#ncbi_taxid	cluster_id	cluster_size	best_described_by
224325	CL:0	2395	mixed, incl. metabolic process, and Membrane
224325	CL:10	2370	mixed, incl. metabolic process, and Membrane
224325	CL:101	71	ribosome
224325	CL:1011	5	Tryptophan biosynthesis
224325	CL:1022	6	chorismate biosynthetic process, and 3-dehydroquinate synthase
224325	CL:103	63	ribosome
224325	CL:1033	6	Novobiocin biosynthesis, and Peroxidase
224325	CL:1044	21	Lysine biosynthesis, and Arginine biosynthesis
224325	CL:1045	11	Arginine biosynthesis, and ATP-grasp fold, RimK-type
224325	CL:1047	6	Arginine biosynthesis
224325	CL:105	57	ribosome
224325	CL:106	43	Ribosome
224325	CL:1067	7	Lysine biosynthesis, and Aspartate kinase
224325	CL:108	21	Ribosome
224325	CL:1085	40	nucleoside monophosphate metabolic process, and One carbon pool by folate
224325	CL:1086	28	ribonucleoside monophosphate biosynthetic process, and One carbon pool by folate
224325	CL:1087	18	Purine biosynthesis, and One carbon pool by folate
224325	CL:1089	12	'de novo' IMP biosynthetic process, and One carbon pool by folate
224325	CL:109	16	Ribosome
224325	CL:1091	6	phosphoribosylformylglycinamidine synthase activity, and 'de novo' AMP biosynthetic process
224325	CL:111	9	Ribosome
224325	CL:1122	10	'de novo' UMP biosynthetic process
224325	CL:1123	5	Pyrimidine biosynthesis
224325	CL:1132	5	'de novo' UMP biosynthetic process
224325	CL:1141	12	nucleobase-containing compound kinase activity, and Pyrimidine metabolism
224325	CL:1143	6	mixed, incl. pyrimidine deoxyribonucleotide biosynthetic process, and Cobalamin
224325	CL:1164	29	mixed, incl. Ammonia transport, and Nitrogen regulatory protein PII
224325	CL:1166	16	mixed, incl. Selenocompound metabolism, and Adenosylhomocysteinase-like
224325	CL:1169	5	mixed, incl. Rhodanese-like domain, and Thioredoxin reductase
224325	CL:1184	7	mixed, incl. sulfate assimilation, and Adenosylhomocysteinase-like
224325	CL:1202	10	Ammonia transport, and Nitrogen regulatory protein PII
224325	CL:1204	5	Ammonium transporter, conserved site, and Nitrogen regulatory protein PII
224325	CL:1222	84	Carbon metabolism, and Valine, leucine and isoleucine biosynthesis
224325	CL:1223	56	Citrate cycle (TCA cycle), and Branched-chain amino acid biosynthesis
224325	CL:1224	47	Citrate cycle (TCA cycle), and Branched-chain amino acid biosynthesis
224325	CL:1225	37	Citrate cycle (TCA cycle), and Pyruvate metabolism
224325	CL:1226	29	Pyruvate metabolism, and Citrate synthase
224325	CL:1227	21	Citrate cycle (TCA cycle), and leucine biosynthetic process
224325	CL:1228	14	Nitrotoluene degradation, and leucine biosynthetic process
224325	CL:1231	8	Nitrotoluene degradation
224325	CL:1255	7	mixed, incl. 2-oxoglutarate synthase activity, and glyoxylate cycle
224325	CL:1269	5	mixed, incl. Citrate synthase, and Malate dehydrogenase, type 3
224325	CL:1283	8	CoA-ligase, and Succinate dehydrogenase, cytochrome b556 subunit
224325	CL:1299	6	leucine biosynthetic process
224325	CL:13	2365	mixed, incl. metabolic process, and Membrane
224325	CL:1318	5	mixed, incl. Biotin metabolism, and Biotin-binding site
224325	CL:1334	28	mixed, incl. Pentose phosphate pathway, and Glycolysis
224325	CL:1335	23	Pentose phosphate pathway, and Glycolysis
224325	CL:1336	17	Glycolysis, and Pentose phosphate pathway
224325	CL:1339	6	Glycolysis
224325	CL:1357	5	Carbohydrate kinase PfkB, and diphosphotransferase activity
224325	CL:1369	6	Succinyl-CoA synthetase-like, flavodoxin domain, and Orotidine 5'-phosphate decarboxylase domain
224325	CL:1380	5	mixed, incl. GroES-like superfamily, and Mandelate racemase-like
224325	CL:1394	19	mixed, incl. Nicotinate and nicotinamide metabolism, and Riboflavin biosynthesis
224325	CL:1395	11	Riboflavin biosynthesis, and Thiamine biosynthesis
224325	CL:1397	5	Thiamine biosynthesis
224325	CL:140	5	Ribosomal protein L37ae/L37e, and Ribosomal protein L2
224325	CL:1407	5	Riboflavin biosynthesis
224325	CL:1417	6	NAD biosynthetic process, and Nicotinate phosphoribosyltransferase family
224325	CL:1431	14	mostly uncharacterized, incl. SpoVG, and Hypusine
224325	CL:1432	8	mixed, incl. Hypusine, and Ureohydrolase
224325	CL:1448	5	mixed, incl. AF1782-like superfamily, and NfeD-like, C-terminal domain
224325	CL:1459	7	mixed, incl. RNA ligase, and Na+/H+ exchanger
224325	CL:1480	39	mixed, incl. lipid biosynthetic process, and Terpenoid backbone biosynthesis
224325	CL:1481	28	mixed, incl. lipid biosynthetic process, and Ubiquinone and other terpenoid-quinone biosynthesis
224325	CL:1482	18	mixed, incl. lipid biosynthetic process, and Integral membrane protein DUF92
224325	CL:1485	11	lipid biosynthetic process, and Polyprenyl synthetase, conserved site
224325	CL:1487	5	Phospholipid metabolism
224325	CL:1497	5	Isoprene biosynthesis, and Polyprenyl synthetase, conserved site
224325	CL:1517	10	mixed, incl. Ubiquinone and other terpenoid-quinone biosynthesis, and Cell shape
224325	CL:1520	5	mixed, incl. Lysine-tRNA ligase, and Uncharacterised protein family AF1218
224325	CL:153	16	ribosomal subunit, and Ribosome
224325	CL:1537	7	mixed, incl. SMCs flexible hinge, and Segregation and condensation protein A
224325	CL:155	10	mixed, incl. small ribosomal subunit, and Ribosomal protein S8
224325	CL:1558	31	mostly uncharacterized, incl. DNA repair, and Helicase HerA
224325	CL:1559	19	mixed, incl. Helicase HerA, and DNA repair
224325	CL:1560	11	mostly uncharacterized, incl. Reverse gyrase, and UPF0759 superfamily
224325	CL:1563	5	mixed, incl. Reverse gyrase, and Nucleoside-triphosphatase, THEP1 type
224325	CL:1583	5	mixed, incl. SbcC-like, and NurA domain
224325	CL:1596	12	mixed, incl. Nitroreductase-like, and Inositol phosphate metabolism
224325	CL:1598	5	mixed, incl. Endonuclease V, and Endonuclease III
224325	CL:1610	5	Inositol phosphate metabolism, and Helicase SMUBP-2/Hcs1-like
224325	CL:1626	15	mixed, incl. Menaquinone biosynthesis, and F420, menaquinone cofactor biosynthesis
224325	CL:1627	8	Menaquinone biosynthesis, and Glycosyltransferase AglJ
224325	CL:1643	5	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity, and F420-0:Gamma-glutamyl ligase
224325	CL:1655	12	mixed, incl. AMP phosphorylase, and Thi4 family
224325	CL:1657	5	mixed, incl. Thi4 family, and DHHA1 domain
