGLAMSQSGILLQNIIQKKGFRIAIVPTLILIGIVCALLLAGAFIEYYMIRSAMDRVQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCD4</accession>
    <name>A0A2H5VCD4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminoacyl-tRNA hydrolase</fullName>
            <ecNumber evidence="1">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74355">
        <property type="protein sequence ID" value="GBC74355"/>
        <property type="gene ID" value="HRbin05_00395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02430">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023476">
        <property type="entry name" value="Pep_tRNA_hydro_II_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002833">
        <property type="entry name" value="PTH2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12649">
        <property type="entry name" value="PTHR12649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01981">
        <property type="entry name" value="PTH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102462">
        <property type="entry name" value="SSF102462"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00283">
        <property type="entry name" value="arch_pth2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013260"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="119" mass="12990" checksum="8206598BC8418A7E" modified="2018-02-28" version="1">MSDMIKQVIVVRRDIHMGIGKLAAQVAHAAVLGAEKVKATRREWFDSWMMHGQAKIVLKVKDKDELMQVKSKAEMLALPVVQVDDAGLTQLEPGTTTCIAIGPAPADMIDKVTGELKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCD8</accession>
    <name>A0A2H5VCD8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00383</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74344">
        <property type="protein sequence ID" value="GBC74344"/>
        <property type="gene ID" value="HRbin05_00383"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="188" mass="20690" checksum="C4613242B92D4FFD" modified="2018-02-28" version="1">MQDIRIQARDKVKILAVGLLAGLNATLVVSGLIFAGEALMNYPHGLFYLIIGYSLGFDGSNALGMGMVMHIVTGVLIGLVASIPVVTVERLFRALSNFNTAMIYGIIVGVLVWLLFFLPVYYLIVMPTLEGYNGVAYDRSGRILTDLNLSFARVIYYSIGLHIQFGIVYSIITGAFIERMMKILSLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCE1</accession>
    <name>A0A2H5VCE1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00397</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74357">
        <property type="protein sequence ID" value="GBC74357"/>
        <property type="gene ID" value="HRbin05_00397"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="312"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="400"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="431"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="3">
        <location>
            <begin position="23"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="457" mass="49725" checksum="69EBA9C9E220AE1E" modified="2018-02-28" version="1">MDRDRGNGKSKKKEREEKGSTMMLLLLYICALSMGIAYGAHVPLVPVFAREVLNATYTEVGMVGMANYIPYAFFPFIVGLLLDRFNKGAMLLSGVSMALASIAMLSLARSILDLALIRAFSGIAHAFFWPSAEAMISMSTRIDESSNSPDRNNSSSGNNDRDKSSNSSSSNSSSNSNSSSGSLGSVRSISRFTMAWVFGYMVGPLIGSSLFHLGYLQLFIYSSTMIIPALACSIIIILLSKHKGYSSDGIKGEEDRRSRSSDSKGRVDLTLINIVKGKIMFIAMIMYYSASFAILLSIVPSYMKDNGVDEQLIGMLFFIFGIARMLTLLSIQLFARYEHISILIASGAIASSMLIMHTAPTPPSFGIALLALGFAFSIYFPITLTMLTRYVPSKMIGSMVGLYETIFGIGWTLGPITSGIVADVFSIDAPYLAMFLIGVVMIPIYTMLRLKDGTITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCE6</accession>
    <name>A0A2H5VCE6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sec-independent protein translocase protein TatA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tatA_1</name>
        <name evidence="8" type="ORF">HRbin05_00406</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74366">
        <property type="protein sequence ID" value="GBC74366"/>
        <property type="gene ID" value="HRbin05_00406"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="102" mass="11210" checksum="DE12BA4786D26A8E" modified="2018-02-28" version="1">MLLFISGAEWIWIIVIVGVLLFGAKKIPELARSLGRATGEYEKARLEAEREIRGYRADGSKMSREKLEAIARTLGIDPSGKDDDELKAEIERAIGSSSSSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCE7</accession>
    <name>A0A2H5VCE7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00409</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74369">
        <property type="protein sequence ID" value="GBC74369"/>
        <property type="gene ID" value="HRbin05_00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="123" mass="14062" checksum="E7011C1973004C3D" modified="2018-02-28" version="1">MQSLHNIEGKNIKEMDALEIALSLKRRPAYVQCYCILKCVSMNSNLKLYQLSRLLGLDYYQVMKRVSELSIKGFLHLKNGTISITDDGIKLKDALESLIMLLHAKDVDEEDVSKRLSLYEILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCF3</accession>
    <name>A0A2H5VCF3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L15e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HRbin05_00412</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74372">
        <property type="protein sequence ID" value="GBC74372"/>
        <property type="gene ID" value="HRbin05_00412"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024794">
        <property type="entry name" value="Rbsml_L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000439">
        <property type="entry name" value="Ribosomal_L15e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020925">
        <property type="entry name" value="Ribosomal_L15e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11847">
        <property type="entry name" value="PTHR11847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00827">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01384">
        <property type="entry name" value="Ribosomal_L15e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01194">
        <property type="entry name" value="RIBOSOMAL_L15E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="154" mass="18322" checksum="7C7E1D17A339C2B9" modified="2018-02-28" version="1">MVVGMYNYIAESWKRLYKEKNDILKQRIVAARREHAIVRVDKPSRLDRARALGYKAKQGFIVVRVRVSKGGMRRKRARAGRRPKHIGVVKIKQAESMKRVAERRVAERYPNMEVRGSYYLFEDGRYYWFECILVDKSHPAVKNDRELKHQLVFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCH4</accession>
    <name>A0A2H5VCH4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster insertion protein ErpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">erpA</name>
        <name evidence="2" type="ORF">HRbin05_00427</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74387">
        <property type="protein sequence ID" value="GBC74387"/>
        <property type="gene ID" value="HRbin05_00427"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="1">
        <location>
            <begin position="9"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="115" mass="12704" checksum="C9EBAC4094DAFD40" modified="2018-02-28" version="1">MEKSIQRLIVLTPKAAEKVKEFMKQEGRDDLYLRVYVAGGGCAGLSYGMGFEEKPSEDDIILEEHGVKILVDSYSSNYLKGSEIDYIESLMGAGFKINNPNVVRSCACGHSFSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCH6</accession>
    <name>A0A2H5VCH6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74395">
        <property type="protein sequence ID" value="GBC74395"/>
        <property type="gene ID" value="HRbin05_00435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="210" mass="23344" checksum="65EC69F9AE164690" modified="2018-02-28" version="1">MAFASKWSKPNEPGMGEKLQSVVKPTGPLKPRIEHAQRKLQMQIMKLDSIAQKLREKDQLLFKRIVQSIQQHDTQYSAVLSNELAQIRKLNKMVNQAKLALEQIQLRLSTITELGDVVVTLSPAMAVVKNVRSGLASMMPEVDNEMGEISELLGGILMDAGQVGGYNINFEYANEEATKILEEAASVVESKMKEKFPDLPSMSEDSKIMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCH8</accession>
    <name>A0A2H5VCH8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Virginiamycin B lyase</fullName>
            <ecNumber evidence="1">4.2.99.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">vgb</name>
        <name evidence="1" type="ORF">HRbin05_00410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.-" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74370">
        <property type="protein sequence ID" value="GBC74370"/>
        <property type="gene ID" value="HRbin05_00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="545" mass="60812" checksum="E1A08205CD4087F5" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCH9</accession>
    <name>A0A2H5VCH9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00443</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74403">
        <property type="protein sequence ID" value="GBC74403"/>
        <property type="gene ID" value="HRbin05_00443"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="151" mass="16279" checksum="E36F60BDCB0F19FF" modified="2018-02-28" version="1">MVIVFESIGILLSLLSKVMLTLTALLLPSLSFLILTISSPSTSSFSLPPSSPPFPLSPSSTIPSSSLALLPLLSCMRDCNLSTLSALTLFSPRTNAIASSMLLLPEPFGPVMHTSPLSRFRIVLFLANDLKPDISTFLIYTMDVYLSCLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCI4</accession>
    <name>A0A2H5VCI4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00318</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74281">
        <property type="protein sequence ID" value="GBC74281"/>
        <property type="gene ID" value="HRbin05_00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="76" mass="9179" checksum="1F3C11D094916328" modified="2018-02-28" version="1">MVSCFFCRKRVWYRRDLSNPFAVNKERTHAYECTNCKVIFLVKNESSKKSRGRREYWQDKTIVKGRVMKILVKDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCI7</accession>
    <name>A0A2H5VCI7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol-3-phosphate synthase</fullName>
            <ecNumber evidence="3">5.5.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ino1</name>
        <name evidence="3" type="ORF">HRbin05_00445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.5.1.4" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74405">
        <property type="protein sequence ID" value="GBC74405"/>
        <property type="gene ID" value="HRbin05_00445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inos-1-P_synth" evidence="2">
        <location>
            <begin position="191"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="356" mass="39342" checksum="62B12A54D7CE4E9F" modified="2018-02-28" version="1">MRKKVRVAIAGVGNCASALIQGTRYYAQAHEDDATGLIAYSLGGIEPGDIEFVAAFDVAENKVGKDLAEGIFEEPNNTLKVCDVERLGVKIEKGEVHDGIGRHLSDIVKVSSEAPVDVAKRLKEVKADVLINYLPVGSVKGTMYYAEQALKAHTCFINAMPVFIASDERWQSRFVEQCLPVAGDDVMSQLGATVLHKTLIKLLVDRGVKVEHTYQLNIGGDADFYNMLDEERLEQKRESKASAVRAMLPYEVPMRIGPSDYVPFLANEKVCYIHIKGRYFCNVPLEINVKLNVIDAFNSAGVMIDAVRAARIALDRGISGPLVSVSAYCFKHPPVQMPYNEAKQAFMEFVQGKRDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCJ6</accession>
    <name>A0A2H5VCJ6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pstC</name>
        <name evidence="11" type="ORF">HRbin05_00459</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74419">
        <property type="protein sequence ID" value="GBC74419"/>
        <property type="gene ID" value="HRbin05_00459"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="90"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="91"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="314" mass="34008" checksum="C1A8E210223B3AC4" modified="2018-02-28" version="1">MGKANEQMKKGDRDSRPLFLGKNSSNLIDVMVKYLLLSAALFTIIAIIIIVYSLASESLSFFLHIPAHEFFFGTRWAAFFDDKSFGVLPLLAGTMLTTAIALSLAIPVGIGSAIFLSEYAAPSLRRVVKPILEMLAGIPTVVYGYFALYFITPNLQYFIPDLYTYNALAAGIAMGIMIIPTIASLSEDAFYAVPQSLKAAGYALGARKSTVVMRIVIPYTLSAIVAIIILGMGRAIGETMIVTIAAGLKPTLTLNPFESVMTMTSAIAQAATGDAPRGTVEYTSLFAIALYLFAIVAILNLISSYIKRRWEIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCJ7</accession>
    <name>A0A2H5VCJ7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">nrgA</name>
        <name evidence="10" type="ORF">HRbin05_00463</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74423">
        <property type="protein sequence ID" value="GBC74423"/>
        <property type="gene ID" value="HRbin05_00463"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018047">
        <property type="entry name" value="Ammonium_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43029">
        <property type="entry name" value="PTHR43029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01219">
        <property type="entry name" value="AMMONIUM_TRANSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="315"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="9">
        <location>
            <begin position="9"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="409" mass="43092" checksum="918364744AC850E1" modified="2018-02-28" version="1">MPIDTGDTAWMILSTAMVFLMIGGVGFLEAGLIRAKNALGILMKVYQTSTIGLIAWFIIGFSLVFAPSEHGWIGTFDYAFMRGVTLEPMSYAPTIPGYLFFLFQGMFAAITVALISGGIAERMRFGPWLVFIFIWMIFVYGPVAHWIWGGGWLAKMGARDWAGGIVIHVAAGFSSLAGALALGRRLGFGKAETMAQHNVPYQFLAAFLLWFGWNGFNGGSALASNEAAVAAIVSTNLAAAAGAITTLLAGWAKSKKPSTSLAANGCIAGLAAVTPAAGFIEAWAGVVIGAVAGVVFYGFVLLFKEKLRVDDACDVIAIHGMTGVWGSMGVALFASPMVTGGALVGVAYGSAELVGVQALAIVVTAAFAFTLTYIIMQIMNKVTPIRLKPQEEEAGEDVVLHGEKAYLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCJ8</accession>
    <name>A0A2H5VCJ8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">phoU</name>
        <name evidence="3" type="ORF">HRbin05_00462</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74422">
        <property type="protein sequence ID" value="GBC74422"/>
        <property type="gene ID" value="HRbin05_00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="16"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="117"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="208" mass="23887" checksum="9E0F52E6A3625116" modified="2018-02-28" version="1">MRRLLDVGINRLSNLLHDMSRLSQECVAMAIDAYLKDRSVVQEVYAKANQLAILKEEVNDLAVELMIRYQPVATDLRFISSCMEVAYDLVRFGRYAYDIAQIREQFGDLGRCDKSIIAEMSEMVSEMLKDSISAFNNKDEDLAERLIRMDDMVDSSYKSNLKKIVETGMDIRCALSSVLVMRYLERIADHAVYIGELVRYMVSGERAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCK5</accession>
    <name>A0A2H5VCK5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative Nudix hydrolase NudL</fullName>
            <ecNumber evidence="2">3.6.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nudL</name>
        <name evidence="2" type="ORF">HRbin05_00457</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74417">
        <property type="protein sequence ID" value="GBC74417"/>
        <property type="gene ID" value="HRbin05_00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="36"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="202" mass="22648" checksum="B4346A121462A64E" modified="2018-02-28" version="1">MQMDIDRITLTRVLESRLHTGYTSRGINSLDDCKGKRRIPAAVLLIIHFTDGYAKIILCKRSERLRNHAGQISLPGGTFKPEDGSLLDTALREAREEIGVDISKDSILGSLDDVDTFSSNFTVKPFVAVLDSISSIKIDGKEVDYIIDAPLVELLSSISRDEEHGYREAYKFIYNGHVVWGATARILKQLRDILEDVIPLHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCK9</accession>
    <name>A0A2H5VCK9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74425">
        <property type="protein sequence ID" value="GBC74425"/>
        <property type="gene ID" value="HRbin05_00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="225" mass="25702" checksum="3762828FC1739DBA" modified="2018-02-28" version="1">MKRIEAIVRTEIMPDLKIQLERFEIYGLSMHNITSTNITSRNGAVGRGGGLGEFLTKVELIVSDRDAKRVIDTISAVSGKHKEYTKIFVSSLEEIVDVSHMHVIKDLEDVNDSEDRTRKQDSSIASSGVDEEHGNYSNEDSTDRIDASSGEYEEQEKRSRLVPLQKYTLMRVLKFYNANKDTLRSEYRIKSFSDFVNFCILGYLPIIESEIKQQSIEGRSKLLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCM1</accession>
    <name>A0A2H5VCM1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74446">
        <property type="protein sequence ID" value="GBC74446"/>
        <property type="gene ID" value="HRbin05_00486"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="2">
        <location>
            <begin position="9"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="391" mass="41960" checksum="4C9645A86562409A" modified="2018-02-28" version="1">MHASGNKALRVILLLGLVSLAADMVYEGARSIIGPYLLILGASATLVGLVAGIGEIASYGSRILFGYAADKSRKHWTLIITGYAMILSLPALTFANRLDVASTLIILERLGKAIRTPSRDVIIAHTASSIGRGKGFGIHEAMDQIGAVIGPLIVAVVMNYKGYNDAFLYLFIPATATLPLLMYARRHAVLLDSDAYTNIHTRASIGSIPRLLWLYLAFVSISVAGFAHFQIISYHIKFTSAMDDVYIPILFALAMGVDALIAIIVGHIFDRKGLLVLILVPLTTLPIAPLAFSTNPTFIVAGAVLWGIVMGMQETIMRASIATMVDRARLATAYGLFNGIYGIAWFSGSIMMGMLYESSVLGVITFSVTLSIASMLLLLVMLKVLEASSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCM9</accession>
    <name>A0A2H5VCM9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00493</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74452">
        <property type="protein sequence ID" value="GBC74452"/>
        <property type="gene ID" value="HRbin05_00493"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="167" mass="19358" checksum="D62A0826E839D069" modified="2018-02-28" version="1">MLGFGKKQVKEGDYVFATIDEGSYSKVVLGYVNFAEMDKIKVTGIYIKPIGLLDRVRSGRITQRQQEVLRSPTPDNIIHIIIDRVEYGIFDDYLKPNSAIVRISAKRYSEIETWVRDGYPELFSILLSPIDPRREEARQIFMEKYNSIYDSEFKQTVSAVARQLRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCN2</accession>
    <name>A0A2H5VCN2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mrr_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00488</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74448">
        <property type="protein sequence ID" value="GBC74448"/>
        <property type="gene ID" value="HRbin05_00488"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mrr_cat" evidence="1">
        <location>
            <begin position="138"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="284" mass="32534" checksum="7291811FC1BEA45F" modified="2018-02-28" version="1">MLWSFVHDISLGDIILSPKKETRKLLIGIVTGPYLYDPKAIDRDYPNIHAVEWKGVIPYDNVPREIWRSMTAWQTLFELSSPEAVNAALRLMESIQTGVTPRPIETPERTAVAMDEGQRLFDETMSKSMEILATHFDGFSGWEFQELVWATLKAAGLYPKPLRKGPDQTVDIEAYRDPLQLGPPRILVQVKHRRDPVSGPEMQQFIGSMNREGDIGLYISTGGFSQAARQFAEKSHKPVNLMGWEDFVNLFLEVYERLDNTFKAWIPMGTVKILLRRKEEVQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCN5</accession>
    <name>A0A2H5VCN5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-glutamate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">cheR</name>
        <name evidence="7" type="ORF">HRbin05_00369</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="2.1.1.80"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.80" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74331">
        <property type="protein sequence ID" value="GBC74331"/>
        <property type="gene ID" value="HRbin05_00369"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008983">
        <property type="term" value="F:protein-glutamate O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.155.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036804">
        <property type="entry name" value="CheR_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheR-type methyltransferase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="253" mass="29423" checksum="A062A2C1BB81794C" modified="2018-02-28" version="1">MLVIDEHYYNRLRDIIRVRVGIDISCYSKSFIARRVEFRMNIYNIKDYNDYLRLLESSDEVNAFVANLSINVTEFFRDPDVFDRFKELLKGYSSARIWSVGCASGEEPYTIAIIAKDNGVRCSILASDINKNAIEYAKKGLYPSKSIRNVPKDILAKYFTLTGDRYAVRNDVKDMVTFEVRDITKSIYTGQFDFIFCRNMLIYMDHVSKERIINNICNAMKPHSYLILGKSEYVHNCSMLSCIDTKAKIYMKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCN9</accession>
    <name>A0A2H5VCN9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplK</name>
        <name evidence="4" type="synonym">rpl11</name>
        <name evidence="8" type="ORF">HRbin05_00500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74459">
        <property type="protein sequence ID" value="GBC74459"/>
        <property type="gene ID" value="HRbin05_00500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="7">
        <location>
            <begin position="7"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="6">
        <location>
            <begin position="71"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="159" mass="16587" checksum="CB9792FD82AB8EBF" modified="2018-02-28" version="1">MGEKKIISLLVTGGEANAGPPLGPSLGPLGVNVLAVVNAINEKTREYAGMKVPVKVEVDVESKEFTIDVGIPPTAMLIMKEAGISKGSGKPGQEYVGDITMDKVLKIARLKINSSYARSLMAAVKEVIGACGSLGVTVDGKKPKEVLKAIDDGKVKIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCP7</accession>
    <name>A0A2H5VCP7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74454">
        <property type="protein sequence ID" value="GBC74454"/>
        <property type="gene ID" value="HRbin05_00495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="136" mass="16412" checksum="4999D99739FEBB19" modified="2018-02-28" version="1">MWRLNVRRMYLNNVFDVGKFFVNRRFNIQHGELLLLQLVKKDDPRHLGRIRGIMESDGVVEDEHDESVELYGRKWKYAILASRSIRLQPRDWFDLDDIIGINARKYYTQVEAMRLEHDDALAVERRLARYLKHIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCR6</accession>
    <name>A0A2H5VCR6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">argS</name>
        <name evidence="6" type="ORF">HRbin05_00534</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000022">
        <property type="protein sequence ID" value="GBC74493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74493">
        <property type="protein sequence ID" value="GBC74493"/>
        <property type="gene ID" value="HRbin05_00534"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DALR_1" evidence="5">
        <location>
            <begin position="235"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="261"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="374" mass="41825" checksum="2A1F5921551BA990" modified="2018-02-28" version="1">MQSKDILKVDDDPASKYHGCIVVKAGIEGEEKVLVRSDGTATYIAKDIPYAMWKLGIVEDPFKYVEYAKQPDGSMLWATSLYSNGSLLKLNGADIAITVIDVRQSRLQKIIAKILSMLDKDSSRYKHLAYEVVALSASTARLFNIDIGDRRFAHMKGREGIYINADDMLDRLHNKAYEEVKARNPDGDEQWLHSTAESIAVAALRYSMLKQDLDKIITFDIEDALNLQGESGQYIQYAYARASRILEKASRIAAVVVGEGRGGEEGEEEGGRRGGIDIDPSSTHLIGNGEVALIKTIARFDLVVEDTVKSLNPKTIARYCYTLAMVFNEFYEKVPVLHEKDTDLIRMRLSIVKAFTTTMSNCMYLLGIDALERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCS1</accession>
    <name>A0A2H5VCS1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfurtransferase TusA</fullName>
            <ecNumber evidence="2">2.8.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tusA</name>
        <name evidence="2" type="ORF">HRbin05_00537</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.-" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74496">
        <property type="protein sequence ID" value="GBC74496"/>
        <property type="gene ID" value="HRbin05_00537"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01148">
        <property type="entry name" value="UPF0033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="UPF0033" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="80" mass="9118" checksum="E321983FD3D7AF7A" modified="2018-02-28" version="1">MSSEVSQDVKTIDVRGLFCPEPVFRTKIAMERLSVGSMLRVIADDPDAEEDIKRWVQRTGHELISLSKEGSNLIFLIRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCV0</accession>
    <name>A0A2H5VCV0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Putative cation efflux system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HRbin05_00564</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000025">
        <property type="protein sequence ID" value="GBC74522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74522">
        <property type="protein sequence ID" value="GBC74522"/>
        <property type="gene ID" value="HRbin05_00564"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="8">
        <location>
            <begin position="209"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="8">
        <location>
            <begin position="348"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="8">
        <location>
            <begin position="409"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="318"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="495" mass="54492" checksum="941BC6AFF6C3C5AB" modified="2018-02-28" version="1">MLKPVKRMEQKSALSLSLIAIASVALFEIIAGIASNSMAVLSDGIHASFDALLTAILLIMLSMSMKPRDMEHTYGHGRLETLAGLIGGIALFIVAIFIVRESLFRIVGAEGIVPSMLAFYAVTVAICVATLRALVLAYSMHGMSTRVGFYDAVADLGSSVLALIGFILASNGLYAADGLASIALAGMIIFLTSRLVYSSAMELTDAIDPSLVEKARRAILSIDGVKYCKDIRMRKVGRDVLADVTVVLEGSITFSRAHAISSEVEHAVMRVAKASRVMVHFEPEYEHMPIEHIIADIASGVNGVKDVHNVVVSRERVRKKNVNGSEDKAKDKDGSYNDNDNGDAIEALIVSMHVQVDRNLRLDEAHKVADMVEYEVKRRVKGIRDVMVHIEPIMPKMDMVEELRDGVLEARIRSIASEQGVRQISRIGVYRCNDMLTRIDMHCSIDADTSIEEAHEIISRLERRIRDELNAIAMIHVEPYGYDNTSRSMQINRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCV3</accession>
    <name>A0A2H5VCV3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00559</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000025">
        <property type="protein sequence ID" value="GBC74517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74517">
        <property type="protein sequence ID" value="GBC74517"/>
        <property type="gene ID" value="HRbin05_00559"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="137" mass="15074" checksum="F018801ECF6BDACC" modified="2018-02-28" version="1">MIKIFIHKDFTLPMLGKDSFVKLMRAGVEYDKTSRRFRIKEGADVASILAILNEVVREEISIELPCIVCGNDAGCSECEFSSNCDRTSVSSKCICKQCIEGGYHGYTEHLSSLFNAAKSRGDGEQGRGRGRRGGEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCV7</accession>
    <name>A0A2H5VCV7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps15</name>
        <name evidence="6" type="ORF">HRbin05_00567</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74525">
        <property type="protein sequence ID" value="GBC74525"/>
        <property type="gene ID" value="HRbin05_00567"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_A">
        <property type="entry name" value="Ribosomal_S15_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012606">
        <property type="entry name" value="Ribosomal_S13/S15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023029">
        <property type="entry name" value="Ribosomal_S15P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11885">
        <property type="entry name" value="PTHR11885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08069">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01386">
        <property type="entry name" value="Ribosomal_S13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S13_N" evidence="5">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="148" mass="17039" checksum="F273905D282F6A82" modified="2018-02-28" version="1">MARIHAHRKGKSHSIRPMQVNAPWISNMSKEEITNLIVSMAKDGLKPSEIGLRLRDEYGIPLVKKIIGKSITEVLEDHGIKTLPEDLSNMLEKAIRLQKHLNVHRSDSNNIRSLELIEAKIHRLAKYYKREGKIPQDWKYKTVIASLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCW3</accession>
    <name>A0A2H5VCW3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-amino-4-hydroxybenzoic acid synthase</fullName>
            <ecNumber evidence="3">4.1.99.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">griH</name>
        <name evidence="3" type="ORF">HRbin05_00541</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.20" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74500">
        <property type="protein sequence ID" value="GBC74500"/>
        <property type="gene ID" value="HRbin05_00541"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002812">
        <property type="entry name" value="DHQ_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33563">
        <property type="entry name" value="PTHR33563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01959">
        <property type="entry name" value="DHQS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006655">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="363" mass="40050" checksum="E4810766A2007137" modified="2018-02-28" version="1">MLDKIGKGYKSLIVKPLGSNIESFLSQLRDEGIRYIYIDPSLLSSSSLDYFVTVYESDDADMKVCSSIDELIKAKSNGKSAGLLVNVKSKRDEDTIVDAAKHDADFVLVDADDWKIIPLENIIAKLQGMKSMILAYARDANEVRTLLNVLQVGVDGVVLEASDIASVRQSLVYMQSKEFKLVYAVVKDVRDSGVGERACIDTASMLKVGEGMLIGSRANFLFLMHNEAIGSEFTSPRPFRVNAGAVHCYTLMPDGRTKYLSEIEAGDEVLIVNMDGKARNAIVGRVKIETRPMRLVKAEVDVDGVKEEGSIIVQNAETIRFIGRDNRLIAVTDLKVGDEVLVYAKGSRGRHFGIEVDEFILEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCX2</accession>
    <name>A0A2H5VCX2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amicyanin-alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mauC_2</name>
        <name evidence="4" type="ORF">HRbin05_00552</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000024">
        <property type="protein sequence ID" value="GBC74510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74510">
        <property type="protein sequence ID" value="GBC74510"/>
        <property type="gene ID" value="HRbin05_00552"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028096">
        <property type="entry name" value="EfeO_Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13473">
        <property type="entry name" value="Cupredoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Cupredoxin_1" evidence="3">
        <location>
            <begin position="181"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="147"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="287" mass="30002" checksum="960BB612D1AB1BE4" modified="2018-02-28" version="1">MVPGLGLAVIGMLGVILSLAGIARTFVEGMHAISAIAMVFGMILLAAGILKDGLPRSKEAKAATIFIAGILAALGGLLAGLSTVSTLPILIGTLLLIFVPATAIAYAVHKGSRHVKAIAAIFIGGSLMGFITFSIFSIMQQPTQAIEEQGEQARPGAEAGTETGTQVEQPKQEPAPTGPVVEITILLDSSIQGNPDFDPDEVSVERGTVVVWKNTDTAVHTVASGKGFDDPNFAKFFNSPVINVNSTWSLDTSALEPGEYDYFCTIHAYMQGKLIVVEKETGETGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCX5</accession>
    <name>A0A2H5VCX5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00576</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74534">
        <property type="protein sequence ID" value="GBC74534"/>
        <property type="gene ID" value="HRbin05_00576"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="137" mass="15395" checksum="67ECB70FD8472C44" modified="2018-02-28" version="1">MINVKSNSIDYNVMLLYLIVGAGVMGTAMLTAFLMLMPYSNQDYALDVDAFKDKIDVMDIYRVIITNTGRNDVTNVVVDYGTYKDFIPRIKPGEKISLSPRDDANKEYVVITAEPSIHIMKEYRSMPKAPGMIGGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCY8</accession>
    <name>A0A2H5VCY8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Prefoldin subunit beta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">GimC subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pfdB</name>
        <name evidence="9" type="ORF">HRbin05_00599</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 7">Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 7">Heterohexamer of two alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the prefoldin subunit beta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74557">
        <property type="protein sequence ID" value="GBC74557"/>
        <property type="gene ID" value="HRbin05_00599"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016272">
        <property type="term" value="C:prefoldin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00307">
        <property type="entry name" value="PfdB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002777">
        <property type="entry name" value="PFD_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012713">
        <property type="entry name" value="PfdB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009053">
        <property type="entry name" value="Prefoldin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01920">
        <property type="entry name" value="Prefoldin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02338">
        <property type="entry name" value="gimC_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="10"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="123" mass="14126" checksum="2185FA76C8636DCB" modified="2018-02-28" version="1">MSEQELPPWLREQLARLNQLQQNLQAILMQKQQLEIESVEIDKAIEELKKAGVDDAVYKSAGPVLIKGKRDDVLKELEEKKELLSTRIMVLSKQESRLKENLKDVQSRIDEMIRGQSTGARAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCZ1</accession>
    <name>A0A2H5VCZ1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA integrity scanning protein DisA</fullName>
            <ecNumber evidence="2">2.7.7.85</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">disA</name>
        <name evidence="2" type="ORF">HRbin05_00597</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.85" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74555">
        <property type="protein sequence ID" value="GBC74555"/>
        <property type="gene ID" value="HRbin05_00597"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006259">
        <property type="term" value="P:DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ERCC4" evidence="1">
        <location>
            <begin position="10"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="244" mass="27264" checksum="2A06CC11C0DCA66F" modified="2018-02-28" version="1">MSSNKKARLRIVVDEREKRSMVPDALKELGANVEYAVLDVGDYLVYGNCCIERKSVDDLINSIYDARLFIQVDEMLKHYSRSVVIVEGSSEDIEGMDKPNVLYSALASLAVEYRVPVVYTPSYLHTALAIVALAKHCSSKEDAYREPLLKRIRKSKDGLLREQQLSIIASLPGIGSRLASRLLERFGSPINIFNASTADLARVEGIGYAKARKIRYALDTSISSKFTRHNLLDDYTDATDVRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCZ7</accession>
    <name>A0A2H5VCZ7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00606</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000029">
        <property type="protein sequence ID" value="GBC74564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74564">
        <property type="protein sequence ID" value="GBC74564"/>
        <property type="gene ID" value="HRbin05_00606"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="138" mass="16217" checksum="9DCEF530DD71F97C" modified="2018-02-28" version="1">MLREDKDGRYKHINNNSSSKDESSIKSKGKSREKGKYASSTENRRLVWNNIVWPLILELNKPWFTIEEYHAKRDAFCSSYGDEMKSKVAGGFVSLIVKGLLLKDKDREVYSIHWKLVPYMRKRLWLDYGEAIRLISTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD03</accession>
    <name>A0A2H5VD03_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferredoxin-2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00592</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74550">
        <property type="protein sequence ID" value="GBC74550"/>
        <property type="gene ID" value="HRbin05_00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="271"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="2">
        <location>
            <begin position="310"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="339" mass="37388" checksum="CF533AA9660E8F2B" modified="2018-02-28" version="1">MSSLLEDKVYAVLSETTKRGVYPLHGYKYGLYRIPVDLTSKEDIQSVVSSLSSIFKVDVYADRIYVTYRWKEQDVTPVKPEEWKEVELEVTVEIVTGEVIDIIYQVKPLDYFPDAYWVKNYRVKADNNAKMVIDTILRSTIIGEKLVKDWVKRYKMDEQTARRRLEGLTPLARSMEVAPLAVQQTVQQVAAQQVQQQQQAATATAATTQVQAKPTAKPAASTAAGAGAGGAHAGKGIDPNFTKNRQVAGEHAGHAVWGPVNPPQLLGIHGTYVAVDFDICVADGACIEACPVNVYEWFETPGHPASEKKADPAREADCIFCLACETVCPPMAIKITKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD10</accession>
    <name>A0A2H5VD10_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000031">
        <property type="protein sequence ID" value="GBC74585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74585">
        <property type="protein sequence ID" value="GBC74585"/>
        <property type="gene ID" value="HRbin05_00629"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="70" mass="8236" checksum="5685E3495F8FC6E9" modified="2018-02-28" version="1">MFVQIADGVINKGFKYYNPVNYSMCHIVRCEVCGALMEYEDYYIHSRVCRPETEKVEPVEVKSLAKKRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD13</accession>
    <name>A0A2H5VD13_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">NH(3)-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="4 6">6.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">nadE</name>
        <name evidence="8" type="ORF">HRbin05_00626</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>ATP + deamido-NAD(+) + NH4(+) = AMP + diphosphate + H(+) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21188"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.5" evidence="4 6"/>
    <dbReference type="EMBL" id="BEHH01000031">
        <property type="protein sequence ID" value="GBC74583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74583">
        <property type="protein sequence ID" value="GBC74583"/>
        <property type="gene ID" value="HRbin05_00626"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00193">
        <property type="entry name" value="NadE_ammonia_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022926">
        <property type="entry name" value="NH(3)-dep_NAD(+)_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_synthase" evidence="7">
        <location>
            <begin position="21"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="275"/>
            <end position="276"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="286" mass="31231" checksum="AB3EB58664531946" modified="2018-02-28" version="1">MAVDDMVKKITSSLDYGYVSSKIEHFLLESLEGSGKAGYVLGLSGGLDSSVVAVLAARALYGRGKGKGSLTALIIPHSSITPSSDVNDAIRLAESINIAYRVIDIGDIHSSLAERLHTIDGGGENYSSVDNIKSRIASGNLLARLRMCTLYYYANANDCLVLGTSDRSELMIGYYTKYGDGAADILPIADLYKVQVRALASYLQVDDAIIRKKSGPMLWKGHYAEQELGMSYEEIDSILYCLIDLKSSVKDTASMLGIEEERVKSVIRLVRSSRHKRAPPRICHIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD15</accession>
    <name>A0A2H5VD15_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <ecNumber evidence="2">2.8.4.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rimO</name>
        <name evidence="2" type="ORF">HRbin05_00619</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74577">
        <property type="protein sequence ID" value="GBC74577"/>
        <property type="gene ID" value="HRbin05_00619"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="213"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="503" mass="57108" checksum="33AC2BE13EC2971E" modified="2018-02-28" version="1">MKGKRIVLSADRTLMSHYRDNMLFGFIATFPAEKIPPFIYKSIFCPSVEFNKATGEAMVAPLGLRRVEGGLLKEYGRDEVFIAHPDHIEKAIGEGTEIVGLNVMDPRGIGPVPSALTQGKMTPINRISFRNLCYRLKNLREMKGYRFKVVVGGSGAWQFSFSSKEREDYGIDHVVIGEVDDKIGDICKDIVEGRAREVIFTRTNTIMDIPYIPGPTTNGCIEAMRGCGRGCDFCDPNLRMKRDFPVERLKEEASINLRYGITSIWLQSEEILLYGLDNSEMRPNRDAIVHLFSELKSLPNVNYVAAIHLTFSSAMADPECIAKIREINNFNASRWTGVQIGLETASPALIRRHMPYKVKPFTPEEWPWLVREGIKLLNENYFFVANTLIIGLPGEQDDDVKETIELVKELDGMATVVAPMFYTDYHDPSRSLQGERMSRAQWELYFRCWHLNAKTVARWMAYGTLHFSPVARMVANAFGKLGTWYVLRLIRDGAKKYAGVYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD17</accession>
    <name>A0A2H5VD17_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ferredoxin--NADP(+) reductase</fullName>
            <ecNumber evidence="4">1.18.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fpr</name>
        <name evidence="8" type="ORF">HRbin05_00620</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ferredoxin--NADP reductase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74578">
        <property type="protein sequence ID" value="GBC74578"/>
        <property type="gene ID" value="HRbin05_00620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06195">
        <property type="entry name" value="FNR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033892">
        <property type="entry name" value="FNR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="7">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="282" mass="32420" checksum="6DCC4FD10E028A37" modified="2018-02-28" version="1">MTDNKGVISFIRLYTEDLGIFRIKPVEGQVPDFRAGQFVTLGLPVKSEGGKIVRRAYSIASPPEQKKYFELYIRWVRKPVPGRFTTELFERKEGDEILWLKPTGPFGLVDRWPDGRKEERRIVMIAGGTGLAPFISMTLHLKALRDKREIVVLHGASYVTELGYKELLTQLEEESIDGKDSSWRFRYRASISRPDEFLNRSWGGHKGRVETFLKNDPSTGKSPLEELVGEKITPENTMFYVCGWQGTVDGVLQYLKPLGFIEEKERNKRADKTFDVRYESYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD23</accession>
    <name>A0A2H5VD23_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acryloyl-CoA reductase electron transfer subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">acrA</name>
        <name evidence="4" type="ORF">HRbin05_00637</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000032">
        <property type="protein sequence ID" value="GBC74593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74593">
        <property type="protein sequence ID" value="GBC74593"/>
        <property type="gene ID" value="HRbin05_00637"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="3">
        <location>
            <begin position="8"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="ETF_alpha" evidence="2">
        <location>
            <begin position="260"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="401" mass="45364" checksum="858554883D8C811A" modified="2018-02-28" version="1">MRYQHMFVLFEHDDGNVLNVSYEMLGEARRLMDDFNRRYALNEKVIAILLGHNVRELAYRAIDAGADAVILADHEELRYPRVNLYTKVICSIVRDRMLVKQAEPSTSDEYVKPRYMLFGADSIGRHISATVLAELESGLASDVNKLVIDDVMITHQYKTNGKPELYRQVLFMYRPDFSGFLWTQILCLDNKNPTIAREYSPQACSVIPGVFEPLQQHDGDARKRVEEGYARIVEYKPEFSNDDLKYRIVSRQIVRDEIGLEDSRVVVAFGRGIKDDPEGNIRMIEEFANLLGAKVAISLPLSKQPFNVSSTLKEKYFIPARVVGSSGKKVAPKLYIAIGISGAMHHLAGMKESDTVIAINPDPDAPIKDESDIFIQGRLEDVLPILIESIRGSEEEGRRGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD28</accession>
    <name>A0A2H5VD28_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <ecNumber evidence="2">5.4.99.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">purE</name>
        <name evidence="2" type="ORF">HRbin05_00639</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000032">
        <property type="protein sequence ID" value="GBC74595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74595">
        <property type="protein sequence ID" value="GBC74595"/>
        <property type="gene ID" value="HRbin05_00639"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039476">
        <property type="entry name" value="P2CMN_synthase_LarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43064">
        <property type="entry name" value="PTHR43064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="1">
        <location>
            <begin position="140"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="300" mass="32114" checksum="057CE1D96D5C00D6" modified="2018-02-28" version="1">MSIRDILNAVRDGKISVDDAERMLQLHKIEYVEDIARLDVSRELRRGVPEIVYAEGKEYDDIIRIVLAALKSKDKVIISRIRQEYFDILVEELSKHAEVKASKRGRIVVAIATTTATTMKEGSISNNRGNNDYYYYYRSGTVGIITAGTSDIGVAEEARLVAEAMGCRVIAGYDTGVAGLHRLFLLLKDMLANDVDAIVVVAGMEGALPSVVASLVDVPVIGVPTSVGYGFGAGGVAALTSMLQSCALGLAVVNIDNGVGAGVLAAMIARRVGRYRAGFIKKADESISIEMDGEKAKASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD33</accession>
    <name>A0A2H5VD33_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00647</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74603">
        <property type="protein sequence ID" value="GBC74603"/>
        <property type="gene ID" value="HRbin05_00647"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="182" mass="19133" checksum="18A6AAEACC3DA111" modified="2018-02-28" version="1">MDRKKGSSVIGVIAVLGVAAMLFNMPFQQVHAQTYGVSYQVNPAPIPAPGGTTTITLTITLPPGASVQLLYLNVYEPDGDVCTILSPLSGTGPTTLTLTKVYPTDAALTWNVANDGCDTNEAPGSTWLVYGAIVTSFGTRYFEDNIVLPFMVVPESIIGAVAVTGAGITTFAGYKVLRSKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD43</accession>
    <name>A0A2H5VD43_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00657</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74613">
        <property type="protein sequence ID" value="GBC74613"/>
        <property type="gene ID" value="HRbin05_00657"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018686">
        <property type="entry name" value="DUF2175"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09943">
        <property type="entry name" value="DUF2175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="104" mass="11972" checksum="B7B218778D30CA2B" modified="2018-02-28" version="1">MSTKWSCAICSRQIAWSELFTFYSKGAVHFTCFKETTISKDKSDEVKVLLDALEHELKMIVAYKGYITMVKNDDAKRLLEENEKDAEKHAALLTKLIDRHVMQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD46</accession>
    <name>A0A2H5VD46_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74616">
        <property type="protein sequence ID" value="GBC74616"/>
        <property type="gene ID" value="HRbin05_00660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002809">
        <property type="entry name" value="EMC3/TMCO1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038978">
        <property type="entry name" value="MJ0935"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42198">
        <property type="entry name" value="PTHR42198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01956">
        <property type="entry name" value="EMC3_TMCO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01415">
        <property type="entry name" value="DUF106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="300" mass="34072" checksum="A867B75CD64CA815" modified="2018-02-28" version="1">MSWQTYLLIGGLDDNMVGLIDAISAYLLLPLLLHPLSSSLSLSSLPSILPLQFAPQASAHPYITNMLSASILVSIIAIALQFFYALLRLKMTDMQKLRRMMKEVNDWRREYMDAIRKQDKDRIEKLRGKQEYINRLNMEVMQMNFRPMMVFMIPMLIIWWAVLPQVFGHTVAISPISLNIVGDLLPITCTKGMIVKDVNSITEEISKHAEAIQNPVIRDQVTSLAKEARELVDAGQYVTARDRILTAYSILNANLENKVQERVPSCIAENEVLLWAWYAIASIAFSGIVMKITRTEMSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD51</accession>
    <name>A0A2H5VD51_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00667</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000035">
        <property type="protein sequence ID" value="GBC74623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74623">
        <property type="protein sequence ID" value="GBC74623"/>
        <property type="gene ID" value="HRbin05_00667"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="262" mass="29197" checksum="D007015C5E7AB61F" modified="2018-02-28" version="1">MLALQTSGFIYIAALSISHSIFNNRGRVDNGAGGRVRDESSINIKVDYSYVGRIEKGREGGKDKSNGKGRDKEREIEAGVGYSMKHYKLVLGGILALLMFGVVMAYIGYASSVYPLEKARGYIAVAVTSNSPTTMLEYVLEIEQLVPENGNPVWVFPTPKTDFGMMHKSLDEIKERLRVITTLPRDSEAFNTGMSDVRGQLAQLEDNIREAVPYVYVSFQNVVLSAIWITVILAIFTLMKRGKARIERFEDVESERVGNNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD59</accession>
    <name>A0A2H5VD59_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">secY</name>
        <name evidence="14" type="ORF">HRbin05_00662</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 10">Membrane</location>
            <topology evidence="1 10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74618">
        <property type="protein sequence ID" value="GBC74618"/>
        <property type="gene ID" value="HRbin05_00662"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019561">
        <property type="entry name" value="Translocon_Sec61/SecY_plug_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10559">
        <property type="entry name" value="Plug_translocon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 10" id="KW-0653">Protein transport</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 10 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="36"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="118"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="277"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="432"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="domain" description="Plug_translocon" evidence="13">
        <location>
            <begin position="44"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GBC74618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="474" mass="51941" checksum="AD96AB2B39BE9244" modified="2018-02-28" version="1">MLKPADISFRSIIDKAAVYLPQIPKPKKKLTLTQKFVWSGLVLLVYLVMGQIPLYGAPTSPFDPFAAFRVIFASQQGTLVELGIGPIVTAGLLMQLLKGAEIFKLDFKNPEDRALFTSATKLVTIIVIIVEGAIYGSMVYKMPQDVTMIIIGQLIGASLIVMFLDEMVQKGWGLGSGISLFIMAGVAQSVLWHMFSPVTAQDGLPFGVFPMLIQMASNGNFDIMHALFRFGRLPNIIGLVVTIAIIALLLFTQGMKIEIPIVSSRFRGFTASYPIKFMYVSNVPVILASALIANLVFMAQLFWANYNPLNSREEFNWIAMFDPNNPTTPIGGIVKFLIPTRGIETAMSEPLHAIAYVLILTGIVVLFGRLWIELGGLSPKAAASSLIDADVQVPGFRRVESSIEMLLKRYIPSVTLMSSLFLGFLAGGSDVLGAFGTGTGLLLMVDILINYYNLLLREQIDVYMPRLSALLGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD64</accession>
    <name>A0A2H5VD64_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00681</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000036">
        <property type="protein sequence ID" value="GBC74637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74637">
        <property type="protein sequence ID" value="GBC74637"/>
        <property type="gene ID" value="HRbin05_00681"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902555">
        <property type="term" value="C:endoribonuclease complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038085">
        <property type="entry name" value="Rnp2-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="53"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="161" mass="18059" checksum="C7342552890E03B6" modified="2018-02-28" version="1">MRYKKRYILAYVDAHNPYGYQRKMLKMIRDAYAEIFGSKEVDEARITFVSYGSRRRNGSSSSSSSRDGNAADEMGKIHGAKIGEEVGKADVSRGYIHAHRTMLPLIIRCNLEHYGNVMHILSILGIRTVTTSGTLKALRRRQGLIGEERKIDGDEVRAAPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD67</accession>
    <name>A0A2H5VD67_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00679</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000036">
        <property type="protein sequence ID" value="GBC74635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74635">
        <property type="protein sequence ID" value="GBC74635"/>
        <property type="gene ID" value="HRbin05_00679"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD_M" evidence="2">
        <location>
            <begin position="139"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="1">
        <location>
            <begin position="258"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="481" mass="52990" checksum="85CCF6B52BFFCB9C" modified="2018-02-28" version="1">MYIPTNDLLIKHLGKAKMVKYLDIKVCHNKCNSLIFKGDAIAAREDEDIVITARAVANGYGIASVSKIESTPSSSLEHSIDDIVEQAIEHATSSLSYSQADGSSGSSISNGSNRRGGYGVNLVEVDVERGYATTPVADYDSTSLYELIDYVVSTLRSRLRGRDDVRIEVSLSYVESENGLVSSEGTDIRERTATTTIDIRLTMRYHGGIIQVSKSMGGRGGIEVLKRKSMDDALDEMIATMNHLVHAKQFSILESGIRFKVVLDNEAGGALARLIGNMLEADEFNPKIFSSLYVQEGVEVVDDPTLPNGYGSFVWDDEGVRGRRKVLIGSDTLNLLHTRLTACIPEDGYSTPGNARGVDGIPKPSVSNVYIKPMDWYVDEMVDDARECILMKGVERVSADTRRGIVEIKPMIAYHVKDNEMMYAMKGISLQDSIRNILKGIDAISRVAILKPYRDERYGFRIGEGSPYIRLESARCVCSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD75</accession>
    <name>A0A2H5VD75_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate--CoA ligase [ADP-forming] subunit alpha</fullName>
            <ecNumber evidence="2">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="2">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">sucD</name>
        <name evidence="5" type="ORF">HRbin05_00689</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000037">
        <property type="protein sequence ID" value="GBC74645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74645">
        <property type="protein sequence ID" value="GBC74645"/>
        <property type="gene ID" value="HRbin05_00689"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043758">
        <property type="term" value="F:acetate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="4">
        <location>
            <begin position="31"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="43"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2 3">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="317" mass="34062" checksum="89E164E1220D200B" modified="2018-02-28" version="1">MGMGSSGSVGVEAKQILDIFKILQGNPGDEDYNRKPVIVQGMTGKFGSLHTRLMREYGTNIVAGVTPGKGGQQFDGIPVYDSVRDAVKEHNAEISVVFVPAQFFLNAAVDALTNGIRLMVAIPEHVPVRDTLKCIKLAKENNAVVVGPNTPGIIVPGVIKLGIMPAQPFSKGRTVVISRSGTLMYEISHRLTLAGFGQRLCLGIGGDPINCLTLIECFELIRDRDDVDSVVVVGEIGGSAEEQLAEYIISTEFKKPVVAYIAGRSAPKEKRMGHAGAIVYGTYGSAESKVNMFAKADVPVAKRPAEVPILLEKKMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD76</accession>
    <name>A0A2H5VD76_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosomal_L40e domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00690</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000037">
        <property type="protein sequence ID" value="GBC74646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74646">
        <property type="protein sequence ID" value="GBC74646"/>
        <property type="gene ID" value="HRbin05_00690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038587">
        <property type="entry name" value="L40e_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001975">
        <property type="entry name" value="Ribosomal_L40e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023657">
        <property type="entry name" value="Ribosomal_L40e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39649">
        <property type="entry name" value="PTHR39649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01377">
        <property type="entry name" value="Ribosomal_L40e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L40e" evidence="3">
        <location>
            <begin position="3"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="55" mass="6538" checksum="7DE85EF2E007EBBA" modified="2018-02-28" version="1">MPITDTFKKQIAQRRRLFFKICFKCGAKNHIDAQRCRKCRGDQLRLKNRTLGAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD95</accession>
    <name>A0A2H5VD95_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YcaO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000040">
        <property type="protein sequence ID" value="GBC74665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74665">
        <property type="protein sequence ID" value="GBC74665"/>
        <property type="gene ID" value="HRbin05_00710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003776">
        <property type="entry name" value="YcaO-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02624">
        <property type="entry name" value="YcaO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00702">
        <property type="entry name" value="TIGR00702"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51664">
        <property type="entry name" value="YCAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YcaO" evidence="1">
        <location>
            <begin position="68"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="446" mass="50555" checksum="0E71A4D88DB96288" modified="2018-02-28" version="1">MFELRSQKYVDNMPKVMHVKETLKKALPIARSIGVTRLADITHLDLLRIPNYSAVLPGTDDYIWVYSGKGPTREHAKASAVMESIERYSALASVFFNEGRSNSILRSSMAEMVRKYGREHVLHPDDVVEAVSPNYNEYMRMDFLEGYDLISREHVWVPAGLVLTRYDVVASRNGAFNPFLYSHSNGLASGNSVEEAILQALCEVIERDAVSIAELRSSVLQFHVLKNSIEQLRAYGLRLRDIEHHYVDDPSIYPEVDLSGVEHPYARYLISRFEQEGIPLLVKDITSDIGVPTFIATSIQWITHDYGYLAEGHGTHPNKDVALIRAITEVSQTRAANIQGARDDLRRMNYEMGNTAENKAWQFMHSSKRIGYESIMDEKNGDVLDDIEFILERLKCNGLKRVIFVNLTDERLASVVRVIVPGLETFKVSKSVIGPRAMRYMHISSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD98</accession>
    <name>A0A2H5VD98_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00703</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000039">
        <property type="protein sequence ID" value="GBC74658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74658">
        <property type="protein sequence ID" value="GBC74658"/>
        <property type="gene ID" value="HRbin05_00703"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003933">
        <property type="term" value="F:GTP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007839">
        <property type="entry name" value="GTP_CycHdrlase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42202">
        <property type="entry name" value="PTHR42202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05165">
        <property type="entry name" value="GCH_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="185" mass="20274" checksum="E53092273DF7CC5D" modified="2018-02-28" version="1">MRIGIADTPYKAHKSAKMASSAVGRGLFVADDPNKLEGDGLVQIMHIDVDGSTTDVSSRLLPYQISLLVTRLHIEIAERFLEKGSLTFFLGGDNFMVVSSRLGKSEVEEAIRDVMTKTSVRLKCGIGIARDARSAAMLATRALDSIREMRKSMDGSKSKSKRIDIMQEDKSQVIPVDNVVELSCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDA0</accession>
    <name>A0A2H5VDA0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">4a-hydroxytetrahydrobiopterin dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.96</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000041">
        <property type="protein sequence ID" value="GBC74675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74675">
        <property type="protein sequence ID" value="GBC74675"/>
        <property type="gene ID" value="HRbin05_00720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="SSF55248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="106"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="106"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="135" mass="15556" checksum="E5574EF2AD1B0241" modified="2018-02-28" version="1">MVMEDIAKAIEVLKSKGWEYVDGRLSKQYILGSFIEAIEFVNDVAAVAESKKGRRFMSRQDSTNLTIVIEDKSVELILACDDVSMMMARAVDELYEMNYASERDEDELLKREEDRERARFRSRGPYRKSSSAGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDB1</accession>
    <name>A0A2H5VDB1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00731</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transcriptional regulator TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000044">
        <property type="protein sequence ID" value="GBC74685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74685">
        <property type="protein sequence ID" value="GBC74685"/>
        <property type="gene ID" value="HRbin05_00731"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021586">
        <property type="entry name" value="Tscrpt_reg_TrmB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11495">
        <property type="entry name" value="Regulator_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrmB" evidence="2">
        <location>
            <begin position="11"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Regulator_TrmB" evidence="3">
        <location>
            <begin position="116"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="256" mass="28425" checksum="0BF93C3ADEF2531E" modified="2018-02-28" version="1">MISEKARKAMEGIGLTSYEIKAYTTLLVEGALTAQELSIRAGVPYSKIYEVLGKLEEKGWIESDGSRPTKFYPRSPATALEAMKARMESEMRDAEATIVGELMPLYDKSGAKEKPEIWVLRGLHNILAKVKEVILGCEKELLVALPAVAEGMSKQMQPLLRQLREKGVRITILASESTSSEVIKALSRVAEVRFKDSMFGGGVISDSRQVILLLASERMGNEPLAILAEHTGLAGFAREYFNYLWKEARDIDYHSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDB8</accession>
    <name>A0A2H5VDB8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH_45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000042">
        <property type="protein sequence ID" value="GBC74678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74678">
        <property type="protein sequence ID" value="GBC74678"/>
        <property type="gene ID" value="HRbin05_00724"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038723">
        <property type="entry name" value="ArnR1-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14947">
        <property type="entry name" value="HTH_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_45" evidence="2">
        <location>
            <begin position="20"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="118" mass="13493" checksum="8A0C87B5204E7CEC" modified="2018-02-28" version="1">MKKNDDKSNKSDTMLENSRRRSREEILASVLVSAINGTTKTKIMYSNALNFAQVKYYINYAIESGFIRVYEDNTAGKRGRYIYVTTEKGLEYLKFYESLNTGKANASILSKKYSDKGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDC6</accession>
    <name>A0A2H5VDC6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal_L2_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00739</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000045">
        <property type="protein sequence ID" value="GBC74693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74693">
        <property type="protein sequence ID" value="GBC74693"/>
        <property type="gene ID" value="HRbin05_00739"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="5">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="89"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="103" mass="10996" checksum="EBEB63EEFE62ABCE" modified="2018-02-28" version="1">MPSGKFITLDAKCRGVIGSIAGGGRLEKPFLKAGAKWYAMRARSKKWPIVRGVAMAAPFHPHGGGRHQHPGKQTSVARNAPPGRKVGHIAPRKTGRGRVKRGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDC7</accession>
    <name>A0A2H5VDC7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Iron-dependent repressor IdeR</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ideR</name>
        <name evidence="6" type="ORF">HRbin05_00734</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DtxR/MntR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000044">
        <property type="protein sequence ID" value="GBC74688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74688">
        <property type="protein sequence ID" value="GBC74688"/>
        <property type="gene ID" value="HRbin05_00734"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="5">
        <location>
            <begin position="14"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="155" mass="17900" checksum="42A2BB330BAAE060" modified="2018-02-28" version="1">MEKEEALFIETAEREHIEMYLKAIWMLNERGEEAKVSVIARVLNIKQPSVVQMLRKLHRRGYVVYSNGKAELTDKGNEIGMQMIRNSRLLEVLMKNALKIDLDEEMVCGMEHHMSKRFADAICTLLNHPRICPHGYTIPEGECCKNNRLTESGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDC9</accession>
    <name>A0A2H5VDC9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase_PH_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00603</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74561">
        <property type="protein sequence ID" value="GBC74561"/>
        <property type="gene ID" value="HRbin05_00603"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_PH_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="74" mass="8253" checksum="6D1DD860628CFE81" modified="2018-02-28" version="1">MGEADMPVAYLPNLKQISLLQLDGKLTADEYRECLNLAISGCMQVYNMQREALMKKYFSTADNGGGEDDEEEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBC3</accession>
    <name>A0A2H5VBC3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00023</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73995">
        <property type="protein sequence ID" value="GBC73995"/>
        <property type="gene ID" value="HRbin05_00023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030230">
        <property type="entry name" value="Gpn1/Npa3/XAB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231">
        <property type="entry name" value="PTHR21231"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21231:SF8">
        <property type="entry name" value="PTHR21231:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC73995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="260" mass="28802" checksum="7DAE269BF65B1EFA" modified="2018-02-28" version="1">MYAVFILGTAGSGKSTLASRLVEWYVSKNAYAVTLNLDPGVIDLPYEPDVDVREYVSIDEIMSKYRLGPNGALILASDLIADRLDEIQRKVDELNPDYVIVDTPGQMELFAYRASGMFFAREFRCDAKASIFLFDPMLVNSPLNMLSIALLATSIRLRLGLAQVNVLSKIDLIKKDKLAELIECSADPARLEYALQREKDSELYLLGVSILKGLRRQGISMGLLAVSSLTYEGMVNLAGALARMLREGEDVENGDEMNYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBC8</accession>
    <name>A0A2H5VBC8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HRbin05_00022</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73994">
        <property type="protein sequence ID" value="GBC73994"/>
        <property type="gene ID" value="HRbin05_00022"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC73994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="326" mass="35698" checksum="ABEBF705E443F4AC" modified="2018-02-28" version="1">MRKGLGRVIAIIASIVPLILISLFLHVGVEDILSIGLFPFIVSCLIALAKLFIQGLRFHYYVRSFIGDGVAKMSSNVQIRMGSEFVTLTTPAYTGGEWVRVAWLYKNGVHSGKGLWIITIEIISDVLVGSTLAYIAMIIAFGAHNYVVSTAILVITTPVFVSYLILLTLSAKKTLQMPRFTRPLLTRLFGIEKGERWTNVMNDSLRVLCETSRMYLKRSSLRIFAVGLALTFVGAALHALTFMIVASAKASIGFFESLVMVAAAISIGTIPISPGGSGLTELGIAYYLNTFNIDPAAFGDVIIVWRIASYHVPLFVSWALLVRSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBC9</accession>
    <name>A0A2H5VBC9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Plastocyanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">petE_1</name>
        <name evidence="3" type="ORF">HRbin05_00016</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73988">
        <property type="protein sequence ID" value="GBC73988"/>
        <property type="gene ID" value="HRbin05_00016"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="domain" description="Copper-bind" evidence="2">
        <location>
            <begin position="65"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC73988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="313" mass="33610" checksum="511A3FEF8E248F49" modified="2018-02-28" version="1">MKYNYILTLGILSIAVASLTLYGNVKQASAAEFTIEIPAGAQNSTCNPTYSPSGDWTKMLSDKCFKPSTLTVPAGSTVTFVNKDTASHAMTFASNPLDASTWKLGDKKFDSGLVLPNGKWSVVLEEAGEHPYLCYVHPWMIGKVVVEAATPPEETRLITLTTDNNTVKIEVEFSSGTASDGMLTIDPPQEVTFNIRFIDPASGKLIDHVNYNFAVVDANGNVVSSKSEQHTHDGKAEQKVNFASTGAYTIDINVLGTGINKPFDTKHSGKSTLSISVVPEFPIGIVAVFASIAGIAVAISRFKGRLHIPMSNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBD2</accession>
    <name>A0A2H5VBD2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">(R)-stereoselective amidase</fullName>
            <ecNumber evidence="2">3.5.1.100</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ramA</name>
        <name evidence="2" type="ORF">HRbin05_00034</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.100" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74005">
        <property type="protein sequence ID" value="GBC74005"/>
        <property type="gene ID" value="HRbin05_00034"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="309" mass="34891" checksum="6EB7EAD9272C9274" modified="2018-02-28" version="1">MRRLRIASTQFILKPYSSLSSFMDDVSKMLDMSKGCDIVVFGEWFTLGLLSIDMDIDKATYDDIPRLARFTDDLCSRFSDLAIGRGQCIVAGTTVEEHSGRYYDTCFIFMPDGSMYRHRKTHLFPLEKDAWRMSEHDTMEVFEYSSRGCNNSYSSSIEQDGFSVKFGVCICYESQIPECSRVLALKGAELIVCPSLTLTDAGYNRIRHSCESRCIENQLLVVLSSTVGNLAPFPVRGIGRSAILAPCDKPWPSNGVIADGIMNVEHIVMAEVDLDGIKMTREHGAARTHRDRMEKIQLYSRWFASYLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBD8</accession>
    <name>A0A2H5VBD8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Antilisterial bacteriocin subtilosin biosynthesis protein AlbA</fullName>
            <ecNumber evidence="6">1.21.98.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">albA</name>
        <name evidence="6" type="ORF">HRbin05_00026</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.21.98.-" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73998">
        <property type="protein sequence ID" value="GBC73998"/>
        <property type="gene ID" value="HRbin05_00026"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="21"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC73998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="348" mass="40706" checksum="7C3F5E977187343F" modified="2018-02-28" version="1">MNAIRTIKVLGRWSLNRLQGKRMPLIAVFSMTHYCNYYCAMCPFGDPDKDAQMRLAMHRDLSTEQWMRIMSKVAPYVIWSIVEGGEPTSRKDILELLEHLKGLGLPVTMITNGSLLHTLDLDRLKQCVDYICLSIDSLRQESYCKIRGVKPETFKRVMSNLMLLKDHNIKHYINSVITKWNAEEFITQEYFDIAKNLGIKTVSMTFVEDRADVNYSLLPDRSTMVKVCNSILDYMERYDEPFILIPPLYWEQIIEYGRVLFDECGVWKSIFVNADGTVMVPCWKYKDNAYNLLEHDVEYVWSREEWAEVKHCRECDVLACIWYSSQSPTVLANGYMRGIRMLIRKHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBE0</accession>
    <name>A0A2H5VBE0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt-precorrin-8 methylmutase</fullName>
            <ecNumber evidence="6">5.4.99.60</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cbiC</name>
        <name evidence="6" type="ORF">HRbin05_00008</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.60" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73980">
        <property type="protein sequence ID" value="GBC73980"/>
        <property type="gene ID" value="HRbin05_00008"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043778">
        <property type="term" value="F:cobalt-precorrin-8 methylmutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016993">
        <property type="term" value="F:precorrin-8X methylmutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003722">
        <property type="entry name" value="Cbl_synth_CobH/CbiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036588">
        <property type="entry name" value="CobH/CbiC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02570">
        <property type="entry name" value="CbiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63965">
        <property type="entry name" value="SSF63965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiC" evidence="5">
        <location>
            <begin position="25"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC73980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="235" mass="26105" checksum="F19F35C8F8589D1E" modified="2018-02-28" version="1">MVVEEEEEEEKEKKEEKEAMSKGDEIEERSMQIIEEEVGSAKYNYASDEWIVVRRIIHATADFDYARSNIDSIVFSRNAIASALSAIGRRCSIVCDTDIIPAALNKSALKTLGLECISRISDQSVIEEASRSNRTRAEVAMRVMRDHISNGIVAIGNAPTALYELVRMVRDDGVKPMLVIALPVGFVSAVESKIMMMSVADEHGVEYISNRGRKGGSTVVAAILNALFKLYMQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBF1</accession>
    <name>A0A2H5VBF1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HRbin05_00047</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74016">
        <property type="protein sequence ID" value="GBC74016"/>
        <property type="gene ID" value="HRbin05_00047"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008138">
        <property type="term" value="F:protein tyrosine/serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026067">
        <property type="entry name" value="Dual_phosphatase_23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000242">
        <property type="entry name" value="PTP_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003595">
        <property type="entry name" value="Tyr_Pase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23339:SF26">
        <property type="entry name" value="PTHR23339:SF26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00782">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00700">
        <property type="entry name" value="PRTYPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00195">
        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00404">
        <property type="entry name" value="PTPc_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="1" id="KW-0488">Methylation</keyword>
    <keyword evidence="5" id="KW-0636">Prenylation</keyword>
    <keyword evidence="3" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="6">
        <location>
            <begin position="22"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="7">
        <location>
            <begin position="87"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="167" mass="18792" checksum="A07B3FA41F470B6F" modified="2018-02-28" version="1">MGNRLGDMARRVHGKIFGRPHNFSWVIDGLLAGSARPMSMQEMEWVKQVGIKSIVSVIEEPLPDEWLDGIVNYLHIPTLDYTAPDVEDMDRAVEFINSSIRDGKPVMVHCAAGKGRTGTVLAAYLIKYKGLSAVESINMIRSMRPGSIQSSRQEMALLLYERYIRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBF2</accession>
    <name>A0A2H5VBF2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00048</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74017">
        <property type="protein sequence ID" value="GBC74017"/>
        <property type="gene ID" value="HRbin05_00048"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="48" mass="5688" checksum="0A7954CD9E9CEEEA" modified="2018-02-28" version="1">MAKYDGIRGQELMDVEEKEDELILIFKDNRYLFVRVENGRLVTESVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBG9</accession>
    <name>A0A2H5VBG9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00073</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74042">
        <property type="protein sequence ID" value="GBC74042"/>
        <property type="gene ID" value="HRbin05_00073"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="582" mass="63225" checksum="07B2AEEF299B3FD1" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBH1</accession>
    <name>A0A2H5VBH1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74036">
        <property type="protein sequence ID" value="GBC74036"/>
        <property type="gene ID" value="HRbin05_00067"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="130" mass="15627" checksum="D6D9B4C160CBA202" modified="2018-02-28" version="1">MRKGYTQIVLKEEEAKKIEQFIKSDKRFEGRTFSNAAKTILLEYIEYHDYLRRYGPFLKFIGAEGNLIFIYDHFIDRIVEVEVHDRMLYCRYHGNSECAHIGFCFAVPELYRVFNEKGFKQPKRIVEDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBH2</accession>
    <name>A0A2H5VBH2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74029">
        <property type="protein sequence ID" value="GBC74029"/>
        <property type="gene ID" value="HRbin05_00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="413" mass="45368" checksum="802C4BF564E67F3E" modified="2018-02-28" version="1">MQKRVITLTIIAALLISSSIVYADTLSWEFYNDVLVSNADTSYRKIEAHIMKHPTDGNILMAAFLDYAAHSGAERRCRVATSTDGGATWTDRGYLPLPTGTYISVDPAVAVSKVGDTIRWYVACLALSDSIKYYNKNDVSKIYYSTSTDNGATWSSPTVVAEAKCVDDNPTYDYPYADEDCPIVDKPWIAVNGSNVYLCWARMSDFSRWSYKDSNGNYPYSSPIAIFFKRVGSTNDPIRLDSGTSWQANNSVSDRSVQGCNIAVNTSNGIIYVAWTKLTGDTTASIRMKRSFDNGNTFDNTQIIASPNRIPPSAGTCTDAFGCVIGITINGQQSGFRVNNFPYLAIDSSNNLHLTWTGYNSTASPPNTNIMYRKITNCITQGQNCSRSSAVNVVNEVLQQGSVLAFNNILKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBH9</accession>
    <name>A0A2H5VBH9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74044">
        <property type="protein sequence ID" value="GBC74044"/>
        <property type="gene ID" value="HRbin05_00075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="148" mass="16692" checksum="D00CDAE66A64B924" modified="2018-02-28" version="1">MPIRKIDAIAIALLLVYFAVLPKIEQPFITTFFIFWITAYTLDAASTVLSRNITYETNRIFALFARMLGPLPALAVHFAIEVLFITFLPFVFLRMLSIEASAFIAMVTGMLHAYAALSNIMFRPSSSSSSTTNKSIYFGSYRLHTLYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBI3</accession>
    <name>A0A2H5VBI3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00074</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74043">
        <property type="protein sequence ID" value="GBC74043"/>
        <property type="gene ID" value="HRbin05_00074"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="228" mass="25906" checksum="13022F6179D650F2" modified="2018-02-28" version="1">MVEVLWFEDIEPLKQPVFDFPLLGRISMKQMGIVGSASIIALASRDILIAMASLTIALFVAMTRYRAVSMDEFIYSLILYGMKHKVKPSIEIIFRYVNELLLNNGYSRIILARMVNKICNEIRCRLDKKYAYSSNGRGVRCYEDNIIILNSNTVRLRLRLLTKDGRAIANRLARIYVDDDLLTNITSDNNGELDVILSLTSTKNSNLRVYVDGYSKPLLEKVVTVISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBI9</accession>
    <name>A0A2H5VBI9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase</fullName>
            <ecNumber evidence="3">5.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">topB</name>
        <name evidence="8" type="ORF">HRbin05_00087</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74056">
        <property type="protein sequence ID" value="GBC74056"/>
        <property type="gene ID" value="HRbin05_00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11390">
        <property type="entry name" value="PTHR11390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="7">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="598" mass="68362" checksum="541D79DB00576129" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBK7</accession>
    <name>A0A2H5VBK7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00099</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74068">
        <property type="protein sequence ID" value="GBC74068"/>
        <property type="gene ID" value="HRbin05_00099"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="25"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="154" mass="17955" checksum="605BB922CA2AFF70" modified="2018-02-28" version="1">MNYMSIEESIKRHSFFRDIGIGIDLSSIARYAQHTTFEADNFIFREGEDADAFYLITHGKVSLELSTAHRGRIIIQTIDEDDVLGISWLFPPYKWHFDARALTLTRLIRIDAAHVRRMCDEDNVFGYRVMSKLASIVMKRLQAVRLQLLEIEEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBK9</accession>
    <name>A0A2H5VBK9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anaerobic sulfite reductase subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">asrA</name>
        <name evidence="2" type="ORF">HRbin05_00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74069">
        <property type="protein sequence ID" value="GBC74069"/>
        <property type="gene ID" value="HRbin05_00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17179">
        <property type="entry name" value="Fer4_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="253"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="334"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="374" mass="42931" checksum="DE6ACBC25D7E4E3F" modified="2018-02-28" version="1">MPFIVERDEFNGFFTALRDMGYEIIGPRVRDSVIVYDRLDSVDDLPIGMTEQQEKGVYRLRKRDDGALFGYTVGPHSWKMYLFPPRIRLFTAERHDNNLKIVEEQYNEKRLAFVGVRACELHAIQIQDRVFLNGTFKDPVYEKQRKNVFILAVNCTVSSSTCFCTSMNTGPMVGSGYDLVVTEVLKPRHQFLVDVGTSLGHELLSKVKHREASREEVEHALSMVEENAKAMSMMGRRRIDTKNIKELLYSSYESKHWDDVAERCLACANCTMVCPTCFCSTMEDVVDLKGEHAERWRLWDSCFSDEFTYIHGSTVRRSRGAKYRQWITHKLASWIDQFGTSGCVGCGRCITWCPVGIDITEEVKALQQGYAADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBL5</accession>
    <name>A0A2H5VBL5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Copper-containing nitrite reductase</fullName>
            <ecNumber evidence="4">1.7.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">aniA</name>
        <name evidence="9" type="ORF">HRbin05_00109</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Fe(III)-[cytochrome c] + H2O + nitric oxide = Fe(II)-[cytochrome c] + 2 H(+) + nitrite</text>
            <dbReference type="Rhea" id="RHEA:15233"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(+)</name>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.1" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74077">
        <property type="protein sequence ID" value="GBC74077"/>
        <property type="gene ID" value="HRbin05_00109"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050421">
        <property type="term" value="F:nitrite reductase (NO-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001287">
        <property type="entry name" value="NO2-reductase_Cu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00695">
        <property type="entry name" value="CUNO2RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plastocyanin-like" evidence="8">
        <location>
            <begin position="92"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="7">
        <location>
            <begin position="207"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="340" mass="38684" checksum="D056DAAD644ED7F7" modified="2018-02-28" version="1">MNVKPSVAVLLLAAVTLVSIFVVNADYNTSSIDVHISSMHNNVERSSIDPDKFLTNFDYGRVFVLDDGTVLREFTITVKDVRLEIAPNIYFDAWTYNGTIPGPTLRATEGDRVRVTFINDGSQPHTIHFHGKHPAEMDGVFPMIPPGGRFVYEFTAEPYGLHLYHCHVSPVAEHINRGLYGVFIVDPKIPREPAKEIVMVLNSYDTDFDKENNFYTVNGIPFHYVKNPIEVKRGELVRIYLVNMTEFDPINNFHLHGDLFKLYRTGTSYVPDEFTDMITLSQGERAILEFRYDYLGLYMFHAHVIEFSDKGWMGFFKVVDDYGNDDDSNDASAINGNDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBL9</accession>
    <name>A0A2H5VBL9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00116</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74084">
        <property type="protein sequence ID" value="GBC74084"/>
        <property type="gene ID" value="HRbin05_00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="186" mass="19986" checksum="788AC39CC359CBE3" modified="2018-02-28" version="1">MVGNIAIGDWSSRFMVAAIIQGLLVTILTLSIVIGQMYVKPEVSRVIAFGSAGMWFTMGYIMYVVVGVIGVAVSALFYHYLEHTLTAAYRGIARYLAWTHLIMMNVGITGATWLMMYGGYEAAKVMLPVNVGGLGLTAAEAHEVLAPLVMPIAAFIIVLAVGVVLGGIGFMVTYRNSMKTMRIAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBM6</accession>
    <name>A0A2H5VBM6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidyl-myo-inositol mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.345</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pimA</name>
        <name evidence="3" type="ORF">HRbin05_00126</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.345" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74093">
        <property type="protein sequence ID" value="GBC74093"/>
        <property type="gene ID" value="HRbin05_00126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043750">
        <property type="term" value="F:phosphatidylinositol alpha-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="44"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="228"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="414" mass="47989" checksum="72C4B04A556DEB41" modified="2018-02-28" version="1">MVIEKSYIIYIRIIMLEDLTSNKLYRDKLNILHIVQYDFEIFKGGIQRYVKELSEIQALKGYNVVVYSCSKEPTTKNVNGVTIKRFNYLEVFRTPISISMILSLLKEERFDIIHIHAQFPLVAELITLIAWLRRIPIVITYHNEVELTNMSLVTRLAYKIWSITLLKIMLYLSKIIIVTTREFALTSPILSNNKYKDKIHIIPIGVFINNSSNNINIVNITDNKTLAHKNYILYVGRIKPEKGIHILIQAISLLKEIKIDINLFIIGEATRYDELKYKNELEKLVADLELNKNVVFCGRVSDEELHTYYKNAIALVLPSTSRLEGFGIVQLEAMRHGIPIIVSDIPGPKSVSEGVSIPVKPHPYDISQAILKVLDNDYREKIRILSLCKIQEYKWDKIADKIEYLYHSIKNKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBM8</accession>
    <name>A0A2H5VBM8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74102">
        <property type="protein sequence ID" value="GBC74102"/>
        <property type="gene ID" value="HRbin05_00135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="151" mass="17108" checksum="1CD513347EFFA587" modified="2018-02-28" version="1">MINNDMNNMVNNTNVDISMLLYSIEDLIKENVGNVIIWDEKSKHMKGKYFYINIGKDMQVGILLGFIMDDNGRAKKCLALCFTDPKGRVDKSIAIRTENLFNSIIKKLEGFTIVKDDLPALIRTLTINDESKAIEFFKSSLLLLVNALTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBN0</accession>
    <name>A0A2H5VBN0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GDP-mannose-dependent alpha-(1-6)-phosphatidylinositol monomannoside mannosyltransferase</fullName>
            <ecNumber evidence="3">2.4.1.345</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pimB</name>
        <name evidence="3" type="ORF">HRbin05_00127</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.345" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74094">
        <property type="protein sequence ID" value="GBC74094"/>
        <property type="gene ID" value="HRbin05_00127"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043750">
        <property type="term" value="F:phosphatidylinositol alpha-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="187"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="381" mass="42859" checksum="B11C569A9AFA58E4" modified="2018-02-28" version="1">MKILVTTPYFYPEGGGLEKYAYNIFKGLAQKGHEVTIFCSTKKGYDINEKMDGLMVHRLKPDLIISNTPIRFNLFDILDKELKDGNYDIVNGHTPVPYFAEMATFVSRKRKVCDIVTFHAGKMVSSKPLLNAISKSLSITIEQLMFTITDKIIVVNELVKNGYLARFASKTEVVPPGVDTKRYIPSTVYNAEGKKLLFISPLNPSYEWKGVRVLLDAMPTVIKRHPDTILTIIGDGPLRQELMHICRIKQIDKNVIFRGRLSEDDLIKAYQESTLLIVPSTTDAESFPIVSLEANACGIPVIASRVGGIPYYVKDGINGFLVEPKNSSALAAKITELLSKSELLKEYSLKSRERALEFDWEIAIERTQSIFEQLLEGVRCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBN3</accession>
    <name>A0A2H5VBN3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00132</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74099">
        <property type="protein sequence ID" value="GBC74099"/>
        <property type="gene ID" value="HRbin05_00132"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="54" mass="6481" checksum="80F018B5A4C0A4E9" modified="2018-02-28" version="1">MTMKDERVQQYGYRCIAEVELAFSFINMMFDGEHVIARVYQRLKSYGYHSIINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBP5</accession>
    <name>A0A2H5VBP5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="3">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">GTP cyclohydrolase I</fullName>
            <shortName evidence="3">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">folE</name>
        <name evidence="6" type="ORF">HRbin05_00029</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74001">
        <property type="protein sequence ID" value="GBC74001"/>
        <property type="gene ID" value="HRbin05_00029"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="5">
        <location>
            <begin position="73"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="253" mass="28711" checksum="5E8253C5539E93A7" modified="2018-02-28" version="1">MRKVSSDGDYHNYDEYAHVKSSGSNNKSVDDADMGKGIRKESNSIGGKAKSSNGDGKERRGSTSKRHSTARIKRLIRQLLIELGEDPDREGLVDTPERVAEMYAEIFSGYSMDSELDVTFSEESDVVVAREIQFYSMCEHHILPFFGKVHIAYIPDGKVFGISKLVRLVEKYAKRLQIQERMTKQIADELKDKVKGVLVVVEGDHMCMRMRGVKNNSRILTIAYRGEFENREVREQVLSLLMDSSSGARMYDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBP9</accession>
    <name>A0A2H5VBP9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amicyanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mauC_1</name>
        <name evidence="3" type="ORF">HRbin05_00149</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74116">
        <property type="protein sequence ID" value="GBC74116"/>
        <property type="gene ID" value="HRbin05_00149"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="Copper-bind" evidence="2">
        <location>
            <begin position="53"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="310" mass="34729" checksum="0277EB2D4363940A" modified="2018-02-28" version="1">MILPNIVIYLVITIVTAMVYIPAVYADGAIVEIPRNAGDPSFDPQFPRPIEWYIPTNLKITVGDTVTWINNDTVTHTVTSGKGVSRYEGITGKLGVADGKFDSGLIERGERWSYKFDEPGTFTYFCTIHPWMIGSVVVEQRIPDYPHDANGNRLTLPVMTITSDRKYHVGVAWAPPVIKTGESIAFINDFFDVSGTIKQHLLKYYFVLYQNGKEIYRSLGYSERGSDVKYFVFSEPGPIIIRFEEIGGSPDNNAEFSTIVYANDDDSTIAFTSTISTAKIDTAIIHMITYAGITGLVVSAGVIYWWFRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBQ4</accession>
    <name>A0A2H5VBQ4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00042</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74011">
        <property type="protein sequence ID" value="GBC74011"/>
        <property type="gene ID" value="HRbin05_00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030677">
        <property type="term" value="C:ribonuclease P complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016432">
        <property type="entry name" value="RNP4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007175">
        <property type="entry name" value="Rpr2/Snm1/Rpp21"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04032">
        <property type="entry name" value="Rpr2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004878">
        <property type="entry name" value="RNase_P_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="91" mass="10868" checksum="D15C7D51224DC78E" modified="2018-02-28" version="1">MEILLRNVLDTAKYDHTLAEKQAMLIRRISMRYRIRLPYEVRQLFCKRCKRLIIPGVTSRVRIGRSSIRAIRITCLHCNHIYRKIIDSKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBR8</accession>
    <name>A0A2H5VBR8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74142">
        <property type="protein sequence ID" value="GBC74142"/>
        <property type="gene ID" value="HRbin05_00175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="48" mass="5612" checksum="65F0D4813054AA37" modified="2018-02-28" version="1">MIIEMGNNNSISNSDSRRRGRGRRGDEGRRRGRRKEKEDRDKPRDALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBS0</accession>
    <name>A0A2H5VBS0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00168</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74135">
        <property type="protein sequence ID" value="GBC74135"/>
        <property type="gene ID" value="HRbin05_00168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="94" mass="11027" checksum="2EE31DBE9EEF72B1" modified="2018-02-28" version="1">MDGEEELKEEGERNKDARGGSEEAKYKHLIEHKGHDVICMRCNLLALEFIDYEKALKSKRPSIYARNKCLCIYKDEFYCNDCKVKITLDTQSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBT8</accession>
    <name>A0A2H5VBT8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-deoxynucleotidase</fullName>
            <ecNumber evidence="5">3.1.3.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">yfbR</name>
        <name evidence="7" type="ORF">HRbin05_00190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-deoxyribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36167"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18274"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:65317"/>
            <dbReference type="EC" id="3.1.3.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.89" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74156">
        <property type="protein sequence ID" value="GBC74156"/>
        <property type="gene ID" value="HRbin05_00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002953">
        <property type="term" value="F:5'-deoxynucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039356">
        <property type="entry name" value="YfbR/HDDC2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11845">
        <property type="entry name" value="PTHR11845"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13023">
        <property type="entry name" value="HD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="6">
        <location>
            <begin position="33"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="175" mass="20429" checksum="1D6B3A676FD199ED" modified="2018-02-28" version="1">MLEFFLTACRLKRVKRKGWLVKANVSRDDAESVADHSYMLALIAMIIADAKGLDTCKTMRMALLHDIAESITGDYMPEEIEQKEKRMLEHDAMLKLLTMLPEGLRDEYSRLWDEYLNCRSEEARLVHELDKVEMVIQARCYEDMGYTDVLRRFYSYAEPYVSDDIARKLLSSINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBT9</accession>
    <name>A0A2H5VBT9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2H2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00188</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74154">
        <property type="protein sequence ID" value="GBC74154"/>
        <property type="gene ID" value="HRbin05_00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="SMART" id="SM00355">
        <property type="entry name" value="ZnF_C2H2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2H2-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="43" mass="4938" checksum="F47352A2B7218F52" modified="2018-02-28" version="1">MSKESKVRCPYCESTFNSKEELSKHIDRMHIGPGVLEGDTRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBU4</accession>
    <name>A0A2H5VBU4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00192</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74158">
        <property type="protein sequence ID" value="GBC74158"/>
        <property type="gene ID" value="HRbin05_00192"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="94" mass="10289" checksum="CDAA0B28586AABE3" modified="2018-02-28" version="1">MQEEVEGIIGEVEGRKGGEEGTIPTIATTSKAAITTDNLLHYKVPNTKDFDLEITDTEYVIVTGSSTIHIERREGNTTITVTIREGVVTDILVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBV3</accession>
    <name>A0A2H5VBV3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00202</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74168">
        <property type="protein sequence ID" value="GBC74168"/>
        <property type="gene ID" value="HRbin05_00202"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="348" mass="38959" checksum="5AFE3E42741D551A" modified="2018-02-28" version="1">MQHRLGMKYRYRDIMDGIAIKNNIDQSSLNADSIVLDCDGTLVRINRSYNACIVETAGRILSSMLGDEWKDFVDEQMILAFRMSGGFNNDVDTTFACILAALAYNDDSNHADVDNARIFAHEIARHADSRGVESVEEYLASIGKAHVVKAAREYTGYPGLVGSSMLATLFDELFYGKELFIAMHGIEPRFNHGRGFIEYDEVVVSKDCLSMLNERFDGKVAIVSGRSRIAAEYALRDLLGYFNLKASVFIEDEDKYVKRNGLRMNVVKPNPYALLKSMKVMNVNNAIVVGDSAEDLIMARSASNDHGYRTYFVGVYGTSIDAEKQKQMFINMGSDAIIENINLLLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBV6</accession>
    <name>A0A2H5VBV6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="6">2.6.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hisC</name>
        <name evidence="6" type="ORF">HRbin05_00201</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74167">
        <property type="protein sequence ID" value="GBC74167"/>
        <property type="gene ID" value="HRbin05_00201"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="5">
        <location>
            <begin position="40"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="19"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="363" mass="41239" checksum="81A9C6FDD5CA8C9E" modified="2018-02-28" version="1">MVMRIGWLRHRLERLSRLEGYTKPERPQHQPRSGSHSPIRMDTNENIALPLEFVREVMQEALDGVDPRFYPEQYDELRSSISSYLGLSKDNIVIGNGSDQLIDLALVAFGYGRRSVTVNPTFTFYKDRCLLHGIEVEEVMLDDNFSFSADSILKSSADIFYIPSPNNPTGNQFAKDLMLDVIERFNGLVMVDEAYAEFAGYSLKDLAVERDNLIIFRTFSKAFGLAGARVGYAIACKEMADVFNRVIQYPYAVSSISLKAAISILKRSEQVKRVIEYLKAERGWLYEQLSMLGIRAFKSDANFILFDLDGYEDVYRRLRDEEGILIRKIGRVGGYKGCLRATVGSRDMNEMLLNGLAKIVGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBW1</accession>
    <name>A0A2H5VBW1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00213</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74179">
        <property type="protein sequence ID" value="GBC74179"/>
        <property type="gene ID" value="HRbin05_00213"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="35" mass="4237" checksum="DA01176BF1C50912" modified="2018-02-28" version="1">MLAYKLIVRGRADRKLTSRIIRYYLDNLLLTEVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBX6</accession>
    <name>A0A2H5VBX6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">2-(3-amino-3-carboxypropyl)histidine synthase</fullName>
            <ecNumber evidence="3 6">2.5.1.108</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HRbin05_00221</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + H(+) + S-methyl-5'-thioadenosine</text>
            <dbReference type="Rhea" id="RHEA:36783"/>
            <dbReference type="Rhea" id="RHEA-COMP:9748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9749"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73995"/>
            <dbReference type="EC" id="2.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DPH1/DPH2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.108" evidence="3 6"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74187">
        <property type="protein sequence ID" value="GBC74187"/>
        <property type="gene ID" value="HRbin05_00221"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090560">
        <property type="term" value="F:2-(3-amino-3-carboxypropyl)histidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11840">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11860">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016435">
        <property type="entry name" value="DPH1/DPH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042263">
        <property type="entry name" value="DPH1/DPH2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042264">
        <property type="entry name" value="DPH1/DPH2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042265">
        <property type="entry name" value="DPH1/DPH2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035435">
        <property type="entry name" value="DPH1/DPH2_euk_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022428">
        <property type="entry name" value="Dph2_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10762">
        <property type="entry name" value="PTHR10762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01866">
        <property type="entry name" value="Diphthamide_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004967">
        <property type="entry name" value="DPH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00032">
        <property type="entry name" value="Radical_SAM_3-amino-3-carboxyp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03682">
        <property type="entry name" value="arCOG04112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00322">
        <property type="entry name" value="diphth2_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="335" mass="37844" checksum="386BE71467FFD4D2" modified="2018-02-28" version="1">MIHIDEERIFSIIRERKPRVVAFNGPEALLGKISIIADKVSKEFCIDAYVIADPCYGSCDLNTDAAKRLNADILFHVGHSISMREFGNVVFIDAYDDIQFDSVLAKCINMLKEKGIENVAVLTDSQHIHEVDNAIAILKQHGFNVVTTRGKGQLMDAQVFGCEFYPAFYARDDADAFIFLGQSTFHAVGVALSTGRLTLMLDPYYDEVKEVNSIAEMLKRRAFLAIYKALDAQRIGLIVGIKEGQMMLNRVKDIKSRLEAHGRSVRLIALTEVTEERLRIFNDIDAFIQVACPRISMDDEFSKPVLSVPQAYTLLKMLDKQSVEYDEFLVLPHWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBX8</accession>
    <name>A0A2H5VBX8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Proteasome subunit beta</fullName>
            <ecNumber evidence="9">3.4.25.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">20S proteasome beta subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Proteasome core protein PsmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">prcB_1</name>
        <name evidence="9" type="synonym">psmB</name>
        <name evidence="11" type="ORF">HRbin05_00233</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="9"/>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74199">
        <property type="protein sequence ID" value="GBC74199"/>
        <property type="gene ID" value="HRbin05_00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02113_A">
        <property type="entry name" value="Proteasome_B_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019983">
        <property type="entry name" value="Pept_T1A_Psome_bsu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03634">
        <property type="entry name" value="arc_protsome_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="7 9 11" id="KW-0647">Proteasome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="8 9" id="KW-0865">Zymogen</keyword>
    <feature type="propeptide" id="PRO_5014202271" description="Removed in mature form; by autocatalysis" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023420888" description="Proteasome subunit beta" evidence="9">
        <location>
            <begin position="21"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR600243-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="219" mass="23792" checksum="A41AEA2B7488453E" modified="2018-02-28" version="1">MLGGLFLHNNRYVESNRLHGTTTVGLQCKDGVVLATDTRATAGYLFIAHRHVRKIAKIDEHVALTIAGSVADAQSMIDILRYHASIYKLENRVPIPTKSVARLAANVFFAQRFYPLIAEILVGGYDSEGPSVYMVDLFGSVNKEVFVSTGSGSPVAYGILESEFKPDMSVDEAAKVATRAIAAAIMRNAGTGDGIDVVAIDKNGYRELSRRFVGLRLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBX9</accession>
    <name>A0A2H5VBX9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Regulatory protein AsnC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">asnC_1</name>
        <name evidence="6" type="ORF">HRbin05_00228</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74194">
        <property type="protein sequence ID" value="GBC74194"/>
        <property type="gene ID" value="HRbin05_00228"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="HTH asnC-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="159" mass="17858" checksum="BCDECF31400407A4" modified="2018-02-28" version="1">MLKRRGRKPRLLDEIDKSILSILHEDCLIPFVKIAKALNVNEGTIRHRVKRLVRSGIIKKFTIKVDPIMLGLGTLVLVIVVVSPGNVKYVAQELAKVPNVLEVLEVHTYGDLLLKVRGSNMQEIASILANQIKTIEGVISTQVISVLNVWKDEHPLFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBY0</accession>
    <name>A0A2H5VBY0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00236</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74202">
        <property type="protein sequence ID" value="GBC74202"/>
        <property type="gene ID" value="HRbin05_00236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="49" mass="5626" checksum="C90EAED9F5801A84" modified="2018-02-28" version="1">MAEPFIGTMYAMTGVFAAAVAVWFSIRAYRHSKMVEQEEEVREERTELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBZ2</accession>
    <name>A0A2H5VBZ2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00243</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74208">
        <property type="protein sequence ID" value="GBC74208"/>
        <property type="gene ID" value="HRbin05_00243"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040612">
        <property type="entry name" value="ArsA_HSP20-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17886">
        <property type="entry name" value="ArsA_HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="2">
        <location>
            <begin position="54"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="156" mass="18401" checksum="D66CBB0F32A77D3C" modified="2018-02-28" version="1">MGMSDEERRRREGEGEGERRDIFDVIEEMDRRMRRIMERALSSMIMDVDEQLYDIERRELKPLTQISETDEEVIVTLDIPCASKESIELKATEDTLFIRARMDRCITFSNVEFENYSKSVRLPARVEPKYARASFRNGILQVRLPKKFEGSEISIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC06</accession>
    <name>A0A2H5VC06_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HRbin05_00261</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74226">
        <property type="protein sequence ID" value="GBC74226"/>
        <property type="gene ID" value="HRbin05_00261"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017158">
        <property type="entry name" value="Tscrpt-reg_CBS-contain_prd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037253">
        <property type="entry name" value="HTH_CBS_prd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="3">
        <location>
            <begin position="8"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="4">
        <location>
            <begin position="70"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="128"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="219" mass="23952" checksum="CB73406B8C8FB347" modified="2018-02-28" version="1">MLPRLEYIKQARIRLGLTQRRLAMLAGVSTSMINQIESGRCKPSYDTAKRIFEILNSLEDRSSPKIVEICSKEIISVSVDDTLQDAIELMRKHSFSQLPVFADSKPVGMISEEGIVKYMMVKNDGDVDNGKDGGMVRSAGTEPSKASTPASKKGRSKRSKSLHECRVGEIMEPAPPIVDASTPAKAIIPLIRFSKCVLVGEKGNIVGIVTVADMFKLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC08</accession>
    <name>A0A2H5VC08_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 9">Peptide chain release factor subunit 1</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Translation termination factor aRF1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">prf1</name>
        <name evidence="11" type="ORF">HRbin05_00264</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 9">Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of two subunits, one of which binds GTP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the eukaryotic release factor 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74229">
        <property type="protein sequence ID" value="GBC74229"/>
        <property type="gene ID" value="HRbin05_00264"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00424">
        <property type="entry name" value="Rel_fact_arch_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005140">
        <property type="entry name" value="eRF1_1_Pelota"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024049">
        <property type="entry name" value="eRF1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005141">
        <property type="entry name" value="eRF1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005142">
        <property type="entry name" value="eRF1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020918">
        <property type="entry name" value="Peptide_chain-rel_aRF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004403">
        <property type="entry name" value="Peptide_chain-rel_eRF1/aRF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10113">
        <property type="entry name" value="PTHR10113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03463">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03464">
        <property type="entry name" value="eRF1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03465">
        <property type="entry name" value="eRF1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01194">
        <property type="entry name" value="eRF1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55481">
        <property type="entry name" value="SSF55481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03676">
        <property type="entry name" value="aRF1/eRF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="eRF1_1" evidence="10">
        <location>
            <begin position="1"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="415" mass="46669" checksum="A38C1F020F600D8B" modified="2018-02-28" version="1">MGKSDSVRLYRLKRMLNELSQKKGRGTELISLYIPQGKPIHEVIATLREEYGTASNIKSDSTRNHVLDALTKTMQRLKLYTKTPENGLVIFCGALPTNGLGSEVVKIFEIEPPKPLNIFLYRCDDHFHTEILKDMLKEEKVIGIIAIDSSEAGIGVLEGNKVEVVDHITSGVGGKHRAGGQSARRYERLREMELNDYFNRVAEHAKSLLIDTYNVVGLIVAGPGPTKDDFLKNGYLDYRLQKNVLAVLDISYAGREGVREALEKAQDILQEYRLMEEKRLVRRLFEEINSSKGLAVYGMQDVINALKSGVADIVLVNDNINRVRVEVVCKRCNAREERIVSMDKAIQVKQEMISSACSKCSSIDYDVYEQDLIEYMDELAMNTGARVEVISSSTEDGKMLESLGQIAAILRYRIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC12</accession>
    <name>A0A2H5VC12_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-phospho-L-lactate guanylyltransferase</fullName>
            <shortName evidence="1">LP guanylyltransferase</shortName>
            <ecNumber evidence="1">2.7.7.68</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">cofC</name>
        <name evidence="2" type="ORF">HRbin05_00267</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Guanylyltransferase that catalyzes the activation of (2S)-2-phospholactate (2-PL) as (2S)-lactyl-2-diphospho-5'-guanosine, via the condensation of 2-PL with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S)-2-phospholactate + GTP + H(+) = (2S)-lactyl-2-diphospho-5'-guanosine + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:63424"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:59435"/>
            <dbReference type="ChEBI" id="CHEBI:59906"/>
            <dbReference type="EC" id="2.7.7.68"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme F420 biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CofC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.68" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74232">
        <property type="protein sequence ID" value="GBC74232"/>
        <property type="gene ID" value="HRbin05_00267"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00071"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043814">
        <property type="term" value="F:phospholactate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052645">
        <property type="term" value="P:F420-0 metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02114">
        <property type="entry name" value="CofC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002835">
        <property type="entry name" value="CofC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40392">
        <property type="entry name" value="PTHR40392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01983">
        <property type="entry name" value="CofC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03552">
        <property type="entry name" value="F420_cofC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="211" mass="23389" checksum="C6DE70F2B1CEFBFF" modified="2018-02-28" version="1">MLRLCAIIPVKSLAKGKSRLATFLSMDERINLSIAMLRDMLGCLCSSPYIDSVIIVSSDPTIKGIAGEFNTVLVEDEYEQGVNSAVALADNIASRYDASVVLPHDIPLISAFDVLMLYTSMLKHARCVVITPSSRLDGTNVLLRRPPDVIKTHYDEDSYKLHLDEALSSNVKVKILLSNRLMLDLDGIDDIYALISSNHECNTKRYLMSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC18</accession>
    <name>A0A2H5VC18_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Inner membrane protein alx</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">alx</name>
        <name evidence="6" type="ORF">HRbin05_00274</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74239">
        <property type="protein sequence ID" value="GBC74239"/>
        <property type="gene ID" value="HRbin05_00274"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022369">
        <property type="entry name" value="Integral_membrane_TerC_rswitch"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30238:SF0">
        <property type="entry name" value="PTHR30238:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03718">
        <property type="entry name" value="R_switched_Alx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="307" mass="34056" checksum="A58874445035544A" modified="2018-02-28" version="1">MLSSLTLLEFHIIVAVLIAVDLLVGMKRKHGMSIKESTIWSIVWIGFGVAFGVSLSYEYQTSDVLDYFTIFVLEKSLSVDNLFVFAAIFSYFATPVTARPVVLYVGVISAIVMRALFIYAGIAALEALPWLVFIFATILIYSGVKIWGNKTELTHIERNPIVRFAKRYLPIADRYDGNRFVLTKSPLLLSPLILVLFAIEASDLMFAVDSIPAALAISNDFTIVYTANIAAVLGLRSLYFLVDHLLFRFKYLNKGLGVVLALLGVKFLFEGFHIEIPKEVAVASTLSIIGASILLSIVSDRRNDSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC23</accession>
    <name>A0A2H5VC23_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00269</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74234">
        <property type="protein sequence ID" value="GBC74234"/>
        <property type="gene ID" value="HRbin05_00269"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="65" mass="6637" checksum="CEC91CFEBCD2D006" modified="2018-02-28" version="1">MVVEPFMASNVEGQGVPSKIKSVSSGNFPLMVLLAFAGMMGAIAGFGGQAGGNDRSSNLLYSIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC37</accession>
    <name>A0A2H5VC37_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HRbin05_00290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74255">
        <property type="protein sequence ID" value="GBC74255"/>
        <property type="gene ID" value="HRbin05_00290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022495">
        <property type="entry name" value="Bud32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12209">
        <property type="entry name" value="PTHR12209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03724">
        <property type="entry name" value="arch_bud32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="222" mass="25601" checksum="C939C13C3A5F837E" modified="2018-02-28" version="1">MLIKRGAEADIYLVEWYGRQAISKVRKRKQYMHEMLDREIRMRRTLHEAEMINMAKRAGVTTPLLYFVDPNNAEIIMQYIEGEVARDLIYQDVNVGWIAMMMGIYTARLHAKDIVHGDLTTSNFIVYNNATTSSNDNASADDAKRLVLIDFGLSFYSSRLEDKAVDIRLIKEVMSSAHADVFDELFNNFVQGYSSVVGNEYASRILKKVREIEKRGRYARVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC43</accession>
    <name>A0A2H5VC43_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00301</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74266">
        <property type="protein sequence ID" value="GBC74266"/>
        <property type="gene ID" value="HRbin05_00301"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="348" mass="39846" checksum="D077BD3ACE10F777" modified="2018-02-28" version="1">MAFRVFLNGYGTIGRRVAYALANDRDVEFIGVGKYSVDDRAKEAKDQGFKIFVPEAKIDEFKSKGYAVEGSIKDAIIASDLIVDASKDGLGYENKINYYLPLNKPAIFQGGEDRYGEHSVADIIHNSRVNYEQVYGKRYVIQGSCNVTGLGRIMQPLIERYGDEIVRFDATLIRRWADLEDKKEVKDSIEWDRDPHHQKDVADFIRSHALYVDVYKVPSRMMHLHQLYVRFKHECPSKDSILDVFEKEWGVALLSNAKGTADVRKKALELGFPFGDTCMVHIHTDVLKVQGDILKITYSDDQTGIVAPENHMLIQAMLFRRSKREALERTERIFRLNERKKALASEFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC59</accession>
    <name>A0A2H5VC59_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74161">
        <property type="protein sequence ID" value="GBC74161"/>
        <property type="gene ID" value="HRbin05_00195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="249" mass="27961" checksum="E7956A020D2ABF23" modified="2018-02-28" version="1">MFAEQLQAYSKNPVALARLHEGLKHIQEEGGVTAQDTNTLAGLIHFKDQLRNLAQEKYNIEIPNPEFELSDVRKPEELPAGATVIAAYPVKYTIANVIQDAEAMKLTATPEQLAELQVTGKEVIGEPEKLQKIVTNRVKDIIIERYNIRTDKDKAVQTFIKNLSTNITQDLVGRDPETVGAIYETISKDEKFLDLLVDMPDKELIKKTDQLLPNVHIQQLWREAKSQTQSGNSNRSSSNTGNRNNTVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC61</accession>
    <name>A0A2H5VC61_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nickel-responsive regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nikR</name>
        <name evidence="7" type="ORF">HRbin05_00285</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transcriptional regulatory CopG/NikR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74250">
        <property type="protein sequence ID" value="GBC74250"/>
        <property type="gene ID" value="HRbin05_00285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002145">
        <property type="entry name" value="CopG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014864">
        <property type="entry name" value="TF_NikR_Ni-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08753">
        <property type="entry name" value="NikR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01402">
        <property type="entry name" value="RHH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RHH_1" evidence="5">
        <location>
            <begin position="15"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="NikR_C" evidence="6">
        <location>
            <begin position="72"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="137" mass="15623" checksum="F9227883F8586FEE" modified="2018-02-28" version="1">MKGEEGTKGKEARIVSISLTDSMLKEIDELQKEFGFSGRSEVIRAGIRMLLTDRIEKERLAGSIGCVLIVTHDEEDEASTKIKLRYEDIIKTHLHCKLKNKKCLELFVIEGDAEKVKDMTREFQANEGMEHVRLIMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC62</accession>
    <name>A0A2H5VC62_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase</fullName>
            <ecNumber evidence="4">3.5.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ylmB</name>
        <name evidence="4" type="ORF">HRbin05_00320</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.-" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74283">
        <property type="protein sequence ID" value="GBC74283"/>
        <property type="gene ID" value="HRbin05_00320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010182">
        <property type="entry name" value="ArgE/DapE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01910">
        <property type="entry name" value="DapE-ArgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="3">
        <location>
            <begin position="186"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="400" mass="44170" checksum="E04262CBDB5627DA" modified="2018-02-28" version="1">MLYKIKDAVDSEMQRIVEDVRELIRIPSRNPPGEERRCAEYIHSRLKELGLNSILLHEPYADRPQVIAYARDSRFDELRIVLNGHIDTVPEGSMEGWSVDPFSGMIKDGKIYGRGAADMKSALAIMMHICKIVGRRDLLLCFAIGEERAEPGTSTILKHVRRLGIDRLRYGIVMEPTSLKIATCQMGALWLNVRVRGRSAHASIPTNGINAIVRACKAIGALEAYARDIAKRSISNSSSMISNGSRACIPRCSVTMIAGGVKENIVPDECSFTIDRRVAPYESANDVISEIKALLDAYAEEYEMSMIAERSPVCIDESSILVKGLSDALATIGITDHPVCWCFPGSTDNEHVVREGIESIVWGPGSIEQAHAADEHISIEELRLSTYALALLLSKLGYQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC63</accession>
    <name>A0A2H5VC63_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase</fullName>
            <ecNumber evidence="2">1.13.11.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hod</name>
        <name evidence="2" type="ORF">HRbin05_00310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.48" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74274">
        <property type="protein sequence ID" value="GBC74274"/>
        <property type="gene ID" value="HRbin05_00310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050586">
        <property type="term" value="F:3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="22"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="263" mass="30153" checksum="93A9E6355A0D1305" modified="2018-02-28" version="1">MKVTSDGLEIVYDDFGNGEPALLFMPGWCSDRTVFQDLMLRFTMHRRTLALDWRGHGESGSSKDDFGNEALVSDALAVIEASKAKQVIPVALAHSGWIAIELRRRLGVVVQKLILVDWILTEPPQSFIQVLRGMQDPYRWKDIVKDIFSHWLQDVDNPRLVNFVHKVMGSYGFDMWARAAREISKAYAEQASPLHALSLLRPPVSVLHIYAQSPVPDYLTIQQEFASSHSWFSVYRLDARSHFPMFEVPDEMVTVIEQFIRQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC68</accession>
    <name>A0A2H5VC68_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00322</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74285">
        <property type="protein sequence ID" value="GBC74285"/>
        <property type="gene ID" value="HRbin05_00322"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="10"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="294" mass="33485" checksum="110A8007C8128872" modified="2018-02-28" version="1">MLTYIEPLYRPPSEADSLILQVTIGCSYNRCSFCSMYRSKRYEERSWDEIKAEIDYASQEYPNTRRVFLADGDALNIKTEYMLSILDYLYRSFPKLERVSCYAMPKNLLQKSREELVALKDAGLKLLYIGIESGSDTVLRKVTKGATSKGIVEGCLKAKSAGIQLSCMLILGLGGRRYSKEHALESARVSSIIAPEYLAALTLLLDDVVRDEFMSKFGEPFEPLSDIEILDELKMLVEHIEPIDDKKIIFRANHASNPYPIKAVLPDDRARTMALIDELKARPDRLKASYLRRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC90</accession>
    <name>A0A2H5VC90_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00317</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74280">
        <property type="protein sequence ID" value="GBC74280"/>
        <property type="gene ID" value="HRbin05_00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="110" mass="13643" checksum="DB2BE45150E4C816" modified="2018-02-28" version="1">MPTIRLKHDLSDEQFKELQRYMDEMPIEYILAGLRFSYRRWLAKERGMLMVGRRSKVRQEVEMLTLEQARWRLENWSRMIKIYREKGYSYPTIHRIRKALMRIVNSYNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC91</accession>
    <name>A0A2H5VC91_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74312">
        <property type="protein sequence ID" value="GBC74312"/>
        <property type="gene ID" value="HRbin05_00350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="118" mass="13728" checksum="3DF9C30A2080A601" modified="2018-02-28" version="1">MDRDDLNDDKILRFFLERSLFSARQFDIIYRRIHGGRDLGISRGAYYRLLKQSREKVEGIIYSLLLLTYIGMLDGKKQEVLLQLLKQIDVISRSSADSDDVIYVMDVIDKLVKGLSRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC94</accession>
    <name>A0A2H5VC94_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00353</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74315">
        <property type="protein sequence ID" value="GBC74315"/>
        <property type="gene ID" value="HRbin05_00353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="79" mass="9074" checksum="C87910E83973988D" modified="2018-02-28" version="1">MAIVEVEIPDGALRFLRAMQILWQYPNGWVEQYLTNAILKSIEKDIDEGIIDRERVKEACGISKLYSQELPLNKEAIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCA2</accession>
    <name>A0A2H5VCA2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00361</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74323">
        <property type="protein sequence ID" value="GBC74323"/>
        <property type="gene ID" value="HRbin05_00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="36" mass="4322" checksum="0F375D628D51D442" modified="2018-02-28" version="1">MVLDEKRVPKEIYEWLISESLNLDVEGFKKRGNKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCB1</accession>
    <name>A0A2H5VCB1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CheY-P phosphatase CheC</fullName>
            <ecNumber evidence="2">3.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cheC</name>
        <name evidence="2" type="ORF">HRbin05_00371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74333">
        <property type="protein sequence ID" value="GBC74333"/>
        <property type="gene ID" value="HRbin05_00371"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="211" mass="22998" checksum="91B8E4065E75CADA" modified="2018-02-28" version="1">MSITAGGDVDDTKKRGDNRLDIISNILKFTILNRCVNAIDTMLNDKSSIDSISIEHITLDDIYERFDPEHVVFAVYIKGIGDIMLTLLLVIEVEDGKKLASILISNAIDGANVDELTTSAIAEFGNILLAGAFTNALTHFTGFNINCTAPGYAKDSLASILEYIVADSDSTEFIYADGKLSFVVNKDLVLHISVLIPINDAKRLVDVMLIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCB4</accession>
    <name>A0A2H5VCB4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mosB</name>
        <name evidence="6" type="synonym">pyrH</name>
        <name evidence="9" type="ORF">HRbin05_00362</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74324">
        <property type="protein sequence ID" value="GBC74324"/>
        <property type="gene ID" value="HRbin05_00362"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_A">
        <property type="entry name" value="PyrH_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011818">
        <property type="entry name" value="Uridylate_kinase_arch/spir"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02076">
        <property type="entry name" value="pyrH_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="26"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="30"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="139"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="251" mass="27273" checksum="FE3B91BF7F567763" modified="2018-02-28" version="1">MIDNSSSNSNSNSSNNNSNSKNSRGRVVIKLSGSIFDLYKVDTITPYAKMLREIWMGKSLQPIVIAGGGKEARLYIDVARVLGADESSLDEIGIEVSRLNARLLSYAIGVDIVYPSIPTNLEEVSMAASTGMVVVAGGLHPGQSTNATSALIAERVNAKLFINATDVEGIYTSDPRVHRDARLLKRVSVNELLSMLGRERFNAGTYELMDIVALKIIQRSRIPTRVVKADPQVIKDVIDGHDLGTEIVSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCB5</accession>
    <name>A0A2H5VCB5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bis(5'-nucleosyl)-tetraphosphatase, symmetrical</fullName>
            <ecNumber evidence="2">3.6.1.41</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">apaH</name>
        <name evidence="2" type="ORF">HRbin05_00365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.41" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74327">
        <property type="protein sequence ID" value="GBC74327"/>
        <property type="gene ID" value="HRbin05_00365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008803">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SER_THR_PHOSPHATASE" evidence="1">
        <location>
            <begin position="118"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="305" mass="34797" checksum="A588F1CB529C5082" modified="2018-02-28" version="1">MHEVDLRNLSSIDRAEFLSLLDNVMTTIKKERANARVGYNSIDGGLVKISSFKELVIIGDVHGDLNTLLAILEMVKFMDGHNILLFLGDYGDRGIMSVEVYYTLLYLKSRYPDRLIMLRGNHEGPMDLPFYPHDLPVMLEDKFGTHATQIYLRLRELFDLMYTGVLLDGLMLALHGGVPVNLNSLDDIAYSERMHPKSSNLQEILWNDPREIQGYRPSARGYGYYFGKDITEHALNAIGARLIVRAHEPCNGYKVNHDGLVLTLFSCKEPYGNDRASFMSISKDEYKVLVDDYSIERLLQHVNVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCC2</accession>
    <name>A0A2H5VCC2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxymethylglutaryl-CoA synthase</fullName>
            <ecNumber evidence="4">2.3.3.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mvaS</name>
        <name evidence="4" type="ORF">HRbin05_00381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. HMG-CoA synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.10" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74342">
        <property type="protein sequence ID" value="GBC74342"/>
        <property type="gene ID" value="HRbin05_00381"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004421">
        <property type="term" value="F:hydroxymethylglutaryl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006084">
        <property type="term" value="P:acetyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010142">
        <property type="term" value="P:farnesyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013746">
        <property type="entry name" value="HMG_CoA_synt_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013528">
        <property type="entry name" value="HMG_CoA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08540">
        <property type="entry name" value="HMG_CoA_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01154">
        <property type="entry name" value="HMG_CoA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HMG_CoA_synt_N" evidence="2">
        <location>
            <begin position="8"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="HMG_CoA_synt_C" evidence="3">
        <location>
            <begin position="187"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="469" mass="53301" checksum="5CA0DC242C67AA8B" modified="2018-02-28" version="1">MLLLIPMKPVGIDDIAIYVPPLYIDFKDFAEARKIDPSKLEFGIGIKKMAIVDADQDPACMAANACLRLMQKNDLKPSDIGRLYVATESGLDESKAMNSYVIGMLEQIYGQGSFEHCGGIECKFACVSGSYALYDNTNWIRCDEHNGKYAIVVVSDVAKYDIGSSGEYTQGAGAVAMLIKEEPRLLAFDQKVTSTVISNEHDFYRPFARSTPIVNGHYSNLAYLIYVKKAMLMYKQKAIETGLIKLRQDESIIDHIDLLAMHLPYSKMGKNALAFLLRHEWRNLPKWKHIIAKIGMEEPKPPEGMGTIEAILSDKEFMKKDEEFRRRFMETEEYKQVFESKLASSLKASEIIGNLYTGSLYMGFRSEIEYEYRKGKDLAGLRVGFASYGSGCSAMAFSGVIQDRYKEVVSRMDLEREIGERRRISMEEYEQLHRGLRSVEERIVSKSKEFVLVSIGKRGEGFREYTFHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCD2</accession>
    <name>A0A2H5VCD2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Elongation factor 1-beta</fullName>
            <shortName evidence="6">EF-1-beta</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">aEF-1beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ef1b</name>
        <name evidence="8" type="ORF">HRbin05_00392</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 6">Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the EF-1-beta/EF-1-delta family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74352">
        <property type="protein sequence ID" value="GBC74352"/>
        <property type="gene ID" value="HRbin05_00392"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00292">
        <property type="entry name" value="EF1B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00043">
        <property type="entry name" value="EF1_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036219">
        <property type="entry name" value="eEF-1beta-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014038">
        <property type="entry name" value="EF1B_bsu/dsu_GNE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004542">
        <property type="entry name" value="Transl_elong_EF1B_B_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39647">
        <property type="entry name" value="PTHR39647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00736">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006521">
        <property type="entry name" value="Transl_elong_EF1B_B_arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00888">
        <property type="entry name" value="EF1_GNE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54984">
        <property type="entry name" value="SSF54984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00489">
        <property type="entry name" value="aEF-1_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF1_GNE" evidence="7">
        <location>
            <begin position="3"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="92" mass="10107" checksum="00B3B6DF6123221C" modified="2018-02-28" version="1">MGRLITRVKIMPADIDVNLDALVEKVKGKMPDGVQVKRYSKEPIAFGINALLLDMVMDEDTADTDSLEEGLRSIDGVGEVEIVSMSRESARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCE5</accession>
    <name>A0A2H5VCE5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein NatA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">natA</name>
        <name evidence="5" type="ORF">HRbin05_00405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74365">
        <property type="protein sequence ID" value="GBC74365"/>
        <property type="gene ID" value="HRbin05_00405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="356" mass="40178" checksum="C46C966F88324FE9" modified="2018-02-28" version="1">MYAVETINLSRVFELKGKSVLALDDVSIRISKGEILGLLGANGAGKTTLVKILSTLLLPSKGSAYIHGYDVVRDAKHVRRMINLVSGGETPGYGMLTVRENLWFFSQLYGLSSSLARERIEMLIKDMELEQYRDVRMHKLSTGYKQRLNLARGFINDPRVLFLDEPTLGLDVINARHMRKYIRDWVDEDRTRTILLTTHYLAEAEEVCDKIAIIYKGRIVAYETPLALKASLSNGVSIQVEILSNDSTSSRSMMVEKISRSNGVLACMLEELGDGDEDDKGKMVKHSWSNGYGSNSRHNSSSNDERVTRLRIMLDDDSKIPDLVSTLVMNGYKVLSVMRDQPTLEDVYMRYMTSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCE8</accession>
    <name>A0A2H5VCE8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thiazole biosynthetic enzyme</fullName>
            <ecNumber evidence="2">5.3.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00394</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.29" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74354">
        <property type="protein sequence ID" value="GBC74354"/>
        <property type="gene ID" value="HRbin05_00394"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043917">
        <property type="term" value="F:ribose 1,5-bisphosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="435" mass="47623" checksum="420CC33115B742CA" modified="2018-02-28" version="1">MDMYDVIVIGGSISGLLAAREIAGRGFSVLVLEEDAEIGTPEHCGGLVSVDALNSLGIDEYRLLSRIKYATISVLDTTISIDAESKNVIAIDRRALDKHVAKQARRNGADIMLMCRARSFAVRDAYVKVDTNRGMMECKVLVDARGCSIPAGTGKGFLPSAQYEVDSACWIDDGRVEVYIDQDKYPGFFAWIIPGGKEKGRVGVSGRGISVVERLEEFITMKERGYGKSSDSSSSYDGSAYNHSHSHNHTDGYTHKCKDKGSDDRYGERYDDGGCVVLRKVFAPIWIDGPKRPFVKDGRVVVVGDAAGQAKPTTAGGIYTSGMGGLLAGTTIADALADNNLAILGRYEDAWLDLFGREFERMLMLRRLFERLDNKAIERILNSVYPHIDEVSASGDFDFHSSVLARMILSMDGLRVLKAVLGSEFRRFLASIAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCH7</accession>
    <name>A0A2H5VCH7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00439</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74399">
        <property type="protein sequence ID" value="GBC74399"/>
        <property type="gene ID" value="HRbin05_00439"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="163" mass="18109" checksum="A52D27AE3D89ACB2" modified="2018-02-28" version="1">MRKEYIVVRIDAAPDGSPYVFVSLAEPRDIKEKGQSPFGVQVVSNFTSFEDLMKNLNKMIASQLMGGFTTTLKLSIREYEESGIKVGDKIYIDIIKPDIMAGNELFLSQEQMQKYEKVLSILSEKGIGPSVWAAKRNQILAMINKGSSAEDIADTIIREVGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCI6</accession>
    <name>A0A2H5VCI6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative GTPase</fullName>
            <ecNumber evidence="2">3.6.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00449</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74409">
        <property type="protein sequence ID" value="GBC74409"/>
        <property type="gene ID" value="HRbin05_00449"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00750">
        <property type="entry name" value="lao"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="307" mass="32733" checksum="BF38542C5FD90FA8" modified="2018-02-28" version="1">MANIVDALLKGERWAIAKAISILEDDGIQAREIVEMIFKHSGNARVIGVTGPAGAGKSTLVGKMIGAYRARGFRVGVLAVDPSSSISGGAILGDRVRMQEHALDDGTYIRSMASRGASGGISAALRDAIRVLDVAGFNRIIVESVGAGQLDVKISSIVDLTIVVLNPQTGDSIQAIKAGLTEIGDIYVVNKADISGANTLYNDIKSLVVDGRDAIALKTVAVTGKGVDELIDAVEHSLSKKLSNGYKEMMRKRVESELMDIMLSMLSKVVQERIKKEEGGIIEKVLKKEMDPYNAAESIVAKVIRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCJ2</accession>
    <name>A0A2H5VCJ2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycerol-3-phosphate cytidylyltransferase</fullName>
            <ecNumber evidence="3">2.7.7.39</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tarD</name>
        <name evidence="3" type="ORF">HRbin05_00448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.39" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74408">
        <property type="protein sequence ID" value="GBC74408"/>
        <property type="gene ID" value="HRbin05_00448"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047348">
        <property type="term" value="F:glycerol-3-phosphate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="2">
        <location>
            <begin position="69"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="205" mass="22752" checksum="82873693AC186713" modified="2018-02-28" version="1">MDAIDKGILASLYIEDVVKRAGIGTPINEILDHHNLYVVAEHRRRLESLGMIKDGMLTELGRSAIRVVLTGGVFDIIHPGHIHTLRAAKSLGDVLVVVIARDSTVARLKGKKPLHDEGKRRELVASIRFVDLAMIGHESDIFKTVELIKPDIIALGYDQVHEEQFISKECQRRGLKAHIVRLTSPIPDLKSSMIKAELGSSIYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCL5</accession>
    <name>A0A2H5VCL5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Geranylgeranylglyceryl phosphate synthase</fullName>
            <shortName evidence="9">GGGP synthase</shortName>
            <shortName evidence="9">GGGPS</shortName>
            <ecNumber evidence="9">2.5.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">(S)-3-O-geranylgeranylglyceryl phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Phosphoglycerol geranylgeranyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HRbin05_00349</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(2E,6E,10E)-geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23404"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57677"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="9">Membrane lipid metabolism; glycerophospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GGGP/HepGP synthase family. Group II subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.41" evidence="9"/>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74311">
        <property type="protein sequence ID" value="GBC74311"/>
        <property type="gene ID" value="HRbin05_00349"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00940"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047294">
        <property type="term" value="F:phosphoglycerol geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02812">
        <property type="entry name" value="PcrB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00112">
        <property type="entry name" value="GGGP_HepGP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038597">
        <property type="entry name" value="GGGP/HepGP_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008205">
        <property type="entry name" value="GGGP_HepGP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010946">
        <property type="entry name" value="GGGP_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01884">
        <property type="entry name" value="PcrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01769">
        <property type="entry name" value="GGGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01768">
        <property type="entry name" value="GGGP-family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Glycerol-1-phosphate binding" evidence="9">
        <location>
            <begin position="171"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glycerol-1-phosphate binding" evidence="9">
        <location>
            <begin position="202"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glycerol-1-phosphate binding" evidence="9">
        <location>
            <begin position="224"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="248" mass="26327" checksum="312EEC1D3036A857" modified="2018-02-28" version="1">MGPVESRLFELSKKRPLCFILIDSESLEYDSASNMAKKAEELGADAILVGGSSVIDQIELDGVVASIKASAKIPVILFPGNITGISAKADAILFSSLLNSENPYFITQAQALGALYVKKHGLEAIPMGYLVIGEGSSVWFIGRARGVPMDKPKLAVMHALAAKYMGMRALYLEAGSGVHSSVRPEMVTAVRKNFDGLLLVGGGIKDEHTAVSLAKAGADVIVIGTLFEEGMYDTVGRIINGVRSLTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCL8</accession>
    <name>A0A2H5VCL8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00483</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74443">
        <property type="protein sequence ID" value="GBC74443"/>
        <property type="gene ID" value="HRbin05_00483"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="35"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="111" mass="12575" checksum="187473A8283ED77E" modified="2018-02-28" version="1">MRTEVYNVNDILDIMSKDGDWCCTFLQSRSMDAGVLRLKPGEDDPQSPHVNDEIYYIIKGDGFITIEGKDIPIKEGSVIFVPAKAKHKFHGHTKELIALYIFAGRDEDMTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCM8</accession>
    <name>A0A2H5VCM8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00489</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74449">
        <property type="protein sequence ID" value="GBC74449"/>
        <property type="gene ID" value="HRbin05_00489"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="72" mass="8286" checksum="D637020C29576EA8" modified="2018-02-28" version="1">MKLPCPVPDYTTIYRRVMALNIQIDDGKSIDGNEDIIIAVDDMNILDNSLFRYIRTTRILLVLYLETLLLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCN3</accession>
    <name>A0A2H5VCN3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phosphate-binding protein PstS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pstS</name>
        <name evidence="4" type="ORF">HRbin05_00460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74420">
        <property type="protein sequence ID" value="GBC74420"/>
        <property type="gene ID" value="HRbin05_00460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PBP_domain" evidence="3">
        <location>
            <begin position="59"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="360" mass="39439" checksum="6814789B9992CBF7" modified="2018-02-28" version="1">MNRNIAIAAIIAAVAVGVVVGVIGTVGIGTNTKTAPTTPAGTSAPAEAPVQIPTQTQVTRLSGSIVIDGSSTVYPITEAIAEEFSKKNPDVKVTVGISGTGGGFKRFTLGETDINDSSRPITDKERAAAKENNIRWVEIPIALEGLSIVVHRDNNLFPNDCISIEELREIWKPDSTIKKWSDLNPAYPAQEIRLYGAGPDSGTFDYFTEHVVGKARASRTDYIPSEDDNVLVQGVSTDRYSLGYIPLAYAEHAQDRLKILKVSKEKNGECIFPDGKSIIQGTYPLSRPLFIHVNYDKIQSRQELKEFVLFYLSNAKSAAEKVGYIPLSDTYYKDAIRLINEGRYTPDDDKTFVSIYKEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCP6</accession>
    <name>A0A2H5VCP6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74341">
        <property type="protein sequence ID" value="GBC74341"/>
        <property type="gene ID" value="HRbin05_00380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="168" mass="19403" checksum="474BE8950171A341" modified="2018-02-28" version="1">MDNNATLNDKVMSFLLLDIVMRIIKADPWWRSMSIDEVNEFLSRPLLLRLAVMDRDLYPIVHPLWFIYKDGIFYLEVHRTSKKARLLRGDGRVYFLVDEVVDGRPRGVRGKGNALILDDAELARKIMVEQVIKYLGSADKQLSKRLIDSSKDNVVVKVEPLVFATWIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCP8</accession>
    <name>A0A2H5VCP8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="7">1.2.1.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">asd2</name>
        <name evidence="9" type="ORF">HRbin05_00513</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7"/>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74472">
        <property type="protein sequence ID" value="GBC74472"/>
        <property type="gene ID" value="HRbin05_00513"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000319">
        <property type="entry name" value="Asp-semialdehyde_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005676">
        <property type="entry name" value="Asp_semi-ald_DH_pep-lack"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00978">
        <property type="entry name" value="asd_EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01103">
        <property type="entry name" value="ASD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="8">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="358" mass="39596" checksum="5DF61CDA48EFF5BB" modified="2018-02-28" version="1">MLKVAIIGATGVVGQEFIVALDKHPWFKVEAIAASERSAGKKYLDALRDSSTGIMKWHQRTPIPDYARDMVVKSVNEIDAKDYDLIFTAVESDDARIIEPKLAEHTPVISTAAAFRYEQDVPILIPGVNDEHAELLDVQRKRRGWKGFIAPLPNCTTTGLAITLKPIMDEFGIERVIMTSLQAVSGAGRSPGVAALDIFDNIIPFIPKEEEKVQVEAKKILGRLVDGRIDDARFRVSCTCTRVPVIDGHTECAFVETSKGCEPDDVKHAMLNYSKHVSIKDLPSAPQDYIIVHDDPSRPQPRLDRDVNDGMSTIVGRIRKDTAFENGVKYVLLSHNEKMGSAKGAVLLAEMLKVKELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCP9</accession>
    <name>A0A2H5VCP9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Threonine-phosphate decarboxylase</fullName>
            <ecNumber evidence="5">4.1.1.81</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">L-threonine-O-3-phosphate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cobD_1</name>
        <name evidence="11" type="ORF">HRbin05_00514</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + O-phospho-L-threonine = (R)-1-aminopropan-2-yl phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:11492"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58563"/>
            <dbReference type="ChEBI" id="CHEBI:58675"/>
            <dbReference type="EC" id="4.1.1.81"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.81" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74473">
        <property type="protein sequence ID" value="GBC74473"/>
        <property type="gene ID" value="HRbin05_00514"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005860">
        <property type="entry name" value="CobD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01140">
        <property type="entry name" value="L_thr_O3P_dcar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="10">
        <location>
            <begin position="36"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="372" mass="41294" checksum="7FDB01B3DAC3C2D6" modified="2018-02-28" version="1">MDGLPNIKPGVLAMKSIVHGGRHYILQSSRTQTQTLIDFSTSVNPLGPSPRVKEAIIKGIDGISEYPDNSARRFRMAAAEYIGVDYGCIVAGNGSSELIYLIADVLIAEGDRVLIIQPTFSEYERASLKNSAIVEHVMLDGFTFKDEHLNMLDEHMHGAKLLFICNPNNPTGLTVERGLLLRLVEEAYNEGVMVVLDECFMEFSSMDCSLARYVEEFNNLIVLRSLTKAFGLAGLRIGYCVTNPKLAGILADAKVPWSINALAEVAGVEALKDIEYVEMSRALLARERDYIHDRLESIGYYPLRSNVNFFLIKTPEGMNSTALRDMLLLKGILVRDCSNFFGLDDGRYIRVASRLRDDNELLIDAMGAVLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCQ5</accession>
    <name>A0A2H5VCQ5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 12">Probable cobalamin biosynthesis protein CobD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cobD_2</name>
        <name evidence="12" type="synonym">cobD</name>
        <name evidence="13" type="ORF">HRbin05_00516</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 12">Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 12">Cell membrane</location>
            <topology evidence="3 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the CobD/CbiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74475">
        <property type="protein sequence ID" value="GBC74475"/>
        <property type="gene ID" value="HRbin05_00516"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048472">
        <property type="term" value="F:threonine-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00024">
        <property type="entry name" value="CobD_CbiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004485">
        <property type="entry name" value="Cobalamin_biosynth_CobD/CbiB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34308">
        <property type="entry name" value="PTHR34308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03186">
        <property type="entry name" value="CobD_Cbib"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00380">
        <property type="entry name" value="cobD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 12" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="289"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GBC74475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="309" mass="34195" checksum="3C0F04069EA5A9DC" modified="2018-02-28" version="1">MYLIILVGALLLDLCVGEYPTRLHPTVWIGRVISLFKSRLKHGSKVREYVNGLIFAVALVVVVYLLAYNALSILEANSIAMMIIASILLLKSTFAIRAMEEHANVVINSLMRNDIAGARYSVSMIVGRDTSSLDEEHILSATIESIGESTVDGITAPLFYYALFGVAGALAYRAINTLDSMLGYRDEYHRYIGYASAKLDTIANYIPARLTALAMILAAWILGLDWRNAVRIMLRDRHKTPSINSGYPMSVVAGALRVRLEKIGYYRLGDGIEAITFEHCRLALRVMKLSSMLFIASVVLPLLIVHALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCR3</accession>
    <name>A0A2H5VCR3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="11">5.4.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">glmM_2</name>
        <name evidence="11" type="ORF">HRbin05_00491</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="11"/>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74450">
        <property type="protein sequence ID" value="GBC74450"/>
        <property type="gene ID" value="HRbin05_00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="7"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="148"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="243"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="378"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="430" mass="46752" checksum="A822124956FCE829" modified="2018-02-28" version="1">MGLKVSISGVRGLFPEDLTLEHVMNFTRVFSSMLSDRCALAMDTRISSKSIASVASAVLREYGIDVYNLGVAPTPVLVRESNASRVGAGIMVTASHNPLEWNGLKFALNGREVPADLLLKSSNSSKKSKSISRIGVEYWSSSSASSIYLDDLFRFLELDGYDAEGVRVAVDTAHGSSRAYILEILARLGFRAVVMDSIAVDPTGSDLAHLYTAVSNGCRLGIALDMDGDRAVVLTGQRYKPDDTLLICLAKAVEMGCRSIAVSIDTSNAVRDLARAMNCKLLYSKVGEANVVDTMLKNGCGAGGEGSSAGFIMAGFNLCRDGLLASALSLSMLDRLDEVMEYSKRYSVRRGKVDARGIKHDRISDLLLSRHDYSESITMDGIKLVLDESTWVLVRPSNTEDVVRLSVESESTDRCNELYRMYEQMIKDAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCS4</accession>
    <name>A0A2H5VCS4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00501</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74460">
        <property type="protein sequence ID" value="GBC74460"/>
        <property type="gene ID" value="HRbin05_00501"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="176" mass="19536" checksum="9496A437F2169254" modified="2018-02-28" version="1">MVRINLTIMNTVGMMVLLLSSFLGMGYAEGMEDGAHDKDRMHDTSKLHAASTVAGLHVELIVEPAVIEPNMPVRFSHEFMDSVTGELRDIVPHTFVIMKDGSIIFEEYAEHAGYVHEFIFKEEHKGPLTIMIKDVNNTGEDAGFTINVVPEFPAAMIVMITATASALLFGRRLMRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCT6</accession>
    <name>A0A2H5VCT6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Type II methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.113</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">N-4 cytosine-specific methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">dpnA</name>
        <name evidence="7" type="ORF">HRbin05_00546</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16857"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:13674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:137933"/>
            <dbReference type="EC" id="2.1.1.113"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.113" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74505">
        <property type="protein sequence ID" value="GBC74505"/>
        <property type="gene ID" value="HRbin05_00546"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015667">
        <property type="term" value="F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="6">
        <location>
            <begin position="33"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="255" mass="29446" checksum="0148A7661B4F6835" modified="2018-02-28" version="1">MLRCRSNNIMKIDEDHTIVFDDFHNVELDEKADMIFADPPFGIEFKANMATYNRSPDALSYVEIPSKEYPAFIKSLVGWCYTNLKDDGSMWLVSGWNNLRHVLDAVDDVGFITLNHVIWKYQFGVFTRKRFVTSHYHLLLLVKDKDRYTFNKPEHYAEDVWIIKRPYKHGEATAGNELPDELVERCIYTSSNKGDLVVDPVLGSGTTMKACRKMGRRCIGIEINPALEARIMRKLALHISNDNENMKLHDVNLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCU9</accession>
    <name>A0A2H5VCU9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1-pyrroline-5-carboxylate dehydrogenase 1</fullName>
            <ecNumber evidence="3">1.2.1.88</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rocA1</name>
        <name evidence="3" type="ORF">HRbin05_00565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000025">
        <property type="protein sequence ID" value="GBC74523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74523">
        <property type="protein sequence ID" value="GBC74523"/>
        <property type="gene ID" value="HRbin05_00565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:1-pyrroline-5-carboxylate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07124">
        <property type="entry name" value="ALDH_PutA-P5CDH-RocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005932">
        <property type="entry name" value="RocA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="53"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="523" mass="57792" checksum="1906FD234F94BD9A" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCV4</accession>
    <name>A0A2H5VCV4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent zinc metalloprotease FtsH 1</fullName>
            <ecNumber evidence="2">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ftsH1</name>
        <name evidence="2" type="ORF">HRbin05_00560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000025">
        <property type="protein sequence ID" value="GBC74518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74518">
        <property type="protein sequence ID" value="GBC74518"/>
        <property type="gene ID" value="HRbin05_00560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="34"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="407" mass="45799" checksum="1EA9132972911445" modified="2018-02-28" version="1">MWVERYRPKSIIEMVGNEDARLETYRWLAGWRQGDRPLLLIGPPGTGKTTMAKALANEFGYELFELNASDERTKERLEHLLKPLLENANIYSKRVLLFLDEVDGLHGTYDRGGLSALLSILKDASSIPVIMAANSDSGEVIKELRRVSKVVRMRGIPPRLLLLYLEHVLESEGKSMSIGDRLRVVVECNGDVRSMLNMAQSLVGMGVSGMEPISYSTPIDDAINSFFAARNIEEAVDALGRSEGFYVDPSFGYDSEKKRIDKLGALYSSIINASVDIDRMARLLEALSYADMLIARMNRLRMWSMFRYLDGIIAYSIFNDSRGLSYSQYDIPYNLSSKVFNEGRVLRMIVDAIASRLHESRHNVVAYYMPYIPLILGRKGSSTAVRIGEDYSITIDELESIAKSLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCW5</accession>
    <name>A0A2H5VCW5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proline dehydrogenase 1</fullName>
            <ecNumber evidence="3">1.5.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fadM</name>
        <name evidence="3" type="ORF">HRbin05_00566</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000025">
        <property type="protein sequence ID" value="GBC74524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74524">
        <property type="protein sequence ID" value="GBC74524"/>
        <property type="gene ID" value="HRbin05_00566"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006562">
        <property type="term" value="P:proline catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PTHR13914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pro_dh" evidence="2">
        <location>
            <begin position="10"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="131" mass="15215" checksum="CBC4C0309FD379A5" modified="2018-02-28" version="1">MHILESGGIVRLVKGAYREDASIAYRSKRHVNASFRRLMRILFKHSRGMFAIATHDNALIEEAIALSKEHQGKEFEFQMLKGIRDDLKHMLVRQGFKVAEYIPYGINISGYVYRRIRERPSNLLLLARSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCX4</accession>
    <name>A0A2H5VCX4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74538">
        <property type="protein sequence ID" value="GBC74538"/>
        <property type="gene ID" value="HRbin05_00580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="159" mass="17819" checksum="A67822C50DD69F82" modified="2018-02-28" version="1">MKCKPVQGSTHWDKIIFTIDVKQVPSTPTQPGNEELVKKLRPLIGKTLDIKVRDEPSEVVALEDTVKEFLAAKYSLSKQDLDYIMVKIVEVEYAIDPNVHGKGIPMDKQKTGMGKKSTETTPSTHTPNNEIYYAMPLMGIAGLGAFLAIRYRKEQKKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCX8</accession>
    <name>A0A2H5VCX8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00587</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74545">
        <property type="protein sequence ID" value="GBC74545"/>
        <property type="gene ID" value="HRbin05_00587"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="125" mass="14354" checksum="47CB90D011AB442B" modified="2018-02-28" version="1">MMANNSNYKEICNKILMLSPKIRYAGIINRFGKTIAGSMRSDVRPLFKPEEARDEFFLTAVKESMRERFYNSLGKCSFTLTVHEKVDLISFLHDKYIVYISVDKGLAYDDVGRIVKEANMLLASD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCZ0</accession>
    <name>A0A2H5VCZ0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PIN_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00596</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74554">
        <property type="protein sequence ID" value="GBC74554"/>
        <property type="gene ID" value="HRbin05_00596"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09876">
        <property type="entry name" value="PIN_Nob1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039907">
        <property type="entry name" value="NOB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033411">
        <property type="entry name" value="Ribonuclease_PIN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12814">
        <property type="entry name" value="PTHR12814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17146">
        <property type="entry name" value="PIN_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PIN_6" evidence="5">
        <location>
            <begin position="7"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="191" mass="21550" checksum="7639ACF508F6272F" modified="2018-02-28" version="1">MIKKKVIVLDATAFYAGIPLSSFSHPSIQYYTTSFVLDEVRHIKQSIDAINLLVNTGKLIVADPKQEYMEEARAYAEKVGEYDLSDADISIIALALMLQPSYEVTIASDDYGIVNVAMVIGLSISYITSRGIRYSGKWVRYCKVCRITYNDASKVCRVCGNRLRSRLVSSWRKEEEQKKMEGGREGGRENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCZ2</accession>
    <name>A0A2H5VCZ2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00601</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74559">
        <property type="protein sequence ID" value="GBC74559"/>
        <property type="gene ID" value="HRbin05_00601"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002674">
        <property type="entry name" value="Ribosomal_L37ae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011331">
        <property type="entry name" value="Ribosomal_L37ae/L37e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01780">
        <property type="entry name" value="Ribosomal_L37ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="92" mass="10563" checksum="32915CD2BCF4F696" modified="2018-02-28" version="1">MLLQEQESRSRTNNISMANSRVSGMKYKSESLKGLGAKYGATLRRRYTKIYLMLKRRRNCPMCGSIRFKREAIGIWKCGKCNYKVAGGAYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD02</accession>
    <name>A0A2H5VD02_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tyrosine recombinase XerC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">xerC</name>
        <name evidence="5" type="ORF">HRbin05_00607</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000029">
        <property type="protein sequence ID" value="GBC74565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74565">
        <property type="protein sequence ID" value="GBC74565"/>
        <property type="gene ID" value="HRbin05_00607"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="155"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="407"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="435" mass="50320" checksum="3F86F4B7F273E7E4" modified="2018-02-28" version="1">MGIANIGNSSDNSSSNARSNSNSSNRDIYKREERLKYWIERAKEDPYNSIEILKFVQYMQENGKAMLWIKACIVILLEISRILGKEFSSATKEDIKRVIEEIDSRDYSMHTVMKFRQVIKYFYKVVYGNNEYYPEVVRWIHKVSKDKKREHSSLSYDDFLTEEEVQRLIDTADTIQKKAFIAVGYETGSRPEELLNIRLKDILFDRLGAKIIVRGKTGERVTRVVVYVSLLKEWLNIHPYRNDREAYLWLSEATNHRWKPIGLRSAEKMFANIMKLAGIKKSTRLYILRHTRSTHLANRMTEAQLCSYFGWRLGTKVVQRYIHLAGINIDNTLASIAGLEDHKEESTLKVTRCRRCKEVLSPNNKFCIKCGLDVNEDYISNNELEKEVKELKEIVYEILRRLDLSSTSISSNSSGSISISSISSSTSSRSGGSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD05</accession>
    <name>A0A2H5VD05_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Quinolinate synthase</fullName>
            <ecNumber evidence="2 9">2.5.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">nadA</name>
        <name evidence="10" type="ORF">HRbin05_00615</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>dihydroxyacetone phosphate + iminosuccinate = H(+) + 2 H2O + phosphate + quinolinate</text>
            <dbReference type="Rhea" id="RHEA:25888"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
            <dbReference type="EC" id="2.5.1.72"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from iminoaspartate: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the quinolinate synthase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.72" evidence="2 9"/>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74573">
        <property type="protein sequence ID" value="GBC74573"/>
        <property type="gene ID" value="HRbin05_00615"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008987">
        <property type="term" value="F:quinolinate synthetase A activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10800">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00568">
        <property type="entry name" value="NadA_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003473">
        <property type="entry name" value="NadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036094">
        <property type="entry name" value="NadA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023066">
        <property type="entry name" value="Quinolinate_synth_type2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30573">
        <property type="entry name" value="PTHR30573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02445">
        <property type="entry name" value="NadA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142754">
        <property type="entry name" value="SSF142754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Iminoaspartate binding" evidence="9">
        <location>
            <begin position="114"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Iminoaspartate binding" evidence="9">
        <location>
            <begin position="201"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>iminosuccinate</name>
            <dbReference type="ChEBI" id="CHEBI:77875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="330" mass="36940" checksum="A59E96A80D9C1924" modified="2018-02-28" version="1">MDRVEVDLKQEIARLKRERDAVILAHNYQLPEVQDVADFIGDSLALSQKAASTDAKVIVFCGVHFMAETASIICPDKRVLIPDLEAGCSLASTITVEQLRAWKREHPDAVTVCYINTSADVKAECDYCCTSSNAVKVVKSIPEDKPVLFLPDMFLGAYVAEVTKRKNIYIWPGECHVHAGIRPSLVLEMLKTYRDAEFLIHPECGCTTSMVYYFGNGNGNGCVVNGNGNGNGISCNVKFLSTEGMMKYARQTSAKRLIVATEVGILYRMRKENPDKEFIPISSDAVCKYMKMITLDKVYRSLRDMVYEVKVPEETARRARRAIERMLAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD19</accession>
    <name>A0A2H5VD19_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Electron transfer flavoprotein-ubiquinone oxidoreductase</fullName>
            <ecNumber evidence="2">1.5.5.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00638</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.1" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000032">
        <property type="protein sequence ID" value="GBC74594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74594">
        <property type="protein sequence ID" value="GBC74594"/>
        <property type="gene ID" value="HRbin05_00638"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004174">
        <property type="term" value="F:electron-transferring-flavoprotein dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039651">
        <property type="entry name" value="FixC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43624">
        <property type="entry name" value="PTHR43624"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="644" mass="72968" checksum="914D2CB777D520E2" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD36</accession>
    <name>A0A2H5VD36_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74606">
        <property type="protein sequence ID" value="GBC74606"/>
        <property type="gene ID" value="HRbin05_00650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="92" mass="10772" checksum="247B35454B7A2988" modified="2018-02-28" version="1">MLEQKDSGYEHEDEQQQEQMLIKRFEELVAKYGKSENLKMFIYFHKPGSSVKHPPDVTDNIIYVLDGKRVKVRCRCGASLDLTDYSKMDKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD38</accession>
    <name>A0A2H5VD38_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Putative transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HRbin05_00649</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CitM (TC 2.A.11) transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74605">
        <property type="protein sequence ID" value="GBC74605"/>
        <property type="gene ID" value="HRbin05_00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000802">
        <property type="entry name" value="Arsenical_pump_ArsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00758">
        <property type="entry name" value="ARSENICPUMP"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="98"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="258"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="287"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="412"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="CitMHS" evidence="10">
        <location>
            <begin position="27"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="435" mass="48055" checksum="7030281766C92BDD" modified="2018-02-28" version="1">MTAIYALLTFLLVYGLIAVRRVGRFSIPVWIPMLIGALVMLATQTISIEQAYKAVKMDVIIFLLGMFMIVAVLERAGIIQHITVSILKRTRSMDRLLFFILVVMGTLSAFLMNDTIALVATPILVGMSRFGINPKPLLIVLAFAVTIGSAMTPIGNPQNFLISVESGMKAPMLDFMKYLALPTITNYIVTYYLLRWYYRNNLKDMSVNINLYNDDHDPSKSIIYEPRMAKISIFVVSAVILGFFMVSIARAIGLEPMLDMSHIALVGGLFMLAYSRDRVAILKHMNWGIIVLFITMFVFMDALSKAGIIAMIADMLSPLQLDSDASEPTSPSTILAIVSTSTFLSQFMSNVPFVAFYLNVMHEQGFSSDDIKAWVTLAGASTLAGNLTILGAASNLIILEAARKDGFTFLEFFKIGSLVTLANMLILLTFLLVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD39</accession>
    <name>A0A2H5VD39_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000032">
        <property type="protein sequence ID" value="GBC74598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74598">
        <property type="protein sequence ID" value="GBC74598"/>
        <property type="gene ID" value="HRbin05_00642"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="164" mass="18872" checksum="DB8949D7CB8A7A0B" modified="2018-02-28" version="1">MKGEVKGENEDREEIRMEEGEEHVLQQSQPLQQEQPVVKRRRGRPRKVTVTTEEVPTTDRAAVVTEGAEVEPTVATVKPVQLPKRVIRRLTKLGDRLEIIEGMLRPLKSIEKDRSSIKDMQKQLKVIARQVTRLEKSVNKLIGKGVGRRGRRGRRGRRGRKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD40</accession>
    <name>A0A2H5VD40_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Isopentenyl-diphosphate delta-isomerase</fullName>
            <ecNumber evidence="8">5.3.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fni</name>
        <name evidence="8" type="ORF">HRbin05_00634</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homooctamer. Dimer of tetramers.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="8"/>
    <dbReference type="EMBL" id="BEHH01000031">
        <property type="protein sequence ID" value="GBC74590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74590">
        <property type="protein sequence ID" value="GBC74590"/>
        <property type="gene ID" value="HRbin05_00634"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011179">
        <property type="entry name" value="IPdP_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43665">
        <property type="entry name" value="PTHR43665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_dh" evidence="7">
        <location>
            <begin position="3"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00025810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="100" mass="11132" checksum="948AC257BD073A86" modified="2018-02-28" version="1">MSLLEVRRSVRIGIIASGGLRSGLDIAKCIALGADICALAWPFLKCAAESKESVLDYARMLIEELRAAMFLTGSRDIKALRRVRYNLQGPLLEWFSVYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD58</accession>
    <name>A0A2H5VD58_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA (Adenine(58)-N(1))-methyltransferase TrmI</fullName>
            <ecNumber evidence="5">2.1.1.220</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">trmI</name>
        <name evidence="5" type="ORF">HRbin05_00532</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.220" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000022">
        <property type="protein sequence ID" value="GBC74491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74491">
        <property type="protein sequence ID" value="GBC74491"/>
        <property type="gene ID" value="HRbin05_00532"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031515">
        <property type="term" value="C:tRNA (m1A) methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016429">
        <property type="term" value="F:tRNA (adenine-N1-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014816">
        <property type="entry name" value="tRNA_MeTrfase_Gcd14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12133">
        <property type="entry name" value="PTHR12133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08704">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017269">
        <property type="entry name" value="GCD14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51620">
        <property type="entry name" value="SAM_TRM61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="117"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017269-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="269" mass="30283" checksum="DB8E4C82E768B8CE" modified="2018-02-28" version="1">MLYSLLVRNMDDSVIGEGTYLILFHGKRSWLIRVEKGKKMHTHLGIIDIDEAIGKEYGSYIESSLGKRIYLLKPTTYDVVMKSERRTQIVYPKDMGYIASRLGIRSGMNVLEVGMGSGALTTFLASIIKPEGHVYSYEVRGEFIPIAKRNLSRLGLEPYVTIINKDASAERLEVSDVDAAVIDVGDPWKVLENVYDAMKGSAPLCAVCPTMNQLEKISSAMKGKFVDLEFTELMIRHIEAREGMTRPVFRMVGHTTYLAFGRKVMMNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD61</accession>
    <name>A0A2H5VD61_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable transcription termination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nusA</name>
        <name evidence="7" type="ORF">HRbin05_00677</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Participates in transcription termination.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000036">
        <property type="protein sequence ID" value="GBC74633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74633">
        <property type="protein sequence ID" value="GBC74633"/>
        <property type="gene ID" value="HRbin05_00677"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_A">
        <property type="entry name" value="NusA_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010212">
        <property type="entry name" value="NusA_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01952">
        <property type="entry name" value="nusA_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="KH" evidence="6">
        <location>
            <begin position="33"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="150" mass="16757" checksum="E9A35404333F8BF5" modified="2018-02-28" version="1">MTGIRLTSDELRLMSLFQSITTVTARDCVIDEKMDRVIFIIDKGDMGLAIGRNGSTIRTLQSMIGKRIELVEYADDLAEFVKNIFGREVVLDVKIGNHSSNGKVVTVIVDPRKKGMVVGREGRNVEKARLLTKRYFDVANVIIRGQEASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD86</accession>
    <name>A0A2H5VD86_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00694</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74649">
        <property type="protein sequence ID" value="GBC74649"/>
        <property type="gene ID" value="HRbin05_00694"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="79" mass="9425" checksum="589FF092290FFBDE" modified="2018-02-28" version="1">MLYSWQEHFYTRRLLVDVDTEIDSYYIALAVVDVLYHLTRLNVMGHEFGHWVMFNDISGNPNSVMYGSYNCQRWDSKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD92</accession>
    <name>A0A2H5VD92_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5-methylthioadenosine/S-adenosylhomocysteine deaminase</fullName>
            <ecNumber evidence="2">3.5.4.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mtaD</name>
        <name evidence="2" type="ORF">HRbin05_00704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.28" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000039">
        <property type="protein sequence ID" value="GBC74659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74659">
        <property type="protein sequence ID" value="GBC74659"/>
        <property type="gene ID" value="HRbin05_00704"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050270">
        <property type="term" value="F:S-adenosylhomocysteine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="75"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="426" mass="47376" checksum="07C1E1BF47D3C0A5" modified="2018-02-28" version="1">MLIRIRNISMLYGSDLEFLERASITVDDCTGLIKDVDVIVDDDNNNGSGRQSNSNYSDTSYVDADYSIDCEGLLMIPSFINAHTHIADSIAKDVTYNLGFNESIHPVFGVKSRVLSKSMSKHIMHFIRSSALAMLSKGITTFIDFREQGLNGVNMLRESMDGLAMRYLALGRVEHYSYAGDDEPLPDNAIEEALNVVGVADGFGLSGANEYSRKALEQLALIAISRGKVFGMHACESEESKAYSMERFGMSEVSRILSITRPDFLVHMTVASNDELMLAASKRIGIVVCPRANAVLGVGMPRVWDMLRFGCSVAIGTDNVMLNSPDLFREMDYLWKVSRLMYKSDKGRGIDAREIIKMVTVNPARIFRLNRLGYLAEGMYADALFIDKYSLDIMPMHNPYTAIVHRADVSSIRAVMLNGRVVHGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD94</accession>
    <name>A0A2H5VD94_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TfuA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00709</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000040">
        <property type="protein sequence ID" value="GBC74664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74664">
        <property type="protein sequence ID" value="GBC74664"/>
        <property type="gene ID" value="HRbin05_00709"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012924">
        <property type="entry name" value="TfuA_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07812">
        <property type="entry name" value="TfuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TfuA" evidence="1">
        <location>
            <begin position="58"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="227" mass="25617" checksum="E7EA9096E425B7FF" modified="2018-02-28" version="1">MHVGSDKDRSKSRIIIFLGPSLSMDKAKSILLDAEYRPPARKGDLLKVDSNTIIGLIDGVFLQDYPPTPIEVYTAIARGAKVFGAASIGALRAVELERLGMKGIGTIFRLYRQGRIEGDDEVAVTFNSNDYSLHSEALIDIRYTLYHAYKAGVISNDTRRRLVSIAKWIYFPYRTYDAIISKAREKGISSRELSALESYIQSNKRSLKEEDSIKLLRFLTKYTNNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD96</accession>
    <name>A0A2H5VD96_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">alaS_2</name>
        <name evidence="2" type="ORF">HRbin05_00684</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000037">
        <property type="protein sequence ID" value="GBC74640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74640">
        <property type="protein sequence ID" value="GBC74640"/>
        <property type="gene ID" value="HRbin05_00684"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043039">
        <property type="term" value="P:tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_SAD" evidence="1">
        <location>
            <begin position="101"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="319" mass="36228" checksum="168C1EF0BF64964B" modified="2018-02-28" version="1">MERYHDARAHTAEHIFARALQNLLGPESIQVLKVEHTDDVNRVYIRCKELSMDEVYQAMIIVNRTIEEGRTVREHTFPSLDEARRRFPDVRAYEVRITGNVRVVEIDGYDHSACIKEHVSNTRECEFFIVKSISRERDISKVEYLVGDKAKRYAIESVKRLADIAMMLRANMNTLEATLSNILEELSMLRTSIRSVTDDAVSALSAVRVRELNLYYGSFNMLDDDILIKKASTMVKDGTDNKLIIFLNRKRDRSNVVIASNDPRLDSNTLLKAIIARYGGKGGGKAEFATGYIITSLGVDVDHKIKQEVMGLIEQLLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDA7</accession>
    <name>A0A2H5VDA7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00723</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000042">
        <property type="protein sequence ID" value="GBC74677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74677">
        <property type="protein sequence ID" value="GBC74677"/>
        <property type="gene ID" value="HRbin05_00723"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="222" mass="24967" checksum="4AB4FB57463235E0" modified="2018-02-28" version="1">MLLVGHAAWAYVISRSLASVLNVKINPYLVMLLGMVPDADILLQEYIKHRSVTHSMLFWGIVFIPFFIAYRKRSIPYFMAVVQHIMLGDVIVASTNLIWPWRYEIGMGYSALSPLNMAMESIGLGLALLLTIKYDRFIITRNRCNILGLVVILPLLGSMLYLFTANGLLFLDHIIGSSISAKNMIRGSNDMMFVAMILHVSFSILLSISILQGMYALIARIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDB0</accession>
    <name>A0A2H5VDB0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative glycosyltransferase</fullName>
            <ecNumber evidence="3">2.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.-.-" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000042">
        <property type="protein sequence ID" value="GBC74679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74679">
        <property type="protein sequence ID" value="GBC74679"/>
        <property type="gene ID" value="HRbin05_00725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="23"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="317" mass="35214" checksum="C570B6285AAE256A" modified="2018-02-28" version="1">MGVEVKEGLKDRLKAMDVNKLITVVIPTLNEEQGIAKVIEELHSLGITNILVVDGYSSDRTVDVAKSLGARVIYQHGHGKTGALKAAVEHVNTPYMLVMDGDYTYDASSIERFIQHMDNYDEIIGARIPVDDASMSKLHRFGNAVITKAFNLLMNTNLSDVCSGMYMLKTDTMREIDLNTSGFDVEAEIAAQIASIGSITEVPINYRARIGRQKLSTWKHGFRIISSIFNLAKVHNPGAFYSLLVSLLLIPTGIIFFNSFLEVMYTGKFSSNWFLVGVALLLVAIQGMSIGVLSLVVKRSQMRLIRMMRRQIGKVYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDC1</accession>
    <name>A0A2H5VDC1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000044">
        <property type="protein sequence ID" value="GBC74689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74689">
        <property type="protein sequence ID" value="GBC74689"/>
        <property type="gene ID" value="HRbin05_00735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="39" mass="4412" checksum="FC20EA17CE8417FF" modified="2018-02-28" version="1">MYPSEVKAGYIVIERAGGNYVRLSSQELAELRLKLTRLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBB2</accession>
    <name>A0A2H5VBB2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Ribosome biogenesis protein Nop10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nop10</name>
        <name evidence="8" type="ORF">HRbin05_00004</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 7">Involved in ribosome biogenesis; more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the NOP10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73976">
        <property type="protein sequence ID" value="GBC73976"/>
        <property type="gene ID" value="HRbin05_00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00803">
        <property type="entry name" value="Nop10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007264">
        <property type="entry name" value="H/ACA_rnp_Nop10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036756">
        <property type="entry name" value="H/ACA_rnp_Nop10_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023532">
        <property type="entry name" value="Nop10_arc-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04135">
        <property type="entry name" value="Nop10p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144210">
        <property type="entry name" value="SSF144210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 7" id="KW-0698">rRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC73976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="60" mass="7243" checksum="151EA9F6E705DB88" modified="2018-02-28" version="1">MRHLLRRCYTCKIYTLKQECPRCHGLTHDPHPPKFSPDDRYARYRIADRYKADSGGYKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBC0</accession>
    <name>A0A2H5VBC0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cob(I)yrinic acid a,c-diamide adenosyltransferase</fullName>
            <ecNumber evidence="2">2.5.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">btuR</name>
        <name evidence="2" type="ORF">HRbin05_00006</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73978">
        <property type="protein sequence ID" value="GBC73978"/>
        <property type="gene ID" value="HRbin05_00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00561">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003724">
        <property type="entry name" value="CblAdoTrfase_CobA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02572">
        <property type="entry name" value="CobA_CobO_BtuR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015617">
        <property type="entry name" value="Adensltrnsf_CobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00708">
        <property type="entry name" value="cobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC73978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="227" mass="25397" checksum="97628064288EDCAB" modified="2018-02-28" version="1">MEQEQEQEQKQNRARVGVDGSSKRMEDSSDGKGYGEGGEEEEREKEEKKARGRRGLIIVYTGNGKGKTTAALGMAVRAVGHGMRVLMVQFIKGSWHYGEMDGALRLRPEFELITAGRGFVGIMDDNLPREAHVEAAREALRVSMEKILSGIYDIVILDEVNYAVRLGLISIEDVLELIRIKPYSTTLVLTGNYADERVLDIADLVTEMREVKHPFRKGVRALKGVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBC7</accession>
    <name>A0A2H5VBC7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cobyrinate a,c-diamide synthase</fullName>
            <ecNumber evidence="3">6.3.5.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Cobyrinic acid a,c-diamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">cbiA</name>
        <name evidence="6" type="ORF">HRbin05_00007</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2 ATP + cob(II)yrinate + 2 H2O + 2 L-glutamine = 2 ADP + cob(II)yrinate a,c diamide + 2 H(+) + 2 L-glutamate + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:26289"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="ChEBI" id="CHEBI:58894"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 10/10.</text>
    </comment>
    <comment type="domain">
        <text evidence="3">Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CobB/CbiA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.11" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73979">
        <property type="protein sequence ID" value="GBC73979"/>
        <property type="gene ID" value="HRbin05_00007"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00231"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042242">
        <property type="term" value="F:cobyrinic acid a,c-diamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00027">
        <property type="entry name" value="CobB_CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004484">
        <property type="entry name" value="CbiA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011698">
        <property type="entry name" value="GATase_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43873">
        <property type="entry name" value="PTHR43873"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07685">
        <property type="entry name" value="GATase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00379">
        <property type="entry name" value="cobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="4">
        <location>
            <begin position="13"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="GATase_3" evidence="5">
        <location>
            <begin position="259"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="site" description="Increases nucleophilicity of active site Cys" evidence="3">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC73979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="465" mass="51388" checksum="3D3EE2EEBC3839F2" modified="2018-02-28" version="1">MDIYAERHKHARVVIAGTNSGVGKTSITIGLMHALKAKGYRVQGFKVGPDYIDPSYHTSITGIPSRNLDPWLMGEDNLLESFINAMRSSNADVAVIEGVMGLYDGLSGMDDYASTAHVATLLDSPVILVIDASKAARSVAAMALGFIEFNRAVKVKGVILNNVAGDRHAKYCSDALEQKGIPVFGVVRRNKDIMLKERHLGLVPTHESRDAKDDALATARYVSEHINADGIIAVAEGAPALKHTSMEVSLSSIKDHTITVGVALDESFNFYYADNLEMLSRYARVVYFSPIKDEEPPECDGLYIGGGFPEVLAEMLARNSRMMRRIKEYAEDGMPVYAECGGLMYLSRSITDQDGSKHDMVGLVDVDTIMDRRLTLNYTEARISNPCILAEHGSMVRGHEFHYSTLVDIAKDSRFAYEMLRGKGVDGSRDGFIVHNTLASYMHLHFSRKNLVERFIASCKRYSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBD6</accession>
    <name>A0A2H5VBD6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00032</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74004">
        <property type="protein sequence ID" value="GBC74004"/>
        <property type="gene ID" value="HRbin05_00032"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="51" mass="6101" checksum="6596EBBAB415E800" modified="2018-02-28" version="1">MDGRKEAKAWIAYRWMAESAFSAFKCIFGEHVRAVRWKNMVRELKTSIYKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBE1</accession>
    <name>A0A2H5VBE1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">5,6-dimethylbenzimidazole synthase</fullName>
            <ecNumber evidence="2">1.13.11.79</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bluB</name>
        <name evidence="2" type="ORF">HRbin05_00035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.79" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74006">
        <property type="protein sequence ID" value="GBC74006"/>
        <property type="gene ID" value="HRbin05_00035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102919">
        <property type="term" value="F:5,6-dimethylbenzimidazole synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02145">
        <property type="entry name" value="BluB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012825">
        <property type="entry name" value="BluB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02476">
        <property type="entry name" value="BluB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="228" mass="26130" checksum="1E4D277D6F11E3E1" modified="2018-02-28" version="1">MIIINRPASISMDDFLPEEKRGVYKAIYSRRDVRAHFLPKEIPDDVLFRILDAAHHAPSVGFSQPWNFIIIRDKGIKARVKELFMQEFERSSSMIEDEQRRKKYLSLKLEGIMEAPVNICVTYDPNRFGPFIIGKSSIPETGLYSVCCAIQNLWLAARAEGIGVGWVSILSNDKLKEVLRIPEGIVPIAYLCLGYVTHFESIPDLERAGWLSRLPLEDVLYFEQWGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBE2</accession>
    <name>A0A2H5VBE2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribonuclease Z</fullName>
            <shortName evidence="8">RNase Z</shortName>
            <ecNumber evidence="8">3.1.26.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">tRNA 3 endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNase Z</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">rnz</name>
        <name evidence="11" type="ORF">HRbin05_00031</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="8"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74003">
        <property type="protein sequence ID" value="GBC74003"/>
        <property type="gene ID" value="HRbin05_00031"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02651">
        <property type="entry name" value="RNase_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="9">
        <location>
            <begin position="23"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="10">
        <location>
            <begin position="199"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="307" mass="34342" checksum="8D8E3615141014DE" modified="2018-02-28" version="1">MQLRIIFLGTSSAVPTAKRGLTSIAVQRGGELLIFDVGEGMQRNFLKSGLGTNRRMKVFITHMHSDHVLGLLGFMQTLALNGRDMPLYIYGPDILKEYIDVNTRLLNVNLTYDVYFTAVGEGVVVKEKEYTVKACKAEHSINSYAYCIEEHDRPGVFYPEKAIALGVSKGRLWHRLQHGEDVLVDGRLVRSSDVTGPKRKGRRIGISGDTRANERLEEFFKGCDLLVFDSTFSEDEKDRALETMHSTAREAAELASRAGVKMLVLTHFSARYDDVSKLVKEASILHNNVVAAEDMMVIDVPYPPSDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBE4</accession>
    <name>A0A2H5VBE4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HRbin05_00046</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74015">
        <property type="protein sequence ID" value="GBC74015"/>
        <property type="gene ID" value="HRbin05_00046"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027596">
        <property type="entry name" value="AmmeMemoSam_rS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016431">
        <property type="entry name" value="Pyrv-formate_lyase-activ_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004869">
        <property type="entry name" value="PflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01101">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04337">
        <property type="entry name" value="AmmeMemoSam_rS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="72"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR004869-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="356" mass="40959" checksum="BDB427F898A00B12" modified="2018-02-28" version="1">MQQVIGKEAVLYTKDKGDRVRCTACARYCSIPEGKIGLCGIRGNIGGKLYLFVYGRIIAGQIDPIEKKPVIHYHPGSMIYSIATTGCNWLCQYCQNYDISQRRKIEGIEMSPEQVVEQALYYGCEGIAYTYNQPTIFIEYARDVGVIARSKGIFNIFVSNGYDTPETVNMMKEFLDCITVDFKGSGETKFVRRYIGIPDAQPVFDTLREIRDKTSIHVEITDLIVPKVGDDLDAARRLARFVHDELGPDVPLHFLRFHPDYKMMDLPYTPVETLEKHYDIAREEGLRYVYIGNIPGHRYESTYCPECNNIVVGRFGYNITAWNLDEHNRCIFCHYPIPIIGRLSKNAYRKRFQFIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBE8</accession>
    <name>A0A2H5VBE8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00038</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74008">
        <property type="protein sequence ID" value="GBC74008"/>
        <property type="gene ID" value="HRbin05_00038"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009788">
        <property type="entry name" value="GvpD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07088">
        <property type="entry name" value="GvpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="23"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="474" mass="53907" checksum="255A9888C13B7FAC" modified="2018-02-28" version="1">MREELLDSRRRLSEIFQPFFMLRSNSLLIKGLPGTGKTTLALSLLSSMGVKGLYISTRVSYSDLINQFPWAKDVLTEESVVNMNPFDVSSKVSIVSDLRLASALTLLEKIINSSIHLKDGLIILDSFDALTQAISSEERNKILKSIIAIADANNNMIVFISEKPEDLELGYICDGIISLTYTIKNGFKLRKMNIEKLRGVKVDCPVLPFSLDDGFFHVINPLQNRCLLPTNDSKLFEPKESIEGYISTGNKQLDRILGNGIKQGSVVLLEVGDVNRQVLAYFLACIVLNALRSKRPAITISSSERPYKSILRYLQSFCTKEEINDYYTLFIFEKKSNSGDEPYLANELTDDIIDNEKVFMSKYDEIMSRHGKSPVITYDLRWREMSAKERVDELISKIIVGIRKVRSNGCVEIIINTPHMTSYEFSKQAADIHIKLVEEDGIPLFIITRPYKGIYMFLFDNSKGYPYYRLIQMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBF7</accession>
    <name>A0A2H5VBF7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredox_DsbH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74024">
        <property type="protein sequence ID" value="GBC74024"/>
        <property type="gene ID" value="HRbin05_00055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02955">