224325	CL:1669	5	AMP phosphorylase, and Metallophosphoesterase, calcineurin superfamily
224325	CL:1678	43	Porphyrin and chlorophyll metabolism, and transition metal ion transport
224325	CL:1679	36	Porphyrin and chlorophyll metabolism, and transition metal ion transport
224325	CL:1680	28	Porphyrin and chlorophyll metabolism, and cobalt ion transport
224325	CL:1681	20	cobalamin biosynthetic process, and Tetrapyrrole methylase
224325	CL:1682	13	cobalamin biosynthetic process, and Tetrapyrrole methylase
224325	CL:1684	8	Tetrapyrrole methylase, and CbiD
224325	CL:17	2360	mixed, incl. metabolic process, and Membrane
224325	CL:1707	7	cobalt ion transport, and Cobalt transport protein
224325	CL:1721	6	Porphyrin biosynthesis
224325	CL:1735	8	mixed, incl. Cobalamin-5-phosphate synthase, and Methyltransferase, class D
224325	CL:175	5	mixed, incl. Repressor, and Ribosomal protein S17
224325	CL:1750	7	mixed, incl. Tyrosine metabolism, and Putative antitoxin
224325	CL:1765	6	mixed, incl. Exosortase, and Phosphatidylserine decarboxylase
224325	CL:1782	26	mostly uncharacterized, incl. Riboflavin metabolism, and Periplasmic copper-binding protein (NosD)
224325	CL:1784	10	mixed, incl. Riboflavin metabolism, and Periplasmic copper-binding protein (NosD)
224325	CL:1785	5	FMN metabolic process, and Band 7 domain
224325	CL:1794	5	Periplasmic copper-binding protein (NosD), and Pterin binding enzyme
224325	CL:1810	12	mostly uncharacterized, incl. DNA methylase, and PQQ-like domain
224325	CL:1812	5	mixed, incl. Uncharacterised domain MJ0874, and Adenosylcobinamide amidohydrolase
224325	CL:1824	5	mixed, incl. DNA methylase, and Helicase/UvrB, N-terminal
224325	CL:1834	6	mixed, incl. DEAD/H associated, and Phosphoesterase, MJ0037
224325	CL:1852	166	mixed, incl. Transferase, and Transmembrane helix
224325	CL:1853	88	mixed, incl. His Kinase A (phosphoacceptor) domain, and Bacterial chemotaxis
224325	CL:1854	70	mixed, incl. Phosphoprotein, and PAS domain
224325	CL:1855	62	mixed, incl. Bacterial chemotaxis, and His Kinase A (phosphoacceptor) domain
224325	CL:1856	53	mixed, incl. Bacterial chemotaxis, and His Kinase A (phosphoacceptor) domain
224325	CL:1857	29	mixed, incl. His Kinase A (phosphoacceptor) domain, and cheY-homologous receiver domain
224325	CL:1859	15	Histidine kinase domain, and cheY-homologous receiver domain
224325	CL:1861	7	PAS fold-3, and cheY-homologous receiver domain
224325	CL:1879	5	mixed, incl. Haloacid dehalogenase-like hydrolase, and Predicted membrane protein (DUF2070)
224325	CL:1897	7	mixed, incl. PAS fold, and GvpD gas vesicle protein
224325	CL:191	14	structural constituent of ribosome
224325	CL:1915	20	Bacterial chemotaxis, and Flagellin, archaea
224325	CL:1916	10	mixed, incl. Flagellin, archaea, and PAXNEB protein
224325	CL:1918	5	cell projection, and PAXNEB protein
224325	CL:1935	10	Bacterial chemotaxis
224325	CL:1939	5	Bacterial chemotaxis
224325	CL:1962	6	mixed, incl. ATPase, AAA-3, and Ta1353-like superfamily
224325	CL:1978	8	mixed, incl. TspO/MBR family, and CASTOR,  ACT domain
224325	CL:1993	18	mixed, incl. FtsX-like permease family, and ABC transporter, conserved site
224325	CL:1994	12	mixed, incl. MacB-like periplasmic core domain, and MatE
224325	CL:1995	6	mixed, incl. Molybdenum-binding protein ModE, N-terminal, and Uncharacterised conserved protein UCP004897, ACT- type
224325	CL:2006	6	mixed, incl. MatE, and TRAPP II complex, Trs120
224325	CL:2017	6	mixed, incl. DNA-binding HTH domain, TetR-type, and Protein of unknown function DUF1284
224325	CL:2028	78	mixed, incl. Nucleotide-diphospho-sugar transferases, and Glycosyl transferases group 1
224325	CL:2029	49	mixed, incl. Glycosyl transferases group 1, and Nucleotide-diphospho-sugar transferases
224325	CL:2031	38	mixed, incl. Nucleotide-diphospho-sugar transferases, and Glycosyl transferases group 1
224325	CL:2033	29	mixed, incl. Amino sugar and nucleotide sugar metabolism, and Nucleotide-diphospho-sugar transferases
224325	CL:2034	22	Amino sugar and nucleotide sugar metabolism, and Nucleotide-diphospho-sugar transferases
224325	CL:2035	12	mixed, incl. Oligosaccharyl transferase STT3 subunit, and Amino sugar and nucleotide sugar metabolism
224325	CL:2037	6	mixed, incl. UDP-glucose/GDP-mannose dehydrogenase, and NAD(P)H-binding 
224325	CL:2058	10	Streptomycin biosynthesis, and RmlC-like cupin domain superfamily
224325	CL:2060	5	Acarbose and validamycin biosynthesis, and Glycosyltransferase like family 2
224325	CL:2078	5	ABC-2 type transporter, and AAA domain
224325	CL:2095	6	mixed, incl. Methyltransferase FkbM, and Glycosyl transferase, family 1
224325	CL:21	2355	mixed, incl. metabolic process, and Membrane
224325	CL:2112	6	mixed, incl. GtrA-like protein, and Glycosyltransferase family 87
224325	CL:2126	29	mostly uncharacterized, incl. Amine oxidase, and Peptidase M28
224325	CL:2127	15	mostly uncharacterized, incl. Amine oxidase, and Peptidase M28
224325	CL:2131	7	mixed, incl. AP endonuclease 1, and Protein of unknown function DUF2298
224325	CL:2157	11	mostly uncharacterized, incl. NUDIX hydrolase, and MMPL family
224325	CL:2159	5	EamA domain, and Signal
224325	CL:2183	54	mostly uncharacterized, incl. Radical SAM, and ASCH domain
224325	CL:2184	44	mostly uncharacterized, incl. Radical SAM, and ASCH domain
224325	CL:2185	33	mostly uncharacterized, incl. ASCH domain, and Acyl-CoA N-acyltransferase
224325	CL:2186	27	mostly uncharacterized, incl. ASCH domain, and Radical SAM
224325	CL:2187	19	mixed, incl. ASCH domain, and Radical SAM
224325	CL:2189	7	mixed, incl. Protein of unknown function DUF401, and ASCH domain
224325	CL:2208	5	mixed, incl. Fumarylacetoacetase-like, C-terminal, and ASCH domain
224325	CL:2224	8	mixed, incl. Stage II sporulation protein M, and Protein of unknown function DUF63
224325	CL:2239	6	mixed, incl. Protein of unknown function DUF554, and PAC2 family
224325	CL:2251	7	mixed, incl. Organic radical, and Organic radical enzyme activase
224325	CL:2272	6	mixed, incl. Putative pyruvate format-lyase activating enzyme (DUF1786), and Phosphotransferase KptA/Tpt1
224325	CL:2291	6	mixed, incl. Metalloprotease TldD/PmbA, and FAD dependent protein
224325	CL:23	2342	mixed, incl. metabolic process, and Membrane