        <property type="entry name" value="SSP411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004879">
        <property type="entry name" value="DUF255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024705">
        <property type="entry name" value="Ssp411"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899">
        <property type="entry name" value="PTHR42899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03190">
        <property type="entry name" value="Thioredox_DsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006402">
        <property type="entry name" value="UCP006402_thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredox_DsbH" evidence="1">
        <location>
            <begin position="6"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="683" mass="78735" checksum="A688CE9E188E8299" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBG5</accession>
    <name>A0A2H5VBG5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00066</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74035">
        <property type="protein sequence ID" value="GBC74035"/>
        <property type="gene ID" value="HRbin05_00066"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="606" mass="70076" checksum="1FFC213E0F3C87FC" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBH7</accession>
    <name>A0A2H5VBH7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ParB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00069</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74038">
        <property type="protein sequence ID" value="GBC74038"/>
        <property type="gene ID" value="HRbin05_00069"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="1">
        <location>
            <begin position="4"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="343" mass="39554" checksum="B9A6EC4FD8EB4DD4" modified="2018-02-28" version="1">MLLVEVDVDALKSVDHIVTLSTHPMIRSIADEVKRQGSSSIQPIVVGEVDGEYYILDGYARVQACRIADVKSIRAYVIKLNSKEDAQIWHIKFNIRSTLNILKLYEAIRGKIWDEDYICSKYGMDKMMARLLQRLERIKGRAYAKLQVYMNSIVAKFNRVPPIPYYIIVLISELEDEELQEKAVDFAFINIDDDEDIFSFQDYDRMLAFIKMLRSSYRKHSASCITSSNTIEVSGKRLMSIEGKKSRGKSKDKHLYFTCSCGTSYSIDTSDYVISRVEENEHVIVLKDIEHKTLHIVPDDIVETLELDKYRARWYIVDGSEINFLTKVFNCKVAVLARDGELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBI0</accession>
    <name>A0A2H5VBI0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00076</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74045">
        <property type="protein sequence ID" value="GBC74045"/>
        <property type="gene ID" value="HRbin05_00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="83" mass="9066" checksum="149238220528AB84" modified="2018-02-28" version="1">MLGELTEEERVRWLRIVISAVIAGLIIFAAPEITAWITGISIDNPQGNIPRSLVERIGMIFMLTRYFGGAIVTIGVIAGVIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBI7</accession>
    <name>A0A2H5VBI7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00093</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74062">
        <property type="protein sequence ID" value="GBC74062"/>
        <property type="gene ID" value="HRbin05_00093"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007003">
        <property type="entry name" value="DUF655"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40734">
        <property type="entry name" value="PTHR40734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04919">
        <property type="entry name" value="DUF655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="182" mass="20926" checksum="372A98AA4BF8539C" modified="2018-02-28" version="1">MQQKKYEEYAYVLSVEPRGKSIRVKGREGIIVQAIGEERLTLLELLGTPGISIDVGERVYIGREGRTKILSVLGKLEYNELSPYAKDELPNVIESIVKNNERRFIEFINTAGPINPRIHKLELIPGIGKVIMMNILKEREMKPFESFDDLQKRTGLREPHKLIAKRILQEISGDERINLFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBJ1</accession>
    <name>A0A2H5VBJ1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00086</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74055">
        <property type="protein sequence ID" value="GBC74055"/>
        <property type="gene ID" value="HRbin05_00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="341" mass="39740" checksum="3AC6C02415278C00" modified="2018-02-28" version="1">MRFAIIGAGVAGSFLASLFNSKGHTVEVFEMYSKERHFPVCAWGTSKYMLEHFCSMVGLNFKDYILHVGNRLDIYLQNGKHDHLRLIGLITYDKRRWEQDMLKGINVNYGVRCVRDTFPVHKYDYVLDCTGFHRSMLPKPKEDLTIPVWEYMVDNLKNERDFYVIGYRNAMGYFWHFPLGNGRAFVGSGDFKKVYYGVNEFFQEEPEARILMRIGRPVRLAPPTRMDPVAYGNVVGVGESIGTVFPILGEGITPSLQSAEILYTLMVEGEYSPEAYRAMLHEKFGYYDDVYKVLRLKMEGRFSMLKHSRLLYNIYKHMKREEQRYGFEVSMDKFVNLINSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBK1</accession>
    <name>A0A2H5VBK1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74059">
        <property type="protein sequence ID" value="GBC74059"/>
        <property type="gene ID" value="HRbin05_00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="38" mass="4323" checksum="32FF428F9728B3BF" modified="2018-02-28" version="1">MSRTTTLIQFNTSEPRFSATSVILININSTYIMREDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBK6</accession>
    <name>A0A2H5VBK6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Anaerobic sulfite reductase subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">asrB</name>
        <name evidence="4" type="ORF">HRbin05_00098</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="2">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74067">
        <property type="protein sequence ID" value="GBC74067"/>
        <property type="gene ID" value="HRbin05_00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019480">
        <property type="entry name" value="Dihydroorotate_DH_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10418">
        <property type="entry name" value="DHODB_Fe-S_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1 2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="3">
        <location>
            <begin position="14"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="279" mass="31364" checksum="12ECB4C1A0AA80B4" modified="2018-02-28" version="1">MMMHDNGKSVINPYLPRIHKVKRIKRETHDTFTIEISADGFKFMPGQFNMLYAFVGEVPISISSDPADGNVIMHTVRRVGHTTSALCSLKAGDSIGVRGPFGNPWPVREQEGNDIVVVAGGLGLAPLRPLIYHLLSNRGRYGRVCLLYGAKTPRDILYRNELARWRARFDIDVYVTVDRADERWYGNVGVVTSLIPRVHVDPLHSSAFICGPEVMMRFTARELINLGFNAERIFISMERNMKCALGICGHCQFGPEFICKDGPVLSYSRIARLLSIREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBL0</accession>
    <name>A0A2H5VBL0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Protein archease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00107</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the archease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74075">
        <property type="protein sequence ID" value="GBC74075"/>
        <property type="gene ID" value="HRbin05_00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002804">
        <property type="entry name" value="Archease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023572">
        <property type="entry name" value="Archease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036820">
        <property type="entry name" value="Archease_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12682">
        <property type="entry name" value="PTHR12682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01951">
        <property type="entry name" value="Archease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69819">
        <property type="entry name" value="SSF69819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Archease" evidence="5">
        <location>
            <begin position="3"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="143" mass="16567" checksum="E5EDF5A29398C880" modified="2018-02-28" version="1">MGYRMLEHMTDALVEVEADTLEEAFALAAKALVDVMVDVSKVEERLEIMLEAYGHDLENLLYNWLEQVMIALVSDHIAMSRFNTRIEVGDYDDGRYRITAKAYGEALNLEKHNYKVEIKGVTYHMMSVENVEGKYRLRFLLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBM1</accession>
    <name>A0A2H5VBM1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L7Ae</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Ribosomal protein L8e</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rplGB</name>
        <name evidence="8" type="synonym">rpl7ae</name>
        <name evidence="10" type="ORF">HRbin05_00115</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit. Probably part of the RNase P complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the eukaryotic ribosomal protein eL8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74083">
        <property type="protein sequence ID" value="GBC74083"/>
        <property type="gene ID" value="HRbin05_00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00326">
        <property type="entry name" value="Ribosomal_L7Ae_Arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_L7Ae/L30e/S12e/Gad45"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018492">
        <property type="entry name" value="Ribosomal_L7Ae/L8/Nhp2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022481">
        <property type="entry name" value="Ribosomal_L7Ae_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000948">
        <property type="entry name" value="Ribosomal_L7Ae_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00881">
        <property type="entry name" value="L7ARS6FAMILY"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00884">
        <property type="entry name" value="RIBOSOMALHS6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03677">
        <property type="entry name" value="eL8_ribo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Ribosomal_L7Ae" evidence="9">
        <location>
            <begin position="19"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="123" mass="13667" checksum="F954076FA9D53D75" modified="2018-02-28" version="1">MSKPYYVKFEIPREMVNLIYEAVRIARQTGNVRRGTNETTKAIERGNAKLVIIAEDVEPPEVVAHLPILCEERNTPFVYVPSKKQLGEALGIDVQAAAACITDAGDARQAVEQIINTVKSMKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBM5</accession>
    <name>A0A2H5VBM5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sirohydrochlorin cobaltochelatase</fullName>
            <ecNumber evidence="3">4.99.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cbiX</name>
        <name evidence="3" type="ORF">HRbin05_00009</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.3" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73981">
        <property type="protein sequence ID" value="GBC73981"/>
        <property type="gene ID" value="HRbin05_00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016852">
        <property type="term" value="F:sirohydrochlorin cobaltochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002762">
        <property type="entry name" value="CbiX-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01903">
        <property type="entry name" value="CbiX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC73981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="257" mass="29201" checksum="49A51EFF1B4D2494" modified="2018-02-28" version="1">MRKGILIIDRGSNDPDVLIELSELCTMIRDEYMYYDHATFALLEVTSPTIEDAMLESLGYGVEHLTIVPYFLYPGLKMKVAVGKSIKVARDLGLEYTVTDCLNYHDGLIELVRARVDEAIRGIGSFNDGECDVLLIGHGSSDSDARRVFRIIGDRLRQYYRNLGICFLELDEPNIRDGIKAMLEGDPKLLILMPYFLHNGEHMKHDIREEVDSALKEFKPSCNVIMAKHLGVDRRIVKVIMDRISEAGQRSTSNIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBM7</accession>
    <name>A0A2H5VBM7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00122</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74089">
        <property type="protein sequence ID" value="GBC74089"/>
        <property type="gene ID" value="HRbin05_00122"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="134" mass="15252" checksum="D06DF21B6A44830D" modified="2018-02-28" version="1">MLSMLKHKAMRSKVWYRALSIDERVLTGLATRYIRQVRNKQLAIVLARIVIKLSIAINRFIMAEQHGFARAYAWMKGALKSGMGIFMCVMGIGGNGVYLSTSTQTPTLLIPSKSIIEWFAMLEANLMHGWRLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBN5</accession>
    <name>A0A2H5VBN5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00019</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73991">
        <property type="protein sequence ID" value="GBC73991"/>
        <property type="gene ID" value="HRbin05_00019"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC73991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="65" mass="7842" checksum="D1A812C35F0FA79C" modified="2018-02-28" version="1">MLMLANTCPECNGDLLYEVSTKHFICRNCGLYVTREQLDDIRDRLRPRRKSSKEAEYLEWWMSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBP1</accession>
    <name>A0A2H5VBP1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00139</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74106">
        <property type="protein sequence ID" value="GBC74106"/>
        <property type="gene ID" value="HRbin05_00139"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="98"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="300" mass="36034" checksum="29606E7878F9C9CA" modified="2018-02-28" version="1">MHSSKEELKKVLLNLLLEDVEFRHAVAGAIGYKEILDRIAKVDEDMNKRFLEMEEKMNKRFLEMEEKMNKRFLEMEEKMNKRFLEMEEKMNKRFLEMEERVNARFLKVEEDIKELRKDLNDLRRDMQEGFKRHDEEFAKVWKSIEDLRRDMQEGFKRHDRLIQELSISIGSLGRRTGKDMERLILNIYRDQLMQRGIDKDKAMRFEYIDKEGLYGLKGKRYEFDIIVSNSHADILEIKNRVAEDDVVTFYEKVNSIKPVIEREYGSIKRLVTVSIHIDREALTKAKELGIECIYGYMVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBQ2</accession>
    <name>A0A2H5VBQ2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="12">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">trpB</name>
        <name evidence="14" type="ORF">HRbin05_00151</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3 12">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the TrpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="12"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74118">
        <property type="protein sequence ID" value="GBC74118"/>
        <property type="gene ID" value="HRbin05_00151"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="13">
        <location>
            <begin position="56"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="GBC74118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="402" mass="44138" checksum="E0D80E4B1E436C71" modified="2018-02-28" version="1">MRLKHYPIDGKFGRFGGRYVPETLIPALEELEKAYMDARDDKDFKKDLEYYLKHYAGRPTQLYHAKNLSDAVGGAGIYLKREDLLHGGAHKINNTIGQALLAKRMGKERVIAETGAGQHGVATAMACAALGLRCEIYMGAKDAERQRLNVFRMELLGAKVNRVYSGSQTLKDAINEALRDWITNVRSTYYLLGSVVGPHPYPMMVRDFQSVIGREIRKQCISMIGGMPDAIVACVGGGSNAMGTFYEFLDSKVDLYGVEAGGHGITSKEHSATLCAGSEGVLHGMLTYLLQDEDGQIMDTHSIAAGLDYPGVGPEHAFLKSIDRVKYVSVTDDEAVDAFMKLAKYEGIIPALEAAHAVAYAMRIAREYGNDASIIITVSGRGDKDVEVVKRYLEERSSSHEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBQ3</accession>
    <name>A0A2H5VBQ3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Anthranilate synthase</fullName>
            <ecNumber evidence="4">4.1.3.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">trpE</name>
        <name evidence="9" type="ORF">HRbin05_00156</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>chorismate + L-glutamine = anthranilate + H(+) + L-glutamate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:21732"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="4.1.3.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the anthranilate synthase component I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.27" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74123">
        <property type="protein sequence ID" value="GBC74123"/>
        <property type="gene ID" value="HRbin05_00156"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004049">
        <property type="term" value="F:anthranilate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="8">
        <location>
            <begin position="20"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="7">
        <location>
            <begin position="206"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="474" mass="53800" checksum="308C3EB76A176357" modified="2018-02-28" version="1">MDTFGVTDTINVKRVNTALPPFDIFRFIHGSYENAFLLESLTGPREMAEVSIIGFEPYARVYSDMSRLYIDHLNGSKESYKLEEVDTLAYLRSILPKVKDKRFRYAGGAVGYVCYDAIRYWERLESRMLHGYPHMEFCIYKDGMVFDHINRSVYYFCIGDAREHMDLLRYLDAGGGSSATAAVVDANEYDDGQGFSSSKPIRNMSKERFISMVERAKEYIYSGDIYQVVLSKRFEFRVKGHPIPFYSMLRSINPSPYMYYLKVGERCIVGSSPEMLVRVTGNLVETFPIAGTRRIVEGDEQENTRLRDEMLRDEKELAEHTMLVDLARNDLGRVCRWGTVKVDELMVVKRFSHVQHMVSHVTGMLRDDCDAYEAFRAVFPAGTVSGAPKVRAMEIIDELEPTARGPYAGAVGYFSSNGNCDFAIAIRSMFISNGRAYVQSGAGIVADSRAENEWAETEHKANALLEALRRVNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBR9</accession>
    <name>A0A2H5VBR9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Denitrification regulatory protein NirQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nirQ</name>
        <name evidence="3" type="ORF">HRbin05_00167</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CbbQ/NirQ/NorQ/GpvN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74134">
        <property type="protein sequence ID" value="GBC74134"/>
        <property type="gene ID" value="HRbin05_00167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013615">
        <property type="entry name" value="CbbQ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08406">
        <property type="entry name" value="CbbQ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="25"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="268" mass="30296" checksum="CD6977378C99AC05" modified="2018-02-28" version="1">MLSQVEPVYIDWNNSLEILNKAYDAGIFVLIIGAKGTGKTTLVRKFAHMRSKELYTINFSLRTRESHLIGMQTIHNGNVEFVEGLLIKSMKNGSILYLDELNAAEADVLLRLDEALDDRRQIVLKEAGGQIIKARDDWFVIATINPLSHMGTKELPPQLLSRFPVRIRMEYPPAETEMKIIGAHVQLSSKDEEIVRRAIKLANTLREAASVEELYYSPSIRESIAFAKLIKQGVAPKLAAEAVFANVYEQWGETEYRKVMDLITSLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBS3</accession>
    <name>A0A2H5VBS3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00171</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74138">
        <property type="protein sequence ID" value="GBC74138"/>
        <property type="gene ID" value="HRbin05_00171"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd13946">
        <property type="entry name" value="LysW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005906">
        <property type="entry name" value="LysW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40393">
        <property type="entry name" value="PTHR40393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="57" mass="6242" checksum="11304009D534501F" modified="2018-02-28" version="1">MIKVRCLECEADLKVPSDAIEGEILTCPDCGASYELERQGEGFNIKPAQVVGEDWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBS5</accession>
    <name>A0A2H5VBS5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-glycero-alpha-D-manno-heptose 1-phosphate guanylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.71</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hddC</name>
        <name evidence="2" type="ORF">HRbin05_00176</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.71" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74143">
        <property type="protein sequence ID" value="GBC74143"/>
        <property type="gene ID" value="HRbin05_00176"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="226" mass="25625" checksum="C0CBBA0E8335036B" modified="2018-02-28" version="1">MKAIILAGGFGKRLKPLTDDRPKPMVEVLEKPIVAWQIEWLKLNGIDELILCVGYMRERIMDYLGNGSRYSVSIDYVVEDEPLGTGGAIKNAKPLLNGEERFIVVNGDIITDLNIARMVMMQNNSIAVVPLPSPYGIVEMGSDSRITGFREKPKLDQFWINAGVYCLNHDVLAYLPDKGSIEYDTFPQLASKGMLYAVKYKDVYWRSIDTHKDVEEASKELKEYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBS8</accession>
    <name>A0A2H5VBS8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00177</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74144">
        <property type="protein sequence ID" value="GBC74144"/>
        <property type="gene ID" value="HRbin05_00177"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="39" mass="4746" checksum="5F9D6CC57BB33F8E" modified="2018-02-28" version="1">MPICPICKREVKRMLSCEHTNDEEMCVECYQEIHFRLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBT4</accession>
    <name>A0A2H5VBT4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00072</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74041">
        <property type="protein sequence ID" value="GBC74041"/>
        <property type="gene ID" value="HRbin05_00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="664"/>
            <end position="683"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="689" mass="79870" checksum="A48928F220FD5A0E" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBT5</accession>
    <name>A0A2H5VBT5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74153">
        <property type="protein sequence ID" value="GBC74153"/>
        <property type="gene ID" value="HRbin05_00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="84" mass="9047" checksum="04BF8BFAB6221C3D" modified="2018-02-28" version="1">MGMGHARYVFALTMMSFSMAIVLAISAIIIDYYILGKSSSVKVDIREATDDLIKGNVLKSIINELSKIAGSDVGKSNGEYIVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBT6</accession>
    <name>A0A2H5VBT6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent dethiobiotin synthetase BioD</fullName>
            <ecNumber evidence="5">6.3.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DTB synthetase</fullName>
            <shortName evidence="5">DTBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Dethiobiotin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bioD1</name>
        <name evidence="5" type="synonym">bioD</name>
        <name evidence="6" type="ORF">HRbin05_00180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(7R,8S)-7,8-diammoniononanoate + ATP + CO2 = (4R,5S)-dethiobiotin + ADP + 3 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the dethiobiotin synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74147">
        <property type="protein sequence ID" value="GBC74147"/>
        <property type="gene ID" value="HRbin05_00180"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43210">
        <property type="entry name" value="PTHR43210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006755">
        <property type="entry name" value="DTB_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00347">
        <property type="entry name" value="bioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="30"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="133"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="193"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="222"/>
            <end position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="246" mass="26822" checksum="98E57A7685969A1A" modified="2018-02-28" version="1">MDIGTSISIDDDGWSNGSGGGVFVTGTDTGVGKTLVTAAIVHALRSDGIDAVGMKPIATGIDRDAVFKSTDAEIIAKYSCLSTEEHELVNPVFLALEAAPYMASIVLKQDVDIERVFKAYKRLKERHEFIVVEGIGGVMVPIKKDYYVLDLIRDLELPALIVARARLGTINHTLLTVEACKRRGVEVIGIIMNMIDHSSIVEVNAGSIIQELSRVPVIGSIPYIKEMGVDDIPYIAKYIRYDLMLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBU1</accession>
    <name>A0A2H5VBU1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00193</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74159">
        <property type="protein sequence ID" value="GBC74159"/>
        <property type="gene ID" value="HRbin05_00193"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="45" mass="5357" checksum="B67918D4786C6C11" modified="2018-02-28" version="1">MLRSTSLLDTCLERRNLCIIILINARRFIGKPFREATREEDIEHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBU2</accession>
    <name>A0A2H5VBU2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00163</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74130">
        <property type="protein sequence ID" value="GBC74130"/>
        <property type="gene ID" value="HRbin05_00163"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009563">
        <property type="entry name" value="SSSCA1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06677">
        <property type="entry name" value="Auto_anti-p27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="128" mass="14579" checksum="B42AAF4D8CE5AB99" modified="2018-02-28" version="1">MKAAAEMLRKGGTLVKEACSKCRGVQVKYSGRLICINCGSETVLEEAKVGSLQDLRSVIIAKVNSTARMLEQENDIARQMEIARLLLYYLEILAKVSEEKGKEEREEEEEGKRGERKEVKEREEKEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBU7</accession>
    <name>A0A2H5VBU7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="4">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">ImGP synthase subunit HisF</fullName>
            <shortName evidence="4">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">hisF</name>
        <name evidence="6" type="ORF">HRbin05_00206</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74172">
        <property type="protein sequence ID" value="GBC74172"/>
        <property type="gene ID" value="HRbin05_00206"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="259" mass="27959" checksum="7D72E36D87BDE5D0" modified="2018-02-28" version="1">MILLAKRIIPCLDVDKGRVVKGIHFKDIRDAGNPVELAKHYSSDCADELVFLDITASEEHRATMVEVVKSVARAIDIPFTVGGGIRSMDDARAILLAGADKVSVNTAAVKNPSLITELKDVFGKQCVVVAIDAKRSMRDGEKIFYEVYIYGGKRPTGMDAVEWARRAESLGAGELLLTSIDKDGTKDGYDLELTAQVCKAVNIPVIASGGAGGPEHMLALFRETGADAALAASIFHYGGYTVRDVKRYLKDNGVEVRIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBW9</accession>
    <name>A0A2H5VBW9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="3">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 8" type="primary">panB</name>
        <name evidence="8" type="ORF">HRbin05_00226</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3 6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PanB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74192">
        <property type="protein sequence ID" value="GBC74192"/>
        <property type="gene ID" value="HRbin05_00226"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Alpha-ketoisovalerate binding" evidence="3 5">
        <location>
            <begin position="45"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="283"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 6">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5 6">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 6">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="306" mass="33696" checksum="B11B2D62801E2587" modified="2018-02-28" version="1">MGSKITVESIMGMKGKKKIVAVTAYDYTTARICDRVGVDIILVGDSAAMVMLGYKSTTPISMEEMLVFCKAVSRAREHAMVVADMPFMSYQISMEDALYNACRFIKEGNADAVKVEGGREFKHVVEAIVDAGIPVMGHIGLKPQTAPLWHGYKVQGKVVDDASRLIEDAVAIEEAGAFSIVLEQVTYEVAEMISSRLSIPTIGIGSGSSCDGQVLVLHDMLGLYEYSPRFVKRYADLSSIIAEALTRYRDDVLNARFPGEEHTFHMDAKEYERLKATSIAMDAMRSERKNQEQKGGGERGEESINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBY3</accession>
    <name>A0A2H5VBY3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribonuclease</fullName>
            <ecNumber evidence="3">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00232</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74198">
        <property type="protein sequence ID" value="GBC74198"/>
        <property type="gene ID" value="HRbin05_00232"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019975">
        <property type="entry name" value="aCPSF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033769">
        <property type="entry name" value="KH_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17214">
        <property type="entry name" value="KH_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03675">
        <property type="entry name" value="arCOG00543"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="232"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="2">
        <location>
            <begin position="461"/>
            <end position="585"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="676" mass="75386" checksum="0B22877A8BFD1EA3" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBY9</accession>
    <name>A0A2H5VBY9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="3">HMG-CoA reductase</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mvaA</name>
        <name evidence="4" type="ORF">HRbin05_00214</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74180">
        <property type="protein sequence ID" value="GBC74180"/>
        <property type="gene ID" value="HRbin05_00214"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00644">
        <property type="entry name" value="HMG-CoA_reductase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004553">
        <property type="entry name" value="HMG_CoA_Rdtase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="PTHR10572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="SSF55035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="SSF56542"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00532">
        <property type="entry name" value="HMG_CoA_R_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="420" mass="45463" checksum="7B114A5B665E4D0C" modified="2018-02-28" version="1">MRFYELDREGRLAVLKDHASLTDEDVEILREGSGIDFKMADSMIENAVSFISYPLGIATHFLINGKEYLVPMAIEEPSVVAAASKGAKVARLRGGFTAHADPSIMIGQVQVKGIKDLGRAVEDVMKSKDELLSIANSKSSLARRNAGARDLRCRVIDTASRGKMLIVELLVDVKDAMGANVINTMCESIAPRIESITNGRVLLRILSNYATHRLVRATARFAREEVGDDAVEGILDAYAFAEADVYRCVTHNKGVMNGIIAVALATAQDTRAIEAGAHAYACRDGRYSSLTHWSRDSNGDLVGSIELPLAVGTVGGLTSTHPIARLSLKILRVESARELACVMASVGLAQNFSALYALVREGIQAGHMRLHARKVAMLAGAEGNMLDEVAERLAREGNITVEHARQIMQEITHDISDGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBZ5</accession>
    <name>A0A2H5VBZ5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00242</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74207">
        <property type="protein sequence ID" value="GBC74207"/>
        <property type="gene ID" value="HRbin05_00242"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010708">
        <property type="entry name" value="5'(3')-deoxyribonucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06941">
        <property type="entry name" value="NT5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="186" mass="21694" checksum="F64B996585B45818" modified="2018-02-28" version="1">MRIAVDVDGVLADIISVWLTYYNRKHNSSLSKEQVQRWDFWKSIGYSAERFYTELAACWKEWLKVPVIESDIANSIAMLRSLGKVDIVSAQIAKDYVKRWLEHNNIVYDEYVSVARGVDKADLAYDVFIDDSPINAERISAMGRLVLLYDQPWNRHLSNGRYIVRVKNMDGVKRVLMDRLMSMKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBZ8</accession>
    <name>A0A2H5VBZ8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74215">
        <property type="protein sequence ID" value="GBC74215"/>
        <property type="gene ID" value="HRbin05_00250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="54" mass="6374" checksum="EB51C448A6EDB1E1" modified="2018-02-28" version="1">MCRCPKVHFYEVEFKLDGLRSVAYHKNCGDPLSDAQMQEFDKQLIKLWGLEVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC14</accession>
    <name>A0A2H5VC14_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">L-alanine exporter AlaE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">alaE</name>
        <name evidence="6" type="ORF">HRbin05_00262</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74227">
        <property type="protein sequence ID" value="GBC74227"/>
        <property type="gene ID" value="HRbin05_00262"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034639">
        <property type="term" value="F:L-amino acid efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010574">
        <property type="entry name" value="Ala_export_AlaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06610">
        <property type="entry name" value="AlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="73" mass="8538" checksum="A7AAB2BAEA743456" modified="2018-02-28" version="1">MVKEYRKRYIIDSLASIVFWVPIYIVFNLFVLRLELWQVLALASFSAVVNFAFGGLFGRFLDAWRRLLKVHGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC20</accession>
    <name>A0A2H5VC20_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00245</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74210">
        <property type="protein sequence ID" value="GBC74210"/>
        <property type="gene ID" value="HRbin05_00245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007052">
        <property type="entry name" value="CS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51203">
        <property type="entry name" value="CS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="99"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="CS" evidence="5">
        <location>
            <begin position="104"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="17"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="195" mass="22882" checksum="6DB70AACCBE90D53" modified="2018-02-28" version="1">MSWEEWFSRRRRPFAFWQEIEEMMREMEREMERMFERSMKELEEMVPKDLVREYKLPDGRVRREWGPFVYGYSLTIGPDGKPVIREFGNVRPSLTGGRIALKEEREPLVDVMSTDGELKVIVELPGINKEDIRVTATEKSVNIRAENPERKYSKSIDLPEEVDPASAKSTYKNGILEITFKKKGSKQEGFTIKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC27</accession>
    <name>A0A2H5VC27_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74245">
        <property type="protein sequence ID" value="GBC74245"/>
        <property type="gene ID" value="HRbin05_00280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="58" mass="6348" checksum="A55BF2CB92A5722C" modified="2018-02-28" version="1">MLDQLIVRADFNNGVTLVTTLNITFQVIPESMVGAVAPVAAGLAAFIGYRYYSRKSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC35</accession>
    <name>A0A2H5VC35_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00291</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74256">
        <property type="protein sequence ID" value="GBC74256"/>
        <property type="gene ID" value="HRbin05_00291"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="110" mass="12054" checksum="5C1C9ABF639E1B09" modified="2018-02-28" version="1">MHDEGNVIMEEDCSEDKLGAGYLVLTDKSLVFYTGKAKVLTFSKDMKKALEVPLQDVKGTRTEGFIIKKLVVELKDGRVYKFGVLNNKKWKESIDGARAGTGIGAGVGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC41</accession>
    <name>A0A2H5VC41_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00297</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74262">
        <property type="protein sequence ID" value="GBC74262"/>
        <property type="gene ID" value="HRbin05_00297"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="135" mass="15288" checksum="DA1D936E6FCBC36A" modified="2018-02-28" version="1">MDNSREKVGRDDVKASLWVFHEQIMHEDESVKESWIVIVERSRYSLFGFKVVQHESSMYPGYPGYVVSSITALDSLTAAAEMERLQGMHGIKHVRVEISDEEADSWYSMLANLSDITRSVLNPAKDMLEGVAALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC46</accession>
    <name>A0A2H5VC46_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00293</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74258">
        <property type="protein sequence ID" value="GBC74258"/>
        <property type="gene ID" value="HRbin05_00293"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013646">
        <property type="entry name" value="MMR_HSR1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08438">
        <property type="entry name" value="MMR_HSR1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGS" evidence="1">
        <location>
            <begin position="151"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="230" mass="25686" checksum="311B9E3D78B8599F" modified="2018-02-28" version="1">MEHILANRLSGLAIGEHVIADTLNELKGKRFSEWDESDMLRFARALRMKAKPIVIAANKADMHTAKPNIERIRATGRMVVPCIAEAELLLRRAASKGMIEYIPGDGTFKVKDGSLTIEQRRALEKVRMLMEEYGSTGVQRAINTAVIDALHMITVYPVEDEHNLTDKDGNVLPDAFLLKQGSTPKDLAMSVHSDLAKNFLYAIDARSKQRLGAEYRLSDRDIIKIVSASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC50</accession>
    <name>A0A2H5VC50_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribonuclease</fullName>
            <ecNumber evidence="8">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rnhB</name>
        <name evidence="10" type="ORF">HRbin05_00275</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RNase HII family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="8"/>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74240">
        <property type="protein sequence ID" value="GBC74240"/>
        <property type="gene ID" value="HRbin05_00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004649">
        <property type="entry name" value="RNase_H2_suA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00729">
        <property type="entry name" value="TIGR00729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="9">
        <location>
            <begin position="6"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="254" mass="27940" checksum="D3A0B5D00688A28E" modified="2018-02-28" version="1">MLNRIAGVDEAGRGAVIGPLVVAAVAIDASSVDRLIELGVKDSKMLDRRSRMILYSKILELCSTAVCIAEPRVIDAYVYEHALNVLEARMFAIALSKLKPLLAYVDACDTKPERFSAMIARMLDDEDIGMMISAAHKADRDNVLVGAASIVAKVTRDSVVDGVKRRYGDFGSGYPSDGRTRRFIRYLFTSGVAEDESGTSDSSRSKSHSNLISIDVSDIKLHHFHDDSMDDNGSSRFSFIRYSWKPIRSLLASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC53</accession>
    <name>A0A2H5VC53_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">26 kDa periplasmic immunogenic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00299</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74264">
        <property type="protein sequence ID" value="GBC74264"/>
        <property type="gene ID" value="HRbin05_00299"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="277" mass="29928" checksum="C4B256146CBA5A1A" modified="2018-02-28" version="1">MVRDVAMASRIISKKVMGVAGAGIVAFTLLLAFLAVEHTTMVNVRAEEQSNGKDVVERIELSVIGNAIQNIKPDKASISVGVEVQEKTAGDAARRNAELMNSVIEAVKALGIKEEQISTNYYSIYPVYEHRSKAEVCITIYPPPPECQEQVLVGYKAVNSITITMDVNVQNIGSVIDAAVNAGANQVYGVSFFISQERLDAVKASLLDKATKDARVKADSVANALNMKVVGVKSVNIMDGYYYPTPMYAREAPATTPIIPPSEQSVSASVQVVFWLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC56</accession>
    <name>A0A2H5VC56_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoribosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00303</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74268">
        <property type="protein sequence ID" value="GBC74268"/>
        <property type="gene ID" value="HRbin05_00303"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DLH" evidence="1">
        <location>
            <begin position="59"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="229" mass="25276" checksum="0444C81639E933B4" modified="2018-02-28" version="1">MKARSIKIDVSSVEEGKGRFIEGDLTISSLKECMVVFAHGSGSSRFSPRNRFVAGVLQSAGLSTLLLDLLTKEEDAIDSLTGRYRFDVELLASRLVDSVIWLEREYIDRSSSSSSSNLRIGYFGSSTGAAAALIAYARYPNNVRAIVSRGGRVDLAAHYLPGIKVPTLLIVGGHDTPVLKLNREAMDRFPRECMVRLEVISNATHLFEEQGALEQVAEKAKDWFLTHLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC65</accession>
    <name>A0A2H5VC65_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Enolase</fullName>
            <ecNumber evidence="5">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 10" type="primary">eno</name>
        <name evidence="10" type="ORF">HRbin05_00314</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cell surface</location>
        </subcellularLocation>
        <text evidence="5">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74277">
        <property type="protein sequence ID" value="GBC74277"/>
        <property type="gene ID" value="HRbin05_00314"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="4 5 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="9">
        <location>
            <begin position="5"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="8">
        <location>
            <begin position="135"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5 7">
        <location>
            <begin position="361"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5 6">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="5">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="385"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="416" mass="45572" checksum="173BD4C58A68BCFC" modified="2018-02-28" version="1">MEASITAIKARLCYNSRGQESIEVDVVTEGKYMGRASAPSGASKGRYEAVGFPNNSVEDALKVFNENKNRFIGVDASDPKAIYDVLRGIDGTPNYSIVGGSVAYAVSMAAVDSASKALNEPIFRLISIDRRKEKGYRLPYPLGNVLGGGAHAGPSTPDIQEYLVVPIGAKNMVEAVRMNVRVHRVLRDVLERKDRYFTYGRGDEGAWAPRASNMEALEAVEQACIEAGYSIGKDVALGIDFASSSLWDGNGYVYARYGNRMSKEEQIEFVSNLIRDYRLIYVEDPLHEEDFSGMAELTKRFSSIYITGDDLLVTNVSRLRVALEYKACNSAILKVNQAGSLYEALLFAREADEHGIRLVTSHRSGESIDAHIAHVAVATGSKMIKAGVVGGERVAKMNELIRLEELDMVDGMTTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC84</accession>
    <name>A0A2H5VC84_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpmC</name>
        <name evidence="4" type="synonym">rpl29</name>
        <name evidence="6" type="ORF">HRbin05_00335</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74297">
        <property type="protein sequence ID" value="GBC74297"/>
        <property type="gene ID" value="HRbin05_00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="86" mass="9448" checksum="01D38268766AAF7D" modified="2018-02-28" version="1">MARLKLKDLKALSDDDLKAKLSELRSELAKIMVDRAKGTIKKESGKVKYMRRDIARILTILGERSRRGAEGNGKDKGKGKGSSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCB0</accession>
    <name>A0A2H5VCB0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">30S ribosomal protein S19P</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsS</name>
        <name evidence="5" type="synonym">rps19p</name>
        <name evidence="7" type="ORF">HRbin05_00338</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74300">
        <property type="protein sequence ID" value="GBC74300"/>
        <property type="gene ID" value="HRbin05_00338"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005713">
        <property type="entry name" value="Ribosomal_S19A/S15e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01025">
        <property type="entry name" value="uS19_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="135" mass="15315" checksum="F9DC9890E763FED1" modified="2018-02-28" version="1">MDADMVKEFRYRGRTLQELQEMSMEELINILPSRIRRTLKRGLGEERLKLLRELKAAKDNPSGKPVKTHLRDMPILPNMVGLTIHIANGKEFVPVEIKPEMIGHYLGEYAITNKPVKHGTPGIGASRSSLYVPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCC3</accession>
    <name>A0A2H5VCC3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cheY</name>
        <name evidence="2" type="ORF">HRbin05_00376</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74338">
        <property type="protein sequence ID" value="GBC74338"/>
        <property type="gene ID" value="HRbin05_00376"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="1">
        <location>
            <begin position="8"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="126" mass="14342" checksum="FF5E0A027757FCE8" modified="2018-02-28" version="1">MVPKNLIKILVVDDAAFMRLVLKDILKNLGYTNIIEASDGFMAIEQYKKFKPDLVTMDVNMPKMDGVQALKQIIKINPMAKIIMVTAVEQRYIVQEAIRNGAKDYIVKPFDRAMVGTVIERVLNTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCC9</accession>
    <name>A0A2H5VCC9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15 16" type="primary">ilvD</name>
        <name evidence="16" type="ORF">HRbin05_00266</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74231">
        <property type="protein sequence ID" value="GBC74231"/>
        <property type="gene ID" value="HRbin05_00266"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="469"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="GBC74231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="558" mass="59788" checksum="803688CFF81EA4CF" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCD5</accession>
    <name>A0A2H5VCD5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00388</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74348">
        <property type="protein sequence ID" value="GBC74348"/>
        <property type="gene ID" value="HRbin05_00388"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_11" evidence="2">
        <location>
            <begin position="12"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="1">
        <location>
            <begin position="83"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="324" mass="36965" checksum="CD54ADBA713FE502" modified="2018-02-28" version="1">MPKRYSIEEVKQRIIDVLRQSDSGLSGIEIAERTGINRVTITKYLNILETMGIIRRRSMGPVNLWYIQYGMDLSSKDILELQQVYMDALFTYDEDRARTILLNAIHSNIDPILLMSDVVIPTVNTAGELYARGRMSTMDLMLINNLAMESLDLIKFNASRVEVKKDAYAVFISMSEKGSRREAIDMKAASIAFYIKGWRPFLLGNVASEAGLFLDIDMVRFINRIWRDKEKGIILLYISAAEEFSTLNELIRSVKEKLEKSILVIVGGRVVDRLEGKDKEKGSDTDTGVGVGVKDTAYPYIDYYAMDIMKAVEWGERMYRSLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCE9</accession>
    <name>A0A2H5VCE9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cheA</name>
        <name evidence="8" type="ORF">HRbin05_00378</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74340">
        <property type="protein sequence ID" value="GBC74340"/>
        <property type="gene ID" value="HRbin05_00378"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPt" evidence="7">
        <location>
            <begin position="3"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="198"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="6">
        <location>
            <begin position="410"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="3">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="559" mass="61698" checksum="FAEC3C399A5DC3CD" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCG8</accession>
    <name>A0A2H5VCG8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycine cleavage system H protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gcvH</name>
        <name evidence="2" type="ORF">HRbin05_00400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74360">
        <property type="protein sequence ID" value="GBC74360"/>
        <property type="gene ID" value="HRbin05_00400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="1">
        <location>
            <begin position="51"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="250" mass="28447" checksum="FDFBB70D90708610" modified="2018-02-28" version="1">MGRIENCEFDDTLLYDTENLVWLKVEYPSSTPSSQWEGREEGDTITGRKTLVKIGITSILAYIAGRLTSVKIRPEGTEVEKGKSIASIESLRYFGVVRSPVRGRMVKINKLAVGKPKIVNDNPYGEGWIAVLEVSDAKDLDQLEPLEKCKHKLAEKIREMHVRCFSAFPDHEMVEIGVECAAVIPKLDELIARIEKGEVVHIVSDDPTADIEIVRWSEERGHELLEIRREEQLIHMLVRKSDGIRFIRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCH5</accession>
    <name>A0A2H5VCH5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74396">
        <property type="protein sequence ID" value="GBC74396"/>
        <property type="gene ID" value="HRbin05_00436"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="170" mass="19258" checksum="28EA5C93A2381829" modified="2018-02-28" version="1">MVFNRNVHDARDKVVSAVSHLELELKSITSLYNKLQRDLELRTLGYTCSCNSNNNICSSNSSSSSSGASLDTPCNDDITALLTLMKTTQLALQSITIRIDTLIYIQELLMLLERTMNVLNSIRSDIKRMEQEMQSIMQKIGTSFIESKIEFGYSERIELPSIDGYDAYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCJ3</accession>
    <name>A0A2H5VCJ3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00447</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74407">
        <property type="protein sequence ID" value="GBC74407"/>
        <property type="gene ID" value="HRbin05_00447"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="134" mass="15921" checksum="67207083EAF97D8B" modified="2018-02-28" version="1">MTILMDKAVNSYKDLLTFLRAKLGSLYDEIYPVLNAYLESKKVRKKVNLDELDGDIDRLMELIVNPVVHKIVRENAPDFSWIPVVGNDLSRKVREELHRKTEEGIRQARYYLKKDKRLRENLQLFLQDVVDRYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCJ9</accession>
    <name>A0A2H5VCJ9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L39e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl39e</name>
        <name evidence="7" type="ORF">HRbin05_00455</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eL39 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74415">
        <property type="protein sequence ID" value="GBC74415"/>
        <property type="gene ID" value="HRbin05_00455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1620.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00629">
        <property type="entry name" value="Ribosomal_L39e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000077">
        <property type="entry name" value="Ribosomal_L39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020083">
        <property type="entry name" value="Ribosomal_L39_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023626">
        <property type="entry name" value="Ribosomal_L39e_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00832">
        <property type="entry name" value="Ribosomal_L39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48662">
        <property type="entry name" value="SSF48662"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00051">
        <property type="entry name" value="RIBOSOMAL_L39E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="52" mass="6307" checksum="01960BF4F06A7134" modified="2018-02-28" version="1">MGSRKTKPRKNRLMKKTKQNSPVPLWVILKTNRRVRRNPQQRHWRRSSVDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCK7</accession>
    <name>A0A2H5VCK7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt-factor III methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.272</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00473</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.272" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74433">
        <property type="protein sequence ID" value="GBC74433"/>
        <property type="gene ID" value="HRbin05_00473"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11646">
        <property type="entry name" value="Precorrin_3B_C17_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006363">
        <property type="entry name" value="Cbl_synth_CobJ/CibH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01466">
        <property type="entry name" value="cobJ_cbiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="5">
        <location>
            <begin position="12"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="266" mass="29463" checksum="BB8A2395FFD688C3" modified="2018-02-28" version="1">MVGSNGNSSIGKLYIVGIGPGYEEHMTFRAKQCIMDSNIVIGYETYIDLIRHMLDGKEVYAYAMTQEVDRANHAIDLASKGNIVSLVSSGDPGIYGMAGLVYEVLAERDWDGMNPYVEVVPGVSALNACAALVGSPLMADFAVVSMSDLLVPWDIIVKRVEAAAQGDFVIVIYNPQSKKRVHQLRDTRDILLKYRSARTPVAIVKSAYRDSQSIVLTDLEHMLEYQDHLGMLSTIIIGNSSTFIYKGLMINPRGYKSKYELVREQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCL0</accession>
    <name>A0A2H5VCL0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L31e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl31e</name>
        <name evidence="7" type="ORF">HRbin05_00454</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL31 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the ribosomal protein L31e family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74414">
        <property type="protein sequence ID" value="GBC74414"/>
        <property type="gene ID" value="HRbin05_00454"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00463">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00410">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000054">
        <property type="entry name" value="Ribosomal_L31e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020052">
        <property type="entry name" value="Ribosomal_L31e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023621">
        <property type="entry name" value="Ribosomal_L31e_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10956">
        <property type="entry name" value="PTHR10956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01198">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01380">
        <property type="entry name" value="Ribosomal_L31e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54575">
        <property type="entry name" value="SSF54575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01144">
        <property type="entry name" value="RIBOSOMAL_L31E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="85"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00410"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="120" mass="13672" checksum="0E88FCA3499FF574" modified="2018-02-28" version="1">MSREEGVEERVYTINLSKVVLAPDNRRSKRAINMIREFAIRHMKSEEVIIDEELNELVWARGIRSPPRRIRVIISKDASGIVTVKPYKQEEEGKSVEERSKEKEGSSSNATDAKSSKTEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCL1</accession>
    <name>A0A2H5VCL1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74428">
        <property type="protein sequence ID" value="GBC74428"/>
        <property type="gene ID" value="HRbin05_00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="195" mass="22041" checksum="DD1EDB703A0B68D8" modified="2018-02-28" version="1">MQPRSDETDDNYAKEYRKSVLVYKIIFYVCAAIMLSITVYALAESLREYLASGSVVIGEVLVNTEVPFKGFAKLVTYLMISSVVGWYCVTKIGREKTRNISARNRAILKLIALAIAVVALYELVYNFVVWNALMTADAISGIIRIDVLNIPYPNPKTPWSLVFATKMFLAAFVISAHAFYLMARDERRAFDRLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCL3</accession>
    <name>A0A2H5VCL3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphomethylpyrimidine synthase</fullName>
            <ecNumber evidence="2">4.1.99.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">thiC</name>
        <name evidence="2" type="ORF">HRbin05_00440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.17" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74400">
        <property type="protein sequence ID" value="GBC74400"/>
        <property type="gene ID" value="HRbin05_00440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002817">
        <property type="entry name" value="ThiC/BzaA/B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01964">
        <property type="entry name" value="ThiC_Rad_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="85" mass="9509" checksum="5075B8177B48C978" modified="2018-02-28" version="1">MTRARRMLDWAKQISLAIDPEEAARIHNRDGQLQGNSVPCTMCGSACVYIMLPQQRRYEVAEGEGEGGGEKEKEEEDVIVKGKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCM5</accession>
    <name>A0A2H5VCM5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Na(+)/H(+)-K(+) antiporter GerN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">gerN_2</name>
        <name evidence="6" type="ORF">HRbin05_00485</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74445">
        <property type="protein sequence ID" value="GBC74445"/>
        <property type="gene ID" value="HRbin05_00485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="279"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="9"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="368" mass="39905" checksum="B5747677932B92AB" modified="2018-02-28" version="1">MVDLYSSALIASAIVVSGIVSSRAKISSSIIEVTLGIILANVLLLKIEGWLDFIATFGGLTLTFLAGVEVESRLLRSKARVSSVIGTLAFLAPLIGELSFLTLYTDWSWNAKLAASLALTTTSIAVVYAVLTEYGIMRTQFAKTIVAITFVNDILTIVGISLIEPAFNITTIAFLLTLAILALIVPRLTNLLIARYGEKVVEVELRFIFAMLLLVSFFADEAGMHAIFGAFMLGLIFANTLQRHDRVLAKMKTVTFTLLSPAFFIRAGMLISINAVTQNILIVLMLLLVKILSKFAGCYMLCKRWLPDAPTFSTLLLSTGLTVGTITATIGRDLGFLTQEQFSITVIAVILSAVVPTIIAKRFVPKNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCP1</accession>
    <name>A0A2H5VCP1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L19e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl19e</name>
        <name evidence="7" type="ORF">HRbin05_00507</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74466">
        <property type="protein sequence ID" value="GBC74466"/>
        <property type="gene ID" value="HRbin05_00507"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022625">
        <property type="term" value="C:cytosolic large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01475">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035970">
        <property type="entry name" value="60S_ribosomal_L19/L19e_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000196">
        <property type="entry name" value="Ribosomal_L19/L19e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015972">
        <property type="entry name" value="Ribosomal_L19/L19e_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039547">
        <property type="entry name" value="RPL19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10722">
        <property type="entry name" value="PTHR10722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01280">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01416">
        <property type="entry name" value="Ribosomal_L19e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48140">
        <property type="entry name" value="SSF48140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L19e" evidence="6">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="57"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="148" mass="17143" checksum="F359B1E8A5005EE3" modified="2018-02-28" version="1">MNLKNKRKLAARALGVGANRIKFDPNYLEDVEDAITRADMRSLLTARTILIKSIKGTSRGRARIKHAKEKKRGKGKGSKEGKKSARQGKKELWVTKVRAYRRYLKVLKDRKEISNKVFWSLYRRIKGGQVRSLAHLRSLVEEEKRKQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCQ2</accession>
    <name>A0A2H5VCQ2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L32e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl32e</name>
        <name evidence="6" type="ORF">HRbin05_00508</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74467">
        <property type="protein sequence ID" value="GBC74467"/>
        <property type="gene ID" value="HRbin05_00508"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00513">
        <property type="entry name" value="Ribosomal_L32_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00810">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001515">
        <property type="entry name" value="Ribosomal_L32e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023654">
        <property type="entry name" value="Ribosomal_L32e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018263">
        <property type="entry name" value="Ribosomal_L32e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036351">
        <property type="entry name" value="Ribosomal_L32e_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23413">
        <property type="entry name" value="PTHR23413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01655">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01393">
        <property type="entry name" value="Ribosomal_L32e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52042">
        <property type="entry name" value="SSF52042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00580">
        <property type="entry name" value="RIBOSOMAL_L32E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="123" mass="14345" checksum="3D36DBFB7407BF0B" modified="2018-02-28" version="1">MINKELLELRRAVKARKPEFVRQESWRYKRVKENWRKPKGIDSKMRLQVKGWPKIVKVGYRGPRVARYLHPSGYRDVLVHNVEELSRLDASRDAARIASTVGARKRAMIISKAKELGIKVLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCQ3</accession>
    <name>A0A2H5VCQ3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74440">
        <property type="protein sequence ID" value="GBC74440"/>
        <property type="gene ID" value="HRbin05_00480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="501" mass="55448" checksum="644049EE86836162" modified="2018-02-28" version="1">MLIPYSYILYRYTFINPLGSNNMRYTPLVLITILMLSSITSVIADGNSNAGNGSDDVYISYVEIIPSSLIVGDTFKIKAVVVNNSNATITYRGLCESPISAEFDDHVIVEYVPACLGFTINELKPGESVEVIGPSSGIVYKAGSAGLTKAVVTFTYYVGDSVEKVTKEFTFDINDGKNVVVDEQFKLSMNQGARITDGIDLAVRLVDVLEDSRCAEGVYCVRAGSVTILLEVESIYGIMYLELAKGDRGPDTVRIMNYTIRLLDVQPYPKVNEHIEKDAYTVTLIASKSIPMEHAAIKAYSHDGEKMIVVWNEHSKRGFMISNSKLLRLSVEQSKCIDMNYDKCFNAIVVMEDGSKAISVAIDYNDSMEMLVDGKIFIMKRMLVLFNDTHIEYSRIMIGKGEGDGYGSDGSVDATLVVTHIDGFNESVTAVNHYKYPVRGYRDAMLKLGDSVSNGCTITLKLIGFKVDAEGIEEPKAVFIREVIDRDRCLMHTSRQTSLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCQ8</accession>
    <name>A0A2H5VCQ8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00524</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000022">
        <property type="protein sequence ID" value="GBC74483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74483">
        <property type="protein sequence ID" value="GBC74483"/>
        <property type="gene ID" value="HRbin05_00524"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="243" mass="27189" checksum="58178A71BDE34440" modified="2018-02-28" version="1">MISTYQHSDDAVGANLAGKNILLSISSSDDVTIRRVKHLISKLSGYYARCTLLSQHDVALDGVDKRICNMMDEDEVRRTIRDVRPNITIHLTGNYDYNREVTSLSREEWDALVDRFINIPALISKETLNAIVYDGGREPSRFKNSNGMIIIVGPDAPYGKKVSNLLRARAEVFRGALRPFAVTATQELSEVLNSNIRVYLLLPGSIDGKEPDDGRLVDTCLYLASGRAINRVEVIYYPDEVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCR4</accession>
    <name>A0A2H5VCR4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">30S ribosomal protein S27e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps27e</name>
        <name evidence="4" type="ORF">HRbin05_00519</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eS27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74478">
        <property type="protein sequence ID" value="GBC74478"/>
        <property type="gene ID" value="HRbin05_00519"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00371">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000592">
        <property type="entry name" value="Ribosomal_S27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023407">
        <property type="entry name" value="Ribosomal_S27_Zn-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01667">
        <property type="entry name" value="Ribosomal_S27e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="zinc finger region" description="C4-type" evidence="3">
        <location>
            <begin position="29"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="74" mass="8279" checksum="6F2A8EDB40EC14DF" modified="2018-02-28" version="1">MSSIGGYSMVKKEHILIPKPRSAFILVRCSNCNTERVVYSHSSMSIRCRQCNSLLVRNTGGKAIIYGVEVNRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCS6</accession>
    <name>A0A2H5VCS6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HRbin05_00525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000022">
        <property type="protein sequence ID" value="GBC74484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74484">
        <property type="protein sequence ID" value="GBC74484"/>
        <property type="gene ID" value="HRbin05_00525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="67"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="315" mass="33529" checksum="8EB688E7D6D78EFB" modified="2018-02-28" version="1">MIGLDAIGILVVVVVGISAGILGSLLGLGGGFIIVPALAFLGIEPSRIAGTSMFTVLSTSASSTASYAMQRGSRSNYREREDHSNDSNRTNMGSSSSYDSNGDGDSSNDNDDGSDERDRQNKKKRRGSSRRGVGRIDYATASRLAVFALPGAVIGAYSSSLLDLASFKLYFALLLAGVASYILINPYYHVKEKHYPKQVSYAVSFLSGFIASLFGVGGGAILVPMMLMVLRMDMHVAVPTVHLIILLSSISGVATHAMLGHPEYMLAVMLVGGTFTGAQIGSRLLGRVRDIVLRRLVSIAMMIVAARLIYDSIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCT0</accession>
    <name>A0A2H5VCT0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00547</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74506">
        <property type="protein sequence ID" value="GBC74506"/>
        <property type="gene ID" value="HRbin05_00547"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="159" mass="16815" checksum="80E31DBCBF22C42E" modified="2018-02-28" version="1">MDDAGLNATLSSNGIPLLSPPSMPPALLLVVTTLPSFTVYGSLFSEPLTLDPWKPDPNSTPLTAGIENNALLRSDSNAPNIGSPNPMGMFNAIHSTTPPRESPSCLALIIASLISSAVLWSGHLTSLLYLNLFASIDRFESILIPPISRVYAITSMPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCT5</accession>
    <name>A0A2H5VCT5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Thioredoxin reductase</fullName>
            <ecNumber evidence="4">1.8.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trxB_2</name>
        <name evidence="4" type="ORF">HRbin05_00535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74494">
        <property type="protein sequence ID" value="GBC74494"/>
        <property type="gene ID" value="HRbin05_00535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="6"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="192" mass="21514" checksum="372BF5A65A263F86" modified="2018-02-28" version="1">MKSEERFAGKGVSYCATCDGPFFKGEDLVVVGGGDSAVEEALFLTKFANRVQIVHRRDKLRASKILQERAFTNPKISFVWNSVVEDILGDRKVNAVLIRDLTTDKRYELKCGGVFVAIGHEPNTQIFKGQIDMDEHGYIKVRDRTRSNIDGVFVAGDVHDPVYRQAITAAGFGCMAALDVERYLAEKYHHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCT9</accession>
    <name>A0A2H5VCT9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">K(+)-insensitive pyrophosphate-energized proton pump</fullName>
            <ecNumber evidence="10">7.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Membrane-bound proton-translocating pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Pyrophosphate-energized inorganic pyrophosphatase</fullName>
            <shortName evidence="10">H(+)-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">hppA</name>
        <name evidence="11" type="ORF">HRbin05_00555</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>diphosphate + H(+)(in) + H2O = 2 H(+)(out) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="7.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="10"/>
    <dbReference type="EMBL" id="BEHH01000024">
        <property type="protein sequence ID" value="GBC74513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74513">
        <property type="protein sequence ID" value="GBC74513"/>
        <property type="gene ID" value="HRbin05_00555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:pyrophosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="PTHR31998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0106">Calcium</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="224"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="503"/>
            <end position="524"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="583"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="661"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="site" description="Determinant of potassium independence" evidence="10">
        <location>
            <position position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="682" mass="70219" checksum="D078A2BE089FC51A" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCU0</accession>
    <name>A0A2H5VCU0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HRbin05_00554</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000024">
        <property type="protein sequence ID" value="GBC74512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74512">
        <property type="protein sequence ID" value="GBC74512"/>
        <property type="gene ID" value="HRbin05_00554"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070122">
        <property type="term" value="F:isopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140492">
        <property type="term" value="F:metal-dependent deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028090">
        <property type="entry name" value="JAB_dom_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14464">
        <property type="entry name" value="Prok-JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="6">
        <location>
            <begin position="5"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="140" mass="15575" checksum="DFABC380691651FC" modified="2018-02-28" version="1">MLDSVVIEFKQLEVLRGLAEKAYPYEACALLAGSVEVDGSSNTYRVRLVIEVDNADMSSMSFSIRDEDLINAYEIMSSSNLELVGIFHTHPFSNAYPSGKDIKYMQINPVPWIILAGDEIRAFIIDEGKGVKELRLLISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCU1</accession>
    <name>A0A2H5VCU1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">60 kDa chaperonin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">groL</name>
        <name evidence="6" type="ORF">HRbin05_00521</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TCP-1 chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74480">
        <property type="protein sequence ID" value="GBC74480"/>
        <property type="gene ID" value="HRbin05_00521"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03343">
        <property type="entry name" value="cpn60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017998">
        <property type="entry name" value="Chaperone_TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002194">
        <property type="entry name" value="Chaperonin_TCP-1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012714">
        <property type="entry name" value="Thermosome_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11353">
        <property type="entry name" value="PTHR11353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00304">
        <property type="entry name" value="TCOMPLEXTCP1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02339">
        <property type="entry name" value="thermosome_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00750">
        <property type="entry name" value="TCP1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00751">
        <property type="entry name" value="TCP1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="534"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="556" mass="60035" checksum="357C530A2B6C8965" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCU4</accession>
    <name>A0A2H5VCU4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphoribosylformylglycinamidine synthase subunit PurS</fullName>
            <ecNumber evidence="5">6.3.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">purS</name>
        <name evidence="5" type="ORF">HRbin05_00549</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000024">
        <property type="protein sequence ID" value="GBC74508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74508">
        <property type="protein sequence ID" value="GBC74508"/>
        <property type="gene ID" value="HRbin05_00549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003850">
        <property type="entry name" value="PurS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34696">
        <property type="entry name" value="PTHR34696"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02700">
        <property type="entry name" value="PurS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="SSF82697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00302">
        <property type="entry name" value="TIGR00302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="82" mass="9514" checksum="87636DDD079A2329" modified="2018-02-28" version="1">MPVYKVNVLIENKPYISDPEGDTILKDLVLKGGYQQVRSIRVAKMLKVEVEAKSVEDAREMVRRMCDELRLYNPMLSICRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCU6</accession>
    <name>A0A2H5VCU6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74526">
        <property type="protein sequence ID" value="GBC74526"/>
        <property type="gene ID" value="HRbin05_00568"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="124" mass="12727" checksum="D1659C0B036BDD28" modified="2018-02-28" version="1">MNKFALLAVVAGVIATWIGGSSVAMAQLYGSPGAGGDITATPEQLQECKQLGIPEFACTQHSILAKKRLTTAQQEGAYGSGTSMVAKTFGELGIYVAALGAIFGGISAAFFAMALRKPKIQKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCV5</accession>
    <name>A0A2H5VCV5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GTP-dependent dephospho-CoA kinase</fullName>
            <ecNumber evidence="3">2.7.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Dephospho-coenzyme A kinase</fullName>
            <shortName evidence="3">DPCK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00556</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the GTP-dependent phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3'-dephospho-CoA + GTP = CoA + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:61156"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; coenzyme A biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GTP-dependent DPCK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.-" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000024">
        <property type="protein sequence ID" value="GBC74514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74514">
        <property type="protein sequence ID" value="GBC74514"/>
        <property type="gene ID" value="HRbin05_00556"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00590">
        <property type="entry name" value="Dephospho_CoA_kinase_GTP_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007164">
        <property type="entry name" value="GTP-dep_dephospho-CoA_kin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40732">
        <property type="entry name" value="PTHR40732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04019">
        <property type="entry name" value="DUF359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006533">
        <property type="entry name" value="UCP006533"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="167" mass="18589" checksum="8A77CB2551715AB5" modified="2018-02-28" version="1">MQVSFSSDELSILKRPLGLLIEDSRVSRDILEHLLKDARLVISVGDATTERLIALGFVPDIQIVDGRERRGLRAEIKHMHKSEVRCRNPAGTVSKDAIDAIRKALTLDKPVRVYVDGEEDLLGLVVLKLAPDGSTILYGQPLEGIVLLRVDEEIKSRLKHLLSKLPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCW8</accession>
    <name>A0A2H5VCW8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AsnC_trans_reg domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00581</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74539">
        <property type="protein sequence ID" value="GBC74539"/>
        <property type="gene ID" value="HRbin05_00581"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="79" mass="8822" checksum="79A710228364102E" modified="2018-02-28" version="1">MGMRAYIEIDLEPGRDVIASASIIRQIDGVKEAHAVSEHCDILAIIEARDFKGIYNIVMRKIQIIKGVSDTRILPCIDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCY1</accession>
    <name>A0A2H5VCY1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00594</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74552">
        <property type="protein sequence ID" value="GBC74552"/>
        <property type="gene ID" value="HRbin05_00594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="97" mass="11282" checksum="81A604E4B4985CB0" modified="2018-02-28" version="1">MGDVLKGGQFFIVYDADGAFVLEDKTKRNLTVLEVSKDDRYGVDAEKGIIYDADGRGHRVSIRWYFPKDRFRLDDVLDVAKGIEEFYRRLREETCPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCY9</accession>
    <name>A0A2H5VCY9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphate import ATP-binding protein PstB</fullName>
            <ecNumber evidence="5">3.6.3.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pstB</name>
        <name evidence="5" type="ORF">HRbin05_00461</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.27" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74421">
        <property type="protein sequence ID" value="GBC74421"/>
        <property type="gene ID" value="HRbin05_00461"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="43"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="75"/>
            <end position="82"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="291" mass="32580" checksum="51618864CF59C267" modified="2018-02-28" version="1">MRLWSLLSKDYSYVEKVDMQGSKEVTVVRADDDGDGMNGKIVLEGREVGVLYDSKYAIKDVNIKIVRNTITAIIGPSGCGKSTLLRCFNRMNDLLDARIEGEILFNDHNIYSNGINVAEIRRLIGMVFQKPNPFPTSIYNNVAFGLKINGFKGDIDKQVEYALREAVLWDEVKDRLNDNAYSLSGGQQQRLCIARALAVEPEVLLMDEPTASLDPIASAKIEQLVTRLKEKITVVIVTHNIQQAARISDYVNVMMVDENMIGRLVEAGPTREVFENPKSKVTEDYISGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD08</accession>
    <name>A0A2H5VD08_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00621</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74579">
        <property type="protein sequence ID" value="GBC74579"/>
        <property type="gene ID" value="HRbin05_00621"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="79" mass="9147" checksum="66E81BE5E2A6FDD5" modified="2018-02-28" version="1">MSAPMINLDSKNILNKPVITSDGYLRGHIVGQTDKELVLMEGTWRVRRYNIPKTLVTNFDGSYIYLSIPDKELEKYRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD22</accession>
    <name>A0A2H5VD22_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Caffeyl-CoA reductase-Etf complex subunit CarD</fullName>
            <ecNumber evidence="2">1.3.1.108</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">carD</name>
        <name evidence="2" type="ORF">HRbin05_00636</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.108" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000032">
        <property type="protein sequence ID" value="GBC74592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74592">
        <property type="protein sequence ID" value="GBC74592"/>
        <property type="gene ID" value="HRbin05_00636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="1">
        <location>
            <begin position="31"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="295" mass="33044" checksum="F92EC1135D830880" modified="2018-02-28" version="1">MDHGNDNSINVVVMVKLEPDLSEGNVSYNPDGTLNRSQTKNILGPHSAIACRAAMYAKVCYDAWVAVCSMGPPTAEIALKDAMSICCADELHLYSDRIFAGADTLATAETIKHGIMRMGRRIDLVLSGHRAVDGETGQTGPQTAWKLGFNFIGNVIGYSIDVERRMVRARRKIYLPSLYTVLEDVECPLPALIALDPSYKDEYRKVSERLRYARFEKEARRRVMDYKSYLRIWSAKDLGVDVKYVGLAGSPTIVYKVEKIPKVKASRRARVVDPSNLDELREVGNLILNITWGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD24</accession>
    <name>A0A2H5VD24_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1,2-phenylacetyl-CoA epoxidase, subunit D</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">paaD</name>
        <name evidence="2" type="ORF">HRbin05_00641</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000032">
        <property type="protein sequence ID" value="GBC74597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74597">
        <property type="protein sequence ID" value="GBC74597"/>
        <property type="gene ID" value="HRbin05_00641"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008792">
        <property type="entry name" value="PQQD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041881">
        <property type="entry name" value="PqqD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05402">
        <property type="entry name" value="PqqD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="7"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="214" mass="24058" checksum="3695BC97A0E45B3A" modified="2018-02-28" version="1">MKAKVTEQQVLDALKQCMDPEIPLSVVDLGLIYGIDIDEENNIKIRMTMTTPGCPLRNTLVRDVKRALNKVEDIKDVSVEIVWDPPWTPERMSPEARAKVFGARSAQVHTAPPSPTGYGARSLRFTIDLERSKPLKHGQFVRQEDGSLVLVNDLGQGFMVNDALLEFWNMCDGSKSINEIIDEFSMKLRLPRIELEGQVVNLVQQMLEAGLLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD29</accession>
    <name>A0A2H5VD29_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="7">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">glnS</name>
        <name evidence="7" type="synonym">gltX</name>
        <name evidence="11" type="ORF">HRbin05_00632</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="7"/>
    <dbReference type="EMBL" id="BEHH01000031">
        <property type="protein sequence ID" value="GBC74588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74588">
        <property type="protein sequence ID" value="GBC74588"/>
        <property type="gene ID" value="HRbin05_00632"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02076">
        <property type="entry name" value="Glu_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004526">
        <property type="entry name" value="Glu-tRNA-synth_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00463">
        <property type="entry name" value="gltX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="9">
        <location>
            <begin position="105"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="10">
        <location>
            <begin position="411"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="111"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="586" mass="67138" checksum="114DF79ADD501B60" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD37</accession>
    <name>A0A2H5VD37_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulatory protein AsnC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">asnC_3</name>
        <name evidence="5" type="ORF">HRbin05_00512</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74471">
        <property type="protein sequence ID" value="GBC74471"/>
        <property type="gene ID" value="HRbin05_00512"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="158" mass="17954" checksum="7C7F3D8B83D7AD4F" modified="2018-02-28" version="1">MPKIDELDMKIMSELVKDASISVPRLSKKINVNASVVYSRIKRLIKLGLIKKYTIIVNEEMLGYNVRAVTGINMDSKMRDNIISGLMKIPEVREIAEVTGRFDILITLTAKTLDEIHHIVSDKIGRLDGVQRTETFIEMKRTIKEPTFSEVVLPLVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD47</accession>
    <name>A0A2H5VD47_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74481">
        <property type="protein sequence ID" value="GBC74481"/>
        <property type="gene ID" value="HRbin05_00522"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="61"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="346" mass="37322" checksum="4FE9C66EFEBFA2E0" modified="2018-02-28" version="1">MDLDLGIDLPSALRNIGYTVAMHDFFIDRIVRLGGISPDGLLSSMKGKIEAGGGSIRGIEQVEMKGGNAVNLAYALAMLDARCKLVTVADDYGRMMLRHTFTGLSNVDLILLNGKQGYTVSLEFVDGSRVANVMLSDLGDNAYFGADRLEGLEGVLSNAACIAVVNWTSNMKGTELVEKAFSTSSRALHFIDPADLGGRGKEFADVILEGRFRLDVLSMNENEARIVANTLELEPLPYNYSMDDVARLCRGIASTLAIRVDLHTPICSATSDGKDHEEVRAFKVDPRIATGAGDVWDAGDILGYLCKMDDHTRLLFANASAAYYVKNAIAPTLDDVLSLVSSVGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD52</accession>
    <name>A0A2H5VD52_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PINc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00668</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000035">
        <property type="protein sequence ID" value="GBC74624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74624">
        <property type="protein sequence ID" value="GBC74624"/>
        <property type="gene ID" value="HRbin05_00668"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="139" mass="15873" checksum="BE7C6B057CC7717C" modified="2018-02-28" version="1">MGMVMSSQAYIIDPTVLLLYFIGNEDAKTVVENIIEEHAYGYILEPMLVELFQKMVEYFGYTVASSRLEAIKNSNIRLINVDFELIRDAGRIKASNPSMPMVYAYMIALAKKFNATIVTADTRFRVSNINIKIEYINIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD53</accession>
    <name>A0A2H5VD53_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="2">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Alpha-IPM isomerase</fullName>
            <shortName evidence="2">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">DmdB</name>
        <name evidence="2" type="synonym">leuD</name>
        <name evidence="4" type="ORF">HRbin05_00670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LeuD family. LeuD type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000035">
        <property type="protein sequence ID" value="GBC74626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74626">
        <property type="protein sequence ID" value="GBC74626"/>
        <property type="gene ID" value="HRbin05_00670"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01032">
        <property type="entry name" value="LeuD_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011827">
        <property type="entry name" value="LeuD_type2/HacB/DmdB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02087">
        <property type="entry name" value="LEUD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="1 2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="3">
        <location>
            <begin position="35"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="162" mass="18189" checksum="B212208686C14D61" modified="2018-02-28" version="1">MMRGRVHKYARDNIDTDVIIPGPYLKIMDHNELAKHAMEGIDREFVKKVKKGDFILAGRNFGCGSSREHAPIALSYAGISAVLALSFARIFYRNAVDGAYLLPIEIGEDAYNEIEDGDELEIDIERNEVRNISKGKVYAMKPFPPLIKRIVDAGGLFNYTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD65</accession>
    <name>A0A2H5VD65_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000036">
        <property type="protein sequence ID" value="GBC74636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74636">
        <property type="protein sequence ID" value="GBC74636"/>
        <property type="gene ID" value="HRbin05_00680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002739">
        <property type="entry name" value="UPF0201"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01877">
        <property type="entry name" value="RNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="147" mass="16382" checksum="2B23A6201BCB0301" modified="2018-02-28" version="1">MDVKKIGSVFTSAEIELIVHATESLDKLIDALSSTLGVRSSILTREVLTGHHGNEIILLKGGVVGDDARNLADRLMGSLSSEDILRIYRDFDLYTDNRSSFYIRISKQEMVKGRIRLSQSDAVRIRLRLAKRMHKASLEALRSALVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD68</accession>
    <name>A0A2H5VD68_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-dehydroquinate dehydratase</fullName>
            <shortName evidence="1">3-dehydroquinase</shortName>
            <ecNumber evidence="1">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Type I DHQase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Type I dehydroquinase</fullName>
            <shortName evidence="1">DHQ1</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">aroD</name>
        <name evidence="2" type="ORF">HRbin05_00542</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I 3-dehydroquinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74501">
        <property type="protein sequence ID" value="GBC74501"/>
        <property type="gene ID" value="HRbin05_00542"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00502">
        <property type="entry name" value="DHQase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00214">
        <property type="entry name" value="AroD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001381">
        <property type="entry name" value="DHquinase_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01487">
        <property type="entry name" value="DHquinase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01093">
        <property type="entry name" value="aroD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0704">Schiff base</keyword>
    <feature type="region of interest" description="3-dehydroquinate binding" evidence="1">
        <location>
            <begin position="36"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="1">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>3-dehydroquinate</name>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>3-dehydroquinate</name>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>3-dehydroquinate</name>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>3-dehydroquinate</name>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="264" mass="30339" checksum="2A9E7079D6442404" modified="2018-02-28" version="1">MIISYKICTSIQARDSSRSLALDVARAFNEGSDMVEVRFDYSSKDAINDLLDVVMEHRDRMIFTCRSRDEGGAFNGSESERLMVLKRLASFRPMLLDVEYKTVERDEELYDHLRALNCDLLISYHDFNHTPSRNRLAEIMDGMLKYSRNVKIVAMAKSVEDNESILSLYDMIKDRYKKDDIQLVAFCMGEHGLASRVLCTMLGAPFTYAALDKPLAPSQLTLRQMRMIYKVMDENGYAKSIRNDRYTIDMVARLIGSVLHDMHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD69</accession>
    <name>A0A2H5VD69_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coenzyme F420:L-glutamate ligase</fullName>
            <ecNumber evidence="2">6.3.2.31</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fbiB</name>
        <name evidence="2" type="ORF">HRbin05_00672</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.31" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000035">
        <property type="protein sequence ID" value="GBC74628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74628">
        <property type="protein sequence ID" value="GBC74628"/>
        <property type="gene ID" value="HRbin05_00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052618">
        <property type="term" value="F:coenzyme F420-0:L-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002847">
        <property type="entry name" value="F420-0_gamma-glut_ligase-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01996">
        <property type="entry name" value="F420_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_ligase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="259" mass="28593" checksum="9A7B7825F9367AA1" modified="2018-02-28" version="1">MKVIGIRVKPRHERFDLFKVMVDSIRACNEHVEDDDIIVVSSKFAAMSQGRVIDMNSVVPAKDAYAISSMHNMDAKMAELVLREADHIFSGVPGFLLTVKDGMLAPNAGIDRSNVMHGLSILYPVDAFRVADMLRDKFLIHEGRRVGIVIADSRLMPTRIGTSGVALAVSGFEPVKDRRGSKDLFGNVMRVTLHAIADCIASAANLVMGETDESTPVAIVRGLSVRMDQRSYDWSDLAIEYEQCIYVRGLSMHGSKLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD84</accession>
    <name>A0A2H5VD84_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74654">
        <property type="protein sequence ID" value="GBC74654"/>
        <property type="gene ID" value="HRbin05_00699"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038664">
        <property type="entry name" value="Gar1/Naf1_Cbf5-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="134" mass="15103" checksum="C1649D82358E022A" modified="2018-02-28" version="1">MREKIEVGEVLHVARSGRMIIKSSISDVAVLSRGTILVDAKGRSVAKLIELIGPVQSPYISAMPLTDRVKKYVGATLYVERTGKKVRRQENDDGKSKSKSKRVERKSGRREMMGEKREEEKDEEEGEGRGKEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD87</accession>
    <name>A0A2H5VD87_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Segregation and condensation protein B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">scpB</name>
        <name evidence="4" type="ORF">HRbin05_00702</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74657">
        <property type="protein sequence ID" value="GBC74657"/>
        <property type="gene ID" value="HRbin05_00702"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="181" mass="20136" checksum="230B3C50397D02CD" modified="2018-02-28" version="1">MYASGRPLSIEEIQSAIGTDSRSKALKIARMLAEKVNSTFHALEVVESPSGSFVLQVKPSYYSIVRRFSSKPLLSKAALRTLAYIAYMQPVNVKRLAEVRGSQVYEHLRELRSLGFISYRVEGRSKMYHTTDKFAEYFGIASNGSYDGKELRAFLINKAMHVTSDPLQVDGAITTMAAQTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDA4</accession>
    <name>A0A2H5VDA4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00722</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000042">
        <property type="protein sequence ID" value="GBC74676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74676">
        <property type="protein sequence ID" value="GBC74676"/>
        <property type="gene ID" value="HRbin05_00722"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="35" mass="4325" checksum="3DFD18F8A481EE46" modified="2018-02-28" version="1">MAKRFNPERFARCTAKSYSRKEAKAKRVKIRRRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDA8</accession>
    <name>A0A2H5VDA8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00713</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000040">
        <property type="protein sequence ID" value="GBC74668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74668">
        <property type="protein sequence ID" value="GBC74668"/>
        <property type="gene ID" value="HRbin05_00713"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="213" mass="23854" checksum="132E6CAB55D4F354" modified="2018-02-28" version="1">MSSLLRKRNILFAISIILIASGLLILTIPSIPAASSIKDVKGDADALPLFPNKPVPMVRGYHDILNASVKRVDDGLLFSIELADSIEHYRDGYEVVYIWSIEYITASLQKREYKLVIPYFPEEQGLSVKGWYLAVFNASSNEWLIPMLKVEDMRGNRVDIDLDARVIGEPILFWWSVDVMVNVDTAVHGQPDYLMDSAPDGGKAMLSPLLTWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDB3</accession>
    <name>A0A2H5VDB3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH arsR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00732</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000044">
        <property type="protein sequence ID" value="GBC74686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74686">
        <property type="protein sequence ID" value="GBC74686"/>
        <property type="gene ID" value="HRbin05_00732"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="62"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="164" mass="18988" checksum="366DC6554A63700C" modified="2018-02-28" version="1">MKRQNINKNKLVMQQSNNNRYIVLNTIKNIQGIRYMELKRLTGLSYGTLTYHLTRLEREGSIRAVRSARKSRYYTSDVDDLQADIIECIRNRICKDIISMILEYGAVTLDGLAKALKKAKTTINYHIERLRARGIIEGKRIGRYIFYSLRDSSILDRLGALLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDB7</accession>
    <name>A0A2H5VDB7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00733</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000044">
        <property type="protein sequence ID" value="GBC74687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74687">
        <property type="protein sequence ID" value="GBC74687"/>
        <property type="gene ID" value="HRbin05_00733"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="170" mass="18179" checksum="86BB18E97E1F14EA" modified="2018-02-28" version="1">MRYTAYVIGIVVAAVLAVAATVQVSQQQQHTSGHTSGDGVGTIPMHPISHGGSTIVVHIASGDPKDARHMLSAEMGVRMALAMQQQGKDVIVFLDSYGTMLAPRNPTDDRLKALNSDLQQFAMQGGRVIVCSHCYQVLGNKAEDLTPGFEWAGPGKMSKVWSGNVIVIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBA6</accession>
    <name>A0A2H5VBA6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA(fMet)-specific endonuclease VapC</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">vapC</name>
        <name evidence="2" type="ORF">HRbin05_00002</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73974">
        <property type="protein sequence ID" value="GBC73974"/>
        <property type="gene ID" value="HRbin05_00002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041120">
        <property type="entry name" value="PIN_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18477">
        <property type="entry name" value="PIN_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="5"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC73974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="147" mass="16298" checksum="B7D0A97E2707BA90" modified="2018-02-28" version="1">MIRMVEVLVDTSFIIAMANIPIKGMDRLEVKLGRVEFLIPDVVVKELERIAIDAGVKRAREARAALQLIYDARFRSKARMIDITKVSDTEGKSAKEGKVGSKVDDLIVGYAESAGCYVATLDREMIRRLRGRCAGIITLQDDTLTIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBB1</accession>
    <name>A0A2H5VBB1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Putative L-ascorbate-6-phosphate lactonase UlaG</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ulaG</name>
        <name evidence="1" type="ORF">HRbin05_00003</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73975">
        <property type="protein sequence ID" value="GBC73975"/>
        <property type="gene ID" value="HRbin05_00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC73975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="226" mass="25014" checksum="1466740888851617" modified="2018-02-28" version="1">MLEYKGVRIAWLGHDTFKISSGGVVIYIDPYKLRKEARDKADLLLISHEHFDHLSIEDARKVIAADKTTVVTTKSCADSIRGVKVKEVKVVKPWDRVDVQGVSIEAVPAYNINKINPDTKKPFHPKDAGMVGFVITVDGVRIYHAGDSDAVEELRNLSNIDVALLPVSGTYVMTADEAVQAVGMVKPKIAIPMHYGTIVGSQKDAERFKSMVKECDVHILKPVDDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBB6</accession>
    <name>A0A2H5VBB6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt-precorrin-5A hydrolase</fullName>
            <ecNumber evidence="6">3.7.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cbiG</name>
        <name evidence="6" type="ORF">HRbin05_00010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.12" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73982">
        <property type="protein sequence ID" value="GBC73982"/>
        <property type="gene ID" value="HRbin05_00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043779">
        <property type="term" value="F:cobalt-precorrin-5A acetaldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021745">
        <property type="entry name" value="CbiG_mid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021744">
        <property type="entry name" value="CbiG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002750">
        <property type="entry name" value="CobE/GbiG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036518">
        <property type="entry name" value="CobE/GbiG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038029">
        <property type="entry name" value="GbiG_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01890">
        <property type="entry name" value="CbiG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11761">
        <property type="entry name" value="CbiG_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11760">
        <property type="entry name" value="CbiG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159664">
        <property type="entry name" value="SSF159664"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159672">
        <property type="entry name" value="SSF159672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="CbiG_N" evidence="4">
        <location>
            <begin position="87"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="CbiG_mid" evidence="5">
        <location>
            <begin position="171"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="CbiG_C" evidence="3">
        <location>
            <begin position="269"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC73982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="408" mass="45130" checksum="F0768CEB0014662C" modified="2018-02-28" version="1">MDVHATTNTNHNHNHNNNHNHHDHPTNAKKGRVAVVAITKHGLEIAGRLKSIMREWDVYAPEKFRAAPVATSMMEVNWYNEPSAVLISKLFNSYNALICIFSLGAVIRMIAPYIRDKRSDPAVLVIDDAARFVISALSGHLGGANALARLVARILNSTPVITTAADVNETIAVDLLGSEFGWRIDEASEHNITMLSAAMVNEEPIGIYQDAGERGWWSKELPKNVRIFNSIDELNASGLKALIITDRLIDDSRYAELLGRAVVYRPKSLVVGLGLHWDTSSDEIARGIENTFKDAMLSMYSIRCIATLERGYEVKGLKEFSERTGIPVEYYTKEQLASIKVPNPSTLVKMYEGTPSVAEAAALASASGKGGKDMEKDREKCELVVEKRKFPPNLTVAVARIIYDSQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBD4</accession>
    <name>A0A2H5VBD4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putative amino acid permease YhdG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">yhdG</name>
        <name evidence="6" type="ORF">HRbin05_00021</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73993">
        <property type="protein sequence ID" value="GBC73993"/>
        <property type="gene ID" value="HRbin05_00021"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="426"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC73993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="735" mass="81028" checksum="D90515365BEEFAF9" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBE9</accession>
    <name>A0A2H5VBE9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73990">
        <property type="protein sequence ID" value="GBC73990"/>
        <property type="gene ID" value="HRbin05_00018"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="549"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC73990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="597" mass="65791" checksum="C17DA7EB78210186" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBF6</accession>
    <name>A0A2H5VBF6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00039</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74009">
        <property type="protein sequence ID" value="GBC74009"/>
        <property type="gene ID" value="HRbin05_00039"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="284" mass="33119" checksum="B32679DCBF905E59" modified="2018-02-28" version="1">MHDDIIQETSRLLGILAKHDSLTLFLESVEGIDASTDTPARLGMSKKQYYTRLKQLIGAGLITKSKGKYVQTTMGRMLYERCLKLVFEQVRNAKKLIMADILKDSGRFDMDEIYRLLQIKVENGNARLITDYDMLIDVLQERMKDVKNQAWYATRYFNEYIVSKAIELHRRGVDVRILVDRALVEKYISEYMGMSKHGTSKYELERFKMFTDPFYPDKLERKIVDVPFSFIILDGRYVGIELVNVNNPNKFYAGIYIENEYIASQMKSLFETLYTSANIVSKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBG2</accession>
    <name>A0A2H5VBG2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RNA_pol_L_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HRbin05_00050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74019">
        <property type="protein sequence ID" value="GBC74019"/>
        <property type="gene ID" value="HRbin05_00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009025">
        <property type="entry name" value="RBP11-like_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13656">
        <property type="entry name" value="RNA_pol_L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="RNA_pol_L_2" evidence="4">
        <location>
            <begin position="16"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="114" mass="12521" checksum="9468C01477B0473E" modified="2018-02-28" version="1">MFMMEVSLIERDEKGVTIKVKGEDISVLNILQYEIAKYKSVDIVGVAQRHYLIPEYEFRVSMKHAGDDPFKVVAEAVGSALNVVRSMKEEASSIVSSSSSNSSDSSRSNSNGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBG7</accession>
    <name>A0A2H5VBG7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">7-carboxy-7-deazaguanine synthase</fullName>
            <ecNumber evidence="6">4.3.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">queE_2</name>
        <name evidence="6" type="ORF">HRbin05_00065</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74034">
        <property type="protein sequence ID" value="GBC74034"/>
        <property type="gene ID" value="HRbin05_00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040085">
        <property type="entry name" value="MJ0674-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01099">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="155"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="421" mass="49215" checksum="BFEDB66A3D2279C1" modified="2018-02-28" version="1">MGRDFGSLWIWKEGNVRDRLGWYYSVATNSMPAKYLICKRVPVDPSIYNMDIDSLWKEYDTALERFIRLWSDVRSRSITIRDLPIAKVNLLDLLLAIVKGSLHACNFCRWQCKVDRTTGGKLGACKLEAESRVSTFFHHMGEEIVFRGIKGSGTIFFTSCNMRCAFCQNGDISTDRFNGSVVTPYMIALMAYKLRLEGCHNINWVGGEPTIHLHNIVEAIHEMSRFIINKVRYEDELFVIKSINADMPYRYSMSSSNAYYGDEFNVPQLWNSNFFMSREALNVLRCIMDVWLPDLKFGSNKCSLRLARTPWYWETVTSNIKQVHCWDEDMVIRHLIMPGHVKCCTKQVLEWVADNMPEVLINIMDQYRPENYCDPYSPNYDPAYKDMARFPSKQEIDEAYRYAKELGLNFEMITFEKHFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBH6</accession>
    <name>A0A2H5VBH6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fluoroacetyl-CoA thioesterase</fullName>
            <ecNumber evidence="1">3.1.2.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">flK</name>
        <name evidence="1" type="ORF">HRbin05_00083</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.29" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74052">
        <property type="protein sequence ID" value="GBC74052"/>
        <property type="gene ID" value="HRbin05_00083"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025540">
        <property type="entry name" value="FlK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36934">
        <property type="entry name" value="PTHR36934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF014972">
        <property type="entry name" value="FlK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="127" mass="14371" checksum="52370966AD8D82E5" modified="2018-02-28" version="1">MLHAGIEMERVVKVDSSMVIDFLGDDGRVLSTPSMVDAIERLCREMVKPYLKEDEDTVGVRIDAKHMAPTPLGMSIRVHALLVSVDGRRLVFHADVHDEHEKVGEAVHERFVINKSRFVARVRAKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBI1</accession>
    <name>A0A2H5VBI1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00077</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74046">
        <property type="protein sequence ID" value="GBC74046"/>
        <property type="gene ID" value="HRbin05_00077"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="285" mass="32780" checksum="7CA75BA810610B8A" modified="2018-02-28" version="1">MGSKMMKWYELRLYPNFKDGEEEMLNLLYRVDEFAIFIIRKNGMTRILVRTDDINAMHFSGIQNARLERLEWNPSLRYSLTRYYKMRVHSALPIVEKVRPSIIYTMLEELDNIGNSDGKGGVECILACYAKYKDEAYSISRWIMRKEGHEHSLVKALKSLFTSNERVRRLSPLTESLVEKARWKMRLKHFHTVLALGAEDVRTLDMLEGALPYGLVAYSNNKRAGDHFSDLSSVVEHARVLKKCILSDVELASIVALPKDASILRLATTDRRTFTTGLVVDADTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBJ4</accession>
    <name>A0A2H5VBJ4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00088</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74057">
        <property type="protein sequence ID" value="GBC74057"/>
        <property type="gene ID" value="HRbin05_00088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="162" mass="18159" checksum="AAAA95127D622F29" modified="2018-02-28" version="1">MVKPRKAPGEDKKKLTKWQIIMPVILIGVGTGIAFIISQFISGKPPLQQCITSEDLPFKLHAVLSVTIDGKPVEVPEGIGRDENCIRPLHTRGDGNVYVIYSRPIRFTLLDLLRLWNLDTEGYEISIWVKGKGQQEFINIGSDPAKVAIEDGLNIRLELRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBL8</accession>
    <name>A0A2H5VBL8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="11">5.4.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">glmM_1</name>
        <name evidence="11" type="ORF">HRbin05_00117</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="11"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74085">
        <property type="protein sequence ID" value="GBC74085"/>
        <property type="gene ID" value="HRbin05_00117"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03087">
        <property type="entry name" value="PGM_like1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024086">
        <property type="entry name" value="GlmM_arc-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03990">
        <property type="entry name" value="Arch_GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="3"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="151"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="254"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="376"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="454" mass="49495" checksum="A79E412A530E5B10" modified="2018-02-28" version="1">MAKLFGTNGVRGVFGKDLTLDLALRLSYALATYYRQGPLLLAYDGRHSSPLIASVVKAGLNAMGIDVHDAGLVPTPCLQYCTKRLGYRGGIMITASHNPPEYNGIKVMASDGVEVPREDELKIEDIYFEERFMQSKGIGRDERLGDAVDLYLQGIRSLVDVDRIRSKGMKVVVDLGNGAQAVAVPRLLNSLGCKVVTLNGMIDGSFPGRGSEPTIDNLGELASSVKANGADLGIAYDGDGDRSIFCDEQGNIYTGDRSGALLVEHVLAKEGEGQRGKVKVVTPVNSSMLIDMVAARYNAKVIKTKVGSVEVSREMVRASALVGLEENGGFMYAKHIPVRDGAMSTALMLEALALRDEPLSSLIGRYKRFYQYKTKFPCTREQSSSIIDALKGTSSRVETIDGIKVWVDDESWIMVRQSGTEPIMRLYAESSSEQRLKQMVDAYVEKIRSLLGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBQ5</accession>
    <name>A0A2H5VBQ5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="4">IGPS</shortName>
            <ecNumber evidence="4">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">trpC</name>
        <name evidence="6" type="ORF">HRbin05_00152</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TrpC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74119">
        <property type="protein sequence ID" value="GBC74119"/>
        <property type="gene ID" value="HRbin05_00152"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_A">
        <property type="entry name" value="IGPS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="5">
        <location>
            <begin position="45"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="284" mass="31571" checksum="111187EDD9F8B9F6" modified="2018-02-28" version="1">MKGKRMDGGEGGIEEKEEEEHGYLERLVDAARSAVRSGHYEFGFTIHHRIISMRDAILSCKRSGKNAIIAEVKFASPSMGRIRDYTSPQTLARDMVDAGAMALSVLTQPNYFNGSIEYLMNVRVAVDVPLLMKDIIVSREQVDAAYRAGADCILLISSIYTEGLADDTLERMIDRAHAYGLEVILEVHDEDEFDQALKSTADIIGINNRDLKSMNVDVSNTARILAKHDNNKATTNKPIISESGISSVEHIRYLKQYKVDAFLIGTSIMASDNIKNKVRELVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBQ9</accession>
    <name>A0A2H5VBQ9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster repair protein YtfE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ytfE</name>
        <name evidence="2" type="ORF">HRbin05_00157</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74124">
        <property type="protein sequence ID" value="GBC74124"/>
        <property type="gene ID" value="HRbin05_00157"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="15"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="194" mass="22391" checksum="4E8A172B7B014954" modified="2018-02-28" version="1">MNIKISGIGWYMSATYELRRDHEVIMQVLNAMDTLRMLLRQGKDVPLEVIYDTIDFAKNFTDRCHHGKEEDVLFPALNAAGMPKDEGPIAVMLREHRQGREILAKIEDALTRHKQGSSSLDGVIAGIEEYIMLMQHHIFKENNILFNIADMLLSSKSNELNKGYERVEHEVMHDKHGHYKEMVESIVERIDAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBT3</accession>
    <name>A0A2H5VBT3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium-dependent dicarboxylate transporter SdcS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sdcS</name>
        <name evidence="6" type="ORF">HRbin05_00181</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74148">
        <property type="protein sequence ID" value="GBC74148"/>
        <property type="gene ID" value="HRbin05_00181"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="383"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="464"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="490" mass="52496" checksum="D405C4112CBE30E7" modified="2018-02-28" version="1">MNGVSIKMNLLGLVLGPLVFLAVFLMGGMIVIDVGARTVLALVAWMVVWWITNAIPLYATALLPLVVLPASNVMQIGSIAVNYADRTIFLLLGSLMLARAIEMAGLHRRFAIRMLLILGNDSKSMLGGFILVTALLSAFMSNTVVAAMMIPLALSIISVMEEGHRRRIAPALMIVIAYSASIGGVITLVGTPPNLIFASIASNMGYDVTFLSWLPIGLPVGSILLLLLWLYLLYVHRLRDVKIIESRDVVINEANRLGRISRREKAVLAVFIATIAAWMSRSVWGSYLPSIDDAVIAVSAALLLFAIRVKDSDESKEDGASVKDKGRAGVGEVRLLTWDEASRIPWGVLVLIGGSLALANAFTATGLDKIVASSLAIEASPSLMVLFITAVTVFITELMSNTAVATLMLPVVSSVAEHVGMEPLQLMLAATLAATLSFMLPVATPPNAMAFASGYLTVAYMIRMGFIMNLLSIAVITAIIYIITPYYSVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBT7</accession>
    <name>A0A2H5VBT7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00196</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74162">
        <property type="protein sequence ID" value="GBC74162"/>
        <property type="gene ID" value="HRbin05_00196"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="91" mass="9270" checksum="50E169C1676BC52E" modified="2018-02-28" version="1">MKVTLSAALSPSVIEATENTTGLPPLLSVIVIPIASLVVSARVAVTLFNVTGLSIPPTVTVNPSASLPWNEKVIVLVVPVPPTVIAPAVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBU6</accession>
    <name>A0A2H5VBU6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional hemolysin/adenylate cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cya</name>
        <name evidence="2" type="ORF">HRbin05_00191</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74157">
        <property type="protein sequence ID" value="GBC74157"/>
        <property type="gene ID" value="HRbin05_00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="699"/>
            <end position="717"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="736" mass="76276" checksum="04F4B5E21E8273A0" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBW7</accession>
    <name>A0A2H5VBW7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome partition protein Smc</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">smc</name>
        <name evidence="2" type="ORF">HRbin05_00220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74186">
        <property type="protein sequence ID" value="GBC74186"/>
        <property type="gene ID" value="HRbin05_00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="241" mass="27323" checksum="9DA77BCECB4CA1D4" modified="2018-02-28" version="1">MYDEEFKKGMLRMLKEDEEFRYAVAGLIGLEDIRASVARLQDSVAKLEDSVARLQDSVAKLEDSVARLQDSVAKLEDSVARLQDSVAKLEDSVARLQDSVARLIDTQTKTELAIASLRKDVGRLANNFGFTLEEIAATKLPRLLMDEGITIRRGDIRLRYHIRVDNKEREVDVYVKGKGRDGKDITIIGEVKGRIDRSDVRRFDEAFKNIDAFKFIFGHTIRPEAEGEAAERGIRLYATYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBX1</accession>
    <name>A0A2H5VBX1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SpoVT-AbrB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00223</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74189">
        <property type="protein sequence ID" value="GBC74189"/>
        <property type="gene ID" value="HRbin05_00223"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="8"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="319" mass="36349" checksum="A75CB12F4CEE564A" modified="2018-02-28" version="1">MRYTRKVQRIGSSLLISLPKEWVENNGIERGSIVLIETANDNSLRIYPTLDEVKESKEVVINYPSPYYEPIANKITGAYLLGYDLIKVKANTPISYEERERIKEAIEKLVSLEIVDEDATHIVAQFLLDATTLDAEKILYRISSIVSGMYRDVITALQSKDKGILKSIARRDDEVDRQYFLLVRLLRSLLKDQRLAAKMNLTSIEVLDYRLAAHLLESAGDSAVELARAVESLEHEVDEHSNLVEVAKMVERIQDTSVKAFINHDRKGSIDVMKQYLMLSEHISSMKQDTDAKVLGFMHLLDKFARIWVDIADLVMPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBY4</accession>
    <name>A0A2H5VBY4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00237</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74203">
        <property type="protein sequence ID" value="GBC74203"/>
        <property type="gene ID" value="HRbin05_00237"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="205" mass="24079" checksum="39280874606958D6" modified="2018-02-28" version="1">MLGERSVKDAVNKAIDSMLMIEREDNRIHVDEVARCLRRSYYDRRERSIPAKERLILMKRSMRINSSQSKEHHLEDLVLIASADTIVDDAVIRFEVVDRLPSTPEPASLIALNASLWIFNKEEGALVYLTRDGDSIQFSLTRDKRLFDETIRRAKVLSMLLKENRVPVFEPSEQCMNCPYYEKCYIQHKRYENPTLERIFGLKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBZ1</accession>
    <name>A0A2H5VBZ1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00244</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74209">
        <property type="protein sequence ID" value="GBC74209"/>
        <property type="gene ID" value="HRbin05_00244"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="243" mass="27346" checksum="910270A5B09F2AE9" modified="2018-02-28" version="1">MKVVEYDSIKMESPYIFIGLPDVGLVGSIAVSYMIDSIKMAEIGHVESDLLPPLLLVRHEEVKNPIRLYSNGSNMIALISEMPIHPSILQEFVTSIAEWFKRVNPRLVVSITGIPVQNRLNIDKPKVFYIATDEHTSSLMRSTHALVFEEGILFGAYAAILKACMSRNIPTLTLFTQSHLNFPDPFASIEALEVLNKALNIGIDLNELREEAEMIRIKTRELMKQTESMLAEPRLKATPTFYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBZ6</accession>
    <name>A0A2H5VBZ6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="1 2">2.7.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">APS kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ATP adenosine-5'-phosphosulfate 3'-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Adenosine-5'-phosphosulfate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cysC_2</name>
        <name evidence="1" type="synonym">cysC</name>
        <name evidence="3" type="ORF">HRbin05_00134</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1 2">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 2">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the APS kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="1 2"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74101">
        <property type="protein sequence ID" value="GBC74101"/>
        <property type="gene ID" value="HRbin05_00134"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Phosphoserine intermediate" evidence="1">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="180" mass="20503" checksum="063357B57701ED89" modified="2018-02-28" version="1">MKGFTVWLTGLSGSGKTTIGRTLQHRLINLGYRAELLDGDEVRRNLSPDLGFSKQDRELHARRVVYISKLLTRNGIIAIVSLISPYRAFRAYAREELKDFVEVYVKCSINTCIKRDPKGLYRKALNGEIQDMTGIQDPYEEPLNPEVTVDTDKQNIEECVDAIMNRLHQLGYITTLAVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC15</accession>
    <name>A0A2H5VC15_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosome biogenesis GTPase A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rbgA</name>
        <name evidence="2" type="ORF">HRbin05_00271</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74236">
        <property type="protein sequence ID" value="GBC74236"/>
        <property type="gene ID" value="HRbin05_00271"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023179">
        <property type="entry name" value="GTP-bd_ortho_bundle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="1">
        <location>
            <begin position="136"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="293" mass="33385" checksum="2C9E0C25358261EB" modified="2018-02-28" version="1">MRIARWEQIRRMIDSSDGVDIVVEVIDAREPEYTRSRMLEEYVLKNGKALIIALNKSDLVPEYVARGWASRLSSEGLRCVCTSSKSLDGIDTLKRLMLKYARRGSAEYHKGMVYTRTMIQIPRRIAKERGRISIAMVVGYPKTGKSSIVNALRRRYGASTSPVPGSPGYTRGMQIFKIASYLYMYDTPGMLPIDLEHVDPVAYAVRCSAPEELRDPVEPALRLIERILANNPDAIRDAYGLSITDLYKVLEHIARKRGWFYKSDKEPLVEEAARAVIRDYHEARLNFYIPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC21</accession>
    <name>A0A2H5VC21_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleoside-triphosphatase HRbin05_00273</fullName>
            <shortName evidence="3">NTPase</shortName>
            <ecNumber evidence="3">3.6.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Nucleoside triphosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00273</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="EC" id="3.6.1.15"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the THEP1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.15" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74238">
        <property type="protein sequence ID" value="GBC74238"/>
        <property type="gene ID" value="HRbin05_00273"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00796">
        <property type="entry name" value="NTPase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004948">
        <property type="entry name" value="Nuc-triphosphatase_THEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43146">
        <property type="entry name" value="PTHR43146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03266">
        <property type="entry name" value="NTPase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="194" mass="21131" checksum="ADF54C3C8E9369FB" modified="2018-02-28" version="1">MLILLTGEPGVGKSTVLMRLIDMLKEKGISVGGVVAREVRDAGKRRVGFEFVNVIDGSSARLASLSSSAGVGGGIEGPRIGKYSVDLDGCRIAAMMLLRAINSSSKVVVFDEIGPMELLSSDIVDALRALLDAISSNSSSKYTAIVVIHKRFKHWIISRYREMASIVIEVNRDNRDALPLMLLNTINDKWDKVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC22</accession>
    <name>A0A2H5VC22_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nop domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00277</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NOP5/NOP56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74242">
        <property type="protein sequence ID" value="GBC74242"/>
        <property type="gene ID" value="HRbin05_00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031428">
        <property type="term" value="C:box C/D RNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032040">
        <property type="term" value="C:small-subunit processome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030515">
        <property type="term" value="F:snoRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.246.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029012">
        <property type="entry name" value="Helix_hairpin_bin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045056">
        <property type="entry name" value="Nop56/Nop58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042239">
        <property type="entry name" value="Nop_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002687">
        <property type="entry name" value="Nop_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036070">
        <property type="entry name" value="Nop_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012976">
        <property type="entry name" value="NOSIC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10894">
        <property type="entry name" value="PTHR10894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01798">
        <property type="entry name" value="Nop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00931">
        <property type="entry name" value="NOSIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89124">
        <property type="entry name" value="SSF89124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51358">
        <property type="entry name" value="NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nop" evidence="3">
        <location>
            <begin position="285"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="398"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="398"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="442" mass="48857" checksum="12BAAD90D421F60C" modified="2018-02-28" version="1">MIALYNATFLIGIVAEDDDGMSRCNLLLLENGIVAIDDADGSTKVVDVLKFNRESMAREYSMIKSGLDDSRLSTILSSLKAKGYTSLACNDPILVDAAIRHGFSAVEMSAEDRLKVQHNKVAIIVEAGLAEDEQDALLALHEFSVSLSSIKVAEASAKPDQHIIQCINTIDELDKIVNIMGARLREWYGLHFPELDGIVQSLPSYCDIVLRFGRRDAITVDTLRSIGLQDEKKVDAIARAALTSKGGMISDENLILLQRIAEEIKHLSKQRDALARHMEDEMARVAPNLKDILGATIGARMIAKAGGLERLALLPASTIQVLGAEKALFRALRTGTRPPKHGIIFQHPSVHSAPRWQRGKIARAIATKVAVAARIDAFTGTKDDTLLAKLNERLEEIREKYVEPRHEEKEEGEKKRKGRGKGRGGGGGEERRERRRRRGRKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC30</accession>
    <name>A0A2H5VC30_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74220">
        <property type="protein sequence ID" value="GBC74220"/>
        <property type="gene ID" value="HRbin05_00255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="135" mass="15589" checksum="7BC7C08C05D0E6ED" modified="2018-02-28" version="1">MTNYIMRIANNEEFETSIFSRRAYYTAMRRRWEKGMKILLAKKIEGKGDAFIGYAVVDKALSIDELSMEERDMCRRNGWNTKTVFSRLVRLQPPIPIKYTPVGRWPQKGALLHGAPIGDDDLNSVIELASMKINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC32</accession>
    <name>A0A2H5VC32_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00279</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="4">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74244">
        <property type="protein sequence ID" value="GBC74244"/>
        <property type="gene ID" value="HRbin05_00279"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037117">
        <property type="entry name" value="Dihydroorotate_DH_ele_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019480">
        <property type="entry name" value="Dihydroorotate_DH_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10418">
        <property type="entry name" value="DHODB_Fe-S_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="2" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="3 4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="284" mass="31356" checksum="538D6D539F514B1A" modified="2018-02-28" version="1">MLTDTDGDMDKDRMRLVRVEEVRYESPTVRTLIFKDDLASEARAGQFLMVWIPRVDEIPMSVMLDPYDRAGYAALTVRRHGYSSTALYNMHEGSTIGLRGPYGRAFTASNGNVILVGGGTGLVPLLRLCKMLSNSTGIRVTFIMGSRSKDEVIFEDLARRLVGNNGKVIVCTDDGSYGFKGYASDMLKALLEDASSKGERFDMVYTCGPEAMMLKVLKIVDEYGLEAQASLERIMKCGIGLCSSCCIGRYVLCKDGPVMDARDILARNEFGAYARDKSGRLVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC39</accession>
    <name>A0A2H5VC39_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Coenzyme F420-dependent oxidoreductase</fullName>
            <ecNumber evidence="2">1.-.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00174</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.-.-.-" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74141">
        <property type="protein sequence ID" value="GBC74141"/>
        <property type="gene ID" value="HRbin05_00174"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="319" mass="35845" checksum="0636F1B8C303F57D" modified="2018-02-28" version="1">MLLDDRQVIEYARRAESMNLHSIWVPESWGRDAFVTLSYIASLTRSVMLGTAIVNIYARSAASTAMAINTLDLYSNGRAVLGLGAGSKRLAEDWHGLEFKNNIARMKEYVDVIRLISRGERVDYNGRVVRVKGMRLGFKPLRSNIPIYIAATNQGMLKLAGEVGDGAILFLMPMNELDKQVRMLKGINPRLDVALVLITAVSNDTQRAIERAKKSIAFYTAVGSIYARFLAEHGFKDEVEHIREEYRRNGLKDIHMLVSDRMLSSLALAGSIDDCIKQLRSFIKGIDLPILLINPVYNAEEDYIVFEHMMEEVVRDGGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC40</accession>
    <name>A0A2H5VC40_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Purine nucleoside phosphoramidase</fullName>
            <ecNumber evidence="3">3.9.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.9.1.-" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74230">
        <property type="protein sequence ID" value="GBC74230"/>
        <property type="gene ID" value="HRbin05_00265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="PTHR46648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="16"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="108"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="161" mass="18229" checksum="E0C5543470A42F7B" modified="2018-02-28" version="1">MDDASRSSVKEGDECIFCLIVEGKRDAAVVYEDDAMMVFMDKYPISNGHILVIPKRHHTTILDMESRDVGMLFALVHRVAKAVVSALNAQGFSIAQNNGKVAHQVVPHVHVHIVPRFIDEERGRWPSRRTATMDELRSIAERIRQHLLNNTNTMDVELITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC49</accession>
    <name>A0A2H5VC49_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylmethionine-8-amino-7-oxononanoate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">7,8-diamino-pelargonic acid aminotransferase</fullName>
            <shortName evidence="4">DAPA AT</shortName>
            <shortName evidence="4">DAPA aminotransferase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">7,8-diaminononanoate synthase</fullName>
            <shortName evidence="4">DANS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diaminopelargonic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bioK</name>
        <name evidence="4" type="synonym">bioA</name>
        <name evidence="6" type="ORF">HRbin05_00184</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine = (7R,8S)-7,8-diammoniononanoate + S-adenosyl-4-methylsulfanyl-2-oxobutanoate</text>
            <dbReference type="Rhea" id="RHEA:16861"/>
            <dbReference type="ChEBI" id="CHEBI:16490"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="EC" id="2.6.1.62"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; biotin biosynthesis; 7,8-diaminononanoate from 8-amino-7-oxononanoate (SAM route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.62" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74151">
        <property type="protein sequence ID" value="GBC74151"/>
        <property type="gene ID" value="HRbin05_00184"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00834">
        <property type="entry name" value="BioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005815">
        <property type="entry name" value="BioA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00508">
        <property type="entry name" value="bioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="120"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="325"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM" evidence="4">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="468" mass="52658" checksum="918A05A1D61BEED4" modified="2018-02-28" version="1">MHKHYTYKNGNLKTKDKAYVWHPYTQMSDWFRIDAPVIVRGEDFYLIDDKGNRYLDGVASMWCNVWGHSRKEIVDAIVEQAKVLQHSTLFGLCNEPSIVLAELLVKMTKGMDKVFYSDDGSTAMEVAIKMAIQYWYNKLGSNKRREIIALENGYHGDTIGAMSIGYIEHFFKPYKPLLFKVRHVPSPYLYRKSREMSDADYVQYCIDMLEHELKRGEGRVAAVVMESGAQIAGGVIVYPDGYQREVSRLCKRYDTLLVLDEVATGLGRLGSMVEYIAQDSMPDIVAFGKMLTAGYLPLAATLASDEIFNAFLGKYDEGKHLFHGHTFTGNPIACACAVANLRLYEQERLISKVKSSSALLAERLEEFRGYPIVGDVRHKGMLAAIELVKGNSNSNSKSNSKSKDPLLTLSDGRRINYAIMEEALKRGLFIRPLGHIMLIVPPLAIGREELNMLIDKALEVVGTISKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC51</accession>
    <name>A0A2H5VC51_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00307</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74272">
        <property type="protein sequence ID" value="GBC74272"/>
        <property type="gene ID" value="HRbin05_00307"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038723">
        <property type="entry name" value="ArnR1-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14947">
        <property type="entry name" value="HTH_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_45" evidence="1">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="88" mass="10445" checksum="6D09EB9941C4A40B" modified="2018-02-28" version="1">MHKKDRRERFDIIYNILTILNNENVYKTILARKAKLDSRSIEKYVNLLQRTNLITVDASKGGRHILKITEKGRAFLNIYEELIRLIKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC58</accession>
    <name>A0A2H5VC58_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00316</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74279">
        <property type="protein sequence ID" value="GBC74279"/>
        <property type="gene ID" value="HRbin05_00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="32" mass="3374" checksum="CF4C70571F572794" modified="2018-02-28" version="1">MNRTQTRRVGSHGSSNSGSSKSSSSTKDMIAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC64</accession>
    <name>A0A2H5VC64_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74278">
        <property type="protein sequence ID" value="GBC74278"/>
        <property type="gene ID" value="HRbin05_00315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="186" mass="20142" checksum="94303A0CAFA31107" modified="2018-02-28" version="1">MNLPIIGVAPVSSQNLSTAILALSLVEHATTFGKDLLIIDAAASIRSRVLFISSMYTPSFALAMNCSMYFVFTLVPILIPAESISLSIFSIMLMHYALAVYNFKLGLFNLFMIKAKQQQQQSIYQSIIQTKSTSLLCLSNYCRVVIPSTISSSSSLISSFIFATLSPPTTPALIILEPVATATCAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC79</accession>
    <name>A0A2H5VC79_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HRbin05_00215</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74181">
        <property type="protein sequence ID" value="GBC74181"/>
        <property type="gene ID" value="HRbin05_00215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="171"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="83"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="516" mass="59704" checksum="500BEE665A04691D" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC83</accession>
    <name>A0A2H5VC83_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamine synthetase</fullName>
            <ecNumber evidence="2">6.3.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Glutamate--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glnA</name>
        <name evidence="7" type="ORF">HRbin05_00344</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74306">
        <property type="protein sequence ID" value="GBC74306"/>
        <property type="gene ID" value="HRbin05_00344"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="6">
        <location>
            <begin position="54"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-AMP-tyrosine" evidence="4">
        <location>
            <position position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00030668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604809-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="422" mass="48079" checksum="0DACB396321A2888" modified="2018-02-28" version="1">MDGSSIKGFAQIYESDMILKPDPNTFAIIPWKDQGRTARMICDVYWGYTGERLSRDPRAVAQRAEGMLKDEGFNVSYWGPEVEFFVFNRVGWEAMVPSRGISYTIESVEAPWSNDSSHTLRLKEGYMPAEPYDTLTYLRNQCMQVLNDYFGIPCEAHHHEVATAGQCEIDMRYDTLTNAADNTMTYKYVVKNIAKMNNLIATMMPKPLAMDNGSGMHVNVSLWNDNKNEFYDANDEYAELSQIGRYFAGGILEHAESLCAIVAPTTNSYRRLVPGYEAPVYIAWSKGNRSAIIRVPVYFRGKKQAASKRIEFRAADPSCNPYLCFSAILAAGLDGIRKKRDAGEPVDENIYLMSAEKRRELGIRQIPPTLIDAINALKSDDLYLKSVFTQDLIDKIIELESKDYMEIKLRPHPYEFYLYFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC86</accession>
    <name>A0A2H5VC86_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplN</name>
        <name evidence="3" type="synonym">rpl14</name>
        <name evidence="5" type="ORF">HRbin05_00332</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74294">
        <property type="protein sequence ID" value="GBC74294"/>
        <property type="gene ID" value="HRbin05_00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="144" mass="15604" checksum="93CB90E821621364" modified="2018-02-28" version="1">MAGKSRAVSAKGVEEFKPHITRAIPVYANLVCADNTGAKIVQVIQVNKYKGRLSRYPAASVGDLVTVVVKKGPPELRKQIFGAVIVRQKYPIRRPNGLRICFEDNAAILITPEGDVKGTDIKGPVAAEAAERWPRIANLASMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC89</accession>
    <name>A0A2H5VC89_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">4-phosphopantoate--beta-alanine ligase</fullName>
            <ecNumber evidence="1">6.3.2.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Phosphopantothenate synthetase</fullName>
            <shortName evidence="1">PPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-4-phosphopantoate + ATP + beta-alanine = (R)-4'-phosphopantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:27930"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:61294"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the archaeal phosphopantothenate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.36" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74191">
        <property type="protein sequence ID" value="GBC74191"/>
        <property type="gene ID" value="HRbin05_00225"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02224">
        <property type="entry name" value="PPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002855">
        <property type="entry name" value="PPS/PS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038138">
        <property type="entry name" value="PPS/PS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40695">
        <property type="entry name" value="PTHR40695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02006">
        <property type="entry name" value="PPS_PS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004853">
        <property type="entry name" value="UCP004853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="181"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="187"/>
            <end position="188"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="199"/>
            <end position="200"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="264" mass="29562" checksum="736522863144F621" modified="2018-02-28" version="1">MRIPENHPRAESLRIRERLVECLRRGIVVEQGLIAHGRGEAFDYLLGERTTIYAREAIRASVAMMLLADHPVISVNGNVACLCAGDVVRLASLTNARIEVNLFYRSYEREKAIEMLLKEHGASTVYGVGDRASMSIPELMSERRRVDRDGIYSADVVLVPLEDGDRTEALVRMGKKVVAVDLNPLSRTAKSATITIVDNITRAMPLMVETAKWLKDEPRDRLNEILRSFSNARNLEASLAVIRGSVDDMYVEREREGREGGIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC92</accession>
    <name>A0A2H5VC92_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00354</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74316">
        <property type="protein sequence ID" value="GBC74316"/>
        <property type="gene ID" value="HRbin05_00354"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="168" mass="18519" checksum="A6592A6E1CF81443" modified="2018-02-28" version="1">MNKADAKNLLLEEMEEAFYRKDVEYFKALLKHEDFDIRARAVCILVEIAEGEDAVEPICDVLLNDPNALVRHEAAFSLGQMGYAKAVDALISAMLKDDSPFVRHEAAIALGVIGSESARRALIQALNDESKEVRESAEIALVNLDYLAYSRQKGSSSVNSRFARLTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCA5</accession>
    <name>A0A2H5VCA5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DHHA1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00356</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74318">
        <property type="protein sequence ID" value="GBC74318"/>
        <property type="gene ID" value="HRbin05_00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHHA1" evidence="1">
        <location>
            <begin position="226"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="325" mass="36064" checksum="612908329A2BF992" modified="2018-02-28" version="1">MVNVCLSHKEDPDGIVSASLIKYAYPNTIVILADYSDLLERLEEAVRIEGLDHLFICDMGLSKANEERFFKVVEEASKRSRVTYIDHHHLEEESKDRLRGYGVELVHSIAECTSILIYHNLLKENIPSRFALLAGLAAVIDEMDGREIASRILKSYDRHFVEFEATLLAYAIYQNQHREEFLLTLVDGLVKDMPHAIDGVLESAKEYAQKITNNISVIENGARKDDGIVYIQAVDLPASTVANMLLTMHKSIKVAIAYKQRGDKMVVSLRGSNLCKLHLGKLANDVASELGGSGGGHEKASGAMLPKDSINIFIERVKGLINGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCA8</accession>
    <name>A0A2H5VCA8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chaperone protein DnaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dnaJ</name>
        <name evidence="8" type="ORF">HRbin05_00246</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74211">
        <property type="protein sequence ID" value="GBC74211"/>
        <property type="gene ID" value="HRbin05_00246"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="6">
        <location>
            <begin position="8"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="7">
        <location>
            <begin position="150"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="5">
        <location>
            <begin position="150"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="386" mass="43628" checksum="9DA146D7C2D429ED" modified="2018-02-28" version="1">MSKNSKPDYYEVLGVSKNASKEEIKQAYRRLALKYHPDRNKSPDAEEKFKLISEAYAVLSDDEKRKLYDMYGHAGLEGRYTSEEIFKGAKFDIDEILKDLGFDLDFDRIFERFFGFSMGSPFFWQESKGRGGREPLVIDVEIGLEDVLHGKRMEVEVPTIVQCSTCKGTGAMPDSRIRTCTVCKGTGQVKRVIEQSRFGTFVSIEPCRECNGKGRIVERPCITCNGTGRVRRIERVGVSIPAGLEDGTMLRLDDGHGSKGNRYGMDSDAVDGYDVYIRVRVKPHPLFKRSNSDIVYEAKVSFPRLVLGGDVKVPLLDGGYYTLKIPPGTQPDTVFTIKGKGLPRHDGYYYGRGDQLVKVSVKVPTPSTLSERQRRLIEELDREFRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCB8</accession>
    <name>A0A2H5VCB8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chemotaxis response regulator protein-glutamate methylesterase</fullName>
            <ecNumber evidence="5">3.1.1.61</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">cheB</name>
        <name evidence="5" type="ORF">HRbin05_00377</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl-[protein] + methanol</text>
            <dbReference type="Rhea" id="RHEA:23236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="3.1.1.61"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74339">
        <property type="protein sequence ID" value="GBC74339"/>
        <property type="gene ID" value="HRbin05_00377"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16432">
        <property type="entry name" value="CheB_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008248">
        <property type="entry name" value="CheB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000876">
        <property type="entry name" value="RR_chemtxs_CheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="17"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="CheB-type methylesterase" evidence="4">
        <location>
            <begin position="160"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="347" mass="38015" checksum="250B51CB9F676E2B" modified="2018-02-28" version="1">MSTTDNNNSSSNNKMINIAIINDSPYFLSILEDIAKSNNFNVIGKFTNARNALSFIYNSNYVDVILLDLEMPDMDGISFIEQVLSKRFVPIIVTTNYDESWIAKISNIGAIDFVSMNNKPINELNNMIAQKIRIAYMMNSMIRSSCRKASSNSNNNRYAHYDGKIVIIGASTGAPRIVADILTSIPPDINSCIIVVQHMPKGFTDTYVSMLSSRANIKVKRAEDRDRIVNGIVLVAPADYHLIVDNNHVRLEQGPKYAHVRPSANVTMVTAANMYGPNVIGVLLSGMGFDGAFGMKVIKMNGGFTIAQDESTSVVFGMARTACMVNAVDLILPAGSIADAIIRAVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCC1</accession>
    <name>A0A2H5VCC1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00382</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74343">
        <property type="protein sequence ID" value="GBC74343"/>
        <property type="gene ID" value="HRbin05_00382"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="99" mass="10814" checksum="3A04EDAA9F4038C1" modified="2018-02-28" version="1">MKVSRFFISGFIGGIAYKLGAGSKDMAEDGERSAIYKIRWEILVMAISLILIVVVVYAIPNDFSLKMLEQREKQRALEQASRGQQSNGTSSSIGGSSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCC4</accession>
    <name>A0A2H5VCC4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Na(+)/H(+)-K(+) antiporter GerN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">gerN_1</name>
        <name evidence="6" type="ORF">HRbin05_00386</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74346">
        <property type="protein sequence ID" value="GBC74346"/>
        <property type="gene ID" value="HRbin05_00386"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="291"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="319"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="3"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="362" mass="39685" checksum="4DEBB5166C59D0BA" modified="2018-02-28" version="1">MGFGLALLANYLGLSMAIGAFLMGMMIASSPRASVITEKVVPLRDLFGTVFFISIGMLISLNAILDNLIISLPIVVIAILSKFIGNFIATSIVGYGRDSASTVGIMMMPRGELSFVMAKQGIDLNATRESMMPITMLVSLASIFVVPLFSRALPTIVDPRSIIPIRLLNMLEAPARVTRGILQNVQQKDSALKVGRIFSRLLINMAIIVAMITIVLLSDGLISLLYNTFSSLKILPYNIFKIVFMIGAVAYPLLNILGRAGEITDAIFEEVQRRIVRYPVITRKMDHLHRVIRNTVLSIVVLIVTSFVIPSLAFGNMDIVLPASIAAVVIFVYLLLDTFIVVNRRIEKSLIDILVKDDGNDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCD1</accession>
    <name>A0A2H5VCD1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HVO_2753_ZBP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00393</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74353">
        <property type="protein sequence ID" value="GBC74353"/>
        <property type="gene ID" value="HRbin05_00393"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044720">
        <property type="entry name" value="HVO_2753-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011668">
        <property type="entry name" value="HVO_2753-like_ZBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40733">
        <property type="entry name" value="PTHR40733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07754">
        <property type="entry name" value="HVO_2753_ZBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HVO_2753_ZBP" evidence="1">
        <location>
            <begin position="11"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="60" mass="7069" checksum="64AB591476E75B2C" modified="2018-02-28" version="1">MSQRAIALPTCVSCNRVIMPNDRCVKFNCPRCNKFLIWRCESCREFARMYRCKECGFEGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCD3</accession>
    <name>A0A2H5VCD3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Demethylmenaquinone methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.163</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">menG_2</name>
        <name evidence="5" type="ORF">HRbin05_00396</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74356">
        <property type="protein sequence ID" value="GBC74356"/>
        <property type="gene ID" value="HRbin05_00396"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="239" mass="27021" checksum="B839599E0BE0BDC5" modified="2018-02-28" version="1">MVSIRMGLRDEWGSIISVLREIIPVYDKVNNVISLGRAEEMRRLGIVEGVEDGYLVLDAGSGFGNMSKSMLSIFPNVKVVMLDPIAEMLYLANERMDDGKYRGRISLVSGIFEYIPFKSNTFDAIVCGYSFRDAVIMKDAIREFHRVLKDDGRLIIVDIGKPDDPFVRLGVTLYIRFILAILAFFAAGRLGLKFAAIYDTYKRLPKNSEMVTMLRERFGSVRFVSRMFGAAIIFIASKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCF1</accession>
    <name>A0A2H5VCF1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00408</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74368">
        <property type="protein sequence ID" value="GBC74368"/>
        <property type="gene ID" value="HRbin05_00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="147" mass="16912" checksum="1D590E07DCA33F9E" modified="2018-02-28" version="1">MARVLYWHLTPQEVLAKPYPVGKLLHWEIRCIISKESYSSIYWFKAGVPYDKEPILGLAFYAIGISKELEDEMIEFIHGKVGGRLIRRGERTFFADARIGIDNEYVAGFALSMEDKFNARCEIWLEFDLLSDDEVKSLYTAKAVPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCG1</accession>
    <name>A0A2H5VCG1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00422</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74382">
        <property type="protein sequence ID" value="GBC74382"/>
        <property type="gene ID" value="HRbin05_00422"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002849">
        <property type="entry name" value="DUF131"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01998">
        <property type="entry name" value="DUF131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="78" mass="8606" checksum="044629DC7A64D155" modified="2018-02-28" version="1">MVMDARLLMFIGFALVLIGMIIVAFAMLRRAGSLQGRSMGFILLGPIPIVWQGSRSLLLIVPIALLIAIIFFIMVSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCH2</accession>
    <name>A0A2H5VCH2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00428</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74388">
        <property type="protein sequence ID" value="GBC74388"/>
        <property type="gene ID" value="HRbin05_00428"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="288" mass="32189" checksum="296D2134F52837CE" modified="2018-02-28" version="1">MTNGSIVRGSWSRRFMMAAIIQAVILLLIVSTAIAPYNSYAQDISMHDEDLTLIVNIEASRGHLMQALNNKSIGNDNGAIAHAGHPAAEHLDKIAPIIEKRNPELINELRDKLTRLPSKVPAISYEELRAEINAIDALFENASNLISDENKGSVQFWFEVMKMLLEHTEEEYEEGVEEEGKVSSAVEYEDAQAFIVRAEHVFTTKVKDSISSDTSVVIERFFNDVKMAMDEKRSADRIKELVDGIMPVIPEFPINLMLILVGVVALTIMIGRVLMPIKATIYNGYSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCI5</accession>
    <name>A0A2H5VCI5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HRbin05_00446</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the diphthine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74406">
        <property type="protein sequence ID" value="GBC74406"/>
        <property type="gene ID" value="HRbin05_00446"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00559"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004164">
        <property type="term" value="F:diphthine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11647">
        <property type="entry name" value="DHP5_DphB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036809">
        <property type="entry name" value="AF1782-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004551">
        <property type="entry name" value="Dphthn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023140">
        <property type="entry name" value="DUF357"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10882">
        <property type="entry name" value="PTHR10882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04010">
        <property type="entry name" value="DUF357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158372">
        <property type="entry name" value="SSF158372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00522">
        <property type="entry name" value="dph5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="6">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="DUF357" evidence="7">
        <location>
            <begin position="307"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="372" mass="41365" checksum="35D7A4812966A70C" modified="2018-02-28" version="1">MLILVGMGIHGYKGLSIEAMEAIKGADKVYVEAYTSPVKSRDIDALRALRDDVVEVHRWFVEDGRRILDEARAGDVVLLAYGDPLIATTHIELLVRARSSGIACKVIHSSSIVTAALGECGLHVYKLGRVATVVSSPIANTSTYYAIYSNLMQMNHTLLLLEYDQEHGYFLAVGSALRLLLDCEARERMNAIDEDTFAIVASRVGMEDMGIVGGRIGSLLKYSEEHGFGEPPHTLIVTGSLHFTEVEALRASVMLLDEPIDNSKRVSARAEMMLPNYIARAYNALSRAREYIMHAKGSAGDKAKDKDKDDTIERIKDMIDNAEYYLSDAERFAREHRYENAILALGYAEGLIDALRYLRDIDPWESKKSTIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCI8</accession>
    <name>A0A2H5VCI8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00452</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74412">
        <property type="protein sequence ID" value="GBC74412"/>
        <property type="gene ID" value="HRbin05_00452"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="3"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="208" mass="22579" checksum="F71737A588D4AD55" modified="2018-02-28" version="1">MGIRILAFSDIHGDRALVARLKDTVSISRASIDVAVCCGDITPVHGSTIEAARMIGDLGVRTLVVPGNFEMPNDLRIACKELNWTDLHGKYIEVKGYVFAGCGGGNISPFSTPYELGEDQFNELLSKLKGINRNGRLVLLTHCPPYGVVDEPKQGMHVGSNAIASYVIQEKPLAQFCGHIHEQGGKEGMLEGSRIINVARNIRIVELP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCJ1</accession>
    <name>A0A2H5VCJ1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00434</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74394">
        <property type="protein sequence ID" value="GBC74394"/>
        <property type="gene ID" value="HRbin05_00434"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="113" mass="13472" checksum="75870B8EDAD3D5EE" modified="2018-02-28" version="1">MERAERIACRKAVKLHVFMPSNRRIWTVVGNRHEYWIRPPDYCTCKDYYFRARAVAIEGRGEGKASCYHLKAVEIAEVREMVDEVHFNDDEYDGFIRALIDMMYKQVTKDNDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCK3</accession>
    <name>A0A2H5VCK3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nitrogen regulatory protein P-II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">glnB</name>
        <name evidence="1" type="ORF">HRbin05_00466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74426">
        <property type="protein sequence ID" value="GBC74426"/>
        <property type="gene ID" value="HRbin05_00466"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="118" mass="12930" checksum="18803DC9D397C8B4" modified="2018-02-28" version="1">MKTINSSMKKIEAIIASEKVDIVYRALKRYGVDNIFIVNGYGKGLFQIVLTGARGTGSYKPELMPASKIELIVADREVEDVLDIIAKNAGIGVNEGLVGRAVITPIEQIRRLEKTVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCK4</accession>
    <name>A0A2H5VCK4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">50S ribosomal protein L23</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplW</name>
        <name evidence="4" type="ORF">HRbin05_00339</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74301">
        <property type="protein sequence ID" value="GBC74301"/>
        <property type="gene ID" value="HRbin05_00339"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="87" mass="9818" checksum="AABA33A12D2D0478" modified="2018-02-28" version="1">MNAEQARSIIIRPYITEKIYTKMDKEDILAFIVHDKADKQSIKEAIKILYNVDAVDVNTARTIYGKKAYVKFKAGAARDLATKLGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCK6</accession>
    <name>A0A2H5VCK6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hypoxic response protein 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hrp1</name>
        <name evidence="4" type="ORF">HRbin05_00469</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74429">
        <property type="protein sequence ID" value="GBC74429"/>
        <property type="gene ID" value="HRbin05_00469"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013087">
        <property type="entry name" value="Znf_C2H2_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00028">
        <property type="entry name" value="ZINC_FINGER_C2H2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50157">
        <property type="entry name" value="ZINC_FINGER_C2H2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="32"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="3">
        <location>
            <begin position="97"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="C2H2-type" evidence="2">
        <location>
            <begin position="182"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="220" mass="23993" checksum="FB08299B04D1688C" modified="2018-02-28" version="1">MSYPSEEEEREGGGYEYEDIESLLNKPVEYVLTTNVVTLEGSMSAADAASIMKERNSRSVLVTHNGEAIGIVTKTDILFKVMAQGKNPNKVRLREIMSSPIITISPKTSISDALAVMEKHVLRQVIVSSGSTVIGMVTREGLFERIHKASMVTSQTALKGTPVCIINPKAIAYVKEAVEAKLSCPYCGSPFDDKNALSKHIDRLHIGSGVLEGDVRRIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCM0</accession>
    <name>A0A2H5VCM0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00464</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74424">
        <property type="protein sequence ID" value="GBC74424"/>
        <property type="gene ID" value="HRbin05_00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="69" mass="7695" checksum="32550C78AF3FB49B" modified="2018-02-28" version="1">MKRYIVGALALSLLSLILSDAYALGAPQPLSKPPGLIVTYLATLLSVLFFMLIQHLIRKSFYSKYRLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCM6</accession>
    <name>A0A2H5VCM6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl12</name>
        <name evidence="6" type="ORF">HRbin05_00494</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein P1/P2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74453">
        <property type="protein sequence ID" value="GBC74453"/>
        <property type="gene ID" value="HRbin05_00494"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006414">
        <property type="term" value="P:translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05832">
        <property type="entry name" value="Ribosomal_L12p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01478">
        <property type="entry name" value="Ribosomal_L12_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038716">
        <property type="entry name" value="P1/P2_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027534">
        <property type="entry name" value="Ribosomal_L12/P1/P2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022295">
        <property type="entry name" value="Ribosomal_L12_arc"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03685">
        <property type="entry name" value="ribo_P1_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="63"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="105" mass="11135" checksum="335B8C6636B3F951" modified="2018-02-28" version="1">MAMEYVYAALLLHKTGQKIDEDSIKNVVKAAGVEPDDVKVKALVSALAEINIDEALKSTPLVAAPSAAPAEAKPAEAKPKEEKKEEEEEKKGEEEAMAGLSALFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCN0</accession>
    <name>A0A2H5VCN0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkanesulfonate monooxygenase</fullName>
            <ecNumber evidence="2">1.14.14.5</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ssuD</name>
        <name evidence="2" type="ORF">HRbin05_00474</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.14.5" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74434">
        <property type="protein sequence ID" value="GBC74434"/>
        <property type="gene ID" value="HRbin05_00474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008726">
        <property type="term" value="F:alkanesulfonate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019952">
        <property type="entry name" value="F420_OxRdatse_Rv1855c_pred"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03560">
        <property type="entry name" value="F420_Rv1855c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="332" mass="37793" checksum="835138D1FE31E480" modified="2018-02-28" version="1">MDSMGMSNHHDSRLEFGVLLPQGWIDDLKGLGFEYIKRFALTAEALGFSLWAYDHFIPYKEYRPFIGKPMLECWTLLSSIAGVTSKARIGQVVTCNSYRNPALLAKMASTLDYISNGRLEFGIGAGWYEEEYVSYGYQFPSARARIEQLDEALNIIRAMWVDEEASTFHGKYHKVINAVNYPKPVQKPHPPIMVGGSGRLLLKVAAKHADIYNCPFVDVDELTDKLRVLKEHCMNIRRDYSTIIKSLLMRVIIADRHETLIDKIRVVKRSDESIDWFISRNKGSTIIGTPDDVARELQGYAAIGVRHFILHPLPIEEDLESLRLLIDACKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCN1</accession>
    <name>A0A2H5VCN1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplA</name>
        <name evidence="5" type="synonym">rpl1</name>
        <name evidence="6" type="ORF">HRbin05_00497</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Binds directly to 23S rRNA. Probably involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Probably involved in E site tRNA release (By similarity). Binds directly to 23S rRNA.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Protein L1 is also a translational repressor protein, it controls the translation of its operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74456">
        <property type="protein sequence ID" value="GBC74456"/>
        <property type="gene ID" value="HRbin05_00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_A">
        <property type="entry name" value="Ribosomal_L1_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023669">
        <property type="entry name" value="Ribosomal_L1_arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0678">Repressor</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="218" mass="23999" checksum="F4D962091841356F" modified="2018-02-28" version="1">MDSDLLNLVREAREKAGKRNFKQSVDLILVLKDIDVKKGFSINEVVALPHTPNKKAKVCVIASGDLALRARRANADKVIEGTELSALANNKREAKKLSSMYDFFLADTQLMPTVGKVLGPVLGPKGKMAMPLPFNAPVDAMLDRLRSSTRARTRNQLMVACRIGDEDMDDKMLAENAMAVINAVEKKLPAGERNIAEIMLKFTMGRVARLIPTKVVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCN6</accession>
    <name>A0A2H5VCN6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L10</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Acidic ribosomal protein P0 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpl10</name>
        <name evidence="2" type="synonym">rplP0</name>
        <name evidence="4" type="ORF">HRbin05_00496</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74455">
        <property type="protein sequence ID" value="GBC74455"/>
        <property type="gene ID" value="HRbin05_00496"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.105.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00280">
        <property type="entry name" value="Ribosomal_L10_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022909">
        <property type="entry name" value="50S_L10_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043164">
        <property type="entry name" value="RL10_insert_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040637">
        <property type="entry name" value="RL10P_insert"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17777">
        <property type="entry name" value="RL10P_insert"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RL10P_insert" evidence="3">
        <location>
            <begin position="114"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="288" mass="31913" checksum="B5A82651422EC00A" modified="2018-02-28" version="1">MIQQQQQAKVYPEKKVRMYRMLQEEASRYRAIALVKMDKVRSTQLMPLRKILADEAKMIMVKNRLAVKALSGSGVKGIEKILKEMEGQNLLIFTNMNPFKLQMLLEKNKVYLPAKGGDVATEDIVVPAGNTGLAPGPILSEFREAKIQTKIEEGTVWIAKDTVVAKAGEVISMKLASLLSKLGIKPIKAGVNLHMVLEDGLVYRSEDLKLDIEAYRKSIEEAYSNALTLAVNAAYPTKESIAMIVSRAYSNALTLAVNAAYPAREVIRELLMLAEAHAQTIARQANIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCP0</accession>
    <name>A0A2H5VCP0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74444">
        <property type="protein sequence ID" value="GBC74444"/>
        <property type="gene ID" value="HRbin05_00484"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006276">
        <property type="entry name" value="UspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="10"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="151" mass="16550" checksum="91A469B7D48EB721" modified="2018-02-28" version="1">MEEKRDKRSKRIVVAIDTSDSAIHVIEKAAEVAEMVGADVVVLTVVEVPLVASEGEMNMARIASEEKRIAEYHKQLIDRYFAGSTDMLVESMILYGDAGDKICELAEKIHADLVVVGSRGLGRIESMLLGSVSEKVLRKCRCSVLVVKSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCR2</accession>
    <name>A0A2H5VCR2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Molybdenum cofactor guanylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.77</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mobA</name>
        <name evidence="2" type="ORF">HRbin05_00518</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.77" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74477">
        <property type="protein sequence ID" value="GBC74477"/>
        <property type="gene ID" value="HRbin05_00518"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061603">
        <property type="term" value="F:molybdenum cofactor guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="3"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="236" mass="25734" checksum="FA7EB74AA709A7FC" modified="2018-02-28" version="1">MIAVVMAGGRGSRLAMGEKPLVKINGKPMISYVIDALLYSRCFSAITVAVSNNTIRTKRYIMDEYVNGSDHGIGLSKSKGYSNCKVMLVDTPADGYVVDLNSLILASRGHDYEYEDGYYNLFIIPADLPLLDEHIVRHIVEIAGSGRYSSAWLAVMTSKEFLTSLGLSCNGCIESNGSVLCYTGINIINTRGVERVPAIVDEEYIILDDARVAVNVNTLEDLKVAESLSKYCIGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCR7</accession>
    <name>A0A2H5VCR7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Probable cobyric acid synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">cobQ</name>
        <name evidence="9" type="ORF">HRbin05_00515</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 6">Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CobB/CobQ family. CobQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74474">
        <property type="protein sequence ID" value="GBC74474"/>
        <property type="gene ID" value="HRbin05_00515"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015420">
        <property type="term" value="F:ABC-type vitamin B12 transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00028">
        <property type="entry name" value="CobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004459">
        <property type="entry name" value="CobQ_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21343:SF1">
        <property type="entry name" value="PTHR21343:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00313">
        <property type="entry name" value="cobQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="8">
        <location>
            <begin position="4"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="289" mass="31849" checksum="7897F6BE46DE3F70" modified="2018-02-28" version="1">MRCIMIQGTASSAGKSIMVTALCRILADQGYRVMPFKAQNMSSNVYVTKDGLEMANAQALQAFAARVEPDVYMNPILLKPLGEYRSSVVILGREYKVMHARDYYRFAISKGLSIVLSSLQHLASYSDVVLIEGAGSPAEINIARYDIANMRLAEAINAPVLIVADIDRGGCFASMIGTLTLLKRRERDLVRGFIINKFRGDASILAGALSRFERISGKRILGVVPFIDDLALPEEDSLSSRRGHGSTSTLTHNEPQHDHLDAMVDRLSKVVKSSIAMDEVMRILDIRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCS0</accession>
    <name>A0A2H5VCS0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Poly(3-hydroxyalkanoate) polymerase subunit PhaC</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">phaC</name>
        <name evidence="2" type="ORF">HRbin05_00401</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74361">
        <property type="protein sequence ID" value="GBC74361"/>
        <property type="gene ID" value="HRbin05_00401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="195"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="473" mass="54424" checksum="ABF71F70E0BD1A23" modified="2018-02-28" version="1">MTMIEYVRSRSMPLPLVYNRLALEWMGAVSSMLKIYDTYSSIFYKALMMLLQEDGVSSKENPYMRMLNIMDAMLDEELKSERFAHLLTDYLDSWLSIHAMLKRIYPVRHYDIMLEDILAEQFRSYTRMLSFMLSTQNLPIDASGYDVVYIKGKVRLLHYRGGKGYPILIVYAMINRYHIMDVSKDKSVVRRLIEGGLDVYMLDWGHMGYEDEHLSLEDYIHILDEVVDKVREVSSKDRISMLGYCWGGIVSLIYASLYKQKLNSLIVMAAPVDFDKDDGILAVWAKAIDARRLVEEYGHMNGQALDIAFLLRNPVRYTVMKYLNLWKRINDRAFVETFYAVERWLYNTPTVPGRFYEQIIEDLYKGNMLVRGLLEVDGKRVDLKSIDIPLLTIVAENDDLTAPASTLAVNDHVSSKEKRVMSIPGGHVGLCISSIAHKQLWPNVARWVIEKARESSIEEANGRSVGGGKENQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCT4</accession>
    <name>A0A2H5VCT4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00511</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74470">
        <property type="protein sequence ID" value="GBC74470"/>
        <property type="gene ID" value="HRbin05_00511"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="33" mass="3370" checksum="EDAD7A43053DAC5E" modified="2018-02-28" version="1">MLNATMSSVVAAMILVDVLVLVTTGSMGTFALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCT8</accession>
    <name>A0A2H5VCT8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative_PNPOx domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00551</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000024">
        <property type="protein sequence ID" value="GBC74509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74509">
        <property type="protein sequence ID" value="GBC74509"/>
        <property type="gene ID" value="HRbin05_00551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019920">
        <property type="entry name" value="F420-binding_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03618">
        <property type="entry name" value="Rv1155_F420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="5"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="130" mass="14835" checksum="7598E0415F7A7702" modified="2018-02-28" version="1">MSVEKVEVLLKDKNLAFFATISKDGSPHVVPVWVDFKDGYIIVNTTTSRAKYKNVKRDPRVTISIVDRNDPYNAAMIKGRVVEEVKGEEAEEHIDAMAKKYLGLDRFPFRVDGEERVMLKIMPEKVVLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCU5</accession>
    <name>A0A2H5VCU5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">aroA</name>
        <name evidence="10" type="ORF">HRbin05_00545</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74504">
        <property type="protein sequence ID" value="GBC74504"/>
        <property type="gene ID" value="HRbin05_00545"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="9">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="EPSP_synthase" evidence="9">
        <location>
            <begin position="107"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="73"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate" evidence="7">
        <location>
            <begin position="126"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="202"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="346"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="464" mass="50105" checksum="3F123042AC008C40" modified="2018-02-28" version="1">MRDSVEVRRSRIDGSIVCPPSKSYTHRAIVISSLVDDGKASIVRNALLARDTNATIHGCRVLGSYIGLEDDGYGGGSSRITSRSTRDSIGNASGGSEGSRGSRGRMLIVYGRREFTLGYREIDAENSGTTIRILAAVSALVKEGSTLLYGDSSLNRRPMQPLLDALKQLGVQCRSLADGTPPLLINGHGIEGGEARITGSISSQFISALLIPSVYARHDVVLSIMGEQVSRPYIDSTIAVMRAFSARVDNDDYKHYSIARQEYKHTNFTVPGDFSSAAIMLAAGALAGGSVRVEGLDFTLPQGDSRIVDILRDMGARIHVDTGRGMVHVEESMLDGGAFNLADTPDLLPVVAILALKSKGRVEIRGVTHARFKETDRIANLARELSKFGAVVKELDDGLIITPPKVLKNAMLESYDDHRLFMVLCIASMLTEHSIVRGLSSVDVSYPSFLDDLVRIGADVRIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCW0</accession>
    <name>A0A2H5VCW0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00441</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74401">
        <property type="protein sequence ID" value="GBC74401"/>
        <property type="gene ID" value="HRbin05_00441"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="195" mass="20590" checksum="1FB6827694E9034E" modified="2018-02-28" version="1">MLSLSEFFADILLIRLLLSLSSCSSLVTSMLLTLLTSSIAFSNLSLSSPKAFIRSLRVEIFAFSVERSDMSVLICSCITSISSPSLSILSLLSLIICSPLASVPLTCSISASIFAISVIIALLFPSISCIIASMLFTSSLFLSITCFSSDIASLNSLRDLLLAIILITSLTLVLISSVAALMLGSKNSPSMVTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCW1</accession>
    <name>A0A2H5VCW1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00574</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74532">
        <property type="protein sequence ID" value="GBC74532"/>
        <property type="gene ID" value="HRbin05_00574"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024656">
        <property type="entry name" value="AmoA_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037001">
        <property type="entry name" value="NH3/CH4_mOase_suA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12942">
        <property type="entry name" value="Archaeal_AmoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="217" mass="24488" checksum="ADC14C4D1F04B3EE" modified="2018-02-28" version="1">MVWIRRTIHYLFIVVVAVNSTLLTINAGDYIFYSDWMWTSFVIFNLSQSTMLVVGAIYYLLFTGVPGTATYYATIMTIYTWVAKWAWIGGLGYPYDFMIVPVWIPSAMLLDLAYWATRRNKHAAILIGGSLLGMSMPLFNMINLLTVHDPLEMAFKYPRPTLPAYLTPIEPQVGKFYNSPVALGAGISAVISVPMAALGAKLNTWTYRWAAAWSKWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCW7</accession>
    <name>A0A2H5VCW7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease 4</fullName>
            <ecNumber evidence="2">3.1.21.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nfo</name>
        <name evidence="2" type="ORF">HRbin05_00577</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.2" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74535">
        <property type="protein sequence ID" value="GBC74535"/>
        <property type="gene ID" value="HRbin05_00577"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008833">
        <property type="term" value="F:deoxyribonuclease IV (phage-T4-induced) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="PTHR21445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="275" mass="31621" checksum="1621CA210F52825B" modified="2018-02-28" version="1">MRIYIGTQGLPATARGHGIEAGLRRLHELGLNALEVDFAHGIYLSMEESRDLGRLADELGIRLSIHAPYYINLCSEDEEVIRRSKHRILECVERGEVMHADTIAIHSAFYGKRSKEEAYAMVRAGYESIVDEMRSMGIKHVRLGAETMARRNQFGTLDEVLRLYKDLNGWVRPYVDFAHIFARNDGRIDYADVIDRLLNAGLEYINAHFTGLARKGYRYVDIHRPIGEPQFEPLALEIVRRRLDITIICESPLLELDCLRMRNILEFMSMELSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCW9</accession>
    <name>A0A2H5VCW9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74543">
        <property type="protein sequence ID" value="GBC74543"/>
        <property type="gene ID" value="HRbin05_00585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="40" mass="4425" checksum="8C3D8FDD83564DCA" modified="2018-02-28" version="1">MVVLEFMIGDIASIASMFAVLAYKRYRQAGRLVVVASGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCX1</accession>
    <name>A0A2H5VCX1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00451</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylmalonyl-CoA epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74411">
        <property type="protein sequence ID" value="GBC74411"/>
        <property type="gene ID" value="HRbin05_00451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07249">
        <property type="entry name" value="MMCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017515">
        <property type="entry name" value="MeMalonyl-CoA_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03081">
        <property type="entry name" value="metmalonyl_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="2"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="133" mass="15085" checksum="282650694C7F2DC8" modified="2018-02-28" version="1">MRIDHVAIAVNNVEEALKTFEKVLKVDRKQIMVVEHEKVKLAMLQLEDTRIELLEPLTDDSPIKKFLQERGEGIHHISICTDTLEQDVENASRNGVRIIGGIRPGSYGRKITFIHPKSMHGVLMELCEPHPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCY2</accession>
    <name>A0A2H5VCY2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alcohol dehydrogenase</fullName>
            <ecNumber evidence="5">1.1.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">adhT</name>
        <name evidence="5" type="ORF">HRbin05_00589</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.1" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74547">
        <property type="protein sequence ID" value="GBC74547"/>
        <property type="gene ID" value="HRbin05_00589"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="PKS_ER" evidence="4">
        <location>
            <begin position="8"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="350" mass="37953" checksum="3258D4EEC2F12946" modified="2018-02-28" version="1">MKAARIVKPKEPLQIEDLPVPRPRGKQVLVRVLASGVCHSDLHLWEGGYAGPRDMFMRVEDRGVRFPLTPGHEVAGIVEEVGDEVVNTGKGEKVLVYPWIGDGACPACTVGEENLCDRPRSLGIFQDGGYAEYILVPSERYLIKIDGQEPEQVASLACSGLTAYTALKNSSIRAQEFLVIVGAGGLGLIGVQIARAIAGSTIAVIDLDDKRLEEARRLGADHIINSSRSDPVKEVKDLTNGLGADAVIDFVNSSKTVAKDLDMLRKRGRLVLVGLFGGSTELNLALMPLRAYRIIGSYTGKYADLVELVALARRGMIRSVIGKRFRLEEVNDALTQLKEGKIMGRAVLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCZ5</accession>
    <name>A0A2H5VCZ5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Plastocyanin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">petE_2</name>
        <name evidence="3" type="ORF">HRbin05_00582</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74540">
        <property type="protein sequence ID" value="GBC74540"/>
        <property type="gene ID" value="HRbin05_00582"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Copper-bind" evidence="2">
        <location>
            <begin position="69"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="165" mass="18836" checksum="5D3ECCA9C8216DE7" modified="2018-02-28" version="1">MAITREQSPFVIGAIAFVLMIGVAISYYLFSYLPEINRKPTFPAEWTNPPKITEIKIVKGAFDPNQVDNFVPKRITINIGIDNKVVWINEDITAHTVTSDTNYHDHYSGPFDSTAEEHWDELPPNGYLMPGNKWEFVFVEPGEYPYHCIPHPWMQGTIVVKKPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD04</accession>
    <name>A0A2H5VD04_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0215 protein HRbin05_00618</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0215 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74576">
        <property type="protein sequence ID" value="GBC74576"/>
        <property type="gene ID" value="HRbin05_00618"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00582">
        <property type="entry name" value="UPF0215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002802">
        <property type="entry name" value="DUF99"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39518">
        <property type="entry name" value="PTHR39518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01949">
        <property type="entry name" value="DUF99"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006380">
        <property type="entry name" value="UCP006380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="191" mass="21367" checksum="F0C31123CDA3A9CC" modified="2018-02-28" version="1">MRLHVEKRAIRALGIAESFRKNSTNAVLAGVVMRSDLVIDGVAYSTTTVRGDDATDAVIGLYRALDRNDINVIMLGGVVISMYNIIDLDRLYSTLSLPIIGVTFEESEGLEEHIMRAFQGEKAEMKLEAYRRLGSREKVILKTGHHVYIRRAGTNIRVAKRALNKFLLQGAVPEPIRVARLLARAMLKYAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD12</accession>
    <name>A0A2H5VD12_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(2E,6E)-farnesyl diphosphate synthase</fullName>
            <ecNumber evidence="3">2.5.1.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00633</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.10" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000031">
        <property type="protein sequence ID" value="GBC74589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74589">
        <property type="protein sequence ID" value="GBC74589"/>
        <property type="gene ID" value="HRbin05_00633"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004337">
        <property type="term" value="F:geranyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="334" mass="36675" checksum="46E94214EBEA9B5E" modified="2018-02-28" version="1">MNVAIEQDIRDVARRVDEIITSTLKGEPYILYDAALHYITSGGKRLRPYMLVKCSELCNGSADKALYIASAMEMVHNFTLVHDDIMDGDEVRHGVPTVHRAYGLPYGILAGDLLLIYAFKTVAYYGRMAGLDDSTIVRLVDVLAKYCIVLSEGQAMDMEIASSTTIPDEEQYIAMVTKKTASLFEASCMMGAITAGADEDAVEKVAGYGRSIGIAFQLVDDLIGVVGDPKVTKKPVGNDIREGKKTLPILLALNKCDEDSRRRILSLLGSKQNIDENELLYAINLMKGMGIDREVREMAGKYADDATARLKGFKESSAKHALEHIARLIVERSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD18</accession>
    <name>A0A2H5VD18_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5679 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00627</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000031">
        <property type="protein sequence ID" value="GBC74584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74584">
        <property type="protein sequence ID" value="GBC74584"/>
        <property type="gene ID" value="HRbin05_00627"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044044">
        <property type="entry name" value="DUF5679"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18930">
        <property type="entry name" value="DUF5679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5679" evidence="1">
        <location>
            <begin position="5"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="49" mass="5479" checksum="254A9BE8A83FF6EE" modified="2018-02-28" version="1">MVEAYCVKCRKKVEMKNPTQVTMKNGRPAVKGTCPVCNTTLYRIGKSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD32</accession>
    <name>A0A2H5VD32_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00648</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74604">
        <property type="protein sequence ID" value="GBC74604"/>
        <property type="gene ID" value="HRbin05_00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="170" mass="19816" checksum="541B29388A2FA4CD" modified="2018-02-28" version="1">MDAKSKVRDIIAREVGSKSIDTKVECFACHVMYTVMRECNMDEATAADLLSQVLSEDSALNERFIQAIEYLHLYSRARALWFYSKDRVEKDAYLTMHVRNAIAEIEHEAREYGNDVVLRRLLLSYLSTYIAQVIGMDLHASTEELYYLLRKNGELEEEIKRILRKIITNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD35</accession>
    <name>A0A2H5VD35_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00646</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74602">
        <property type="protein sequence ID" value="GBC74602"/>
        <property type="gene ID" value="HRbin05_00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="3"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="218" mass="24952" checksum="8A5183DE494C8853" modified="2018-02-28" version="1">MVARIGEKAPNLKVSKWVQGLPTNIDRERDHVVLVEVFQVNCPGCFLYGLPTAIEIYRKYSKDGVRVLGLATAFEDFDKNTLENLELLVSTGRVIGETYRVLMQHGMLNPDGTLPYKIPFPIAMDMLVKNNGHVTDEMVIKYIEERIPDFHMYGDARRLLLIKRVREYLESKEYTPLTFEEYALQGTPSSIVIDRDGILRYVSFGYDEGLDNVIESLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD42</accession>
    <name>A0A2H5VD42_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative_PNPOx domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00656</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74612">
        <property type="protein sequence ID" value="GBC74612"/>
        <property type="gene ID" value="HRbin05_00656"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="1">
        <location>
            <begin position="10"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="130" mass="15575" checksum="192FB44B5AE71565" modified="2018-02-28" version="1">MHVKFSKKEIEFINKHEVCRLATCFNDRPHVVPVCYIFLNNSFYIATDYNTRKFRNISRNKNVALVIDVYKPNKAVMVEGIAEIIEHGQEFKEIYKLFYDRFEWVRREPWDEGEAPFIKVNIIKKVSWGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD48</accession>
    <name>A0A2H5VD48_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cytidylate kinase</fullName>
            <ecNumber evidence="5">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cytidine monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cmk</name>
        <name evidence="8" type="ORF">HRbin05_00659</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the cytidylate kinase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74615">
        <property type="protein sequence ID" value="GBC74615"/>
        <property type="gene ID" value="HRbin05_00659"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011892">
        <property type="entry name" value="Cyt_kin_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02173">
        <property type="entry name" value="cyt_kin_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00031231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="196" mass="22321" checksum="566D675569B59EF0" modified="2018-02-28" version="1">MGERLSIVVSGLPAVGKTTVARAIADRFNLLYYSGGDILKELAIARGYMHSGSDWWDKEHGIMFLEERESNPEFDKHVDDYLIALVKRGGVVVTSYTLPWLIDGEAIKILLKGSREKRAERMAARDSIPYEEALRIVTIRDERNKSLYKKLYNIDLCKDIDVFDFVINTDHLKAESVIDIVCNIVEHLIKYMGKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD57</accession>
    <name>A0A2H5VD57_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SpoVT-AbrB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00669</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000035">
        <property type="protein sequence ID" value="GBC74625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74625">
        <property type="protein sequence ID" value="GBC74625"/>
        <property type="gene ID" value="HRbin05_00669"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="2">
        <location>
            <begin position="47"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="120" mass="13876" checksum="3D270DCB3E50690B" modified="2018-02-28" version="1">MPNNMDDDITRYVSDEREEEEASKGEDVEENRGEVREGKGEEREYIHTVTKLGTISIPIPLRRKYGITNGSKMKFIDGEDGIRLIPLVSLRGMFGIDKENRDVVMRMLKEILEGRRMMIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD60</accession>
    <name>A0A2H5VD60_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00654</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74610">
        <property type="protein sequence ID" value="GBC74610"/>
        <property type="gene ID" value="HRbin05_00654"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="91" mass="10740" checksum="765FA537C0DA1FE5" modified="2018-02-28" version="1">MTTAFLVLYQFKSMSDEEASKASKEWGELKKSIPDGIRLIGEYIHAWGTEYNGFLIFESDDADKFLDWWPGFKDKIRWYVTKTHTIVARKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD63</accession>
    <name>A0A2H5VD63_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsL</name>
        <name evidence="2" type="synonym">rps12</name>
        <name evidence="5" type="ORF">HRbin05_00676</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 4">With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000036">
        <property type="protein sequence ID" value="GBC74632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74632">
        <property type="protein sequence ID" value="GBC74632"/>
        <property type="gene ID" value="HRbin05_00676"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03367">
        <property type="entry name" value="Ribosomal_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_A">
        <property type="entry name" value="Ribosomal_S12_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022863">
        <property type="entry name" value="Ribosomal_S12_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005680">
        <property type="entry name" value="Ribosomal_S23_euk/arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00982">
        <property type="entry name" value="uS12_E_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="145" mass="16308" checksum="308C0374C44DE53D" modified="2018-02-28" version="1">MANSPVGMFAARTLKQKRLKFRWSERRFKRRVLMLDKKADPLEGAPQARGIVLEKVGVESKQPNSAVRKCVRVQLIKNGKVVTAFCPRDGALNYIDEHDEVVIEGIGGSMGRAMGDIPGVRWKVSKVNGVSLRELVRGRKEKPRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD70</accession>
    <name>A0A2H5VD70_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Succinate--CoA ligase [GDP-forming] subunit beta</fullName>
            <ecNumber evidence="8">6.2.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">sucC</name>
        <name evidence="8" type="ORF">HRbin05_00688</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.4" evidence="8"/>
    <dbReference type="EMBL" id="BEHH01000037">
        <property type="protein sequence ID" value="GBC74644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74644">
        <property type="protein sequence ID" value="GBC74644"/>
        <property type="gene ID" value="HRbin05_00688"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004776">
        <property type="term" value="F:succinate-CoA ligase (GDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013650">
        <property type="entry name" value="ATP-grasp_succ-CoA_synth-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017866">
        <property type="entry name" value="Succ-CoA_synthase_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005809">
        <property type="entry name" value="Succ_CoA_synthase_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11815">
        <property type="entry name" value="PTHR11815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08442">
        <property type="entry name" value="ATP-grasp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001554">
        <property type="entry name" value="SucCS_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01217">
        <property type="entry name" value="SUCCINYL_COA_LIG_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="ATP-grasp" evidence="7">
        <location>
            <begin position="12"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="380" mass="41666" checksum="E9B172D41EF3858F" modified="2018-02-28" version="1">MVYVRLLEYQAKMLFKDYGIPVPRGYLATNLEEARRYARELGFPLVLKAQVRVGGRGKAGVVKICRDPDSFDDVFKEMMGKSVQGEVVKSILLEEFMPHNKELYLSIFLDRSKRSYAIIASPEGGVEIESVSNKVVHTLDIDDSNNNSSLLHDIAAYMGFNEDGNALVDIASRLIKLVDEKEAELAEINPMAVRDDGSIIALDAKVIVDDNALFRHEELRVFEEQSIEVEARRSGFSLVELDGNIAVVGNGAGLVMSTIDMLSDADGRAACFLDVGGSATLENIYKALTLVSRLSSVKAILVNLYGGIVDTSIVAKAIVSAYKDNIIQVPVFARIAGRNADIARDMLKGTKAVMFESVEEAIDNAVRAVKDVNNNNARNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD71</accession>
    <name>A0A2H5VD71_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Chlorite dismutase</fullName>
            <ecNumber evidence="4">1.13.11.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00692</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.49" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74647">
        <property type="protein sequence ID" value="GBC74647"/>
        <property type="gene ID" value="HRbin05_00692"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050587">
        <property type="term" value="F:chlorite O2-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010644">
        <property type="entry name" value="ChdC/CLD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36843">
        <property type="entry name" value="PTHR36843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06778">
        <property type="entry name" value="Chlor_dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="237" mass="27825" checksum="C4BA1549811CE61E" modified="2018-02-28" version="1">MSNVHSSIQSDAQGLEASHTFFNFSFFKVDQKWRWLNDVTKQESAKEFISILESASSDLKYRSYSLVGLREDADFMLWFASDALEKVQSVVARLYRTVLGKYITPTYVYISVLKPSTYTGKAESSFLKGEKPFKYVIVYPFIKSREWYLLPFEERRRMMEEHAMVGRKFPMVRLNTSYSFGLDDQDFMLAFETDDIYAFHELVMQLRETQVSRYVVKDTPMLVSIYKPIEEVIRDLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD78</accession>
    <name>A0A2H5VD78_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00553</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000024">