224325	CL:2310	10	mixed, incl. Metalloprotease, and YbhB/YbcL
224325	CL:2311	5	Metalloprotease, and TraB family
224325	CL:2320	5	mixed, incl. YbhB/YbcL, and LysE type translocator
224325	CL:233	5	mixed, incl. exopeptidase activity, and Domain found in IF2B/IF5
224325	CL:2332	6	mixed, incl. MarC family integral membrane protein, and Transcription regulator, CBS domain-containing, predicted
224325	CL:2344	5	mixed, incl. DJ-1/PfpI, and Conserved hypothetical protein CHP00300
224325	CL:2356	158	mixed, incl. Methane metabolism, and Coiled coil
224325	CL:2357	133	mixed, incl. Methane metabolism, and Coiled coil
224325	CL:2358	104	mixed, incl. Methane metabolism, and iron-sulfur cluster assembly
224325	CL:2359	73	mixed, incl. Methane metabolism, and AAA domain
224325	CL:2360	66	mixed, incl. Methane metabolism, and Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type
224325	CL:2361	56	mixed, incl. Methane metabolism, and Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type
224325	CL:2362	48	mixed, incl. Methane metabolism, and Uncharacterised ArCR, COG2043
224325	CL:2363	41	Methane metabolism, and Flavoprotein-like superfamily
224325	CL:2365	30	Methane metabolism
224325	CL:2366	22	Methane metabolism
224325	CL:2367	13	mixed, incl. lactate oxidation, and Formylmethanofuran dehydrogenase, subunit B
224325	CL:2369	7	mixed, incl. Formylmethanofuran dehydrogenase, subunit B, and Amidohydrolase 3
224325	CL:2383	5	lactate oxidation
224325	CL:2393	5	Prismane/CO dehydrogenase family, and acetate metabolic process
224325	CL:2410	5	mixed, incl. 4-HFC-P synthase, and Tyramine--L-glutamate ligase
224325	CL:2433	5	mixed, incl. Archaeoflavoprotein AfpA, and Sugar fermentation stimulation protein
224325	CL:2444	7	mixed, incl. Sugar phosphate transporter, and Ribonuclease M5-like, TOPRIM domain
224325	CL:2458	6	mixed, incl. Endonuclease VapC20, and Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type
224325	CL:2472	10	mixed, incl. NifU-like domain, and AF1104-like superfamily
224325	CL:2474	5	mixed, incl. NifU-like domain, and D-Arginine and D-ornithine metabolism
224325	CL:248	18	tRNA aminoacylation for protein translation, and rRNA methylation
224325	CL:2491	7	mixed, incl. PINc domain ribonuclease, and TRAM domain
224325	CL:250	12	Aminoacyl-tRNA synthetase, class Ia, anticodon-binding, and Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)
224325	CL:2504	31	mixed, incl. iron-sulfur cluster assembly, and DsrE/DsrF/DrsH-like family
224325	CL:2506	18	mixed, incl. iron-sulfur cluster assembly, and DsrE/DsrF/DrsH-like family
224325	CL:2507	10	mixed, incl. DsrE/DsrF/DrsH-like family, and HAD superfamily
224325	CL:2509	5	mixed, incl. Cysteine desulfurase, and NifU-like N terminal domain
224325	CL:252	5	mixed, incl. rRNA methylation, and Valine-tRNA ligase
224325	CL:2527	5	2Fe-2S, and Sulphur relay, DsrE/F-like protein
224325	CL:2549	5	mixed, incl. Mrp, conserved site, and Domain of unknown function DUF1724
224325	CL:2565	29	mixed, incl. Thioredoxin-like superfamily, and Winged helix-turn helix
224325	CL:2566	20	mixed, incl. Winged helix-turn helix, and DDE superfamily endonuclease
224325	CL:2567	10	mixed, incl. Winged helix-turn helix, and DDE superfamily endonuclease
224325	CL:2569	5	mixed, incl. Thioredoxin, and WD40/YVTN repeat-like-containing domain superfamily
224325	CL:2588	6	mixed, incl. Redox-active center, and Tc1-like transposase, DDE domain
224325	CL:2606	5	mixed, incl. SWI2/SNF2 ATPase, and Protein of unknown function DUF45
224325	CL:2622	25	mostly uncharacterized, incl. FldB/FldC dehydratase alpha/beta subunit, and Rubredoxin-like domain
224325	CL:2623	19	mostly uncharacterized, incl. FldB/FldC dehydratase alpha/beta subunit, and SHOCT domain
224325	CL:2624	14	mixed, incl. FldB/FldC dehydratase alpha/beta subunit, and SHOCT domain
224325	CL:2625	7	mixed, incl. Putative NAD(P)H nitroreductase YdjA-like, and Phage integrase family
224325	CL:2638	7	mixed, incl. FldB/FldC dehydratase alpha/beta subunit, and SHOCT domain
224325	CL:2651	5	mixed, incl. Protein of unknown function DUF1805, and Rubredoxin
224325	CL:2660	6	mixed, incl. Cyclic nucleotide-binding domain, and Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily
224325	CL:2671	170	mostly uncharacterized, incl. Thiolase-like, and AMP-binding enzyme
224325	CL:2673	154	mostly uncharacterized, incl. Thiolase-like, and Rubredoxin-like zinc ribbon domain (DUF35_N)
224325	CL:2674	143	mostly uncharacterized, incl. Thiolase-like, and Rubredoxin-like zinc ribbon domain (DUF35_N)
224325	CL:2675	127	mostly uncharacterized, incl. Thiolase-like, and Rubredoxin-like zinc ribbon domain (DUF35_N)
224325	CL:2676	110	mixed, incl. Thiolase-like, and Acyl-CoA dehydrogenase, middle domain
224325	CL:2677	97	mixed, incl. Thiolase-like, and Acyl-CoA dehydrogenase, middle domain
224325	CL:2679	80	mixed, incl. Thiolase-like, and Enoyl-CoA hydratase/isomerase
224325	CL:2680	71	mixed, incl. Thiolase-like, and Enoyl-CoA hydratase/isomerase
224325	CL:2681	57	mixed, incl. Thiolase-like, and Enoyl-CoA hydratase/isomerase
224325	CL:2682	45	mixed, incl. Thiolase-like, and Enoyl-CoA hydratase/isomerase
224325	CL:2683	38	mixed, incl. Enoyl-CoA hydratase/isomerase, and Thiolase-like
224325	CL:2685	22	mixed, incl. Enoyl-CoA hydratase/isomerase, and Benzoate degradation
224325	CL:2687	17	Enoyl-CoA hydratase/isomerase, and Benzoate degradation
224325	CL:2688	11	Enoyl-CoA hydratase/isomerase, and 3-hydroxyacyl-CoA dehydrogenase
224325	CL:2689	6	Enoyl-CoA hydratase/isomerase, and 3-hydroxyacyl-CoA dehydrogenase
224325	CL:2700	5	Enoyl-CoA hydratase/isomerase, and 3-hydroxyacyl-CoA dehydrogenase
224325	CL:2709	6	mixed, incl. Electron transfer flavoprotein domain, and 3-hydroxyacyl-CoA dehydrogenase, conserved site
224325	CL:2733	13	mixed, incl. CoA-transferase family III, and DUF35 OB-fold domain, acyl-CoA-associated
224325	CL:2734	7	mixed, incl. CoA-transferase family III, and Exonuclease
224325	CL:2747	6	mixed, incl. DUF35 OB-fold domain, acyl-CoA-associated, and Acetyl-coenzyme A synthetase N-terminus
224325	CL:2759	5	Rubredoxin-like zinc ribbon domain (DUF35_N), and Thiolase
224325	CL:2771	12	mixed, incl. AMP-binding, conserved site, and Protein of unknown function DUF116