        <property type="protein sequence ID" value="GBC74511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74511">
        <property type="protein sequence ID" value="GBC74511"/>
        <property type="gene ID" value="HRbin05_00553"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="415" mass="46452" checksum="02BF285B9684945A" modified="2018-02-28" version="1">MRRLLMVMKMRNRGIMLVTVVAIGVVVTSLATIGLGFDVGESSSRRIIAIEQRWDGSITARYVKVSDLKPNSSMLFLDPFNKTMQEFYKGSNPNPVSLIRLLEKADAYEYYRLIRLPEMYGGDANDISSYRAYSIVGINMLQKCLVGYRSERQWIEDPCSGDVYRVWDGIVIYGYSMSGNITGSPNALARLRLGVDSDGYIVAFKGDDSVRGDGIPGHGRIILGKDVIDSSRAMLNAVSKHLGINLPMIDGYIPTRVDVWHRWMDNINSNMQDKQYIDYINVSYVGINSTGISRYTLSIFDLTKHPILRLEQRQESSALTILNLLGYNPESDSCRYEKSTGSTDGKYYILISRWYLTGSTGEPSCSILEHTMSVWISDDADGVGGYLIIVVGYMLSSEEMLATVKALDIKEIDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD83</accession>
    <name>A0A2H5VD83_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TFIIB-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00697</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74652">
        <property type="protein sequence ID" value="GBC74652"/>
        <property type="gene ID" value="HRbin05_00697"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="PTHR11618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="TF_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="5">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="329" mass="36813" checksum="C548F4AB085683C8" modified="2018-02-28" version="1">MVVVSQRSCPECGSSIIEDQSSGEYFCSSCGYVAMEHIPTLLPESIAREPEERLKSSRSGGHTSYAYHDLGISTEISYANKDFTGKSICSGMVEQIASIRRWHNRLRACSSRDRRLRNVLIKINEICSILSLPSIVCETSSLLYRNFENKSGAKGRSVACMAAASVYLACKRCSIVRSMDEIVEAANCVQSKKLVYRYYRMLAIEQGSDSIGIDAQTQADKKHEQHVQLTLDRYISKLSNLSRVDTRVEKLAIDIARKVEDEDHNAMIDGKAPNGLAAAYIYIAAMLLGIKILQHDISTVSKVTEVTIRNRCREILNNYRIRLLLKSAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD91</accession>
    <name>A0A2H5VD91_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00707</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000039">
        <property type="protein sequence ID" value="GBC74662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74662">
        <property type="protein sequence ID" value="GBC74662"/>
        <property type="gene ID" value="HRbin05_00707"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="417" mass="49246" checksum="DB7E3DDCA9EBF01F" modified="2018-02-28" version="1">MLVLLAGERILFQQEANLTIRYKTIRQKQEGRGIFYITNIRVAFEDYKQGIMLQVFPNNYELQAYRRVKGLMKEKLVFDIEKRQGTNTVTAIAEIEFKDKKDIQKAEEALNTLLNTARITNISSNSNGNSNIGSPIPITFNNNNYGYGTSSNYNMDMSNTITNKEEEERERRKEMPEEYRKWISDIKFTWDPDKRVRELGYIVENKQYDWGYFEVALVDIDFTLKDIQKYYGFDINRYSPDFKYKVAREAYKLIAVTPEDRNLKEKPDTNVYWVGIIENAYKDGSSELVGVNTNAMGDFEFILNPVHWYREFRNLITNWYNIEKDKPPITHYFSERDKIKKLTLASACKDFYYAILNKDFKKAEEAHKTISETYRKYDSETMFVNETGRYGLVLKYAMEMHARNIPYPIENVKKTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD99</accession>
    <name>A0A2H5VD99_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00573</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74531">
        <property type="protein sequence ID" value="GBC74531"/>
        <property type="gene ID" value="HRbin05_00573"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="86" mass="9743" checksum="EDF4FD91AD702475" modified="2018-02-28" version="1">MAKKEAPKDEIERMIGKRTEHMKALYIIGAIMAWAATAFGVWVGFTYYAWAYPFSSGMYALSVLTVIIVFGFIFIWKVAMEKPAIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDA9</accession>
    <name>A0A2H5VDA9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metalloprotease PmbA</fullName>
            <ecNumber evidence="5">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pmbA</name>
        <name evidence="5" type="ORF">HRbin05_00583</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74541">
        <property type="protein sequence ID" value="GBC74541"/>
        <property type="gene ID" value="HRbin05_00583"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="2">
        <location>
            <begin position="58"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="4">
        <location>
            <begin position="154"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="3">
        <location>
            <begin position="268"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="482" mass="51890" checksum="87C4531BBCE0769E" modified="2018-02-28" version="1">MSKGKDHGKGKRNRSIRRGLTGNDRESNNNDAYAKGVDLLDLCSLAVSEALRLGASEAEAYASRSRHITAYIESNDLKHVKIDEPLGIGIRVILNKAQGFASVNTFNPDKVRDAISTAISMARACPRDRYQRLPLPSKGSIPKLNGIYDSSIEGLGVDDVASYAHEMLNTAKGYDARVTVDSGLFESSSLEHAVSNSNGIEACERISIITWSIMGMARDGSGNVSNFDVQMGSSHGIRGVDVVSTAREFASNVVRSLNSRKVESFKGTMIVTPNAFLELMRDPLVFAINAFNVQRRVSRFARMLGKRVAADITIIDDGTYIEGIGASSFDREGVVHRRNVIVEHGILKGFIHNTYTATKAGIESTGNASGGIASPPSIDTTNLIVEAGGIGYDEMVREVKDGIIVNRFSGNVSSVDGNFSGVVKGGHMIKGGEIAYPVREMMVAGNIYAALKDISMVSKERKLVLDSLLPYIAVDNVSFTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDB9</accession>
    <name>A0A2H5VDB9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Divalent metal cation transporter MntH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mntH</name>
        <name evidence="5" type="ORF">HRbin05_00593</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74551">
        <property type="protein sequence ID" value="GBC74551"/>
        <property type="gene ID" value="HRbin05_00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="141"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="267"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="338"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="372"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="396" mass="42767" checksum="65CB43D19CEA4FAA" modified="2018-02-28" version="1">MRLLRLLRLFGPATIVSVAYMDPGNFGSNIASGSLHGLDLLWVVWMASAVAMLLQYLSGKLGIVAGRSLVDLTLSRLSSRYARVAYSIPLIAVIIATDMAEFLGIALGLHLLFAIPLHVAAGLAVIDVFILLLASEKRGRLELLIGLLVVIIGLSYVVQLYIIAPEPSVVLEKSVSITLDEGKVFLAASILGATVMPHALILHGYLTAERWNGMREKVKRHTRETIVYLAVAAMINASLQIAAYGAFYTKDIEVVDMTEAYNTLIPLYGSLAAHAFGIALLASGISSSLVSVVTGQKVFESIRGKGITQWKVRLVVRMINMVPLLIALSIGIKTIDILVYSQVVLSLLLPFVVIPLVVLVSRMGIVTYYTRLAGVIAVILIIIINIMLIASGQMVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDD8</accession>
    <name>A0A2H5VDD8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glutamine--fructose-6-phosphate transaminase (isomerizing)</fullName>
            <ecNumber evidence="2">2.6.1.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="8" type="ORF">HRbin05_00726</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000042">
        <property type="protein sequence ID" value="GBC74680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74680">
        <property type="protein sequence ID" value="GBC74680"/>
        <property type="gene ID" value="HRbin05_00726"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="6">
        <location>
            <begin position="2"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="7">
        <location>
            <begin position="306"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="7">
        <location>
            <begin position="475"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="622" mass="67961" checksum="2018084E7DE6D625" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDJ6</accession>
    <name>A0A2H5VDJ6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000035">
        <property type="protein sequence ID" value="GBC74631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74631">
        <property type="protein sequence ID" value="GBC74631"/>
        <property type="gene ID" value="HRbin05_00675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="35" mass="3613" checksum="B741DB519422FA0A" modified="2018-02-28" version="1">MPFVSSGIVANSKAVVVGSLTTGPEMVMLSRAFKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDK5</accession>
    <name>A0A2H5VDK5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000037">
        <property type="protein sequence ID" value="GBC74641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74641">
        <property type="protein sequence ID" value="GBC74641"/>
        <property type="gene ID" value="HRbin05_00685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="47" mass="5481" checksum="3EEBABACD6561F24" modified="2018-02-28" version="1">MPKRTMPICFTREQVKLLEEYAKSKGMLNLSQAVEEIIEKIEVVVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDM2</accession>
    <name>A0A2H5VDM2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transcription factor E</fullName>
            <shortName evidence="4">TFE</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">TFIIE subunit alpha homolog</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Transcription initiation factor TFIIE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tfe</name>
        <name evidence="6" type="ORF">HRbin05_00706</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.</text>
    </comment>
    <comment type="domain">
        <text evidence="4">The winged helix domain is involved in binding to DNA in the preinitiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TFE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000039">
        <property type="protein sequence ID" value="GBC74661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74661">
        <property type="protein sequence ID" value="GBC74661"/>
        <property type="gene ID" value="HRbin05_00706"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006367">
        <property type="term" value="P:transcription initiation from RNA polymerase II promoter"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01909">
        <property type="entry name" value="TFE_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016481">
        <property type="entry name" value="TF_E_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017919">
        <property type="entry name" value="TFIIE/TFIIEa_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002853">
        <property type="entry name" value="TFIIE_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024550">
        <property type="entry name" value="TFIIEa/SarR/Rpc3_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02002">
        <property type="entry name" value="TFIIE_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006373">
        <property type="entry name" value="TF_E_archaea"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00531">
        <property type="entry name" value="TFIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51344">
        <property type="entry name" value="HTH_TFE_IIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH TFE/IIEalpha-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="173" mass="20017" checksum="BF5FF06467537D3D" modified="2018-02-28" version="1">MEYEDTFVKIAHLLGGEDYVRVARALLNNEDTTDEEIASATGLKINTVRKVLYDLFSKALIIGIRVRDEKKGWFVYRWRVKRDNVDTFIDGQKRKILDRLRIRLQYEESNQFYHCGNYSCPRLTFDQAVDAFFRCPSCKAPLNLADNSMLKQAIIAKINELSSELQKNGKGNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDQ1</accession>
    <name>A0A2H5VDQ1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Acylphosphatase</fullName>
            <ecNumber evidence="1 2">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">acyP_2</name>
        <name evidence="5" type="ORF">HRbin05_00737</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="1 2"/>
    <dbReference type="EMBL" id="BEHH01000045">
        <property type="protein sequence ID" value="GBC74691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74691">
        <property type="protein sequence ID" value="GBC74691"/>
        <property type="gene ID" value="HRbin05_00737"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00112">
        <property type="entry name" value="ACYLPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00151">
        <property type="entry name" value="ACYLPHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="4">
        <location>
            <begin position="7"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="94" mass="11017" checksum="FDDAF333280F498C" modified="2018-02-28" version="1">MSLKKIRAHVYVKGKVQGVYFRQNMRNVARKYNVHGWVRNLKDGRVEAVLEGDEDAVHQVIEWCHIGPSGARVDDVDVMYEEYRGEFNSFEILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBC2</accession>
    <name>A0A2H5VBC2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73992">
        <property type="protein sequence ID" value="GBC73992"/>
        <property type="gene ID" value="HRbin05_00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC73992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="133" mass="15403" checksum="84BB762ECE79A032" modified="2018-02-28" version="1">MSELPKWAEDEINSITDSSFKLEGEWEGTGYFLDIEGKSRLVDINFYERLPNGKHIITARVSDALNMDEFRKGIVYTYRLRILKASISDRLAEYLRKNFNLNMDGVYRFELYSLEPLEDVGYEGSVGEDVGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBD0</accession>
    <name>A0A2H5VBD0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ribose-phosphate pyrophosphokinase</fullName>
            <ecNumber evidence="5">2.7.6.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prs</name>
        <name evidence="5" type="ORF">HRbin05_00030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribose-phosphate pyrophosphokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74002">
        <property type="protein sequence ID" value="GBC74002"/>
        <property type="gene ID" value="HRbin05_00030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="155"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="335" mass="35697" checksum="8C83815FCD4E7B8A" modified="2018-02-28" version="1">MGTSILAGPASKDIAKGIADTLADKDEHVRLVDVDLRVFPDGESKIRIADALDGDDVVVVQSTYPPVDTHMMQLFFILSKVSKVASRTVTVVPYLGYARQDREFLAGEIVSIDAIARIISSYAIDALITFDAHSSLALSYFTVPVHNISAVPLLAEYFKKRLEGEGVEAKDVLSISPDAGGADRAEALADMLHCNSIALRKSRDRITGAIKIDHEMLSKMRDDLKGKVAIVVDDMISTGSSVAEAVRALLEHGCKRVHVACTHALMLDGALERIKEGGAIDVVATNTVPNKVSKVVDVAPLAASAVLSILSSNSARSKVGMEGSSRSRSNSISTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBF8</accession>
    <name>A0A2H5VBF8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00049</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74018">
        <property type="protein sequence ID" value="GBC74018"/>
        <property type="gene ID" value="HRbin05_00049"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="176" mass="20607" checksum="FEFE870EAAADB378" modified="2018-02-28" version="1">MNRIGDVILHASPTTVRDEPIMLDLRFKIDGRIRDLFTRERWLDAYEHHDNLFRIKYAISIKKDGSLTSKDIVEPITFVRKASIYWSRDPTMQPYPPEKKVWVMIVADQDSILPKDEDEARSLLFDVHRRIEMMPSMLGKGRHDIFAEVSAEWGKHVYAEAEIVTARSNKVRLEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBG3</accession>
    <name>A0A2H5VBG3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00058</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74027">
        <property type="protein sequence ID" value="GBC74027"/>
        <property type="gene ID" value="HRbin05_00058"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="144" mass="16696" checksum="066E31CCD46C5436" modified="2018-02-28" version="1">MSTTLGWMVVREDIQYYIYDGSRNVIGYFTPDYGTNEEDRIIDLITDEASVRGGKLTLYITAMPSDEMNYDRFMEWMGSLDEKLTKVKAYQDKRGLGSPTVRIEHNSIAVNMDIRFDRRVELTKKSLTSALSDVLDEMHYMQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBH0</accession>
    <name>A0A2H5VBH0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribosomal RNA small subunit methyltransferase Nep1</fullName>
            <ecNumber evidence="5">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">16S rRNA (pseudouridine-N1-)-methyltransferase Nep1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nep1</name>
        <name evidence="6" type="ORF">HRbin05_00041</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a pseudouridine in 16S/18S rRNA + S-adenosyl-L-methionine = an N(1)-methylpseudouridine in 16S/18S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:46696"/>
            <dbReference type="Rhea" id="RHEA-COMP:11633"/>
            <dbReference type="Rhea" id="RHEA-COMP:11634"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74010">
        <property type="protein sequence ID" value="GBC74010"/>
        <property type="gene ID" value="HRbin05_00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070037">
        <property type="term" value="F:rRNA (pseudouridine) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18088">
        <property type="entry name" value="Nep1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00554">
        <property type="entry name" value="NEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005304">
        <property type="entry name" value="Rbsml_bgen_MeTrfase_EMG1/NEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023503">
        <property type="entry name" value="Ribosome_NEP1_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12636">
        <property type="entry name" value="PTHR12636"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03587">
        <property type="entry name" value="EMG1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="204"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate rRNA" evidence="5">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes Arg-xx" evidence="5">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate rRNA" evidence="5">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate rRNA" evidence="5">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate rRNA" evidence="5">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="229" mass="25686" checksum="BAA735BFBEBCD748" modified="2018-02-28" version="1">MMITLIIAEASLELVPEEIAWHSAVRKHAKRVGKEPKGILLDRSYHHAAMLNLKDAYRRGRPDIVHFSLLEATSIPLYHKGMLSVYVHTLADKVISVGKKDVRLPKNYNRFVGLMEDLFSKGRIESSDDRHLLLEVEDMGFNMLLDRIEPSVVIGLSRLGEMRSAEYVASVVKDLEGACIVVGGFPKGTFSTSIRNRFEHTISISKYGLEAHVVVARVLYEVEKALGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBJ7</accession>
    <name>A0A2H5VBJ7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Homoisocitrate dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.87</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hicd</name>
        <name evidence="2" type="ORF">HRbin05_00089</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.87" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74058">
        <property type="protein sequence ID" value="GBC74058"/>
        <property type="gene ID" value="HRbin05_00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047046">
        <property type="term" value="F:homoisocitrate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="1">
        <location>
            <begin position="3"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="338" mass="37148" checksum="F2A119CD5D9E36B8" modified="2018-02-28" version="1">MPKAAVIRGDGVGPELVDAMLFVLKRCNTSVELIPCEAGAEWWERHNGDSYIPESTWKILRESNACFKGPTTTIPSPKAPRSVAVTLRQTFDLYANIRPIKTYERSARQLDFICVREATEGLYAGIEFKIGDDAAIAIRKITRKGCERIAKKAGEIAVEKGYSKVIAITKRNILKETDGIFIDAVTSICSSKGLQVEEYYIDNMCQQLVKNPERFNGCVLVSTNLFMDVVSETASAHLGSIGNVYSANLGDSYAMFEPAHGSAPKYKGLNKMNPTATILSGAWMLEYLGEKDIAKAIFDATRDVINEGRYVTYDLGGNATTSKMAEEIAARAVKMLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBJ9</accession>
    <name>A0A2H5VBJ9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-reducing hydrogenase HoxS subunit delta</fullName>
            <ecNumber evidence="3">1.12.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hoxY</name>
        <name evidence="3" type="ORF">HRbin05_00097</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.12.1.2" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74066">
        <property type="protein sequence ID" value="GBC74066"/>
        <property type="gene ID" value="HRbin05_00097"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047985">
        <property type="term" value="F:hydrogen dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037024">
        <property type="entry name" value="NiFe_Hase_small_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0371">Homeobox</keyword>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="2">
        <location>
            <begin position="23"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="270" mass="29937" checksum="D9F9BB90873BD276" modified="2018-02-28" version="1">MRRGSNSSRRKRPKLAVWKFASCDGCQLSILDLEDELLELVDSVEVAYFLEASKAVIKGPYDISLVEGSITTADDVERIRRVRSVSRYLISIGACATSGGIQALRNFKDVKEFTSIVYARPEYISTLERSTPISEHVKVDLELHGCPVNKYQLLEVISSLLNGKRPNINSYSVCMECKRAGNVCVMVAYGMPCMGPVTRAGCNAICPSYKRGCYSCFGPSESANIGALSKRFKDLGVDDESIVRMFRMFNAYAQGFKDVEEKVMGVNSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBK5</accession>
    <name>A0A2H5VBK5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00081</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74050">
        <property type="protein sequence ID" value="GBC74050"/>
        <property type="gene ID" value="HRbin05_00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="234" mass="26163" checksum="59075A5A2DC025DA" modified="2018-02-28" version="1">MYDSRLDEWFVPKFGPLRFRVAIGMLFLPYTGMCVSFAVIGSLLAGNIIWDRLIAIVLIYLLALGVSAHALDSIGSKRKPWGNVFSNRTLLAIAITALAVAYTIGIYYIVLYVPFLAIIAVLEGFFLFAYNVELFNGRFHSNLWFSISWGGLPLLAGYVMQTNSISISALIASSITALVAYAEIRVSRPYKELKRSHMDEKEKKIILYERMLKLMSIGSIGVAISMLMVRMLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBL2</accession>
    <name>A0A2H5VBL2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00104</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74073">
        <property type="protein sequence ID" value="GBC74073"/>
        <property type="gene ID" value="HRbin05_00104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="133" mass="15206" checksum="782C291035915874" modified="2018-02-28" version="1">MDNMVYDMMSASISMQDKGSNNIKRARDAVDMLKRRIELRSSMLDTLADNNLKASINSIRHAPQLSKKISRIGWMLFWIPEPTMVSTAVGIPMILAGKALERYYNSLTVKGLYEETSRMLKSLEQLTQDNLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBL4</accession>
    <name>A0A2H5VBL4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TGS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74060">
        <property type="protein sequence ID" value="GBC74060"/>
        <property type="gene ID" value="HRbin05_00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045001">
        <property type="entry name" value="DRG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43127">
        <property type="entry name" value="PTHR43127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGS" evidence="2">
        <location>
            <begin position="283"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="354" mass="40207" checksum="0C0410C5227EC82A" modified="2018-02-28" version="1">MVTNLTQEAKAKWAEAIAAKDPELKLRLLKEFYSLMPKHKATEKLEMSIKRQIAALEEEVEQRRSRKRGSTRQEWTVKKEGSLQVALVGTINSSLNLFERLTGLSVSIYDALMRPRIGVFSALNIRAQMVLTPLDYMIGEDRLDKFISIARNADAIMVVVDSSKYMDDVCKWFEARSINILARSRAEIEYTPHGGIRIVGRSDYVDEGSVFNLIKSYGIKNVIVRLYSNTTLEDVEDAIFGRISKDAVFVAFADNVCDVNGIDLIRFNGDKDSLMLDLLKHIGLIRVFTKKVGSDPVDEPLLMHRGSKVIELAERIHRDFARAFKYARVWRHGSIIKVGKDFILDDLDVVELHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBL6</accession>
    <name>A0A2H5VBL6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dihydroanticapsin 7-dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.385</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">bacC</name>
        <name evidence="1" type="ORF">HRbin05_00118</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.385" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74086">
        <property type="protein sequence ID" value="GBC74086"/>
        <property type="gene ID" value="HRbin05_00118"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="248" mass="27187" checksum="21547D496AFA6E56" modified="2018-02-28" version="1">MILKDKIALVTGASRGIGEATARVFAKNGAKVAMLARDFERLRSVASSIDGDTLPIKADVTDEKDVQAAVNTVLKKYDRIDVLVNNVGYINDPTPFHMMHDEDWDMLININLVSTLRMTRAVLPIMMNQKNGCIINISSVAGIKAYRIPLSVYNTVKAGVIMFTKSIALEYAQYNIRCNCICPGTVRSKFLEPYLEDAEAREELSKLQPLGSIGEPEDVANAILYLASDSARWVTGTMLIIDGGLSIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBL7</accession>
    <name>A0A2H5VBL7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="2">5.1.3.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">galE1</name>
        <name evidence="2" type="ORF">HRbin05_00125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74092">
        <property type="protein sequence ID" value="GBC74092"/>
        <property type="gene ID" value="HRbin05_00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="322" mass="36281" checksum="FE2986E9AA65B595" modified="2018-02-28" version="1">MHDTYLVNSNILVTGGAGFIGSHLVDRLLADNINVDVIDNLSTGNIEHVNRWSNRYSGFKFFRLDLVTDSLDTLNNDYSIIFHLAANPDVRSSSINPRLHFEQNILATFNILEYARKHDINTFVFTSSSTVYGEPEVIPTPENTPLHPISMYGASKAACEALICSYAHMYGIKSVIYRLANVIGARSTHGIIYDFIRKLQKDKNALEILGNGKQKKSYVHVSDCIDGMLIGLKNNSIVSVFNVGSDDYVDVLTIAESTVNILGLNNVKFRFIDNYDGRGWKGDVRVMLLDTSRLKSLGWKIRYNSKEAIEETIREWLLKNHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBM3</accession>
    <name>A0A2H5VBM3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenine phosphoribosyltransferase</fullName>
            <shortName evidence="10">APRT</shortName>
            <ecNumber evidence="5 10">2.4.2.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">apt</name>
        <name evidence="12" type="ORF">HRbin05_00120</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine</text>
            <dbReference type="Rhea" id="RHEA:16609"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.4.2.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from adenine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="5 10"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74087">
        <property type="protein sequence ID" value="GBC74087"/>
        <property type="gene ID" value="HRbin05_00120"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00646"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006168">
        <property type="term" value="P:adenine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00004">
        <property type="entry name" value="Aden_phosphoribosyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005764">
        <property type="entry name" value="Ade_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01090">
        <property type="entry name" value="apt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="11">
        <location>
            <begin position="41"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GBC74087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="172" mass="19026" checksum="48D14C95C407A256" modified="2018-02-28" version="1">MNLKAMIMEFPDFPKKGVLFRDISPLLKSATTMNYIVERFYEHFKHKKINTIAGIESRGFIVATALAIRFGCSMVMIRKQGKLPGRTRSIEYTIEYGKATMEIQEDAVSPGDRVLIADDLIATGGTAVAAARLVEGLGAEVAGFAFIVELARLRGRELLKGYDVCSLVVYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBN9</accession>
    <name>A0A2H5VBN9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aspartate--tRNA(Asp/Asn) ligase</fullName>
            <ecNumber evidence="4">6.1.1.23</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">aspS2</name>
        <name evidence="4" type="ORF">HRbin05_00138</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.23" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74105">
        <property type="protein sequence ID" value="GBC74105"/>
        <property type="gene ID" value="HRbin05_00138"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050560">
        <property type="term" value="F:aspartate-tRNA(Asn) ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="PTHR43450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="3">
        <location>
            <begin position="1"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="269" mass="30634" checksum="F053B34E079F9615" modified="2018-02-28" version="1">MISTASEGGAALFPIFYFDREAFLAQSPQLYKEQLTLAFEKVYEIAPIFRAEPSRTNRHLAEAISIDVEHAFVNYEDVMGILEEMISHAIGYVVDKCKDEFSILGTTPIKPSTPFPRYRYSQLIDILKGEGIRIEWGDDFAAEHLKALSSMLKGYYFIVDWPARMRPFYTKTKDDGSTALSESFDLMHGDLEISSGSTRINRKDELMERLKMQGLKPESFAHHLIVFDYGMPPHAGFGLGLERLLMTVTGLENIRDATFYPRDIDRLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBP0</accession>
    <name>A0A2H5VBP0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00137</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74104">
        <property type="protein sequence ID" value="GBC74104"/>
        <property type="gene ID" value="HRbin05_00137"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="174" mass="19015" checksum="3402FD4118ABCCDE" modified="2018-02-28" version="1">MNHASLATVVLVVVLGITVNEIYAAPFEQDIIVTPSNIHASERVTITCFNEPAHPAGVNGVLEIEDPAGNSYAIGSTFSVGDFNNNGIPDNSLTVVFPDDFNASIMHGKYMVFCQFWSGECECVEPGEMDEINKAFWQFFYVSFNVLPESSIGVIGLIGSSAIASWLFYNKYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBP7</accession>
    <name>A0A2H5VBP7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminodeoxychorismate synthase component 2</fullName>
            <ecNumber evidence="2">2.6.1.85</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pabA</name>
        <name evidence="2" type="ORF">HRbin05_00155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.85" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74122">
        <property type="protein sequence ID" value="GBC74122"/>
        <property type="gene ID" value="HRbin05_00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046820">
        <property type="term" value="F:4-amino-4-deoxychorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="201" mass="22281" checksum="97DF62B7A3239308" modified="2018-02-28" version="1">MRIIIIDNYDSFTYNLAQQIGSMANVMNIGIEPLVFRNDKITLGEILMLDPDAIIISPGPGHPANRRDFGVSADVILNMYDKLPILGVCLGHQGIVHLFGGKVVRAKTPRHGKTSMISHNSKDLFQSIDNPFKATRYHSLVADPSTIPPSLEVTAYALDDGEVMGVRHKEHMLFGVQFHPESILTKSGDIIMINFISMVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBP8</accession>
    <name>A0A2H5VBP8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nadK_1</name>
        <name evidence="5" type="synonym">nadK</name>
        <name evidence="7" type="ORF">HRbin05_00147</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74114">
        <property type="protein sequence ID" value="GBC74114"/>
        <property type="gene ID" value="HRbin05_00147"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH marR-type" evidence="6">
        <location>
            <begin position="271"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="128"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="169"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="337" mass="37798" checksum="1E511F5BCEFA361C" modified="2018-02-28" version="1">MHVSLVAFEQQKGEGDGMLQSILNTLSSMNVKVDILSNIEQSRCSIDSDLVLVMGGDKGILQYFHKLAVDSPPVLGIYEEDSTGFLAQVDVRDIAKVMGMISSNRYRVEEVTRLAVRVDGMEMEPVLNDVALFPSKSATLMEYRLRINGDDVWHDKSDGVIISTPIGSTAYSMSAGGPMVLRSARVFLIVPVNSMDVTRRPLIVNDDVEIEVSDIISRYRCEVILDGGRRVTIRRALNCYKYPYPARFVRLEGYTPASLLAKKVKLAEDMLGMPPSAKLVLKTLEYEGPMSQRDLIARTMLPARTLRLALNHLIQKGYVRRRASLRDARQKIYELRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBR5</accession>
    <name>A0A2H5VBR5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00166</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74133">
        <property type="protein sequence ID" value="GBC74133"/>
        <property type="gene ID" value="HRbin05_00166"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="229" mass="25728" checksum="E0275468F5098924" modified="2018-02-28" version="1">MGISRLLLLRIIPYMDGLISMDELSSQTGISISVCNAMLNELVSNSIGSMEGEGYVRFTHMDKISAVVLAMRLNASMDEVARVLHWKDFEMLAAEILKANGYSTARNVRVRARLGLARGSRTMMEVDVVGLKYVDCRNTALLIDCKHWHYISTSELARVCEKQVIRARAFIAERMDVDDAIPAVVVLNDTPSLIDGVPIVPITRFREFLNELYSIIDDLHVVRRLELEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBR6</accession>
    <name>A0A2H5VBR6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">dCTP deaminase</fullName>
            <ecNumber evidence="2">3.5.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">dcd</name>
        <name evidence="2" type="ORF">HRbin05_00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.13" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74127">
        <property type="protein sequence ID" value="GBC74127"/>
        <property type="gene ID" value="HRbin05_00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="176" mass="20328" checksum="527178D85846039D" modified="2018-02-28" version="1">MAVIGKDELTRLIERYKCIHPFNPMLLDGDGYILTVKDDVTLNYLEHKNVISYEVVFTPPNYVAHLTAKSRYGRLGLSFLNAAKVHSGFVGRIVLEVVNLNNERKPITIRHGDPFMHIEFIERIGKPSPYEGEYQFQYMSDEEVSIYLSVLKEFGSVFNLERLERIAARRVMQTSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBS4</accession>
    <name>A0A2H5VBS4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00172</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74139">
        <property type="protein sequence ID" value="GBC74139"/>
        <property type="gene ID" value="HRbin05_00172"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="80" mass="9295" checksum="2B4D036EB405A748" modified="2018-02-28" version="1">MNGLDYIISESNIFKRNKVPLEDIVLAALLHYSGLSLRAYLMEGYHMKLLGNGWYHALKSILKEPEKYRRIITVDKQDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBS7</accession>
    <name>A0A2H5VBS7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cob(I)yrinic acid a,c-diamide adenosyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yvqK</name>
        <name evidence="5" type="ORF">HRbin05_00186</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74152">
        <property type="protein sequence ID" value="GBC74152"/>
        <property type="gene ID" value="HRbin05_00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="4">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="183" mass="20135" checksum="9C6834B427746E50" modified="2018-02-28" version="1">MAKIYTRGGDKGYTSLLGGKRVSKAALRVEAYGNIDELNSAIGLCISFIDEEDVKVVLEGVQNDLFIAGAELADPDMSESTPKVSIEMVKKLEEVIDRYEEEAGSIAYFILPGGSREASLLHLARAIARRAERAIVALKDDGGNVSDDLIAYMNRLSSLLFILARVMNRRKGVEDVPWKNKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBW0</accession>
    <name>A0A2H5VBW0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00183</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74150">
        <property type="protein sequence ID" value="GBC74150"/>
        <property type="gene ID" value="HRbin05_00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="126" mass="14779" checksum="0EBF1AC3BC352EF5" modified="2018-02-28" version="1">MVINFHVDSDDPAGLSFKIQRCLRCFDFIVLKPADGFVDRCPYCGTLQIPYFYSLMNGKSNTRLEEHSKRLLDDSDLRLREDLLLSLRIWQFKIRNGIDQHGEIPEFFQSIRREKLNAIPISDEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBW3</accession>
    <name>A0A2H5VBW3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acylphosphatase</fullName>
            <ecNumber evidence="1">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">acyP_1</name>
        <name evidence="5" type="ORF">HRbin05_00212</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74178">
        <property type="protein sequence ID" value="GBC74178"/>
        <property type="gene ID" value="HRbin05_00212"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="165"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="251" mass="29188" checksum="2048F108D1A153D8" modified="2018-02-28" version="1">MLAYKLIVRGRVQRVGFRRYVLEHARALGLKGNVRNEDDDSVHIHAQADDEDVLKRFIELIKSAPSPAYVASVEIIPAEVEDLKSFKIVYGELGDELQEGFGAMQSVFDDYRQEFRSYVGEFRSYVGEFRSYVGEFREFASRTDTNFAELKQEIRAFSDRTDANFAELKQEVRGVRDDLKQEIRAFSDRTDLNFKAIEAKYGEISEKLTLILNELKRSNEETRADLTRAMNILADILNRLIRLEEQREQRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBW5</accession>
    <name>A0A2H5VBW5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00217</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74183">
        <property type="protein sequence ID" value="GBC74183"/>
        <property type="gene ID" value="HRbin05_00217"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="146" mass="16005" checksum="2E42F44F6C419C4A" modified="2018-02-28" version="1">MGIGVVVDNNNTLAYLETLCKRAEMNLALIVAGDDDIDLSIKGKSNTIYILELDTGSSVAGGRVGGFGSRRFKMIHLFRLEDGRCVKMKSIKLEGDYDDEEEIDAVVAGGYVVRLPIRLSDGREVMASCLIDQYAVRLLNSRFGIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBX2</accession>
    <name>A0A2H5VBX2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00194</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74160">
        <property type="protein sequence ID" value="GBC74160"/>
        <property type="gene ID" value="HRbin05_00194"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="418" mass="49516" checksum="B4216DC45F90A972" modified="2018-02-28" version="1">MLVLLAGERILFQQEANLTIRYKTIRQKQEGRGILYITNLRVVFEDYKQGIMLQVFPNNYELQAYRRVKGLMKEKLVFDIEKNQTTALVEVEFKDKDKNKKNTLRETEEALNTLLNTARITNISSNSNGNSNIGSPIPITFNNNNYDYGTSSNYNMDMSNNTITNKEEEKERMKEMPEEYRKWISDIKFTWNPDKRVRELGYIVENKQYDWGYFEAALVWIDNDLENMQKYYGFDINRYSPDFRYKVAREAYKLSAVTPEDRNLKEKPDTNVYWVGIIENAYKDGSSELVGVNTNARGDFEFILNPVHWYRKFRSLVTHWYDIERDKPPITHYTSERDKIRKLTLASACKDFYYAILNKDFKKAEEAHKIISETYRKYDSETMFVNETGRYGLVLKYAMEMHVRNIPYPIPEGKKTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBX5</accession>
    <name>A0A2H5VBX5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TRASH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00113</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic ribosomal protein eL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74081">
        <property type="protein sequence ID" value="GBC74081"/>
        <property type="gene ID" value="HRbin05_00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038630">
        <property type="entry name" value="L24e/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000988">
        <property type="entry name" value="Ribosomal_L24e-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01246">
        <property type="entry name" value="Ribosomal_L24e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TRASH" evidence="3">
        <location>
            <begin position="10"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="69" mass="7941" checksum="374F959E49F49860" modified="2018-02-28" version="1">MSVSLSSKSCSFCGNTIRFGEGRILVRNDGSMLYFCSSKCWKNMLVLKRDARKLKWTRRYVKGGIKVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBY6</accession>
    <name>A0A2H5VBY6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00231</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74197">
        <property type="protein sequence ID" value="GBC74197"/>
        <property type="gene ID" value="HRbin05_00231"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090529">
        <property type="term" value="P:cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007561">
        <property type="entry name" value="Cell_div_SepF/SepF-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038594">
        <property type="entry name" value="SepF-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04472">
        <property type="entry name" value="SepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="97" mass="11403" checksum="258B7215BFECF7BB" modified="2018-02-28" version="1">MQKEREVSLYLKTVTLRDANDLDAILDDIRHNNILIIRVTPLAQKSLEDLKMVVEELYKFVRSIHGDIARLGEERLVITPPGVRIWKNMYESLKEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC01</accession>
    <name>A0A2H5VC01_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pantoate kinase</fullName>
            <shortName evidence="5">PoK</shortName>
            <ecNumber evidence="5">2.7.1.169</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">thrB_2</name>
        <name evidence="7" type="ORF">HRbin05_00224</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(R)-pantoate + ATP = (R)-4-phosphopantoate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28246"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61294"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; coenzyme A biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GHMP kinase family. PoK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.169" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74190">
        <property type="protein sequence ID" value="GBC74190"/>
        <property type="gene ID" value="HRbin05_00224"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02223">
        <property type="entry name" value="Pantoate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012043">
        <property type="entry name" value="PoK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42282">
        <property type="entry name" value="PTHR42282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016896">
        <property type="entry name" value="GHMP_arc_MJ0969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="3 5 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="6">
        <location>
            <begin position="102"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="326" mass="35402" checksum="5B31E78F3A4BA7E1" modified="2018-02-28" version="1">MMTMMDGYAKAIAFAPGHITGFVEFPTPMLDDPLLKGSRGAGVCISKGITTEVHLYPYDGLEAPEIKISINGKPCSDADVSLYVVKEYLRLVDIRRFKLDIMHRADIPIGYGLGSSGAAALSLSYALNRAFMLNLSNEEAARIAHKADLACRCGAGTVIAEYHGGLEMRLKAGAPGIGIVESIIDEVDDYKVLMLCISPYSTKEFLTNRIGMINGLGGKMLNILKESRSVETFLDLSFRFARSIDFITDRAARVIDALHCIGCKASVALFGETVFTIVSNDKVGEVEKVLSCYRDLYSNSSSSVCYLSCSIDTRGATVIEDTREPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC02</accession>
    <name>A0A2H5VC02_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00249</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74214">
        <property type="protein sequence ID" value="GBC74214"/>
        <property type="gene ID" value="HRbin05_00249"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="196" mass="21369" checksum="F2746A5A38CB2B34" modified="2018-02-28" version="1">MAATIKAMRVELDVSNVTSIDQARAYVEEIQHQYADLTVTNINVTANRITFDVGSPGMEDLSPSDIKFRIEEFLNMNVAPFAVNRINIGGAVTVTLEAARAAASTTTAAALKKIVTIELDVSNVASVDQARAYVEEIQHQYADLTVTNINVTANRITFDVGSPGMEDLSPSDIKFRIEEFLNMNVAPFTVKSVNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC07</accession>
    <name>A0A2H5VC07_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tubulin-like protein CetZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cetZ</name>
        <name evidence="3" type="ORF">HRbin05_00260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74225">
        <property type="protein sequence ID" value="GBC74225"/>
        <property type="gene ID" value="HRbin05_00260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin" evidence="2">
        <location>
            <begin position="6"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="339"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="431" mass="46868" checksum="364DB59B206A6FA5" modified="2018-02-28" version="1">MELPLPAMIIGIGGAGTKIAMMMRDVSALDTLLISSSANDLAITSMSMDKRRKVSKYDDGGGAASLSDGAKEPRMERMLIETGMLNPSPYTIRGSLLAYKDRIRERLMGYNTFIMVANLAGRNGVAVAPLLADMIKADHDDDYATASSSNDNNSKKKKKKARLISFVIMPFSFEHDKLFKAGIALKKLSERSDCTIVIDNDSFLENNQDLSIDECYRIANGMLLEVFNIIMMNSEVDGLNILSAGIDSRVDVAVKNAVSMLYSNTKPDKVRSALLYIFDGSTEGISIGLIDALAKSISSILVGRHGEYAVVRVSTKGRSRMMHVDGENDDDYEGIDNDNNNHHSSIGSSSISNSNSSSSNASGTKVGADDSKESDDGVHSTILLSKVTGLSKLDSYDPLSILPRECLLDWEYDESEMRLNIDSLVALPNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC11</accession>
    <name>A0A2H5VC11_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA-t(6)A37 methylthiotransferase</fullName>
            <ecNumber evidence="6">2.8.4.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">miaB</name>
        <name evidence="9" type="ORF">HRbin05_00259</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[sulfur carrier]-SH + AH2 + N(6)-L-threonylcarbamoyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-L-threonylcarbamoyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37075"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="Rhea" id="RHEA-COMP:11092"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:74420"/>
            <dbReference type="EC" id="2.8.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methylthiotransferase family. CDKAL1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.5" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74224">
        <property type="protein sequence ID" value="GBC74224"/>
        <property type="gene ID" value="HRbin05_00259"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035598">
        <property type="term" value="F:N6-threonylcarbomyladenosine methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061712">
        <property type="term" value="F:tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006466">
        <property type="entry name" value="MiaB-like_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01578">
        <property type="entry name" value="MiaB-like-B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="7">
        <location>
            <begin position="8"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="136"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU368081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="454" mass="50298" checksum="1767D69DAB3FE457" modified="2018-02-28" version="1">MIGVNVMVKVWLEVYGCSSSLSDGEIIAGIIAGKGYELASNFDEADASIIVTCVVKDATANRMVERIKRLSSKPLVVAGCMAKAEPNRIRRFSPRASIVGPNAIDRVDTALASALDGKGIILLDGSVQKVGLPKIRVNPVISMVQIGSGCLSECTFCETRIAKGRLTSYRIGDIVRQVREDVEQGCREVWLTSTDNGAYGRDIGTNLAELIKAVCSIDAEFMIRVGMMNPQYLPSMLDDLIEAYRDDKVFKFIHIPVQSGSDRVLRLMRRGHRASTFIDMVKRFRRELKLCTIATDIIVGFPSESEEDFNASIDLLLEVEPDVVNVSKYSARPGTEASRMEQLSKQVINERSRVMHDVVSRVCYSRNLAWKGWEGAVLVDELTDTGGVQGRNFAYKPIYLIKKGIVDNNYDSYSKGHNSFNNDGVNNAMRLLGSWVRVRIDRVTTHSLLGSIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC13</accession>
    <name>A0A2H5VC13_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00263</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74228">
        <property type="protein sequence ID" value="GBC74228"/>
        <property type="gene ID" value="HRbin05_00263"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="32" mass="3616" checksum="6E0396D298674A1D" modified="2018-02-28" version="1">MHGEGYLRYMEGNSIGSVQLYTYVDNKGGNYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC17</accession>
    <name>A0A2H5VC17_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74235">
        <property type="protein sequence ID" value="GBC74235"/>
        <property type="gene ID" value="HRbin05_00270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="354" mass="39252" checksum="473DF3FABCC23927" modified="2018-02-28" version="1">MHKRKILALSLLSMLAISVMPSALAFQIREAQVFTPQNEVGVEFLSVRVSTIEHPQGGKLKDMLSGVNERIIFRANDSTPGIEVLKEKINEGLLEAGSPAKVKEVKEVIYNVALQDDGMKVTMQQSLTLKLLLTGIVIQEAVYEQPAIIDLNWRGFKVNGQVPITLNADGTTVNMDINTMRGYLEVKYPEVISLLSRDSKFSEMLNDPLINYERIRELPITQWHKLTNALQSMAEAEKWGVKEPAPAVTVVSAGEGSLREGQHPPRVLSAQATIDGSTYYMTIQDPPISATLDIYYWAEPIRDEHGDAARVYLTEPQGQLQQSSTGNFPLMVLLAFAGMMGAIAGFVIWRANRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC42</accession>
    <name>A0A2H5VC42_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00289</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74254">
        <property type="protein sequence ID" value="GBC74254"/>
        <property type="gene ID" value="HRbin05_00289"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="178" mass="18843" checksum="8F3972AE7D8D98CA" modified="2018-02-28" version="1">MKYIALIGVIVAVVGGVIVSSLYLSTANIVQAQDGGHMAHHAVLQVDIDRVYAPFGQPGFFKLLADFTDMQVMHGHVAISNVNCDTNGKSPFVAVIANANVGAGNTQLHIIPLDSSNLVNDVSFPGKYCTYHVDIHAGMGSIEFPITDIALANSSNSAQRPHSTASATIHAEIVKMMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC48</accession>
    <name>A0A2H5VC48_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TRASH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00304</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74269">
        <property type="protein sequence ID" value="GBC74269"/>
        <property type="gene ID" value="HRbin05_00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011017">
        <property type="entry name" value="TRASH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007029">
        <property type="entry name" value="YHS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04945">
        <property type="entry name" value="YHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00746">
        <property type="entry name" value="TRASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRASH" evidence="1">
        <location>
            <begin position="5"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="47" mass="5553" checksum="DB915C34D94FA10C" modified="2018-02-28" version="1">MRVLDPVCGIEMDDDLAVKAEYEGKVYYFCCDGCRKIFLKNPKKYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC76</accession>
    <name>A0A2H5VC76_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsQ</name>
        <name evidence="2" type="synonym">rps17</name>
        <name evidence="4" type="ORF">HRbin05_00333</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74295">
        <property type="protein sequence ID" value="GBC74295"/>
        <property type="gene ID" value="HRbin05_00333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_A">
        <property type="entry name" value="Ribosomal_S17_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028333">
        <property type="entry name" value="Ribosomal_S17_arc-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019978">
        <property type="entry name" value="Ribosomal_S17_archaeal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_S17_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03630">
        <property type="entry name" value="uS17_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="131" mass="14933" checksum="51E8C4AB92CDBD07" modified="2018-02-28" version="1">MVEGDASTNISSSSSNSNSKARSIGLEVTLPARSCNDLKCPFHGRLSIRGRLLTGIVVSKKAKKMVVIERYYQQYIKKYKRYERRRSKIHAYMPECIDVEEGDEVLIGECRPLSKTVAFALLEVRKKRHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC85</accession>
    <name>A0A2H5VC85_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rpsC</name>
        <name evidence="6" type="synonym">rps3</name>
        <name evidence="9" type="ORF">HRbin05_00336</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Binds the lower part of the 30S subunit head.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74298">
        <property type="protein sequence ID" value="GBC74298"/>
        <property type="gene ID" value="HRbin05_00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_A">
        <property type="entry name" value="Ribosomal_S3_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027488">
        <property type="entry name" value="Ribosomal_S3_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005703">
        <property type="entry name" value="Ribosomal_S3_euk/arc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01008">
        <property type="entry name" value="uS3_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="8">
        <location>
            <begin position="24"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="235" mass="26029" checksum="40BED0046E4BA13E" modified="2018-02-28" version="1">MGMSKQEYSSTKAIMKNFFRNSELDEFLEKELAHAGYGGAEIQKTPLGTRITVYVTRPGLIIGRKGFGIKELTSKLEKEFGLENPQISVLEIEVPELNPRIIANRVAQMISKGTAFRRAALWALNTIMDAGAMGAEVVISGKLRSERASFEKYTAGILPKSGEPAERAVKEAVAHVLLKMGLYGIHIKIAYKDALPAEFELRDSGDVSKVEVEQDLNVQEKKMVAEEKEREGDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC93</accession>
    <name>A0A2H5VC93_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TrmB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00351</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74313">
        <property type="protein sequence ID" value="GBC74313"/>
        <property type="gene ID" value="HRbin05_00351"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002831">
        <property type="entry name" value="Tscrpt_reg_TrmB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01978">
        <property type="entry name" value="TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="TrmB" evidence="3">
        <location>
            <begin position="176"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="242" mass="27609" checksum="44E2F66BF56164D0" modified="2018-02-28" version="1">MSISMGVSVEDVMFMLISYIAGMIVTSLMINKDRYSNRISHNPYEAYEHVIADLMARIDVIDLRVKRIYSITESLYNVSHHMEGNYDYYGRVDEVERDNSTSSDDYKGSPSMAKAVDDDDGSDADASREGRSGMNGKLMIISSYHDANDDVAMKEEGKGDSSYRNINNSTIEKILSIIQEGPKTSREIEKRLGMSREHTARLMKRLYEMGYVIRDESKRPYKYILAQTDDAKKVTNYKQIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCA0</accession>
    <name>A0A2H5VCA0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S14 type Z</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps14</name>
        <name evidence="4" type="ORF">HRbin05_00328</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Binds 16S rRNA, required for the assembly of 30S particles.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74290">
        <property type="protein sequence ID" value="GBC74290"/>
        <property type="gene ID" value="HRbin05_00328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01364_A">
        <property type="entry name" value="Ribosomal_S14_2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039744">
        <property type="entry name" value="40S_S29/30S_S14z"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023676">
        <property type="entry name" value="Ribosomal_S14_type-Z_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12010">
        <property type="entry name" value="PTHR12010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="59" mass="7127" checksum="1DEC3F06DA4D92CE" modified="2018-02-28" version="1">MAKVRDFALTGRKERKYGKGSRWCRRCGQYTAIIQKYDLLLCRQCFREVAKRIGFKKYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCA6</accession>
    <name>A0A2H5VCA6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74314">
        <property type="protein sequence ID" value="GBC74314"/>
        <property type="gene ID" value="HRbin05_00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="127" mass="14931" checksum="458885352FAE6219" modified="2018-02-28" version="1">MARKKVKIELEDSEGSKYSIVVEGNLTREKVLKVFEMMNLLDDSSNEKYDAEEPNSLGERIMHLIEEEFPYGEFTSSQVLEAYEDRYNEPIKLSMVSTYLARFTSKGILARNRSGREWRYKRVLLKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCB2</accession>
    <name>A0A2H5VCB2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable chemoreceptor glutamine deamidase CheD</fullName>
            <ecNumber evidence="3">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">cheD</name>
        <name evidence="4" type="ORF">HRbin05_00370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CheD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.44" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74332">
        <property type="protein sequence ID" value="GBC74332"/>
        <property type="gene ID" value="HRbin05_00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16352">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01440">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038592">
        <property type="entry name" value="CheD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005659">
        <property type="entry name" value="Chemorcpt_Glu_NH3ase_CheD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35147">
        <property type="entry name" value="PTHR35147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03975">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="2 3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="176" mass="19112" checksum="7B6C7325EBF1A5C5" modified="2018-02-28" version="1">MGLTGTVSSNRSNTTIHVKIGELAVSKDLPLTTIVGSCIACCIYDDKSKIAGMAHIMLPTKKRKDNSDNNNTRDDTKAKYADTGIKNLIDELIKQGANINNLKAKIVGGARVFTHESGEDIFNIGERNAEKVKEVLKSYRISIVAEDIGGRGGRNVTFDPSTLTVRVKSNGYEKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCB6</accession>
    <name>A0A2H5VCB6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">18 kDa heat shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00366</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74328">
        <property type="protein sequence ID" value="GBC74328"/>
        <property type="gene ID" value="HRbin05_00366"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="21"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="123" mass="14088" checksum="3B32D59750697C72" modified="2018-02-28" version="1">MGIAEYVVRELMREFTSKTREFYEFVMPPVDIYEDGSDLVVVADMPGFKKEDIVVRVSGNILSVRATRDRPEPTGIVYWQQRPLKIDKKIPLPFSVAEEDVKATYKEGLLEIRVPLKGAVKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCB9</accession>
    <name>A0A2H5VCB9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00256</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74221">
        <property type="protein sequence ID" value="GBC74221"/>
        <property type="gene ID" value="HRbin05_00256"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="289" mass="31959" checksum="04DF20584C900BC0" modified="2018-02-28" version="1">MKTLTYMVMVYALLLPSIGYTYAQKVFEQGISITEINGSYSITCFSEPVHPSGVNGDITIIADRPYSRTLTFTPGDSNYNGVEDNSATLIFPDDFNANYTQDFTVLCNMWSGSDRDEEGAYSSITAEFWQSIYTDGSVRFRQGLIMPESIHPGGSIDIVCFSEPAHGTNTVDGIIIVKIPDERTYFKSREFIKGDIDGNGVSDDYTILRFPDDFTSYPPADTNTMGEYTVFCDLTNGTRDAGGVVLHTGEFLQAFWVSFHVIPEGIVGTLLLLCSSIMVLVLYGRRVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCD7</accession>
    <name>A0A2H5VCD7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific)</fullName>
            <ecNumber evidence="2">2.5.1.89</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Undecaprenyl diphosphate synthase</fullName>
            <shortName evidence="2">UDS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Undecaprenyl pyrophosphate synthase</fullName>
            <shortName evidence="2">UPP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">uppS</name>
        <name evidence="4" type="ORF">HRbin05_00399</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>geranylgeranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + tri-trans,hepta-cis-undecaprenyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:27622"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57533"/>
            <dbReference type="ChEBI" id="CHEBI:60388"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="2.5.1.89"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.89" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74359">
        <property type="protein sequence ID" value="GBC74359"/>
        <property type="gene ID" value="HRbin05_00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="44"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="89"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="266" mass="31481" checksum="220932B9EB85289D" modified="2018-02-28" version="1">MRILISVIRYLLNLAGAYKVYEWYLEKQLDPKRIPNHIGIIMDGNRRWSESFMLDKFDGYAIGADKVYKAVEWCMDLGIRQITLYVLSTENLRRSKEDLESLFKVLESRLDNLYHDPRVYEKRMRIKAIGKVERLPESIKAKIHRLEEATREHDGYYITLAIAYGGRAEIVESIKRIAEKAKRGEIEPDAIDEKVIEDHLFTRELPKQEPDLIIRTSGEVRLSGFLLWQSAYSELVFLDVLWPEFRRIDLLRAIRIYQSRKRRYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCE0</accession>
    <name>A0A2H5VCE0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">flpA</name>
        <name evidence="5" type="ORF">HRbin05_00276</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the methyltransferase superfamily. Fibrillarin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74241">
        <property type="protein sequence ID" value="GBC74241"/>
        <property type="gene ID" value="HRbin05_00276"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00351">
        <property type="entry name" value="RNA_methyltransf_FlpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000692">
        <property type="entry name" value="Fibrillarin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01269">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006540">
        <property type="entry name" value="Nop17p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00052">
        <property type="entry name" value="FIBRILLARIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01206">
        <property type="entry name" value="Fibrillarin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="85"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="103"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="129"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="149"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="228" mass="25535" checksum="648A23CF31B592E6" modified="2018-02-28" version="1">MLEVEGAEEKGIKVVEVGGEERLCTRNLARGVQVYGEQLINIDGVEYRVWDPFRSKLAAAIIKGLKHLPISVSSKVLYLGASTGTTVSHVSDIAYKGIVYAVESAPRVARELIERVAKHRRNVIPIVEDARRYEHYPAMAGKVDVIYCDIAQQDQTDIAIANAKAYLKDKGYLMLIVKTRSIDVTKEPKSIVEEEVEKLRSNGFSIEKVIYLEPFDKDHAMVIARYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCE3</accession>
    <name>A0A2H5VCE3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00403</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74363">
        <property type="protein sequence ID" value="GBC74363"/>
        <property type="gene ID" value="HRbin05_00403"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="193" mass="19944" checksum="AEDD93646832FCA0" modified="2018-02-28" version="1">MNVLTACSGVSYVGMPFSLSILFASCWNMKDVRTGLLLLPYLLLSLLLLLLLLLLVLSLHTSTTVLAISTESIMVGVYTTRIPSTLLSFKHSSNALLYLDASASPIRSIGLPLLQCFGSTLLSSSMVLGSNSANLPPLAMSASVAIIAGPPAFVIIASLGPLGNGCFANASAQLNSSDISSTLITPALLNAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCF2</accession>
    <name>A0A2H5VCF2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00413</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74373">
        <property type="protein sequence ID" value="GBC74373"/>
        <property type="gene ID" value="HRbin05_00413"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004378">
        <property type="entry name" value="F420H2_quin_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04075">
        <property type="entry name" value="F420H2_quin_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="115" mass="13280" checksum="1DF25E63D7194419" modified="2018-02-28" version="1">MNGDDEGGRESFIAYLITKGRRSGKEHRVPLRLVRYNGKLYASRRDMNSDWMKNILHDQHVIVEMVDGNRLEGIARLVDDESLCRIVSMLKYKDDARASMNRVVIEIEVKGNSKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCF4</accession>
    <name>A0A2H5VCF4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">tatC</name>
        <name evidence="6" type="ORF">HRbin05_00407</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Forms a complex with TatA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74367">
        <property type="protein sequence ID" value="GBC74367"/>
        <property type="gene ID" value="HRbin05_00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="283" mass="31720" checksum="EF6D0E293540E344" modified="2018-02-28" version="1">MVVLKVVLKIRIKLFMIDKLKLVEEKTLREHLDELRIRIVRIVLAIIILSAVNLTISIRWMDLDGIPFPVPYPYPDILNSVSAQVIQAMSKELVPEHVELVQLAPGQAFFAQLQVAIILASILAMPIIVREVAGFIGPALYEDEVMAVKRITLPAVALFASGCIFSYLVIIPFMLDFLYRYGETLGIHTFLSIGEFINFVMQFIVAFGISFLLPIAMWVASSADLVDRQFWRRNIRYAIVVIAIFGALITPDGSGITMWFVALPLIALYAVGMVAVEFKIKGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCF6</accession>
    <name>A0A2H5VCF6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Prok-JAB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HRbin05_00416</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74376">
        <property type="protein sequence ID" value="GBC74376"/>
        <property type="gene ID" value="HRbin05_00416"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028090">
        <property type="entry name" value="JAB_dom_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14464">
        <property type="entry name" value="Prok-JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Prok-JAB" evidence="6">
        <location>
            <begin position="11"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="129" mass="14615" checksum="4570F0FA9F186189" modified="2018-02-28" version="1">MVRKRKVIIKKSALDSIISYCKMRHPNEAILLLCGKSSKDTATVERLMIPPFSYFGPYYSGFPTLLLPFDRSILGIMHSHPNGSSEPSLTDLNSDFIGYISMIVSYPYEDDDIHIYDSRGEKLEFSVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCG0</accession>
    <name>A0A2H5VCG0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00423</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74383">
        <property type="protein sequence ID" value="GBC74383"/>
        <property type="gene ID" value="HRbin05_00423"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="174" mass="18755" checksum="96C0859B34028D38" modified="2018-02-28" version="1">MSSRVRCHICDGIAIDHCSICKRPVCSICMGDDGVCKRCALIYDVDDDDEHDIAMMRDGRSSSSDSKDVFRIGYTALRDVVDIPMLIVGISIIIVGMLLISYASMSVSQMQGQGEGLNGATDAGRGGGGIVVIFPFPFVVLVPDAGILALVLLLVILVPFVLFFLLMRRGLRIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCG4</accession>
    <name>A0A2H5VCG4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00417</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74377">
        <property type="protein sequence ID" value="GBC74377"/>
        <property type="gene ID" value="HRbin05_00417"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="220" mass="25288" checksum="EC42F8F2FF0179E8" modified="2018-02-28" version="1">MDVERFTEDIEQVAAKLSSNEEQIVMRRINYVKQRLVELYKRNLVKINHSVLELICAKHFIKYGYDVDVERQLNDVLICDVYASKGDNVFIVEIETGFVPPEHALDPVTYTAARVASKIARYSAFAGKFALATPVLSLLPVQELFLKPPRYRNKEEVARVKALCDRYYSNPPISMEEIKNSRLHSIMIINADDARVIEIEPETYVESIKASIDRVGIKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCG6</accession>
    <name>A0A2H5VCG6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Asparagine synthetase B [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="2">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">asnB</name>
        <name evidence="2" type="ORF">HRbin05_00425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74385">
        <property type="protein sequence ID" value="GBC74385"/>
        <property type="gene ID" value="HRbin05_00425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparagine synthetase" evidence="1">
        <location>
            <begin position="40"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Asparagine synthetase" evidence="1">
        <location>
            <begin position="193"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="342" mass="38501" checksum="31B5F26BB28710E7" modified="2018-02-28" version="1">MYPAGSNDTYHTICSRLMEILKSSIYKHVSSTSIPSASKAVLLSGGLDSSIIAVLASSIDKAKDVIAICVGHEGSQDIKYARMVAERLSMRLLIKYIGMDEMLSTAREVIRVMHSFDPMEVRNSIVLYAAMKELREYGLRHVITGDGCDEIFAGYSYMLSMSYEQLEHELARLERIMHFSSIAIAEDLGMSVSLPYLDVLDYAKSIPVGLKVNEYEGKRYGKFILRLCFEHLLGKDIAWRVKMPMEQGANTSILSSYLASMVGDEYLARKSKDYLDGDRVRIRSKEHLYYYEIYRAMFGAPYLMDCGSSRDRARCSECSACISNDARFCRVCGAFPITPIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCG9</accession>
    <name>A0A2H5VCG9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Argininosuccinate lyase</fullName>
            <shortName evidence="1">ASAL</shortName>
            <ecNumber evidence="1">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 5" type="primary">argH</name>
        <name evidence="5" type="ORF">HRbin05_00414</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74374">
        <property type="protein sequence ID" value="GBC74374"/>
        <property type="gene ID" value="HRbin05_00414"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="3">
        <location>
            <begin position="35"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="4">
        <location>
            <begin position="378"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="455"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="513" mass="57490" checksum="E354C5E1B38FE1F8" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCH1</accession>
    <name>A0A2H5VCH1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="4 9">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">purD</name>
        <name evidence="12" type="ORF">HRbin05_00432</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GARS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="4 9"/>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74392">
        <property type="protein sequence ID" value="GBC74392"/>
        <property type="gene ID" value="HRbin05_00432"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="11">
        <location>
            <begin position="116"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GBC74392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="442" mass="48986" checksum="D1BF726ABDB45A72" modified="2018-02-28" version="1">MLYHCGGVKMNVLVLGSGAREHAIGWKVANSSKVEKVFFAPGNGGTRLAGYENLGIGIKEHDRLLRFAMEHECLTIVGPEEPLAMGIVDLFKGNGLRILGPSRDAARLESSKVWAKEFMKRHGIPTAEFKVFDEPEAAKDYIARSKRDDVVVKADGLAAGKGVVVCSSKAEAYNAVDMIMKDRVFGDAGNRIVLEERLYGEEVSFICMSDGKRIIPLATSQDHKRVYDNDEGPNTGGMGAYSPNPIIDGKIHEWIMRNIMQKAIDGLRHDGVEFKGFLYAGLMLVGDKAYVLEFNVRLGDPETQVILPRLRSDLIYYVEHCIDGTLDQAEDMVWDERVAVCVVLASKGYPNAYEKGKVITGLDDLNSMYSNGDHLVFHAGTKVTDDGRIVTDGGRVLSIVALGSDMKEAIEKVYSAVNRVHWEGMHYRRDIGKRALRYLLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCI0</accession>
    <name>A0A2H5VCI0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00442</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74402">
        <property type="protein sequence ID" value="GBC74402"/>
        <property type="gene ID" value="HRbin05_00442"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="31" mass="3562" checksum="4AA7ABC6ECD21341" modified="2018-02-28" version="1">MHMLMMIVIEKGVITVLMPIRLLIPKVRLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCI1</accession>
    <name>A0A2H5VCI1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00438</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74398">
        <property type="protein sequence ID" value="GBC74398"/>
        <property type="gene ID" value="HRbin05_00438"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="155" mass="18224" checksum="6F29F09D48854663" modified="2018-02-28" version="1">MRWGIEQEEYYFKIYDEDKNVAAYFQPDYGQIEPKEREYEIIERMLKHGDPITSGLLYMPMAKFNIRDDADYSIDDVISSIEDALSRIKQWRGVVGMRGSGYVIEHAWVRRAHTDYDMLAILLVVRFNIQVRLFKKEILNALAELLDLLVDNGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCI2</accession>
    <name>A0A2H5VCI2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00424</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74384">
        <property type="protein sequence ID" value="GBC74384"/>
        <property type="gene ID" value="HRbin05_00424"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="33"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="136" mass="15369" checksum="9F74CE2CA076BBA2" modified="2018-02-28" version="1">MLLPSEIESRSLIPAIRAIISRRLVNEYNMKEEDVAKLLGITQAAVSNYIRGTRGDAELAKRLMSEPTVVRRIDEISNELATNRAFMPSTMAKYIGLLNYIRHSLLICDIHHAIEKSIDKDICKACEDTLREGLRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCI3</accession>
    <name>A0A2H5VCI3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH 2</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH2</name>
        <name evidence="5" type="ORF">HRbin05_00437</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74397">
        <property type="protein sequence ID" value="GBC74397"/>
        <property type="gene ID" value="HRbin05_00437"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007330">
        <property type="entry name" value="MIT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036181">
        <property type="entry name" value="MIT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015415">
        <property type="entry name" value="Vps4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09336">
        <property type="entry name" value="Vps4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00745">
        <property type="entry name" value="MIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116846">
        <property type="entry name" value="SSF116846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MIT" evidence="4">
        <location>
            <begin position="5"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="178"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="80"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="422" mass="47127" checksum="0CA931B86B82E0A5" modified="2018-02-28" version="1">MTLAPQELENIASKHAAEAIKLDSQGAKPHAILHYQKAVDALLKLVHLYPDYKLNKIYVERAKAYQNRIKALQESRGLDGMHDMVNGDKGSSKGSEQANTAISKVRHDSVGGERSNGNGLSSNDTNVEILKADFDDLVLKDKPNVKWDEVIGLDDAKRALRESIIYPTQRPDLFPLGWPKGILLYGPPGNGKTLLAAATASEIEGYFINVDAASMMSKWLGEAEKNVAKLFSMARRVVSKENVPVILFIDEVDSLLGTRSNEIGGEVRVKNQFLTEMDGITSKSGRSPIYVIGATNKPWSLDWPFLRRFQKRIYVGLPDYNARLQMFRSYTAQLNIDPSLKLEDLAKITEGYSASDIRDICQGVQLKVVNELFESGKAFDGNAQTRSIGMNDFKEILKNRKPSVSQEMIKAYLRWTEQFKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCK0</accession>
    <name>A0A2H5VCK0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-oxoglutaramate amidase</fullName>
            <ecNumber evidence="3">3.5.1.111</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00444</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.111" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74404">
        <property type="protein sequence ID" value="GBC74404"/>
        <property type="gene ID" value="HRbin05_00444"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106008">
        <property type="term" value="F:2-oxoglutaramate amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="2"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="287" mass="31660" checksum="DD5A7CA222A86CD4" modified="2018-02-28" version="1">MTRVALLQLELKDSPDDAMEHAVKLLQQVGAANSEIVCLPEQWYPKHLESIDELKPIQDVAREHNMVVIAGAFFEYIDEDDGEGMHIHGDESAGSSSSSGGSSSNSNSNSNTAARSIYISAPVIGADGSIVGRQFKLHPFGRELSMVKPGRRIRIFEHNGVRFGIGICHDVVFPEVARLAARNGADILFFPSKIVNEGIEPWQIYVKARALENRTPVVAPNLCSKEYGGMSIIVDLVRNESLDIVLPYVVVASAGEHVLISDIDVELSRTLRKARMMELRDDDYYII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCL2</accession>
    <name>A0A2H5VCL2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HRbin05_00476</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74436">
        <property type="protein sequence ID" value="GBC74436"/>
        <property type="gene ID" value="HRbin05_00476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006418">
        <property type="term" value="P:tRNA aminoacylation for protein translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="127" mass="14969" checksum="E7DCBC8952327E1A" modified="2018-02-28" version="1">MDVKVSSKMSKSKPHTSIFIHDDEHIIREKMRRAWCPESIDSNPVLEIVRYIIFHEFKEFTVERPAKYGGSITFASYKELEEAYASRRLHALDLKNAVALYLNKIVEPVREYLKNRKEIMEVLAKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCM3</accession>
    <name>A0A2H5VCM3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA mutase</fullName>
            <ecNumber evidence="3">5.4.99.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">scpA</name>
        <name evidence="3" type="ORF">HRbin05_00450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.2" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74410">
        <property type="protein sequence ID" value="GBC74410"/>
        <property type="gene ID" value="HRbin05_00450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="2">
        <location>
            <begin position="34"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="555" mass="63101" checksum="3579A84379AF97CB" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCN4</accession>
    <name>A0A2H5VCN4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00487</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74447">
        <property type="protein sequence ID" value="GBC74447"/>
        <property type="gene ID" value="HRbin05_00487"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="61" mass="7292" checksum="D89F9D763FCE55E1" modified="2018-02-28" version="1">MTKRWKNKVQYGYSWIAESVFSSLKRLFDGEHVIAKKYMNMVKEMILKVSLYNLFLNITAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCN7</accession>
    <name>A0A2H5VCN7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">D-tyrosyl-tRNA(Tyr) deacylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HRbin05_00504</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74463">
        <property type="protein sequence ID" value="GBC74463"/>
        <property type="gene ID" value="HRbin05_00504"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018033">
        <property type="entry name" value="Deacylase_DtdA_archaea"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007508">
        <property type="entry name" value="DtdA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34667">
        <property type="entry name" value="PTHR34667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04414">
        <property type="entry name" value="tRNA_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016210">
        <property type="entry name" value="UCP016210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="293" mass="32777" checksum="7D8400406850E964" modified="2018-02-28" version="1">MYPLLIASRDDICAMNMASYLITQCSMEVYNDGSNSSSRKIYSCPYFTLMLIDGSVLEAEWIDQWLSSNSSGSKKHDSNDTNTTMVIDVDCYIFLSRHRSKSNKPTLTCHSTGNFSHAVMGGNARELAYTYPSLQKCYMLNLYSNRGKVPNYDIVIEATHHGPTSLAKPVLFIEIGSSEREWSDMDAISVTCESLLSSIVNFKEYGRKVGIALGGTHYPEKFTNLLIDSDIALASVASKHNLKHVDELMLRQMIAKSIEPVRYIILDWKGLGSEKDRIVNLANSVEGMEVIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCP2</accession>
    <name>A0A2H5VCP2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA protection during starvation protein 2</fullName>
            <ecNumber evidence="4">1.16.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dps2</name>
        <name evidence="4" type="ORF">HRbin05_00499</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Dps family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.-.-" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74458">
        <property type="protein sequence ID" value="GBC74458"/>
        <property type="gene ID" value="HRbin05_00499"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016722">
        <property type="term" value="F:oxidoreductase activity, acting on metal ions"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01043">
        <property type="entry name" value="DPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002177">
        <property type="entry name" value="DPS_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023188">
        <property type="entry name" value="DPS_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42932">
        <property type="entry name" value="PTHR42932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005900">
        <property type="entry name" value="Dps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01346">
        <property type="entry name" value="HELNAPAPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00819">
        <property type="entry name" value="DPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="3">
        <location>
            <begin position="24"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="165" mass="19106" checksum="E513EB81D632ECD7" modified="2018-02-28" version="1">MEVTVTTTPKIDIGVSKESREGTIKILTVLLADEYTLYTKTKNYHWNVTGTNFNELHEFFGKQYEELDEIIDEVAERIRQLGGYATGTLAEFLSMARIKEEPGKYPDARSMLSNLLSDHEYIIRTIRKDADTVADNYHDMGTNDFLIGIMQRHEKMAWMLRAYLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCP3</accession>
    <name>A0A2H5VCP3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Regulatory protein AsnC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">asnC_2</name>
        <name evidence="5" type="ORF">HRbin05_00498</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74457">
        <property type="protein sequence ID" value="GBC74457"/>
        <property type="gene ID" value="HRbin05_00498"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="163" mass="18499" checksum="5261CE9C5828CC5A" modified="2018-02-28" version="1">MNRLDELDLKILYELVNDASISVPEMSRKIGANTSVIYSRIKRLLKLGVIKKYTIIMDESKLGVNINAIVGINRDPKAKQHVYEEIKNIPQVTNISEVSGRFDMLVSIGVKNLEELHNVVINRIGKIDGILNTETFVELHKSENKAVYVKSLLEQQKQKVVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCP5</accession>
    <name>A0A2H5VCP5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00506</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74465">
        <property type="protein sequence ID" value="GBC74465"/>
        <property type="gene ID" value="HRbin05_00506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="66" mass="7210" checksum="FC15B697B4FBCBEB" modified="2018-02-28" version="1">MKSRIDKEFLFGNNLTVGGVGLKDGSGVGATILVVDSYYEDAVKAKLDDIRAVLMVELIARLFYLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCR5</accession>
    <name>A0A2H5VCR5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Homoserine dehydrogenase</fullName>
            <shortName evidence="7">HDH</shortName>
            <ecNumber evidence="3 7">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">hom</name>
        <name evidence="12" type="ORF">HRbin05_00526</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="3 7"/>
    <dbReference type="EMBL" id="BEHH01000022">
        <property type="protein sequence ID" value="GBC74485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74485">
        <property type="protein sequence ID" value="GBC74485"/>
        <property type="gene ID" value="HRbin05_00526"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022697">
        <property type="entry name" value="HDH_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036497">
        <property type="entry name" value="HDH_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 7 9" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7 12" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="NAD_binding_3" evidence="11">
        <location>
            <begin position="16"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Homoserine_dh" evidence="10">
        <location>
            <begin position="181"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR036497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GBC74485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="369" mass="40264" checksum="C8AB4984F60848EF" modified="2018-02-28" version="1">MVEEEGWVRLRIILVGFGVVGQNLVKLLLSRADDIYLRYGMKPRLVATVDSKGVAVSQSGLDLQRLLEVKRLYGTVAAYHDDGQRGESADIDLIDRKKGGRCRVEEIIREMDAEVLVEATPTNLNDGEPGLSNITTAIKHGRNVVTVNKGPLALAMPSLLELAEYNGVMLRFSGTVGGGTPILEFAKHCLRGDRILSFKGILNGTTNYILSMMEDGLTFDEALNDARSKGYAEADPSLDIDGFDAAAKLVIMANWIMGMKVTMRDVRFKGIRDVRLEDILEAKKHGKVIKLIASCDESRRLRVEPMSIDKNEPLCVNGTLNAVTFTSEHSGELTVIGKGAGGMETASAILRDLIEVREAMGMGIGLNRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCR9</accession>
    <name>A0A2H5VCR9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00533</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000022">
        <property type="protein sequence ID" value="GBC74492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74492">
        <property type="protein sequence ID" value="GBC74492"/>
        <property type="gene ID" value="HRbin05_00533"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="100" mass="11414" checksum="436B45032E9D319A" modified="2018-02-28" version="1">MKVEGPDKDGMCWPKCTWFKCGKNVLRFKGNILWCDWLEQECLGPSCAYASCVRSKLLTEGRCGLVIRRRTRDSLSPDDFRLDVKLKGKLAKMVKGDDVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCT1</accession>
    <name>A0A2H5VCT1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">tRNA pseudouridine synthase D</fullName>
            <ecNumber evidence="6">5.4.99.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">truD</name>
        <name evidence="6" type="ORF">HRbin05_00411</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the pseudouridine synthase TruD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.27" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74371">
        <property type="protein sequence ID" value="GBC74371"/>
        <property type="gene ID" value="HRbin05_00411"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001656">
        <property type="entry name" value="PsdUridine_synth_TruD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020119">
        <property type="entry name" value="PsdUridine_synth_TruD_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011760">
        <property type="entry name" value="PsdUridine_synth_TruD_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042214">
        <property type="entry name" value="TruD_catalytic"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13326">
        <property type="entry name" value="PTHR13326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01142">
        <property type="entry name" value="TruD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037016">
        <property type="entry name" value="Pseudouridin_synth_euk_prd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50984">
        <property type="entry name" value="TRUD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01268">
        <property type="entry name" value="UPF0024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TRUD" evidence="5">
        <location>
            <begin position="213"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="471" mass="53900" checksum="8A861CABA1A0FCC5" modified="2018-02-28" version="1">MHIVSDLDRMIGLEVYSTATEGVKGRIRRSSNNSRSDGHYDHFMVEEVIDVDGRISISKVRDNRHRYPLFILRKEGIDTIHALKELESKYGLRLNALGLKDANASTLQYVTSDRVLEVRRRKREKIGSEKGDGDGEGVEGGRGMGMKEVDEEEEEKELSTRHCSIKFVGYLDRMLRKRDLIGNRFTITIEIDPSDHEYLEKIKSVIMEVRARRVGNFYGYQRFGSIRPVTHLVGKAITKRRFREAVDTFLTYIGEYEDERSRNVRLMLRDGLSEESIEHIPYHMDLERDLVESMIKSSDPLRALRRLPISVRRLFVEAYQAYIFNRTLSIAIREGYDISTPSMGDICFSVDVNNKVGDICRFDGSRSKDGLVPAIPLVGFAFKPIGRFGTIVERVMEEEEICSKDFYIKEMQEVSVEGGFRPSPLLLLYNTFEILSSNGGIRVRFALPKGSYATVLLREVIKPAQPTLVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCT3</accession>
    <name>A0A2H5VCT3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74498">
        <property type="protein sequence ID" value="GBC74498"/>
        <property type="gene ID" value="HRbin05_00539"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRAM" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="45" mass="4884" checksum="84615A85A91E5A0B" modified="2018-02-28" version="1">MSKKGDGVARIKGFVIFVQGAEIGKEYKIRISNVANRFATAEIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCT7</accession>
    <name>A0A2H5VCT7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00558</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000025">
        <property type="protein sequence ID" value="GBC74516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74516">
        <property type="protein sequence ID" value="GBC74516"/>
        <property type="gene ID" value="HRbin05_00558"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="6"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="67" mass="8125" checksum="F4B0638E17C405B2" modified="2018-02-28" version="1">MSTLYEESIRRLLDEKRRRLEEIVREGNSPYEIARLEHEIHVLEMLYENYSSSMSAFRRTKGARKLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCU7</accession>
    <name>A0A2H5VCU7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Iron-sulfur cluster carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">apbC</name>
        <name evidence="1" type="ORF">HRbin05_00557</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000024">
        <property type="protein sequence ID" value="GBC74515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74515">
        <property type="protein sequence ID" value="GBC74515"/>
        <property type="gene ID" value="HRbin05_00557"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="216" mass="23587" checksum="15B3D87258C44AD2" modified="2018-02-28" version="1">MLGLSPGLMVNSENRIVPQEVHGIKVMSMGLVTTRGEENVGIWRGPIISGIIKQFLTDVEWGELDYLIVDLPPGTGDAPLTLAQTIPITGVVIVTTPQDVAMNIARKSALMFRKLNIPIIGVVENMSYFICPHCSKESRVFGYSSEEKIEERFGAPLLGEIPLHTSIMEGSETGKPIMLLEPESPYARAVEMIARRVAGRVSIIAAEMQDASVIQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCV8</accession>
    <name>A0A2H5VCV8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00571</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74529">
        <property type="protein sequence ID" value="GBC74529"/>
        <property type="gene ID" value="HRbin05_00571"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006833">
        <property type="entry name" value="NH3_CH4_mOase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023301">
        <property type="entry name" value="NH3_CH4_mOase_suB_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04744">
        <property type="entry name" value="Monooxygenase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="209" mass="22801" checksum="86184A5320F1DAD6" modified="2018-02-28" version="1">MKVMHVAVLTAVAVVLVLGSFAPIMKDAFAHGVQAQLQSRFIKIEDETFSTFRVITKQEYANRTGLTLEQIDAMGCDPRRQDILIVTGRLVSQVNKDLRAWISLFNESTNAGNRWEFILREPPGNVFDIPPGGEVPYKLCVAALEPGTYHTHTQLNVASVGPGLGPGATVVVEGEPTMKPMSVGNVIYQTILIAIGLAISFATRPWQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCV9</accession>
    <name>A0A2H5VCV9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74533">
        <property type="protein sequence ID" value="GBC74533"/>
        <property type="gene ID" value="HRbin05_00575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="66" mass="7026" checksum="DEA1A21D5FF0A1E3" modified="2018-02-28" version="1">MMMKNYSMLAVLAIVAVAAIAAVTPSAYAQTWGRPDSMIIAGLPLIVGLGTGIVYFIVISARRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCW2</accession>
    <name>A0A2H5VCW2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00569</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74527">
        <property type="protein sequence ID" value="GBC74527"/>
        <property type="gene ID" value="HRbin05_00569"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="85" mass="9919" checksum="8F0698454E3AA498" modified="2018-02-28" version="1">MDIATLAMGIKNIVLQIGPAYDPLFYDVMIYIFGTMMFGIFLLSVIAYWIRHKGIGGTARETWVQELERYYEREGIGLLPEERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCW6</accession>
    <name>A0A2H5VCW6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AsnC_trans_reg domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00588</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74546">
        <property type="protein sequence ID" value="GBC74546"/>
        <property type="gene ID" value="HRbin05_00588"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="6"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="80" mass="9010" checksum="A51286E0D0F804A0" modified="2018-02-28" version="1">MPSAYVLINCDLGSEEEIIREIKSIRGVKEVKGTYGVYDIVVKVDGNSMEELKDTITWKIRRLPKVRSTVTLIVIEGQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCX0</accession>
    <name>A0A2H5VCX0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00579</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74537">
        <property type="protein sequence ID" value="GBC74537"/>
        <property type="gene ID" value="HRbin05_00579"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="273" mass="31687" checksum="6E2A4428DE759F6B" modified="2018-02-28" version="1">MNRFKHLYIYMLTSKVDSNSILAYLTSMINCNIESRGADALYRGLDEHSIAEMYASCRVKDIFKDINSNYTTHVSEDVEYELSILNGAPSQPNVVYDGFRLQYIYSSMIDADESSLDNVHVVVTDRLLATYSEEDMRYHLNTVVLGYPSIVSIDGIVEAPAKPRAFYTLYYYHISRGIEISMDEVKSIFKDVMLEHDDPRLTDVAKGYIMQALFYSMLNDAPFCDDKRCILYNAHWQDEVIEAQIRYGRLCTKHREVLDEFNKHHDRNYDATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCX6</accession>
    <name>A0A2H5VCX6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Manganese-dependent inorganic pyrophosphatase</fullName>
            <ecNumber evidence="3">3.6.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ppaC</name>
        <name evidence="3" type="ORF">HRbin05_00598</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74556">
        <property type="protein sequence ID" value="GBC74556"/>
        <property type="gene ID" value="HRbin05_00598"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="2">
        <location>
            <begin position="9"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="387" mass="42011" checksum="ABB0E3C377F2A4FE" modified="2018-02-28" version="1">MMKRRIRHLCIITHRLADVDAYCSAYALSSLFKKYARDITVVFPAGLNAIASKVMQHLPLDVRTVIIDEGKDGDNDNDGKGSNNGSSGGINSNNNNNKDGNNNKCVNNSLTRDVASVVGMLENYDENDLILIVDTNNPVMLAGVSEGVARSKARKVLIDHHPIAVEASVLGIDEMRVDVDASSTCEMVYRLFKELRRRLSRDVAMALLLGVLTDTQNLTIAKCSTVPMLADICRFTSLEECRSILAVERDYSERIARLKAAQRCRLYRVKVGNTADSNSNPSIIIIAVSKVGSHHASAAKALVDLGADLSIVVSREGSIAKASLRSTQSFYTRTKLHLGTDILARISSAGGGHSTAASIALEMDEDGLIRSILQVIKERLGRLDALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCX7</accession>
    <name>A0A2H5VCX7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00591</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74549">
        <property type="protein sequence ID" value="GBC74549"/>
        <property type="gene ID" value="HRbin05_00591"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="265" mass="29485" checksum="E56A564673575A48" modified="2018-02-28" version="1">MLDEHIRCRVMSGEGKEEAEVKEELHASISKPPVNLLFNPSLASRKGIWSISISYLLERFLSILEQMRSKDLRLCGVAALSSAIIFRLKVESIFMLERIANQHRQVAKEGNSSSSNSMVDLSSISLEMPYRHEVAYDLTLEDLLEMLSSIVERIYLSSKQGAVDTTSTDLSIEPVGSSLTGIDDYLITLERLIDDYKSRLYALVMEQGSISFNGLTLGLEPIEVARYFIALLHLCIDGKVDVLEAADDDILISIRSTSSSCTTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCX9</accession>
    <name>A0A2H5VCX9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoglycolate phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.18</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gph</name>
        <name evidence="2" type="ORF">HRbin05_00562</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.18" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000025">
        <property type="protein sequence ID" value="GBC74520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74520">
        <property type="protein sequence ID" value="GBC74520"/>
        <property type="gene ID" value="HRbin05_00562"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008967">
        <property type="term" value="F:phosphoglycolate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="221" mass="25417" checksum="64B017F06E16C71E" modified="2018-02-28" version="1">MDMLIVFDFDGTIANTVHTLIRIINKLADEFAYKKIRMYDLHHVKGMRTRDILVYLNIPMLKLPFIIRRIRMEMNKEIPMLKPSVNIKPTLEALKNEGCKLGILTTNATSNVRAFLKSNDLELFDFIRSTHHLLAKHVILKKIKKSYCYHCNSNPNPSMIFYVGDEVRDIEAGKRAGAKTVAVSWGFNSRGALLAEMPDYIIDRPEELEYIAKKALTIGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCY3</accession>
    <name>A0A2H5VCY3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74548">
        <property type="protein sequence ID" value="GBC74548"/>
        <property type="gene ID" value="HRbin05_00590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="149" mass="16156" checksum="917228B1923F0468" modified="2018-02-28" version="1">MRYTFMVLVAIAVVGVLGIPLGDPRFIYTAITLECAYIALAVLALRIGNGVDVWSRVGTMVKESRSSSKSKSKRSRSSSMIVTVPSIAIASMVIVANTLSTTHLSIMMSLTPLYNALILIVGGYVLQVLLIISSIYEYSRVRLADLNAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCZ4</accession>
    <name>A0A2H5VCZ4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74558">
        <property type="protein sequence ID" value="GBC74558"/>
        <property type="gene ID" value="HRbin05_00600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="97" mass="10777" checksum="0507E135C8616DFD" modified="2018-02-28" version="1">MISRVDATVEVEDDRSSGRDRESSSISVVRSIYVALEPECRANSKGKDEGVETSIVLEDSRVRVMIHAKDVSTIRAVLNSYLRFIDAAYRSLAATKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD06</accession>
    <name>A0A2H5VD06_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74575">
        <property type="protein sequence ID" value="GBC74575"/>
        <property type="gene ID" value="HRbin05_00617"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="42" mass="4937" checksum="51A8CD348A196A95" modified="2018-02-28" version="1">MMDLQMLALWSIITITFMVVTGFVYSRVMKGKVDEHEHVYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD20</accession>
    <name>A0A2H5VD20_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH_45 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00631</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000031">
        <property type="protein sequence ID" value="GBC74587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74587">
        <property type="protein sequence ID" value="GBC74587"/>
        <property type="gene ID" value="HRbin05_00631"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038723">
        <property type="entry name" value="ArnR1-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14947">
        <property type="entry name" value="HTH_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_45" evidence="1">
        <location>
            <begin position="19"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="127" mass="14983" checksum="B19E8F22A360D42A" modified="2018-02-28" version="1">MINDYTNTSIRMKRKRRGKRGPLMIIISILDVLDGSDTNKTNLSYKTNLDIRILNKYLEFLGERGLVRYNDNNNNDDSYVSRGVYDPTLIRITDKGREVLFHFKEAIRLMDDECDLRDRCALRRYAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD21</accession>
    <name>A0A2H5VD21_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rad51 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00492</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74451">
        <property type="protein sequence ID" value="GBC74451"/>
        <property type="gene ID" value="HRbin05_00492"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="DNA_recomb/repair_Rad51_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rad51" evidence="2">
        <location>
            <begin position="3"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="55" mass="6252" checksum="CBC0414E9715986E" modified="2018-02-28" version="1">MYLKRSGRHRIARMVDSPYHPEREVTFVLSEKGVEDVEEKEKKGKGSSNSNSSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD26</accession>
    <name>A0A2H5VD26_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000032">
        <property type="protein sequence ID" value="GBC74596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74596">
        <property type="protein sequence ID" value="GBC74596"/>
        <property type="gene ID" value="HRbin05_00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="94" mass="10442" checksum="B19616A9437168D1" modified="2018-02-28" version="1">MPSSPPSLSSSLLLLLISAGVASGIASALYLYFNREPLMVQLTIHALMFPSGYILLYLYKRVRNYKSIAVYLVSALPLHLLIHILLIRDITITP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD44</accession>
    <name>A0A2H5VD44_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HRbin05_00653</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74609">
        <property type="protein sequence ID" value="GBC74609"/>
        <property type="gene ID" value="HRbin05_00653"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="123" mass="13644" checksum="7CA556AFFF5352EF" modified="2018-02-28" version="1">MMEEVSHMIRESSIMKIHYYTGLAAIVLVAIHILFRLTVPEGYSASLEYENVIANYKNISYSLVLELILVTVAIHGFNGLRVILLELRQGDGWESAVKWLCIAGAVAVIAYGTRTILLASMMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD80</accession>
    <name>A0A2H5VD80_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00698</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74653">
        <property type="protein sequence ID" value="GBC74653"/>
        <property type="gene ID" value="HRbin05_00698"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="29" mass="3597" checksum="9C70627166419039" modified="2018-02-28" version="1">MRRRVRGGGRKKNDMHAKHYYISQHKISW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD81</accession>
    <name>A0A2H5VD81_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hisS</name>
        <name evidence="3" type="ORF">HRbin05_00674</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000035">
        <property type="protein sequence ID" value="GBC74630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74630">
        <property type="protein sequence ID" value="GBC74630"/>
        <property type="gene ID" value="HRbin05_00674"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="2">
        <location>
            <begin position="51"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="423" mass="47598" checksum="CC41AE7A7DBA14EF" modified="2018-02-28" version="1">MRDIEDEEYMLIEHARDRFIESARLFNFSMVEPSPIELLSTLEAKSGPMIADEIYAFKDKAGRDIALRFDLTVGITRYVAGRRDLKMPIKLAAFGPVWRYDEPQMGRYRWFHQWDVEIYDNFSIESDAEVIEFTKHYLNSLGIQARIEVSDRRMLEGMIRRRLGIEDEHQVLEMLRAVDKLSKKSRDAILQEYASKGIDAERLRLLLDVAGLKGSLDDVLKSDHLKGMDVDTSRLTALIDSLKARGVSDVVVNMGIVRGLDYYSSIVFEVFSGKSNLALVGGGRYDILPEVFGRKDMGATGAAGGVERLILLLKDIHGEGDGLIMHRKNMASIFIAYADDGLRSKAVMLASDLRRKGVKSECIAASLKRQLDYASSKGYRFAAILTDRLGKEKMVTLRNMVDGSEKVIMLDKLLTDPLAVIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD93</accession>
    <name>A0A2H5VD93_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00711</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000040">
        <property type="protein sequence ID" value="GBC74666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74666">
        <property type="protein sequence ID" value="GBC74666"/>
        <property type="gene ID" value="HRbin05_00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="198"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="322" mass="34795" checksum="1323B33FCAFD62E5" modified="2018-02-28" version="1">MPIVEYISKLIVRRAVWLVLCSLVLGIFFSNISLAYLLPLIPVFLAGMMGSAGLMITMRDLFRSGIKVSKISIILASQFILSTSVGFILALIFFNVISDLPNLALGQVLHGAMPSEQTTPVWIRLTGGNTALGIATLILSTIASPFVSPVMVLLFAGRWVNLEYMLMFESLLLSVMLPVVVGSFIRSKYNAMARYDNVFSAASILFALPTVAIVGALAASFLSLQPLSIVLLAVIASLAHFVSTLLAGLAISKVLRWDALDTPVSIYNLSMKEFTVTLGVITMTGLEPEVGVPASIYGMMHMASAPIIARWLYSTQIRKNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDA2</accession>
    <name>A0A2H5VDA2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00718</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000041">
        <property type="protein sequence ID" value="GBC74673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74673">
        <property type="protein sequence ID" value="GBC74673"/>
        <property type="gene ID" value="HRbin05_00718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="562"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="595" mass="64320" checksum="9ACEB8628F9CE644" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDA3</accession>
    <name>A0A2H5VDA3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative ABC transporter ATP-binding protein YknY</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">yknY</name>
        <name evidence="5" type="ORF">HRbin05_00717</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000041">
        <property type="protein sequence ID" value="GBC74672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74672">
        <property type="protein sequence ID" value="GBC74672"/>
        <property type="gene ID" value="HRbin05_00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="231" mass="25412" checksum="0CFFF0EC02D551ED" modified="2018-02-28" version="1">MDSGVVLRTENLSKIYNGGYVKVAALKNVNLTIRRGEFVTIIGPSGSGKSTLLNLLGALDRPTSGKVYIDGIDIYSYSDRELAIIRNRKIGFIFQAFNLINRSTVLKNIEMPAIIAGVPKDVRIAKAMQLLKMLGIEDKADFKPISLSGGQQQRVAIARALINDPAIILADEPTGNLDSKTGLEVIELLNTLCSKYNKTVIMVTHNLEHASMSTRSIYIRDGMIEKEVVYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDB2</accession>
    <name>A0A2H5VDB2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Glutamyl-tRNA(Gln) amidotransferase subunit D</fullName>
            <shortName evidence="5">Glu-ADT subunit D</shortName>
            <ecNumber evidence="5 7">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ansA</name>
        <name evidence="5" type="synonym">gatD</name>
        <name evidence="12" type="ORF">HRbin05_00729</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Heterodimer of GatD and GatE.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the asparaginase 1 family. GatD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="5 7"/>
    <dbReference type="EMBL" id="BEHH01000043">
        <property type="protein sequence ID" value="GBC74683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74683">
        <property type="protein sequence ID" value="GBC74683"/>
        <property type="gene ID" value="HRbin05_00729"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08962">
        <property type="entry name" value="GatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00586">
        <property type="entry name" value="GatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006033">
        <property type="entry name" value="AsnA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027475">
        <property type="entry name" value="Asparaginase/glutaminase_AS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011878">
        <property type="entry name" value="GatD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040918">
        <property type="entry name" value="GatD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037222">
        <property type="entry name" value="GatD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18195">
        <property type="entry name" value="GatD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500175">
        <property type="entry name" value="Glu_ADT_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141300">
        <property type="entry name" value="SSF141300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="SSF53774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00519">
        <property type="entry name" value="asnASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02153">
        <property type="entry name" value="gatD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00917">
        <property type="entry name" value="ASN_GLN_ASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GatD_N" evidence="11">
        <location>
            <begin position="16"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase" evidence="9">
        <location>
            <begin position="120"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase_C" evidence="10">
        <location>
            <begin position="336"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF18195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GBC74683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="456" mass="50664" checksum="8E63649E831C919C" modified="2018-02-28" version="1">MYKGNAYKLLESYDVKVGDRIVVKTRDNEYRGILMPRYELADDMHLVIKLRSGYNIGVSIDEIVSITLESTREEEEEEAVIVGRGEVDGEGEEEEERKRRDHRAVSLEHGYVYEHSTRIRLAMISTGGTIASRIDYRTGGVKAALTAEELYSIVPELSSIALIDAEVLMQEYSENLTPMHWSIMAERVGEKMEQGYDGVVIAHGTDTMHYTSSALSFALQNLPVPVVLVGAQRSSDRPSSDAATNLIGASLFAANADTSGVFVAMHNGRSDDKIAIHMGTRVRKNHTSSRDAFKSIDAEPIALVDVDSRRIEMLASNIRGRDKGRRPVVKAKFDERVALIKFYPGFDPSIIEYLISKGYRGLVIEGTGLGHVSKRCFNAIRDATASMLVCMTSQCIWGRLRMTVYDTGRDLLSMGVVPLDMLPETALTKVMWVLANSSSMDEARSMLLSNIAMEFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDC0</accession>
    <name>A0A2H5VDC0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diaminopimelate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">lysA</name>
        <name evidence="4" type="ORF">HRbin05_00738</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000045">
        <property type="protein sequence ID" value="GBC74692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74692">
        <property type="protein sequence ID" value="GBC74692"/>
        <property type="gene ID" value="HRbin05_00738"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="3">
        <location>
            <begin position="55"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="2">
        <location>
            <begin position="309"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="490" mass="55425" checksum="32A7FC73C1AF65AA" modified="2018-02-28" version="1">MEYTNKELGEHKSKLQLVQEINLNLNRFMSDDELYEAIEKFGTPLYIIDEETLHRKVRELLDAYKGFKGKRQIAYSVKANFNPSVIRAFIKDAIMFDLTSLGELYFYTRCGGDASAVIYTSVAEEEDEYLQVLKAGVGRVVVSSYNGLLNLISAASRLGIRPRTMIRINPEIAVKAEVKASYRHGKFGVPFNTNARDSATNMIKRIMQDNMLEFEGFHFHLGSQITDYTCFTHALDRLDAFITNMKKIYPNFTFNTIDIGGGTPVSYGEYVPTPAEMASSIVDKLNRIAENHNNNFTLVIESGRYLTAESTILVSRIVNTKEYTNDRFLIVDSGYHILLDAALLKQEYPQEVFPSKDDNSSSNSSSSSDYSNNSNGNSSNYHSKYDARSCNGNNSNHNESYTPVRTHLVGRLCDTYDIFPISKASRLNGAKKNRYIVFYNVGAYSIVFNMPFHCQTKPPILMKMSDGRLVLVRKPTTIEHLFLEEGGDML</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDC8</accession>
    <name>A0A2H5VDC8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000040">
        <property type="protein sequence ID" value="GBC74670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74670">
        <property type="protein sequence ID" value="GBC74670"/>
        <property type="gene ID" value="HRbin05_00715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="43" mass="4690" checksum="420AB8EF84D306F0" modified="2018-02-28" version="1">MLAVVVLVMVTMTIVVVGRKRMFMASPYTLDTATMGEGVSVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDE7</accession>
    <name>A0A2H5VDE7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00736</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000045">
        <property type="protein sequence ID" value="GBC74690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74690">
        <property type="protein sequence ID" value="GBC74690"/>
        <property type="gene ID" value="HRbin05_00736"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="82" mass="9622" checksum="2B42D64C84F4FED4" modified="2018-02-28" version="1">MLMDIRDYVLSLPSVIEEIRPHRIVYSKGFNMRIFMDIEPAMNMLAVNIKTESRAPPSRILLRSINQLQDLYGMIRKAYEHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDE9</accession>
    <name>A0A2H5VDE9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Poly(3-hydroxyalkanoate) polymerase subunit PhaE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HRbin05_00624</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Biopolymer metabolism; poly-(R)-3-hydroxybutanoate biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000031">
        <property type="protein sequence ID" value="GBC74581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74581">
        <property type="protein sequence ID" value="GBC74581"/>
        <property type="gene ID" value="HRbin05_00624"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00917"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042619">
        <property type="term" value="P:poly-hydroxybutyrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010123">
        <property type="entry name" value="PHA_synth_III_E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09712">
        <property type="entry name" value="PHA_synth_III_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0583">PHB biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="147"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="190" mass="21911" checksum="44E7DA6E083C2F24" modified="2018-02-28" version="1">MENGREEYMDSVEKLLDSLALIRKIPQFRAFMPIRVIEVTEEALLSYSRISASLASSIAEYYMLLSATSLEASRKAALKMAEIKDGEKARKAWIDVFEQEFNELFRSQRFGNVVNNIITSYADLLKSIAGIVEVYFKELGLPTRSEMDSVYREMVKMKRDIANLADEMKRLKEDIERRKDENIHNAVLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDF8</accession>
    <name>A0A2H5VDF8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malate dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.37</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mdh</name>
        <name evidence="2" type="ORF">HRbin05_00635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000032">
        <property type="protein sequence ID" value="GBC74591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74591">
        <property type="protein sequence ID" value="GBC74591"/>
        <property type="gene ID" value="HRbin05_00635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ldh_1_C" evidence="1">
        <location>
            <begin position="7"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="166" mass="18017" checksum="28FF24CB2443FCE2" modified="2018-02-28" version="1">MGMGNLLDLSRFKSFIADELKVSRHSIQALVIGEHGENMLPLVRYSSIAGIPLMHLISAEKAKEIVEKTRKVAAEVIALKGATIYAPANAVAEMLDAIARDRRAIMPVCAYPDGKYGIKDICIGVPAMIGGEGIEEIVEVELNDEERAIFDNGVKAVREAVRSVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDG7</accession>
    <name>A0A2H5VDG7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74601">
        <property type="protein sequence ID" value="GBC74601"/>
        <property type="gene ID" value="HRbin05_00645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003847">
        <property type="entry name" value="Put_antitoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02697">
        <property type="entry name" value="VAPB_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="81" mass="9254" checksum="B30860BDE955608C" modified="2018-02-28" version="1">MTKVISLSDEAYQALKKIKGKDESFSDVILRLIKEAAKRPLSEFAGRWMGSDIDLVFDMVLKEREESSSREVEIHSGYTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDH7</accession>
    <name>A0A2H5VDH7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74611">
        <property type="protein sequence ID" value="GBC74611"/>
        <property type="gene ID" value="HRbin05_00655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030688">
        <property type="entry name" value="MeTrfase_MtrA/MtxA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04208">
        <property type="entry name" value="MtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="164" mass="17730" checksum="59E611D9C3BBAF86" modified="2018-02-28" version="1">MVRGLIGDLAGKVCKFILPIKYDIFIGSTSSSIALCTLASIDLLLEVSRSDLMNSIAVAGRLLSENKGIDALVRYVVADKRIRCIVLAGKDSKGHLAGQSLLALWLNGIDDEGRIIGSMGKDAVLTLIKDEVDEFRAQISTMIDMRGVTDVDSIRKCIMVDTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBB4</accession>
    <name>A0A2H5VBB4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="5">2.7.7.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pnp</name>
        <name evidence="5" type="ORF">HRbin05_00005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eIF-2-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73977">
        <property type="protein sequence ID" value="GBC73977"/>
        <property type="gene ID" value="HRbin05_00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04452">
        <property type="entry name" value="S1_IF2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044126">
        <property type="entry name" value="S1_IF2_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024055">
        <property type="entry name" value="TIF2_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024054">
        <property type="entry name" value="TIF2_asu_middle_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011488">
        <property type="entry name" value="TIF_2_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10602">
        <property type="entry name" value="PTHR10602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07541">
        <property type="entry name" value="EIF_2_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110993">
        <property type="entry name" value="SSF110993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116742">
        <property type="entry name" value="SSF116742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="4">
        <location>
            <begin position="13"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC73977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="268" mass="30481" checksum="1E17044892405F94" modified="2018-02-28" version="1">MRYKQDQALPEEGDLVMATVQEVFPQGAYVTLDEYDGLLGFLHVSEIATGWIRNIEHYVRPKQKVVLKVIRVNRARREVDLSLRQVTNEERRLKVMEVKRAEKANAFLRIIRERCSSMSDDEFDRCVSLIKDEYPMLYDMFEDVARKGTKVLEKLNLPKEIVDAIVDISSKIPLPKVEVGGIMEITCSRSDGIDVIKDVLTSVEGNKHNADVSITYLGAPKYRLVISAENFKVAEKALNSILQSVQKGIEKKGGTFKFTREESRKGVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBB7</accession>
    <name>A0A2H5VBB7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methionine adenosyltransferase</fullName>
            <ecNumber evidence="6">2.5.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">metK</name>
        <name evidence="17" type="ORF">HRbin05_00013</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73985">
        <property type="protein sequence ID" value="GBC73985"/>
        <property type="gene ID" value="HRbin05_00013"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="13" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="112"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="229"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="GBC73985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="379" mass="41602" checksum="043F8D634C6F0C8D" modified="2018-02-28" version="1">MKQLFTSESVTEGHPDKVCDHIADAILDEYMAQDKYSRVAVEILATAGLMVVAGEVTSSAHVDIPRVVRQVVQDIGYGSSDSGLDIERCKLITSLHEQSPDIAVGVVRGDSIGAGDQGLMFGYACDETEELMPMPIMIANKLCMRLAELRKKNVIPWLRPDGKSQVTVEYEDGVVNGIKAIVLSAQHAPDVDIETVRKELIDKVIMPVCNELIDSSTRFYINPTGRFVIGGPAGDTGLTGRKVIVDTYGGACKHGGGAFSGKDPTKVDRSASYMMRYIAKNIVASGLAKRCELQVAYAIGVAEPIALYVNTFNTGKVSDEELSAYIMRNFNLTPAGIIDFLQLRRPIYRKTAVYGHFGRNEPEFTWERLDSVDLFRRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBD1</accession>
    <name>A0A2H5VBD1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Homoserine kinase</fullName>
            <shortName evidence="10">HK</shortName>
            <shortName evidence="10">HSK</shortName>
            <ecNumber evidence="3 10">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">thrB_1</name>
        <name evidence="10" type="synonym">thrB</name>
        <name evidence="13" type="ORF">HRbin05_00024</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="3 10"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73996">
        <property type="protein sequence ID" value="GBC73996"/>
        <property type="gene ID" value="HRbin05_00024"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="5 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="11">
        <location>
            <begin position="106"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="12">
        <location>
            <begin position="245"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GBC73996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="337" mass="35564" checksum="12F65FB49121C9C8" modified="2018-02-28" version="1">MLRRALYRQVKVSAPASTANLGPGFDVFGLAIDAYSDEVELVLEDDKSDSYSDSSSSSISSIDSLTIEVHGSSMNAEHIPEAAEHNSAGLALLSMMKAYNIRDRIRVRVNKGIPAGYGLGSSAASAVAAVKALDVMYDLGLDDVTLLRHAAQGEIASAGTVHYDNVAASLLGGFVIVRQEPLYTVKVEPPEDLLLCVATPKVDVPKGKTGVARSVLPEKIMLRQMVSNVANASMLVAGFLMKDTRLIADAMMRDVVVEPARMHIIPAYASVKKAALDAGALAVTISGAGPSILIVVDANDNVKDVVDAVDTAYSREGIECYVKVCKIAGGVSVLECR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBD7</accession>
    <name>A0A2H5VBD7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent RNA helicase DbpA</fullName>
            <ecNumber evidence="3">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dbpA_1</name>
        <name evidence="3" type="ORF">HRbin05_00017</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73989">
        <property type="protein sequence ID" value="GBC73989"/>
        <property type="gene ID" value="HRbin05_00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013701">
        <property type="entry name" value="DEAD/DEAH_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017170">
        <property type="entry name" value="Lhr-like_ATP-dep_RNA_helic_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08494">
        <property type="entry name" value="DEAD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037307">
        <property type="entry name" value="Lhr-like_helic_prd"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="57"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="279"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC73989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="1023" mass="116092" checksum="FD5720A3F3124A70" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBE7</accession>
    <name>A0A2H5VBE7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">7-cyano-7-deazaguanine synthase</fullName>
            <ecNumber evidence="1">6.3.4.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">queC</name>
        <name evidence="1" type="ORF">HRbin05_00027</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.20" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73999">
        <property type="protein sequence ID" value="GBC73999"/>
        <property type="gene ID" value="HRbin05_00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01995">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018317">
        <property type="entry name" value="QueC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42914">
        <property type="entry name" value="PTHR42914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06508">
        <property type="entry name" value="QueC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006293">
        <property type="entry name" value="ExsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00364">
        <property type="entry name" value="TIGR00364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC73999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="244" mass="27408" checksum="59BD5B76DD1D3A0E" modified="2018-02-28" version="1">MDKAICILSGGLDSTCIAAYLKEKGYELYAITFYYGQKSRMEVERARSIAEYIRVREHRIVDIGFMKSLYKDSNILTGDGSIPDRFDYSIVVPARNAIFLTIAGAWAFSINAALVAYGAHTDDEKNYPDCRTVFAKSMEHVLNLAEMDGIEQGLRKRLRIWSPAVEGLSKADLVRAGYRMLGNLLFETWSCYTDGIEVEVDGKTIKVQCGSCESCMNRIRAFKEAGIEDKTLYAVLDLNKMLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBF0</accession>
    <name>A0A2H5VBF0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aspartokinase</fullName>
            <ecNumber evidence="3">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">thrA</name>
        <name evidence="6" type="ORF">HRbin05_00053</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the aspartokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74022">
        <property type="protein sequence ID" value="GBC74022"/>
        <property type="gene ID" value="HRbin05_00053"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00656">
        <property type="entry name" value="asp_kin_monofn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="5">
        <location>
            <begin position="336"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="5">
        <location>
            <begin position="413"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="478" mass="52032" checksum="11CE3B4871D9A151" modified="2018-02-28" version="1">MKFGGNAVADVERIRHVARDIVKQMQEKREEKKGNDPFSNSNQIVVVVSAIKGVTDDLIKVCDSIMGGECSRVDSIIHSIEERHRSIASNLCNDGSYTSELSSIIDALIKEMNDLLKGMMLLNEVTPRSRDYLLSFGERLIAPMLCYALKDVGVEAEYLTGKDAGIVTDSNYGDARPLMDTTRLRVRHKIMPMLEHGVVPVVTGFIGSDQHGNITTLGRGGSDYTATIIASCIDADEVMLWTDVDGLMTADPKIVKDAQVLREVSYAEAMEMALFGAKYLHPRALEPILDKGIPIRIRNVFNLECQGTTIMKSPTAYPSKIVKAVTAIRNVSLIDVRGSSMVGSPGTAGRIFNVLGEHRINIIMISQGPSESSISMVVRKSDLDKAVNALELNLLGRLIKGINVTDDVAIIAVVGAGMRGTKGVAARVFKAVADRGINVIMIAQGSSELNLAFVVEDRYAEGAVKALHDEFELDRINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBF3</accession>
    <name>A0A2H5VBF3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00056</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74025">
        <property type="protein sequence ID" value="GBC74025"/>
        <property type="gene ID" value="HRbin05_00056"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10441">
        <property type="entry name" value="GIY-YIG_COG1833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002837">
        <property type="entry name" value="DUF123"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37460">
        <property type="entry name" value="PTHR37460"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01986">
        <property type="entry name" value="DUF123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="28"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="148" mass="16616" checksum="CFDD96997850D93D" modified="2018-02-28" version="1">MVVSEYAMNGVYIILISVDSACRHRIRIGSLGMMMLTPGIYAYVGSAMNSLKTRIKRHASISKRLRWHIDYLTTHGCAKVINAVYAATDRRVECVLSCYLAEQHHAPFKGFGSSDCSCYSHLYLVNGLDDVLAVFKRCNLDADVLYEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBG8</accession>
    <name>A0A2H5VBG8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74028">
        <property type="protein sequence ID" value="GBC74028"/>
        <property type="gene ID" value="HRbin05_00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="119" mass="13463" checksum="99196A0F1B66D211" modified="2018-02-28" version="1">MKYCNKDQFLPSITFSSRTNTLIITALDRRDSTNNTLWRSTSYHCHLNVNTCTSSSHWSTSSKGPQSTNADTEGTQTKTHIGSYYSVTTGSREAYNVWLDNGTVNLDSKLRIWLDRTTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBH4</accession>
    <name>A0A2H5VBH4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00064</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74033">
        <property type="protein sequence ID" value="GBC74033"/>
        <property type="gene ID" value="HRbin05_00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="129" mass="14688" checksum="1E923D60860BD0D9" modified="2018-02-28" version="1">MKRMRHRRGVTIIMVLLALGSSYNILVGILTLSEYYASELFSAASTGAAMKFTLASFALALIYGLYKRKGWALFLSILFMCFGLLDSIWTMYIQMLLGYPYTIAVVAIALFSLGIYYLSRRSVREEFYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBH5</accession>
    <name>A0A2H5VBH5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TFIIS-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HRbin05_00051</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74020">
        <property type="protein sequence ID" value="GBC74020"/>
        <property type="gene ID" value="HRbin05_00051"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012164">
        <property type="entry name" value="Rpa12/Rpb9/Rpc10/TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006288">
        <property type="entry name" value="TFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001222">
        <property type="entry name" value="Znf_TFIIS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11239">
        <property type="entry name" value="PTHR11239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01096">
        <property type="entry name" value="TFIIS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005586">
        <property type="entry name" value="RNApol_RpoM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00440">
        <property type="entry name" value="ZnF_C2C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01384">
        <property type="entry name" value="TFS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00466">
        <property type="entry name" value="ZF_TFIIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51133">
        <property type="entry name" value="ZF_TFIIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIS-type" evidence="6">
        <location>
            <begin position="59"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR005586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="102" mass="11705" checksum="3E72A2C61D72CE4A" modified="2018-02-28" version="1">MRLVQSKGNDGTMHLICRKCGYDEMARNPSTSTSKIKDEKPLIQVVGEEEADISVMPTIKITCPKCGHDTAVWWMLQTRSADEPTTQFYRCVKCNHTWRHYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBI2</accession>
    <name>A0A2H5VBI2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74039">
        <property type="protein sequence ID" value="GBC74039"/>
        <property type="gene ID" value="HRbin05_00070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="185" mass="22347" checksum="8058E378B8121793" modified="2018-02-28" version="1">MNVLKWRSRRNSRLVEKVITCIGTDSKSKEDLIKLFNDVHKLTVIMNRLKRDNIICSSTNYPCRYSLTQYGRWLFICYMLNIRPVQLVILALLYNNYNRSIYKGLEWIVPVIKHEIIKLLSSFSYDDEYAWKQVKILCKRGLCRYYGREGIVLEPSTYYMLREWHHEIYALYEHLRSVNRYEVCI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBI8</accession>
    <name>A0A2H5VBI8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Octaprenyl diphosphate synthase</fullName>
            <ecNumber evidence="2">2.5.1.90</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ispB</name>
        <name evidence="2" type="ORF">HRbin05_00085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.90" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74054">
        <property type="protein sequence ID" value="GBC74054"/>
        <property type="gene ID" value="HRbin05_00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106350">
        <property type="term" value="F:octaprenyl pyrophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="325" mass="36560" checksum="462157B6F4E3E1BC" modified="2018-02-28" version="1">MDIIEYWHITKPKIDEGIARLLPLFIERMPSEYASVLKESIEGGKRARGTLTCLVCQALGGRLEDALPRAVAIEYIHAATLIHDDYVDLDTVRRSRPAIWTLEGSRRAVLFGDLILSYMINMMSDMSRDDAKAVAEAIAAVARGAFQEPLNPMLLVDEITSGRFPSGLYDVIIKLKTGALFGAASKLGAIAANRLEMGERVYNYGSRCGEAFQIADDLREVLRIVETGKANVHKIITLVPACLYYYSDSIKEILDMIMGRHIDIASIVLERWVPLIEHMSNDIDVRLNLALKEIEDLEDNEYVQILRQAPRHMVRLMLEQKTVET</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBJ2</accession>
    <name>A0A2H5VBJ2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans, octacis-undecaprenol 4-epimerase</fullName>
            <ecNumber evidence="2">5.1.3.26</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gnu</name>
        <name evidence="2" type="ORF">HRbin05_00080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.26" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74049">
        <property type="protein sequence ID" value="GBC74049"/>
        <property type="gene ID" value="HRbin05_00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="323" mass="35995" checksum="55E11DD5B28A073E" modified="2018-02-28" version="1">MRILVTGATGFIGRRLVRRLINGGHEVTCLVRSDGAVTNPKTIGAKECIVADITNRESVMKAIGIAKDIDVLIHLAALNPLIKDRRLQYDVNINGMRNLIDAIVSARLTLKRVIYAQGMGVFGNVHGAIVDEDSQYRPETWFTRLRSDAERMLWDASKDAGFSISIAILGDVYGNGGWFTNIMVKGLIKSIFGLGFMIPGAGDYYRCFIHVDDAVDALALMAEVDYAGNERFIVCDDEPCMFREFVYYTADMLGVKRPPRIPLWLARLFLGSDMVDTLTASVRASNTKVKRMLNLMLRYPDYRVGVRSVVDEIRSVSGNRLAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBJ3</accession>
    <name>A0A2H5VBJ3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00084</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74053">
        <property type="protein sequence ID" value="GBC74053"/>
        <property type="gene ID" value="HRbin05_00084"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="58" mass="6495" checksum="211C1F0879EDD61E" modified="2018-02-28" version="1">MNTFILYKEGKMIRRVDIVGEGVDEDDPIVRALLSVVRTKGDSVVFKDISVDAVREAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBJ5</accession>
    <name>A0A2H5VBJ5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HRbin05_00103</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eL38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74072">
        <property type="protein sequence ID" value="GBC74072"/>
        <property type="gene ID" value="HRbin05_00103"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002675">
        <property type="entry name" value="Ribosomal_L38e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038464">
        <property type="entry name" value="Ribosomal_L38e_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01781">
        <property type="entry name" value="Ribosomal_L38e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="64" mass="7485" checksum="95B4123FBCE1F522" modified="2018-02-28" version="1">MPRQVFSKDELLKLVEGAEECRVVRRGDKVKIKVRRARYLYTYVASSSEADEILSRIKVEKVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBJ6</accession>
    <name>A0A2H5VBJ6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00071</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74040">
        <property type="protein sequence ID" value="GBC74040"/>
        <property type="gene ID" value="HRbin05_00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="296"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="601" mass="68184" checksum="2BBAC7C95C627020" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBK4</accession>
    <name>A0A2H5VBK4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">30S ribosomal protein S28e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps28e</name>
        <name evidence="4" type="ORF">HRbin05_00114</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the eukaryotic ribosomal protein eS28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74082">
        <property type="protein sequence ID" value="GBC74082"/>
        <property type="gene ID" value="HRbin05_00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04457">
        <property type="entry name" value="S1_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00292">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000289">
        <property type="entry name" value="Ribosomal_S28e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028626">
        <property type="entry name" value="Ribosomal_S28e_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10769">
        <property type="entry name" value="PTHR10769"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01200">
        <property type="entry name" value="Ribosomal_S28e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00961">
        <property type="entry name" value="RIBOSOMAL_S28E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="70" mass="7966" checksum="DAFD93DC34024BD0" modified="2018-02-28" version="1">MSREEEKLTPAEVIQIVGRTGIAGEITQVRVRILEGRDKGRIIARNVKGLVRLGDILMLRETEREARKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBL3</accession>
    <name>A0A2H5VBL3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc transporter ZupT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">zupT</name>
        <name evidence="2" type="ORF">HRbin05_00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74078">
        <property type="protein sequence ID" value="GBC74078"/>
        <property type="gene ID" value="HRbin05_00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="384"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="403" mass="43923" checksum="90615E9105A45FE1" modified="2018-02-28" version="1">MVILTVIPILLLTGIIYYITYTPIFDYGEPLPKIVIERVEFKPEVIVVYVRNIGQDTVTIAQADIDDAPIDAIIKPTNVLTRLSSAQLMINYRWIEGRPYEIGITTSDGTRFASSIEIATLTPEPDSEQLFYFALLGIYVGVIPVALGFLWFPSMQRVREHWNEFFLSITAGLLVFLAIDAIVEAFEIVDKFVVMNNSKVLIPMIMISTFLFLLLTVNKAGDSSYNDGNISLTLNTPDNITTNNNKDDVVTTNHNLRLHIAYMISVGIGLHNLGEGLAIGAALAVGAIALSKFLIIGFTIHNSTEGFAIASPLVRSKVKIAHFAMLGMIAGIPTIVGTWIGGFINIPIVSVVFLAVGAGAILQVVYAIFGLMSSKMSVAILSKYNIVGLVTGMLVMYLTSLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBM0</accession>
    <name>A0A2H5VBM0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">infB</name>
        <name evidence="9" type="ORF">HRbin05_00111</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74079">
        <property type="protein sequence ID" value="GBC74079"/>
        <property type="gene ID" value="HRbin05_00111"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_A">
        <property type="entry name" value="IF_2_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029459">
        <property type="entry name" value="EFTU-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004544">
        <property type="entry name" value="TF_aIF-2_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14578">
        <property type="entry name" value="GTP_EFTU_D4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00491">
        <property type="entry name" value="aIF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="8">
        <location>
            <begin position="3"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="76"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="592" mass="65808" checksum="749836C72358B815" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBN6</accession>
    <name>A0A2H5VBN6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Archaetidylinositol phosphate synthase</fullName>
            <shortName evidence="1">AIP synthase</shortName>
            <ecNumber evidence="1">2.7.8.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pgsA</name>
        <name evidence="3" type="ORF">HRbin05_00145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of archaetidylinositol phosphate (AIP) from CDP-archaeol (CDP-ArOH or CDP-2,3-bis-(O-phytanyl)-sn-glycerol) and 1L-myo-inositol 1-phosphate (IP or 1D-myo-inositol 3-phosphate). AIP is a precursor of archaetidyl-myo-inositol (AI), an ether-type inositol phospholipid ubiquitously distributed in archaea membranes and essential for glycolipid biosynthesis in archaea.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>1D-myo-inositol 3-phosphate + CDP-2,3-bis-O-(phytanyl)-sn-glycerol = CMP + H(+) + saturated 1-archaetidyl-1D-myo-inositol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:36823"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58401"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:74004"/>
            <dbReference type="ChEBI" id="CHEBI:74006"/>
            <dbReference type="EC" id="2.7.8.39"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="1">Binds 2 Mg(2+) or Mn(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.39" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74112">
        <property type="protein sequence ID" value="GBC74112"/>
        <property type="gene ID" value="HRbin05_00145"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02242">
        <property type="entry name" value="AIP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044270">
        <property type="entry name" value="AIP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="207" mass="21939" checksum="317F519D3CB7B3F1" modified="2018-02-28" version="1">MLLNKIRKDIEPMMNRIGVGFAATGLSPNALTLIGFALAVLAGFLYALQSMLEYAYLYAGIVLLISGFFDIVDGSVARVTGRVSRAGAFLDSTLDRVAEVAIYTGIVLSSKVNPALVILALALSLLVSYARARAEGVGVELKGIGVGERAERLLLLSTFSIASIIISMELMQYGLIIIVVLAAITFIHRVLAVLNAMAQGSSSHPQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBQ0</accession>
    <name>A0A2H5VBQ0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">pyrG</name>
        <name evidence="13" type="ORF">HRbin05_00148</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74115">
        <property type="protein sequence ID" value="GBC74115"/>
        <property type="gene ID" value="HRbin05_00148"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="12">
        <location>
            <begin position="22"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="11">
        <location>
            <begin position="323"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="404"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="556"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="403"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="529"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="531"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="33"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="167"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="207"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="376"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="484"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GBC74115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="575" mass="64809" checksum="9954E64109690694" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBQ8</accession>
    <name>A0A2H5VBQ8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2070 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74132">
        <property type="protein sequence ID" value="GBC74132"/>
        <property type="gene ID" value="HRbin05_00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019204">
        <property type="entry name" value="DUF2070_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09843">
        <property type="entry name" value="DUF2070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="589"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2070" evidence="2">
        <location>
            <begin position="12"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="609" mass="66781" checksum="4AFF9B1688FEE6A1" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBR2</accession>
    <name>A0A2H5VBR2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00161</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74128">
        <property type="protein sequence ID" value="GBC74128"/>
        <property type="gene ID" value="HRbin05_00161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="334" mass="37139" checksum="4B8ECA6781399E54" modified="2018-02-28" version="1">MQEDRRSNSRHNKSDGVGISIAWRVLLFIHATLTLLISAMMIASYPLGAYLVFHTSMGSGYREPLDGFYMLVPLPIQIQASISIGDLFILLWCTYLLLFTLLLLSPKNMLSAILRLVRKGDDGYSSSSSNNSINSSSNHLITTIAWFSILVASSIAIDLLQNMLGIEMGSIEYEDRLKHFVDATTAPLREELGFRMILIGVPAYLFLARQGSTLLNVLWRPYEHLSRHGKSIHLLIVASALLFGLAHVLFSTGWSYGKVTQATLGGIILGWLYYRYGLHAAVIAHWAANYLPLTYLFAGDAFGSDIMLNMLELVLVSNGIVAISLRLRAYFKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBS1</accession>
    <name>A0A2H5VBS1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoheptose isomerase</fullName>
            <ecNumber evidence="2">5.3.1.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gmhA</name>
        <name evidence="2" type="ORF">HRbin05_00143</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.28" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74110">
        <property type="protein sequence ID" value="GBC74110"/>
        <property type="gene ID" value="HRbin05_00143"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="1">
        <location>
            <begin position="21"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="317" mass="35009" checksum="914C63B27CF1B167" modified="2018-02-28" version="1">MSTLDAYEQEVSYQVEDIPMLMQEMKGRWLSKEEQLNTLITGSGDSFAAAMLAERLSGFRIQCIDPFELLSMIASRRILYIVSVSGSTRAVLDAMDRAHRHGMKVVAITANAESKLARGADSTILIRFKRTGMLTAGSIGFTASLVASASLAVNMDDVSVDVKDVFSKASDDAGGIVLAEHNYIVGDVLTYPLAVYGSAKLYEVLGARASYCRLEQFCHMEVFSLKEGDKVLILSSEEKARMLADGLRSNGIDATLLEYCNNEDRCNGRYEDETLSRLLYYTFLLQITVLNNAKRLGLRECAFVNHRLLGLSSSLIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBT0</accession>
    <name>A0A2H5VBT0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74145">
        <property type="protein sequence ID" value="GBC74145"/>
        <property type="gene ID" value="HRbin05_00178"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="53" mass="6304" checksum="D0FFE17DFD815AAA" modified="2018-02-28" version="1">MVECVRCHRDTNEFVLVPVEQKVYIICHDCVREIIRKYVESIKDKGFSDIDMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBU8</accession>
    <name>A0A2H5VBU8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74164">
        <property type="protein sequence ID" value="GBC74164"/>
        <property type="gene ID" value="HRbin05_00198"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="31"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="239" mass="28589" checksum="D03E7CF2B7390DBC" modified="2018-02-28" version="1">MLSNEELKKKILDMLEQDKEFRHAVAGVIGYKEILDRIARVEEELRNLREETNKLREETNRLRQDMQEGFRRHDEELKRHWESIEKLRQDMIEGFKRHDEEFKRIDKRLRSIESYMEKTSLTLEEEARDVIQYMLREKGLTLNISRLELPDIEIDIYGVDTEYCIVGEVKTRASSNLVERVDKDIELLCSRYPQYIRKKLIKVIYAMQITQDALNEGNKRNIWLVTAKGELTSLKIVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBU9</accession>
    <name>A0A2H5VBU9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 6">Histidinol dehydrogenase</fullName>
            <shortName evidence="6">HDH</shortName>
            <ecNumber evidence="6">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hisD</name>
        <name evidence="11" type="ORF">HRbin05_00200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74166">
        <property type="protein sequence ID" value="GBC74166"/>
        <property type="gene ID" value="HRbin05_00200"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="4 6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="353"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="388"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="442"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 9">
        <location>
            <position position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="461" mass="49884" checksum="5BB86AD36035485F" modified="2018-02-28" version="1">MRRVHSVDGNRMKNNSTPIRVERLDVDPAYAADMLRHKVVMDEERVNRIRSIINDVKVRGDAAIRDYTLKFDGVDLGSTPLRVAREEIDHAYTLASKEEVEALKAIRCRLEEVERAFLSCIKDMHIMLGSSKVSRVFKPLRSVGCYIPGGKARYASSMLMCVVPARVAGVKRVIACTPPTPNTNGKGKGKGSVDPLTLIAADIAGVDEVYRVGGAQAIAAMAYGSESIKPVSKIVGPGGLAVTIAKHIVSSSVAIDMLAGPTELLVVADGTADPRYIALDLIAQAEHAPDTLCGLITWSDTLAYKVADELTSLLPNVSRGEIVRESLSSNGFIAICKDEKYAIEFANEFAPEHLQVMVGDEVKHRIIEGIDSAGMMLIGNNSPSPASDYYTGTNHVLPTMGSAKARASLTCLDFLKPLSIVELSREDLKDIAGVVKHIARAEGLENHYRAVESRLSIYLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBV8</accession>
    <name>A0A2H5VBV8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative adenylyltransferase/sulfurtransferase MoeZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">moeZ</name>
        <name evidence="2" type="ORF">HRbin05_00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74176">
        <property type="protein sequence ID" value="GBC74176"/>
        <property type="gene ID" value="HRbin05_00210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="44"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="388" mass="41753" checksum="337D2C447E0C74D7" modified="2018-02-28" version="1">MLEVTVKGMAMGSGVKEMEEQMGREVSRERRKVTELSEDEVERYSRQIMLDSIGYEGQLRLRNARVCITGAGGLGSPIAMQLTAMGVGYIRLVDRDVVELSNLHRQMLYTDADIGKVKVEAAASRLKAINPSVDVEPLAVSINEGTADDVVKGCDLVIDGLDSIDARYALNDACVRAGIPYVYGGALGMLGSACTVLPGRSACIRCIFPELSDDEMPTCSIEGVHPSILYMVSAVQVSEAVRIITGQEPVLLNKLLYIDLNDLSFSTIDVSRNEHCICNGINRGKRVVATTTASGSIVFKVEELCGRDMGKRTFSITPKGILAIDLDAVARKASSLGFKEKSRGEMGITLVSDGRSFSVLRSGAAVVVGVESEDAALNLYNAMVEVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBW2</accession>
    <name>A0A2H5VBW2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sulfur carrier protein CysO</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">cysO</name>
        <name evidence="1" type="ORF">HRbin05_00209</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74175">
        <property type="protein sequence ID" value="GBC74175"/>
        <property type="gene ID" value="HRbin05_00209"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="100" mass="10565" checksum="4D2608019FB9AA75" modified="2018-02-28" version="1">MARVEVTIPSVLNKNAGERKVSVEADTLKDAIDSLVKIMGNDFARKVLDSNGKPKALINIYINGRNSRFSGGLDARLNDGDSVVILPAVAGGNSKGYGYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBY8</accession>
    <name>A0A2H5VBY8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">dnaK</name>
        <name evidence="7" type="ORF">HRbin05_00247</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Acts as a chaperone.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74212">
        <property type="protein sequence ID" value="GBC74212"/>
        <property type="gene ID" value="HRbin05_00247"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="560"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="459"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="584" mass="63788" checksum="D2670E4B5E207052" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBZ9</accession>
    <name>A0A2H5VBZ9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hydroxypyruvate reductase</fullName>
            <ecNumber evidence="5">1.1.1.81</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HRbin05_00254</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.81" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74219">
        <property type="protein sequence ID" value="GBC74219"/>
        <property type="gene ID" value="HRbin05_00254"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016618">
        <property type="term" value="F:hydroxypyruvate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="3">
        <location>
            <begin position="7"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="4">
        <location>
            <begin position="109"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="312" mass="34309" checksum="B66635FB6F57B2A9" modified="2018-02-28" version="1">MQKVPRILVSDVMDSNGIEVMRRNGLQVDYKPDIKHEELLATIKDYNILVVRSRTKVRKDVIDAAQNLKIIARVGVGLDNIDVEYAKSKGIKVVNAEEAAMSAVAELVIGLMICLARGIVRADTTMKQGRWIKSELMGIELRGKYLGIIGMGKIGTRVARLARALGMNIIAYDVVKIDPMLVRELGIVTTDLDTLLKSSDFVTLHVPLNDSTRHMIDASRLAMMKSSAYIINTARGAVIDEEALLNALKEGRIAGAALDVYEIEPPTNMELIRLPNVICTPHIGAQTREAQALAASIIAEKVVQLTRELYIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC04</accession>
    <name>A0A2H5VC04_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00252</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74217">
        <property type="protein sequence ID" value="GBC74217"/>
        <property type="gene ID" value="HRbin05_00252"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="208" mass="24081" checksum="DB3A6A8A65EE4546" modified="2018-02-28" version="1">MYHSSRESVDEYKVTCIEFIRDISNDYKDWVKRYNLDEEESAWRLEMIDNVVKVSSAWIARYGDTIRKIDVIKDDGINKMAEFTAGYPFYLQVYVDGQLRYAEHKAGMIELEVKARAREEGRSVGITMYNRRMNEIFQLLTATEVSDAVSVLGYDDRLMNAIDAKVILDASKCRESDLISITVVVGEYDERDGLELDKRGFTTLIRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC05</accession>
    <name>A0A2H5VC05_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fumarate hydratase class II</fullName>
            <ecNumber evidence="3">4.2.1.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fumC</name>
        <name evidence="3" type="ORF">HRbin05_00258</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74223">
        <property type="protein sequence ID" value="GBC74223"/>
        <property type="gene ID" value="HRbin05_00258"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="1">
        <location>
            <begin position="10"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="2">
        <location>
            <begin position="405"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="456" mass="49919" checksum="002AA092407134A3" modified="2018-02-28" version="1">MYRVDRDSLGEVKVPNDAYYGPFTVRALEHYNATAQRMHVNMVKAYVMIKRSAALANMQLGALEKERGEAIVRACDAILAGELLDQFPIDALNSGAGTAFNMNVNEVIANKALELLGRSKGDYSYLHPNDHVNMSQSSNDTFPTALHLAILMSSKDLVAALDRLISSLHRKGEEFKHILKIGRTHLMDALPVTLGSEFHAYAHAIEDARRYLLDALGELKYIALGGTAVGTGANAPKGYRELAIRYLAEISSIDLKPARDMQYALQSRLGVAYVSSCLRNLALELIRVANDIRLMASGPLAGLGELTIPAVHAGSSIMPGKVNPSLAECLDMICFNVVGNDLSTALAVQAGQLELNVMLPVMARCVLDSMDMLSRFIPVFVEHMLDGLKADEQRLKTNVENNPIMVTLLSPYIGYIKAAELYKEALKEGVSIKHLVVRKGLMDEKRVDEIIRDAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC16</accession>
    <name>A0A2H5VC16_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-phospho-L-lactate transferase</fullName>
            <ecNumber evidence="3">2.7.8.28</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cofD</name>
        <name evidence="3" type="ORF">HRbin05_00268</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.28" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74233">
        <property type="protein sequence ID" value="GBC74233"/>
        <property type="gene ID" value="HRbin05_00268"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07186">
        <property type="entry name" value="CofD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01257">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010115">
        <property type="entry name" value="FbiA/CofD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43007">
        <property type="entry name" value="PTHR43007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01819">
        <property type="entry name" value="F420_cofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="330" mass="36468" checksum="CBADD063ED5D9334" modified="2018-02-28" version="1">MDKIVVLAGGTGSVKLARALYRLKSNSNTADTSSRVDNNSKNSNNSKQDMHLSIVCNVGDNIWMHGLYICPDLDTIVYGLAGLLDREKGWGVSNDTFNCLAQLAKLEGEQWFMLGDKDLAIHIIRSMMLREGKRLCEITGYLCSRLGIDAMVIPASDDHIETRIITNAGDIHLQEFWVKNKGMLDVHGIVYKGIEHVRACSNALHAIEEADRIIVAPANPVSSILPILAIRELGDAVRRRRDVCVAVSPIIGSRPVSGPAAKYMKALGYDVSPVSIAEMYRDVASTLVIHESDIALMDEIKAKDMDVYATDILMDDEEDEVRLARYLLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC19</accession>
    <name>A0A2H5VC19_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00154</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74121">
        <property type="protein sequence ID" value="GBC74121"/>
        <property type="gene ID" value="HRbin05_00154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="32" mass="3685" checksum="606E14E807246135" modified="2018-02-28" version="1">MGEWIDGCVGGVKMMAMRRMKEEREKRGRGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC33</accession>
    <name>A0A2H5VC33_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">High-affinity zinc uptake system ATP-binding protein ZnuC</fullName>
            <ecNumber evidence="5">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">znuC</name>
        <name evidence="5" type="ORF">HRbin05_00283</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74248">
        <property type="protein sequence ID" value="GBC74248"/>
        <property type="gene ID" value="HRbin05_00283"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="289" mass="32420" checksum="BBF345F08A7BE3CE" modified="2018-02-28" version="1">MKGMAILKVRDLSVRYGSTSILEDVNMDVEHGDILGILGPNGAGKTTLFNSILMLQEHEGTVSIFGYSNHTRRYVLPFIGYLPQRFSVDHNFPATVEDLIYTGLISIRYMQKNAYLLERNGYRWSYNPRLSNRERIDEALRMVGLEHARGKRIGMLSGGELQRALIAKILVSRPLMLILDEPFTALDQDAQTKLFNILNTLNEEMGVTIILAAHDLMLLMKLAKHIACIDRRIFFHGSKAECIASDLLRLYSEHAMHMHMKEHKEIGTAGYVGSSSSNSSSSSSSRSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC44</accession>
    <name>A0A2H5VC44_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zinc_ribbon_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00298</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74263">
        <property type="protein sequence ID" value="GBC74263"/>
        <property type="gene ID" value="HRbin05_00298"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zinc_ribbon_2" evidence="1">
        <location>
            <begin position="269"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="294" mass="32933" checksum="202C665FC752C3C2" modified="2018-02-28" version="1">MGKTERFTGLNVDLERLATRVQMYLQENGFEVAYSKDPTAPPSWFFIQARKISTLRSIAGARRSTDITIKGKPDDFEVTISTGEWGKNMLSSAPLFIVPIVGITATVAKLYTAKSFESNLWKYIKDQIRFLSNSVVQVESKERLDKRVYDCDYVEGYPGWKDSVEGGRLVLERSRDGNNRVVFTSSKGDIVIPASSIEQAQIIARRKGLHEHDLMIQMVVKQNGKSIKPVFNLKDEIIAGVLAGINELVSEERAMRSIEHASVITDVKYCIKCGAEIPKNARFCSQYGSPQEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC55</accession>
    <name>A0A2H5VC55_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PadR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00302</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74267">
        <property type="protein sequence ID" value="GBC74267"/>
        <property type="gene ID" value="HRbin05_00302"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="22"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="175" mass="20154" checksum="5F71F46CD386E0F0" modified="2018-02-28" version="1">MISEWLQRISGAVPKGFSRYYVLSLLNERAMTGKEIMEEAARRSNNLWKPSPGLVYPLLGKLLQEGLIEEDDYGRYRITGKGKAVLADVNVIQGIVRKQLDVMMHFSTLSMFIAKDILERITSLGSMLAANIDKMTQQERERYREFLLAQLRKLDESDAKRREQENRGKESIDVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC60</accession>
    <name>A0A2H5VC60_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00319</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74282">
        <property type="protein sequence ID" value="GBC74282"/>
        <property type="gene ID" value="HRbin05_00319"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="SSF102705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="268" mass="29719" checksum="ABB3F4C0B7705AC2" modified="2018-02-28" version="1">MDTEEIMHTALSLAGMDSIPADSAVHVKGKDIRKVLMCIDVEQSTIMLAKHLGYDAIIAHHPIGKAYIDFYKVLDRHVEFMLNAGIARGVAEEAVKELKERVMLRAHTSIYTHVTSFAEKVGMPLLNIHLPCDELMRRAILKSLEAGRVERVRDIASSVEQLDEFKKADTRVKVVHGDEDTRVKRYMLVVAAGTNGGYSVAKAYFDHGYDTVIYLHISPEDLARVKSSNLNGNLVILGHLAGDSLGMNMLADELTRKGLQVDKLGIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC69</accession>
    <name>A0A2H5VC69_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="5 9">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">hisA</name>
        <name evidence="11" type="ORF">HRbin05_00205</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9 10">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="5 9"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74171">
        <property type="protein sequence ID" value="GBC74171"/>
        <property type="gene ID" value="HRbin05_00205"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="240" mass="25920" checksum="CF3D28088C9D2C4E" modified="2018-02-28" version="1">MKIIPAIDLMDGKVVRLTKGDPSKQTVYSDDPLEVAKAWVREGADALHVVDLNATLSLATNHRAIVERISRSVSVPVQAAGGIRSFDAAVSMLEHVHAVVLATLAFKDEHALTKLLELYGYERIIVALDHEDGIVKIHGWRDSTGVSMEDALKHFSLLGVKRFLVTDTARDGTMLGLSNTSIKIMKDANRAGLEIIASGGIATLDDVKIARDAGAYAVILGKALYEGRIRVGEAKRLSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC70</accession>
    <name>A0A2H5VC70_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">30S ribosomal protein S4e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rps4e</name>
        <name evidence="9" type="ORF">HRbin05_00330</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the eukaryotic ribosomal protein eS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74292">
        <property type="protein sequence ID" value="GBC74292"/>
        <property type="gene ID" value="HRbin05_00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00485">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000876">
        <property type="entry name" value="Ribosomal_S4e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013845">
        <property type="entry name" value="Ribosomal_S4e_central_region"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038237">
        <property type="entry name" value="Ribosomal_S4e_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013843">
        <property type="entry name" value="Ribosomal_S4e_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11581">
        <property type="entry name" value="PTHR11581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00900">
        <property type="entry name" value="Ribosomal_S4e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08071">
        <property type="entry name" value="RS4NT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002116">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="186"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="249" mass="27953" checksum="997226976EF86E00" modified="2018-02-28" version="1">MVSIMGKKAGSNRLKRQMMPAFWQVPRKAYRFAIRPIPGPHPIDRCYPLGVLLRDVLKVVSNMRETEKVLHNGYVYVDGVKRYDVHFPVGLMDVVELQPLKKVYRLVPRDGLILKPIEIAEGEKMEKEKNLKICKVVRKHTVKGGRIQYTLHDGRNILDDPKLNGITINDSILIKVPGQEVIDTVKMEKGALALITAGDNAGTTGRIVEVKEGTITLPKRVVVESDSKRLEIPADIVIAIGRERPLLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC71</accession>
    <name>A0A2H5VC71_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74260">
        <property type="protein sequence ID" value="GBC74260"/>
        <property type="gene ID" value="HRbin05_00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027560">
        <property type="entry name" value="PEFG-CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04296">
        <property type="entry name" value="PEFG-CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="283" mass="30521" checksum="A2C525E169163DEA" modified="2018-02-28" version="1">MARYRSALIGTLVASMMLLAAPFAVYAQQQQITITLDKQSYSTGDTLKVTGKVPRVITGLDVIIQIMNERNNQAALTQVTPASDGSFSAEFKLGGPFMSNSGTYKVVVTYGDIQSSAEFAFTAQAQPTVREFSVKISGIQEDITLRGTITVGNVQSATLDQDFNSIVLQLSGINTDSKLTITVPSTVIRDEFRAQFMDVDFIAFSEETDAEIQANVTKHTADEATLEIDVPADISTLEIVIAPENIAVVPEFGVIAALILAAGIGTFIVVSRRQMVRIFPQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC78</accession>
    <name>A0A2H5VC78_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl22</name>
        <name evidence="7" type="ORF">HRbin05_00337</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="4 6">This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74299">
        <property type="protein sequence ID" value="GBC74299"/>
        <property type="gene ID" value="HRbin05_00337"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_A">
        <property type="entry name" value="Ribosomal_L22_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005721">
        <property type="entry name" value="Ribosomal_L22/L17_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11593">
        <property type="entry name" value="PTHR11593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01038">
        <property type="entry name" value="uL22_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="157" mass="18035" checksum="ED9F3B4E623934BE" modified="2018-02-28" version="1">MPEFDYTFKKQYDKSKHVRASIREVDISHKHAIEICNAIKGMKLEKAKEYLEKVVAKEIPVPFRHYHTKVGHRSELKGKNAFPAGRYPVKAAREILRLLANLEANSEYKGMDLDRVTIIHACAYPGVKIRKFMPRAFGRGSARFNILTHVELVASEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC81</accession>
    <name>A0A2H5VC81_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74270">
        <property type="protein sequence ID" value="GBC74270"/>
        <property type="gene ID" value="HRbin05_00305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="177" mass="19584" checksum="292C7D4E425ACAB2" modified="2018-02-28" version="1">MTTNIVNNVDLSKISALIEQGKKDRSALRKIIKLEGEWILDGSKGFQFRSEMAYEKGKQVLEIDSPTWLGGQGNRLGPMAYCIAGLTSCFIATFASVAASKGIRLRRLRVSSNCVVNFAKTLDVADEPITESINFDVDAEAENADKAKLEEILKLARERCPAVYSMEHVIKVNTTLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC99</accession>
    <name>A0A2H5VC99_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Divalent-cation tolerance protein CutA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cutA</name>
        <name evidence="2" type="ORF">HRbin05_00235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74201">
        <property type="protein sequence ID" value="GBC74201"/>
        <property type="gene ID" value="HRbin05_00235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004323">
        <property type="entry name" value="Ion_tolerance_CutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419">
        <property type="entry name" value="PTHR23419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03091">
        <property type="entry name" value="CutA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="107" mass="11980" checksum="14A08FDE6BA9C2B6" modified="2018-02-28" version="1">MVAMKGVILISTYPDEANALKAARGAVDSRLAACVNIAKIRSIYRWEGKVEDAEEYLALFKTTEDSLPRLKEFISSTHPYKVPEMVSIAMDSVSERYMAWMVESISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCA1</accession>
    <name>A0A2H5VCA1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable thymidylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">tmk</name>
        <name evidence="4" type="ORF">HRbin05_00364</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74326">
        <property type="protein sequence ID" value="GBC74326"/>
        <property type="gene ID" value="HRbin05_00364"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="3">
        <location>
            <begin position="5"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="197" mass="22666" checksum="45754F4DD84D388B" modified="2018-02-28" version="1">MLLVIEGPDKAGKSTQARMLNDTLTRMGYRCAMMSFPDYSTPIGKEIEAFLRGERDYPLQVKHMLLSANRWEKKDEVERLLASNDVVILNRYYQSNIVYGIANGLDMQWLEMLDRCLPKEDLVIVLHVTAEIALERARLNAMHRDMFESVELLKRVSLLYLELAGRYGWVVVDGGRGVEEVHRDVLSITLKHIQDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCA3</accession>
    <name>A0A2H5VCA3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Siroheme synthase</fullName>
            <ecNumber evidence="6">4.99.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">cysG</name>
        <name evidence="6" type="ORF">HRbin05_00360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; adenosylcobalamin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.4" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74322">
        <property type="protein sequence ID" value="GBC74322"/>
        <property type="gene ID" value="HRbin05_00360"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051266">
        <property type="term" value="F:sirohydrochlorin ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11644">
        <property type="entry name" value="Precorrin-6Y-MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012818">
        <property type="entry name" value="CbiE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="5">
        <location>
            <begin position="3"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="252" mass="28364" checksum="53AE9A53F2A87E36" modified="2018-02-28" version="1">MGKVYLVGVGPGGEWYITEIAKRLIERADVVVGYKHALNVIKNIVDKGYDEMEKSKGRSERVKGKKDIRMITLKTQDEVYAQLLDYLKGKDREEGEKGGREKVCCILFTGDPDFSESEIVDKLVSLFESNGIEVEIIPGISSVQVAAARSKVAIDRSSLITFHVTGSIDREKDALLNTLRAKRTVILLPRPWDFMPQHIGRFLRDEGIDVDAFNVDIYENLTLSNEKVTHCKLADIPDRDYSDLCVMVIKPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCA7</accession>
    <name>A0A2H5VCA7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74317">
        <property type="protein sequence ID" value="GBC74317"/>
        <property type="gene ID" value="HRbin05_00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="80" mass="9062" checksum="2432ECDC05D4713A" modified="2018-02-28" version="1">MGLLLRIYLLLSLLAFLMIAIVNGIVSMAMPDGPNFHYTHWILGRLTGAWSIDFIVDMLITALCIGLALTIVWINHYRYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCC0</accession>
    <name>A0A2H5VCC0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00348</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74310">
        <property type="protein sequence ID" value="GBC74310"/>
        <property type="gene ID" value="HRbin05_00348"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="61" mass="7303" checksum="7B3E7A2C9581BA59" modified="2018-02-28" version="1">MRCIICDMNFAFEKGKGISFRNKPICDECLLNLTIVFLDKYKEGIKRYLKQEIKLEHYNNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCC5</accession>
    <name>A0A2H5VCC5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00372</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74334">
        <property type="protein sequence ID" value="GBC74334"/>
        <property type="gene ID" value="HRbin05_00372"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="863" mass="94375" checksum="9889B77726D7C144" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCC6</accession>
    <name>A0A2H5VCC6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemotaxis protein CheW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cheW</name>
        <name evidence="2" type="ORF">HRbin05_00375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74337">
        <property type="protein sequence ID" value="GBC74337"/>
        <property type="gene ID" value="HRbin05_00375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="148" mass="16418" checksum="663F1EAD9E00678F" modified="2018-02-28" version="1">MMSSNILNLLLFKLEMSDGSAEYYAVDVDKIYEIRAMEKVTRIPDARIISGIMNLRGKIISVVDIKNILGYNSSVEPKRILIADVNGTMLGLMVDDVEQVAKVASDNIELDASILDNVSYIKGIIKMQDKLVVYLDIDKLFDMKGGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCE2</accession>
    <name>A0A2H5VCE2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00398</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74358">
        <property type="protein sequence ID" value="GBC74358"/>
        <property type="gene ID" value="HRbin05_00398"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="235" mass="26301" checksum="1CCF8FF53D4A3AE1" modified="2018-02-28" version="1">MLGLVFFTIYIVISSSASMLIPLLGIMYIPFLQYFDTSMVLRVAEALAPLTYAIVIGIGTTQGVIIGEAIVERFPRLTFHTRVASIALFILFAANAIANVLRFVSPKKIHTPPILNGSDGLAMVSKILDISNPTTLLTFSISILVFALLSMLRIRDYRRSFLLIISIVMAFITSALLFSDYKPSEFEVLLYALYQAGIVGGVALGTRRQLSNREIRFRYMRERWMGSSDNDSDYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCF7</accession>
    <name>A0A2H5VCF7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ATP-dependent RNA helicase DbpA</fullName>
            <ecNumber evidence="4">3.6.4.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dbpA_2</name>
        <name evidence="4" type="ORF">HRbin05_00419</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74379">
        <property type="protein sequence ID" value="GBC74379"/>
        <property type="gene ID" value="HRbin05_00419"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12089">
        <property type="entry name" value="Hef_ID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039686">
        <property type="entry name" value="FANCM/Mph1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041755">
        <property type="entry name" value="Hef_ID"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14025:SF20">
        <property type="entry name" value="PTHR14025:SF20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="46"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="361"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="585" mass="64837" checksum="9D3B06EF905DD005" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCF8</accession>
    <name>A0A2H5VCF8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74350">
        <property type="protein sequence ID" value="GBC74350"/>
        <property type="gene ID" value="HRbin05_00390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="85"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="102" mass="11458" checksum="D866349264849448" modified="2018-02-28" version="1">MMTPLRNIVYEKIRGARSITDVELMNMLAKEGFEFTKAELNKILLDLEILGLVRVGWISKDKRRIEVRDTEGKGRGKGEVGDEEMAAIEDGEDEGDDDNTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCF9</accession>
    <name>A0A2H5VCF9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00404</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74364">
        <property type="protein sequence ID" value="GBC74364"/>
        <property type="gene ID" value="HRbin05_00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="29" mass="2918" checksum="58D96384CCFE3BF1" modified="2018-02-28" version="1">MLLFSAIALFIIVSSGLFGGMKSISASGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCG7</accession>
    <name>A0A2H5VCG7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00429</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74389">
        <property type="protein sequence ID" value="GBC74389"/>
        <property type="gene ID" value="HRbin05_00429"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="210" mass="23849" checksum="8625957AFCA82E9C" modified="2018-02-28" version="1">MAISSYATNQSIHYLRYNRIKPINEIVEIIYMSSVEDEPKDVMVLSAIAKGYNTEEKIAKATGLSAFDVAMIVERLILHGLIVKKEKKGFLGKRKVELTMTEKGTRELQERRFELEQRWQRMVMLAEQGKRQEFEREALSMRSWIPIMLFMGIMDMMMWMTMLNMMNLAAQDYMPEQVPDAGAGSGGGDMGGDAGEGGGWDWGDFGDVNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCH0</accession>
    <name>A0A2H5VCH0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Peroxiredoxin bcp</fullName>
            <ecNumber evidence="5">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bcp</name>
        <name evidence="5" type="ORF">HRbin05_00433</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74393">
        <property type="protein sequence ID" value="GBC74393"/>
        <property type="gene ID" value="HRbin05_00433"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="7"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="152" mass="16705" checksum="69E7EEE1FE90836E" modified="2018-02-28" version="1">MGDGASIGVGSSAPDFTAESTQGRIRLSNYKGKSVVLYFYVKDMTPGCTVQSIGIKDSMERIRALGAEVIGISSDDLESHKRFAAKYGLNFPLVSDADNSISKAYGVFNEEKGRARRVTFIIDRDGVIRHIMNRVDVKSHADDVIDMLKKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCH3</accession>
    <name>A0A2H5VCH3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aconitate hydratase A</fullName>
            <ecNumber evidence="8">4.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acnA</name>
        <name evidence="8" type="ORF">HRbin05_00306</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="8"/>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74271">
        <property type="protein sequence ID" value="GBC74271"/>
        <property type="gene ID" value="HRbin05_00306"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01580">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044137">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01341">
        <property type="entry name" value="aconitase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="6">
        <location>
            <begin position="62"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="7">
        <location>
            <begin position="662"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="866" mass="95971" checksum="6D74E246EF80D1E4" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCI9</accession>
    <name>A0A2H5VCI9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ZnF_CDGSH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00453</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74413">
        <property type="protein sequence ID" value="GBC74413"/>
        <property type="gene ID" value="HRbin05_00453"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZnF_CDGSH" evidence="3">
        <location>
            <begin position="11"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="57" mass="6170" checksum="6F90D9A08EEFF9DF" modified="2018-02-28" version="1">MAKIRIYAVENGPYVVELDGKTHSALCRCGASNNKPYCDGSHRRVGFNASASNIVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCJ0</accession>
    <name>A0A2H5VCJ0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-directed RNA polymerase subunit beta</fullName>
            <ecNumber evidence="3">2.7.7.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpoC</name>
        <name evidence="3" type="ORF">HRbin05_00420</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74380">
        <property type="protein sequence ID" value="GBC74380"/>
        <property type="gene ID" value="HRbin05_00420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb1_5" evidence="2">
        <location>
            <begin position="2"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="125" mass="12922" checksum="1A97BB9F0C3C3586" modified="2018-02-28" version="1">MLGIEAARTALVKEIMNTLEEQGLEVDIRHIMLVADVMTSKGMLQQIGRHGVAGTKTSVLARAAFEITVPTIAEAALKGEIEPLKGVTENVIVGSTVPVGTGMVDLYMKVGNGSASVASSDAEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCJ5</accession>
    <name>A0A2H5VCJ5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00456</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74416">
        <property type="protein sequence ID" value="GBC74416"/>
        <property type="gene ID" value="HRbin05_00456"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="349" mass="39283" checksum="B5080CCBF66D101B" modified="2018-02-28" version="1">MMNALPVRLDEQIKDVLRSAAVRSDVTWAIVRDGAVAEFSLGSLNDVSISMDRISAENEHGAMSLDMGSNGNMYAIVAESAEYRCTPWTQCIYLCMYRDEARMNSRGVLTYVGKYDDYCCSSMWDMGIGDDTLDVYIIVKDDNLNSILREMEGKNILKEQSILDNIVKASPYRLFMTKKASILVKQRIGSVDGAHTHLMPDVILNGIRYPTPVPEQMSCIVQVDPFASLIDCNGNYRAWSVEDDPFQMLLQKYNKGYAEEKQRLRDNVLDMLMRGSYYADHVELMYKRADANSKDMLRVVLAQIACDSRVEQTIRMSSVKILTRVGAVNLPAVISCIRTNGSSPLSIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCK2</accession>
    <name>A0A2H5VCK2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VWFA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000017">
        <property type="protein sequence ID" value="GBC74418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74418">
        <property type="protein sequence ID" value="GBC74418"/>
        <property type="gene ID" value="HRbin05_00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="87"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="259" mass="29139" checksum="4295C1BC0A53B9FB" modified="2018-02-28" version="1">MVKRMSAIAGKREEVSIAKALDVPELADDYAQYDPDLVNRLKRMLRDWKRGMVELYASAGDELDTEMLTVHANKPFISEQDRKIKGRLLLLLDHSSSISSDEQEYKRVFTALCKVLDYLGVNFIALAFNTTRGKARCWVIKGEGEHWSKSCERRMQAVKASGGTPLAEVYEKIEPLTRAFKPDIFMTFSDGEPNDPAATREAIKRFKRMGIDMVSFGISNNTARALSIAQNLKDLGYDRCVAVSRLNEIPKKVLALLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCQ0</accession>
    <name>A0A2H5VCQ0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Minor extracellular protease vpr</fullName>
            <ecNumber evidence="8">3.4.21.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">vpr</name>
        <name evidence="8" type="ORF">HRbin05_00510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.-" evidence="8"/>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74469">
        <property type="protein sequence ID" value="GBC74469"/>
        <property type="gene ID" value="HRbin05_00510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="533"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="6">
        <location>
            <begin position="1"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="7">
        <location>
            <begin position="91"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="620"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="623"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="662" mass="70675" checksum="88E71294FB45553D" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCQ1</accession>
    <name>A0A2H5VCQ1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 19">Adenosylcobinamide-GDP ribazoletransferase</fullName>
            <ecNumber evidence="7 19">2.7.8.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 19">Cobalamin synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 19">Cobalamin-5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19 20" type="primary">cobS</name>
        <name evidence="20" type="ORF">HRbin05_00517</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="16 19">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 19">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="19">Cell membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 19">Belongs to the CobS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="7 19"/>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74476">
        <property type="protein sequence ID" value="GBC74476"/>
        <property type="gene ID" value="HRbin05_00517"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00719">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003805">
        <property type="entry name" value="CobS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34148">
        <property type="entry name" value="PTHR34148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02654">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00317">
        <property type="entry name" value="cobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 19" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 19 20" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="30"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00015850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="GBC74476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="255" mass="26894" checksum="2C3B1355B3ACE3DC" modified="2018-02-28" version="1">MGIIDVLSSLISFLSIIPIPKRKTYDIEYIAGYMFLFPIVGVLIGAIIGIVALLLSLAISNGMIVALLVIAIMLVITGMHHTDALADFADGIMAKGSREDKIKALRDPAIGAAGASILIMYILGLFIALSMLDGLSILRAIVVSECIAKYSMVLQASMGRVAWEGMGAPFVRAMKGKECRGVNWSRLIIATITTVGVAYATLEQIGVYAIIGSTAIAMLLLAIANRNFGGVSGDLFGATNELSRLTSLLVIGGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCQ6</accession>
    <name>A0A2H5VCQ6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsH_1</name>
        <name evidence="5" type="ORF">HRbin05_00391</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. CDC48 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74351">
        <property type="protein sequence ID" value="GBC74351"/>
        <property type="gene ID" value="HRbin05_00391"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005938">
        <property type="entry name" value="AAA_ATPase_CDC48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003338">
        <property type="entry name" value="CDC4_N-term_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02359">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01073">
        <property type="entry name" value="CDC48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="SSF54585"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01243">
        <property type="entry name" value="CDC48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48_N" evidence="4">
        <location>
            <begin position="9"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="CDC48_2" evidence="3">
        <location>
            <begin position="107"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="211"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="484"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="722" mass="80268" checksum="652C9CF3D2143DEC" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCQ7</accession>
    <name>A0A2H5VCQ7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA base-flipping protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">atl</name>
        <name evidence="8" type="ORF">HRbin05_00505</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74464">
        <property type="protein sequence ID" value="GBC74464"/>
        <property type="gene ID" value="HRbin05_00505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="7">
        <location>
            <begin position="11"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="111" mass="12659" checksum="F350F15D8A3F8C92" modified="2018-02-28" version="1">MNMSMDEMSIMVYRLVSMVPEGRVCTYSDLARALGKPKAYRLVGKILNRNPNPVVVPCHRVVRSDGRVGGYMHGYEAKRRLLEGEGIRIDGKGMIVDFDSVRFRLDKINER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCQ9</accession>
    <name>A0A2H5VCQ9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GMP synthase (glutamine-hydrolyzing)</fullName>
            <ecNumber evidence="4">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">GMP synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">guaA</name>
        <name evidence="13" type="ORF">HRbin05_00523</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74482">
        <property type="protein sequence ID" value="GBC74482"/>
        <property type="gene ID" value="HRbin05_00523"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 11" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="12">
        <location>
            <begin position="78"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="106"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GBC74482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="395" mass="44096" checksum="0F4B9E8E3698784D" modified="2018-02-28" version="1">MGIKQRMRCWMSHGDAAESLPEGFSILAHTESSFAAAVADRARKVYGLQFHPEVAHTEHGSDILRNFAVRICNARQEWSMSNFIDNAVNDIRSKVKEGERVLAAVSGGIDSTVTALLVHRAVGDRLTCIFINHGLLREGEEDEVLDMFKTLGIKPIYIDASSRFLTRLKDVEDPEVKRLIIGEEFARVFDDAVKEHGPFHWLAQGTLYPDVIESGVSISREAATIKSHHNVAGLPKWLNLKVLEPLRQLYKDEVRQVARLLGVPEHMVKRHPFPGPGLAVRIIGKVTEEKLRICKRASRIVEEELARAGLYDKVWQAFAIVGDDRAVGVLGDGRVYGHIVSIRVVESVDAMTADWAKLPYELLARISNRITNEVEGVTWVTYAISSKPPATIEPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCR0</accession>
    <name>A0A2H5VCR0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L44e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpl44e</name>
        <name evidence="4" type="ORF">HRbin05_00520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the eukaryotic ribosomal protein eL42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000021">
        <property type="protein sequence ID" value="GBC74479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74479">
        <property type="protein sequence ID" value="GBC74479"/>
        <property type="gene ID" value="HRbin05_00520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01476">
        <property type="entry name" value="Ribosomal_L44e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000552">
        <property type="entry name" value="Ribosomal_L44e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10369">
        <property type="entry name" value="PTHR10369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00935">
        <property type="entry name" value="Ribosomal_L44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01172">
        <property type="entry name" value="RIBOSOMAL_L44E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="zinc finger region" description="C4-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="92" mass="10805" checksum="6EDBD604F5F75EB4" modified="2018-02-28" version="1">MKVPKEINTYCPRCKKHTVHTISLYKKGKERGTAWGVRRHEEEKKGYGGQKYPEQKRTAKTTKKQLLKFKCKDCGYTLQRHGIRLRKVEIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCS5</accession>
    <name>A0A2H5VCS5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cysteine synthase B</fullName>
            <ecNumber evidence="2">2.5.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">cysM</name>
        <name evidence="2" type="ORF">HRbin05_00536</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74495">
        <property type="protein sequence ID" value="GBC74495"/>
        <property type="gene ID" value="HRbin05_00536"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="1">
        <location>
            <begin position="23"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="367" mass="41128" checksum="6051DA6C0982501B" modified="2018-02-28" version="1">MSEREEGRRRDKMKALTPELLNKIGNTPLIELRSFSSSRVRVLAKLEWFNPFGSVKDRAAYWMFKDAEGKGLIARGKHVIIEPTSGNTGIALAGIARLLGYEVEIVIPEKVSKETKDILRALGANLYETSDDLCPRVGVGTDQSISLAKAIARARPDKYYMPNQYENDANFLAHYEGTGPEIWAQTNGKVTHFVAGVGTGGTITGVGLYLKERNKAIRVIAVQPQKQHLIQGLRNFEESNIPTLFERRANVVDEWHTITNEESFKMVRELYERERLLVGPSSGCAMAAVCKVKERIESSLDRVEEDYDGDDGNRNGNGNGRRENIIVVVFADNGRKFRSLYSQQGVFSNEEFDDALRNAIMLGESFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCS8</accession>
    <name>A0A2H5VCS8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase</fullName>
            <shortName evidence="2">ADH synthase</shortName>
            <shortName evidence="2">ADHS</shortName>
            <shortName evidence="2">ADTH synthase</shortName>
            <ecNumber evidence="2">2.2.1.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">griI</name>
        <name evidence="2" type="synonym">aroA'</name>
        <name evidence="3" type="ORF">HRbin05_00540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes a transaldol reaction between 6-deoxy-5-ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-deoxy-D-threo-hexo-2,5-diulose 6-phosphate + L-aspartate 4-semialdehyde = 2,3-dioxopropyl phosphate + 2-amino-2,3,7-trideoxy-D-lyxo-hept-6-ulosonate</text>
            <dbReference type="Rhea" id="RHEA:25952"/>
            <dbReference type="ChEBI" id="CHEBI:58859"/>
            <dbReference type="ChEBI" id="CHEBI:58860"/>
            <dbReference type="ChEBI" id="CHEBI:58861"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="2.2.1.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DeoC/FbaB aldolase family. ADHS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.10" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74499">