224325	CL:2775	6	mixed, incl. N-terminal half of MaoC dehydratase, and Thiolase
224325	CL:2795	10	mixed, incl. O-methyltransferase, and Periplasmic binding protein
224325	CL:2796	5	mixed, incl. Beta-ketoacyl synthase, N-terminal domain, and 3-hydroxyacyl-CoA dehydrogenase
224325	CL:28	2337	mixed, incl. metabolic process, and Membrane
224325	CL:2805	5	mixed, incl. O-methyltransferase, and Periplasmic binding protein
224325	CL:2823	6	mixed, incl. Sodium/calcium exchanger protein, and Protein of unknown function DUF1646
224325	CL:284	19	RNA polymerase, and Basal transcription factors
224325	CL:2843	14	mixed, incl. Alpha/Beta hydrolase fold, and AMP-binding enzyme
224325	CL:2845	5	mixed, incl. MerR, DNA binding, and Uncharacterised conserved protein UCP037373, transcriptional regulator, AF0674
224325	CL:286	10	RNA polymerase
224325	CL:2861	5	mixed, incl. Dioxygenase, and MMPL family
224325	CL:2870	13	mostly uncharacterized, incl. KR domain, and DRTGG domain
224325	CL:2872	6	mixed, incl. KR domain, and Cupin 2, conserved barrel
224325	CL:2896	16	mixed, incl. B12 binding domain, and Uroporphyrinogen decarboxylase (URO-D)
224325	CL:2900	5	mixed, incl. Tetrahydromethanopterin S-methyltransferase MtrH subunit, and RACo, C-terminal
224325	CL:2915	5	mixed, incl. GHKL domain, and CGCAxxGCC motif
224325	CL:2928	16	mixed, incl. Coenzyme PQQ synthesis protein E, and Synthesis and degradation of ketone bodies
224325	CL:2930	8	mixed, incl. Synthesis and degradation of ketone bodies, and Alkylhydroperoxidase AhpD core
224325	CL:2948	6	mixed, incl. Coenzyme PQQ synthesis protein E, and Cytoplasmic tRNA 2-thiolation protein 1
224325	CL:2959	11	mostly uncharacterized, incl. Sugar transport, and Phenylacetate-CoA ligase
224325	CL:2962	5	mixed, incl. Sugar transport, and NAD-dependent epimerase/dehydratase
224325	CL:2986	10	mixed, incl. Divalent cation transporter, and Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
224325	CL:2988	5	mixed, incl. Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family, and Acetate-CoA ligase [ADP-forming], alpha domain
224325	CL:3010	102	mixed, incl. Transmembrane helix, and Winged helix-like DNA-binding domain superfamily
224325	CL:3011	78	mixed, incl. Winged helix-like DNA-binding domain superfamily, and integral component of membrane
224325	CL:3012	41	mixed, incl. Winged helix DNA-binding domain superfamily, and integral component of membrane
224325	CL:3013	23	mostly uncharacterized, incl. DTXR-type HTH domain, and regulation of transcription, DNA-templated
224325	CL:3015	17	mixed, incl. DTXR-type HTH domain, and regulation of transcription, DNA-templated
224325	CL:3017	5	mixed, incl. response to nickel cation, and ABC transporter, TroCD-like
224325	CL:3033	8	mixed, incl. Radical_SAM C-terminal domain, and RNA methyltransferase TrmH family
224325	CL:3058	18	mostly uncharacterized, incl. Major facilitator superfamily, and PFTB repeat
224325	CL:3059	12	mostly uncharacterized, incl. PFTB repeat, and ATP-cone domain
224325	CL:3062	5	mixed, incl. PFTB repeat, and ATP-cone domain
224325	CL:3082	6	mixed, incl. metalloendopeptidase activity, and Transmembrane secretion effector
224325	CL:3093	37	mostly uncharacterized, incl. Rubredoxin-like domain, and FAD/NAD(P)-binding domain
224325	CL:3094	24	mostly uncharacterized, incl. Heavy-metal-associated domain, and antioxidant activity
224325	CL:3095	16	mixed, incl. Heavy-metal-associated domain, and Rubredoxin-like domain
224325	CL:3097	5	mixed, incl. Flavoprotein WrbA-like, and Yjdj-type Gcn5-related N-acetyltransferase
224325	CL:31	2329	mixed, incl. metabolic process, and Membrane
224325	CL:3114	5	mixed, incl. Type I phosphodiesterase / nucleotide pyrophosphatase, and FeoA domain
224325	CL:312	5	DNA-directed RNA polymerase, subunit 2, and NGN domain
224325	CL:3127	5	mixed, incl. Redoxin, and Peptidase C45
224325	CL:3141	13	mostly uncharacterized, incl. ROK family, and Haemerythrin-like
224325	CL:3144	5	mixed, incl. Haemerythrin-like, and Domain of unknown function DUF1858
224325	CL:3157	5	mixed, incl. ROK family, and Rubredoxin
224325	CL:3166	24	mixed, incl. Regulator of K+ conductance, C-terminal domain superfamily, and Ferritin-like domain
224325	CL:3167	12	mixed, incl. Ferritin-like domain, and RNA surveillance
224325	CL:3170	5	Ferritin-like domain, and Desulfoferrodoxin
224325	CL:3181	5	mixed, incl. RNA surveillance, and Cation transporter
224325	CL:3190	12	mixed, incl. Regulator of K+ conductance, C-terminal domain superfamily, and Cation/H+ exchanger
224325	CL:3192	5	Cation/H+ exchanger, and Potassium/proton antiporter subunit KhtT
224325	CL:3213	58	mostly uncharacterized, incl. AAA domain, putative AbiEii toxin, Type IV TA system, and ABC-2 type transporter
224325	CL:3214	37	mostly uncharacterized, incl. Major facilitator superfamily, and Sphingolipid metabolism
224325	CL:3215	22	mostly uncharacterized, incl. Cytochrome c assembly protein, and Integrase core domain
224325	CL:3216	13	mixed, incl. Integrase core domain, and EamA domain
224325	CL:3218	5	Integrase core domain, and EamA domain
224325	CL:3242	6	mixed, incl. CcmB protein, and Cytochrome c-type biogenesis protein CcmC
224325	CL:3258	15	mixed, incl. Sphingolipid metabolism, and arginine catabolic process
224325	CL:3260	10	mixed, incl. Sphingolipid metabolism, and Cytochrome ubiquinol oxidase subunit 1
224325	CL:3262	5	Cytochrome ubiquinol oxidase subunit 1, and Hypusine biosynthesis
224325	CL:328	6	Bacterial secretion system
224325	CL:3287	21	mixed, incl. AAA domain, putative AbiEii toxin, Type IV TA system, and ABC-2 family transporter protein
224325	CL:3288	12	mostly uncharacterized, incl. Carbohydrate-binding-like fold, and ABC-2 family transporter protein
224325	CL:3290	5	mixed, incl. Carbohydrate-binding-like fold, and ABC-2 family transporter protein
224325	CL:3302	5	mixed, incl. Daunorubicin resistance ABC transporter membrane protein, and Daunorubicin resistance ABC transporter ATP-binding subunit DrrA
224325	CL:3312	6	mixed, incl. Rhomboid family, and Protein of unknown function (DUF2813)
224325	CL:3328	182	mixed, incl. 4Fe-4S ferredoxin-type, iron-sulphur binding domain, and Membrane