        <property type="protein sequence ID" value="GBC74499"/>
        <property type="gene ID" value="HRbin05_00540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016744">
        <property type="term" value="F:transketolase or transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00958">
        <property type="entry name" value="DhnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00960">
        <property type="entry name" value="ADH_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010210">
        <property type="entry name" value="ADH_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041720">
        <property type="entry name" value="FbaB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038992">
        <property type="entry name" value="Aldolase_Ia"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01949">
        <property type="entry name" value="AroFGH_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0704">Schiff base</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="DKFP binding" evidence="2">
        <location>
            <begin position="24"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="DKFP binding" evidence="2">
        <location>
            <begin position="142"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="DKFP binding" evidence="2">
        <location>
            <begin position="198"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="DKFP binding" evidence="2">
        <location>
            <begin position="226"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="2">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="261" mass="27963" checksum="6FAC0BA545059558" modified="2018-02-28" version="1">MVTGREIRLSRILRDGKMLCIPMDHGISSGPIAGIDDIHSMIYRCEDSGLTSVLINKGILRSMPRPSKVGIIVHLSGSTSLGPAPNRKVLMGSVEDAVRLGADGVSVHINIGSKEEPEMLIKLGHVASECIEWNMPLIAMMYPRGENIKNPHDPDVVAHTARVGAEAGADIVKTVYTGDPDSFRRVVKGCPVPIVIAGGPKTSNDEEVLEMTKGAMEAGAVGVTFGRNIFQHRDPPAMIRALASIIFENASVKEALKEIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCT2</accession>
    <name>A0A2H5VCT2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00538</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74497">
        <property type="protein sequence ID" value="GBC74497"/>
        <property type="gene ID" value="HRbin05_00538"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="36" mass="4048" checksum="C2BBE14B61D410C4" modified="2018-02-28" version="1">MIAKVTIPLRLCVDAGYGKVNMVNVKYDIVMVNIHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCU2</accession>
    <name>A0A2H5VCU2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal_L7Ae domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00421</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74381">
        <property type="protein sequence ID" value="GBC74381"/>
        <property type="gene ID" value="HRbin05_00421"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004038">
        <property type="entry name" value="Ribosomal_L7Ae/L30e/S12e/Gad45"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01248">
        <property type="entry name" value="Ribosomal_L7Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L7Ae" evidence="2">
        <location>
            <begin position="6"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="104" mass="11477" checksum="684B42B441B5DF5C" modified="2018-02-28" version="1">MSKLIAKIVRNAMASNSCRIGSREVLKDISNAKLIICSRSVSRDVVERLRSNGNSSAYIYNIDKNSMELGRLCGKPFRISIISVMDVSKEDLDALIAEANTQGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCV6</accession>
    <name>A0A2H5VCV6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74536">
        <property type="protein sequence ID" value="GBC74536"/>
        <property type="gene ID" value="HRbin05_00578"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="279" mass="31345" checksum="45EC62C27F94AF6B" modified="2018-02-28" version="1">MHFEKLIEPDLKGKSPIMIAAMQDMGNVGSIVIDFINKALKTSPFRVVYAHYPPYVVDKGGYIEFEQIRWEYRYAERIIVFGGSLGQPESSSDLYLLCQDVIDVAKMYSVQFIYTVGAFLTDKEVGKNPRVLVTTTNPMLTDSIVKVGLYPTHGSSLITGFNGLILGFAKMNNIHGIGLYGEIDDPRIPQYRTAKSIIQALERLTYLKFDNLDELDRFAEGVEESIARRKESKGKDEKRGRSEGRERERGRGGGEEEEGEGGAIDSDGDNDDEVDEYLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCW4</accession>
    <name>A0A2H5VCW4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HRbin05_00570</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the C-terminal section; belongs to the transposase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74528">
        <property type="protein sequence ID" value="GBC74528"/>
        <property type="gene ID" value="HRbin05_00570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001959">
        <property type="entry name" value="Transposase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Transposase_IS605_OrfB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01385">
        <property type="entry name" value="OrfB_IS605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="OrfB_Zn_ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01766">
        <property type="entry name" value="tspaseT_teng_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="OrfB_IS605" evidence="5">
        <location>
            <begin position="183"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="OrfB_Zn_ribbon" evidence="6">
        <location>
            <begin position="314"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="446" mass="52649" checksum="1355AFE66986EC0C" modified="2018-02-28" version="1">MQRANIFIVEDNRSLKELADNCSRLYNELNYERRQSYIHCKRFEWYPKHLYKKYASMIGSATAQQIIKKNNEAWRSFLALKRLEREGKLPKHISRISMPRYWKLKGRRELRVIVRNDCYRIDDDEEYIYLPKGLKLKYKGKLRYKGNQGRLEILYDTIDKVWRGFMSVKVEKHLLRGGSNSNDNNNNNDKPLYIDLGVVNLATVWFNGLRQPIAYSGRAILADWWYLSNRIAREQSRVAKVNNKAKTSRSISRLYRIRQRRFRHSINAMVKKIVEDAYMLGISRIVIGDIKGIRSNHTSNNSKANSMINNFWSFNYILRRFKDKAEEYGIKVEEVSEYNTSSICPFCKSNGIRKHRGLFYCPTCNKAMNADVVGVLNIANRDNNSKDGSKTNQIHIIPSSWRSSRSRDNRLVAQPLLLRWDGMKWDTKRYMNNRLMNTLEARISRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCY5</accession>
    <name>A0A2H5VCY5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00608</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000029">
        <property type="protein sequence ID" value="GBC74566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74566">
        <property type="protein sequence ID" value="GBC74566"/>
        <property type="gene ID" value="HRbin05_00608"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="120" mass="13022" checksum="14850338188186A8" modified="2018-02-28" version="1">MMNNNNNIEDKAVSVNRTNLSSKGSNSNSRKRKDASSSSSNTKITNNNNNNSNNNNNNTINLKELSNEELKELAIKKIERIEELLLQILPFTTTTSTTSTATNTANTNTATAITANTSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCY6</accession>
    <name>A0A2H5VCY6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00572</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000026">
        <property type="protein sequence ID" value="GBC74530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74530">
        <property type="protein sequence ID" value="GBC74530"/>
        <property type="gene ID" value="HRbin05_00572"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006980">
        <property type="entry name" value="NH3_CH4_mOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023349">
        <property type="entry name" value="NH3_CH4_mOase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04896">
        <property type="entry name" value="AmoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="187" mass="21207" checksum="D112CDF18798859C" modified="2018-02-28" version="1">MAQMPALLPKEVEMQRLKKILIMVIVMGSVAASVEVDNFVDGSLHQTSIRDSAFTPAHWWLYSHFVALPLGWGAIMIYDRRVPLMRGPNNSVNTGIKMTIIGYLGTMFTIGINEMWHFWFVEEVFAVPNHWSFNMGVVVAFMGALAYVVRLYVRMVELGMETPPSNPYVAEMYKLALEGKLYSRSIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCY7</accession>
    <name>A0A2H5VCY7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="7">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">valS</name>
        <name evidence="7" type="synonym">leuS</name>
        <name evidence="12" type="ORF">HRbin05_00605</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="7"/>
    <dbReference type="EMBL" id="BEHH01000029">
        <property type="protein sequence ID" value="GBC74563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74563">
        <property type="protein sequence ID" value="GBC74563"/>
        <property type="gene ID" value="HRbin05_00605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_A">
        <property type="entry name" value="Leu_tRNA_synth_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020791">
        <property type="entry name" value="Leu-tRNA-lgase_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004493">
        <property type="entry name" value="Leu-tRNA-synth_Ia_arc/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45794">
        <property type="entry name" value="PTHR45794"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00395">
        <property type="entry name" value="leuS_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="12"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1g" evidence="11">
        <location>
            <begin position="608"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="10">
        <location>
            <begin position="755"/>
            <end position="889"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="648"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="651"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="GBC74563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="1023" mass="117643" checksum="D293E8BE86772696" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCZ3</accession>
    <name>A0A2H5VCZ3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="3">6.1.1.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">alaS_1</name>
        <name evidence="3" type="ORF">HRbin05_00604</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000029">
        <property type="protein sequence ID" value="GBC74562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74562">
        <property type="protein sequence ID" value="GBC74562"/>
        <property type="gene ID" value="HRbin05_00604"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="520" mass="58342" checksum="411B1566011248AF" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCZ8</accession>
    <name>A0A2H5VCZ8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00614</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74572">
        <property type="protein sequence ID" value="GBC74572"/>
        <property type="gene ID" value="HRbin05_00614"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="67" mass="7189" checksum="97536E9385560945" modified="2018-02-28" version="1">MFKLNMAVKYKMGYVALGILTVAILLASNYVYATADVVLNVGQTKPVSLGKDVEPGSVKSSDPEILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCZ9</accession>
    <name>A0A2H5VCZ9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00611</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74569">
        <property type="protein sequence ID" value="GBC74569"/>
        <property type="gene ID" value="HRbin05_00611"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="68" mass="7483" checksum="52DA66E3E838C339" modified="2018-02-28" version="1">MIVASKSNRVLRIGSTVRARITAVSLKGGAMGKIGVTCRQPFLGAEEWIREDVKKAEQQRAKVEEAKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD27</accession>
    <name>A0A2H5VD27_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Transcription elongation factor Spt5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nusG</name>
        <name evidence="3" type="synonym">spt5</name>
        <name evidence="6" type="ORF">HRbin05_00502</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Stimulates transcription elongation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the SPT5 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal Spt5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74461">
        <property type="protein sequence ID" value="GBC74461"/>
        <property type="gene ID" value="HRbin05_00502"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00950">
        <property type="entry name" value="Spt5_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005100">
        <property type="entry name" value="NGN-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011590">
        <property type="entry name" value="Spt5_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03439">
        <property type="entry name" value="Spt5-NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00405">
        <property type="entry name" value="KOW_elon_Spt5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NGN" evidence="4">
        <location>
            <begin position="3"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="156" mass="17395" checksum="5D7B78A3EE978EF4" modified="2018-02-28" version="1">MPESKFFIIRTTGGQEHTVARLIENRIAIKNIGILSVLVLDNMKGYIIIEAMDGNALIEALSGLKHVRGQLKGEMDFKDIEGMLIKKPAVSELAVDDVVEIIGGPFKGMKARITRVDYDKQEARVVLLDAQYQLPVTIDTNYLKLLQKASQQQKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD30</accession>
    <name>A0A2H5VD30_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00622</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74580">
        <property type="protein sequence ID" value="GBC74580"/>
        <property type="gene ID" value="HRbin05_00622"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="247" mass="28432" checksum="197994A7DABA5E76" modified="2018-02-28" version="1">MKKLEIVLSRDSLHHVVERLALIEHIKSLHVTSSELVNLHTKEEDARSLISIKIEFVVEDEYVDEVLQLLLGDDKITFGRIYVLAVDRAFELGYREGYRFRLALSSLIRASRKDVFNIVTDYEHLAELFPSYFKSISIRSSSDNMTVTEEEITIDNLSIKQISRHIVYPPAVHEVEILSGYLEGSRITETYTEASEGTQVMVIADIKIKEPLARVFGFHIRHKVEQQIKGVMKELARFVEDRLDAVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD34</accession>
    <name>A0A2H5VD34_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Fumarate reductase flavoprotein subunit</fullName>
            <ecNumber evidence="11">1.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">frdA</name>
        <name evidence="11" type="ORF">HRbin05_00651</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.4" evidence="11"/>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74607">
        <property type="protein sequence ID" value="GBC74607"/>
        <property type="gene ID" value="HRbin05_00651"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102040">
        <property type="term" value="F:fumarate reductase (menaquinone)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003952">
        <property type="entry name" value="FRD_SDH_FAD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014006">
        <property type="entry name" value="Succ_Dhase_FrdA_Gneg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01812">
        <property type="entry name" value="sdhA_frdA_Gneg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00504">
        <property type="entry name" value="FRD_SDH_FAD_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="9">
        <location>
            <begin position="11"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="10">
        <location>
            <begin position="454"/>
            <end position="578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="578" mass="64675" checksum="02F39E3130162AD9" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD49</accession>
    <name>A0A2H5VD49_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HRbin05_00652</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74608">
        <property type="protein sequence ID" value="GBC74608"/>
        <property type="gene ID" value="HRbin05_00652"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000701">
        <property type="entry name" value="SuccDH_FuR_B_TM-su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01127">
        <property type="entry name" value="Sdh_cyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="142" mass="15769" checksum="89EF35ECC0961689" modified="2018-02-28" version="1">MKENREGIKGWLNPTRYGANRFAYWLQRLTGLGLLVYFIAHVIETSNIVYGKNAWEKMLAVTQTTEGHIVLMVVIGMCVFHAANGVRLYIAEHGKGIGRPGRPEYPYKPTSLGLGMKACIWVSVALAALAMMYGAYVLFGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD50</accession>
    <name>A0A2H5VD50_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfurtransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cysA</name>
        <name evidence="3" type="ORF">HRbin05_00644</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74600">
        <property type="protein sequence ID" value="GBC74600"/>
        <property type="gene ID" value="HRbin05_00644"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004792">
        <property type="term" value="F:thiosulfate sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001307">
        <property type="entry name" value="Thiosulphate_STrfase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00683">
        <property type="entry name" value="RHODANESE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="20"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="159"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="280" mass="32361" checksum="5CAF786387D8B2A7" modified="2018-02-28" version="1">MSYAHPEVLVSTQWVHEHLNDPKVRIAEVDYDPTSNYMLGHIPNAVLFDWKKDINDPLRRDILSKEACEDLLQRAGCNSDTILVLYGDFNNWFAAFAFWVFKYYGYEDVRLMNGGRKKWLEEDRPVTKDVPTFARGNWKAKDPDRTIRVFKQYVESILGMKDKVLVDVRSPKEYTGEILAPPEYPTEAAQRGGHIPTAINIPWAQAVNEDGTFKSAEELRRLYESKGITKDKEVITYCRIGERSSHTWFVLKYLLGYPNVKNYDGSWSEWGNAVGLPIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD54</accession>
    <name>A0A2H5VD54_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="6">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Alpha-IPM isomerase</fullName>
            <shortName evidence="6">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dmdA</name>
        <name evidence="6" type="synonym">leuC</name>
        <name evidence="8" type="ORF">HRbin05_00671</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000035">
        <property type="protein sequence ID" value="GBC74627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74627">
        <property type="protein sequence ID" value="GBC74627"/>
        <property type="gene ID" value="HRbin05_00671"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01027">
        <property type="entry name" value="LeuC_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011826">
        <property type="entry name" value="HAcnase/IPMdehydase_lsu_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006251">
        <property type="entry name" value="Homoacnase/IPMdehydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01343">
        <property type="entry name" value="hacA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02086">
        <property type="entry name" value="IPMI_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="5 6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="7">
        <location>
            <begin position="8"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="428" mass="46926" checksum="8CBE40DD6E990DEE" modified="2018-02-28" version="1">MCGMTITEKILARASNRERVTAGDVVFASVDKVMVHDVSGPGVMMVLRELERKGKRVERVWDPDRVWIAEDHFVPAVDKIAAENIITLERMSERFGIKKHFRYGLGQYGICHTLSHEEAMVLPGEVYVGGDSHTNTTGALGCFATGMGHTDIAYVLIHGKIWFRVPETLLFRLEGHIPPYIMAKDIILKIIGDSGTDVANYKAMQFAGSAVAEMPMDERFTLTNMTTEAGAKNGIIEPDEKTIAYVKERTDRPFKVLKGDDDAEYEEVFTYEVDKLEPIVAKPYSPANIAYARELNSVEIDRAYIGSCTGAKYTDLLEAARILKGRKAKVRLEVLPASQSIYMKALNDGLLSIFLEAGAVIGPPTCGACCGAHMGVLAKDEVCVSTTNRNFPGRMGHVESKTYLASPKVVAASAVTGRITDPRDVVDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD55</accession>
    <name>A0A2H5VD55_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">30S ribosomal protein S5</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsE</name>
        <name evidence="7" type="ORF">HRbin05_00666</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74622">
        <property type="protein sequence ID" value="GBC74622"/>
        <property type="gene ID" value="HRbin05_00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005711">
        <property type="entry name" value="Ribosomal_S5_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01020">
        <property type="entry name" value="uS5_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="6">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="147" mass="15636" checksum="77E289B9E8DDEFED" modified="2018-02-28" version="1">MHVGVVQKQTDAGELTRFSAIVACGDEHGWFGIGRGKAAQMRLAIDKATRDAMLNIIPVKLGCGSWECRCNVQHSVPFKVVGKGGSVKIEIIPGPRGLGLVAGANITMMLRLAGIRDAWTRTFGSTSTMSSTALAVYNALRNTYSIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD56</accession>
    <name>A0A2H5VD56_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplO</name>
        <name evidence="4" type="synonym">rpl15</name>
        <name evidence="7" type="ORF">HRbin05_00663</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74619">
        <property type="protein sequence ID" value="GBC74619"/>
        <property type="gene ID" value="HRbin05_00663"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027386">
        <property type="entry name" value="Rbsml_prot_L15/27a_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="6">
        <location>
            <begin position="16"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="142" mass="15853" checksum="11E91455206DF1C8" modified="2018-02-28" version="1">MATRRRKVRRLRGSRTHGWGQIGQHRDTGKKGYRKVGLHKHKWTQAVLMEGKYFGKHGFHNPTSRSIERWVNVGSLDDLFLKYGKVDGDNNDGKKVIDLNSLGYDKLLGSGNVKGAYSVIVKACTESARNKVISAGGEIILC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD62</accession>
    <name>A0A2H5VD62_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S3Ae</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosomal protein S1e</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rps3ae</name>
        <name evidence="4" type="ORF">HRbin05_00678</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the eukaryotic ribosomal protein eS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000036">
        <property type="protein sequence ID" value="GBC74634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74634">
        <property type="protein sequence ID" value="GBC74634"/>
        <property type="gene ID" value="HRbin05_00678"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00359">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030838">
        <property type="entry name" value="30S_S3Ae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001593">
        <property type="entry name" value="Ribosomal_S3Ae"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01015">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01397">
        <property type="entry name" value="Ribosomal_S3Ae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="212" mass="24719" checksum="E3ABCC38796BBD87" modified="2018-02-28" version="1">MPTKKGGKVRDKWRDKRWVVVHAPSVFANQPIAYIPITDEKHAIGRVIECTLFDLWHTDPQQHAIKLYFQIERIEGDDAYTYLKGHEYTKEFIKSMVRRGSSMVNFIKDYTTADGYTFRIYTIAFTQKKVNTSKKHDIRKVMDEVLSREVPMLNIDQFIQAVVGPKLNADIHSRVKDIINVRFVAVWKTKLLGKKQPIIQVQQEQQAQTLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD72</accession>
    <name>A0A2H5VD72_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00664</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74620">
        <property type="protein sequence ID" value="GBC74620"/>
        <property type="gene ID" value="HRbin05_00664"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="46" mass="5146" checksum="B4B0B6A9892D9AAC" modified="2018-02-28" version="1">MISQREGAYTRWRFLAYEHGVYKALAKSDIEFVVVAGTSIVAVNVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD74</accession>
    <name>A0A2H5VD74_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase</fullName>
            <ecNumber evidence="3">6.3.4.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate--formate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purP</name>
        <name evidence="6" type="ORF">HRbin05_00686</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + ATP + formate = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24836"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (formate route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.23" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000037">
        <property type="protein sequence ID" value="GBC74642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74642">
        <property type="protein sequence ID" value="GBC74642"/>
        <property type="gene ID" value="HRbin05_00686"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00134"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01163">
        <property type="entry name" value="IMP_biosynth_PurP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023656">
        <property type="entry name" value="IMP_biosynth_PurP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009720">
        <property type="entry name" value="IMP_biosynth_PurP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010672">
        <property type="entry name" value="IMP_biosynth_PurP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38147">
        <property type="entry name" value="PTHR38147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06849">
        <property type="entry name" value="DUF1246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06973">
        <property type="entry name" value="DUF1297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004602">
        <property type="entry name" value="ATPgrasp_PurP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="114"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</name>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</name>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</name>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="353" mass="40387" checksum="82D9573D0CAB0C49" modified="2018-02-28" version="1">MMNAIGTLGSHCALQVLRGAKDEGFKTILVCERRREGLYRRFRFIDRLLLVEDYRFEHSFSESVQNELHDNNCILVPHGTYISSMSIEEIESIRIPFFGNRWILRWEADRALKERLMLEARLNVPKSISIDELNGSSDGSKEARLVIAKLHGAAGGKGYFLAWDRESFMTQYNKLLSKGMVKSIDDLYIQEYVLGVPVYLQYFYSPLNREVELLGIDRRYESNVDAIGRIPALQQESSGVHEVSYNVIGNSPLVLRESLLDEVYRMGERFVSAAERLVKRGMIGPFCIEGVYDQDGRFIAFEFSARIVAGTNLYVNGSPYSYLLYDEPMSMGRRIAREVRIAIDSNELDKVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD77</accession>
    <name>A0A2H5VD77_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00687</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000037">
        <property type="protein sequence ID" value="GBC74643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74643">
        <property type="protein sequence ID" value="GBC74643"/>
        <property type="gene ID" value="HRbin05_00687"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="52" mass="6339" checksum="FC7C1D70590707C5" modified="2018-02-28" version="1">MHEMKDEDVYTYWGIRKEYERLARIERLAKLLLLLPFASTILILIMVFLLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD82</accession>
    <name>A0A2H5VD82_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S8e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rps8e</name>
        <name evidence="6" type="ORF">HRbin05_00701</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the eukaryotic ribosomal protein eS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74656">
        <property type="protein sequence ID" value="GBC74656"/>
        <property type="gene ID" value="HRbin05_00701"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00029">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020919">
        <property type="entry name" value="Ribosomal_protein_S8e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001047">
        <property type="entry name" value="Ribosomal_S8e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022309">
        <property type="entry name" value="Ribosomal_S8e/biogenesis_NSA2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10394">
        <property type="entry name" value="PTHR10394"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01201">
        <property type="entry name" value="Ribosomal_S8e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00307">
        <property type="entry name" value="eS8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="126" mass="14108" checksum="3114E35837B50F39" modified="2018-02-28" version="1">MKKSVENLLKRKPTGGKRKAYRGRRKYEIDRYPIETLLGKEERIVKRVRGGNIKVACKSVEYANVVDSKEGKVVKAKILRVVRNIADKDYDRRGVITKGAVIETEAGTARVVSRPGQDGVVNAVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDA1</accession>
    <name>A0A2H5VDA1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Macrolide export ATP-binding/permease protein MacB</fullName>
            <ecNumber evidence="9">3.6.3.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">macB</name>
        <name evidence="9" type="ORF">HRbin05_00719</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.-" evidence="9"/>
    <dbReference type="EMBL" id="BEHH01000041">
        <property type="protein sequence ID" value="GBC74674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74674">
        <property type="protein sequence ID" value="GBC74674"/>
        <property type="gene ID" value="HRbin05_00719"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="21"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="310"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="414" mass="44272" checksum="57907504390E9023" modified="2018-02-28" version="1">MDIIKITQLAFDALRERKVRSILTILMVTTGTSLLIAVNGLTTGFLVFADKQFSMLAPNVIFVSPAPTQSSGLGGGPPQAPKIVLTSVVVDRIKNLPAVSDVIPNYTGVVSIESRGKVQNARVFAQDITKIYSIAPGIEFEEGSILSNNQSSIVISERIARPPGDSIPFATIGQTVVVKYSYVDEDGERKTNSRTFVVRGIFKLTGNPTIDGAAIIHPDVANMLMNKKGRYDGIVVLARNSDLVEDVEDGIRRLYGNDVGITSSKVILTTIRQFIGGITTFLFSIAVISLIVGAIGIITTLYTSVLERTREIGILKAIGAQNRHILLLFLMEALIIGSIGAVVGIPLGMAGGDLLSNLAPGNREAPPDARSRPLYTVEDITRVCALSIGLSVVSGLYPSFRASRLDPIVALGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDA6</accession>
    <name>A0A2H5VDA6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74650">
        <property type="protein sequence ID" value="GBC74650"/>
        <property type="gene ID" value="HRbin05_00695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="63" mass="7251" checksum="E3502E9D67152EE8" modified="2018-02-28" version="1">MHASSGYRWFYHTLMHVMTLTAFARIDGVLEGTPFASEIDQTRNSWNDLPSIFEIRRSTGCNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDB5</accession>
    <name>A0A2H5VDB5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="3">3.4.24.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ftsH_2</name>
        <name evidence="3" type="ORF">HRbin05_00730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000043">
        <property type="protein sequence ID" value="GBC74684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74684">
        <property type="protein sequence ID" value="GBC74684"/>
        <property type="gene ID" value="HRbin05_00730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005938">
        <property type="entry name" value="AAA_ATPase_CDC48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004201">
        <property type="entry name" value="Cdc48_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029067">
        <property type="entry name" value="CDC48_domain_2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02933">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01072">
        <property type="entry name" value="CDC48_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54585">
        <property type="entry name" value="SSF54585"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01243">
        <property type="entry name" value="CDC48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CDC48_2" evidence="2">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="110"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="383"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="622" mass="69652" checksum="EDE2FD8B094FFD52" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDB6</accession>
    <name>A0A2H5VDB6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase</fullName>
            <ecNumber evidence="6">1.1.1.302</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ribD2</name>
        <name evidence="11" type="ORF">HRbin05_00705</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NAD(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:27274"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2,5-diamino-6-(1-D-ribitylamino)pyrimidin-4(3H)-one 5'-phosphate + NADP(+) = 2,5-diamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:27278"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58890"/>
            <dbReference type="ChEBI" id="CHEBI:59545"/>
            <dbReference type="EC" id="1.1.1.302"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; riboflavin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HTP reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.302" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000039">
        <property type="protein sequence ID" value="GBC74660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74660">
        <property type="protein sequence ID" value="GBC74660"/>
        <property type="gene ID" value="HRbin05_00705"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006401">
        <property type="entry name" value="Rib_reduct_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011549">
        <property type="entry name" value="RibD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01508">
        <property type="entry name" value="rib_reduct_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00227">
        <property type="entry name" value="ribD_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="10">
        <location>
            <begin position="8"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00015035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="229" mass="25224" checksum="ED0B59746B230AAD" modified="2018-02-28" version="1">MKAHMDRPYVIINAAMSVDGKISSVGNDSRLSSKHDLVRVHRLRSMVDAVMVGINTVLIDDPMLNVRYVEGREGSNPSRVVVDSHARISPTSKIMSTCKSIPTIIAVSEHADQARVERLRGMGATVIVVGRDRVDLRMLLKWLRGMGIGKVLVEGGGELNWSLLKEGLVDELMVTVVPVVIGGRDAKTLVEGEGFLRVEEGRRLMLIDVNRMHGNGEVILHYKVLNSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDD9</accession>
    <name>A0A2H5VDD9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Nicotinate-nucleotide pyrophosphorylase [carboxylating]</fullName>
            <ecNumber evidence="6">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">nadC</name>
        <name evidence="9" type="ORF">HRbin05_00613</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>CO2 + diphosphate + nicotinate beta-D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate</text>
            <dbReference type="Rhea" id="RHEA:12733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29959"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Hexamer formed by 3 homodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the NadC/ModD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74571">
        <property type="protein sequence ID" value="GBC74571"/>
        <property type="gene ID" value="HRbin05_00613"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="8">
        <location>
            <begin position="22"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="7">
        <location>
            <begin position="109"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="284" mass="31044" checksum="645440D4578C6E53" modified="2018-02-28" version="1">MKGGKMDSNLLTKLRGFIEEDVGTGDVTSIIVDDRVVEAEIVCKEHAVIAGVEEAVALFNLVNCNAETMVRDGNVVEPDTVIMHIHGNARAVLAVERTVLNLLMRMSGIATCTRKYVEIVKSVNPNVKIASTRKTAPGLRLLDKKAVALGGGYMHRLGLYDMVLIKDNHLALVGSVAKAVRLAREMYGSRYRIEVEVRSLKEALEAIESGADMIMLDNLAVDDVAKIVDELKGRGLRDKVMIEVSGGINEDNIRSYARLDVDMISIGRITHSAKAIDMSLEIVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDI6</accession>
    <name>A0A2H5VDI6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal_L30 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74621">
        <property type="protein sequence ID" value="GBC74621"/>
        <property type="gene ID" value="HRbin05_00665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01657">
        <property type="entry name" value="Ribosomal_L7_archeal_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039699">
        <property type="entry name" value="Ribosomal_L7/L30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035808">
        <property type="entry name" value="Ribosomal_L7_euk_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11524">
        <property type="entry name" value="PTHR11524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribosomal_L30" evidence="2">
        <location>
            <begin position="3"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="144" mass="16454" checksum="B6AF6EFF9469BAB1" modified="2018-02-28" version="1">MAYLVIRLRGTINVPYWARHTLALLNLRRRFNATIVPEQEPYLGMLRKVKDHVAWCKVDAGFVKQLLEKRGRYEDINKLGFSSIDELADALASDKVILSRLNVRPWFALAPPKGGFKKSSKHMYSDGGILGENRELLELASRMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDL3</accession>
    <name>A0A2H5VDL3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Vegetative protein 296</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">sufC</name>
        <name evidence="5" type="ORF">HRbin05_00696</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74651">
        <property type="protein sequence ID" value="GBC74651"/>
        <property type="gene ID" value="HRbin05_00696"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="257" mass="28999" checksum="C817755E86E9D27F" modified="2018-02-28" version="1">MRLEIVDLHVSIDSREIIRGLNLAVESGEVHAIMGPNGSGKSTLAYTLLGHPRYTVSRGDIRLDGESILDLSTDERARKGLFLGFQYPVEISGVSFSNFLRNAYNIMNKSYQDKSREVFLTVREFHDYMKRQIDVVGLDGSFLARYLNEGFSGGEKKRSEVLQMLVLKPRFAILDEPDSGLDIDAVKAVANAINNFISKDTSVMVITHYARILRYLKKLDYVHVMANGRVVRSGGKELAEMLEEKGYGWIEKEVKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBB8</accession>
    <name>A0A2H5VBB8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="5">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">kdkA</name>
        <name evidence="13" type="ORF">HRbin05_00012</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73984">
        <property type="protein sequence ID" value="GBC73984"/>
        <property type="gene ID" value="HRbin05_00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106310">
        <property type="term" value="F:protein serine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05144">
        <property type="entry name" value="RIO2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030484">
        <property type="entry name" value="Rio2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015285">
        <property type="entry name" value="RIO2_wHTH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09202">
        <property type="entry name" value="Rio2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="7 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RIO" evidence="12">
        <location>
            <begin position="64"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GBC73984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="296" mass="33877" checksum="7E539C9AE071C16E" modified="2018-02-28" version="1">MSMLDMARYVKELEDEEVKALKAFARMLREHESVDEEKIAISAKMHVDRVRYALKRLNEKNLIYKSPSKGYHLVYAGLDVLALKELADRGIVASVGRMIGVGKEADVLEAVDDHGRMLAVKFFRIGRVSFRSIARKRMLKDVHSWLLASIETARKEFKSLRRLRVAGASVPEAIALARHAIVMEYIDGVRLVECTSLDDPRHVLEDVLENIRIAYSIGMVSADLSEYNILYDVNGKVWIIDWPQSIDARKHPNAKALLERDLNNIIRFFSKRFGLVYDVNMAIAHVTMHEDDVEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBC5</accession>
    <name>A0A2H5VBC5_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cobalt-precorrin-5B C(1)-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.195</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Cobalt-precorrin-6A synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">cbiD</name>
        <name evidence="7" type="ORF">HRbin05_00011</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Co-precorrin-5B + S-adenosyl-L-methionine = Co-precorrin-6A + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:26285"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:60063"/>
            <dbReference type="ChEBI" id="CHEBI:60064"/>
            <dbReference type="EC" id="2.1.1.195"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 6/10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the CbiD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.195" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73983">
        <property type="protein sequence ID" value="GBC73983"/>
        <property type="gene ID" value="HRbin05_00011"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00227"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043780">
        <property type="term" value="F:cobalt-precorrin-5B C1-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046140">
        <property type="term" value="P:corrin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00787">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002748">
        <property type="entry name" value="CbiD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036074">
        <property type="entry name" value="CbiD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35863">
        <property type="entry name" value="PTHR35863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01888">
        <property type="entry name" value="CbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111342">
        <property type="entry name" value="SSF111342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00312">
        <property type="entry name" value="cbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC73983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="433" mass="46854" checksum="41EB486E4092E2B8" modified="2018-02-28" version="1">MDGDDSCMSNDANADAIPTPTTNTDINTPISVDDPMLKEIEEEQEQELPKDILEKKRKGLLRTGYTTGTCATAAAKAALISLISRGRELPASVTVTLPKGDKATLQVKECIFVASADDDNDREYAVCTVVKDAGDDPDVTHGAEIVAKVEWLDGEPERIEVTGGKGVGIVTKPGLGLEIGKHAINPTPMRMIINAVREVASEHLKQRGVKVTISVPRGEELAKQTDNPRLGIVGGISILGTTGIVVPYSTASFAASIKQCIDVAVAMGDYTIVLTTGGRSEEFARQVIPNLPDHCFIQMGDFVAYSVRQAAMKGIKHIIIAGFIGKLSKAAKGIKQTHVKGSHVDMEFLADVAKECNASMELYEQIRNANTARHVMEIVMANNLQGYFDRLCSKVCERLSSYMEDKASIECIMFDFDGKIIGRASKSMKEVYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBC6</accession>
    <name>A0A2H5VBC6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RECA_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73987">
        <property type="protein sequence ID" value="GBC73987"/>
        <property type="gene ID" value="HRbin05_00015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="DNA_recomb/repair_Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RECA_2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC73987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="290" mass="32322" checksum="3516D61A48BBE17C" modified="2018-02-28" version="1">MQVISTGSRALDALLLGGVRRGLLYCVFGASGSGKTQLCMQLALNSAMANKSARVFIVDAKGDFRPERIIDIYKARMDGGECKRGEGGRSKHGNDTYMNSGREGESGYNADINTIMGIMDRIYVQRAYHVDDIFSSLRDVDSMYERYDHGVSFLIVEDSPSLFRLEYGSKSAEGHFRLMRLMHDLALRAVLRNTAVIVTNGVASSARDEHEGVDTTVTDLEMKERQIMDRSVSMFAHFKVRLERLSSKMKDEEGMKAIVDGSVFRATLLQPLGKNNKALFKIVERGIVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBD3</accession>
    <name>A0A2H5VBD3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73997">
        <property type="protein sequence ID" value="GBC73997"/>
        <property type="gene ID" value="HRbin05_00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012443">
        <property type="entry name" value="DUF1646"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07854">
        <property type="entry name" value="DUF1646"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC73997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="348" mass="37088" checksum="3197454512B6F3AF" modified="2018-02-28" version="1">MVFDGLAVQIATLTALIAIPVVSKKVEHNIEYFFLAVGIVAVSIVGIWSIHLLEEALLHPVMIGSIPIGITQVVLIAGLIFYYNKDKVARFAFRLNNPLMLAVIVFVLGIAASAISAIVASAILAELLALSQFPRSVKVKVAIASAFAIGIGAALLPLGEPLSTIAIAKLKGEPYNATFTFLLENLWDLVIPLVAVFSLLAYFYAKRGSKEVYITEYETSVRDVVMRALKIYAFIFGLTLLGEFFKPLAEPVAALGIVVLYFFGLISAAADNATLTAALVSPEMELGEIRAFMISLVIAGGLLIPGNVPNIIFASILKIGFKEWARLAIPVGLVVFLASGAAIIGLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBE3</accession>
    <name>A0A2H5VBE3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00037</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74007">
        <property type="protein sequence ID" value="GBC74007"/>
        <property type="gene ID" value="HRbin05_00037"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044908">
        <property type="entry name" value="NitrOD5-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="98" mass="11358" checksum="128130CCE8492973" modified="2018-02-28" version="1">MSEEYRDKVIDAVIDTLRSILGEVTVQALEVFMKMNGTSLYSIYDEPDRVTNLLYVLFKSSARFLDDEIVKEVCLRLGHEYNCKVSLNDIINSIKYKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBE5</accession>
    <name>A0A2H5VBE5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Kynurenine formamidase</fullName>
            <ecNumber evidence="1">3.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">kynB</name>
        <name evidence="1" type="ORF">HRbin05_00045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.9" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74014">
        <property type="protein sequence ID" value="GBC74014"/>
        <property type="gene ID" value="HRbin05_00045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="PTHR31118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="230" mass="25831" checksum="D428A82AE4AAF32B" modified="2018-02-28" version="1">MVRMIDLTRTIEYGMPVFEQRIRPTLIPWARLDIHGYDLELMFMSTHTGTHMDAPSHFSRGMSIDEIPLHVLVSNAILAEVKKGEKEYIHREDLARRLEHYDLEGKSIIISTGWEHKWKSPNYLSDNPGLSRDAAEYLVEKGVILVGIDTANIDHPDDKDFTVHRVLLPNNVPIVENLCNLEAINGNGNGNDGGSEGRIRRGRGEFRLIAAPLKIKGCTGSPVRAIAMID</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBF4</accession>
    <name>A0A2H5VBF4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PDCD5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC74013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74013">
        <property type="protein sequence ID" value="GBC74013"/>
        <property type="gene ID" value="HRbin05_00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002836">
        <property type="entry name" value="PDCD5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036883">
        <property type="entry name" value="PDCD5-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10840">
        <property type="entry name" value="PTHR10840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01984">
        <property type="entry name" value="dsDNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015730">
        <property type="entry name" value="TFAR19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46950">
        <property type="entry name" value="SSF46950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="104" mass="12541" checksum="7BC6FCF3EA61A933" modified="2018-02-28" version="1">MDEWIEEVRIGMAQYDNRSEEEKAREMEIRLMRERLLRALLTTEARQRLTNLKMVKPELAKTVEDYIITMGSQGRISRALTDEELKRLLLQIQQPKREFRITYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBG0</accession>
    <name>A0A2H5VBG0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fructose-1, 6-bisphosphatase/inositol-1-monophosphatase</fullName>
            <ecNumber evidence="1">3.1.3.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">suhB</name>
        <name evidence="1" type="ORF">HRbin05_00063</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74032">
        <property type="protein sequence ID" value="GBC74032"/>
        <property type="gene ID" value="HRbin05_00063"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="282" mass="29876" checksum="D0D02C9BF80EA779" modified="2018-02-28" version="1">MDSIMSMLHDICMNVRSKVSKMSREEAGISLARGAGGDITKKIDKVGEDAALEVVREYDVSCRVLSEEAGLVDSGRKGRGGADANASNDDGSCIIVLDAIDGTTNAVRGIPFYSCSVAYATSDRLSSVTHAAVMDLTSGDIYYAVRGNGAYMNGSRIKTANVSSDRAGYVIGINLSGISIDKLKRMSSILAMTNHIRQFGSNALEMCLLARGLLDAYIDVRGKIRVTDIAAACLIIVEAGGIVVDEHLNILDAPLSLDARLSFIASADKSMLNYIFSSIASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBG1</accession>
    <name>A0A2H5VBG1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00057</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74026">
        <property type="protein sequence ID" value="GBC74026"/>
        <property type="gene ID" value="HRbin05_00057"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="56" mass="6817" checksum="EC575CE3BE304BD3" modified="2018-02-28" version="1">MSSEVRFCDRCMRRTRHDIVVEPEMATYKRRRLYRCSICGKESWKRGLRPSSEISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBI5</accession>
    <name>A0A2H5VBI5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Demethylmenaquinone methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.163</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">menG_1</name>
        <name evidence="4" type="ORF">HRbin05_00079</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74048">
        <property type="protein sequence ID" value="GBC74048"/>
        <property type="gene ID" value="HRbin05_00079"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="227" mass="26205" checksum="E9F4295530B16B77" modified="2018-02-28" version="1">MHTGHEIAIRFFKHTSSMYDRVVRLTTFGQDAVWKRVMLRFVPEGDYTALDLACGTGILTLVLRGKVSRVYGLDLMYNSLVIADSKARNLNYYDIVLLNAAAEFIPLRDGTVDIITASYLAKYCDIEKVVMECKRLLRSGGIVVMHDFTYPRGTMRYLWHAYFMLLRLLGRFMYEWRSVFNELDKVIVERRCWVTELIDALNKHGFKDVGCINLTFNTAAVVYARKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBI6</accession>
    <name>A0A2H5VBI6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF87 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00078</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74047">
        <property type="protein sequence ID" value="GBC74047"/>
        <property type="gene ID" value="HRbin05_00078"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF87" evidence="1">
        <location>
            <begin position="28"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="445" mass="50492" checksum="0FC0AFDD7FE99BA5" modified="2018-02-28" version="1">MINNDEIDIIGFSDDGRAYGILSRDRIHTAIFGESGAGKSETMKLLILQCIKRRHGFMLIDAHGTLAREVLMMIPRELWSNTVYINPATAIWFKRVISVNPLECRDEEDKHVVVMSFLNVFKNLYSDSWGDRLETILRNALNVLLDVGKEITLKDLRSFIINQEFRDSILRNVTDLDALHFWYEIFEKNYKKEAVGVVYNKLDKILSTPLAMFILNSRLGIDIGQMMREGKFIVVDLADIASDDIVAFLGSLLIHLVYVEAKRHSRYSTSSPPTPFNLFIDEAHLFPSFAIREVLNTLRKFNVKVTIATQSINSLPDDIAKEIPALCRTIICFKCDIATVTLFKSLLPLSRDEMLSLSLHEFAFYSHSSPPVTGIAMSKKITVKEYNNWLDVARFSVEIHGNDVGSVKRVSDKKMSINLNDEEMSKRNGATLARLDTSNMKTKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBJ8</accession>
    <name>A0A2H5VBJ8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21e</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpl21e</name>
        <name evidence="6" type="ORF">HRbin05_00095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the eukaryotic ribosomal protein eL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74064">
        <property type="protein sequence ID" value="GBC74064"/>
        <property type="gene ID" value="HRbin05_00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00369">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036948">
        <property type="entry name" value="Ribosomal_L21_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001147">
        <property type="entry name" value="Ribosomal_L21e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022856">
        <property type="entry name" value="Ribosomal_L21e_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018259">
        <property type="entry name" value="Ribosomal_L21e_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20981">
        <property type="entry name" value="PTHR20981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01157">
        <property type="entry name" value="Ribosomal_L21e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01171">
        <property type="entry name" value="RIBOSOMAL_L21E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="110" mass="12077" checksum="AEEB7D598F890A4D" modified="2018-02-28" version="1">MARSRGFRRKTRQLLTKDTIRGLSYLLHEYKIGDKVVIDIDAREHKGMPHRRFQGKVGVVEAIGRRALKIRVRIGEKDKMVIARVAHVKPLGIVSSIGSGNSGSSSGSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBK0</accession>
    <name>A0A2H5VBK0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Serine--tRNA ligase</fullName>
            <ecNumber evidence="1">6.1.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">serS</name>
        <name evidence="1" type="ORF">HRbin05_00096</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000002">
        <property type="protein sequence ID" value="GBC74065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74065">
        <property type="protein sequence ID" value="GBC74065"/>
        <property type="gene ID" value="HRbin05_00096"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="85" mass="9844" checksum="1622CE07909440A8" modified="2018-02-28" version="1">MYREVVSCSNCLDFQARRLKIRYRDKPNEETRYVHTLNSTLVATERTLVAMIENNQSEDGKSIIVPKVLRPYMNGIDSIPSPYAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBK8</accession>
    <name>A0A2H5VBK8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trxA</name>
        <name evidence="2" type="ORF">HRbin05_00108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74076">
        <property type="protein sequence ID" value="GBC74076"/>
        <property type="gene ID" value="HRbin05_00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="18"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="139" mass="16112" checksum="598592951931CB04" modified="2018-02-28" version="1">MIGVERDQEIERIMRKKMEEMMRSQQQKGTSNEPKLIELNEQNFDDVINGSKPVIVDFWAAWCGPCQFMLPIFDRLARKYGDRMVFARLNVDENNAVAARYDVYAIPTFIVFKDGKMVDRAIGAVGEMGLERLIKKYIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBN2</accession>
    <name>A0A2H5VBN2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00131</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74098">
        <property type="protein sequence ID" value="GBC74098"/>
        <property type="gene ID" value="HRbin05_00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="407"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="437"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="588" mass="68796" checksum="39359EBBB38C4EC3" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBP2</accession>
    <name>A0A2H5VBP2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
            <shortName evidence="7">Glu-ADT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">gatA</name>
        <name evidence="9" type="ORF">HRbin05_00141</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74108">
        <property type="protein sequence ID" value="GBC74108"/>
        <property type="gene ID" value="HRbin05_00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="8">
        <location>
            <begin position="29"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="86"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="494" mass="53772" checksum="9CA5A8AC3441BC47" modified="2018-02-28" version="1">MVSSSKLALNAYELVEEVKSGSISVEDYIASMLERIESMDERINAYITINHHALDEARMVDKMVKSSSNGSGYGNGNLLGVPLAVKDNISTEGIRTTCASRMLEDYVPVYDATVVKRLKDAGAIVIGKTNMDEFGMGSTTEFSAFGVTHNPWDEDRVAGGSSGGSAASLASCMASIALGSDTGGSVRCPASFCSIYGLKPTYGLLSRYGLISYANSLECIGLMARSAVDLALMLNAVVGADIQNDHTSIDATTIDLESINSTSLKGMRFATIREIMESNAIDEPIRDSMLDAIASVEQLDAIVEEVSIPSLKYALASYYTIAMAEASSNLARYDGIRYGYTVQPDGIAWNEFYSTIRSNFGSEVKRRIMLGTYVLSSGYYGRYYMKAQKARAIIRDEIMHVLRSYNAIITPTMPVLPPRIGERISDPLRLYTIDICTVIANLAGIPALSIPYSMYNGLPIGIQFMAKHLDEATLLRIAYLLEHVRGSKVKRCVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBQ1</accession>
    <name>A0A2H5VBQ1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HRbin05_00123</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74090">
        <property type="protein sequence ID" value="GBC74090"/>
        <property type="gene ID" value="HRbin05_00123"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026392">
        <property type="entry name" value="Exo/Archaeosortase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019127">
        <property type="entry name" value="Exosortase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09721">
        <property type="entry name" value="Exosortase_EpsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04178">
        <property type="entry name" value="exo_archaeo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="242"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="725" mass="81253" checksum="0489B2315D11FB06" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBR1</accession>
    <name>A0A2H5VBR1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Transcription initiation factor IIB</fullName>
            <shortName evidence="5">TFIIB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tfb</name>
        <name evidence="8" type="ORF">HRbin05_00158</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TFIIB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74125">
        <property type="protein sequence ID" value="GBC74125"/>
        <property type="gene ID" value="HRbin05_00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017025">
        <property type="term" value="F:TBP-class protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070897">
        <property type="term" value="P:transcription preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00043">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00383">
        <property type="entry name" value="TF2B_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000812">
        <property type="entry name" value="TFIIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023484">
        <property type="entry name" value="TFIIB_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023486">
        <property type="entry name" value="TFIIB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013150">
        <property type="entry name" value="TFIIB_cyclin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013137">
        <property type="entry name" value="Znf_TFIIB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11618">
        <property type="entry name" value="PTHR11618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08271">
        <property type="entry name" value="TF_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00382">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00685">
        <property type="entry name" value="TIFACTORIIB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="SSF47954"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00782">
        <property type="entry name" value="TFIIB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51134">
        <property type="entry name" value="ZF_TFIIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="TFIIB-type" evidence="7">
        <location>
            <begin position="18"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="repeat" description="1" evidence="5">
        <location>
            <begin position="135"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="314" mass="34708" checksum="086B1CB1E82958FE" modified="2018-02-28" version="1">MLNIRFMVSKMVVDRTLLSDKCPRCGKGPLVTDNATGEMFCGNCGYVVSERIEELGPEWRAFSKEEHEDRSRTGIPTSLAMHDMGLATVIGPIDKDASGKPLSTAIRSTIERLRTWDSRSQVHEPLDRNFRQAFSELDRLKDKLAVGESVIEKAAYIYRKALEKGLVRGRSISALVAAALYAACRDTETPRTLKDIANASNIKKKDIARCYRLLIRELDLQMPVVDPIKCVSRIASKAGLSEKTKRTAIEILKRAEEAKISAGKDPMGLAAAALYVACVMHGENKTQKDVAEAAGVTEVTIRNRYKGLKLALKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBR4</accession>
    <name>A0A2H5VBR4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein translation factor SUI1 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00162</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74129">
        <property type="protein sequence ID" value="GBC74129"/>
        <property type="gene ID" value="HRbin05_00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11567">
        <property type="entry name" value="YciH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005872">
        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037511">
        <property type="entry name" value="Transl_init_SUI1_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="SSF55159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="5">
        <location>
            <begin position="27"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR037511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="101" mass="11397" checksum="74AA5A383E631F84" modified="2018-02-28" version="1">MSVICKRCGLPQDLCACGELEKEESKIVVRLEKRRFNKDITMIEGIGDLGDIDKIVKHLKSRLACGGTAKDGYVMLQGDHREQVKKYLIELGFNESSIEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBS9</accession>
    <name>A0A2H5VBS9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00179</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74146">
        <property type="protein sequence ID" value="GBC74146"/>
        <property type="gene ID" value="HRbin05_00179"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="121" mass="12444" checksum="8711B2B65AA81183" modified="2018-02-28" version="1">MLKIAKGLVIAALVLLIIYGVDEAASRSMDGEGAKETGFLPVNAMVRGLAFGGSAIALSIATFFIAREVSTFVWIMLIINGVLIAIGGAVAGSAPVTGLGALVIALGIIKRFRDAKIARMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBT1</accession>
    <name>A0A2H5VBT1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">trpD</name>
        <name evidence="6" type="ORF">HRbin05_00153</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74120">
        <property type="protein sequence ID" value="GBC74120"/>
        <property type="gene ID" value="HRbin05_00153"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="5">
        <location>
            <begin position="5"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="4">
        <location>
            <begin position="74"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="90"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="108"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="353" mass="38290" checksum="B7B15F3CF4F13C32" modified="2018-02-28" version="1">MSVRDALRKVLDMQSLTYEEMCACMESILAGEASDVLIAALFTALRMKGESIDELNAMLDVMLKHAIKVRVDGYVIDTSGTGGDNAGTFNISTAAAFIASASGIKVAKHGNRAVSSMSGSADILEYLGYNLDTKPEKVEWCIEHISIGFIFAPRFHPAMSRVAGVRREMGIRTAFNIVGPLCNPALPRAQVVGVYSPTIMDKVAGMLIHAGREEFMVVHAIDGMDELSNTCINRILWYRHDAGSINVDLDPKTLGLSTARKDDLMVRSRDEAAGIFLDVLKGSARKEVIDAVLLNAAAALIVGRKAPSFKEGIEVAKASVMDGRAYKRLRELIGACGSIERLDEVEDMIARKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBT2</accession>
    <name>A0A2H5VBT2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00182</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74149">
        <property type="protein sequence ID" value="GBC74149"/>
        <property type="gene ID" value="HRbin05_00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="258" mass="29222" checksum="DC9FDF70F9E76D64" modified="2018-02-28" version="1">MIDSISNKKHMLLYAGAIATLVISASLIFNAIAGPKLEYARLEISRYDMNIIWSHRGKDVPGNIIRCPLPQEEEKRLGFVTLTLDDLNKVPKLKQAIDEVEASLEYAVQHGYLEYSAKVDREGNVIENKPWREYYWIKDENGCYNDMWHALGLMSEQPVGGGTAVATLTEDEYKAIKSMIYNAYRTQHTQEELNRLAELYKGFRPSDPSVNATPTDLLESQMVTKDYADMSSAYLGFFTALIKVDGKYYGIAINTLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBU5</accession>
    <name>A0A2H5VBU5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00197</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74163">
        <property type="protein sequence ID" value="GBC74163"/>
        <property type="gene ID" value="HRbin05_00197"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="68" mass="7034" checksum="19E8104656AA1E0F" modified="2018-02-28" version="1">MNVVLDGNVVTARFASTDVLTPTTNSNIPVFCPVSLKKALGLMVNVGAINILLLAGIRSTLVGSMFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBV1</accession>
    <name>A0A2H5VBV1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Putative acetyl-CoA acyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00173</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74140">
        <property type="protein sequence ID" value="GBC74140"/>
        <property type="gene ID" value="HRbin05_00173"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="1">
        <location>
            <begin position="55"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="2">
        <location>
            <begin position="263"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="384" mass="41104" checksum="4F7ACA812BD777CD" modified="2018-02-28" version="1">MGDADVNVNTNANVAIVGYGLARFNRDEASKYSLYELALQSVVDMFSNMEYDVRSLKDGIDALITSTTDSSTYTASILADMLGIRARIVNRVESMCSSGADALIAAYSYIASGLSNLALVVGFDSSNSGMLLDWDVARGDMRHPAHWAALYAKKHMQEFGTSREHLAMVAVKNRRSALTNEKAYFYDKGAVDVDDVLRSKPVVEPLRLYDCSIACNGAASILLASADIAKSVCREPVWIKGIGSSSIGASINSIDLTTMHVTVDAARQAYKMGNVRPEMVDVAQVHDSFTILEILAYEDLGFVEKGKGGYAVEGRIGIPAVNTDGGVLGRGHSSGATGIAQVVEVTRQLMHKAGSRQIKDCRIGLVHNMAAAGTHASVILLVRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBV7</accession>
    <name>A0A2H5VBV7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Threonine synthase</fullName>
            <ecNumber evidence="5">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thrC</name>
        <name evidence="9" type="ORF">HRbin05_00208</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + O-phospho-L-homoserine = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74174">
        <property type="protein sequence ID" value="GBC74174"/>
        <property type="gene ID" value="HRbin05_00208"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026260">
        <property type="entry name" value="Thr_Synthase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038945">
        <property type="entry name" value="Thr_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="8">
        <location>
            <begin position="71"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="413" mass="45122" checksum="73BE88ED8E86536C" modified="2018-02-28" version="1">MGIVNALRCRECKQEYEPTLKYICDECLGPLDVTYDYGSIKVNRDTFANREKSYWRYFELLPIAEKANIVSLEAGFTPLHRADRLADALGLRAGNLYLKNDSVNPTFSFKDRPAGVAVSKAREMGLKAVGCASTGNLASATAAHAAKADLPCYIFAPKDIEYAKIAQALAYGAEFIAVDGTYDDANRIAAQISDAKPIGIVNVNLRPYYVEGSKTLAYEVVEQLNWKVPDHLIVPVASGAMLNAICRGLEELYELNLVDGIDNVKVTAAQAKGCSPIVEAFKGNRDEIVPVEYPNTIAKSLAIGDPGDGIYALRRLRQFNGYAEDPDDDEIRDAILLLARYEGIFTEPAGGVAVASLKRLVEDGRIDKDEHVVCYITGNGLKSIDAIEGLLRKPRIVKPNYMDVVEMISIAGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBV9</accession>
    <name>A0A2H5VBV9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quinoprotein glucose dehydrogenase B</fullName>
            <ecNumber evidence="2">1.1.5.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gdhB</name>
        <name evidence="2" type="ORF">HRbin05_00216</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.5.2" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74182">
        <property type="protein sequence ID" value="GBC74182"/>
        <property type="gene ID" value="HRbin05_00216"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008876">
        <property type="term" value="F:quinoprotein glucose dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSDH" evidence="1">
        <location>
            <begin position="45"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="364" mass="40107" checksum="6B466AC1BB56CB03" modified="2018-02-28" version="1">MMMSRLLIAGLIAGATVMALLLALPRGGVPLPEPEKRLEVIAKNLEVPWSMDMDHDDGILYFTERVGRLNIIDKDGAVRTIYSREVASIGEAGLLGLALDPEFKSNGYIYLYYTYSTESGLFNRVVRLEKVGADGNYREHVLLDGIPGGEIHNGGRIKFGPDGMLYITTGDAGRAELAQDVNSLAGKILRIRKDGSIPEDNPFNNAVYSYGHRNPQGLAWHPTSKNLYATEHGPVAEDEINLIRKGANYGWPIETCSKAERYEKPILCYTVSIAPAGAAFAEYGGSMSLFYATLRGQHVERIVFDEGENIVRIENFLTGLGRIRDVYASKDGYLYIATSNRDGRGIPIGDDDRIVRVRLTDITG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBX7</accession>
    <name>A0A2H5VBX7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA sulfurtransferase</fullName>
            <ecNumber evidence="5">2.8.1.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">thiI</name>
        <name evidence="5" type="ORF">HRbin05_00230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.4" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74196">
        <property type="protein sequence ID" value="GBC74196"/>
        <property type="gene ID" value="HRbin05_00230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004810">
        <property type="term" value="F:tRNA adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140741">
        <property type="term" value="F:tRNA U4 sulfurtransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020536">
        <property type="entry name" value="ThiI_AANH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02568">
        <property type="entry name" value="ThiI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiI" evidence="4">
        <location>
            <begin position="33"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="8"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="366" mass="40570" checksum="0289ACCB78DC572F" modified="2018-02-28" version="1">MLGRDNKMSEYYNNNNNNSKSDNGKDKTTSKVRCVALLSGGLDSTLAVKMMKDMGVEVKALAVKTPFCDFDCGKGCGFRVKEVADALGVELKTVYLGEEYIEMLKRPKYGYGSGMNPCIDCRAMMYKLAKEYMEECGADFIVTGEVLNQRPMSQNMRALRIIERESNLEGKVLRPLSAKHLKPTEAEVKGLIRRDMLLGIKGRSRKVQMELARQLGLDAPNAAGGCLLTDKQFARRVRDLLDHVSNPTLNDVELLKVGRHFRLCNDAKLVVGRNKDENELIQALMQDGDIMLEPKDVKGPKALLRYNNGKGDEGEGEEEVLALAASIVCRYSDADGPCIVVVSDGITTKEIKSEPIADAMLESYRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBY5</accession>
    <name>A0A2H5VBY5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00124</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74091">
        <property type="protein sequence ID" value="GBC74091"/>
        <property type="gene ID" value="HRbin05_00124"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="29" mass="3342" checksum="0175BB0B382D4F28" modified="2018-02-28" version="1">MSMDSLNVGILVVNKIDTIMLIYLQWFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBY7</accession>
    <name>A0A2H5VBY7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-methylaminobutanoate oxidase (Formaldehyde-forming)</fullName>
            <ecNumber evidence="2">1.5.3.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">abo</name>
        <name evidence="2" type="ORF">HRbin05_00240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.3.19" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74206">
        <property type="protein sequence ID" value="GBC74206"/>
        <property type="gene ID" value="HRbin05_00240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102317">
        <property type="term" value="F:4-methylaminobutyrate oxidase (demethylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="4"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="389" mass="43546" checksum="2198F26BF1444F5B" modified="2018-02-28" version="1">MRVDVVVVGAGIAGLSVAEAMLNKGMKVCIIEAKHAGYGATGRSAGIATVQMNDTLDVRLAKKGIDIINAWRRRYNLDEILSTTGLLSIDRQGSIMKYAKLFSECEVAYEVMDVREAMDRWPWLKFNVDGVDAEECIYTKDDVCMDPLVFASVFADRLKDMGVEFATGRVDIQSMMVDGEHVTLRFDDEHVVADTLVLCTGAWSKGIGRWLGYAPTTILKVPLIFFKYDIGEHDMVLPFADEINHTYWIPSRAGMLVGADYTVWDVNEAEDALGEEFRVKEGVHVDDYLLKYIKHVRELLVKRINFHVYESKVHFGPISITPDGRPIVGRVPEFKNLYILDGLRGYGLARAPALAYMLVEHILDGTEIVGELGPTRFIGTNDTWLIQEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBZ0</accession>
    <name>A0A2H5VBZ0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74205">
        <property type="protein sequence ID" value="GBC74205"/>
        <property type="gene ID" value="HRbin05_00239"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="23"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="211" mass="24432" checksum="335A1737705F49CF" modified="2018-02-28" version="1">MQLVEVQVDDDGDRWERRMSATSNLKEDHLIVRRIRNIAKEYAEIIYSSNSVPVDDVKRVLILIEVFIDAYHHCKEECSYFPAVNGTMLEDEAKALAIEHELGRRIARMLNSNLDLWLRDDSNSEPVARMLKAYAEYLDVHIDREERFFSSYDAVVHEQEQVIDAFNAIRKERMDDARLNSILSMLDKLEGSLARMKESVVVGKEGDGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBZ7</accession>
    <name>A0A2H5VBZ7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00251</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74216">
        <property type="protein sequence ID" value="GBC74216"/>
        <property type="gene ID" value="HRbin05_00251"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="383" mass="42251" checksum="44AA538DC336B01A" modified="2018-02-28" version="1">MKRVTTYVTSLLLAAVLSISSIVTAHAQTTWYPGKGAELGTYFVYTIRDLEYESGRELEVAIWLGSRDDQGNWIADVSINDAGAVSNGKMVLSSINMQPQSAEPSVSKYRAIIQRTLAWLGDFANSGDPKPLAPSAWGRLAITGGVPVGVGAPVNLQVTNEQVTAANTTWNTTIVGFRYAKDSKIWVAENFPLPIKAEVYAFRTEEPIPLQYSFELKRFGRSDKPIELTPGVVEIPKPPLEKFGSTGNVYMLLYWGPQTIMPGQDVQIAAQLYDAGKRPLKETERYTIEIFDGDKSILKQELSNNLQPVTVRFESEGVKKVVVSYIVPFRTGEGETHLIDRTEFNIVVVPEFPVAIMAIVASIMAVMIAVTRGRLGSILNRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC00</accession>
    <name>A0A2H5VC00_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00257</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74222">
        <property type="protein sequence ID" value="GBC74222"/>
        <property type="gene ID" value="HRbin05_00257"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="93" mass="10831" checksum="DECDFCD7D6E96070" modified="2018-02-28" version="1">MSTDEAYIYYILQKVNGYPLLVSIHTIPAKYDSSIARQIFYVYEEDRVYIAYESEPRIFGSFFYHVLINLQYILVITITVCIIALLLASRGHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC09</accession>
    <name>A0A2H5VC09_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00144</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74111">
        <property type="protein sequence ID" value="GBC74111"/>
        <property type="gene ID" value="HRbin05_00144"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="68" mass="7639" checksum="F578B18C3B183E99" modified="2018-02-28" version="1">MGKVGKGVRCSVVECSNNAVRSLDAGKVRGSGLDVSEGKRVYLCEEHYKQWKKVFKQSKSDDISIRYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC24</accession>
    <name>A0A2H5VC24_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">16S rRNA aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HRbin05_00272</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>an N(1)-methylpseudouridine in 16S/18S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-methyl-N(3)[(3S)-3-amino-3-carboxypropyl]pseudouridine in 16S/18S rRNA + S-methyl-5'-thioadenosine</text>
            <dbReference type="Rhea" id="RHEA:63296"/>
            <dbReference type="Rhea" id="RHEA-COMP:11634"/>
            <dbReference type="Rhea" id="RHEA-COMP:16310"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74890"/>
            <dbReference type="ChEBI" id="CHEBI:146234"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TDD superfamily. TSR3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="7"/>
    <dbReference type="EMBL" id="BEHH01000008">
        <property type="protein sequence ID" value="GBC74237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74237">
        <property type="protein sequence ID" value="GBC74237"/>
        <property type="gene ID" value="HRbin05_00272"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106388">
        <property type="term" value="F:18S rRNA aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01116">
        <property type="entry name" value="TSR3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022968">
        <property type="entry name" value="Tsr3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007177">
        <property type="entry name" value="Tsr3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20426">
        <property type="entry name" value="PTHR20426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04034">
        <property type="entry name" value="Ribo_biogen_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Ribo_biogen_C" evidence="8">
        <location>
            <begin position="69"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00014114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="205" mass="23193" checksum="D61599D5E708B08E" modified="2018-02-28" version="1">MIVQVQGYMEGVDVETVGMRGAAASNMHKHEPSLLVYMLSDDDPSKCSANKLLRFNMVKRVNRVPYRTILLDPYSNIPLLNSDGDECTSITLIDCSWVNARRVFARIKVLKRRRLPLLLAANPINYAKVAKLSSVEALAAACYILGYQHLAYELLAKFKWGSTFITLNHELLEEYSRAGSIEDVVRIEHEYSLTEVLDRIDLIGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC26</accession>
    <name>A0A2H5VC26_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Dihydroorotate dehydrogenase</fullName>
            <shortName evidence="8">DHOD</shortName>
            <shortName evidence="8">DHODase</shortName>
            <shortName evidence="8">DHOdehase</shortName>
            <ecNumber evidence="8">1.3.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">pyrD</name>
        <name evidence="10" type="ORF">HRbin05_00278</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of dihydroorotate to orotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(S)-dihydroorotate + A = AH2 + orotate</text>
            <dbReference type="Rhea" id="RHEA:18073"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="8">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.-.-" evidence="8"/>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74243">
        <property type="protein sequence ID" value="GBC74243"/>
        <property type="gene ID" value="HRbin05_00278"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04740">
        <property type="entry name" value="DHOD_1B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00224">
        <property type="entry name" value="DHO_dh_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033888">
        <property type="entry name" value="DHOD_1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024920">
        <property type="entry name" value="Dihydroorotate_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01037">
        <property type="entry name" value="pyrD_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="9">
        <location>
            <begin position="3"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="68"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="205"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="44"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="255"/>
            <end position="256"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="277"/>
            <end position="278"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="317" mass="34203" checksum="4A9E6F4E9D3AD3D9" modified="2018-02-28" version="1">MDLSVEFAGIRIRNPTILASGILGISYEVMKRVYDAGAGAVVSKSISVEPREGYKGPIIVKVDSGYVNAVGLANPGVDHFVQELSRYGYDKESEDAIQDRSSYDNYRIPIVVNLVGSSVDEFVSMVKRLDHLSIIGYELNLSCPHVERVGLEVGDDPELVSRIIKGIRAVTSKPIIAKLGLGAVDMLEVAKTAIDSGASAVTAINTIRAMVIDAETCMPVLSNKIGGLSGRAIKPIALRCVYELHRAGVPVIGCGGIYDWRDAVEFMLAGAHAVQIGSAIGDRWLDVFKEVNDGIKEYLARKSLKSVKEVVGIAHRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC28</accession>
    <name>A0A2H5VC28_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">High-affinity zinc uptake system binding-protein ZnuA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">znuA</name>
        <name evidence="3" type="ORF">HRbin05_00284</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74249">
        <property type="protein sequence ID" value="GBC74249"/>
        <property type="gene ID" value="HRbin05_00284"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="326" mass="36590" checksum="20DCF00F3591C296" modified="2018-02-28" version="1">MGIDNKKVVIGAIASTVVIVLASVVAITLQGSNNNNSTSSDVTLPTSENVSRDHLLQDANKGKRLKIMTTFYPLYEFAKAVVGDRADVDLLIPSGLEPHDWEPSARDLERLKDYQILIYNSAIFEPYIDKVKGLGYDLKMVEAASGMVLDQDPHVWLDPILAKEQVRIIRDAIASMDSDEGNSRYYDENARAYTVRLDELHVKFEEGLRDCGRREFITLHSAYNYLVSRYGLKQITITGIEPEHDIPAGKIREIVDLAKRHGIDVVYAEEGIDDRLVRALAEEINAKVLTLSPIEVLDEEDLEEGKTYIAKMEENLENLRLGLGCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC36</accession>
    <name>A0A2H5VC36_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74253">
        <property type="protein sequence ID" value="GBC74253"/>
        <property type="gene ID" value="HRbin05_00288"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="163" mass="17220" checksum="C34769796E539ED2" modified="2018-02-28" version="1">MMQKRAIKPYPFILMTGVALLLTGLTNDAMAYGLTVNPDTLSINGTATAELCAGTTSLTITSVELVDPTGASHSSSVNVGTTLNAGDCVTWNIPDDFSSTTLNAIGTWVLRINTNPGNQFTDEFNVSIFVVPESILGAIAVASASLITFAGYTLIGRIRRHHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC45</accession>
    <name>A0A2H5VC45_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="7">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">t(6)A37 threonylcarbamoyladenosine biosynthesis protein Kae1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA threonylcarbamoyladenosine biosynthesis protein Kae1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">tsaD</name>
        <name evidence="7" type="synonym">kae1</name>
        <name evidence="9" type="ORF">HRbin05_00292</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="7">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="7"/>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74257">
        <property type="protein sequence ID" value="GBC74257"/>
        <property type="gene ID" value="HRbin05_00292"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000408">
        <property type="term" value="C:EKC/KEOPS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01446">
        <property type="entry name" value="Kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022449">
        <property type="entry name" value="Kae1_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034680">
        <property type="entry name" value="Kae1_archaea_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF14">
        <property type="entry name" value="PTHR11735:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03722">
        <property type="entry name" value="arch_KAE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="8">
        <location>
            <begin position="25"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="130"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="334" mass="36133" checksum="2E351C4A6C9BEC84" modified="2018-02-28" version="1">MTICLGIESTAHTFSCSLVDEQNILSDVRSIYKPPEGSGIHPREASRHHAEESANVLREALATAKVSIKDVDVLAYSAGPGLGPCLRVGAVVARCLASYHAKPLVPVNHAVGHVELGIRLTHARDPLVLLVSGGHCMILLFSSRRWRVIGETLDITPGQLLDQFGRELGFASPCGARIEELAAKSSKYIRLPYTVKGNDVSYSGLLTAAKKALSSNRVEDVCYSLQETAFAMLAEATERALAFSRKDELLVVGGVAANRRLAEMLATICDRQGARLHVVPIRYAGDCGAQIACTGLEAYKAGIMVEPIKAFVRQSWRIDATDVPWREQSIKISS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC57</accession>
    <name>A0A2H5VC57_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetylornithine aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">argD</name>
        <name evidence="3" type="ORF">HRbin05_00311</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.11" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74275">
        <property type="protein sequence ID" value="GBC74275"/>
        <property type="gene ID" value="HRbin05_00311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003992">
        <property type="term" value="F:N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="409" mass="45337" checksum="85C943D6F6399713" modified="2018-02-28" version="1">MKHKIVVEPPGQNARTIIDTMSRNCYNSTFVYPLVIEDGEGCYIKDVDGNVYLDFTSNIGSSPLGYKHPDVMDVLKEYSNTGVHKIAGQDFYCREHAELAERLLSIVPKGFKAFLINSGAEAVENAIKIAYRRMGALPGVSCINAFHGRTLGALTFTFSKPVQKNNFPELPVKRIKFCSNDDDPEIDAVENLLKENKVAFIITEIVQGEGGYNVASKRFIKMLREYTSRYGVPLIIDEVQSGMGRTGRWWAFEHYGVEPDIMAVAKALQVGATLYRRELDPGQQGVLSSTWGGGSRIDLAVGARIIDVIRRDNLLSNAERIGGIILKALRDMADDSNGKVVDVRGIGLMIGVEFISKEVRDSFLINAFKHGLLLLPAGIKVIRVIPPLIIREDEVQEGVELMYEVLKGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC66</accession>
    <name>A0A2H5VC66_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00323</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74286">
        <property type="protein sequence ID" value="GBC74286"/>
        <property type="gene ID" value="HRbin05_00323"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="162" mass="18843" checksum="3DE463616E344878" modified="2018-02-28" version="1">MSFTAMLDDLYRVIDEERSRLKQIRNVLKLYNELSRISEAIGSRYGVMLVVSLFDTKKVLAFDTYGKENVTVVIDKFRTKLGIHKDVIKSKAREVFRDDVVEIRDAMAYDNNEGVKIFFSNGRIDVLPGSFHVWRSIDARVKEFCDWLMKECYKVGDGSRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC72</accession>
    <name>A0A2H5VC72_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rpl24</name>
        <name evidence="4" type="ORF">HRbin05_00331</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Located at the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="2">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74293">
        <property type="protein sequence ID" value="GBC74293"/>
        <property type="gene ID" value="HRbin05_00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_A">
        <property type="entry name" value="Ribosomal_L24_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005756">
        <property type="entry name" value="Ribosomal_L26/L24P_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11143">
        <property type="entry name" value="PTHR11143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16906">
        <property type="entry name" value="Ribosomal_L26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01080">
        <property type="entry name" value="rplX_A_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="3">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="120" mass="13891" checksum="8A35B5CE148C706B" modified="2018-02-28" version="1">MKRSLARLKQIYSAPLHVRSKQVCSTLSEELRRQYGRRSVRVRKGDTVRVLRGEYKGVEGKVQRVHVKDGRLEIEGLQREKVRGDKVPVLVHASKVMVIALDMEDKMREAILRRGKDKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC73</accession>
    <name>A0A2H5VC73_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AP-4-A phosphorylase</fullName>
            <ecNumber evidence="4">2.7.7.53</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00321</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.53" evidence="4"/>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74284">
        <property type="protein sequence ID" value="GBC74284"/>
        <property type="gene ID" value="HRbin05_00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HIT" evidence="3">
        <location>
            <begin position="22"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="2">
        <location>
            <begin position="117"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="170" mass="19811" checksum="1D890BC147321DAD" modified="2018-02-28" version="1">MERLWAPWRIAYIERPSDEQCIFCTKPREGRDRKNLILMRGRHVFVILNAYPYTNGHLMITPYRHVADPREVNDEEYAEIFSYLRLCISILKDALKADGFNIGMNIGKVAGAGIADHLHMHIVPRWNGDTNFMPVVGDTRIIPEYLERTYERLLLDLPEEEKAKLVNQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC77</accession>
    <name>A0A2H5VC77_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00324</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74287">
        <property type="protein sequence ID" value="GBC74287"/>
        <property type="gene ID" value="HRbin05_00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="91" mass="9652" checksum="4D8E8E2F9BA98721" modified="2018-02-28" version="1">MEISYRTLVLFIGALAAAIVGIWIGLSPTGVVPVTITEDVVITHTLDDGSCIVDTTDTVLSAKTVRNCNLKEGTKITVSYEKGSAEARMIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC80</accession>
    <name>A0A2H5VC80_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpl4</name>
        <name evidence="5" type="ORF">HRbin05_00340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74302">
        <property type="protein sequence ID" value="GBC74302"/>
        <property type="gene ID" value="HRbin05_00340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_A">
        <property type="entry name" value="Ribosomal_L4_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045240">
        <property type="entry name" value="Ribosomal_L4_euk/arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019970">
        <property type="entry name" value="Ribosomall_L4-archaea"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19431">
        <property type="entry name" value="PTHR19431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03672">
        <property type="entry name" value="rpl4p_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="272" mass="29759" checksum="907E1077BB147F5F" modified="2018-02-28" version="1">MMSVSVYSLDGSKVEQVELPRVFLTPYRMDLIHKAFVHIQSKLFQPQGRDPLAGMRVSAESRGTGLGIARMARVKGEGMRRAGQAGGVAGVVKGRLTHPPRAEKVIVKRLNKKEKHLALCSAIAATMMREVVKARGHRIPDDIELPLVVTDDIEGVKKSKDLLKVLNALRLTDDLERARASIKKRSGKARMRGRKQYIAKSALIIVKNADSIARAASSIPGVEVVPVSRLSILHLAPGGHAGRLCIWSKGALESIRDMSNNAIELMKEVMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC82</accession>
    <name>A0A2H5VC82_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">50S ribosomal protein L3</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplC</name>
        <name evidence="6" type="ORF">HRbin05_00341</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74303">
        <property type="protein sequence ID" value="GBC74303"/>
        <property type="gene ID" value="HRbin05_00341"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045077">
        <property type="entry name" value="L3_arc_euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019928">
        <property type="entry name" value="Ribosomal_L3_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044892">
        <property type="entry name" value="Ribosomal_L3_dom_3_arc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11363">
        <property type="entry name" value="PTHR11363"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03626">
        <property type="entry name" value="L3_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="328" mass="36644" checksum="ED4526535821254D" modified="2018-02-28" version="1">MGHRKHSAPRRGSLAYLPRARAKSIESRIRTWPEIDAKEPRLLGFAGFKAANIHLISIDDRERTPNFGKPLMSRATVIVTPPMRVIGIRAYEKSVYGLRSLFDIYADGLPKELARKVKIKPTEQSSLNDIKLDGVHEVRAIVAVTPRAAGLEQKKPFVFEVGVGGGKDVKARFEYLKNLLGKDVRINEVFKTGEYVDVSAITKGKGFEGPVTRWGIKRKQHKSRKSVRAVGTLGPISPATVMYTVPRAGQRGFHQRLEYNKRILMIASVDEQNITPKGGFMHFGIFKGDYIVVRGSIAGAIKRLVKLRYAIRPKVKKVVEPKIVEVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC87</accession>
    <name>A0A2H5VC87_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00343</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74305">
        <property type="protein sequence ID" value="GBC74305"/>
        <property type="gene ID" value="HRbin05_00343"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18086">
        <property type="entry name" value="HsC9orf114-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003750">
        <property type="entry name" value="Put_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12150">
        <property type="entry name" value="PTHR12150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02598">
        <property type="entry name" value="Methyltrn_RNA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="199" mass="22650" checksum="ABFF15B57A214E3D" modified="2018-02-28" version="1">MRELRYAGLFPPLKAPHHKPYVRMDEVKVDDVRQGVVVRRMRDGYYVDVGLDEPVLLEHADKVKVGERVSVIFTSPYPDLRCRIAREGEIKGYWGYHVRYAGTASDLLKGLSSKKKGGESLAIITSKLGRPVREIEHDIAMARDMMLIFGSPYKDVYEIAGNVRIDMPTYNFFPMQKVESVRLEEAILGCLAVVNYIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC97</accession>
    <name>A0A2H5VC97_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Copper-bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00342</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74304">
        <property type="protein sequence ID" value="GBC74304"/>
        <property type="gene ID" value="HRbin05_00342"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Copper-bind" evidence="2">
        <location>
            <begin position="241"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="321" mass="36427" checksum="18B27496B1BC8698" modified="2018-02-28" version="1">MNWLKKRGVLPLLLSAIVIIISSISVYIVLSYYLRPTDNHVENNTGLFNATNSSTSTPSALHSLSHPNLTISAVNERAGTALTITLQDAHIIDMINRWLDSGAQVTVVGVQPVELPADIKISAPHRNPVHHELIGMILKPLLKPMLDNLREEVSNNNTYKSNRYGEVVITINWHIMGSHQYPVSAVVDLEREKDKVYEIHQQITRVIVDIDERRVKDIIMGEETVIRHDIKPNKIYMESNSFMPYTVIIKPSTILYWHNYSTLSHNIVGIYKTLDGSSILIDSKDIGGGEIWQYLFTKEGEFEYHCTYHKDEGMSGKVIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC98</accession>
    <name>A0A2H5VC98_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ORC1-type DNA replication protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HRbin05_00357</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in regulation of DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the CDC6/cdc18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74319">
        <property type="protein sequence ID" value="GBC74319"/>
        <property type="gene ID" value="HRbin05_00357"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08768">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01407">