224325	CL:3329	172	mixed, incl. 4Fe-4S ferredoxin, iron-sulphur binding, conserved site, and Membrane
224325	CL:3330	131	mixed, incl. 4Fe-4S ferredoxin, iron-sulphur binding, conserved site, and Membrane
224325	CL:3331	105	mixed, incl. 4Fe-4S ferredoxin, iron-sulphur binding, conserved site, and Membrane
224325	CL:3332	78	mixed, incl. 4Fe-4S ferredoxin, iron-sulphur binding, conserved site, and Electron transport
224325	CL:3333	66	mixed, incl. 4Fe-4S ferredoxin, iron-sulphur binding, conserved site, and Electron transport
224325	CL:3334	52	mixed, incl. 4Fe-4S ferredoxin, iron-sulphur binding, conserved site, and Electron transport
224325	CL:3335	46	mixed, incl. 4Fe-4S ferredoxin, iron-sulphur binding, conserved site, and NarG-like domain
224325	CL:3337	21	mixed, incl. Methyl-viologen-reducing hydrogenase, delta subunit, and Peptidase A31 family
224325	CL:3339	11	mixed, incl. Methyl-viologen-reducing hydrogenase, delta subunit, and 4Fe-4S binding domain
224325	CL:3341	6	mixed, incl. Nickel-dependent hydrogenase, and [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily
224325	CL:3368	5	mixed, incl. HypF finger, and Carbamoyl dehydratase HypE
224325	CL:3381	23	mixed, incl. Electron transport, and Sulfur metabolism
224325	CL:3383	14	Sulfur metabolism, and Electron transport
224325	CL:3385	6	Sulfur metabolism, and DsrC like protein
224325	CL:339	26	mixed, incl. RNA modification, and Ribosome biogenesis
224325	CL:34	2324	mixed, incl. metabolic process, and Membrane
224325	CL:3401	5	Electron transport
224325	CL:3417	5	mixed, incl. Multihaem cytochrome, and Nitrogen metabolism
224325	CL:342	14	mixed, incl. Ribosome biogenesis, and RNA methylation
224325	CL:3427	5	mixed, incl. Phosphoribosyl-ATP pyrophosphohydrolase, and Type II secretion system F domain
224325	CL:3437	14	mixed, incl. LUD domain, and amine-lyase activity
224325	CL:3439	5	amine-lyase activity, and SAM-binding methyltransferase MPBQ/MBSQ
224325	CL:344	5	Ribosome biogenesis, and cyclase activity
224325	CL:3451	7	mixed, incl. LUD domain, and L-lactate permease
224325	CL:3464	12	mixed, incl. 4Fe-4S binding domain, and iron ion transport
224325	CL:3467	5	mixed, incl. Tetrathionate reductase subunit A, MopB domain, and TorD-like superfamily
224325	CL:3487	27	mixed, incl. Proton-conducting membrane transporter, and Oxidative phosphorylation
224325	CL:3488	21	mixed, incl. Proton-conducting membrane transporter, and Oxidative phosphorylation
224325	CL:3489	11	mixed, incl. Proton-conducting membrane transporter, and NADH dehydrogenase
224325	CL:3493	6	mixed, incl. Proton-conducting membrane transporter, and NADH dehydrogenase
224325	CL:35	2306	mixed, incl. metabolic process, and Membrane
224325	CL:3510	10	mixed, incl. Cupredoxin, and Ubiquinone
224325	CL:3513	5	Cupredoxin, and Cytochrome c
224325	CL:3530	5	mixed, incl. Winged helix DNA-binding domain (DUF1495), and Ferric reductase like transmembrane component
224325	CL:3541	22	mixed, incl. Dinitrogenase iron-molybdenum cofactor, and CobQ/CobB/MinD/ParA nucleotide binding domain
224325	CL:3542	16	mixed, incl. Dinitrogenase iron-molybdenum cofactor, and Cohesin domain
224325	CL:3543	11	mixed, incl. Cohesin domain, and MTH1175 domain
224325	CL:3546	5	MTH1175 domain, and CobQ/CobB/MinD/ParA nucleotide binding domain
224325	CL:3564	5	mixed, incl. Polysulfide reductase, and Phospholipid methyltransferase 
224325	CL:3573	6	mixed, incl. lipid modification, and ATP-NAD kinase, PpnK-type, C-terminal
224325	CL:3591	41	mixed, incl. Sulfur relay system, and Cysteine and methionine metabolism
224325	CL:3592	35	mixed, incl. Sulfur relay system, and Cysteine and methionine metabolism
224325	CL:3593	26	mixed, incl. Sulfur relay system, and Molybdenum
224325	CL:3594	20	mixed, incl. Sulfur relay system, and MoaB/Mog domain
224325	CL:3595	11	Folate biosynthesis, and MoaD, archaeal-type
224325	CL:3597	5	MoaB/Mog domain, and Molybdenum cofactor guanylyltransferase
224325	CL:36	2299	mixed, incl. metabolic process, and Membrane
224325	CL:360	5	tRNA (guanine-N2-)-methyltransferase activity, and Helicase
224325	CL:3617	5	mixed, incl. DsrE2-like family, and Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE
224325	CL:3633	6	Molybdenum, and TOBE domain
224325	CL:3645	6	Deaminase MtaD/DadD, and Spermidine biosynthesis
224325	CL:3661	6	mixed, incl. GYD domain, and Archaeal transcriptional regulator TrmB
224325	CL:3673	8	mixed, incl. Protein of unknown function DUF2589, and BtpA family
224325	CL:3691	29	mostly uncharacterized, incl. Carbohydrate kinase, FGGY, conserved site, and FAD-linked oxidase, C-terminal
224325	CL:3692	21	mostly uncharacterized, incl. Carbohydrate kinase, FGGY, conserved site, and Alpha/beta hydrolase family
224325	CL:3693	14	mixed, incl. Glycerophospholipid metabolism, and Archease
224325	CL:3696	7	mixed, incl. Ndr family, and UPF0145 domain superfamily
224325	CL:3721	5	mixed, incl. CGGC domain, and Xylulokinase
224325	CL:3735	5	mixed, incl. Membrane protein of 12 TMs, and Domain of unknown function DUF1724
224325	CL:3749	10	mixed, incl. Phosphodiesterase MJ0936/Vps29, and Protein of unknown function DUF389
224325	CL:3751	5	mixed, incl. Protein of unknown function DUF389, and CorA-like Mg2+ transporter protein
224325	CL:377	5	pseudouridine synthesis
224325	CL:3776	11	mixed, incl. CARDB domain, and Protein of unknown function DUF333
224325	CL:3777	6	mixed, incl. CARDB domain, and Protein of unknown function DUF333
224325	CL:3788	5	mixed, incl. Presenilin/signal peptide peptidase, and PIN domain
224325	CL:3798	13	mostly uncharacterized, incl. PPC domain, and Aconitase X subunit 2, putative
224325	CL:38	2281	mixed, incl. metabolic process, and Membrane
224325	CL:3801	5	mixed, incl. Aconitase X subunit 2, putative, and Protein of unknown function (DUF521)
224325	CL:3814	5	mixed, incl. PPC domain, and Domain of unknown function DUF1624
224325	CL:3823	51	mixed, incl. Quorum sensing, and NMT1/THI5 like
224325	CL:3825	35	Quorum sensing, and UTRA domain
224325	CL:3826	27	Quorum sensing, and UTRA domain
224325	CL:3828	20	Quorum sensing
224325	CL:3829	15	Quorum sensing
224325	CL:3830	10	Quorum sensing
224325	CL:3831	5	Branched-chain amino acid ATP-binding cassette transporter, and ABC transporter, permease
224325	CL:3840	5	Periplasmic binding protein domain, and ABC transporter, permease
224325	CL:3849	5	amino acid transport, and ABC transporter, permease
224325	CL:3858	5	mixed, incl. PrkA AAA domain, and Periplasmic binding protein domain
224325	CL:3880	5	Oligopeptide/dipeptide ABC transporter, C-terminal, and Solute-binding protein family 5
224325	CL:3895	15	mixed, incl. NMT1/THI5 like, and MetI-like superfamily
224325	CL:3899	6	mixed, incl. NMT1/THI5 like, and Protein of unknown function DUF1850
224325	CL:39	2264	mixed, incl. metabolic process, and Membrane
224325	CL:390	25	DNA replication, and DNA-dependent ATPase activity
224325	CL:3913	6	mixed, incl. NLPA lipoprotein, and Fumarylacetoacetase-like, C-terminal
224325	CL:392	16	DNA replication, and DNA recombination
224325	CL:3924	24	mixed, incl. Pyruvate-formate lyase-activating enzyme, predicted, and Protein of unknown function DUF131
224325	CL:3925	13	mixed, incl. Pyruvate-formate lyase-activating enzyme, predicted, and MEMO1 family
224325	CL:3927	7	mixed, incl. Citrate transporter, and Glutamate--cysteine ligase, GCS2
224325	CL:393	11	DNA replication, and damaged DNA binding
224325	CL:395	6	replisome, and AAA domain
224325	CL:3952	7	mixed, incl. Protein of unknown function DUF131, and DNA N-glycosylase activity
224325	CL:3971	29	mixed, incl. Peptidase M73, camelysin, and Subtilase family
224325	CL:3973	18	mixed, incl. Peptidase M73, camelysin, and Subtilase family
224325	CL:3975	10	Peptidase M73, camelysin, and Subtilase family
224325	CL:3979	5	Peptidase S26B, and Peptidase M73, camelysin
224325	CL:3997	6	mixed, incl. alanine metabolic process, and Uncharacterised protein MJ0570, ATP-binding
224325	CL:40	2254	mixed, incl. metabolic process, and Membrane
224325	CL:4015	7	mixed, incl. indolepyruvate ferredoxin oxidoreductase activity, and PGF-CTERM archaeal protein-sorting signal
224325	CL:4029	5	mixed, incl. Coenzyme A biosynthesis, and Protein of unknown function DUF84
224325	CL:4045	35	mixed, incl. KaiC-like domain, and PAC motif
224325	CL:4046	20	mixed, incl. UspA, and Sulfite exporter TauE/SafE
224325	CL:4047	15	mixed, incl. MetI-like superfamily, and PAC motif
224325	CL:4049	8	mixed, incl. Histidine kinase-like ATPase domain, and Glycine betaine transport ATP-binding subunit
224325	CL:4067	5	mixed, incl. Pectinacetylesterase, and Alcohol dehydrogenase, iron-type, conserved site
224325	CL:4076	5	mixed, incl. Uncharacterized protein MJ0871-like, and Domain of unknown function DUF22
224325	CL:4085	15	mixed, incl. KaiC-like domain, and Protein of unknown function DUF1152
224325	CL:4086	10	mixed, incl. KaiC-like domain, and His Kinase A (phospho-acceptor) domain
224325	CL:4087	5	mixed, incl. His Kinase A (phospho-acceptor) domain, and DNA recombination and repair protein RecA-like, ATP-binding domain
224325	CL:4096	5	KaiC-like domain, and 4Fe-4S binding domain
224325	CL:4105	5	mixed, incl. Protein of unknown function DUF1152, and Rad51
224325	CL:4114	19	mostly uncharacterized, incl. Symport, and Rotamase
224325	CL:4115	10	mixed, incl. Aquaporin-like, and LarA-like, N-terminal
224325	CL:4117	5	mixed, incl. LarA-like, N-terminal, and Nickel insertion protein
224325	CL:4136	5	Signal, and plasma membrane
224325	CL:414	5	DNA polymerase activity, and enzyme regulator activity
224325	CL:4151	24	mostly uncharacterized, incl. HpaB/PvcC/4-BUDH, and ABC transporter, permease
224325	CL:4152	17	mixed, incl. HpaB/PvcC/4-BUDH, and ABC transporter, permease
224325	CL:4153	12	mixed, incl. HpaB/PvcC/4-BUDH, and ABC transporter, permease
224325	CL:4155	6	mixed, incl. HpaB/PvcC/4-BUDH, and ABC transporter substrate-binding protein PnrA-like
224325	CL:4176	5	mixed, incl. CHASE4 domain, and ADP-ribosylglycohydrolase
224325	CL:4185	7	mixed, incl. MraZ domain, and Haemolysin A /rRNA methyltransferase TlyA
224325	CL:4198	19	mostly uncharacterized, incl. RNA repair, and Kelch motif
224325	CL:4199	14	mostly uncharacterized, incl. RNA repair, and Phosphoesterase, HXTX
224325	CL:42	2238	mixed, incl. metabolic process, and Membrane
224325	CL:4202	7	mixed, incl. RNA repair, and Phosphoesterase, HXTX
224325	CL:4226	5	mixed, incl. Kelch motif, and Phospholipase C/D
224325	CL:4235	14	mostly uncharacterized, incl. Roadblock/LC7 domain, and Protein of unknown function DUF2226
224325	CL:4236	7	mixed, incl. Roadblock/LC7 domain, and Protein of unknown function DUF2226
224325	CL:4249	7	mixed, incl. ST1585, MBL-fold, and Transcription regulator TrmB, N-terminal
224325	CL:4262	14	mixed, incl. Protein of unknown function DUF1102, and transposition
224325	CL:4264	6	Protein of unknown function DUF1102, and Peptidase S26A, signal peptidase I, serine active site
224325	CL:4278	6	mixed, incl. transposition, and GHMP kinase group 1
224325	CL:4289	67	mostly uncharacterized, incl. Antiviral defense, and Nucleotidyltransferase domain
224325	CL:4290	45	mixed, incl. Antiviral defense, and RAMP superfamily
224325	CL:4291	34	mixed, incl. Antiviral defense, and RAMP superfamily
224325	CL:4292	21	mixed, incl. Antiviral defense, and RAMP superfamily
224325	CL:4294	15	mixed, incl. RAMP superfamily, and Antiviral defense
224325	CL:4297	6	mixed, incl. CRISPR-associated protein, Cas5, and CRISPR type I-A/APERN-associated protein Csa5
224325	CL:430	5	Topoisomerase
224325	CL:4312	5	RAMP superfamily, and AF1862-like domain superfamily
224325	CL:4333	13	mixed, incl. Antiviral defense, and CRISPR associated protein Cas6
224325	CL:4335	5	mixed, incl. CRISPR-associated protein Cas5, N-terminal, and CRISPR-associated  Cas3-type HD domain
224325	CL:4347	6	Antiviral defense, and CRISPR associated protein Cas6
224325	CL:4358	11	mostly uncharacterized, incl. GGDEF domain, and Archael gltB
224325	CL:4359	6	mixed, incl. GGDEF domain, and Archael gltB
224325	CL:4370	5	mixed, incl. Protein of unknown function DUF86, and PGF-CTERM archaeal protein-sorting signal
224325	CL:4379	22	mostly uncharacterized, incl. Nucleotidyltransferase domain, and PIN domain
224325	CL:4381	14	mostly uncharacterized, incl. PIN domain, and TTHA1013/TTHA0281-like
224325	CL:4382	7	mixed, incl. Domain of unknown function DUF1156, and Toxin-antitoxin system, RelE/ParE toxin family
224325	CL:4395	7	mixed, incl. PIN domain, and TTHA1013/TTHA0281-like