        <property type="entry name" value="ORC1_type_DNA_replic_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015163">
        <property type="entry name" value="Cdc6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014277">
        <property type="entry name" value="Orc1/Cdc6_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09079">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01074">
        <property type="entry name" value="Cdc6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02928">
        <property type="entry name" value="TIGR02928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="58"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Cdc6_C" evidence="5">
        <location>
            <begin position="309"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="70"/>
            <end position="74"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="396" mass="44455" checksum="6370DD6B16A5A2CD" modified="2018-02-28" version="1">MEYDNLIDEIFNRVVTSKPLIKDRDVLRSDYVPDRLLYRDDEIRAVAESLSPLLKGSRASNLLLYGKPGTGKTAVARYVLKHLQERARRYNLNVALAYSNVKNAKREYTVLVQLGEAIGLRFPFTGLASSEIFTRIVNHIDEHGIDTVFVLDEIDFLVKKHGDEILYQMTRANERLHKGSLGLVGISNDLNFKDMLDPRVLSSLSEEEVLFSPYTVDELKHILMDRAKLGFNEGCISDAAINLCAAIAGAEHGDARRALDLLRVAGEVAEREGADMVEERHVRIAEKRIEQDKVSETLRKLPLHEKLVIVSVMLSNKGSTGDVYDTYISLAKRLGVQPVTQRRVGMIVSELDMQGLLYAPVVNQGRYGRTKRISLAIQDSLVREVLAEDPMLAVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCA4</accession>
    <name>A0A2H5VCA4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00363</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74325">
        <property type="protein sequence ID" value="GBC74325"/>
        <property type="gene ID" value="HRbin05_00363"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045509">
        <property type="entry name" value="HD_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19276">
        <property type="entry name" value="HD_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="53"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="438" mass="49923" checksum="52B00BF1E9C543FC" modified="2018-02-28" version="1">MRAVAEISDPIHGYFYLSSVEKDIVDSPLFQRLRRIRQLASAYLTYPSAQHTRFEHSLGAMHLAGYAGNVLKDKEYVSSDDVQMLRLAALLHDIGHGPFSHLFEEVLEVKSNITHEDIGRMIIRKSAISDILAKHGYRADEISDLAFGQSSRMFLNEIISGGLSVDLMDYLQRDAYFTGAHYGRIDAERIISSLEVYDGRLAIDRAALNSFESLLIARYQMFKAVYFHKTVRAAEVMLLKAMMLADGHLHLSESYKRVEDYMRLTDDMTLANLLMLKVDVNNNNDKDDSNIKELRLAKRLAEDYRDRRLFKSVFESILQASSRLINRLTDARYLKDRCDEIAGIAGVDPDMVYIDSAKAPSIPRAPGKEEPRDLILVGKEPFRVKRIELKDIPLISSILGYMNMIRVYTIEEHREKVAKAALSVFGSEAESWYERIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCD6</accession>
    <name>A0A2H5VCD6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00387</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74347">
        <property type="protein sequence ID" value="GBC74347"/>
        <property type="gene ID" value="HRbin05_00387"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="164" mass="19014" checksum="1E897FFA972E8180" modified="2018-02-28" version="1">MPYLRDKNGRLGRFLKRYRQVILFNKNLLISGTGGFFASAYISQVHLEYYDDKLANSILALAIEYAVYIPLFALLFYIDNRSRYIDPVTCKRNSKALKDDVKRLFAAFSVAEITFSITRFVSQYQLLLQADIQAYQASMLGSMIAWIVFFIVINLMARIVRLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCD9</accession>
    <name>A0A2H5VCD9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00368</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000013">
        <property type="protein sequence ID" value="GBC74330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74330">
        <property type="protein sequence ID" value="GBC74330"/>
        <property type="gene ID" value="HRbin05_00368"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="82" mass="9043" checksum="59F0E502BABDD3AB" modified="2018-02-28" version="1">MIMPLTVVDPALLQTLLPVIVVIISIINALAGKIARGGYFKTVWFNLGIYIMLGSVTMYTTDIFMSKLMELVMSIDPTSIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCE4</accession>
    <name>A0A2H5VCE4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00402</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000014">
        <property type="protein sequence ID" value="GBC74362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74362">
        <property type="protein sequence ID" value="GBC74362"/>
        <property type="gene ID" value="HRbin05_00402"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="140" mass="14970" checksum="AA865296A8A85E4B" modified="2018-02-28" version="1">MRSPKSTSSIEPTEMNALNPIFSFTAQSTIAEPRAPLWEMKATFPGFGVLLRNVALRLLLGLIMPRQFGPIMFRAYLSLASIIFASNALPSSPTSLNPAEIMMRFFTPALPHCSTIPGTVGAGVAITARSTLSGISSTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCF5</accession>
    <name>A0A2H5VCF5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74375">
        <property type="protein sequence ID" value="GBC74375"/>
        <property type="gene ID" value="HRbin05_00415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050504">
        <property type="term" value="F:mannosyl-3-phosphoglycerate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051479">
        <property type="term" value="P:mannosylglycerate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012812">
        <property type="entry name" value="Osmo_MPG_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09488">
        <property type="entry name" value="Osmo_MPGsynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02460">
        <property type="entry name" value="osmo_MPGsynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="404" mass="46032" checksum="435E7E33B4A7EAF8" modified="2018-02-28" version="1">MKLDYARYSERFGALTINSVQHVHELDSGNAEYHRSRTVAQISERELYDMYNRLAVVVPVKNERLKLLEGVISGIPHDCLVIVVSSSSRNPVDRYKLERDTLKHHVLLTDRDVILVHQKDPELAHVFEALNYPYILDGRMVRDGKGEGMLIGLLIAKMMGKEYIGFIDSDNYIPGAVNEYVKIYAAGMLISESPYTMVRIAWRYKPKVAQGGLYFAKWGRISEYTNRYLNMLISSHTGFETDVVKTGNAGEHAMSMRLAELLDYSSGFAIEPYELVYMMEEFGGVLESRHAEAMYEGVNVLQIESRNPHLHEEKGPSHIREMLRDSLASIYFSKLCTPSLKKQILKDLRRAGAIRSKDDMQSPLLMPSIKDVDINEFARLIKVRCSTLQYFGSNISTQMEAITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCG3</accession>
    <name>A0A2H5VCG3_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00296</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74261">
        <property type="protein sequence ID" value="GBC74261"/>
        <property type="gene ID" value="HRbin05_00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="209"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="516" mass="59106" checksum="90BB16E08B5A2057" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCG5</accession>
    <name>A0A2H5VCG5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Short-chain-enoyl-CoA hydratase</fullName>
            <ecNumber evidence="2">4.2.1.150</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">crt</name>
        <name evidence="2" type="ORF">HRbin05_00426</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.150" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74386">
        <property type="protein sequence ID" value="GBC74386"/>
        <property type="gene ID" value="HRbin05_00426"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="271" mass="29536" checksum="F1A01B6D2A408538" modified="2018-02-28" version="1">MVYGNTMASSQPTNQQQQQQQYILVEKRDDGIAIVRINRQEKLNAMNLDVIAQLSSAMDNLASDEQVKAVIVTGTGEKAFSAGADIEYMSKISPLEAEEYARRGHAAMSKIENLNKPVIAAVNGYALGGGCELALACDIRIASKNAVLAQPEVGLGICPGWGGTQRLARIVGVARAKELIFTGRRVNAEEALSIGLVNKVVELPQLLDESIAMAKEIAKNSTLAVRVSKMLINRGVESDINTGLALELWGWSLCFTHPDRIERMNRFLQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCJ4</accession>
    <name>A0A2H5VCJ4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplE</name>
        <name evidence="4" type="synonym">rpl5</name>
        <name evidence="8" type="ORF">HRbin05_00329</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit; contacts the 5S rRNA and probably tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74291">
        <property type="protein sequence ID" value="GBC74291"/>
        <property type="gene ID" value="HRbin05_00329"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_A">
        <property type="entry name" value="Ribosomal_L5_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022804">
        <property type="entry name" value="Ribosomal_L5_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="6">
        <location>
            <begin position="8"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="7">
        <location>
            <begin position="65"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="173" mass="19319" checksum="2C0E5877BEF042D8" modified="2018-02-28" version="1">MSIMLEENVMRRIRIGKVVINAAVGKSGEPIEKAKKILEELTGHTPAVRTAKKTIRDFGIHKGEPIAVIVTLRKDKALQVLKRLLAAKGNRIKSSSFDDYGNVSFGIKEHIDIPGVKYKPELGIIGMDVCIALERPGYRVARRKIMPCKIGKEQRISRQEAIEFFKTLGVEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCK1</accession>
    <name>A0A2H5VCK1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gdhA</name>
        <name evidence="10" type="ORF">HRbin05_00430</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homohexamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74390">
        <property type="protein sequence ID" value="GBC74390"/>
        <property type="gene ID" value="HRbin05_00430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="9">
        <location>
            <begin position="182"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="7">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="417" mass="46048" checksum="B6FD1D5CC23D4AFC" modified="2018-02-28" version="1">MSDINPFENALKQLDEAARIMHLDEGMHEVLRTPKRVLTVSIPVRMDDGRVKVFIGHRVQHNDARGPYKGGIRYHPQVTLDEVKALAMWMTWKCAIVDVPFGGGKGGIACDPKSMSEHELERLSRRYAYMISDIIGPYVDIPAPDVYTGPREMAWIMDTYSALKGSISPGVITGKPLNIGGSKGRTEATGLGVAFCVREGAKKLNVDLKSARVVIQGFGNAGTYAAKFLKQMGASIIAVSDSKGGIFYDGKDGLDVEALIEHKTRTGMVRGFRNAREITNKELLELECDILVPAAYENQITKDNAENIKAKMVAEAANGPTTPEADEILFKKGKLVVPDILANAGGVTVSYFEWVQNLTRDYWSYEKVHDMLEGKMVTAFNDVYRTAEEYKVDMRKGSMVLAVNRVVDAIKARGIWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCK8</accession>
    <name>A0A2H5VCK8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00472</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74432">
        <property type="protein sequence ID" value="GBC74432"/>
        <property type="gene ID" value="HRbin05_00472"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="246" mass="27725" checksum="3110D3BEEFB5BEFB" modified="2018-02-28" version="1">MLSNKWLTIIGFTAIIITVTIIVSYNNKDKYLVTTDDVEVTDNLSLPHPYMIKKATLPPVKDIDEASTVVNHKLPYPKYLPKDYTIQYIGAINEGKDIWEVVIFAWDKEITDNTTNREFFYYGKGMVISISNNTKNSEAVIVDGVKEEGQEIGTALDELLAFYSKYGAHKLTIDGYQCVAYDSQIVEDAVGRKVPLLAEVDCLKDDLWIQIRAYLPESELVKVAESILQPFLMGTIPNSIKFLVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCL4</accession>
    <name>A0A2H5VCL4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="2">6.1.1.20</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pheT</name>
        <name evidence="2" type="ORF">HRbin05_00467</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74427">
        <property type="protein sequence ID" value="GBC74427"/>
        <property type="gene ID" value="HRbin05_00467"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B3_4" evidence="1">
        <location>
            <begin position="69"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="219" mass="24559" checksum="5BB4D8229E1AFE2B" modified="2018-02-28" version="1">MSIDGSDHTSMVSIHIAEEVRDYRVSLYAKAMDVKVRHDHDYSNVMDELKARLTLSKDDLKNHPVVRALRDFYWRLGIDPTKVRPSSEALARRFLMGKMPRINNVVDAGNIASIETLVPIGIYDLAMVKGRLVLRRAISNEEFIDITGKASRLTGKEIVLADEQGVIHVFPHRDALRTSVKDDTSRILVVGCYIMDGMDASLARVAVDRTIELIKASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCL6</accession>
    <name>A0A2H5VCL6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="3">6.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">acsA_2</name>
        <name evidence="3" type="ORF">HRbin05_00482</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74442">
        <property type="protein sequence ID" value="GBC74442"/>
        <property type="gene ID" value="HRbin05_00482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="2">
        <location>
            <begin position="21"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="76"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="403" mass="45847" checksum="2051B69854D8730E" modified="2018-02-28" version="1">MLAGSSKITKGTSDGRLLMQLRDRAARDPEGFWAEQATLLEWFKVWDMVLDWKPPFARWFINGLINASYNALDRHLPSKGDKVAIHWQGEQDDERRSITYREMHREVNRVANALKDLGLKRGDRVAIYMPMVPELPIAMLACVRIGAIHSVVFSGFSAGALADRINDSNARLVITADGYHRRGKVINLMENVASALNACKSVEHVIMLNRLGIYGNNGKSNSSIGNASYIDWHDMVDRYDGYCEPERVESNEPLFILYTSGTTGKPKGIVHSTGGYLTYANATFRWIFGIRDEDVYFCTADIGWVTGHSYVVYAPMMNATTIIMYEGTPDYPTVHRWFELIERFRATIFYTTPTALRMLMRYNIEYAKVHDLSSLRLLGTVGEPINPEVWLWYYRAIGERGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCL7</accession>
    <name>A0A2H5VCL7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">S-adenosylmethionine decarboxylase proenzyme</fullName>
            <shortName evidence="10">AdoMetDC</shortName>
            <shortName evidence="10">SAMDC</shortName>
            <ecNumber evidence="10">4.1.1.50</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="10">S-adenosylmethionine decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="10">S-adenosylmethionine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">speH</name>
        <name evidence="11" type="ORF">HRbin05_00479</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>H(+) + S-adenosyl-L-methionine = CO2 + S-adenosyl 3-(methylsulfanyl)propylamine</text>
            <dbReference type="Rhea" id="RHEA:15981"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="4.1.1.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="10">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amine and polyamine biosynthesis; S-adenosylmethioninamine biosynthesis; S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.</text>
    </comment>
    <comment type="PTM">
        <text evidence="10">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.50" evidence="10"/>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74439">
        <property type="protein sequence ID" value="GBC74439"/>
        <property type="gene ID" value="HRbin05_00479"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00331">
        <property type="reaction ID" value="UER00451"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006557">
        <property type="term" value="P:S-adenosylmethioninamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.360.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00464">
        <property type="entry name" value="AdoMetDC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042286">
        <property type="entry name" value="AdoMetDC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042284">
        <property type="entry name" value="AdoMetDC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017716">
        <property type="entry name" value="S-AdoMet_deCOase_pro-enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33866">
        <property type="entry name" value="PTHR33866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="SSF56276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03330">
        <property type="entry name" value="SAM_DCase_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 10" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="2 10" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 10" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 10" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="8 10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="4 10" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023503162" description="S-adenosylmethionine decarboxylase beta chain" evidence="10">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023503161" description="S-adenosylmethionine decarboxylase alpha chain" evidence="10">
        <location>
            <begin position="63"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="10">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; for processing activity" evidence="10">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor; for catalytic activity" evidence="10">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autolysis" evidence="10">
        <location>
            <begin position="62"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="10">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="122" mass="13944" checksum="99D67D01F76E70EB" modified="2018-02-28" version="1">MGALGYNIFADMYGCDASILNDVEYLRAVMKEAARKGNMSVVRTIFHRYEPHGVTGVVIVKESHLAIHTWPEYSFASVDIFLCGTNSNPYEALKYIELKLRPKKVYTNSMERGMAIEYERIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCL9</accession>
    <name>A0A2H5VCL9_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74435">
        <property type="protein sequence ID" value="GBC74435"/>
        <property type="gene ID" value="HRbin05_00475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="94" mass="10704" checksum="79195D2C65EC14EE" modified="2018-02-28" version="1">MFYGYSLDSQHYHIADSYLVINSSDSYTTLVIEPDYIDDMEIYKHLSVTADNYYIDIPASKGDNILHTVQLRVSASNDARGSLYIQSRGCKLGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCM2</accession>
    <name>A0A2H5VCM2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Polyamine aminopropyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Putrescine aminopropyltransferase</fullName>
            <shortName evidence="2">PAPT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Spermidine synthase</fullName>
            <shortName evidence="2">SPDS</shortName>
            <shortName evidence="2">SPDSY</shortName>
            <ecNumber evidence="2">2.5.1.16</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">speE</name>
        <name evidence="5" type="ORF">HRbin05_00478</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>putrescine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + S-methyl-5'-thioadenosine + spermidine</text>
            <dbReference type="Rhea" id="RHEA:12721"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="2.5.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer or homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74438">
        <property type="protein sequence ID" value="GBC74438"/>
        <property type="gene ID" value="HRbin05_00478"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00248">
        <property type="reaction ID" value="UER00314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030373">
        <property type="entry name" value="PABS_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="PTHR11558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01330">
        <property type="entry name" value="PABS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="4">
        <location>
            <begin position="6"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-methyl-5'-thioadenosine binding" evidence="2">
        <location>
            <begin position="142"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2 3">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="309" mass="35331" checksum="BD573B4CB45CA689" modified="2018-02-28" version="1">MSESNEQWVVEETYPGFKVSHKVKRRILAKRTKWQYIELVDTMNFGKMLIIDGLIQSSERDEHYYHEAIVHPAMVTHREPKDVLILGGGEGACLREVLKHNTVRSVVMVDIDEDMISLSKEYLASMHNDSYNDARVLLLIEDAKEYVQRCSKAGKQFDVIIQDLTDPQQDSPSRMLYTLEYFNTINGILSSDGIFVTQATLLHPSAKAYAIIHNTLRHVFPVVRGYATYISCYANLSGFILASKMYDPLLISKEEVEERLRARGIDIRSLKHYDGEAHHAYFALPKYIRDGIAMVKDTSTIDNPVVFPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCM4</accession>
    <name>A0A2H5VCM4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00477</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74437">
        <property type="protein sequence ID" value="GBC74437"/>
        <property type="gene ID" value="HRbin05_00477"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="64" mass="7268" checksum="B0A537C86DAD0A0F" modified="2018-02-28" version="1">MVWVYVVIGLLIILVLVVLLKGERRPLYGKYHATDTLTICLSCGSRFRGSKCPYCGFEHAEHKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCM7</accession>
    <name>A0A2H5VCM7_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00359</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000012">
        <property type="protein sequence ID" value="GBC74321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74321">
        <property type="protein sequence ID" value="GBC74321"/>
        <property type="gene ID" value="HRbin05_00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019151">
        <property type="entry name" value="Proteasome_assmbl_chaperone_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038389">
        <property type="entry name" value="PSMG2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09754">
        <property type="entry name" value="PAC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="249" mass="28475" checksum="C824869C8B8157F7" modified="2018-02-28" version="1">MLGTKVHYYPRLDKPVMVAALPDMGNVAGLCISTLLKGLNAELFAEVYAYWPPYVTYKDGVVEYRQSTYRFYYSSRDDLVIFGGDFNPTDPRRLYEVCYEVVNMAQRLSVKRLYTLGAALRPSVGAEPRVYGAVNNSSLIDVLREHNILILEGEGQITGFNGLILGIAMERGLDAICILGEIDNPEIIQPRSAKRVLEKMLEISKIRGFDMSELDEEERRKRFMEEQLRYMNSMLERNKGKGRDIGIYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCP4</accession>
    <name>A0A2H5VCP4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74430">
        <property type="protein sequence ID" value="GBC74430"/>
        <property type="gene ID" value="HRbin05_00470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="76" mass="8303" checksum="E2BA27667796D3C7" modified="2018-02-28" version="1">MGMVPSALLQHLKTVPEIILTYLQHDNHPHIAVQLVAPYTIIMLGAMLDTISTDAVITAIAILDAIGFIIKKVKQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCQ4</accession>
    <name>A0A2H5VCQ4_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="8">PCK</shortName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="4 8">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">pckA</name>
        <name evidence="9" type="ORF">HRbin05_00509</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4 8"/>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74468">
        <property type="protein sequence ID" value="GBC74468"/>
        <property type="gene ID" value="HRbin05_00509"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="318"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="437"/>
            <end position="438"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="529" mass="58916" checksum="C0B69B3D34CED814" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCR1</accession>
    <name>A0A2H5VCR1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PUA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00527</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000022">
        <property type="protein sequence ID" value="GBC74486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74486">
        <property type="protein sequence ID" value="GBC74486"/>
        <property type="gene ID" value="HRbin05_00527"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016437">
        <property type="entry name" value="MCT-1/Tma20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22798">
        <property type="entry name" value="PTHR22798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005067">
        <property type="entry name" value="Tma_RNA-bind_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PUA" evidence="1">
        <location>
            <begin position="80"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="167" mass="18566" checksum="B67FF90D16FB8426" modified="2018-02-28" version="1">MREYHLSKSDIDVIMQRIRDGWPRHVSTGIKKPKSLKIIEMDDGSIDDNSILVGEGMILVIKDGMILPFLTMNSLLALFPSVTVDMGAVKHVCNGADVMRPGIVSMDEFDKGGIVGVNDERYGKYIAVGIATVSSNDARAMSKGVVVYNKHYIGDRFWEECKRRSIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCR8</accession>
    <name>A0A2H5VCR8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000022">
        <property type="protein sequence ID" value="GBC74489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74489">
        <property type="protein sequence ID" value="GBC74489"/>
        <property type="gene ID" value="HRbin05_00530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="SSF50974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="716" mass="77852" checksum="8C0190B0486A86AC" modified="2018-02-28" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCS2</accession>
    <name>A0A2H5VCS2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Proteasome subunit beta</fullName>
            <ecNumber evidence="9">3.4.25.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">20S proteasome beta subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Proteasome core protein PsmB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">prcB_2</name>
        <name evidence="9" type="synonym">psmB</name>
        <name evidence="10" type="ORF">HRbin05_00528</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="9">Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Cleavage of peptide bonds with very broad specificity.</text>
            <dbReference type="EC" id="3.4.25.1"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the peptidase T1B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.25.1" evidence="9"/>
    <dbReference type="EMBL" id="BEHH01000022">
        <property type="protein sequence ID" value="GBC74487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74487">
        <property type="protein sequence ID" value="GBC74487"/>
        <property type="gene ID" value="HRbin05_00528"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019774">
        <property type="term" value="C:proteasome core complex, beta-subunit complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004298">
        <property type="term" value="F:threonine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010498">
        <property type="term" value="P:proteasomal protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02113_A">
        <property type="entry name" value="Proteasome_B_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019983">
        <property type="entry name" value="Pept_T1A_Psome_bsu_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000243">
        <property type="entry name" value="Pept_T1A_subB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016050">
        <property type="entry name" value="Proteasome_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001353">
        <property type="entry name" value="Proteasome_sua/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023333">
        <property type="entry name" value="Proteasome_suB-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00227">
        <property type="entry name" value="Proteasome"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00141">
        <property type="entry name" value="PROTEASOME"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00854">
        <property type="entry name" value="PROTEASOME_BETA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51476">
        <property type="entry name" value="PROTEASOME_BETA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 9" id="KW-0645">Protease</keyword>
    <keyword evidence="7 9 10" id="KW-0647">Proteasome</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0888">Threonine protease</keyword>
    <keyword evidence="8 9" id="KW-0865">Zymogen</keyword>
    <feature type="propeptide" id="PRO_5014202565" description="Removed in mature form; by autocatalysis" evidence="9">
        <location>
            <begin position="1"/>
            <end position="9"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023519134" description="Proteasome subunit beta" evidence="9">
        <location>
            <begin position="10"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="GBC74487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="205" mass="22169" checksum="B55C6E13E81DEE70" modified="2018-02-28" version="1">MAFEQFMPGATAVGIAFADGVVLAAEKRVSFGTYVVSRSGKKVFKITERVGAACAGMVADMQILMRQVESIARLKSFEIRREVPPNSIGKLVSVLLFERRYFPLLTQIIIGGIDVYTEKPAIYTLDPLGSILPDDYAAVGTGAEMAIGVIESAYRPDMNEQEARDLTLKAIRAAVARDAASGDGVDMLIITKNGCKEESLMLKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCS3</accession>
    <name>A0A2H5VCS3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine/threonine-protein kinase PknD</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pknD</name>
        <name evidence="3" type="ORF">HRbin05_00529</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000022">
        <property type="protein sequence ID" value="GBC74488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74488">
        <property type="protein sequence ID" value="GBC74488"/>
        <property type="gene ID" value="HRbin05_00529"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="412"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="435" mass="47748" checksum="425C46D8398945BE" modified="2018-02-28" version="1">MQPSPFLLIIVMLVSISIVDAYAENRYNINLLKILTGYNDSDGMFNTPYGAVIDSNGRIIVTDNLNNRIQVFDSNGNFLFKFGIPGYDPGGFTHPSGVTVNSNGDIIVADLHNYRVQVFDRNGVYKFQFGKPSSYDGQFTYPISVAVDSKDRIIVTDTYMHRIQVFDSNGNFLFKFGKEGSGDGEFSFPTGVAVDSKDRIIVADVWNNRIQVFDSNGNFLFKFGKEGSGDGEFMFPNGVAVDGYGNIIVADTFNNRIQVFDSNGNFLFKFGKEGSGDGEFSFPTGVAVRDDMLVVVDTGNNRVQVFKISSTEGIELGRDEGKPSLQLLNGTVDVGQSIRAVVHSSMNTARFIWIGPDGSIVREVTKDISNGKAEDEFIPSMEGVWNVEVELSNGSNVERLNATARVIPEFPLAPPILAGLIAMILLFTARLGRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCS9</accession>
    <name>A0A2H5VCS9_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 10">Shikimate kinase</fullName>
            <shortName evidence="10">SK</shortName>
            <ecNumber evidence="5 10">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">thrB_3</name>
        <name evidence="10" type="synonym">aroK</name>
        <name evidence="13" type="ORF">HRbin05_00544</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the GHMP kinase family. Archaeal shikimate kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="5 10"/>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74503">
        <property type="protein sequence ID" value="GBC74503"/>
        <property type="gene ID" value="HRbin05_00544"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00370">
        <property type="entry name" value="Shik_kinase_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010189">
        <property type="entry name" value="SK_arc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20861:SF3">
        <property type="entry name" value="PTHR20861:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005758">
        <property type="entry name" value="Shikimt_kin_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01920">
        <property type="entry name" value="Shik_kin_archae"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="11">
        <location>
            <begin position="88"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="12">
        <location>
            <begin position="258"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="95"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="GBC74503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="315" mass="34129" checksum="DB2646CC98593A27" modified="2018-02-28" version="1">MLVMGMDRDTNSNTRIAMVNMHGAISIVNAIPTGKGSTLGIGLGVNVTVRMSSGQGRIVSNTGDVGFIHNIIKRIMPDDMLKHKDIAIEIRSRIPMGYGLKSSSAVSNAIALACHRLVVNDDNYGDEDNHDGARDWITARDLKVIDAAVSASIESRVSITGAFDDACACYFGGIFVTDNHARRILKHERVDENVNVVILLPMGIRRSDPMRLRHPLLVEHFNHAIRLAEDGRYWDAMILNGVLVSSLLSIPYNLVLDALEHGALAAGISGNGPAVTAITDSESKAKDIAYVWQNYGEVIRSKASNEKAVVSMVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCV1</accession>
    <name>A0A2H5VCV1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sec-independent protein translocase protein TatA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tatA_2</name>
        <name evidence="8" type="ORF">HRbin05_00431</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000016">
        <property type="protein sequence ID" value="GBC74391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74391">
        <property type="protein sequence ID" value="GBC74391"/>
        <property type="gene ID" value="HRbin05_00431"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="111" mass="12213" checksum="755B1CC32276D7E6" modified="2018-02-28" version="1">MINIGGSEWIIIVLLFLILIVGSKHLPSLGRSIGKAVGEYERARASIRRELDRMNANTNTNTSIGLTIPIKGPVSSEREKLEAVARALGIDPNGVSDDELRRLLHERLNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCY0</accession>
    <name>A0A2H5VCY0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nadK_2</name>
        <name evidence="5" type="synonym">nadK</name>
        <name evidence="6" type="ORF">HRbin05_00595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74553">
        <property type="protein sequence ID" value="GBC74553"/>
        <property type="gene ID" value="HRbin05_00595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="68"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="141"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="181"/>
            <end position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="271" mass="30069" checksum="EBFD4AAE8E490DAE" modified="2018-02-28" version="1">MQIRSVLITARYGSARASELASSIVGMIHDKGCSIYTVNPIKVEGTREVDESMIKALDIDLAIAIGGDGTVLRTVRWLSTKHVPVLAIKLPTSKGMLAEVTAERSDIEHAIHRLFSNSFYVERRMRIMASVDGRELQPALNEMLIIRDNLTRTPTYRMRLVGTEIAYRMDGLIVSTPTGSTGHSLSFGGSIVYEGLEAMMITPIAPINRMPSIVIPVTDVEVRSNMDAKVVIDGQVVYDVRQDQVISIGRYEHDALFIRFEPRGLRQLANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCY4</accession>
    <name>A0A2H5VCY4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74544">
        <property type="protein sequence ID" value="GBC74544"/>
        <property type="gene ID" value="HRbin05_00586"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="195" mass="21635" checksum="BA91BA61433A765A" modified="2018-02-28" version="1">MDELLRWTREVFMPIGDVGLFILAFLESSVFPVPPDVLLIALALANPALALYYATIATIGSVLGGVAGYYIGLKGGRRVAKRIFSERMIERADNYFKEYGVWAVLIAAFSPIPYKVFTIASGIFRLSLKGFIIASIIGRGARFYVEGLLIMLWGEQILAFVDENLELISLAIAGAIISYLVLRKRLAREKKRRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCZ6</accession>
    <name>A0A2H5VCZ6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DDE_Tnp_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00609</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000029">
        <property type="protein sequence ID" value="GBC74567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74567">
        <property type="protein sequence ID" value="GBC74567"/>
        <property type="gene ID" value="HRbin05_00609"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="109"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="293" mass="34579" checksum="6DFA9B234D9F2194" modified="2018-02-28" version="1">MNWHEVDERLIKRGEILVSLDFVKNYDKELEEMNKGKVGRPYQITNSYAQFLALIRYMLDIPYKQLEGFTIALNRLIPELKPVDYSEIRKRLIKLDYKLDIKNNDDEPLIISLDSTGSKVHKSYGWIERKHGKKKHYIKIHFAINVKTKEIIDMRITNDDIADSKAALDMLKDIVKDNKIKIDKIYADGAYDNISLYKLLEDNGIKDIVIKPRRNARDDSISNIRNENIKCIKQFGYKQWSKLKGYGKRWIVETVFSTFKRLFNEYCLSTSINGIIKELKTKVWIYNMLVRMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD00</accession>
    <name>A0A2H5VD00_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00471</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000018">
        <property type="protein sequence ID" value="GBC74431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74431">
        <property type="protein sequence ID" value="GBC74431"/>
        <property type="gene ID" value="HRbin05_00471"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="166" mass="18893" checksum="7FA57E59F8FC4DEE" modified="2018-02-28" version="1">MVGYMVSPLWVILGNGRLLEICWIASASYTPKWYWALDGIMQKTWCTNNTCPSNNSTWLFTIHDGNADQVWILRVGTDTITTERLGSTLSTETEAGYEIGYYDTNPGINEYKDFMYYKPNTGWVYISSSAASQWYYINPVNGYTVDYCNNAYNHFMVAKGGGRNLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD01</accession>
    <name>A0A2H5VD01_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HRbin05_00610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000029">
        <property type="protein sequence ID" value="GBC74568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74568">
        <property type="protein sequence ID" value="GBC74568"/>
        <property type="gene ID" value="HRbin05_00610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011639">
        <property type="entry name" value="RM_methylase_Eco57I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07669">
        <property type="entry name" value="Eco57I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Eco57I" evidence="3">
        <location>
            <begin position="47"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="352" mass="41736" checksum="A571D61EC17C350C" modified="2018-02-28" version="1">MNKINELFIDKLDRKFAEEHKLSELKKVKTFHWVFEFPEVMLDKGGFDVVIGNPPYVRQEMINHLVDEIDYKGILSKFYKPFDNTFDYSMFFILRSLQITKSKGYHSFIITNKWLRAEYGKKIREFLKENFTIKKVIDFNGIKVFVGATVDTMVYVIQKDKPTKNEILYNHPSDLTKIEEGAYYVKQESLNNEVWSFVNKDLEEIKEYIENVGRPLKELDVKIYSGIKTGFNEAFIIDDETRQKIIRDDPKSAELIKPVLRGDDIERYYVKWDKHWIIVIPSGITRTLAKEYKLKEKSQLEEIIFKQVYPSVYNHLKQFVSINSNKSALWINYNISLTIQYLIIYTFSFIPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD07</accession>
    <name>A0A2H5VD07_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-aspartate dehydrogenase</fullName>
            <ecNumber evidence="6">1.4.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">nadX</name>
        <name evidence="9" type="ORF">HRbin05_00616</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + L-aspartate + NAD(+) = H(+) + NADH + NH4(+) + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:11788"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.4.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + L-aspartate + NADP(+) = H(+) + NADPH + NH4(+) + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:11784"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; NAD(+) biosynthesis; iminoaspartate from L-aspartate (dehydrogenase route): step 1/1.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the L-aspartate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.21" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74574">
        <property type="protein sequence ID" value="GBC74574"/>
        <property type="gene ID" value="HRbin05_00616"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00456"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033735">
        <property type="term" value="F:aspartate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01265">
        <property type="entry name" value="NadX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002811">
        <property type="entry name" value="Asp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022487">
        <property type="entry name" value="Asp_DH_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020626">
        <property type="entry name" value="Asp_DH_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011182">
        <property type="entry name" value="L-Asp_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01958">
        <property type="entry name" value="DUF108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005227">
        <property type="entry name" value="Asp_dh_NAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03855">
        <property type="entry name" value="NAD_NadX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="4 6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_binding_3" evidence="8">
        <location>
            <begin position="15"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DUF108" evidence="7">
        <location>
            <begin position="177"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="279" mass="30357" checksum="A1E7804EE217A306" modified="2018-02-28" version="1">MESRKGEKRKVGLIGCGAIGSEIAVAIDSSRVNAELIAVYDACRERAYTLVSRLNKRPMIADSIEALLASDTELIVEAASQQAVKDYARSIVEHGNDIMLMSVGALLDDTFYAELCSLLERHGRRLYLPTGAIAGIDAIRSVKHMLKEVTLTTTKHPRALVGAPFFKEHRVNLKGLKKARVIYNGYAREAVRLFPANVNVAAILSIAGIGADKTKVKIVADPRARRNIHEIHAKGEFGELYFKVSNVPSPSNPKTSYLAVLSAIECLSRACNGRVSIGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD09</accession>
    <name>A0A2H5VD09_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Benzene 1,2-dioxygenase system ferredoxin subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">bnzC</name>
        <name evidence="5" type="ORF">HRbin05_00630</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000031">
        <property type="protein sequence ID" value="GBC74586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74586">
        <property type="protein sequence ID" value="GBC74586"/>
        <property type="gene ID" value="HRbin05_00630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="102" mass="11416" checksum="5AE2C5BE3DBA7D03" modified="2018-02-28" version="1">MGRVLACRRDELPNGKMKYLQIDGNDILLANVDGAYYAVSDICNHAGANLHEGKINGKYITCPWHKAVWDVTNGELVQFPVRLRPLKVYKVIVDGDAVYVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD14</accession>
    <name>A0A2H5VD14_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Exosome complex component Rrp42</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rph</name>
        <name evidence="2" type="synonym">rrp42</name>
        <name evidence="5" type="ORF">HRbin05_00602</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the archaeal exosome complex. Forms a hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers. The hexameric ring associates with a trimer of Rrp4 and/or Csl4 subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RNase PH family. Rrp42 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000028">
        <property type="protein sequence ID" value="GBC74560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74560">
        <property type="protein sequence ID" value="GBC74560"/>
        <property type="gene ID" value="HRbin05_00602"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000178">
        <property type="term" value="C:exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11365">
        <property type="entry name" value="RNase_PH_archRRP42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00622">
        <property type="entry name" value="Exosome_Rrp42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020869">
        <property type="entry name" value="Rrp42_archaea"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0271">Exosome</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNase_PH" evidence="3">
        <location>
            <begin position="36"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="4">
        <location>
            <begin position="193"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="280" mass="30343" checksum="3C5B3018E494C7E0" modified="2018-02-28" version="1">MSVKKTTTIVEQLRRAQMSELLAMSKRLDGRGLRDYRELRIDVGLIKKANGSALVSLGNTQVIAGIKVEVDEPFPDMPDKGLFICNAEVLPLASPYAEPGPPDEDAIELARVVDRGIRESEMIALDKLVLISGKKVYAVFADVSVLNSDGNLFDATSYAVVAALLTARIPKYDVQDDKLVKSEETIPLPINTIPVSVTMAKIGNSIIVDPTAEEEACMDARITMATDEHGRVCAIQKGGSGTFSLEQLSEVATLAISIGKEMREKIGNVAARAREQEQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD16</accession>
    <name>A0A2H5VD16_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-coenzyme A synthetase</fullName>
            <ecNumber evidence="3">6.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">acsA_1</name>
        <name evidence="3" type="ORF">HRbin05_00481</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000019">
        <property type="protein sequence ID" value="GBC74441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74441">
        <property type="protein sequence ID" value="GBC74441"/>
        <property type="gene ID" value="HRbin05_00481"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="2">
        <location>
            <begin position="99"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="221" mass="24562" checksum="995E1497D73C5810" modified="2018-02-28" version="1">MKPGSASLPLPGIDAAVVDDDGNEVRGKKGYLIVKRPWPGLMLTIWGDDERYKQTYWSRFRNAYYPADYAMVDDDGYFWLLGRADEVLKVAGHRLGTMEVESAIVAHPAVAEAAVVGKVDQIKGESIVAFVVPKQGYAEYSELRHSIIKQVESSLGAIARPEQIYFVSKLPKTRSGKIMRRLLKAIVNDAQIGDTTTLDDEAAIDEVKAVYEELRKKITSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD25</accession>
    <name>A0A2H5VD25_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Transcription elongation factor Spt4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">spt4</name>
        <name evidence="4" type="ORF">HRbin05_00612</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Stimulates transcription elongation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer composed of Spt4 and Spt5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal Spt4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000030">
        <property type="protein sequence ID" value="GBC74570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74570">
        <property type="protein sequence ID" value="GBC74570"/>
        <property type="gene ID" value="HRbin05_00612"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00949">
        <property type="entry name" value="Spt4_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022800">
        <property type="entry name" value="Spt4/RpoE2_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007178">
        <property type="entry name" value="Spt4_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038589">
        <property type="entry name" value="Spt4_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40704">
        <property type="entry name" value="PTHR40704"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06093">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01389">
        <property type="entry name" value="Spt4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="SSF63393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Spt4" evidence="3">
        <location>
            <begin position="3"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="GBC74570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="61" mass="6836" checksum="F30C8E68F6D049E2" modified="2018-02-28" version="1">MKEYACRRCKAITTGKVCPVCKSADLSADWYGLVLIVNPEESRIARLLNITQKGKYAMKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD31</accession>
    <name>A0A2H5VD31_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase Pat</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00643</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000033">
        <property type="protein sequence ID" value="GBC74599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74599">
        <property type="protein sequence ID" value="GBC74599"/>
        <property type="gene ID" value="HRbin05_00643"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="144" mass="16419" checksum="47258CF7A6E48F73" modified="2018-02-28" version="1">MFRHLSQESVYQRFFTVIKDTPHEQIVRYCNIDYAREMSIVAELSEGSMRRIIGVASLVIDGRRSRDGYREGEIAVIVADPWQGLGLGTKLVDYILEIAEDMNVKVVNAVMLANNARIIDLMKRMGFRLEVLDEDTLIGRLELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD41</accession>
    <name>A0A2H5VD41_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Probable tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="2">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="2">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">truB</name>
        <name evidence="6" type="ORF">HRbin05_00658</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2">Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the pseudouridine synthase TruB family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74614">
        <property type="protein sequence ID" value="GBC74614"/>
        <property type="gene ID" value="HRbin05_00658"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01081">
        <property type="entry name" value="TruB_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012960">
        <property type="entry name" value="Dyskerin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004802">
        <property type="entry name" value="tRNA_PsdUridine_synth_B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026326">
        <property type="entry name" value="TruB_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004521">
        <property type="entry name" value="Uncharacterised_CHP00451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23127">
        <property type="entry name" value="PTHR23127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08068">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01136">
        <property type="entry name" value="DKCLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00425">
        <property type="entry name" value="CBF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00451">
        <property type="entry name" value="unchar_dom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DKCLD" evidence="5">
        <location>
            <begin position="9"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="PUA" evidence="4">
        <location>
            <begin position="244"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="344" mass="38256" checksum="6211BB45371F90E2" modified="2018-02-28" version="1">MICNSKLPQLNDLLSIDDDVTDEHYGYHPFSRPIDVLLDYGLIALDKPAGPTSHEVVAWVKRILAVESAGHSGTLDPPTTGLLPIGLGEATKALTVLLLGPKEYYAIARLHAVVPSKMLHDVVSMFIGDIYQRPPQRSSVKREVRVRRIYELEVLEEHGRLLLLRVLCQAGTYVRKLIYDIGEVLGYGASMVELRRTRVSILDEDDMVRLHDLYDAYMLWREKGEEEKLRSIIKPIEYALMHVKAVVVRDSAVDSICHGAQLAVPGVLKVSKDLQKGDLVGIYTLKGELVALAEAMMSAHEIAEADKGIAFTLKRVIMKPNTYPKAWKSKSSSSSNSSSRSEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD45</accession>
    <name>A0A2H5VD45_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Adenylate kinase</fullName>
            <shortName evidence="8">AK</shortName>
            <ecNumber evidence="3 8">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7 8">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">adkA</name>
        <name evidence="9" type="ORF">HRbin05_00661</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the archaeal adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="3 8"/>
    <dbReference type="EMBL" id="BEHH01000034">
        <property type="protein sequence ID" value="GBC74617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74617">
        <property type="protein sequence ID" value="GBC74617"/>
        <property type="gene ID" value="HRbin05_00661"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00234">
        <property type="entry name" value="Adenylate_kinase_AdkA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023477">
        <property type="entry name" value="Adenylate_kinase_AdkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="19"/>
            <end position="27"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="GBC74617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="204" mass="22964" checksum="1FA074AEDE8E8378" modified="2018-02-28" version="1">MRSLEGSSIINNKRAIVVGIPGVGKTTVITRAVEMLNTQGLNARLVVFGTVMFEEAMKMGVKHRDEMRRLSVEEQRRLQENAAVKIANMKDDVIIIDTHLFISTKEGYYPGLPLHLLNLLKPTNLILVAAEPREILNRRMNDKTRQRDLVDEAEIAHELEIARIMLASCSILTGAPFAIVMNREGRVDEASHELANLLTDRRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD66</accession>
    <name>A0A2H5VD66_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00673</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000035">
        <property type="protein sequence ID" value="GBC74629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74629">
        <property type="protein sequence ID" value="GBC74629"/>
        <property type="gene ID" value="HRbin05_00673"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="253" mass="27915" checksum="F9DEC8FA02EA5178" modified="2018-02-28" version="1">MEWKVSKNPLGMLEVVMDREEVITAEPGALVYMQGDVEVKTSTKIKEQGLLSRVKSTILGGESFFLNDYIANGRCMLGFAGPMIGDIEGIHVDGSYIVQSRAYLASIGNLSLDTKFQGMVKGLFGTELFMLKVDGNGLVFVNTYGSLFKKELKDGERIVVDNYHLVAMNATAEYKVVKIGGMKTLLLGGEGLGIDVTGPATLYIQSRNMLELKAELTRLLELEKYKGAQFNVGIGAGKEEKDRQRWGWDMPRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD73</accession>
    <name>A0A2H5VD73_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease V</fullName>
            <ecNumber evidence="2">3.1.21.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nfi</name>
        <name evidence="2" type="ORF">HRbin05_00683</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.</text>
            <dbReference type="EC" id="3.1.21.7"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.7" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000036">
        <property type="protein sequence ID" value="GBC74639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74639">
        <property type="protein sequence ID" value="GBC74639"/>
        <property type="gene ID" value="HRbin05_00683"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043737">
        <property type="term" value="F:deoxyribonuclease V activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007581">
        <property type="entry name" value="Endonuclease-V"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28511">
        <property type="entry name" value="PTHR28511"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04493">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="210" mass="22587" checksum="D952E7291AFE3747" modified="2018-02-28" version="1">MAFAAAVMVDRLDGKIVYESNSISRVYIPYIPGLLFLREGAPMLSALRSLIKHVYGRSCIGCIDDCIVIVDGNGMLHPRLFGLACYIGILIDIPTVGVSKSLLCGTIISKGSDGCVMLNGREVARVVEYNGKRIYVSIGHKISLDSAEGIVRSLIHYGEETGAEGVRARARKSKSIPLSSSSLPSSLPLPEPLRLAHNAANALRRSQALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD79</accession>
    <name>A0A2H5VD79_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00682</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000036">
        <property type="protein sequence ID" value="GBC74638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74638">
        <property type="protein sequence ID" value="GBC74638"/>
        <property type="gene ID" value="HRbin05_00682"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="493" mass="55616" checksum="5FF2E7DB34214837" modified="2018-02-28" version="1">MHSNGYDYDIIVAGAGIAGTIAAISAAKHNNSMRILLIDKNPEYEAGKKTLNGWVCGDAVGKNNVDYLAKHTGLRWDRPEIEHDVKGVVAYSPDHETPIYFEGDGYILNRRLLPFKQIEYAKKLGVEFRWNVMLRQVIAEDGYVKGVQGIDLSSNQPFKARARVVIDCTGIASMLRSTLPIHTYIQRSIDKDDIEATGRYILTFDPAKEDRTYFDPDYAIIHLNQIIAPGGYAWVFPKSDRKVNIGLGVQHRSLELRNAMLKRSDTLKSLIDAYVASNPVISNPRLADGKDDDGNAWGTWQVSVRRQNDCLVANGYMLAGDSAWMPKPLDAGGIGPAIIAGVIAGRDAVYAIESNDVSEHGLWRYNVDFVDEYGYKTAGLEVFRRFLQTLSNEQINYGMKHFISKLDVEKISKGEHPDFGYVDKISMLIRGVLHRRTAEGLKYTADVNRVLVEHYRNYPRSPDGFREWHKRLMTILNDAFARFNVRPEIYAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD85</accession>
    <name>A0A2H5VD85_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle 19 kDa protein</fullName>
            <shortName evidence="5">SRP19</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">srp19</name>
        <name evidence="6" type="ORF">HRbin05_00700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. Archaeal SRP consists of a 7S RNA molecule of 300 nucleotides and two protein subunits: SRP54 and SRP19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SRP19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74655">
        <property type="protein sequence ID" value="GBC74655"/>
        <property type="gene ID" value="HRbin05_00700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.56.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00305">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002778">
        <property type="entry name" value="Signal_recog_particle_SRP19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036521">
        <property type="entry name" value="SRP19-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022938">
        <property type="entry name" value="SRP19_arc-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01922">
        <property type="entry name" value="SRP19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69695">
        <property type="entry name" value="SSF69695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0733">Signal recognition particle</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="101" mass="11818" checksum="DC91E56EFB6A5FA7" modified="2018-02-28" version="1">MKDYEHHIIWLDYFNKNLSKGKGRRINKSKAVFDPSMDELVEAARLAGYEPKDVNDNARYPRRSYTRSGYIMVEKKEGINKSTVLNRIAEALLQIRSRRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD88</accession>
    <name>A0A2H5VD88_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00563</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000025">
        <property type="protein sequence ID" value="GBC74521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74521">
        <property type="protein sequence ID" value="GBC74521"/>
        <property type="gene ID" value="HRbin05_00563"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="351" mass="37946" checksum="FD6B0428869CFAFA" modified="2018-02-28" version="1">MKYVSLAIVGIVIMMLTMPTLYAQGQIPQIPSIKEVSGRYVNDNAGIEITFPAGWSGMEMPLIMGMGNTIAMAVVMPGGIKDPSSVSPTGPMIMLNVTVIEKATLPSIKDTQFGKSDERVKEPECKLLSFSNKSVNGVNGIVVEVECEVEFDGKPVTMRAKLFNASQEKDNTIRSVMLLLASTVDKYSSYVGDFDKALDTLRISNARSMDISQSISKDFTQEVSVDGQNIPLNIYSNSDVKNLRFDAGSKTISFNVEGEGGSLGITDIYPNNILKGPYIVTIDGEPAITMQITKPDSGEEGIRILYTHSIHEIKVVGTEVIPEFPIAVLPILALITGIAVFMARGKGMYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD89</accession>
    <name>A0A2H5VD89_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00693</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000038">
        <property type="protein sequence ID" value="GBC74648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74648">
        <property type="protein sequence ID" value="GBC74648"/>
        <property type="gene ID" value="HRbin05_00693"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="182" mass="20454" checksum="8FA0184988CCE631" modified="2018-02-28" version="1">MGTRTNIIIAGVAISIAAYLILSFFTSTGIFEKKMGVYHAEIDMSIEEISRWADIIVIGRVGDRVGVQSHDDGKIYKVVGELTLDIEQELTGNYNDKVIVLKTVGDGEKVINMNVSLKKGERVLLFLNYVTTDQQWKGEEGYLVCCTQQKFSIDENNIAYNPKYGSYKLDELIEMIKRARSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD90</accession>
    <name>A0A2H5VD90_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00708</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000039">
        <property type="protein sequence ID" value="GBC74663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74663">
        <property type="protein sequence ID" value="GBC74663"/>
        <property type="gene ID" value="HRbin05_00708"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="143" mass="16110" checksum="F966890C48E1DC47" modified="2018-02-28" version="1">MKLTATPEQLAEYKEMGKEVIGNPKKLQQIVTNRVKDIITNRYNIKTDKNEAVQTFIKNLSASITQDLVGRDPETVGAIYETIGSDEEFLDLLVDLPDKELIKKADQLLPNVHIQQLWREAKSQTQSGNSNTNTGNRNNTINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD97</accession>
    <name>A0A2H5VD97_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00712</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000040">
        <property type="protein sequence ID" value="GBC74667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74667">
        <property type="protein sequence ID" value="GBC74667"/>
        <property type="gene ID" value="HRbin05_00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036648">
        <property type="entry name" value="CN_Hdrase_a/SCN_Hdrase_g_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56209">
        <property type="entry name" value="SSF56209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="62" mass="7087" checksum="D1D8550045EF3896" modified="2018-02-28" version="1">MGIEEIDAKELEILNSIFLEAAKNPEFRKELLSNPTKALAKYDIPDRLKEMVVNTIQGKEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDA5</accession>
    <name>A0A2H5VDA5_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00714</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000040">
        <property type="protein sequence ID" value="GBC74669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74669">
        <property type="protein sequence ID" value="GBC74669"/>
        <property type="gene ID" value="HRbin05_00714"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="38" mass="4097" checksum="259E06C91AD26C2E" modified="2018-02-28" version="1">MDLNGITPMPMYCITAYASSEDMSSSIRPLSLIISSPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDB4</accession>
    <name>A0A2H5VDB4_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00728</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000043">
        <property type="protein sequence ID" value="GBC74682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74682">
        <property type="protein sequence ID" value="GBC74682"/>
        <property type="gene ID" value="HRbin05_00728"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="171" mass="17739" checksum="80ED9F51529003A2" modified="2018-02-28" version="1">MLPNPLATLLVALSSLPSVNATLVISPGVPVTGSNAISTSGIPNLSRAYVLTRESSPTSLAASSSRHMLCTLTSLSPSLNLTLREPPIAISIVLWNPVVLEPSMTILRITCTSSTTSALSASDIIRAVSNASLLRSCGGSSSISTKHDVPFLARYLITLPFLNSKSAAGSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDN2</accession>
    <name>A0A2H5VDN2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000041">
        <property type="protein sequence ID" value="GBC74671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74671">
        <property type="protein sequence ID" value="GBC74671"/>
        <property type="gene ID" value="HRbin05_00716"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="HTH asnC-type" evidence="1">
        <location>
            <begin position="141"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="294" mass="33373" checksum="595C360DA069804C" modified="2018-02-28" version="1">MDGRDLAILRALLMDGRASYKSIGRIVGLSTSTVRSRVLNMISTGLITRFIASLDLTALGYNLIHVAVKHRGDEDYVMDRLRLLGNILMSVTCVGDITVFGLASKGILKERLDLLPMVLQPHSILYTSSMDAMPRRLLHNDLRIIRQLLMEPRASIKSIASKLNISERTVKRRLDYMLRHNIIHFTVLINPSAMRGFINFSMIITLNDYDSKVMNRVSSMLDSNMLLPLIHVSQNRLVGVLYSESVEGMNELIRRARSIEGVINVDFFIAQRVQWMDGWIGKVIDDMLHVKSYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VDP2</accession>
    <name>A0A2H5VDP2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00727</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000042">
        <property type="protein sequence ID" value="GBC74681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74681">
        <property type="protein sequence ID" value="GBC74681"/>
        <property type="gene ID" value="HRbin05_00727"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="84" mass="9595" checksum="9CFA2555E480C30A" modified="2018-02-28" version="1">MNFMPIMLPPILGRNVNYTRFNMVPLIVLLTAIVLRVAWNILPYMMQVERVVFGISGIVTVAAMLLYINMLHASMDPPYISMPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBC1</accession>
    <name>A0A2H5VBC1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sm domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00014</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000001">
        <property type="protein sequence ID" value="GBC73986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC73986">
        <property type="protein sequence ID" value="GBC73986"/>
        <property type="gene ID" value="HRbin05_00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120114">
        <property type="term" value="C:Sm-like protein family complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016487">
        <property type="entry name" value="Lsm6/sSmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001163">
        <property type="entry name" value="LSM_dom_euk/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11021">
        <property type="entry name" value="PTHR11021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01423">
        <property type="entry name" value="LSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00651">
        <property type="entry name" value="Sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0687">Ribonucleoprotein</keyword>
    <feature type="domain" description="Sm" evidence="2">
        <location>
            <begin position="22"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC73986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="91" mass="10486" checksum="B9866B46108A6486" modified="2018-02-28" version="1">MLIFLVKSLSNQQQQHPKKPLVVLQRAINKKVSVRLKNEAEYRGKMSNVDSYMNLILEDAEEFNGSTHLANYGKVVIRGNNVLFIRLEDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBK3</accession>
    <name>A0A2H5VBK3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-3-methyladenine glycosylase</fullName>
            <ecNumber evidence="2">3.2.2.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">alkA</name>
        <name evidence="2" type="ORF">HRbin05_00105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.21" evidence="2"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74074">
        <property type="protein sequence ID" value="GBC74074"/>
        <property type="gene ID" value="HRbin05_00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052822">
        <property type="term" value="F:DNA-3-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052821">
        <property type="term" value="F:DNA-7-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043916">
        <property type="term" value="F:DNA-7-methylguanine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012904">
        <property type="entry name" value="OGG_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07934">
        <property type="entry name" value="OGG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="1">
        <location>
            <begin position="106"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="279" mass="31997" checksum="C123CCC930131071" modified="2018-02-28" version="1">MKMDAINLKRTLESGQVFLWYERRGIYYIICSSSVVKIESCDGEFVYESRPEHVDVERLFRMDDDIHAINSSIGCKDALIADAIERFKGLRIMRQDPFQCLISFICATNTNIARVRQMLECICRRFGGKIELDGITFHTFPSVRALQDASINDLVGCGLGYRTRFIVQAVRSYAEMDVDDLVKGCYDDARDVLLSIDGVGNKVADCVMLFSLEKLEAFPIDVWIGRVIARYYRHITGIGDMVKFTPPMYRRVSSAMRGYFGMYAGYAQQYLYCYARAYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBM2</accession>
    <name>A0A2H5VBM2_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Purine nucleoside phosphorylase</fullName>
            <shortName evidence="1">PNP</shortName>
            <ecNumber evidence="1">2.4.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mtnP</name>
        <name evidence="3" type="ORF">HRbin05_00121</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">Purine nucleoside phosphorylase involved in purine salvage.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Dimer of a homotrimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74088">
        <property type="protein sequence ID" value="GBC74088"/>
        <property type="gene ID" value="HRbin05_00121"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01963">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="PTHR42679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01694">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="2">
        <location>
            <begin position="14"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="1">
        <location>
            <begin position="62"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="218"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="1">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="1">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="271" mass="30458" checksum="353A2EF859A51440" modified="2018-02-28" version="1">MMSNSSSKDVHAEVAIIGGTGVYDVEMLEDAREVKVYTPYGDASDLITVGKYSDKSVAFLPRHGREHRIPPHRIPARANIWALKHLGVKRIIAPAAVGSLRDDVRPGDIVIADQFIDFTKRREYTFYDGGEVCHVSLADPFCPELRSIVIGECKNLNLKVHEQGTYVCIEGPRYSTRAESRFFRDMMKADIIGMTLVPECILAREMEICYVSIATVTDYDVWAEKPVSTQEVIETLRKNSSNVKRLLKAVIPKIPDERNCICKEALKDAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBN1</accession>
    <name>A0A2H5VBN1_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00129</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000003">
        <property type="protein sequence ID" value="GBC74096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74096">
        <property type="protein sequence ID" value="GBC74096"/>
        <property type="gene ID" value="HRbin05_00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="78" mass="8839" checksum="16B0109A5F845BCB" modified="2018-02-28" version="1">MQDSIQLSEKLYYIGLFIILLVSSILGLYLAQIKSFDSFVAHDLVPINNVKGFPIKQEDYATFVKPDEIPGFIYSLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBQ6</accession>
    <name>A0A2H5VBQ6_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Tryptophan synthase alpha chain</fullName>
            <ecNumber evidence="8">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">trpA</name>
        <name evidence="11" type="ORF">HRbin05_00150</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="2 8">The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the TrpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="8"/>
    <dbReference type="EMBL" id="BEHH01000004">
        <property type="protein sequence ID" value="GBC74117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74117">
        <property type="protein sequence ID" value="GBC74117"/>
        <property type="gene ID" value="HRbin05_00150"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7 8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="288" mass="31732" checksum="A80E2334CA629D39" modified="2018-02-28" version="1">MSSSSSSRSSNNNSSRKENPIDVRLREVMARGEYALIGYMVAGYPDEHTCLDLALAMIDGGVDILEIGIPFSDPIADGPTIQKASYIALSNGITPRKAFDIARRIKDASNTPLVAMTYYNIVYRLGVERFMSMAREHGIDGLIVPDLTYEEADDVIRVAHIHGMDLIFLVAPNTSDERINMIAGVSKGFLYLVSVYGTTGERDRFYEYTTNAIRRVKGLMMGRVPLAVGFGISRKEHVRLMIDAGADAIVVGSAFINIIEKGNNDKDGMLKGIRQLAYELKQATKRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBS6</accession>
    <name>A0A2H5VBS6_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-aminoadipate--LysW ligase LysX</fullName>
            <ecNumber evidence="6">6.3.2.43</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lysX</name>
        <name evidence="6" type="ORF">HRbin05_00170</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimK family. LysX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.43" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000005">
        <property type="protein sequence ID" value="GBC74137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74137">
        <property type="protein sequence ID" value="GBC74137"/>
        <property type="gene ID" value="HRbin05_00170"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009085">
        <property type="term" value="P:lysine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011870">
        <property type="entry name" value="LysX_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004666">
        <property type="entry name" value="RpS6_RimK/Lys_biosynth_LsyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02144">
        <property type="entry name" value="LysX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00768">
        <property type="entry name" value="rimK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="111"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="299" mass="33377" checksum="679A733A87ADAF3B" modified="2018-02-28" version="1">MGSVSKLYILYDLVRWEEKALYEAAVRKGLYVKMLDSKDILIDLNGNSSNNSSSIIHGSSIEVDGHNSILLQRCVSYFRNLHLTAALEGKGYRVINPFQCSVIAGNKLFAHLALVKHGIKAPRSMLAFTQDTVFKAIDALGYPVVLKPTVGSWGRLIALIRDRDAAEAVVEDREHMFPLYQIYYLQEYVRRPPRDIRAIVAGDRVLGAIYRYAGDGQWKTNMALGGKAEPCPISKELEDTCIRACKAVNGEVVGVDLMEDEAKGLLVHEVNPTTEFKNVARVSNSKIADEMIDYIVQRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBW8</accession>
    <name>A0A2H5VBW8_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS</fullName>
            <shortName evidence="1">tRNA(Ile2)-agm2C synthetase</shortName>
            <ecNumber evidence="1">6.3.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA(Ile2) agmatidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">tiaS</name>
        <name evidence="3" type="ORF">HRbin05_00218</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="1">ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>agmatine + ATP + cytidine(34) in tRNA(Ile2) + H2O = 2-agmatinylcytidine(34) in tRNA(Ile2) + AMP + 2 H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:43608"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10626"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83545"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.22"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TiaS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.22" evidence="1"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74184">
        <property type="protein sequence ID" value="GBC74184"/>
        <property type="gene ID" value="HRbin05_00218"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002101">
        <property type="term" value="P:tRNA wobble cytosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01892">
        <property type="entry name" value="tRNA_Ile2_agm2C_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013696">
        <property type="entry name" value="DUF1743"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024913">
        <property type="entry name" value="tRNA_Ile2__agm2C_synt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08489">
        <property type="entry name" value="DUF1743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUF1743" evidence="2">
        <location>
            <begin position="148"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="466" mass="51806" checksum="3A78C8A2E4660A4E" modified="2018-02-28" version="1">MVLLIGIDDTDSRQGRCTTHLAYRIVDFLFSNGYEVEEYPFLARLNPNIPWKTRGNGAVCIKVKVDMESREGEHVMQIVKEMVESNSMLGYGANPGIVFLGRCKNIEPIVRFANDALWRVMSIRGAIKVIEECKNYDCSIEYYAMGNGQGIVGALASIGLASSMLDDYTFEVIAYRRQEMCGLPRLVDEASVMMMDKATHPYTFNNYDYKHARVLITPHGPDPVLFGIRGDDPCILLDALSMLKVHEPLEGYMLFRSNQGTNAHLANMLDASNLKAYTSGYIQGRVASEPLAIEGGHTFFALECYGNNGYGSGDEDGYGKGNVLCAVYEPTGLSPIAQALSIGDVLEVGGGVRKGTSKHPKVLNVEYIKVVDLARKVRYMNPLCICGKRLKSEGKGKGYGCKKCGYRVRDAEKVDVEVARDLRLGLYLPDAKAHRHLTKPLHRYGIKPGCMRLDIDWFNNNSRFTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBX0</accession>
    <name>A0A2H5VBX0_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AsnC_trans_reg domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00219</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74185">
        <property type="protein sequence ID" value="GBC74185"/>
        <property type="gene ID" value="HRbin05_00219"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsnC_trans_reg" evidence="1">
        <location>
            <begin position="6"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="77" mass="8775" checksum="7A119E1E7325017A" modified="2018-02-28" version="1">MPIAFVLINAEMGSEEALIKELKQLDGVKEVYTVYGVYDIIAKVESDSMEKVKETITWKIRRLPNVRSTLTMIVIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBX3</accession>
    <name>A0A2H5VBX3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00222</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74188">
        <property type="protein sequence ID" value="GBC74188"/>
        <property type="gene ID" value="HRbin05_00222"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="295"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="326" mass="36737" checksum="22B784A64752BB93" modified="2018-02-28" version="1">MHIPLKYEPMYISIDPLNKLPLKKIVELKIDKHMLIAMLKHGNTVERINAARALANTTMDSDDVINALREAIVSDAFWGVAAEAAKALASIKGEKAYSALTSIVESIKHPKARRAVVRAIGEFAREDSIQLLNRIVQSDESYYVQAEAVLAIGKSKSKKALPYLMGSLQIRSHNEVVRASAMAAFGEVRDEFSIPVLIDHTRLGEHNRVREAATLALSKYAKGNEKVVDHLIQLLRDHWFRVRINAIKALAEAQEQKALRDLEWVASNDIDARVRRVAEEAIITIREATQVPKELAQMREEVERLKGMSRDMMSRLDMLEREIKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBY1</accession>
    <name>A0A2H5VBY1_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="8">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="8">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">ImGP synthase subunit HisH</fullName>
            <shortName evidence="8">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">hisH</name>
        <name evidence="11" type="ORF">HRbin05_00204</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="8">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="8"/>
    <dbReference type="EC" id="3.5.1.2" evidence="8"/>
    <dbReference type="EMBL" id="BEHH01000006">
        <property type="protein sequence ID" value="GBC74170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74170">
        <property type="protein sequence ID" value="GBC74170"/>
        <property type="gene ID" value="HRbin05_00204"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="6"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="GBC74170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="204" mass="22680" checksum="E5E9BC4587A098B1" modified="2018-02-28" version="1">MSKIAIFDYGAGNIFSIKVALERLCVDVEVIRSMDNLDVYKALILPGVGNFDPAMKSIMPYKDRLLEAIGSGMPMLGICLGMEMLFERSEEGTLPGLSILAGEVVMLPRSVKIPHMGWNRLRINANSSNSVLLNGIDDGTWVYFVHSYHARPKDARVVSARSEYGVEFPAVIEYGNLFGTQFHPEKSGSDGMHMLSNFLNYLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VBZ3</accession>
    <name>A0A2H5VBZ3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00238</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000007">
        <property type="protein sequence ID" value="GBC74204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74204">
        <property type="protein sequence ID" value="GBC74204"/>
        <property type="gene ID" value="HRbin05_00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="64" mass="7106" checksum="900A9DE3BAAABB0E" modified="2018-02-28" version="1">MIMKRERAMHIAIMFFIAGGWGAWVSSVTGSLFILYLTVINIVLGLIFLAYYIRGHATGRGSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC31</accession>
    <name>A0A2H5VC31_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rubrerythrin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HRbin05_00287</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74252">
        <property type="protein sequence ID" value="GBC74252"/>
        <property type="gene ID" value="HRbin05_00287"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01044">
        <property type="entry name" value="Ferritin_CCC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039376">
        <property type="entry name" value="Ferritin_CCC1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003251">
        <property type="entry name" value="Rubrerythrin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02915">
        <property type="entry name" value="Rubrerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Rubrerythrin" evidence="2">
        <location>
            <begin position="16"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="303" mass="33848" checksum="989D2336491FF839" modified="2018-02-28" version="1">MSNDNNNNDRFVEVAGYACRDEYTDYYIYNALASSSVIPKALKGRLALMAEQEYRHYEFWKRYTDRIIVVKEPKIKVLMMKFLALIMGITFVVRMLERHESSVIEGYKGLLHIMKDEDDRRMLEGIIDEEEKHESSLVENISEGRVKYLGFTVLGLSDALIEIAGIHAGTLGVYTDTFKAGLAGLIAGVAASIAMASAAYNQAKQTEGVKASSAATYTGIAYVVTALLLALPYFIVHDILEALLISLMISIAILAYIALYSHVLFNRNFFRELGETTGIIFGATIALYAFGELIRIYFNLQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC47</accession>
    <name>A0A2H5VC47_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000010">
        <property type="protein sequence ID" value="GBC74265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74265">
        <property type="protein sequence ID" value="GBC74265"/>
        <property type="gene ID" value="HRbin05_00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="120" mass="13460" checksum="CA8E2810C09ED8DC" modified="2018-02-28" version="1">MALIYVVPTAVVGAVMLAIFLTSIPMASKDYALEVDAFKDNDDMMLMYRVVIVNTGRNDVTNVVVDYGTYKDFIPRIKPGEKIILSPRDDASKEKVTVTAEPSIYIVKEYRNLAKMVKVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VC67</accession>
    <name>A0A2H5VC67_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsH</name>
        <name evidence="4" type="synonym">rps8</name>
        <name evidence="5" type="ORF">HRbin05_00327</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000011">
        <property type="protein sequence ID" value="GBC74289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74289">
        <property type="protein sequence ID" value="GBC74289"/>
        <property type="gene ID" value="HRbin05_00327"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_A">
        <property type="entry name" value="Ribosomal_S8_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="GBC74289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="130" mass="14646" checksum="57BED7A4A65A60A8" modified="2018-02-28" version="1">MPALNVVANLFSTIYNNEMRRKRSCIVMPTSKLALEVLRVMKEHGFIGDYQYVDDGRGGKAVVQLLSRVNKCNVITPRFSVKKDGYDEWDRQYLPSYSRGILIVSTPLGVMSHREAQSKGIGGVLIGYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCF0</accession>
    <name>A0A2H5VCF0_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inosine-5'-monophosphate dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.205</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">guaB</name>
        <name evidence="3" type="ORF">HRbin05_00286</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000009">
        <property type="protein sequence ID" value="GBC74251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74251">
        <property type="protein sequence ID" value="GBC74251"/>
        <property type="gene ID" value="HRbin05_00286"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="82"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="146"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="403" mass="45110" checksum="F02852BB00E76519" modified="2018-02-28" version="1">MVIRVLEPELYAQFSALRDRSVGDIMQEPVVASQDSTISQIIGLMDKHDAYTVFIDFNGRIASINMRDILEYRDIDHAKPSMVGKIVPPLARTQRIGYAARIMGEYRLRALPVVEDGRIVGQITSDAILRMVNAYGIDNVSAGDIMTPNPIIVDADSKIASARGIMIRHKIDHLPVVNDGKVAGILTSRHLLIALKPPESSKGKADIISNKTRMMDLKVSGLFDKHIVASEPNESVKSIVSKMIDNRVAYTFVTVGEELQGIITHRDVVGLLQEMVREEIPLYIVGLPEDPFDAELAKSKFATLVRLMRKVVHDLSEARCNIKIKDMGGERRRYEVKVNIVTLSDTMSYTANGYDLAMIFDQISDSFKKRIAHRENRGKGDAKGRGRKGRESIRYKVDFYTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCG2</accession>
    <name>A0A2H5VCG2_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid protease GluP</fullName>
            <ecNumber evidence="7">3.4.21.105</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gluP</name>
        <name evidence="7" type="ORF">HRbin05_00418</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.105" evidence="7"/>
    <dbReference type="EMBL" id="BEHH01000015">
        <property type="protein sequence ID" value="GBC74378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74378">
        <property type="protein sequence ID" value="GBC74378"/>
        <property type="gene ID" value="HRbin05_00418"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="44"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="GBC74378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="183" mass="20041" checksum="51E63A5BB98642CC" modified="2018-02-28" version="1">MLPPVTLALLAVNVTVFILLQNTNWYRFGSIPSYLLNDPSMFLITAFTSMFLHANIVHIAFNMLALVALGRVIEDAIGSMRYIIVYILSGLSGVALHTIYSLTTNNGFNTPMVGASGAISGIIGLAAAMGDKFAYIWLAVQFIFAIAGLSSIAYFAHIGGFIFGFMMGRLYHDRMYRDSTYLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCN8</accession>
    <name>A0A2H5VCN8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HRbin05_00503</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000020">
        <property type="protein sequence ID" value="GBC74462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74462">
        <property type="protein sequence ID" value="GBC74462"/>
        <property type="gene ID" value="HRbin05_00503"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023391">
        <property type="entry name" value="Prot_translocase_SecE_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008158">
        <property type="entry name" value="Translocase_Sec61-g"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103456">
        <property type="entry name" value="SSF103456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00327">
        <property type="entry name" value="secE_euk_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="GBC74462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="61" mass="7035" checksum="238B4436562F1F73" modified="2018-02-28" version="1">MLARIENRLREMYNTLKLTKKPDREEYNIHLRMLLLGLGVVGVLAFIIQLIATYITLTFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCS7</accession>
    <name>A0A2H5VCS7_9ARCH</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Shikimate dehydrogenase (NADP(+))</fullName>
            <shortName evidence="4">SDH</shortName>
            <ecNumber evidence="1 4">1.1.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 8" type="primary">aroE</name>
        <name evidence="8" type="ORF">HRbin05_00543</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.25" evidence="1 4"/>
    <dbReference type="EMBL" id="BEHH01000023">
        <property type="protein sequence ID" value="GBC74502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74502">
        <property type="protein sequence ID" value="GBC74502"/>
        <property type="gene ID" value="HRbin05_00543"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011342">
        <property type="entry name" value="Shikimate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00507">
        <property type="entry name" value="aroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="6">
        <location>
            <begin position="44"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_C" evidence="7">
        <location>
            <begin position="283"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate binding" evidence="4">
        <location>
            <begin position="52"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="162"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="GBC74502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="319" mass="35322" checksum="7F6B36766586B261" modified="2018-02-28" version="1">MINKGRYGNGGSSSAMMDSKNGRSSNDSNSSISISNNDGKIFCVIGDPVEHSLSPAMHNAVFSSLGLGYRYIAMRVKEHELSSAVEMLKDRALGFNVTIPHKIRIMDMLDDLDPLCKRVNAVNTVKVDGSRLKGYNTDVYGFIQPLRRRGIELRGKSVMIMGAGGAARAVLIALIDEHVGEVIIASRRVDDAKVKALYEMAVSNGIECRIVQLEYARMYSKQCYLIVNATPIGMQGYHGYEDVSILDSNDIDSRSIVYDLVYRPMETRLIRNALNADAMIIHGYEMLVEQGAKALDIWLGIDAPRDVMSNAVLRYLACW</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCU8</accession>
    <name>A0A2H5VCU8_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HRbin05_00561</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="BEHH01000025">
        <property type="protein sequence ID" value="GBC74519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74519">
        <property type="protein sequence ID" value="GBC74519"/>
        <property type="gene ID" value="HRbin05_00561"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="GBC74519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="378" mass="44260" checksum="D899D9D9B0B74FB5" modified="2018-02-28" version="1">MSSKDESIFSKEALMHTDAGKDILKQAMLRSERYKQFQYYKELADREFPRFLDRFVRELHSSIINDDDPLSTLGNFIREAEPDGFILERIFSMDAIKVEEVRSRLADVDRCRDRVLRLLDSNYVKMTYPVFYALYDGACSYLNINASDAERDVLIDGHVIAIDLSEPMDRIMDMDEDVEYLDDYKLICPYMLKIARRKISSIGKDILEAFEQGFRDAKHGQYKDLILKNNPTAMDEESMNECYKKYRAVMGTAGRNMVLKDSPLRRIFYHGMARAGESVGCANEIEDSIKGRVIKVPSWPLYYALNTGDIRLAFDLTFRKSKIYLDDALIAIDMLPERFSTKHFLEFMVLSVRHYNEYWYRRVKEYDLNIFTAGLKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VCX3</accession>
    <name>A0A2H5VCX3_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Metalloprotease TldD</fullName>
            <ecNumber evidence="6">3.4.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tldD</name>
        <name evidence="6" type="ORF">HRbin05_00584</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase U62 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="6"/>
    <dbReference type="EMBL" id="BEHH01000027">
        <property type="protein sequence ID" value="GBC74542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74542">
        <property type="protein sequence ID" value="GBC74542"/>
        <property type="gene ID" value="HRbin05_00584"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045569">
        <property type="entry name" value="Metalloprtase-TldD/E_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045570">
        <property type="entry name" value="Metalloprtase-TldD/E_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002510">
        <property type="entry name" value="Metalloprtase-TldD/E_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025502">
        <property type="entry name" value="TldD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035068">
        <property type="entry name" value="TldD/PmbA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036059">
        <property type="entry name" value="TldD/PmbA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01523">
        <property type="entry name" value="PmbA_TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19289">
        <property type="entry name" value="PmbA_TldD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19290">
        <property type="entry name" value="PmbA_TldD_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004919">
        <property type="entry name" value="TldD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111283">
        <property type="entry name" value="SSF111283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PmbA_TldD" evidence="3">
        <location>
            <begin position="37"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_M" evidence="5">
        <location>
            <begin position="132"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="PmbA_TldD_C" evidence="4">
        <location>
            <begin position="251"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF19290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="GBC74542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="487" mass="53228" checksum="F11BD3E9F85B3312" modified="2018-02-28" version="1">MIEYTIIRSIVLAVYMHLADPDILNLVLNTSTAQYTEVRYHARTLNEIRIVDGRVERARSVTKSGVGIRVLKYGRWGFSSTSIITRDELIRALEQAIKSASAKSYGSDTNTVKGLAEARLARGLFMPEINGKLEDHSIEEKVRIAREAEKEARKGSKSKDVRSALCTYKEMIDAKVIVSSDGASVELYDSKPEFVVNAIAGKGSIKVSASEGVCVTGGWNDLFKDKDHLAIAREAAEKATRLLNAKQPRGERTTIILDPAMVGLLAHEAIGHVVEADFVLSGSIARDLLGKKVASELVTLVDSGASNIVPNAAGTVFVDDEGVMTRSVRIIDKGIMSSYLHNRESAYIFGVEPTGNARAFEYNDEPLIRMRNTYIEPGDYMLDEMIKEVKHGYMLKGARNGQADANGEFMFGAEEAYLIEHGEVKELFRGVSISGITIDVLKSIDAISSSKDFKYDIGTGYCGKYQPMKVDGGGSYVRCNAIVGGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2018-02-28" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A2H5VD11</accession>
    <name>A0A2H5VD11_9ARCH</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Succinate semialdehyde dehydrogenase [NAD(P)+] Sad</fullName>
            <ecNumber evidence="3">1.2.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sad</name>
        <name evidence="3" type="ORF">HRbin05_00625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">archaeon HR05</name>
        <dbReference type="NCBI Taxonomy" id="2035441"/>
        <lineage>
            <taxon>Archaea</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="submission" date="2017-09" db="EMBL/GenBank/DDBJ databases">
            <title>Metaegenomics of thermophilic ammonia-oxidizing enrichment culture.</title>
            <authorList>
                <person name="Kato S."/>
                <person name="Suzuki K."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.16" evidence="3"/>
    <dbReference type="EMBL" id="BEHH01000031">
        <property type="protein sequence ID" value="GBC74582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="GBC74582">
        <property type="protein sequence ID" value="GBC74582"/>
        <property type="gene ID" value="HRbin05_00625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000236308">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009013">
        <property type="term" value="F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07100">
        <property type="entry name" value="ALDH_SSADH1_GabD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044148">
        <property type="entry name" value="ALDH_GabD1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="4"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="GBC74582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000236308"/>
        </source>
    </evidence>
    <sequence length="465" mass="51570" checksum="F49D619240763A8D" modified="2018-02-28" version="1">MGSNRILTINPASEEVIGEHDTMSMDEVIARVKKAKEAFQLWRRDAHRRASVLYEIASILRKEKEHLARVATMEMGKTIREARAEVEKCAWTIEYFADNGEHFIDDEVTVTDARKTFIAFEPLGVIGSIMPWNFPYWQSIRFAAPALMAGNTIAMKPSSITPQCGKELERIFSCVDNLGIFSIVIGDGRVGEMLIDSPVDAVTFTGSVEVGAKVASRAAMHVKKCVLELGGSDPFIVLDDADVEKASSAAVKGRFINNGQSCIASKRFIVMRSVAKEFIEAFARKAERMKVGDPMHEDTELGPLVNKHALEYIDGIVKETVKEGGGEVLIGGERVGSKGYYYAPTILTNVKERMRIVREEVFGPVAPIMVVDDEKEAIRLANDSEFGLGASVWTTDLDRAERVARAIEAGLVTVNNVVVSDPRVPFGGVKKSGFGRELSRYGMLEFMNIKTVRFYDQLIHYHHVE</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>