224325	CL:44	2228	mixed, incl. metabolic process, and Membrane
224325	CL:440	5	mixed, incl. Protein MJ0935, and Shikimate kinase
224325	CL:4413	5	mixed, incl. Protein of unknown function DUF499
224325	CL:4422	39	mostly uncharacterized, incl. Sulfite exporter TauE/SafE, and Uncharacterised protein family UPF0324, prokaryote
224325	CL:4424	29	mixed, incl. Uncharacterised protein family UPF0324, prokaryote, and Sulfite exporter TauE/SafE
224325	CL:4425	21	mixed, incl. Uncharacterised protein family UPF0324, prokaryote, and Sulfite exporter TauE/SafE
224325	CL:4426	13	mixed, incl. Uncharacterised protein family UPF0324, prokaryote, and PAS fold
224325	CL:4428	6	Uncharacterised protein family UPF0324, prokaryote, and PAS fold
224325	CL:4452	5	Sulfite exporter TauE/SafE, and Putative antitoxin
224325	CL:4467	5	mixed, incl. Invasin/intimin cell-adhesion fragments, and Signal
224325	CL:4488	6	mixed, incl. Uncharacterised UPF0058 superfamily, and Winged helix-turn-helix
224325	CL:45	2189	mixed, incl. metabolic process, and Membrane
224325	CL:4506	5	mixed, incl. von Willebrand factor, type A, and Flagellin/pilin, N-terminal
224325	CL:4522	13	mixed, incl. Domain of unknown function DUF2281, and Piwi domain
224325	CL:4523	7	mixed, incl. Piwi domain, and Uncharacterised MFS-type transporter YbfB
224325	CL:4536	6	mixed, incl. Domain of unknown function DUF2281, and HEPN domain
224325	CL:4547	10	mixed, incl. EVE domain, and ATP binding protein MinD
224325	CL:4549	5	mixed, incl. EVE domain, and Transglutaminase-like
224325	CL:4566	17	mixed, incl. Signal, and DeoR-like helix-turn-helix domain
224325	CL:4567	10	mixed, incl. DeoR-like helix-turn-helix domain, and Halocin C8-like bacteriocin domain
224325	CL:4569	5	mixed, incl. Halocin C8-like bacteriocin domain, and Signal
224325	CL:457	21	mixed, incl. Holliday junction DNA helicase ruvB N-terminus, and protein binding
224325	CL:4586	7	Signal, and integral component of membrane
224325	CL:459	10	mixed, incl. Histone-fold, and Holliday junction DNA helicase ruvB N-terminus
224325	CL:46	2122	mixed, incl. metabolic process, and Membrane
224325	CL:460	5	Histone-fold, and SNF2 family N-terminal domain
224325	CL:4602	16	PIN domain, and AF2212-like domain superfamily
224325	CL:4604	11	PIN domain, and AF2212-like domain superfamily
224325	CL:4607	5	Large family of predicted nucleotide-binding domains, and AF2212-like domain superfamily
224325	CL:4634	5	mixed, incl. Iron dependent repressor, N-terminal DNA binding domain, and Signal
224325	CL:4646	18	mixed, incl. AF2212-like domain superfamily, and PIN-like domain superfamily
224325	CL:4647	12	mixed, incl. AF2212-like domain superfamily, and Toxin-antitoxin system, YafQ-like toxin
224325	CL:4650	6	mixed, incl. Toxin-antitoxin system, YafQ-like toxin, and Toxin
224325	CL:4670	6	mixed, incl. Protein of unknown function DUF3368, and Uncharacterised protein family UPF0175
224325	CL:469	5	mixed, incl. Dna2, and RuvB-like
224325	CL:4692	5	mixed, incl. DNA polymerase beta palm , and Higher Eukarytoes and Prokaryotes Nucleotide-binding domain
224325	CL:47	2108	mixed, incl. metabolic process, and Membrane
224325	CL:4709	11	mixed, incl. Toxin-antitoxin system, RelE/ParE toxin domain superfamily, and Protein of unknown function DUF433
224325	CL:4711	5	mixed, incl. Toxin, and Toxin-antitoxin system, RelE/ParE toxin domain superfamily
224325	CL:4754	5	Yip1 domain, and integral component of membrane
224325	CL:48	2094	mixed, incl. metabolic process, and Membrane
224325	CL:483	6	Stress response, and Thermosome, archaeal
224325	CL:49	2075	mixed, incl. metabolic process, and Membrane
224325	CL:498	27	mixed, incl. catalytic complex, and RNA 5'-end processing
224325	CL:50	2051	mixed, incl. metabolic process, and Membrane
224325	CL:500	13	mixed, incl. Exosome, and Nucleophile aminohydrolases, N-terminal
224325	CL:502	7	Exosome, and Penicillin amidase
224325	CL:51	2032	mixed, incl. metabolic process, and Membrane
224325	CL:52	1997	mixed, incl. metabolic process, and Membrane
224325	CL:528	12	mixed, incl. RNA 5'-end processing, and Prefoldin
224325	CL:529	6	RNA 5'-end processing, and YggU-like superfamily
224325	CL:53	1988	mixed, incl. metabolic process, and Membrane
224325	CL:54	1959	mixed, incl. metabolic process, and Membrane
224325	CL:540	6	mixed, incl. Prefoldin, and PDCD5-like
224325	CL:55	1935	mixed, incl. metabolic process, and Membrane
224325	CL:552	11	mixed, incl. Pantothenate and CoA biosynthesis, and NYN domain
224325	CL:555	5	mixed, incl. Pantoate kinase, and CoaB-like superfamily
224325	CL:56	1884	mixed, incl. metabolic process, and Membrane
224325	CL:57	1871	mixed, incl. metabolic process, and Membrane
224325	CL:58	1859	mixed, incl. metabolic process, and Membrane
224325	CL:582	8	mixed, incl. Gcp-like domain, and S27a-like superfamily
224325	CL:59	1845	mixed, incl. metabolic process, and Membrane
224325	CL:60	1816	mixed, incl. metabolic process, and Membrane
224325	CL:61	1634	mixed, incl. metabolic process, and Membrane
224325	CL:611	7	mixed, incl. carboxylic ester hydrolase activity, and Tubulin/FtsZ, C-terminal
224325	CL:62	1576	mixed, incl. metabolic process, and Membrane
224325	CL:624	13	mostly uncharacterized, incl. PDZ domain, and PHP-associated
224325	CL:626	5	mixed, incl. PDZ domain, and Divalent ion tolerance protein, CutA
224325	CL:63	1474	mixed, incl. metabolic process, and Membrane
224325	CL:638	6	mixed, incl. Translin family, and Wyosine base formation
224325	CL:64	1304	mixed, incl. metabolic process, and Membrane
224325	CL:649	129	mostly uncharacterized, incl. Oxidative phosphorylation, and Coiled coil
224325	CL:65	1146	mixed, incl. metabolic process, and Membrane
224325	CL:650	114	mixed, incl. Coiled coil, and Transmembrane helix
224325	CL:651	101	mixed, incl. Coiled coil, and Transmembrane helix
224325	CL:652	95	mixed, incl. Coiled coil, and Transmembrane helix
224325	CL:653	85	mostly uncharacterized, incl. Coiled coil, and regulation of transcription, DNA-templated
224325	CL:654	78	mostly uncharacterized, incl. Coiled coil, and PRC-barrel domain
224325	CL:655	73	mostly uncharacterized, incl. DHH phosphoesterase superfamily, and P-loop containing nucleoside triphosphate hydrolase
224325	CL:656	62	mostly uncharacterized, incl. DHH phosphoesterase superfamily, and PRC-barrel domain
224325	CL:658	49	mostly uncharacterized, incl. DHH phosphoesterase superfamily, and PRC-barrel domain
224325	CL:66	1139	mixed, incl. metabolic process, and Membrane
224325	CL:660	39	mostly uncharacterized, incl. TGT, patch-forming C2 domain superfamily, and MarR family
224325	CL:662	32	mostly uncharacterized, incl. TGT, patch-forming C2 domain superfamily, and MarR family
224325	CL:663	20	mostly uncharacterized, incl. MarR family, and AAA domain
224325	CL:664	12	mostly uncharacterized, incl. Type IV leader peptidase family, and Archaeal Type IV pilin, N-terminal
224325	CL:666	5	mixed, incl. Type IV leader peptidase family, and Uncharacterised conserved protein HTH transcriptional regulator, archaea
224325	CL:67	1133	mixed, incl. metabolic process, and Membrane
224325	CL:678	5	mixed, incl. Archaeal Type IV pilin, N-terminal, and Protein of unknown function DUF655
224325	CL:68	1121	mixed, incl. cellular process, and Membrane
224325	CL:688	5	mixed, incl. SepF-like superfamily, and Zinc finger, ZPR1-type
224325	CL:69	1111	mixed, incl. cellular process, and Membrane
224325	CL:70	1057	mixed, incl. cellular process, and Membrane
224325	CL:702	12	mixed, incl. TGT, patch-forming C2 domain superfamily, and DHH phosphoesterase superfamily
224325	CL:704	6	mixed, incl. TGT, patch-forming C2 domain superfamily, and NAC domain
224325	CL:71	891	mixed, incl. cellular process, and Metabolic pathways
224325	CL:72	881	mixed, incl. cellular process, and Metabolic pathways
224325	CL:73	855	mixed, incl. cellular process, and Metabolic pathways
224325	CL:74	845	mixed, incl. cellular process, and Metabolic pathways
224325	CL:742	7	mixed, incl. T7 endonuclease I-like, and Diadenylate cyclase, DacZ-type
224325	CL:75	802	mixed, incl. cellular process, and Metabolic pathways
224325	CL:758	11	mixed, incl. HTH DNA binding domain, and Dienelactone hydrolase
224325	CL:76	790	mixed, incl. cellular process, and Metabolic pathways
224325	CL:760	5	HTH DNA binding domain, and HIT-like superfamily
224325	CL:77	775	mixed, incl. cellular process, and Metabolic pathways
224325	CL:770	5	mixed, incl. Dienelactone hydrolase, and Armadillo-like helical
224325	CL:779	11	mostly uncharacterized, incl. PLD-like domain, and MazG-like family
224325	CL:78	740	mixed, incl. cellular process, and Metabolic pathways
224325	CL:782	5	mixed, incl. PLD-like domain, and GTP cyclohydrolase MptA
224325	CL:79	701	mixed, incl. cellular process, and Metabolic pathways
224325	CL:8	2378	mixed, incl. metabolic process, and Membrane
224325	CL:80	453	mixed, incl. macromolecule metabolic process, and Coiled coil
224325	CL:800	5	mixed, incl. ACT domain, and Protein of unknown function DUF373
224325	CL:809	7	mixed, incl. Helix-turn-helix domain, and Flavin reductase like domain
224325	CL:81	447	mixed, incl. macromolecule metabolic process, and Coiled coil
224325	CL:82	433	mixed, incl. macromolecule metabolic process, and Coiled coil
224325	CL:822	10	mixed, incl. NIL domain, and zinc finger
224325	CL:823	5	mixed, incl. NIL domain, and zinc finger
224325	CL:83	412	mixed, incl. macromolecule metabolic process, and Coiled coil
224325	CL:832	5	mixed, incl. IstB-like ATP binding protein, and Thiolase, acyl-enzyme intermediate active site
224325	CL:84	283	macromolecule metabolic process, and Coiled coil
224325	CL:841	6	mixed, incl. ERCC4 domain, and Amidohydrolase-related
224325	CL:85	270	macromolecule metabolic process, and P-loop containing nucleoside triphosphate hydrolase
224325	CL:852	13	mixed, incl. Beta-lactamase superfamily domain, and MTH1187/YkoF-like
224325	CL:854	5	mixed, incl. EF-1 guanine nucleotide exchange domain, and Peptide-modifying radical SAM enzyme putative, AF0577
224325	CL:86	263	macromolecule metabolic process, and P-loop containing nucleoside triphosphate hydrolase
224325	CL:868	5	mixed, incl. Creatinase, N-terminal, and Arsenical-resistance protein Acr3
224325	CL:877	15	Hydrogen ion transport, and ATP synthase subunit C
224325	CL:88	257	macromolecule metabolic process, and Protein export
224325	CL:880	10	Hydrogen ion transport, and ATP synthase subunit C
224325	CL:884	5	ATP synthesis
224325	CL:89	246	macromolecule metabolic process, and Protein export
224325	CL:90	231	macromolecule metabolic process, and Protein export
224325	CL:906	21	mixed, incl. Aminoacyl-tRNA biosynthesis, and Asparagine synthase
224325	CL:907	16	Aminoacyl-tRNA biosynthesis, and Asparagine synthase
224325	CL:909	7	mixed, incl. Amidase, and GatB domain
224325	CL:91	204	macromolecule metabolic process, and Protein export
224325	CL:928	5	mixed, incl. Asparagine synthase, and Flavodoxin-like fold
224325	CL:93	179	macromolecule metabolic process, and Protein export
224325	CL:938	5	mixed, incl. AI-2E family transporter, and Uncharacterized ArCR, COG1888
224325	CL:94	173	macromolecule metabolic process, and Protein export
224325	CL:948	10	mixed, incl. Phosphate transport, and PBP superfamily domain
224325	CL:95	148	gene expression, and Protein export
224325	CL:951	5	Phosphate transport, and PBP superfamily domain
224325	CL:96	122	cellular macromolecule biosynthetic process, and Protein export
224325	CL:97	116	translation, and Transcription
224325	CL:975	5	peptidyl-lysine modification, and DREV methyltransferase
224325	CL:98	93	translation
224325	CL:986	245	Metabolic pathways, and NAD(P)-binding domain superfamily
224325	CL:987	236	Metabolic pathways, and ATP-grasp fold, subdomain 1
224325	CL:988	222	Metabolic pathways, and ATP-grasp fold, subdomain 1
224325	CL:989	203	Biosynthesis of antibiotics, and small molecule biosynthetic process
224325	CL:990	116	Biosynthesis of amino acids, and nucleoside monophosphate metabolic process
224325	CL:991	87	Amino-acid biosynthesis, and nucleoside monophosphate metabolic process
224325	CL:992	47	Amino-acid biosynthesis, and Peptidase M20
224325	CL:993	26	Phenylalanine, tyrosine and tryptophan biosynthesis, and Histidine metabolism
224325	CL:994	20	Aromatic amino acid biosynthesis, and Histidine metabolism
224325	CL:995	14	Tryptophan biosynthesis, and Histidine metabolism
224325	CL:998	5	Histidine metabolism
